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  1. Notes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Notes Notes Why the June 1995 ERSUG Meeting is Important Bill McCurdy describes below a competitive process through which a decision will be made by MICS Division (formerly the OSC) in the June, 1995 timeframe to: (1) possibly move NERSC to Lawrence Berkeley National Laboratory, and (2) redefine to some extent the mission of the Center. All of this would be effected within a significantly reduced cost envelope. The LLNL proposal to keep NERSC where it is and the LBL proposal may soon be

  2. Notes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Notes Notes Live Media Streaming via RealPlayer Media streaming of these lectures will be provided via RealPlayer. Users of Windows- or Macintosh-based computers will be able to see and hear the presentation by way of the following procedures. 1. Download and open the slide files onto your computer. 2. Make certain you have the current version of RealPlayer installed. These are available at the Real Free Player Download web site 3. Start the RealPlayer application, and then enter the following

  3. OTS NOTE

    Office of Legacy Management (LM)

    c3 Alexander Williams FROM: Ed Mitchellcm SUBJECT: Babcock and Wilcox Elimination Recommendation The purpose of this note is to provide you with certain inf regarding the ...

  4. OTS NOTE

    Office of Legacy Management (LM)

    941 OTS NOTE DATE: July 2, 1990 TO: W. Alexander Williams FROM : Don Mackenzie d%? SUBJECT: Elimination of 3 Facilities from NSRAP . + 9 Enclosed are elimination recommendations...

  5. Blue Note

    ScienceCinema (OSTI)

    Murray Gibson

    2010-01-08

    Argonne's Murray Gibson is a physicist whose life's work includes finding patterns among atoms. The love of distinguishing patterns also drives Gibson as a musician and Blues enthusiast."Blue" notes are very harmonic notes that are missing from the equal temperament scale.The techniques of piano blues and jazz represent the melding of African and Western music into something totally new and exciting.

  6. Blue Note

    SciTech Connect (OSTI)

    Murray Gibson

    2007-04-27

    Argonne's Murray Gibson is a physicist whose life's work includes finding patterns among atoms. The love of distinguishing patterns also drives Gibson as a musician and Blues enthusiast."Blue" notes are very harmonic notes that are missing from the equal temperament scale.The techniques of piano blues and jazz represent the melding of African and Western music into something totally new and exciting.

  7. OTS NOTE

    Office of Legacy Management (LM)

    OTS NOTE DATE: August 4, 1992 TO: Alexander Williams FROM: Ed Mitchell, Steve Fieser ' 565 SUBJECT: Revised Designation Package for Baker Brothers Site We have prepared the Designation Summary you requested for Baker Brothers Site, in Toledo, Ohio. This package supersedes the previous one provided on May 1, 1992, to reflect the documents that have since been finalized. The designationpackage consists of the following: o Designation Summary (8/4/92) o Authority Review (7/16/92) o Radiological

  8. TECHNICAL NOTE

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    TECHNICAL NOTE Broadband extreme-ultraviolet survey spectrometer for short-time-scale experiments B. E. Chapman, D. J. Den Hartog, and R. J. Fonck A fast and inexpensive spectrometer system has been developed to record extreme-UV impurity spectra in a magnetic-fusion-research device. To simplify the vacuum system, light is passed out of the spectrom- eter's vacuum to the detector with a sodium-salicylate-coated, fiber-optic coupler. This coupler is positioned so that the focal field is nearly

  9. Employee Show

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Where Science Inspires Art Fermilab Employee Art Show 2015 Exhibition Dates -September 18, 2015 November 30, 2015 Reception - September 23, 2015 5 7pm Eligibility: Any current...

  10. Light Show

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    9 Lightning - Nature's Light Show Lightning provides one of nature's most spectacular displays of energy. Though fascinating to observe, lightning can be dangerous and deadly. Protecting ARM instruments from lightning damage is vital. Putting equipment worth millions of dollars into open fields (Photo: NOAA) ARM Facilities Newsletter is published by Argonne National Laboratory, a multiprogram laboratory operated by The University of Chicago under contract W-31-109-Eng-38 with the U.S. Department

  11. Notes for Visualization Requirememnts

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Notes for Visualization Requirememnts Notes from June 5, 2002, Visualization Requirements for DOE-Sponsored Computational Science and Engineering Applications A DOE Workshop to Be ...

  12. Property:ExplorationNotes | Open Energy Information

    Open Energy Information (Open El) [EERE & EIA]

    the property "ExplorationNotes" Showing 1 page using this property. R RAPIDOverviewGeothermalExplorationCalifornia + The Geothermal Resources Prospecting Permit (PRC...

  13. Calculation note review

    SciTech Connect (OSTI)

    Ramble, A.L.

    1996-09-30

    This document contains a review of the calculation notes which were prepared for the Tank Waste Remediation System Basis for Interim Operation.

  14. ARM - Field Notes Article

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    CenterField NotesField Notes Article Media Contact Hanna Goss hanna-dot-goss-at-pnnl-dot-gov @armnewsteam Field Notes Blog Topics Field Notes118 AGU 3 AMIE 10 ARM Aerial Facility 2 ARM Mobile Facility 1 7 ARM Mobile Facility 2 47 ARM Mobile Facility 3 1 BAECC 1 BBOP 4 CARES 1 Data Quality Office 2 ENA 2 GOAMAZON 7 HI-SCALE 5 LASIC 3 MAGIC 15 MC3E 17 PECAN 3 SGP 8 STORMVEX 29 TCAP 3 Search News Search Blog News Center All Categories What's this? Social Media Guidance News Center All Categories

  15. Notes and Action Items

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Notes and Action Items Notes and Action Items Report on the NUGEX business meeting of June 6, 2000, in Oak Ridge Minute notes by Bas Braams First of all, many thanks to the organizers of the preceding NUG meeting: Roberta Boucher, David Dean, Brian Hingerty, Bill Kramer, Donald Spong and Malcolm Stocks. Likewise thanks to Brian Hingerty and Mike Minkoff for organizing the Users Helping Users events, and to Tom DeBoni, Osni Marques, Jeffrey Squyres and David Turner for the NERSC training classes.

  16. Navigation Labels and Approval

    Energy.gov [DOE]

    EERE has commonly used and approved navigation labels. To maintain consistency in navigation across EERE, the EERE Template Coordinator reviews and approves requests for new navigation labels and...

  17. Meeting Notes and Presentations

    Office of Environmental Management (EM)

    Corporate Board Notes and Slides Notes from EM Corporate QA Board Tele-Conference - February 22, 2010 1 of 2 General: Attendance of voting board members was documented. All members were present or had a representative present on the call. Previous 5 Focus Areas: Dave Tuttel presented the proposed closeout of the previous 5 focus areas for the EM Corporate Board. * Focus Area 1 (Requirements Flow Down) - Board voted to close the focus area (unanimous) * Focus Area 2 (Adequate NQA-1 Suppliers) -

  18. VOL2NOTE.CHP:Corel VENTURA

    Gasoline and Diesel Fuel Update

    B Explanatory Notes The following Explanatory Notes are provided to assist in understanding and interpreting the data presented in this publication. * Note 1. Petroleum Supply Reporting System * Note 2. Monthly Petroleum Supply Reporting System * Note 3. Technical Notes for Detailed Statistics Tables * Note 4. Domestic Crude Oil Production * Note 5. Export Data * Note 6. Quality Control and Data Revision * Note 7. Frames Maintenance * Note 8. Descriptive Monthly Statistics * Note 9. Practical

  19. Template:Note | Open Energy Information

    Open Energy Information (Open El) [EERE & EIA]

    search Note Note: Usage Method 1 The following displays the note icon and the word 'Note:'. You can follow this with whatever textimagesmarkup you like, and it works...

  20. Notes and Definitions

    Weekly Natural Gas Storage Report

    Notes and Definitions This report tracks U.S. natural gas inventories held in underground storage facilities. The weekly stocks generally are the volumes of working gas as of the report date. The "net change" in reported stock levels reflects all events affecting working gas in storage, including injections, withdrawals, and reclassifications between base and working gas. The "implied flow" estimate represents movements of working natural gas into or out of underground

  1. AIRMaster+ Release Notes | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Release Notes AIRMaster+ Release Notes AIRMaster+ (Version 1.2.7) Release Notes Release Notes (Version 1.2.7) (296.45 KB) More Documents & Publications AIRMaster+ Software Tool Brochure AIRMaster+ User Manual AIRMaster+ Tool Introduction

  2. Show Me PACE

    Energy.gov [DOE]

    In July 2010 Missouri enacted the Property Assessed Clean Energy Act. In June 2015, Show Me PACE was established under this law as a Clean Energy Development Board. PACE financing allows property...

  3. Post-Show Tips

    Energy.gov [DOE]

    These guidelines are designed to help you with the post-show process. This page includes tips for tearing down your exhibit, shipping the exhibit, and collecting your bills.

  4. Research Notes and Information References

    Energy Science and Technology Software Center (OSTI)

    1994-12-01

    The RNS (Research Notes System) is a set of programs and databases designed to aid the research worker in gathering, maintaining, and using notes taken from the literature. The sources for the notes can be books, journal articles, reports, private conversations, conference papers, audiovisuals, etc. The system ties the databases together in a relational structure, thus eliminating data redundancy while providing full access to all the information. The programs provide the means for access andmore » data entry in a way that reduces the key-entry burden for the user. Each note has several data fields. Included are the text of the note, the subject classification (for retrieval), and the reference identification data. These data are divided into four databases: Document data - title, author, publisher, etc., fields to identify the article within the document; Note data - text and page of the note; Sublect data - subject categories to ensure uniform spelling for searches. Additionally, there are subsidiary files used by the system, including database index and temporary work files. The system provides multiple access routes to the notes, both structurally (access method) and topically (through cross-indexing). Output may be directed to a printer or saved as a file for input to word processing software.« less

  5. Capacitive label reader

    DOE Patents [OSTI]

    Arlowe, H. Duane

    1985-01-01

    A capacitive label reader includes an outer ring transmitting portion, an inner ring transmitting portion, and a plurality of insulated receiving portions. A label is the mirror-image of the reader except that identifying portions corresponding to the receiving portions are insulated from only one of two coupling elements. Positive and negative pulses applied, respectively, to the two transmitting rings biased a CMOS shift register positively to either a 1 or 0 condition. The output of the CMOS may be read as an indication of the label.

  6. Capacitive label reader

    DOE Patents [OSTI]

    Arlowe, H.D.

    1983-07-15

    A capacitive label reader includes an outer ring transmitting portion, an inner ring transmitting portion, and a plurality of insulated receiving portions. A label is the mirror-image of the reader except that identifying portions corresponding to the receiving portions are insulated from only one of two coupling elements. Positive and negative pulses applied, respectively, to the two transmitting rings biased a CMOS shift register positively to either a 1 or 0 condition. The output of the CMOS may be read as an indication of the label.

  7. Capacitive label reader

    DOE Patents [OSTI]

    Arlowe, H.D.

    1985-11-12

    A capacitive label reader includes an outer ring transmitting portion, an inner ring transmitting portion, and a plurality of insulated receiving portions. A label is the mirror-image of the reader except that identifying portions corresponding to the receiving portions are insulated from only one of two coupling elements. Positive and negative pulses applied, respectively, to the two transmitting rings biased a CMOS shift register positively to either a 1 or 0 condition. The output of the CMOS may be read as an indication of the label. 5 figs.

  8. GETEM Manuals and Revision Notes

    Energy.gov [DOE]

    Please refer to these manuals and revision notes prior to downloading and running the Geothermal Electricity Technology Evaluation Model (GETEM). Because this is a beta version, you are urged to...

  9. OpenEI Community - notes

    Open Energy Information (Open El) [EERE & EIA]

    more

    http:en.openei.orgcommunityblognotes-callcomments notes Linked Open Data Workshop in Washington, D.C. Fri, 28 Sep 2012 00:57:30 +0000 Jweers 521 at...

  10. Notes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Accomodations at Argonne The Argonne contact person for the NUG Meeting is Mike Minkoff of the Mathematics and Computer Science Division. His phone number is (630) 252-7234. Last ...

  11. Notes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    topic of discussion was the issue of the processing capabilities of the PVP cluster. ... for its general users to take some of the load from the MPP andor the PVP platforms. ...

  12. Notes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    these lectures will be provided via RealPlayer. Users of Windows- or Macintosh-based computers will be able to see and hear the presentation by way of the following procedures. 1....

  13. Topic A Note: Includes STEPS Subtopic

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Topic A Note: Includes STEPS Subtopic 33 Total Projects Developing and Enhancing Workforce Training Programs...

  14. Map labeling and its generalizations

    SciTech Connect (OSTI)

    Doddi, S. |; Marathe, M.V.; Mirzaian, A.; Moret, B.M.E.; Zhu, B. |

    1997-01-01

    Map labeling is of fundamental importance in cartography and geographical information systems and is one of the areas targeted for research by the ACM Computational Geometry Impact Task Force. Previous work on map labeling has focused on the problem of placing maximal uniform, axis-aligned, disjoint rectangles on the plane so that each point feature to be labeled lies at the corner of one rectangle. Here, we consider a number of variants of the map labeling problem. We obtain three general types of results. First, we devise constant-factor polynomial-time-approximation algorithms for labeling point features by rectangular labels, where the feature may lie anywhere on the boundary of its label region and where labeling rectangles may be placed in any orientation. These results generalize to the case of elliptical labels. Secondly, we consider the problem of labeling a map consisting of disjoint rectilinear fine segments. We obtain constant-factor polynomial-time approximation algorithms for the general problem and an optimal algorithm for the special case where all segments are horizontal. Finally, we formulate a bicriteria version of the map-labeling problem and provide bicriteria polynomial- time approximation schemes for a number of such problems.

  15. Company Level Imports Explanatory Notes

    Gasoline and Diesel Fuel Update

    Company Level Imports Explanatory Notes Notice: Ongoing analysis of imports data to the Energy Information Administration reveals that some imports are not correctly reported on Form EIA-814 "Monthly Imports Report". Contact with the companies provides sufficient information for EIA to include these imports in the data even though they have not provided complete reports on Form EIA-814. Estimates are included in aggregate data, but the estimates are not included in the file of

  16. Lecture notes for criticality safety

    SciTech Connect (OSTI)

    Fullwood, R.

    1992-03-01

    These lecture notes for criticality safety are prepared for the training of Department of Energy supervisory, project management, and administrative staff. Technical training and basic mathematics are assumed. The notes are designed for a two-day course, taught by two lecturers. Video tapes may be used at the options of the instructors. The notes provide all the materials that are necessary but outside reading will assist in the fullest understanding. The course begins with a nuclear physics overview. The reader is led from the macroscopic world into the microscopic world of atoms and the elementary particles that constitute atoms. The particles, their masses and sizes and properties associated with radioactive decay and fission are introduced along with Einstein's mass-energy equivalence. Radioactive decay, nuclear reactions, radiation penetration, shielding and health-effects are discussed to understand protection in case of a criticality accident. Fission, the fission products, particles and energy released are presented to appreciate the dangers of criticality. Nuclear cross sections are introduced to understand the effectiveness of slow neutrons to produce fission. Chain reactors are presented as an economy; effective use of the neutrons from fission leads to more fission resulting in a power reactor or a criticality excursion. The six-factor formula is presented for managing the neutron budget. This leads to concepts of material and geometric buckling which are used in simple calculations to assure safety from criticality. Experimental measurements and computer code calculations of criticality are discussed. To emphasize the reality, historical criticality accidents are presented in a table with major ones discussed to provide lessons-learned. Finally, standards, NRC guides and regulations, and DOE orders relating to criticality protection are presented.

  17. Manhattan Project: A Note on Sources

    Office of Scientific and Technical Information (OSTI)

    A NOTE ON SOURCES Resources > Note on Sources The text for this web site is a combination of original material and adaptations from previous publications of the Department of ...

  18. Manhattan Project: A Note on Sources

    Office of Scientific and Technical Information (OSTI)

    A NOTE ON SOURCES Resources > Note on Sources The text for this web site is a combination ... To the best of our knowledge, all text and images on this web site are in the public ...

  19. Meeting Summary Notes | Department of Energy

    Office of Environmental Management (EM)

    Department of Energy Notes re NOI for Convention on Supplementary Compensation Meeting Notes re NOI for Convention on Supplementary Compensation notes from meeting on Convention on Supplementary Compensation Meeting Notes re NOI for Convention on Supplementary Compensation (45.83 KB) More Documents & Publications Convention on Supplementary Compensation for Nuclear Damage Contingent Cost Allocation Public comment re Convention on Supplementary Compensation on Nuclear Damage Contingent

  20. EM QA Working Group September 2011 Notes

    Energy.gov [DOE]

    Meeting minutes and notes from the EM QA Working Group video conference meeting held in September 2011.

  1. DOE Challenge Home Label Methodology

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    ... The label presents a comparison of minimally compliant homes. ComfortQuiet This category focuses on thermal comfort measures, construction details which dampen sound transmission, ...

  2. Labeled Cocaine Analogs

    DOE Patents [OSTI]

    Goodman, Mark M.; Shi, Bing Zhi; Keil, Robert N.

    1999-03-30

    Novel methods for positron emission tomography or single photon emission spectroscopy using tracer compounds having the structure: ##STR1## where X in .beta. configuration is phenyl, naphthyl; 2,3 or 4-iodophenyl; 2,3 or 4-(trimethylsilyl)phenyl; 3,4,5 or 6-iodonaphthyl; 3,4,5 or 6-(trimethylsilyl)naphthyl; 2,3 or 4-(trialkylstannyl)phenyl; or 3,4,5 or 6-(trialkylstannyl)napthyl Y in .beta. configuration is 2-fluoroethoxy, 3-fluoropropoxy, 4-fluorobutoxy, 2-fluorocyclopropoxy, 2 or 3-fluorocyclobutoxy, R,S 1'-fluoroisopropoxy, R 1'-fluoroisopropoxy, S 1'-fluoroisopropoxy, 1',3'-difluoroisopropoxy, R,S 1'-fluoroisobutoxy, R 1'-fluoroisobutoxy, S 1'-fluoroisobutoxy, R,S 4'-fluoroisobutoxy, R 4'-fluoroisobutoxy, S 4'-fluoroisobutoxy, or 1',1'-di(fluoromethyl)isobutoxy, The compounds bind dopamine transporter protein and can be labeled with .sup.18 F or .sup.123 I for imaging.

  3. Guidelines for Supplier, Vendor Shows

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Guidelines for Supplier, Vendor Shows Guidelines for SupplierVendor or Professional Local Trade FairsShows As a premier national research and development laboratory, LANL seeks...

  4. Labeled Cocaine Analogs

    DOE Patents [OSTI]

    Goodman, Mark M.; Shi, Bing Zhi; Keil, Robert N.

    1999-01-26

    Novel compounds having the structure: ##STR1## where X in .beta. configuration is phenyl, naphthyl; 2,3 or 4-iodophenyl; 2,3 or 4-(trimethylsilyl)phenyl; 3,4,5 or 6-iodonaphthyl; 3,4,5 or 6-(trimethylsilyl)naphthyl; 2,3 or 4-(trialkylstannyl)phenyl; or 3,4,5 or 6-(trialkylstannyl)naphthyl Y in .beta. configuration is Y.sub.1 or Y.sub.2, where Y.sub.1 is 2-fluoroethoxy, 3-fluoropropoxy, 4-fluorobutoxy, 2-fluorocyclopropoxy, 2 or 3-fluorocyclobutoxy, R,S 1'-fluoroisopropoxy, R 1'-fluoroisopropoxy, S 1'-fluoroisopropoxy, 1',3'-difluoroisopropoxy, R,S 1'-fluoroisobutoxy, R 1'-fluoroisobutoxy, S 1'-fluoroisobutoxy, R,S 4'-fluoroisobutoxy, R 4'-fluoroisobutoxy, S 4'-fluoroisobutoxy, or 1',1'-di(fluoromethyl)isobutoxy, and Y.sub.2 is 2-methanesulfonyloxy ethoxy, 3-methanesulfonyloxy propoxy, 4-methanesulfonyloxy butoxy, 2-methanesulfonyloxy cyclopropoxy, 2 or 3-methanesulfonyloxy cyclobutoxy, 1'methanesulfonyloxy isopropoxy, 1'-fluoro, 3'-methanesulfonyloxy isopropoxy, 1'-methanesulfonyloxy, 3'-fluoro isopropoxy, 1'-methanesulfonyloxy isobutoxy, or 4'-methanesulfonyloxy isobutoxy bind dopamine transporter protein and can be labeled with .sup.18 F or .sup.123 I for imaging.

  5. Synthesis Of Labeled Metabolites

    DOE Patents [OSTI]

    Martinez, Rodolfo A.; Silks, III, Louis A.; Unkefer, Clifford J.; Atcher, Robert

    2004-03-23

    The present invention is directed to labeled compounds, for example, isotopically enriched mustard gas metabolites including: [1,1',2,2'-.sup.13 C.sub.4 ]ethane, 1,1'-sulfonylbis[2-(methylthio); [1,1',2,2'-.sup.13 C.sub.4 ]ethane, 1-[[2-(methylsulfinyl)ethyl]sulfonyl]-2-(methylthio); [1,1',2,2'-.sup.13 C.sub.4 ]ethane, 1,1'-sulfonylbis[2-(methylsulfinyl)]; and, 2,2'-sulfinylbis([1,2-.sup.13 C.sub.2 ]ethanol of the general formula ##STR1## where Q.sup.1 is selected from the group consisting of sulfide (--S--), sulfone (--S(O)--), sulfoxide (--S(O.sub.2)--) and oxide (--O--), at least one C* is .sup.13 C, X is selected from the group consisting of hydrogen and deuterium, and Z is selected from the group consisting of hydroxide (--OH), and --Q.sup.2 --R where Q.sup.2 is selected from the group consisting of sulfide (--S--), sulfone(--S(O)--), sulfoxide (--S(O.sub.2)--) and oxide (--O--), and R is selected from the group consisting of hydrogen, a C.sub.1 to C.sub.4 lower alkyl, and amino acid moieties, with the proviso that when Z is a hydroxide and Q.sup.1 is a sulfide, then at least one X is deuterium.

  6. Consumer Electronics Show 2013 Highlights Sustainable Energy...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    The Octa processor for tablets and smartphones was noted by Samsung's CEO Stephen Woo to be more powerful without sacrificing efficiency. Samsung also won four awards in the ...

  7. Table Definitions, Sources, and Explanatory Notes

    Gasoline and Diesel Fuel Update

    Hydrogen The lightest of all gases, occurring chiefly in combination with oxygen in water; ... Background, Survey Methodology and Statistical Details . Explanatory Notes Hydrogen ...

  8. EM QA Working Group September 2011 Notes

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    suspectcounterfeit items, software QA, and corrective actions? Bob also noted that we need to be diligent in the understanding and use of the metrics to avoid potential issues ...

  9. A note on entropic force and brane cosmology

    SciTech Connect (OSTI)

    Ling, Yi; Wu, Jian-Pin E-mail: jianpinwu@yahoo.com.cn

    2010-08-01

    Recently Verlinde proposed that gravity is an entropic force caused by information changes when a material body moves away from the holographic screen. In this note we apply this argument to brane cosmology, and show that the cosmological equation can be derived from this holographic scenario.

  10. Backstage at the Daily Show

    Energy.gov [DOE]

    Backstage footage from Secretary Chu's appearance on the Daily Show where he discuses the green room candy dish and possible lighting considerations.

  11. Positron emitter labeled enzyme inhibitors

    DOE Patents [OSTI]

    Fowler, Joanna S.; MacGregor, Robert R.; Wolf, Alfred P.; Langstrom, Bengt

    1990-01-01

    This invention involves a new strategy for imaging and mapping enzyme activity in the living human and animal body using positron emitter-labeled suicide enzyme inactivators or inhibitors which become covalently bound to the enzyme as a result of enzymatic catalysis. Two such suicide inactivators for monoamine oxidase have been labeled with carbon-11 and used to map the enzyme subtypes in the living human and animal body using PET. By using positron emission tomography to image the distribution of radioactivity produced by the body penetrating radiation emitted by carbon-11, a map of functionally active monoamine oxidase activity is obtained. Clorgyline and L-deprenyl are suicide enzyme inhibitors and irreversibly inhibit monoamine oxidase. When these inhibitors are labeled with carbon-11 they provide selective probes for monoamine oxidase localization and reactivity in vivo using positron emission tomography.

  12. Positron emitter labeled enzyme inhibitors

    DOE Patents [OSTI]

    Fowler, J.S.; MacGregor, R.R.; Wolf, A.P.

    1987-05-22

    This invention involved a new strategy for imaging and mapping enzyme activity in the living human and animal body using positron emitter-labeled suicide enzyme inactivators or inhibitors which become covalently bound to the enzyme as a result of enzymatic catalysis. Two such suicide in activators for monoamine oxidase have been labeled with carbon-11 and used to map the enzyme subtypes in the living human and animal body using PET. By using positron emission tomography to image the distribution of radioactivity produced by the body penetrating radiation emitted by carbon-11, a map of functionally active monoamine oxidase activity is obtained. Clorgyline and L-deprenyl are suicide enzyme inhibitors and irreversibly inhibit monoamine oxidase. When these inhibitors are labeled with carbon-11 they provide selective probes for monoamine oxidase localization and reactivity in vivo using positron emission tomography. 2 figs.

  13. ShowMe3D

    Energy Science and Technology Software Center (OSTI)

    2012-01-05

    ShowMe3D is a data visualization graphical user interface specifically designed for use with hyperspectral image obtained from the Hyperspectral Confocal Microscope. The program allows the user to select and display any single image from a three dimensional hyperspectral image stack. By moving a slider control, the user can easily move between images of the stack. The user can zoom into any region of the image. The user can select any pixel or region from themore » displayed image and display the fluorescence spectrum associated with that pixel or region. The user can define up to 3 spectral filters to apply to the hyperspectral image and view the image as it would appear from a filter-based confocal microscope. The user can also obtain statistics such as intensity average and variance from selected regions.« less

  14. ShowMe3D

    SciTech Connect (OSTI)

    Sinclair, Michael B

    2012-01-05

    ShowMe3D is a data visualization graphical user interface specifically designed for use with hyperspectral image obtained from the Hyperspectral Confocal Microscope. The program allows the user to select and display any single image from a three dimensional hyperspectral image stack. By moving a slider control, the user can easily move between images of the stack. The user can zoom into any region of the image. The user can select any pixel or region from the displayed image and display the fluorescence spectrum associated with that pixel or region. The user can define up to 3 spectral filters to apply to the hyperspectral image and view the image as it would appear from a filter-based confocal microscope. The user can also obtain statistics such as intensity average and variance from selected regions.

  15. Table Definitions, Sources, and Explanatory Notes

    Gasoline and Diesel Fuel Update

    Note: The conversion factor for asphalt is 5.5 barrels per short ton. Barrel A unit of volume equal to 42 U.S. gallons. Biomass-Based Diesel Fuel Biodiesel and other renewable ...

  16. Coal Working Group - AEO2017 Summary Notes

    U.S. Energy Information Administration (EIA) (indexed site)

    AEO2017 MODELING ASSUMPTIONS AND NOTE INPUTS ARE SUBJECT TO CHANGE. 1 September 7, 2016 MEMORANDUM TO: Dr. Ian Mead Assistant Administrator for Energy Analysis Jim Diefenderfer Director, Office of Electricity, Coal, Nuclear, and Renewables Analysis FROM: Coal and Uranium Analysis Team SUBJECT: Notes from the AEO2017 1 st Coal Working Group held on August 31, 2016 Attendees (62) *Indicates participation via WebEx. In an effort to solicit feedback each year, the Coal and Uranium Analysis Team

  17. Overview of Existing Home Energy Labels

    Office of Energy Efficiency and Renewable Energy (EERE)

    This analysis looks at home energy labeling programs around the world and highlights similarities and differences of various approaches.

  18. PIA - Savannah River Operations Office Lotus Domino/Notes System...

    Energy.gov (indexed) [DOE]

    Lotus DominoNotes System PDF icon PIA - Savannah River Operations Office Lotus DominoNotes System More Documents & Publications PIA - DOE Savannah River Operations Office PRISM ...

  19. Notes on Newton-Krylov based Incompressible Flow Projection Solver...

    Office of Scientific and Technical Information (OSTI)

    Notes on Newton-Krylov based Incompressible Flow Projection Solver Citation Details In-Document Search Title: Notes on Newton-Krylov based Incompressible Flow Projection Solver The ...

  20. Notes on Newton-Krylov based Incompressible Flow Projection Solver...

    Office of Scientific and Technical Information (OSTI)

    Notes on Newton-Krylov based Incompressible Flow Projection Solver Citation Details In-Document Search Title: Notes on Newton-Krylov based Incompressible Flow Projection Solver ...

  1. Note: On the wavelength dependence of the intensity calibration...

    Office of Scientific and Technical Information (OSTI)

    Note: On the wavelength dependence of the intensity calibration factor of extreme ... Title: Note: On the wavelength dependence of the intensity calibration factor of extreme ...

  2. Note: Coherent resonances observed in the dissociative electron...

    Office of Scientific and Technical Information (OSTI)

    Note: Coherent resonances observed in the dissociative electron attachment to carbon monoxide Citation Details In-Document Search Title: Note: Coherent resonances observed in the ...

  3. Preparation of Radiopharmaceuticals Labeled with Metal Radionuclides

    SciTech Connect (OSTI)

    Welch, M.J.

    2012-02-16

    The overall goal of this project was to develop methods for the production of metal-based radionuclides, to develop metal-based radiopharmaceuticals and in a limited number of cases, to translate these agents to the clinical situation. Initial work concentrated on the application of the radionuclides of Cu, Cu-60, Cu-61 and Cu-64, as well as application of Ga-68 radiopharmaceuticals. Initially Cu-64 was produced at the Missouri University Research Reactor and experiments carried out at Washington University. A limited number of studies were carried out utilizing Cu-62, a generator produced radionuclide produced by Mallinckrodt Inc. (now Covidien). In these studies, copper-62-labeled pyruvaldehyde Bis(N{sup 4}-methylthiosemicarbazonato)-copper(II) was studied as an agent for cerebral myocardial perfusion. A remote system for the production of this radiopharmaceutical was developed and a limited number of patient studies carried out with this agent. Various other copper radiopharmaceuticals were investigated, these included copper labeled blood imaging agents as well as Cu-64 labeled antibodies. Cu-64 labeled antibodies targeting colon cancer were translated to the human situation. Cu-64 was also used to label peptides (Cu-64 octriatide) and this is one of the first applications of a peptide radiolabeled with a positron emitting metal radionuclide. Investigations were then pursued on the preparation of the copper radionuclides on a small biomedical cyclotron. A system for the production of high specific activity Cu-64 was developed and initially the Cu-64 was utilized to study the hypoxic imaging agent Cu-64 ATSM. Utilizing the same target system, other positron emitting metal radionuclides were produced, these were Y-86 and Ga-66. Radiopharmaceuticals were labeled utilizing both of these radionuclides. Many studies were carried out in animal models on the uptake of Cu-ATSM in hypoxic tissue. The hypothesis is that Cu-ATSM retention in vivo is dependent upon the

  4. Application Note: Power Grid Modeling With Xyce.

    SciTech Connect (OSTI)

    Sholander, Peter E.

    2015-06-01

    This application note describes how to model steady-state power flows and transient events in electric power grids with the SPICE-compatible Xyce TM Parallel Electronic Simulator developed at Sandia National Labs. This application notes provides a brief tutorial on the basic devices (branches, bus shunts, transformers and generators) found in power grids. The focus is on the features supported and assumptions made by the Xyce models for power grid elements. It then provides a detailed explanation, including working Xyce netlists, for simulating some simple power grid examples such as the IEEE 14-bus test case.

  5. RAP Meeting Transcribed Flip Chart Notes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Flip Chart Notes February 15, 2012 Site-wide Permit Workshop May 3 1. Have "post-workshop" session to discuss HAB next steps 2. Recommend Ecology sponsors & facilitates Workshop - Ecology captures notes, but HAB members track issues of concern, too. 3. Web-ex for public when it fits 4. Pre-workshop meeting with HAB issue leaders (potential speakers) Page 1 300 Area HAB next steps... IM & Pam 1. Issue managers meet to review potential issues for HAB/committees 2. Bring back to

  6. Xyce parallel electronic simulator release notes.

    SciTech Connect (OSTI)

    Keiter, Eric Richard; Hoekstra, Robert John; Mei, Ting; Russo, Thomas V.; Schiek, Richard Louis; Thornquist, Heidi K.; Rankin, Eric Lamont; Coffey, Todd Stirling; Pawlowski, Roger Patrick; Santarelli, Keith R.

    2010-05-01

    The Xyce Parallel Electronic Simulator has been written to support, in a rigorous manner, the simulation needs of the Sandia National Laboratories electrical designers. Specific requirements include, among others, the ability to solve extremely large circuit problems by supporting large-scale parallel computing platforms, improved numerical performance and object-oriented code design and implementation. The Xyce release notes describe: Hardware and software requirements New features and enhancements Any defects fixed since the last release Current known defects and defect workarounds For up-to-date information not available at the time these notes were produced, please visit the Xyce web page at http://www.cs.sandia.gov/xyce.

  7. Notes on beam dynamics in linear accelerators

    SciTech Connect (OSTI)

    Gluckstern, R.L.

    1980-09-01

    A collection of notes, on various aspects of beam dynamics in linear accelerators, which were produced by the author during five years (1975 to 1980) of consultation for the LASL Accelerator Technology (AT) Division and Medium-Energy Physics (MP) Division is presented.

  8. Hemoglobin Labeled by Radioactive Lysine

    DOE R&D Accomplishments [OSTI]

    Bale, W. F.; Yuile, C. L.; DeLaVergne, L.; Miller, L. L.; Whipple, G. H.

    1949-12-08

    This paper reports on the utilization of tagged epsilon carbon of DL-lysine by a dog both anemic and hypoproteinemic due to repeated bleeding plus a diet low in protein. The experiment extended over period of 234 days, a time sufficient to indicate an erythrocyte life span of at least 115 days based upon the rate of replacement of labeled red cell proteins. The proteins of broken down red cells seem not to be used with any great preference for the synthesis of new hemoglobin.

  9. LLW notes, Vol. 11, No. 2

    SciTech Connect (OSTI)

    1996-03-01

    `LLW Notes` is distributed by Afton Associates, Inc. to Low-Level Radioactive Waste Forum Participants and other state, and compact officials identified by those Participants to receive LLW Notes. The Low-Level Radioactive Waste Forum (LLW Forum) is an association of state and compact representatives, appointed by governors and compact commissions, established to facilitate state and compact implementation of the Low-Level Radioactive Waste Policy Act of 1980 and the Low-Level Radioactive Waste Policy amendments Act of 1985 and to promote the objectives of low-level radioactive waste regional compacts. The LLW Forum provides an opportunity for state and compact officials to share information with one another and to exchange views with officials of federal agencies and other interested parties.

  10. LLW notes. Volume 11, No.8

    SciTech Connect (OSTI)

    1996-12-01

    `LLW Notes` is distributed by Afton Associates, Inc. to Low-Level Radioactive Waste Forum Participants and other state, and compact officials identified by those Participants to receive `LLW Notes`. The Low-Level Radioactive Waste Forum (LLW Forum) is an association of state and compact representatives, appointed by governors and compact commissions, established to facilitate state and compact implementation of the Low-Level Radioactive Waste Policy Act of 1980 and the Low-Level Radioactive Waste Policy Amendments Act of 1985 and to promote the objectives of low-level radioactive waste regional compacts. The LLW Forum provides an opportunity for state and compact officials to share information with one another and to exchange views with officials of federal agencies and other interested parties.

  11. Table Definitions, Sources, and Explanatory Notes

    Gasoline and Diesel Fuel Update

    Receipts by Pipeline, Tanker, and Barge Between PAD Districts Definitions Key Terms Definition Asphalt A dark-brown-to-black cement-like material containing bitumens as the predominant constituent obtained by petroleum processing; used primarily for road construction. It includes crude asphalt as well as the following finished products: cements, fluxes, the asphalt content of emulsions (exclusive of water), and petroleum distillates blended with asphalt to make cutback asphalts. Note: The

  12. labNotes | netl.doe.gov

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    LabNotes NETL Validates Innovative Spectrometry Technique libs-PIC.JPG Graphic representation of in situ measurements of calcium carbonate dissolution under rising CO2 pressure using underwater laser-induced breakdown spectroscopy. Image used as the front cover for the Journal of Analytical Atomic Spectrometry's July 2016 issue. An article highlighting NETL's research into the use of laser spectrometry to collect data vital to ensuring the efficacy and safety of geologic carbon storage sites was

  13. Table Definitions, Sources, and Explanatory Notes

    Gasoline and Diesel Fuel Update

    Shale Gas Production Definitions Key Terms Definition Shale Gas Natural gas produced from organic (black) shale formations. For definitions of related energy terms, refer to the EIA Energy Glossary. Sources Energy Information Administration, Office of Oil and Gas Explanatory Notes Shale Gas production data collected in conjunction with proved reserves data on Form EIA-23 are unofficial. Official Shale Gas production data from Form EIA-895 can be found in Natural Gas Gross Withdrawals and

  14. HSEP Committee Meeting - Transcribed Flipchart Notes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Flipchart Notes August 8, 2013 Safety Culture Next Steps 1. Continue to get periodic briefings from SCIPT - progress on action items, contractor engagement, etc. 2. Get update on HSS review Page 1 DS Tanks/Flammable Gas - Next Steps 1. Update after DOE report on tank flow rate monitoring is available (Jan/Feb) 2. Tom w/follow up with concerns about pressurization alarms Page 2 Emergency Preparedness/Response: Input - Strategies for Awareness 1. Use real examples when trying to increase

  15. Labeled nucleotide phosphate (NP) probes

    DOE Patents [OSTI]

    Korlach, Jonas; Webb, Watt W.; Levene, Michael; Turner, Stephen; Craighead, Harold G.; Foquet, Mathieu

    2009-02-03

    The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined.

  16. Table Definitions, Sources, and Explanatory Notes

    Gasoline and Diesel Fuel Update

    API Gravity Definitions Key Terms Definition API Gravity An arbitrary scale expressing the gravity or density of liquid petroleum products. The measuring scale is calibrated in terms of degrees API; it is calculated as follows: Degrees API = (141.5 / (sp. gr. 60ºF / 60ºF)) - 131.5 The higher the API gravity, the lighter the compound. Light crudes generally exceed 38 degrees API and heavy crudes are commonly labeled as all crudes with an API gravity of 22 degrees or below. Intermediate crudes

  17. eNews Note of Appreciation

    National Nuclear Security Administration (NNSA)

    3 Issue 25 ASC eNews Quarterly Newsletter September 2013 A Note of Appreciation Reeta Garber The ASC Program would like to recognize Reeta Garber for her leadership in designing and developing programmatic communications tools and activities and to wish her the very best as she retires (again) to begin a new phase in her life. Since 1998 Reeta has supported the ASC Program as an important member of the core team responsible for spreading the word about DOE/NNSA laboratory and Federal efforts in

  18. Meeting Notes re NOI for Convention on Supplementary Compensation |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Notes re NOI for Convention on Supplementary Compensation Meeting Notes re NOI for Convention on Supplementary Compensation notes from meeting on Convention on Supplementary Compensation Meeting Notes re NOI for Convention on Supplementary Compensation (45.83 KB) More Documents & Publications Convention on Supplementary Compensation for Nuclear Damage Contingent Cost Allocation Public comment re Convention on Supplementary Compensation on Nuclear Damage Contingent

  19. DOE Durability Working Group October 2011 Meeting Notes | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Energy 1 Meeting Notes DOE Durability Working Group October 2011 Meeting Notes Meeting notes from the Fall 2011 Durability Working Group (DWG) Meeting sponsored by the U.S. Department of Energy (DOE) Fuel Cell Technologies Program. Notes also include a summary of progress on action items from the Spring 2011 DWG meeting. durability_working_group_minutes_oct_2011.pdf (54.58 KB) More Documents & Publications DOE Durability Working Group October 2010 Meeting Minutes DOE Durability Working

  20. The MicroBooNE Experiment - Public Notes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Public Notes Page Back to the Publications Page 7/4/16 MICROBOONE-NOTE-1019-PUB Convolutional Neural Networks Applied to Neutrino Events in a Liquid Argon Time Projection Chamber 7/4/16 MICROBOONE-NOTE-1017-PUB A Method to Extract the Charge Distribution Arriving at the TPC Wire Planes in MicroBooNE 7/4/16 MICROBOONE-NOTE-1016-PUB Noise Characterization and Filtering in the MicroBooNE TPC 7/4/16 MICROBOONE-NOTE-1015-PUB The Pandora multi-algorithm approach to automated pattern recognition in LAr

  1. The art and science of magnet design: Selected notes of Klaus Halbach. Volume 2

    SciTech Connect (OSTI)

    1995-02-01

    This volume contains a compilation of 57 notes written by Dr. Klaus Halbach selected from his collection of over 1650 such documents. It provides an historic snapshot of the evolution of magnet technology and related fields as the notes range from as early as 1965 to the present, and is intended to show the breadth of Dr. Halbach`s interest and ability that have long been an inspiration to his many friends and colleagues. As Halbach is an experimental physicist whose scientific interests span many areas, and who does his most innovative work with pencil and paper rather than at the workbench or with a computer, the vast majority of the notes in this volume were handwritten and their content varies greatly--some reflect original work or work for a specific project, while others are mere clarifications of mathematical calculations or design specifications. As the authors converted the notes to electronic form, some were superficially edited and corrected, while others were extensively re-written to reflect current knowledge and notation. The notes are organized under five categories which reflect their primary content: Beam Position Monitors, (bpm), Current Sheet Electron Magnets (csem), Magnet Theory, (thry), Undulators and Wigglers (u-w), and Miscellaneous (misc). Within the category, they are presented chronologically starting from the most recent note and working backwards in time.

  2. Nanomaterial Labels in Electrochemical Immunosensors and Immunoassays

    SciTech Connect (OSTI)

    Liu, Guodong; Lin, Yuehe

    2007-12-15

    This article reviews recent advances in nanomaterial labels in electrochemical immunosensors and immunoassays. Various nanomaterial labels are discussed, including colloidal gold/silver, semiconductor nanoparticles, and markers loaded nanocarriers (carbon nanotubes, apoferritin, silica nanoparticles, and liposome beads). The enormous signal enhancement associated with the use of nanomaterial labels and with the formation of nanomaterialantibody-antigen assemblies provides the basis for ultrasensitive electrochemical detection of disease-related protein biomarkers, biothreat agents, or infectious agents. In general, all endeavors cited here are geared to achieve one or more of the following goals: signal amplification by several orders of magnitude, lower detection limits, and detecting multiple targets.

  3. ENERGY STAR Labeled Buildings and Plants | Open Energy Information

    Open Energy Information (Open El) [EERE & EIA]

    STAR Labeled Buildings and Plants Jump to: navigation, search Name ENERGY STAR Labeled Buildings and Plants Data Format Excel Spreadsheet Geographic Scope United States TODO:...

  4. Energy Efficiency Labeling System & its Development in China...

    Energy Savers

    Energy Efficiency Labeling System & its Development in China Energy Efficiency Labeling System & its Development in China Information about the regulations, formats, objectives, ...

  5. Label-invariant Mesh Quality Metrics. (Conference) | SciTech...

    Office of Scientific and Technical Information (OSTI)

    Label-invariant Mesh Quality Metrics. Citation Details In-Document Search Title: Label-invariant Mesh Quality Metrics. Abstract not provided. Authors: Knupp, Patrick Publication ...

  6. Show Me Ethanol LLC | Open Energy Information

    Open Energy Information (Open El) [EERE & EIA]

    Show Me Ethanol LLC Jump to: navigation, search Name: Show Me Ethanol, LLC Place: Carrollton, Missouri Zip: 64633 Product: Developing an ethanol project in Carrollton, Missouri....

  7. Detroit Auto Show 2012 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Detroit Auto Show 2012 Detroit Auto Show 2012 Addthis 1 of 10 Energy Secretary Steven Chu with Chrysler Chief Executive Sergio Marchionne. Image: Hantz Leger (Energy Department ...

  8. Radionuclide labeled lymphocytes for therapeutic use

    DOE Patents [OSTI]

    Srivastava, Suresh C.; Fawwaz, Rashid A.; Richards, Powell

    1985-01-01

    Lymphocytes labelled with .beta.-emitting radionuclides are therapeutically useful, particularly for lymphoid ablation. They are prepared by incubation of the lymphocytes with the selected radionuclide-oxine complex.

  9. Radionuclide labeled lymphocytes for therapeutic use

    DOE Patents [OSTI]

    Srivastava, S.C.; Fawwaz, R.A.; Richards, P.

    1983-05-03

    Lymphocytes labelled with ..beta..-emitting radionuclides are therapeutically useful, particularly for lymphoid ablation. They are prepared by incubation of the lymphocytes with the selected radionuclide-oxine complex.

  10. Subsea completion data show steady activity levels

    SciTech Connect (OSTI)

    Mohr, H.O. )

    1993-02-01

    Review of subsea completion statistics indicates 45 installations during 1992 - one more than during 1991. The 45 installations are still considerably less than the all-time high of 66 installations in 1985. Petrobras continues to install three times as many subsea completions as Shell, the next most active user. However, as in the past three years, the overall-lower number of installations last year was due to reduced applications by Petrobras. During 1991, that company installed 10 subsea completions, whereas during 1988, for example, it completed 37 installations. It should be noted that reduced activity by petrobras reflects problems with financing and general activity, rather than a lack of confidence in subsea completions. The number of future subsea completions identified for installation during the next 10 years is 1,144 - some 10% more than the 1,014 identified at the end of 1991. The present planned installation figure is an all-time high; the next highest number of installations identified was 1,083 at the end of 1989. These and other statistics are presented in 10 tables. A brief analysis of each is included.

  11. Multiple tag labeling method for DNA sequencing

    DOE Patents [OSTI]

    Mathies, R.A.; Huang, X.C.; Quesada, M.A.

    1995-07-25

    A DNA sequencing method is described which uses single lane or channel electrophoresis. Sequencing fragments are separated in the lane and detected using a laser-excited, confocal fluorescence scanner. Each set of DNA sequencing fragments is separated in the same lane and then distinguished using a binary coding scheme employing only two different fluorescent labels. Also described is a method of using radioisotope labels. 5 figs.

  12. Multiple tag labeling method for DNA sequencing

    DOE Patents [OSTI]

    Mathies, Richard A.; Huang, Xiaohua C.; Quesada, Mark A.

    1995-01-01

    A DNA sequencing method described which uses single lane or channel electrophoresis. Sequencing fragments are separated in said lane and detected using a laser-excited, confocal fluorescence scanner. Each set of DNA sequencing fragments is separated in the same lane and then distinguished using a binary coding scheme employing only two different fluorescent labels. Also described is a method of using radio-isotope labels.

  13. The Paris Motor Show | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    The Paris Motor Show The Paris Motor Show October 4, 2010 - 9:39am Addthis David Sandalow at the Paris Auto Show | DOE photo David Sandalow at the Paris Auto Show | DOE photo David Sandalow David Sandalow Former Under Secretary of Energy (Acting) and Assistant Secretary for Policy & International Affairs At the Paris Motor Show today, electric cars are everywhere. Chevrolet is showing off the Volt, its plug-in hybrid due in U.S. showrooms this December. (Motown music blared as a Chevy rep

  14. California Homebuyers Find More Value in Energy-Efficient Labeled Homes |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy California Homebuyers Find More Value in Energy-Efficient Labeled Homes California Homebuyers Find More Value in Energy-Efficient Labeled Homes A photo of a house. During a time when many homeowners have seen their homes' values decrease, some encouraging data shows how investing in efficiency will boost resale value. Aside from the increased comfort and reduced utility bills that stem from home energy efficiency upgrades, homeowners who invest in energy-efficient

  15. BNL ALARA Center: ALARA Notes, No. 9

    SciTech Connect (OSTI)

    Khan, T.A.; Xie, J.W.; Beckman, M.C.

    1994-02-01

    This issue of the Brookhaven National Laboratory`s Alara Notes includes the agenda for the Third International Workshop on ALARA and specific instructions on the use of the on-line fax-on-demand service provided by BNL. Other topics included in this issue are: (1) A discussion of low-level discharges from Canadian nuclear plants, (2) Safety issues at French nuclear plants, (3) Acoustic emission as a means of leak detection, (4) Replacement of steam generators at Doel-3, Beaznau, and North Anna-1, (5) Remote handling equipment at Bruce, (6) EPRI`s low level waste program, (7) Radiation protection during concrete repairs at Savannah River, (8) Reactor vessel stud removal/repair at Comanche Peak-1, (9) Rework of reactor coolant pump motors, (10) Restoration of service water at North Anna-1 and -2, (11) Steam generator tubing problems at Mihama-1, (12) Full system decontamination at Indian Point-2, (13) Chemical decontamination at Browns Ferry-2, and (14) Inspection methodolody in France and Japan.

  16. Consortium for Energy Efficiency (CEE) Notes_ Clothes Dryer Test Procedure

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    | Department of Energy Consortium for Energy Efficiency (CEE) Notes_ Clothes Dryer Test Procedure Consortium for Energy Efficiency (CEE) Notes_ Clothes Dryer Test Procedure CEE and DOE staff discussed the importance of relying on the DOE test method as the sole metric for efficiency and energy use reporting. CEE_Notes_ClothesDryerTestProcedure_25Apr2016 (352.34 KB) More Documents & Publications 2015-03-23 Issuance: Energy Conservation Standards for Residential Clothes Dryers; Request for

  17. Workshop Notes from ""Compressed Natural Gas and Hydrogen Fuels...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Hydrogen Fuels: Lessons Learned for the Safe Deployment of Vehicles"" Workshop, December 10-11, 2009 Workshop Notes from ""Compressed Natural Gas and Hydrogen Fuels: Lessons ...

  18. West Flank Coso FORGE: well photos and notes

    SciTech Connect (OSTI)

    Doug Blankenship

    2015-12-21

    Photos and detailed down-hole lithology notes for wells CGEH-1 and 74-2 at the West Flank Coso, Ca FORGE location.

  19. State Energy Data System 2014 Consumption Technical Notes

    Annual Energy Outlook

    Consumption Technical Notes U.S. Energy Information Administration | State Energy Data 2014: Consumption 3 Purpose All of the estimates contained in the state energy consumption ...

  20. COLLOQUIUM - PLEASE NOTE SPECIAL DATE/TIME: The Magnetospheric...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    COLLOQUIUM - PLEASE NOTE SPECIAL DATETIME: The Magnetospheric MultiScale Mission Investigation of Magnetic Reconnection Professor Roy Torbert University of New Hampshire ...

  1. Structural and Evolutionary Analyses Show Unique Stabilization...

    Office of Scientific and Technical Information (OSTI)

    Title: Structural and Evolutionary Analyses Show Unique Stabilization Strategies in the Type IV Pili of Clostridium difficile Authors: Piepenbrink, Kurt H. ; Maldarelli, Grace A. ; ...

  2. Use of labeled primers for differential display

    SciTech Connect (OSTI)

    Paunesku, T.; Woloschak, G.E.

    1995-02-01

    The differential display of eukaryotic cDNAs using PCR allows for determination of mRNA species differentially expressed when comparing two similar cell populations. This procedure uses a (T){sub 12}XY oligonucleotide as the 3 ft primer and an arbitrary 8-10-mer as the 5 ft primer. Labeling occurs by inclusion of {alpha}[{sup 33}P]-dATP in the PCR reaction. Two artifacts caused by this approach are (1) random printing from dT present from affinity purification of PolyA+RNA and (2) hybridization of the arbitrary primer to template target sequences on both cDNA strands. In this work, we have developed an approach for both eliminating smearing and identifying nonspecific bands on sequencing gels. By separately using 5 ft-end-labeled (T){sub 12}XY and arbitrary primers to label bands and comparing two differential display patterns rather than including labeled nucleotides in the PCR reaction itself, we can detect only those products incorporating the M{sub 12}XY primer on the 3 ft ends and the arbitrary primer on 5 ft ends. Those bands that are generated randomly in the PCR reaction are readily detectable and can be ignored. If on the other hand, one is interested only in a diagnostic banding pattern for differential display, benefit can be derived from the simplicity of the pattern obtained when labeled (T){sub 12}XY is used.

  3. Deep Learning in Label-free Cell Classification

    DOE PAGES-Beta [OSTI]

    Chen, Claire Lifan; Mahjoubfar, Ata; Tai, Li-Chia; Blaby, Ian K.; Huang, Allen; Niazi, Kayvan Reza; Jalali, Bahram

    2016-03-15

    Label-free cell analysis is essential to personalized genomics, cancer diagnostics, and drug development as it avoids adverse effects of staining reagents on cellular viability and cell signaling. However, currently available label-free cell assays mostly rely only on a single feature and lack sufficient differentiation. Also, the sample size analyzed by these assays is limited due to their low throughput. Here, we integrate feature extraction and deep learning with high-throughput quantitative imaging enabled by photonic time stretch, achieving record high accuracy in label-free cell classification. Our system captures quantitative optical phase and intensity images and extracts multiple biophysical features of individualmore » cells. These biophysical measurements form a hyperdimensional feature space in which supervised learning is performed for cell classification. We compare various learning algorithms including artificial neural network, support vector machine, logistic regression, and a novel deep learning pipeline, which adopts global optimization of receiver operating characteristics. As a validation of the enhanced sensitivity and specificity of our system, we show classification of white blood T-cells against colon cancer cells, as well as lipid accumulating algal strains for biofuel production. In conclusion, this system opens up a new path to data-driven phenotypic diagnosis and better understanding of the heterogeneous gene expressions in cells.« less

  4. DOE Booth Presentations From Grainger Show 2015

    Energy.gov [DOE]

    DOE hosted its solid-state lighting informational booth February 16–18 at the annual Grainger Show in Orlando, FL. With over 17,000 attendees and over 750 exhibitors, the show gathered a wide range of Grainger customers—from universities to large hotel chains as well as Grainger team members to learn the latest about LED lighting.

  5. 2013 Washington Auto Show | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    3 Washington Auto Show 2013 Washington Auto Show Addthis 1 of 10 While at the Washington Auto Show, Energy Secretary Steven Chu visited Nissan to see the 2013 Leaf. | Photo courtesy of Sarah Gerrity, Energy Department. Date taken: 2013-01-31 13:50 2 of 10 The new Nissan Leaf is being built at the company's Smyrna, Tennessee, Vehicle Assembly Plant -- helping to cut the price of its electric vehicle. | Photo courtesy of Sarah Gerrity, Energy Department. Date taken: 2013-01-31 13:49 3 of 10 Energy

  6. 2016 Washington Auto Show | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Washington Auto Show 2016 Washington Auto Show Addthis 1 of 20 Energy Secretary Ernest Moniz sits in the driver's seat of the all-electric Chevrolet Bolt at the Washington Auto Show. When it debuts on the road later this year, the Bolt will offer drivers about 200 miles of electric range. Image: Simon Edelman, Energy Department Date taken: 2016-01-21 09:45 2 of 20 The 2016 next-generation Chevrolet Volt builds on the success of its previous version, which was the first plug-in hybrid electric

  7. Probes labelled with energy transfer coupled dyes

    DOE Patents [OSTI]

    Mathies, R.A.; Glazer, A.; Ju, J.

    1997-11-18

    Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids. 7 figs.

  8. International Builders' Show | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Builders' Show International Builders' Show February 14, 2008 - 11:29am Addthis Remarks as Prepared for Delivery by Secretary Bodman Thank you, Andy, and thank you all for being here. The world has reached an energy crossroads. Rising global energy demand and the need for more environmentally-responsible energy production and consumption have presented us with a number of global challenges that require global solutions. Every American has a role to play in meeting these challenges. And that's

  9. Gasoline price shows small increase (Short version)

    U.S. Energy Information Administration (EIA) (indexed site)

    shows small increase (Short version) The U.S. average retail price for regular gasoline rose to $3.32 a gallon on Monday. That's up 1.2 cents from a week ago, based on the weekly price survey by the U.S. Energy Information Administration.

  10. Gasoline price shows small increase (short version)

    U.S. Energy Information Administration (EIA) (indexed site)

    Short version) The U.S. average retail price for regular gasoline showed little movement from last week. Prices rose 4/10 of a cent to $3.30 a gallon on Monday, based on the weekly price survey by the U.S. Energy Information Administration.

  11. Geothermal Energy Featured on NBC's Today Show

    Energy.gov [DOE]

    In Iceland, there are five major geothermal power plants which produce about 26% (2006) of the country's electricity. In addition, geothermal heating meets the heating and hot water requirements for around 87% of the nation's buildings. As part of its "Ends of the Earth" series, NBC's Today Show presented a feature on the use of geothermal energy in Iceland.

  12. Tc-99m Labeled carrier for imaging

    DOE Patents [OSTI]

    Henze, Eberhard

    1984-01-01

    Novel radionuclide imaging agents, having particular application for lymphangiography are provided by non-covalently binding Tc-99m to a pharmaceutically acceptable cross-linked polysaccharide. Upon injection of the Tc-99m labeled polysaccharide into the blood stream, optimum contrast can be obtained within one hour.

  13. Microfluidic Radiometal Labeling Systems for Biomolecules

    SciTech Connect (OSTI)

    Reichert, D E; Kenis, P J. A.

    2011-12-29

    In a typical labeling procedure with radiometals, such as Cu-64 and Ga-68; a very large (~ 100-fold) excess of the non-radioactive reactant (precursor) is used to promote rapid and efficient incorporation of the radioisotope into the PET imaging agent. In order to achieve high specific activities, careful control of reaction conditions and extensive chromatographic purifications are required in order to separate the labeled compounds from the cold precursors. Here we propose a microfluidic approach to overcome these problems, and achieve high specific activities in a more convenient, semi-automated fashion and faster time frame. Microfluidic reactors, consisting of a network of micron-sized channels (typical dimensions in the range 10 - 300¼m), filters, separation columns, electrodes and reaction loops/chambers etched onto a solid substrate, are now emerging as an extremely useful technology for the intensification and miniaturization of chemical processes. The ability to manipulate, process and analyze reagent concentrations and reaction interfaces in both space and time within the channel network of a microreactor provides the fine level of reaction control that is desirable in PET radiochemistry practice. These factors can bring radiometal labeling, specifically the preparation of radio-labeled biomolecules such as antibodies, much closer to their theoretical maximum specific activities.

  14. Laser research shows promise for cancer treatment

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Cancer treatment Laser research shows promise for cancer treatment Scientists have observed for the first time how a laser penetrates dense, electron-rich plasma to generate ions. August 20, 2012 Sasi Palaniyappan, right, and Rahul Shah inside a target chamber where the TRIDENT short pulse laser is aimed at a very thin foil target. Sasi Palaniyappan, right, and Rahul Shah inside a target chamber where the TRIDENT short pulse laser is aimed at a very thin foil target. Contact Nancy Ambrosiano

  15. Gasoline price shows small increase (long version)

    U.S. Energy Information Administration (EIA) (indexed site)

    long version) The U.S. average retail price for regular gasoline showed little movement from last week. Prices rose 4/10 of a cent to $3.30 a gallon on Monday, based on the weekly price survey by the U.S. Energy Information Administration. Pump prices were highest in the New England States, at 3.52 a gallon, down 1/10 of a penny from a week ago. Prices were lowest at 2.87 a gallon in the Rocky Mountain States, with the biggest regional price drop at close to 7 cents.

  16. PLEASE NOTE THURSDAY DATE - COLLOQUIUM: Professor Ralph Roskies...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    May 23, 2013, 4:15pm to 5:30pm Colloquia MBG Auditorium PLEASE NOTE THURSDAY DATE - COLLOQUIUM: Professor Ralph Roskies - "Big Data at the Pittsburgh Supercomputing Center" ...

  17. Lumens and the Lighting Facts Label | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    It helps people buy the lightbulbs that are right for them. Like the helpful nutrition label on food products, the Lighting Facts label helps consumers understand what they are ...

  18. 99M-technetium labeled macroaggregated human serum albumin pharmaceutical

    DOE Patents [OSTI]

    Winchell, Harry S.; Barak, Morton; Van Fleet, III, Parmer

    1977-05-17

    A reagent comprising macroaggregated human serum albumin having dispersed therein particles of stannous tin and a method for instantly making a labeled pharmaceutical therefrom, are disclosed. The labeled pharmaceutical is utilized in organ imaging.

  19. CRAD, Equipment and Piping Labeling Assessment Plan | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Equipment and Piping Labeling Assessment Plan CRAD, Equipment and Piping Labeling Assessment Plan Performance Objective: To verify that facility equipment and piping are labeled in a manner such that facility personnel are able to positively identify equipment they operate. To ensure that an effective labeling program is in effect to reduce operator and maintenance errors from incorrect identification of equipment, to increase training effectiveness by tracing the actual facility system as

  20. An introduction to the National Tritium Labeling Facility

    SciTech Connect (OSTI)

    Dorsky, A.M.; Morimoto, H.; Saljoughian, M.; Williams, P.G.; Rapoport, H.

    1988-06-01

    The facilities and projects of the National Tritium Labeling Facility are described. 5 refs., 1 fig., 1 tab.

  1. Use of labeled primers for differential display

    SciTech Connect (OSTI)

    Paunesku, T.; Woloschak, G.E.

    1995-01-01

    Two artifacts introduced in using differential display technology are (1) random priming from dT present from affinity purification of PolyA+ RNA and (2) hybridization of the arbitrary primer to template target sequences on both cDNA strands. We have developed a method eliminating both problems. By separately using 5`-end-labeled (T){sub 12}XY and arbitrary primers to label bands and comparing two differential display patterns, we can detect only those products incorporating the (T){sub 12}XY primer on the 3` ends and the arbitrary primer on 5` ends. Those bands that are generated randomly in the PCR are readily detectable and can be ignored.

  2. DOE Challenge Home Label Methodology | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Label Methodology DOE Challenge Home Label Methodology A document of the U.S. Department of Energy's Zero Energy Ready Home (formerly Challenge Home) program. ch_label_methodology_1012.pdf (222.71 KB) More Documents & Publications DOE Zero Energy Ready Home Partner Resources Indoor airPLUS Construction Specifications Indoor airPLUS Construction Specifications Version 1 (Rev. 02)

  3. Colloid labelled with radionuclide and method

    DOE Patents [OSTI]

    Atcher, R.W.; Hines, J.J.

    1990-11-13

    A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints. No Drawings

  4. Colloid labelled with radionuclide and method

    DOE Patents [OSTI]

    Atcher, Robert W.; Hines, John J.

    1990-01-01

    A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.

  5. Method of making colloid labeled with radionuclide

    DOE Patents [OSTI]

    Atcher, Robert W.; Hines, John J.

    1991-01-01

    A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.

  6. North America Energy Efficiency Standards and Labeling

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    North American Energy Efficiency Standards and Labeling North American Energy Working Group NORTH AMERICAN ENERGY WORKING GROUP The North American Energy Working Group (NAEWG) was established in spring of 2001 by the Canadian Minister of Natural Resources, the Mexican Secretary of Energy and the U.S. Secretary of Energy, to enhance North American energy cooperation. The Group is led by officials from Natural Resources Canada, the Mexican Secretariat of Energy, and the U.S. Department of Energy.

  7. PVMRW2013 Wed., Feb. 27, 10:00 Discussion notes: | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    0:00 Discussion notes: PVMRW2013 Wed., Feb. 27, 10:00 Discussion notes: We hear that the ... PVMRW2013 Discussion notes: Tues. Feb. 26: 10:45 PVMRW2013 Wed., Feb. 27, 1:45 Discussion ...

  8. PVMRW2013 Wed., Feb. 27, 1:45 Discussion notes | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    1:45 Discussion notes PVMRW2013 Wed., Feb. 27, 1:45 Discussion notes It could be useful to ... More Documents & Publications PVMRW2013 Wed., Feb. 27, 10:00 Discussion notes: PVMRW2013 ...

  9. Federal Utility Partnership Working Group Meeting Notes | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Energy Meeting Notes Federal Utility Partnership Working Group Meeting Notes Spring 2013 Meeting Report (510.93 KB) Fall 2012 Meeting Report (606.19 KB) Spring 2012 Meeting Report (307.53 KB) Fall 2011 Meeting Report (242.64 KB) Spring 2011 Meeting Report (192.73 KB) Fall 2010 Meeting Report (142.42 KB) Spring 2009 Meeting Report (137.93 KB) Fall 2008 Meeting Report (230.19 KB) Fall 2007 Meeting Report (215.46 KB) Spring 2007 Meeting Report (91.39 KB) Fall 2006 Meeting Report (125.64 KB)

  10. Energy-efficient appliance labeling in China: Lessons for successful labeling programs in varied markets

    SciTech Connect (OSTI)

    Lin, Jiang; Townend, Jeanne; Fridley, David; McNeil, Gary; Silva, Tony; Clark, Robin

    2002-08-20

    Appliance ownership and production has increased dramatically in China in the past two decades. From extremely low levels in 1980, China's appliance industry has become one of the largest in the world, with sales topping U.S. $14.4 billion in 2000. In 1981, less than 1 percent of urban Chinese households owned a refrigerator; by 1998, that number had increased to over 75 percent. This dramatic increase in sales and ownership leads to an excellent opportunity to impact energy consumption in China by affecting the energy efficiency of appliances being bought and sold. In general, Chinese consumers value energy efficiency and are knowledgeable about the operating costs of major appliances. However, the Chinese marketplace does not provide information that consumers trust about the energy consumption of specific products. Thus, several interdependent organizations have emerged in China to provide information and market supports for energy efficiency. This paper describes the appliance market in China and the evolution of its standards and labeling programs and the agencies that implement them. It discusses the authors' work with these organizations in developing energy efficiency criteria and supporting an energy efficiency endorsement labeling program in China. It describes how the authors have used their experience with ENERGY STAR{reg_sign} and other programs in the U.S. to work with China to develop a successful program specific to Chinese conditions, with a particular emphasis on refrigerators. It then gives the author's market assessment of the Chinese refrigerator market and recommendations for a successful labeling program and transferable lessons for developing energy efficiency labeling programs in varied markets. This paper is based on the authors' market research, their support in setting energy efficiency criteria in China, interviews with Chinese manufacturers, retailers, and sales staff, and the development and implementation of labeling strategies and

  11. Tribal Consultation and Stakeholder Outreach Meeting Notes and Analysis

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Strategy on the Arctic Region (NSAR) - Ten Year Renewable Energy Strategy Tribal Consultation and Stakeholder Outreach Meeting Notes and Analysis Prepared by Denali Daniels and Associates, Inc. Fall 2014 Office of Indian Energy Table o f C ontents Executive S ummary .............................................................................................................................................. 2 --- 6 Background

  12. CD Label and Package Templates | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Publications, Exhibits, & Logos » Templates » CD Label and Package Templates CD Label and Package Templates The Office of Energy Efficiency and Renewable Energy (EERE) has developed templates for CD labels and CD packages. These can be used for all EERE products. Both templates are available as EPS files, which can be downloaded and edited in a graphics package like Adobe Illustrator. You are not required to use these templates for your EERE products. These templates were designed to allow

  13. Lumens and the Lighting Facts Label | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Lumens and the Lighting Facts Label Lumens and the Lighting Facts Label Energy 101 Lumens: The new way to shop for light lighting_sub.jpg When you're shopping for lightbulbs, compare lumens to be sure you're getting the amount of light, or level of brightness, you want. The Lighting Facts Label will help. This new label will make it easy to compare bulb brightness, color, life, and estimated operating cost for the year. Buy Lumens, Not Watts In the past, we bought lightbulbs based on how much

  14. Widget:LabelMandatoryFields | Open Energy Information

    Open Energy Information (Open El) [EERE & EIA]

    Jump to: navigation, search This widget labels any mandatory form fields with a red asterik. Matches on css selectors formtable and mandatoryField. Retrieved from "http:...

  15. Beryllium-7 labeled carbon particles and method of making

    DOE Patents [OSTI]

    Richards, P.; Mausner, L.F.; Prach, T.F.

    1987-11-17

    Beryllium-7 labeled carbon particles made from the proton irradiation of carbon materials, preferably from dry carbon black are disclosed. Such particles are useful as gamma emitting radiotracers.

  16. Beryllium-7 labeled carbon particles and method of making

    DOE Patents [OSTI]

    Richards, P.; Mausner, L.F.; Prach, T.F.

    1985-04-29

    Beryllium-7 labeled carbon particles made from the proton irradiation of carbon materials, preferably from dry carbon black are disclosed. Such particles are useful as gamma emitting radiotracers.

  17. Beryllium-7 labeled carbon particles and method of making

    DOE Patents [OSTI]

    Richards, Powell; Mausner, Leonard F.; Prach, Thomas F.

    1987-01-01

    Beryllium-7 labeled carbon particles made from the proton irradiation of carbon materials, preferably from dry carbon black are disclosed. Such particles are useful as gamma emitting radiotracers.

  18. Efficient and selective isotopic labeling of hemes to facilitate...

    Office of Scientific and Technical Information (OSTI)

    This method achieves, in a single step, efficient expression and incorporation of hemes isotopically labeled in specific atom positions adequate for spectroscopic characterization ...

  19. A New F-18 Labeled PET Agent For Imaging Alzheimer's Plaques

    SciTech Connect (OSTI)

    Kulkarni, Padmakar V.; Hao Guiyang; Arora, Veera; Long, Michael; Slavine, Nikolai; Chiguru, Srinivas; Qu Baoxi; Sun Xiankai; Bennett, Michael; Antich, Peter P.; Bonte, Frederick J.; Vasdev, Neil

    2011-06-01

    Amyloid plaques and neurofibrillary tangles are hallmarks of Alzheimer's disease (AD). Advances in development of imaging agents have focused on targeting amyloid plaques. Notable success has been the development of C-11 labeled PIB (Pittsburgh Compound) and a number of studies have demonstrated the utility of this agent. However, the short half life of C-11 (t1/2: 20 min), is a limitation, thus has prompted the development of F-18 labeled agents. Most of these agents are derivatives of amyloid binding dyes; Congo red and Thioflavin. Some of these agents are in clinical trials with encouraging results. We have been exploring new class of agents based on 8-hydroxy quinoline, a weak metal chelator, targeting elevated levels of metals in plaques. Iodine-123 labeled clioquinol showed affinity for amyloid plaques however, it had limited brain uptake and was not successful in imaging in intact animals and humans. We have been successful in synthesizing F-18 labeled 8-hydroxy quinoline. Small animal PET/CT imaging studies with this agent showed high (7-10% ID/g), rapid brain uptake and fast washout of the agent from normal mice brains and delayed washout from transgenic Alzheimer's mice. These promising results encouraged us in further evaluation of this class of compounds for imaging AD plaques.

  20. LLW Notes, Volume 9, Number 6. October 1994

    SciTech Connect (OSTI)

    1994-10-01

    LLW Notes is distributed to Low-Level Radioactive Waste Forum Participants and other state and compact officials identified by those Participants to receive LLW Notes. The Low-Level Radioactive Waste Forum is an association of state and compact representatives appointed by governors and compact commissions, established to facilitate state and compact commission implementation of the Low- Level Radioactive Waste Policy Act of 1980 and the Low-Level Radioactive Waste Policy Amendments Act of 1985 and to promote the objectives of low-level radioactive waste regional compacts. The Forum provides an opportunity for states and compacts to share information with one another and to exchange views with officials of federal agencies and other interested parties.

  1. Note: Fast neutron efficiency in CR-39 nuclear track detectors

    SciTech Connect (OSTI)

    Cavallaro, S.

    2015-03-15

    CR-39 samples are commonly employed for fast neutron detection in fusion reactors and in inertial confinement fusion experiments. The literature reported efficiencies are strongly depending on experimental conditions and, in some cases, highly dispersed. The present note analyses the dependence of efficiency as a function of various parameters and experimental conditions in both the radiator-assisted and the stand-alone CR-39 configurations. Comparisons of literature experimental data with Monte Carlo calculations and optimized efficiency values are shown and discussed.

  2. Application note : using open source schematic capture tools with Xyce.

    SciTech Connect (OSTI)

    Russo, Thomas V.

    2013-08-01

    The development of the XyceTM Parallel Electronic Simulator has focused entirely on the creation of a fast, scalable simulation tool, and has not included any schematic capture or data visualization tools. This application note will describe how to use the open source schematic capture tool gschem and its associated netlist creation tool gnetlist to create basic circuit designs for Xyce, and how to access advanced features of Xyce that are not directly supported by either gschem or gnetlist.

  3. Labeling of indocyanine green with carrier-free iodine-123

    DOE Patents [OSTI]

    Ansari, Azizullah N.; Lambrecht, Richard M.; Redvanly, Carol S.; Wolf, Alfred P.

    1976-01-01

    The method of labeling indocyanine green (ICG) with carrier-free iodine-123 comprising the steps of condensing xenon-123 on crystals of ICG followed by permitting decay of the .sup.123 Xe a sufficient length of time to produce .sup.123 I-electronically excited ions and atoms which subsequently label ICG.

  4. Tritium labeling of organic compounds deposited on porous structures

    DOE Patents [OSTI]

    Ehrenkaufer, Richard L. E.; Wolf, Alfred P.; Hembree, Wylie C.

    1979-01-01

    An improved process for labeling organic compounds with tritium is carried out by depositing the selected compound on the extensive surface of a porous structure such as a membrane filter and exposing the membrane containing the compound to tritium gas activated by the microwave discharge technique. The labeled compound is then recovered from the porous structure.

  5. Holographic Labeling And Reading Machine For Authentication And Security Appications

    DOE Patents [OSTI]

    Weber, David C.; Trolinger, James D.

    1999-07-06

    A holographic security label and automated reading machine for marking and subsequently authenticating any object such as an identification badge, a pass, a ticket, a manufactured part, or a package is described. The security label is extremely difficult to copy or even to read by unauthorized persons. The system comprises a holographic security label that has been created with a coded reference wave, whose specification can be kept secret. The label contains information that can be extracted only with the coded reference wave, which is derived from a holographic key, which restricts access of the information to only the possessor of the key. A reading machine accesses the information contained in the label and compares it with data stored in the machine through the application of a joint transform correlator, which is also equipped with a reference hologram that adds additional security to the procedure.

  6. Synthesis of labeled oxalic acid derivatives

    DOE Patents [OSTI]

    Martinez, Rodolfo A.; Unkefer, Clifford J.; Alvarez, Marc A.

    2004-06-22

    The present invention is directed to labeled compounds, specifically ##STR1## where each C* is selected from the group consisting of a carbon-12, i.e., .sup.12 C, or a carbon-13, i.e., .sup.13 C and at least one C* is .sup.13 C, R.sup.1 is selected from the group of C.sub.1 -C.sub.4 lower alkyl and aryl, and X is selected from the group of --NR.sup.2 R.sup.3 where R.sup.2 and R.sup.3 are each independently selected from the group of C.sub.1 -C.sub.4 lower alkyl, alkoxy and aryl, --SR.sup.4 where R.sup.4 is selected from the group of C.sub.1 -C.sub.4 lower alkyl, alkoxy and aryl, and --OR.sup.5 where R.sup.5 is selected from the group of C.sub.1 -C.sub.4 lower alkyl, alkoxy and aryl with the proviso that when R.sup.1 is methyl then R.sup.5 is other than methyl, when R.sup.1 is ethyl then R.sup.5 is other than ethyl, and when R.sup.1 is benzyl then R.sup.5 is other than benzyl.

  7. MICROBOONE-NOTE-1008-PUB Michel Electron Reconstruction Using

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    8-PUB Michel Electron Reconstruction Using the MicroBooNE LArTPC Cosmic Data The MicroBooNE Collaboration August 25, 2016 Abstract MicroBooNE is a Liquid Argon Time Projection Chamber (LArTPC) neutrino detector located in the Booster Neutrino Beamline at Fermilab which began collecting neutrino data in October 2015. MicroBooNE aims to explore the low-energy excess in the ν e spectrum reported by MiniBooNE as well as perform ν-Ar cross-section measurements. In this note, we present the current

  8. COLLOQUIUM: NOTE SPECIAL DATE - THURSDAY: Unique Vulnerability of the New

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    York/New Jersey Metro Region to Hurricane Destruction - A New Perspective Based on Recent Research on Irene 2011 and Sandy 2012 | Princeton Plasma Physics Lab February 28, 2013, 4:15pm to 5:30pm Colloquia MBG Auditorium COLLOQUIUM: NOTE SPECIAL DATE - THURSDAY: Unique Vulnerability of the New York/New Jersey Metro Region to Hurricane Destruction - A New Perspective Based on Recent Research on Irene 2011 and Sandy 2012 Professor Nicholas K. Coch Queens College CUNY In the last two years. the

  9. V-147: IBM Lotus Notes Mail Client Lets Remote Users Execute...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    7: IBM Lotus Notes Mail Client Lets Remote Users Execute Java Applets V-147: IBM Lotus Notes Mail Client Lets Remote Users Execute Java Applets May 2, 2013 - 6:00am Addthis...

  10. U.S. Department of Energy Onboard Storage Tank Workshop Notes | Department

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    of Energy Onboard Storage Tank Workshop Notes U.S. Department of Energy Onboard Storage Tank Workshop Notes These notes and action items were derived from the Onboard Storage Tank Workshop on April 29, 2010. workshop_notes_ostw.pdf (108.08 KB) More Documents & Publications DOE Vehicular Tank Workshop Agenda Hydrogen Tank Testing R&D Developing SAE Safety Standards for Hydrogen and Fuel Cell Vehicles (FCVs)

  11. Optimization of preparation of Rh-105 labeled (B72.3) MOAB using an amine oxime ligand and comparison of its biodistribution with I-131 labeled B72.3 MOAB

    SciTech Connect (OSTI)

    Venkatesh, M.; Kilcoin, T.T.; Schlemper, E.O.

    1994-05-01

    Propyleneamineoxime ligands with the four N donor atoms form stable complexes with Rh(III). The p-aminobenzylpropyleneamineoxime ligand (L) was made to act as a bifunctional chelating agent to label proteins with Rh-105. This study encompasses the optimization of formation of the Rh-105 complex of L, its purification, activation with thiophosgene, conjugation the B72.3 MOAB, purification by gel filtration, determination of its stability in physiological buffers and in human serum and comparison of the biodistribution Rh-105 labeled antibody with I-131 labeled antibody in normal healthy mice. Rh-105 was complexed with the ligand L by refluxing at pH 5-6 for 45 min. CuCl, was added to form a charged complex and the neutral activated Rh-105 complex extracted into chloroform. Following evaporation of CHC1{sub 3}, the complex was dissolved in 20 {mu}1 of DMF and reconstituted with 0.5 ml of saline. This was then reacted with the B72.3 MOAB in 0.05 M bicarbonate buffer at pH 9 and incubated for 3 h at 37{degrees}C. The complexation yields were generally 95% and the conjugation yields {approximately}60%. The Rh-105 conjugate was stable at room temperature in phosphate buffer saline (pH 7.4), bicarbonate buffer saline (pH 8.5) and human serum at 37{degrees}C for 4 days. >95% of the conjugate remained immunoreactive using mucin-bound to sepharose as the antigen. I-131 labeled antibody was prepared by using iodogen as the oxidizing agent. The two labeled antibodies were co-injected into healthy mice and the biodistribution studied at different time intervals. The biodistribution studies show good correlation between I-131 and Rh-105 labeled B72.3 MOAB preparations over 20 h demonstrating good in vivo stability. This ligand may be useful as a bifunctional chelating agent for Rh-105 labeled antibody.

  12. 99M-Technetium labeled tin colloid radiopharmaceuticals

    DOE Patents [OSTI]

    Winchell, Harry S.; Barak, Morton; Van Fleet, III, Parmer

    1976-07-06

    An improved 99m-technetium labeled tin(II) colloid, size-stabilized for reticuloendothelial organ imaging without the use of macromolecular stabilizers and a packaged tin base reagent and an improved method for making it are disclosed.

  13. Template:LabelValuePair | Open Energy Information

    Open Energy Information (Open El) [EERE & EIA]

    is typically used to display the results of an ask or sparql query in a simple label: value format. It is used by many pages, including the sub pages for country profiles, and is...

  14. Self-assessed performance improves statistical fusion of image labels

    SciTech Connect (OSTI)

    Bryan, Frederick W. Xu, Zhoubing; Asman, Andrew J.; Allen, Wade M.; Reich, Daniel S.; Landman, Bennett A.

    2014-03-15

    Purpose: Expert manual labeling is the gold standard for image segmentation, but this process is difficult, time-consuming, and prone to inter-individual differences. While fully automated methods have successfully targeted many anatomies, automated methods have not yet been developed for numerous essential structures (e.g., the internal structure of the spinal cord as seen on magnetic resonance imaging). Collaborative labeling is a new paradigm that offers a robust alternative that may realize both the throughput of automation and the guidance of experts. Yet, distributing manual labeling expertise across individuals and sites introduces potential human factors concerns (e.g., training, software usability) and statistical considerations (e.g., fusion of information, assessment of confidence, bias) that must be further explored. During the labeling process, it is simple to ask raters to self-assess the confidence of their labels, but this is rarely done and has not been previously quantitatively studied. Herein, the authors explore the utility of self-assessment in relation to automated assessment of rater performance in the context of statistical fusion. Methods: The authors conducted a study of 66 volumes manually labeled by 75 minimally trained human raters recruited from the university undergraduate population. Raters were given 15 min of training during which they were shown examples of correct segmentation, and the online segmentation tool was demonstrated. The volumes were labeled 2D slice-wise, and the slices were unordered. A self-assessed quality metric was produced by raters for each slice by marking a confidence bar superimposed on the slice. Volumes produced by both voting and statistical fusion algorithms were compared against a set of expert segmentations of the same volumes. Results: Labels for 8825 distinct slices were obtained. Simple majority voting resulted in statistically poorer performance than voting weighted by self-assessed performance

  15. Hanford Site Beryllium Posting and Labeling Requirements Procedure

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    -003 Revision 1 Hanford Site Beryllium Posting and Labeling Requirements Procedure Prepared for the U.S. Department of Energy Assistant Secretary for Environmental Management Approved for Public Release; Further Dissemination Unlimited DOE-0342-003, Rev. 1 Hanford Site Beryllium Posting and Labeling Requirements Procedure Published Date: 09-19-2013 Effective Date: 05-14-2014 Change Summary Page 1 of 1 Change Summary Revision # Date/Section Changed Change Details 1 3/19/13, Misc. changes as

  16. Calendar Year 2007 Program Benefits for ENERGY STAR Labeled Products

    SciTech Connect (OSTI)

    Sanchez, Marla Christine; Homan, Gregory; Brown, Richard

    2008-10-31

    ENERGY STAR is a voluntary energy efficiency-labeling program operated jointly by the United States Department of Energy and the United States Environmental Protection Agency (US EPA). Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products. ENERGY STAR's central role in the development of regional, national, and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with committed stakeholders. Through 2007, the program saved 7.1 Quads of primary energy and avoided 128 MtC equivalent. The forecast shows that the program is expected to save 21.2 Quads of primary energy and avoid 375 MtC equivalent over the period 2008-2015. The sensitivity analysis bounds the best estimate of carbon avoided between 84 MtC and 172 MtC (1993 to 2007) and between 243 MtC and 519 MtC (2008 to 2015).

  17. Calendar Year 2007 Program Benefits for U.S. EPA Energy Star Labeled Products: Expanded Methodology

    SciTech Connect (OSTI)

    Sanchez, Marla; Homan, Gregory; Lai, Judy; Brown, Richard

    2009-09-24

    This report provides a top-level summary of national savings achieved by the Energy Star voluntary product labeling program. To best quantify and analyze savings for all products, we developed a bottom-up product-based model. Each Energy Star product type is characterized by product-specific inputs that result in a product savings estimate. Our results show that through 2007, U.S. EPA Energy Star labeled products saved 5.5 Quads of primary energy and avoided 100 MtC of emissions. Although Energy Star-labeled products encompass over forty product types, only five of those product types accounted for 65percent of all Energy Star carbon reductions achieved to date, including (listed in order of savings magnitude)monitors, printers, residential light fixtures, televisions, and furnaces. The forecast shows that U.S. EPA?s program is expected to save 12.2 Quads of primary energy and avoid 215 MtC of emissions over the period of 2008?2015.

  18. V-229: IBM Lotus iNotes Input Validation Flaws Permit Cross-Site Scripting

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Attacks | Department of Energy 9: IBM Lotus iNotes Input Validation Flaws Permit Cross-Site Scripting Attacks V-229: IBM Lotus iNotes Input Validation Flaws Permit Cross-Site Scripting Attacks August 28, 2013 - 6:00am Addthis PROBLEM: Several vulnerabilities were reported in IBM Lotus iNotes PLATFORM: IBM Lotus iNotes 8.5.x ABSTRACT: IBM Lotus iNotes 8.5.x contains four cross-site scripting vulnerabilities REFERENCE LINKS: Security Tracker Alert ID 1028954 IBM Security Bulletin 1647740

  19. V-211: IBM iNotes Multiple Vulnerabilities | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    1: IBM iNotes Multiple Vulnerabilities V-211: IBM iNotes Multiple Vulnerabilities August 5, 2013 - 6:00am Addthis PROBLEM: Multiple vulnerabilities have been reported in IBM Lotus iNotes PLATFORM: IBM iNotes 9.x ABSTRACT: IBM iNotes has two cross-site scripting vulnerabilities and an ActiveX Integer overflow vulnerability REFERENCE LINKS: Secunia Advisory SA54436 IBM Security Bulletin 1645503 CVE-2013-3027 CVE-2013-3032 CVE-2013-3990 IMPACT ASSESSMENT: High DISCUSSION: 1) Certain input related

  20. NREL: Wind Research - Wind Career Map Shows Wind Industry Career...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Wind Career Map Shows Wind Industry Career Opportunities, Paths A screenshot of the wind career map showing the various points on a chart that show different careers in the wind...

  1. Statistics Show Bearing Problems Cause the Majority of Wind Turbine...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Statistics Show Bearing Problems Cause the Majority of Wind Turbine Gearbox Failures Statistics Show Bearing Problems Cause the Majority of Wind Turbine Gearbox Failures September ...

  2. Water telescope's first sky map shows flickering black holes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Water telescope's first sky map shows flickering black holes Water telescope's first sky map shows flickering black holes The High Altitude Water Cherenkov observatory has released ...

  3. Federal Energy Management Trade Show | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Federal Energy Management Trade Show Federal Energy Management Trade Show Addthis 1 of 4 Timothy Unruh, Program Manager for the Office of Energy Efficiency and Renewable Energy...

  4. Plasma research shows promise for future compact accelerators

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Plasma research shows promise for future compact accelerators Plasma research shows promise for future compact accelerators A transformative breakthrough in controlling ion beams ...

  5. Pumped-Storage Hydropower Shows Promise for Boosting Energy Storage...

    Energy Savers

    Pumped-Storage Hydropower Shows Promise for Boosting Energy Storage Pumped-Storage Hydropower Shows Promise for Boosting Energy Storage August 23, 2016 - 10:45am Addthis ...

  6. DOE Releases New Analysis Showing Significant Advances in Electric...

    Office of Environmental Management (EM)

    Analysis Showing Significant Advances in Electric Vehicle Deployment DOE Releases New Analysis Showing Significant Advances in Electric Vehicle Deployment February 8, 2011 - ...

  7. Shanghai Hi Show Photovoltaic Science Technology Co Ltd | Open...

    Open Energy Information (Open El) [EERE & EIA]

    Hi Show Photovoltaic Science Technology Co Ltd Jump to: navigation, search Name: Shanghai Hi-Show Photovoltaic Science & Technology Co., Ltd Place: Shanghai Municipality, China...

  8. NREL Refinery Process Shows Increased Effectiveness of Producing...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Refinery Process Shows Increased Effectiveness of Producing Ethanol from Algae NREL Refinery Process Shows Increased Effectiveness of Producing Ethanol from Algae February 11, 2016 ...

  9. Simulations Show Swirling Rings, Whirlpool-Like Structure in Subatomic

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    'Soup' Simulations Show Swirling Rings, Whirlpool-Like Structure in Subatomic 'Soup'

  10. Nanoimages show disruption of tubulin polymerization by chlorpyrifos oxon: Implications for neurotoxicity

    SciTech Connect (OSTI)

    Grigoryan, Hasmik; Lockridge, Oksana

    2009-10-15

    Organophosphorus agents cause cognitive deficits and depression in some people. We hypothesize that the mechanism by which organophosphorus agents cause these disorders is by modification of proteins in the brain. One such protein could be tubulin. Tubulin polymerizes to make the microtubules that transport cell components to nerve axons. The goal of the present work was to measure the effect of the organophosphorus agent chlorpyrifos oxon on tubulin polymerization. An additional goal was to identify the amino acids covalently modified by chlorpyrifos oxon in microtubule polymers and to compare them to the amino acids modified in unpolymerized tubulin dimers. Purified bovine tubulin (0.1 mM) was treated with 0.005-0.1 mM chlorpyrifos oxon for 30 min at room temperature and then polymerized by addition of 1 mM GTP to generate microtubules. Microtubules were visualized by atomic force microscopy. Chlorpyrifos oxon-modified residues were identified by tandem ion trap electrospray ionization and matrix-assisted laser desorption/ionization mass spectrometry of tryptic peptides. Nanoimaging showed that low concentrations (0.005 and 0.01 mM) of chlorpyrifos oxon yielded short, thin microtubules. A concentration of 0.025 mM stimulated polymerization, while high concentrations (0.05 and 0.1 mM) caused aggregation. Of the 17 tyrosines covalently modified by chlorpyrifos oxon in unpolymerized tubulin dimers, only 2 tyrosines were labeled in polymerized microtubules. The two labeled tyrosines in polymerized tubulin were Tyr 103 in EDAANNY*R of alpha tubulin, and Tyr 281 in GSQQY*R of beta tubulin. In conclusion, chlorpyrifos oxon binding to tubulin disrupts tubulin polymerization. These results may lead to an understanding of the neurotoxicity of organophosphorus agents.

  11. Note: Inter-satellite laser range-rate measurement by using digital phase locked loop

    SciTech Connect (OSTI)

    Liang, Yu-Rong; Duan, Hui-Zong; Xiao, Xin-Long; Wei, Bing-Bing; Yeh, Hsien-Chi

    2015-01-15

    This note presents an improved high-resolution frequency measurement system dedicated for the inter-satellite range-rate monitoring that could be used in the future’s gravity recovery mission. We set up a simplified common signal test instead of the three frequencies test. The experimental results show that the dominant noises are the sampling time jitter and the thermal drift of electronic components, which can be reduced by using the pilot-tone correction and passive thermal control. The improved noise level is about 10{sup −8} Hz/Hz{sup 1/2}@0.01Hz, limited by the signal-to-noise ratio of the sampling circuit.

  12. Understanding the Environmental Impacts of Electricity: Product Labeling and Certification

    SciTech Connect (OSTI)

    Bird, L.

    2003-01-01

    Electricity consumers are increasingly gaining the ability to choose among power options from either their current electric utilities or from alternative power providers. In order to help consumers make informed decisions about their electricity purchases and to compare alternatives, many states are requiring electricity providers to disclose information regarding the fuel sources used to generate electricity and the associated environmental impacts. Like nutrition labels, environmental disclosure labels present the content or sources of electricity and are typically included with electricity bills and in product offers. These labels allow consumers to compare the environmental impacts of standard and cleaner power options, which are typically available. This paper discusses clean, green power options available to power purchasers and the tools and information that can be used to make more sustainable power purchase decisions.

  13. Data-Parallel Mesh Connected Components Labeling and Analysis

    SciTech Connect (OSTI)

    Harrison, Cyrus; Childs, Hank; Gaither, Kelly

    2011-04-10

    We present a data-parallel algorithm for identifying and labeling the connected sub-meshes within a domain-decomposed 3D mesh. The identification task is challenging in a distributed-memory parallel setting because connectivity is transitive and the cells composing each sub-mesh may span many or all processors. Our algorithm employs a multi-stage application of the Union-find algorithm and a spatial partitioning scheme to efficiently merge information across processors and produce a global labeling of connected sub-meshes. Marking each vertex with its corresponding sub-mesh label allows us to isolate mesh features based on topology, enabling new analysis capabilities. We briefly discuss two specific applications of the algorithm and present results from a weak scaling study. We demonstrate the algorithm at concurrency levels up to 2197 cores and analyze meshes containing up to 68 billion cells.

  14. Simple, rapid method for the preparation of isotopically labeled formaldehyde

    DOE Patents [OSTI]

    Hooker, Jacob Matthew; Schonberger, Matthias; Schieferstein, Hanno; Fowler, Joanna S.

    2011-10-04

    Isotopically labeled formaldehyde (*C.sup..sctn.H.sub.2O) is prepared from labeled methyl iodide (*C.sup..sctn.H.sub.3I) by reaction with an oxygen nucleophile having a pendant leaving group. The mild and efficient reaction conditions result in good yields of *C.sup..sctn.H.sub.2O with little or no *C isotopic dilution. The simple, efficient production of .sup.11CH.sub.2O is described. The use of the .sup.11CH.sub.2O for the formation of positron emission tomography tracer compounds is described. The reaction can be incorporated into automated equipment available to radiochemistry laboratories. The isotopically labeled formaldehyde can be used in a variety of reactions to provide radiotracer compounds for imaging studies as well as for scintillation counting and autoradiography.

  15. Semiconductor Quantum Rods as Single Molecule FluorescentBiological Labels

    SciTech Connect (OSTI)

    Fu, Aihua; Gu, Weiwei; Boussert, Benjamine; Koski, Kristie; Gerion, Daniele; Manna, Liberato; Le Gros, Mark; Larabell, Carolyn; Alivisatos, A. Paul

    2006-05-29

    In recent years, semiconductor quantum dots have beenapplied with great advantage in a wide range of biological imagingapplications. The continuing developments in the synthesis of nanoscalematerials and specifically in the area of colloidal semiconductornanocrystals have created an opportunity to generate a next generation ofbiological labels with complementary or in some cases enhanced propertiescompared to colloidal quantum dots. In this paper, we report thedevelopment of rod shaped semiconductor nanocrystals (quantum rods) asnew fluorescent biological labels. We have engineered biocompatiblequantum rods by surface silanization and have applied them fornon-specific cell tracking as well as specific cellular targeting. Theproperties of quantum rods as demonstrated here are enhanced sensitivityand greater resistance for degradation as compared to quantum dots.Quantum rods have many potential applications as biological labels insituations where their properties offer advantages over quantumdots.

  16. Volume-labeled nanoparticles and methods of preparation

    SciTech Connect (OSTI)

    Wang, Wei; Gu, Baohua; Retterer, Scott T; Doktycz, Mitchel J

    2015-04-21

    Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.

  17. CEM_Metrics_and_Technical_Note_7_14_10.pdf | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    CEM_Metrics_and_Technical_Note_7_14_10.pdf CEM_Metrics_and_Technical_Note_7_14_10.pdf (129.47 KB) More Documents & Publications SEAD-Fact-Sheet.pdf Schematics of a heat pump clothes dryer<br /> Credit: Oak Ridge National Lab Heat Pump Clothes Dryer CEM_Metrics_and_Technical_Note_7_14_10.pdf Wind Vision: A New Era for Wind Power in the United States

  18. A Look Inside the Detroit Auto Show | Department of Energy

    Energy Savers

    the Detroit Auto Show A Look Inside the Detroit Auto Show January 12, 2011 - 1:15pm Addthis Kerry Duggan Kerry Duggan Waking up at 4:30AM is not my idea of fun. But after I ...

  19. Interactive Map Shows Thousands of Sandia Labs Collaborations...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Interactive Map Shows Thousands of Sandia Labs Collaborations Across U.S. Interactive Map Shows Thousands of Sandia Labs Collaborations Across U.S. March 8, 2016 - 2:46pm Addthis ...

  20. New Interactive Map Shows Big Potential for America's Wind Energy...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Interactive Map Shows Big Potential for America's Wind Energy Future New Interactive Map Shows Big Potential for America's Wind Energy Future March 31, 2015 - 11:50am Addthis Wind ...

  1. Show Me the Money!: How to Find Financing, Access Incentives...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Show Me the Money: How to Find Financing, Access Incentives, and Get Projects Done Show Me the Money: How to Find Financing, Access Incentives, and Get Projects Done December 6, ...

  2. New Report Shows Downward Trend in LCOE for Wind | Department...

    Office of Environmental Management (EM)

    New Report Shows Downward Trend in LCOE for Wind New Report Shows Downward Trend in LCOE for Wind May 18, 2015 - 2:48pm Addthis A new report recently published by the U.S. ...

  3. New Geothermal Prospects in the Western United States Show Promise...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Geothermal Prospects in the Western United States Show Promise New Geothermal Prospects in the Western United States Show Promise February 27, 2013 - 2:21pm Addthis New geothermal ...

  4. Dynein Motor Domain Shows Ring-Shaped Motor, Buttress

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Dynein Motor Domain Shows Ring-Shaped Motor, Buttress Dynein Motor Domain Shows Ring-Shaped Motor, Buttress Print Monday, 28 November 2011 14:52 Movement is fundamental to life. It...

  5. Native American Heritage Month (NAHM) - Cultural Film Showing |

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Department of Energy Native American Heritage Month (NAHM) - Cultural Film Showing Native American Heritage Month (NAHM) - Cultural Film Showing November 14, 2016 10:00AM to 11:00AM EST Native American Heritage Month (NAHM) - Cultural Film Showing

  6. Getting the Most Out of a Show | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Publications, Exhibits, & Logos » Getting the Most Out of a Show Getting the Most Out of a Show These guidelines are designed to assist you during the event, in order to get the most out of the showing of your exhibit. Look the Part Create a good impression for EERE by looking polished and professional. Wear business-like, comfortable attire. Don't forget your nametag! Get plenty of rest before the show, and pace yourself during the show (you will need breaks, so schedule them). Staffing

  7. Label-free three-dimensional imaging of cell nucleus using third-harmonic generation microscopy

    SciTech Connect (OSTI)

    Lin, Jian; Zheng, Wei; Wang, Zi; Huang, Zhiwei

    2014-09-08

    We report the implementation of the combined third-harmonic generation (THG) and two-photon excited fluorescence (TPEF) microscopy for label-free three-dimensional (3-D) imaging of cell nucleus morphological changes in liver tissue. THG imaging shows regular spherical shapes of normal hepatocytes nuclei with inner chromatin structures while revealing the condensation of chromatins and nuclear fragmentations in hepatocytes of diseased liver tissue. Colocalized THG and TPEF imaging provides complementary information of cell nuclei and cytoplasm in tissue. This work suggests that 3-D THG microscopy has the potential for quantitative analysis of nuclear morphology in cells at a submicron-resolution without the need for DNA staining.

  8. Isonitrile radionuclide complexes for labelling and imaging agents

    DOE Patents [OSTI]

    Jones, Alun G.; Davison, Alan; Abrams, Michael J.

    1984-06-04

    A coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta, is useful as a diagnostic agent for labelling liposomes or vesicles, and selected living cells containing lipid membranes, such as blood clots, myocardial tissue, gall bladder tissue, etc.

  9. Palladium-109 labeled anti-melanoma monoclonal antibodies

    DOE Patents [OSTI]

    Srivastava, S.C.; Fawwaz, R.A.; Ferrone, S.

    1984-04-30

    The invention consists of new monoclonal antibodies labelled with Palladium 109, a beta-emitting radionuclide, the method of preparing this material, and its use in the radiotherapy of melanoma. The antibodies are chelate-conjugated and demonstrate a high uptake in melanomas. (ACR)

  10. EIA-906 & EIA-920, and EIA-923 Database Notes

    U.S. Energy Information Administration (EIA) (indexed site)

    for each plant (e.g., NERC region and census region); adding the operator name and EIA operator ID number; showing nuclear data by unit; adding columns that show consumption ...

  11. Los Alamos disease-fighting technology showing promise

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    disease-fighting technology showing promise Los Alamos disease-fighting technology showing promise A pathogen-carrying pest known as the glassy-winged sharpshooter has plagued grape vines in California for more than century, but a new technology from Los Alamos National Laboratory could change that. November 4, 2016 Los Alamos disease-fighting technology showing promise Citrus plants treated with immunity technology, left, and untreated plants. Innate Immunity LLC is developing genetically

  12. 3D Printed Car at the International Manufacturing Technology Show |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy 3D Printed Car at the International Manufacturing Technology Show 3D Printed Car at the International Manufacturing Technology Show Addthis WORLD&#039;S FIRST 1 of 6 WORLD'S FIRST The world's first 3D-printed car on display at the International Manufacturing Technology Show in Chicago last week. Arizona-based Local Motors, and Cincinnati Incorporated teamed with Oak Ridge National Laboratory's Manufacturing Demonstration Facility-with funding support from the Energy

  13. Water telescope's first sky map shows flickering black holes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Water telescope's first sky map shows flickering black holes Water telescope's first sky map shows flickering black holes The High Altitude Water Cherenkov observatory has released its first map of the sky, including the first measurements of how often black holes flicker on and off. It has also caught pulsars, supernova remnants, and other bizarre cosmic beasts. April 24, 2016 Water telescope's first sky map shows flickering black holes Three new sources of gamma rays spotted by HAWC. Credit:

  14. New Geothermal Prospects in the Western United States Show Promise |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Geothermal Prospects in the Western United States Show Promise New Geothermal Prospects in the Western United States Show Promise February 27, 2013 - 2:21pm Addthis New geothermal prospects in the western United States show promise, according to the new 2013 Annual U.S. Geothermal Power Production and Development Report, published by the Geothermal Energy Association this week. With an estimate of more than 500 Megawatts of new potential in Oregon alone, industry leader

  15. CHICAGO HOUSE PARTIES SHOW WAYS TO UPGRADE | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    CHICAGO HOUSE PARTIES SHOW WAYS TO UPGRADE CHICAGO HOUSE PARTIES SHOW WAYS TO UPGRADE CHICAGO HOUSE PARTIES SHOW WAYS TO UPGRADE The Chicago Metropolitan Agency for Planning (CMAP) and its partners created Energy Impact Illinois (EI2) to promote home energy upgrades in single-family homes, multifamily housing units, and commercial buildings to help the region meet its 2008 Chicago Climate Action Plan and longer term GO TO 2040 Strategic Plan. EI2 enlisted the help of the Elevate Energy, a

  16. Secretary Moniz Releases Report Showing the Cost Reductions and Rapid

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Deployment of Clean Energy Technologies | Department of Energy Secretary Moniz Releases Report Showing the Cost Reductions and Rapid Deployment of Clean Energy Technologies Secretary Moniz Releases Report Showing the Cost Reductions and Rapid Deployment of Clean Energy Technologies September 28, 2016 - 11:33am Addthis Secretary Moniz Releases Report Showing the Cost Reductions and Rapid Deployment of Clean Energy Technologies NEWS MEDIA CONTACT (202) 586-4940 DOENews@hq.doe.gov During Obama

  17. NREL: Wind Research - New Video Shows How NREL Is Redefining...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    New Video Shows How NREL Is Redefining What's Possible for Renewable Energy Through Grid Integration January 23, 2015 NREL is spearheading engineering innovations that will help...

  18. The Majorana Demonstrator: Progress towards showing the feasibility...

    Office of Scientific and Technical Information (OSTI)

    Authors: Finnerty, P. 1 ; Elliott, Steven R. 2 ; Boswell, Melissa 2 ; Kidd, Mary 2 ; Rielage, Keith R. 2 ; Ronquest, Michael 2 ; Steele, Steven 2 + Show Author ...

  19. NREL: Technology Transfer - New Video Shows How NREL Is Redefining...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    New Video Shows How NREL Is Redefining What's Possible for Renewable Energy Through Grid Integration January 23, 2015 NREL is spearheading engineering innovations that will help...

  20. Analysis shows greenhouse gas emissions similar for shale, crude...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Michael Wang, Argonne senior scientist and lead on the GREET model Analysis shows greenhouse gas emissions similar for shale, crude oil By Tona Kunz * October 15, 2015 Tweet ...

  1. ANL Study Shows Wind Power Decreases Power Sector Emissions ...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    increases, pollutant emissions decrease overall due to the replacement of fossil fuels. "Our study clearly shows that using wind to generate electricity has a discernible ...

  2. SLIDESHOW: Secretary Moniz Tours 2014 Washington Auto Show

    Energy.gov [DOE]

    A slideshow featuring highlights from Secretary Moniz's tour of the 2014 Washington Auto Show is currently posted on the Energy Department's blog.

  3. Sandia Energy - Biofuels Blend Right In: Researchers Show Ionic...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Biofuels Blend Right In: Researchers Show Ionic Liquids Effective for Pretreating Mixed Blends of Biofuel Feedstocks Home Renewable Energy Energy Transportation Energy Biofuels...

  4. Latest Report Shows Cost of Going Solar has Dropped Significantly...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    The report shows that the installed price of distributed solar photovoltaic (PV) power systems in the United States continues to fall precipitously, especially in the last 5 years. ...

  5. ORISE: Report shows nuclear engineering graduation rates on the...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    ORISE report shows nuclear engineering graduation rates on the rise in 2013 Number of ... OAK RIDGE, Tenn.-The number of college students graduating with majors in nuclear ...

  6. ORISE: Report shows nuclear engineering graduation rates rebounding...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    report shows nuclear engineering graduation rates rebounding in 2015 after brief decline ... number of college students graduating with majors in nuclear engineering has rebounded. ...

  7. ORISE: Report shows nuclear engineering graduation rates leveling...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    ORISE report shows nuclear engineering graduation rates leveling off in 2014 after five ... OAK RIDGE, Tenn.-The number of college students graduating with majors in nuclear ...

  8. Widget:ShowRefFieldsButton | Open Energy Information

    Open Energy Information (Open El) [EERE & EIA]

    widget provides supporting functionality to forms that want to capture references for specific values. Specifically, this widget creates the Show Reference Fields button, which...

  9. NREL: Hydrogen and Fuel Cells Research - Evaluation Results Show...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Evaluation Results Show Continued Improvements in Fuel Cell Electric Vehicle Durability, Fuel Economy, Driving Range Project Technology Validation: Fuel Cell Electric Vehicle ...

  10. Argonne Site Map Showing CNM Location | Argonne National Laboratory

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Argonne Site Map Showing CNM Location Find your way to the Center for Nanoscale Materials on the Argonne National Laboratory campus. PDF icon CNM-Argonne_map

  11. User:Nlangle/show map test | Open Energy Information

    Open Energy Information (Open El) [EERE & EIA]

    show map test < User:Nlangle Jump to: navigation, search Loading map... "minzoom":false,"mappingservice":"googlemaps3","type":"ROADMAP","zoom":14,"types":"ROADMAP","SATELLITE","H...

  12. Calendar Year 2008 Program Benefits for ENERGY STAR Labeled Products

    SciTech Connect (OSTI)

    Homan, GregoryK; Sanchez, Marla; Brown, RichardE; Lai, Judy

    2010-08-24

    This paper presents current and projected savings for ENERGY STAR labeled products, and details the status of the model as implemented in the September 2009 spreadsheets. ENERGY STAR is a voluntary energy efficiency labeling program operated jointly by the Environmental Protection Agency (US EPA) and the U.S. Department of Energy (US DOE), designed to identify and promote energy-efficient products, buildings and practices. Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products, and currently labels more than thirty products, spanning office equipment, heating, cooling and ventilation equipment, commercial and residential lighting, home electronics, and major appliances. ENERGY STAR's central role in the development of regional, national and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with stakeholders. This report presents savings estimates for ENERGY STAR labeled products. We present estimates of energy, dollar, and carbon savings achieved by the program in the year 2008, annual forecasts for 2009 and 2010, and cumulative savings estimates for the period 1993 through 2008 and cumulative forecasts for the period 2009 through 2015. Through 2008 the program saved 8.8 Quads of primary energy and avoided the equivalent of 158 metric tones carbon (MtC). The forecast for the period 2009-2015 is 18.1 Quads or primary energy saved and 316 MtC emissions avoided. The sensitivity analysis bounds the best estimate of carbon avoided between 104 MtC and 213 MtC (1993 to 2008) and between 206 MtC and 444 MtC (2009 to 2015). In this report we address the following questions for ENERGY STAR labeled products: (1) How are ENERGY STAR impacts quantified; (2) What are the ENERGY STAR achievements; and (3) What are the limitations to our method?

  13. DOE Booth Presentations From Grainger Show 2015 Downloads

    Energy.gov [DOE]

    DOE hosted its solid-state lighting informational booth February 16–18 at the annual Grainger Show in Orlando, FL. With over 17,000 attendees and over 750 exhibitors, the show gathered a wide range of Grainger customers—from universities to large hotel chains as well as Grainger team members to learn the latest about LED lighting.

  14. EnPI V4.0 Release Notes and Known Issues | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    notes and known issues for the Energy Performance Indicator (EnPI) Tool v4.0. EnPI Release Notes and Known Issues (101.66 KB) More Documents & Publications EnPI V4.0 User Manual

  15. International Review of the Development and Implementation of Energy Efficiency Standards and Labeling Programs

    SciTech Connect (OSTI)

    Zhou, Nan; Zheng, Nina; Fridley, David

    2012-02-28

    . Fourth, sufficient program resources for program implementation and evaluation are critical to the effectiveness of standards and labeling programs and cost-sharing between national and local governments can help ensure adequate resources and uniform implementation. Lastly, check-testing and punitive measures are important forms of enforcement while the cancellation of registration or product sales-based fines have also proven effective in reducing non-compliance. The international comparative analysis also revealed the differing degree to which the level of government decentralization has influenced S&L programs and while no single country has best practices in all elements of standards and labeling development and implementation, national examples of best practices for specific elements do exist. For example, the U.S. has exemplified the use of rigorous analyses for standard-setting and robust data source with the RECS database while Japan's Top Runner standard-setting principle has motivated manufacturers to exceed targets. In terms of standards implementation and enforcement, Australia has demonstrated success with enforcement given its long history of check-testing and enforcement initiatives while mandatory information-sharing between EU jurisdictions on compliance results is another important enforcement mechanism. These examples show that it is important to evaluate not only the drivers of different paths of standards and labeling development, but also the country-specific context for best practice examples in order to understand how and why certain elements of specific S&L programs have been effective.

  16. Annual report shows potential INL radiation dose well below safe...

    Energy.gov (indexed) [DOE]

    The U.S. Department of Energy's Idaho Operations Office reported this month that radiation ... Data shows that the INL site potential radiation dose is less than 1% of the limit of 10 ...

  17. Study Shows Significant Economic Impact from Recovery Act

    Energy.gov [DOE]

    A study recently released shows the $1.6 billion the Savannah River Site (SRS) received from the American Recovery and Reinvestment Act has had a positive economic impact on the adjacent five...

  18. The #LabsRoadShow: National Lab Contributions

    Energy.gov [DOE]

    Join us for Stop Two of the Labs Road Show. All week we'll be highlighting the most notable contributions National Labs have made to science, energy and national security.

  19. New Report Shows Trend Toward Larger Offshore Wind Systems

    Energy.gov [DOE]

    The Energy Department released a new report showing progress for the U.S. offshore wind energy market in 2012, including 11 commercial-scale U.S. projects reaching an advanced stage of development.

  20. NREL Survey Shows Dramatic Improvement in B100 Biodiesel Quality...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Survey Shows Dramatic Improvement in B100 Biodiesel Quality April 15, 2013 The latest national survey of 100% biodiesel (B100) "blend stock" samples by the U.S. Department of ...

  1. Global Climate Change Assessment Report Shows Nations Not Doing...

    Open Energy Information (Open El) [EERE & EIA]

    Global Climate Change Assessment Report Shows Nations Not Doing Enough Home > Blogs > Dc's blog Dc's picture Submitted by Dc(266) Contributor 5 November, 2014 - 14:49 The latest...

  2. Considering removing "Show Preview" button on utility rate form...

    Open Energy Information (Open El) [EERE & EIA]

    Rates I'm considering removing the "Show Preview" button, since it does not work (javascript validation issue that could be fixed), and it doesn't make sense. The reason to...

  3. The Chemistry Magic Show Captivates Kids | GE Global Research

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Chemistry Magic Show Captivates Kids Click to email this to a friend (Opens in new window) Share on Facebook (Opens in new window) Click to share (Opens in new window) Click to ...

  4. 2014 Data Book Shows Increased Use of Renewable Electricity ...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Book shows that U.S. renewable electricity grew to 15.5 percent of total installed capacity and 13.5 percent of total electricity generation. Published annually by the National...

  5. Study Shows Carbon Emission Reductions from City Energy Actions...

    Office of Environmental Management (EM)

    See Figure 2. Graphic with figure 2 images. The results show regional variation in the ... See Figure 3. Graphic of figure 3 images. Key Considerations from the Study Based on the ...

  6. JSON shows incomplete info | OpenEI Community

    Open Energy Information (Open El) [EERE & EIA]

    found several rates where the JSON file doesn't show all of the information shown in the web interface. This is not an approval issue since I see it on both rates that say "This...

  7. Energy Innovation Hub Report Shows Philadelphia-area Building...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Energy Innovation Hub Report Shows Philadelphia-area Building Retrofits Could Support 23,500 Jobs November 10, 2011 - 10:36am Addthis This is the Greater Philadelphia Innovation ...

  8. Secretary Chu Speaks at the 2010 Washington Auto Show

    Office of Energy Efficiency and Renewable Energy (EERE)

    at the 2010 Washington Auto Show, Secretary Chu lays out a roadmap for how the U.S. can lead the world in making the clean vehicles we need. He also announced that the Department of Energy had...

  9. Dynein Motor Domain Shows Ring-Shaped Motor, Buttress

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Dynein Motor Domain Shows Ring-Shaped Motor, Buttress Print Movement is fundamental to life. It takes place even at the cellular level where cargo is continually being transported...

  10. Photo of the Week: the 2014 Washington Auto Show | Department...

    Energy.gov (indexed) [DOE]

    In this photo, a Boy Scout watches light shine on a solar panel that's powering a hydrogen fuel cell system, showing how photovoltaic panels work and energy systems can be ...

  11. 3 Breakthroughs Show How Bioenergy Innovations are Energizing the Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Landscape | Department of Energy Breakthroughs Show How Bioenergy Innovations are Energizing the Energy Landscape 3 Breakthroughs Show How Bioenergy Innovations are Energizing the Energy Landscape October 5, 2016 - 4:30pm Addthis Innovations are moving the bioenergy industry forward. Photos courtesy of Virgin Atlantic (left), Sapphire Energy, Inc. (center), and DC Water’s Blue Plains Advanced Wastewater Treatment Plant (right). Watch the video <a

  12. Plasma research shows promise for future compact accelerators

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Plasma research shows promise for future compact accelerators Plasma research shows promise for future compact accelerators A transformative breakthrough in controlling ion beams allows small-scale laser-plasma accelerators to deliver unprecedented power densities. December 21, 2015 The team in front of the Trident Target Chamber. Back, from left: Tom Shimada, Sha-Marie Reid, Adam Sefkow, Miguel Santiago, and Chris Hamilton. Front, from left: Russ Mortensen, Chengkun Huang, Sasi Palaniyappan,

  13. SLIDESHOW: Secretary Moniz Tours 2014 Washington Auto Show | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Energy Secretary Moniz Tours 2014 Washington Auto Show SLIDESHOW: Secretary Moniz Tours 2014 Washington Auto Show January 22, 2014 - 6:45pm Addthis Hyundai Fuel Cell 1 of 14 Hyundai Fuel Cell Pictured here is Secretary Moniz looking at the fuel cell and motor used to power Hyundai's Tucson fuel cell vehicle. Fuel cell vehicles use hydrogen to produce electricity, which powers an electric motor to make the vehicle and its accessories work. Image: Sarah Gerrity, Energy Department. Date taken:

  14. DOE Releases New Analysis Showing Significant Advances in Electric Vehicle

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Deployment | Department of Energy Analysis Showing Significant Advances in Electric Vehicle Deployment DOE Releases New Analysis Showing Significant Advances in Electric Vehicle Deployment February 8, 2011 - 12:00am Addthis WASHINGTON - The U.S. Department of Energy today released One Million Electric Vehicles by 2015 (pdf - 220 kb), an analysis of advances in electric vehicle deployment and progress to date in meeting President Obama's goal of putting one million electric vehicles on the

  15. New global HIV vaccine design shows promise in monkeys

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    New global HIV vaccine design shows promise in monkeys New global HIV vaccine design shows promise in monkeys These vaccines are specifically designed to present the most common forms of parts of the virus that can be recognized by the immune system. October 30, 2013 Bette Korber of Los Alamos National Laboratory, who developed a component of a new vaccine against HIV, now being tested in monkeys. Bette Korber of Los Alamos National Laboratory, who developed a component of a new vaccine against

  16. The Majorana Demonstrator: Progress towards showing the feasibility of a

    Office of Scientific and Technical Information (OSTI)

    76Ge neutrinoless double-beta decay experiment (Conference) | SciTech Connect Conference: The Majorana Demonstrator: Progress towards showing the feasibility of a 76Ge neutrinoless double-beta decay experiment Citation Details In-Document Search Title: The Majorana Demonstrator: Progress towards showing the feasibility of a 76Ge neutrinoless double-beta decay experiment Authors: Finnerty, P. [1] ; Elliott, Steven R. [2] ; Boswell, Melissa [2] ; Kidd, Mary [2] ; Rielage, Keith R. [2] ;

  17. Award Fee Determination Shows Performance Improvement in WTP Contractor |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Award Fee Determination Shows Performance Improvement in WTP Contractor Award Fee Determination Shows Performance Improvement in WTP Contractor April 14, 2016 - 1:15pm Addthis RICHLAND, Wash. - EM Office of River Protection (ORP) Waste Treatment and Immobilization Plant (WTP) contractor Bechtel National Inc. improved its performance slightly in calendar year 2015 compared to the last half of 2014, earning 66 percent of its possible award fee, or $8.31 million out of a

  18. New Lighting Facts Label: Takes the Guess Work Out of Shopping...

    Energy Savers

    New Lighting Facts Label: Takes the Guess Work Out of Shopping for Light Bulbs New Lighting Facts Label: Takes the Guess Work Out of Shopping for Light Bulbs January 25, 2012 - ...

  19. Methods to radiolabel natural organic matter by reduction with hydrogen labeled reducing agents

    DOE Patents [OSTI]

    Tinnacher, Ruth M.; Honeyman, Bruce D.

    2011-10-18

    Methods to radiolabel natural organic matter by reduction with a hydrogen labeled reducing agent, and compositions, are provided.

  20. The Practice and Thinking of Building Energy Efficiency Evaluation & Labeling in Shanghai

    Energy.gov [DOE]

    Information about the development of Building Energy Efficiency Evaluation and Labeling in Shanghai with project examples and theory.

  1. Imaging endocarditis with Tc-99m-labeled antibody--an experimental study: concise communication

    SciTech Connect (OSTI)

    Wong, D.W.; Dhawan, V.K.; Tanaka, T.; Mishkin, F.S.; Reese, I.C.; Thadepalli, H.

    1982-03-01

    The sensitivity and specificity of Tc-99m-labeled antibacterial antibody (Tc-99m Ab) for detecting bacterial endocarditis were evaluated in an experimental model. Rabbit-produced antistaphylococcal antibody was extracted using Rivanol and chemically labeled with Tc-99m. This Tc-99m Ab was injected intravenously in New Zealand rabbits 24 hr after producing Staphylococcus aureus endocarditis of the aortic valve. Imaging and tissue analyses were performed on the following day. All 11 animals developed S. aureus aortic-valve vegetations and showed increased uptake of Tc-99m Ab at the aortic valve, 118 times higher than at the uninfected tricuspid valve. Although high hepatic radioactivity and anatomic uncertainties interfered with in vivo delineation of these lesions, images of the excised hearts showed all affected valves. Two rabbits inoculated with Escherichia coli did not develop endocarditis and had little uptake of Tc-99m Ab, while six rabbits with enterococcal endocarditis had no uptake of the Tc-99m Ab in their vegetations. The findings suggest potential value of Tc-99m Ab on the rapid diagnosis of endocarditis.

  2. U.S. gasoline prices show little movement (long version)

    U.S. Energy Information Administration (EIA) (indexed site)

    30, 2014 U.S. gasoline prices show little movement (long version) The U.S. average retail price for regular gasoline showed no movement from last week. The average price remained flat at $3.70 a gallon on Monday, based on the weekly price survey by the U.S. Energy Information Administration. Pump prices were highest in the West Coast states at 4.04 a gallon, up 2 ½ cents from a week ago. Prices were lowest in the Gulf Coast region at 3.48 a gallon, down 1.1 cents. This is Amerine Woodyard, with

  3. Secretary Moniz's Remarks at the Washington Auto Show -- As Delivered |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Washington Auto Show -- As Delivered Secretary Moniz's Remarks at the Washington Auto Show -- As Delivered January 22, 2015 - 1:12pm Addthis Dr. Ernest Moniz Dr. Ernest Moniz Secretary of Energy It's a pleasure to be back again this year, as last year was terrific. And as I'll say later on, last year I saw my very first fuel-cell vehicle here. And, as we'll talk about, it was a pretty big year for progress in the fuel-cell world. I was thinking of my own earliest

  4. Bats Offshore? Energy Department Research Study Shows Where and When |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Bats Offshore? Energy Department Research Study Shows Where and When Bats Offshore? Energy Department Research Study Shows Where and When October 24, 2016 - 4:11pm Addthis Photo of a bat detector machine overlooking the ocean. A long-term acoustic survey of bat activity at remote islands, offshore structures, and coastal sites in the Gulf of Maine, Great Lakes, and mid-Atlantic Coast has helped reveal where and when bats fly offshore. The multiyear study, funded by the

  5. New Report Shows Domestic Offshore Wind Industry Potential, 21 Projects

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Planned in U.S. Waters | Department of Energy Domestic Offshore Wind Industry Potential, 21 Projects Planned in U.S. Waters New Report Shows Domestic Offshore Wind Industry Potential, 21 Projects Planned in U.S. Waters September 29, 2015 - 11:30am Addthis The Energy Department today released a new report showing strong progress for the U.S. offshore wind market-including the start of construction of the nation's first commercial-scale offshore wind farm, one of 21 projects totaling 15,650

  6. NREL 2016 Standard Scenarios Outlook Shows Continued Growth in Renewables

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    and Gas in the U.S. Power Sector - News Releases | NREL 2016 Standard Scenarios Outlook Shows Continued Growth in Renewables and Gas in the U.S. Power Sector Webinar on December 6 November 16, 2016 Graph of Renewable Energy Penetration by NREL. Renewable energy penetration in the U.S. power sector as projected by a subset of the Standard Scenarios, where the dashed line shows historical values. Penetration is defined as the fraction of load met by renewable energy. Source: NREL. The Energy

  7. High Performance House Showcased at Builders Show - News Releases | NREL

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    High Performance House Showcased at Builders Show January 20, 2004 Golden, Colo. - Homebuilders attending the 2004 International Builders' Show in Las Vegas can tour a new kind of home-a highly energy-efficient Zero Energy Home that will produce as much electricity as it uses over the course of a year. The U.S. Department of Energy (DOE) and its National Renewable Energy Laboratory (NREL) partnered with Pardee Homes and energy consultant ConSol to introduce the Zero Energy Home concept with this

  8. Assay for vitamin B12 absorption and method of making labeled vitamin B12

    SciTech Connect (OSTI)

    Anderson, Peter J.; Dueker, Stephen; Miller, Joshua; Green, Ralph; Roth, John; Carkeet, Colleen; Buchholz,; Bruce A.

    2012-06-19

    The invention provides methods for labeling vitamin B12 with .sup.14C, .sup.13C, tritium, and deuterium. When radioisotopes are used, the invention provides for methods of labeling B12 with high specific activity. The invention also provides labeled vitamin B12 compositions made in accordance with the invention.

  9. Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels

    DOE Patents [OSTI]

    Mathies, Richard A.; Singhal, Pankaj; Xie, Jin; Glazer, Alexander N.

    2002-01-01

    This invention relates to a microfabricated capillary electrophoresis chip for detecting multiple redox-active labels simultaneously using a matrix coding scheme and to a method of selectively labeling analytes for simultaneous electrochemical detection of multiple label-analyte conjugates after electrophoretic or chromatographic separation.

  10. Single step signal group-imidazole labeling of organic phosphate groups under aqueous conditions

    DOE Patents [OSTI]

    Giese, R.W.; Wang, P.

    1996-04-30

    Compounds and methods for single step, covalent labeling of the phosphate group of an organic substance under aqueous conditions are described. The labeling compound includes any kind of detectable signal group covalently bound to an imidazole moiety, which can be imidazole or a substituted imidazole. A preferred labeling compound has the formula shown in the accompanying diagram. 4 figs.

  11. Single step signal group-imidazole labeling of organic phosphate groups under aqueous conditions

    DOE Patents [OSTI]

    Giese, Roger W.; Wang, Poguang

    1996-01-01

    Compounds and methods for single step, covalent labeling of the phosphate group of an organic substance under aqueous conditions are described. The labeling compound includes any kind of detectable signal group covalently bound to an imidazole moiety, which can be imidazole or a substituted imidazole. A preferred labeling compound has the formula ##STR1##

  12. Labeled ALPHA4BETA2 ligands and methods therefor

    DOE Patents [OSTI]

    Mukherjee, Jogeshwar; Pichika, Ramaiah; Potkin, Steven; Leslie, Frances; Chattopadhyay, Sankha

    2013-02-19

    Contemplated compositions and methods are employed to bind in vitro and in vivo to an .alpha.4.beta.2 nicotinic acetylcholine receptor in a highly selective manner. Where such compounds are labeled, compositions and methods employing such compounds can be used for PET and SPECT analysis. Alternatively, and/or additionally contemplated compounds can be used as antagonists, partial agonists or agonists in the treatment of diseases or conditions associated with .alpha.4.beta..beta.2 dysfunction.

  13. Global Potential of Energy Efficiency Standards and Labeling Programs

    SciTech Connect (OSTI)

    McNeil, Michael A; McNeil, Michael A.; Letschert, Virginie; de la Rue du Can, Stephane

    2008-06-15

    This report estimates the global potential reductions in greenhouse gas emissions by 2030 for energy efficiency improvements associated with equipment (appliances, lighting, and HVAC) in buildings by means of energy efficiency standards and labels (EES&L). A consensus has emerged among the world's scientists and many corporate and political leaders regarding the need to address the threat of climate change through emissions mitigation and adaptation. A further consensus has emerged that a central component of these strategies must be focused around energy, which is the primary generator of greenhouse gas emissions. Two important questions result from this consensus: 'what kinds of policies encourage the appropriate transformation to energy efficiency' and 'how much impact can these policies have'? This report aims to contribute to the dialogue surrounding these issues by considering the potential impacts of a single policy type, applied on a global scale. The policy addressed in this report is Energy Efficient Standards and Labeling (EES&L) for energy-consuming equipment, which has now been implemented in over 60 countries. Mandatory energy performance standards are important because they contribute positively to a nation's economy and provide relative certainty about the outcome (both timing and magnitudes). Labels also contribute positively to a nation's economy and importantly increase the awareness of the energy-consuming public. Other policies not analyzed here (utility incentives, tax credits) are complimentary to standards and labels and also contribute in significant ways to reducing greenhouse gas emissions. We believe the analysis reported here to be the first systematic attempt to evaluate the potential of savings from EES&L for all countries and for such a large set of products. The goal of the analysis is to provide an assessment that is sufficiently well-quantified and accurate to allow comparison and integration with other strategies under

  14. EM Makes Strong Showing in Federal Food Drive

    Energy.gov [DOE]

    WASHINGTON, D.C. – EM made a strong showing in this year’s Feds Feed Families drive, contributing 46,493 pounds of food across the DOE complex and topping it off by winning top prize in a government-wide chili cook-off held at the Department’s headquarters.

  15. Regional Partnership Documentary Wins "Best of Show" Aurora Award

    Energy.gov [DOE]

    A documentary co-produced by Prairie Public Broadcasting and the Plains CO2 Reduction (PCOR) Partnership with support from the U.S. Department of Energy has received a 2012 Platinum Best of Show Aurora Award—the highest honor awarded—in the nature/environment documentary category.

  16. Calendar Year 2009 Program Benefits for ENERGY STAR Labeled Products

    SciTech Connect (OSTI)

    Homan, Gregory K; Sanchez, Marla C.; Brown, Richard E.

    2010-11-15

    ENERGY STAR is a voluntary energy efficiency labeling program operated jointly by the Environmental Protection Agency (US EPA) and the U.S. Department of Energy (US DOE), designed to identify and promote energy-efficient products, buildings and practices. Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products, and currently labels more than thirty products, spanning office equipment, heating, cooling and ventilation equipment, commercial and residential lighting, home electronics, and major appliances. ENERGY STAR's central role in the development of regional, national and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with stakeholders. This report presents savings estimates from the use ENERGY STAR labeled products. We present estimates of energy, dollar, and carbon savings achieved by the program in the year 2009, annual forecasts for 2010 and 2011, and cumulative savings estimates for the period 1993 through 2009 and cumulative forecasts for the period 2010 through 2015. Through 2009 the program saved 9.5 Quads of primary energy and avoided the equivalent of 170 million metric tons carbon (MMTC). The forecast for the period 2009-2015 is 11.5 Quads or primary energy saved and 202 MMTC emissions avoided. The sensitivity analysis bounds the best estimate of carbon avoided between 110 MMTC and 231 MMTC (1993 to 2009) and between 130 MMTC and 285 MMTC (2010 to 2015).

  17. Conference shows high school girls their scientific future | Argonne

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    National Laboratory J'Tia Taylor (left), a nonproliferation technical specialist in Argonne's Nuclear Engineering Division, speaks with event attendees. Click to enlarge. J'Tia Taylor (left), a nonproliferation technical specialist in Argonne's Nuclear Engineering Division, speaks with event attendees. Click to enlarge. Conference shows high school girls their scientific future By Justin H.S. Breaux * April 7, 2014 Tweet EmailPrint ARGONNE, Ill. - Nearly 400 high school girls from the

  18. Los Alamos plasma research shows promise for future compact accelerators |

    National Nuclear Security Administration (NNSA)

    National Nuclear Security Administration | (NNSA) plasma research shows promise for future compact accelerators Tuesday, January 12, 2016 - 12:00am NNSA Blog The team in front of Los Alamos' Trident Laser Target Chamber. Back, from left: Tom Shimada, Sha-Marie Reid, Adam Sefkow, Miguel Santiago, and Chris Hamilton. Front, from left: Russ Mortensen, Chengkun Huang, Sasi Palaniyappan, Juan Fernandez, Cort Gautier and Randy Johnson. A transformative breakthrough in controlling ion beams allows

  19. Research Shows Ventilated Auto Seats Improve Fuel Economy, Comfort - News

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Releases | NREL Research Shows Ventilated Auto Seats Improve Fuel Economy, Comfort March 2, 2006 Golden, Colo. - The U.S. Department of Energy's National Renewable Energy Laboratory (NREL) has demonstrated that ventilated automotive seats not only can improve passenger comfort but also a vehicle's fuel economy. That's because ventilated seats keep drivers and passengers cooler, so they need less air conditioning to be comfortable. NREL's Vehicle Ancillary Loads Reduction team has been

  20. Secretary Chu Speaks at the 2010 Washington Auto Show

    ScienceCinema (OSTI)

    Secretary Chu

    2016-07-12

    Secretary Chu lays out a roadmap for how the U.S. can lead the world in making the clean vehicles we need at the 2010 Washington Auto Show. He also announced that the Department of Energy had closed on a $1.4 billion loan to Nissan to build the all-electric LEAF in Tennessee and create up to 1,300 American jobs.

  1. Modified Yeast Show Improved Xylose Fermentation and Toxin Tolerance -

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Energy Innovation Portal Show Improved Xylose Fermentation and Toxin Tolerance Great Lakes Bioenergy Research Center Contact GLBRC About This Technology Technology Marketing Summary Bleaching plant material with alkaline hydrogen peroxide (AHP) is an old process used for papermaking. Several decades ago researchers suggested that this method also could be used in biofuel production. The method involves treating switchgrass or corn stover with hydrogen peroxide under basic conditions.

  2. ORISE: Report shows nuclear engineering graduation rates leveling off in

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    2014 after five years of increase ORISE report shows nuclear engineering graduation rates leveling off in 2014 after five years of increase Decline seen in undergraduate and master degrees, while number of doctoral degrees awarded increased FOR IMMEDIATE RELEASE July 31, 2015 FY15-38 OAK RIDGE, Tenn.-The number of college students graduating with majors in nuclear engineering has flattened and even declined somewhat after five straight years of continual increases, according to a report by

  3. ORISE: Report shows number of health physics degrees for 2010

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    report shows number of health physics degrees increased for graduates, decreased for undergraduates in 2010 Decreased number of B.S. degrees remains higher than levels in the early 2000 FOR IMMEDIATE RELEASE Dec. 20, 2011 FY12-09 OAK RIDGE, Tenn.-The number of health physics graduate degrees increased for both master's and doctoral candidates in 2010, but decreased for bachelor's degrees, says a report released this year by the Oak Ridge Institute for Science and Education. The ORISE report,

  4. Secretary Chu Speaks at the 2010 Washington Auto Show

    SciTech Connect (OSTI)

    Secretary Chu

    2010-02-03

    Secretary Chu lays out a roadmap for how the U.S. can lead the world in making the clean vehicles we need at the 2010 Washington Auto Show. He also announced that the Department of Energy had closed on a $1.4 billion loan to Nissan to build the all-electric LEAF in Tennessee and create up to 1,300 American jobs.

  5. ORISE: Report shows nuclear engineering graduation rates rebounding in 2015

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    after brief decline report shows nuclear engineering graduation rates rebounding in 2015 after brief decline Increases seen in undergraduate and master degrees, while number of doctorate degrees awarded declined FOR IMMEDIATE RELEASE May 23, 2016 FY16-27 OAK RIDGE, Tenn.-After briefly declining in 2014 following five straight years of continual increases, the number of college students graduating with majors in nuclear engineering has rebounded. This is according to an annual study conducted

  6. NNSA administrator shows NM congressional delegation the Albuquerque

    National Nuclear Security Administration (NNSA)

    Complex to make case for new facility | National Nuclear Security Administration | (NNSA) administrator shows NM congressional delegation the Albuquerque Complex to make case for new facility Friday, February 26, 2016 - 1:42pm WASHINGTON, DC - Lt. Gen. Frank Klotz (Ret.), Administrator of the Department of Energy's National Nuclear Security Administration, hosted two members of the New Mexico congressional delegation on Feb. 18 for a tour of the aging facilities occupied by 1,200 NNSA

  7. Case Studies Show the Value of Program Evaluation

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    
 1
 Case Studies Show the Value of Program Evaluation Value of Program Evaluation Case Study Series Sponsored by the U.S. Department of Energy, November 2009 The U.S Department of Energy sponsored several small case studies that clearly demonstrate the benefits that evaluation can provide to energy and environmental programs. The result is a set of five "Value of Program Evaluation" Case Studies (each 2-pages in length) documenting the benefits of implementing recommendations from

  8. Perovskite solar technology shows quick energy returns | Argonne National

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Laboratory Perovskite solar technology shows quick energy returns By Payal Marathe * July 17, 2015 Tweet EmailPrint Solar panels are an investment-not only in terms of money, but also energy. It takes energy to mine, process and purify raw materials, and then to manufacture and install the final product. Silicon-based panels, which dominate the market for solar power, usually need about two years to return this energy investment. But for technology made with perovskites-a class of materials

  9. Kuwaiti oil sector shows more signs of recovery

    SciTech Connect (OSTI)

    Not Available

    1992-04-06

    This paper reports that Kuwait's oil sector continues to show signs of recovery from the Persian Gulf war. On Mar. 23 Kuwait Petroleum Co. (KPC) loaded the country's first shipment of liquefied petroleum gas for export since the Iraqi invasion in August 1990. In addition, the first shipment of Kuwaiti crude recovered from giant oil lakes formed by hundreds of wild wells sabotaged in the war was to arrive by tanker in Naples, Italy, late last month. The tanker is carrying 210,000 bbl of crude. However, the project to clean up the lakes and recover more oil, undertaken by Bechtel Corp. with Kuwait Oil Co. (KOC), has reached a stand still.

  10. Calculation notes that support accident scenario and consequence determination of a waste tank criticality

    SciTech Connect (OSTI)

    Crowe, R.D., Westinghouse Hanford

    1996-08-02

    The purpose of this calculation note is to provide the basis forcriticality consequences for the Tank Farm Safety Analysis Report(FSAR). Criticality scenario is developed and details and description of the analysis methods are provided.

  11. Calculation notes that support accident scenario and consequence of the evaporator dump

    SciTech Connect (OSTI)

    Crowe, R.D., Westinghouse Hanford

    1996-09-09

    The purpose of this calculation note is to provide the basis for evaporator dump consequence for the Tank Farm Safety Analysis Report (FSAR). Evaporator Dump scenario is developed and details and description of the analysis methods are provided.

  12. Calculation notes that support accident scenario and consequence of the evaporator dump

    SciTech Connect (OSTI)

    Crowe, R.D.

    1996-09-27

    The purpose of this calculation note is to provide the basis for evaporator dump consequence for the Tank Farm Safety Analysis Report (FSAR). Evaporator Dump scenario is developed and details and description of the analysis methods are provided.

  13. Calculation notes that support accident scenario and consequence determination of a waste tank criticality

    SciTech Connect (OSTI)

    Crowe, R.D.

    1996-09-27

    The purpose of this calculation note is to provide the basis for criticality consequences for the Tank Farm Safety Analysis Report (FSAR). Criticality scenario is developed and details and description of the analysis methods are provided.

  14. L3: RTM.MCH.P6.02 Technical Note RNSD-00-

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Oak Ridge National Laboratory April 5, 2013 CASL-U-2014-0083-000 Technical Note Reactor and Nuclear Systems Division Radiation Transport Group From: Tom Evans, Steven Hamilton ...

  15. Publisher's Note: New mechanism for the top-bottom mass hierarchy...

    Office of Scientific and Technical Information (OSTI)

    New mechanism for the top-bottom mass hierarchy Phys. Rev. D 70, 055006 (2004) Citation Details In-Document Search Title: Publisher's Note: New mechanism for the top-bottom mass ...

  16. Geothermal Industry Ends 2012 on a High Note | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Industry Ends 2012 on a High Note Geothermal Industry Ends 2012 on a High Note December 18, 2012 - 12:14pm Addthis Year-end highlights include new domestic projects, international development and policy benchmarks Washington, D.C. - The past 12 months saw continued economic challenges for many American industries, including those in the renewable energy field, but the country's geothermal community witnessed a year of growth, both domestically and abroad. The Geothermal Energy Association (GEA)

  17. A nanoparticle label/immunochromatographic electrochemical biosensor for rapid and sensitive detection of prostate-specific antigen

    SciTech Connect (OSTI)

    Lin, Ying-Ying; Wang, Jun; Liu, Guodong; Wu, Hong; Wai, Chien M.; Lin, Yuehe

    2008-06-15

    We present a nanoparticle (NP) label/immunochromatographic electrochemical biosensor (IEB) for rapid and sensitive detection of prostate-specific antigen (PSA) in human serum. This IEB integrates the immunochromatographic strip with the electrochemical detector for transducing quantitative signals. The NP label, made of CdSe@ZnS, serves as a signal-amplifier vehicle. A sandwich immunoreaction was performed on the immunochromatographic strip. The captured NP labels in the test zone were determined by highly sensitive stripping voltammetric measurement of the dissolved metallic component (cadmium) with a disposable-screen-printed electrode, which is embedded underneath the membrane of the test zone. Experimental parameters (e.g., immunoreaction time, the amount of anti-PSA-NP conjugations applied) and electrochemical detection conditions (e.g., preconcentration potential and time) were optimized using this biosensor for PSA detection. The analytical performance of this biosensor was evaluated with serum PSA samples according to the figure-of-merits (e.g., dynamic range, reproducibility, and detection limit). The results were validated with enzyme-linked immunosorbent assay (ELISA) and show high consistency. It is found that this biosensor is very sensitive with the detection limit of 0.02 ng/mL PSA and is quite reproducible. This method is rapid, clinically accurate, and less expensive than other diagnosis tools for PSA; therefore, this IEB coupled with a portable electrochemical analyzer shows great promise for simple, sensitive, quantitative point-of-care testing of disease-related protein biomarkers.

  18. Communication: Orientational self-ordering of spin-labeled cholesterol analogs in lipid bilayers in diluted conditions

    SciTech Connect (OSTI)

    Kardash, Maria E.; Dzuba, Sergei A.

    2014-12-07

    Lipid-cholesterol interactions are responsible for different properties of biological membranes including those determining formation in the membrane of spatial inhomogeneities (lipid rafts). To get new information on these interactions, electron spin echo (ESE) spectroscopy, which is a pulsed version of electron paramagnetic resonance (EPR), was applied to study 3β-doxyl-5α-cholestane (DCh), a spin-labeled analog of cholesterol, in phospholipid bilayer consisted of equimolecular mixture of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine and 1,2-dioleoyl-sn-glycero-3-phosphocholine. DCh concentration in the bilayer was between 0.1 mol.% and 4 mol.%. For comparison, a reference system containing a spin-labeled 5-doxyl-stearic acid (5-DSA) instead of DCh was studied as well. The effects of “instantaneous diffusion” in ESE decay and in echo-detected (ED) EPR spectra were explored for both systems. The reference system showed good agreement with the theoretical prediction for the model of spin labels of randomly distributed orientations, but the DCh system demonstrated remarkably smaller effects. The results were explained by assuming that neighboring DCh molecules are oriented in a correlative way. However, this correlation does not imply the formation of clusters of cholesterol molecules, because conventional continuous wave EPR spectra did not show the typical broadening due to aggregation of spin labels and the observed ESE decay was not faster than in the reference system. So the obtained data evidence that cholesterol molecules at low concentrations in biological membranes can interact via large distances of several nanometers which results in their orientational self-ordering.

  19. Sugarcane transgenics expressing MYB transcription factors show improved glucose release

    DOE PAGES-Beta [OSTI]

    Poovaiah, Charleson R.; Bewg, William P.; Lan, Wu; Ralph, John; Coleman, Heather D.

    2016-07-15

    In this study, sugarcane, a tropical C4 perennial crop, is capable of producing 30-100 tons or more of biomass per hectare annually. The lignocellulosic residue remaining after sugar extraction is currently underutilized and can provide a significant source of biomass for the production of second-generation bioethanol. As a result, MYB31 and MYB42 were cloned from maize and expressed in sugarcane with and without the UTR sequences. The cloned sequences were 98 and 99 % identical to the published nucleotide sequences. The inclusion of the UTR sequences did not affect any of the parameters tested. There was little difference in plantmore » height and the number of internodes of the MYB-overexpressing sugarcane plants when compared with controls. MYB transgene expression determined by qPCR exhibited continued expression in young and maturing internodes. MYB31 downregulated more genes within the lignin biosynthetic pathway than MYB42. MYB31 and MYB42 expression resulted in decreased lignin content in some lines. All MYB42 plants further analyzed showed significant increases in glucose release by enzymatic hydrolysis in 72 h, whereas only two MYB31 plants released more glucose than control plants. This correlated directly with a significant decrease in acid-insoluble lignin. Soluble sucrose content of the MYB42 transgenic plants did not vary compared to control plants. In conclusion, this study demonstrates the use of MYB transcription factors to improve the production of bioethanol from sugarcane bagasse remaining after sugar extraction.« less

  20. Note: O-ring stack system for electron gun alignment

    SciTech Connect (OSTI)

    Park, In-Yong; Cho, Boklae; Han, Cheolsu; Shin, Seungmin; Lee, Dongjun; Ahn, Sang Jung

    2015-01-15

    We present a reliable method for aligning an electron gun which consists of an electron source and lenses by controlling a stack of rubber O-rings in a vacuum condition. The beam direction angle is precisely tilted along two axes by adjusting the height difference of a stack of O-rings. In addition, the source position is shifted in each of three orthogonal directions. We show that the tilting angle and linear shift along the x and y axes as obtained from ten stacked O-rings are ±2.55° and ±2 mm, respectively. This study can easily be adapted to charged particle gun alignment and adjustments of the flange position in a vacuum, ensuring that its results can be useful with regard to electrical insulation between flanges with slight modifications.

  1. PHENIX WBS notes. Cost and schedule review copy

    SciTech Connect (OSTI)

    Not Available

    1994-02-01

    The Work Breakdown Structure (WBS) Book begins with this Overview section, which contains the high-level summary cost estimate, the cost profile, and the global construction schedule. The summary cost estimate shows the total US cost and the cost in terms of PHENIX construction funds for building the PHENIX detector. All costs in the WBS book are shown in FY 1993 dollars. Also shown are the institutional and foreign contributions, the level of pre-operations funding, and the cost of deferred items. Pie charts are presented at PHENIX WBS level 1 and 2 that show this information. The PHENIX construction funds are shown broken down to PHENIX WBS level 3 items per fiscal year, and the resulting profile is compared to the RHIC target profile. An accumulated difference of the two profiles is also shown. The PHENIX global construction schedule is presented at the end of the Overview section. Following the Overview are sections for each subsystem. Each subsystem section begins with a summary cost estimate, cost profile, and critical path. The total level 3 cost is broken down into fixed costs (M&S), engineering costs (EDIA) and labor costs. Costs are further broken down in terms of PHENIX construction funds, institutional and foreign contributions, pre-operations funding, and deferred items. Also shown is the contingency at level 3 and the level 4 breakdown of the total cost. The cost profile in fiscal years is shown at level 3. The subsystem summaries are followed by the full cost estimate and schedule sheets for that subsystem. These detailed sheets are typically carried down to level 7 or 8. The cost estimate Total, M&S, EDIA, and Labor breakdowns, as well as contingency, for each WBS entry.

  2. Thrombus detection using a Tc-99m labeled antifibrin monoclonal antibody (MoAb). Experiments in vitro and in animals

    SciTech Connect (OSTI)

    Wasser, M.N.; Pauwels, E.K.; Nieuwenhuizen, W. )

    1990-01-01

    This paper describes the production and characterization of an antifibrin monoclonal antibody, produced by immunizing mice with fibrinogen degradation fragment Y. The antibody (designated Y22) is directed against a conformation dependent epitope in the D-domain of fibrin Y22 was labeled with the radionuclide Tc-99m. Experiments in vitro and in rats are presented which show the potential of scintigraphic detection of thrombi with Tc-99m-Y22. Preliminary results show that immunoscintigraphy of thrombi may also have potential for the monitoring of thrombolytic therapy (eg with t-PA).

  3. Method for producing labeled single-stranded nucleic acid probes

    DOE Patents [OSTI]

    Dunn, John J.; Quesada, Mark A.; Randesi, Matthew

    1999-10-19

    Disclosed is a method for the introduction of unidirectional deletions in a cloned DNA segment. More specifically, the method comprises providing a recombinant DNA construct comprising a DNA segment of interest inserted in a cloning vector, the cloning vector having an f1 endonuclease recognition sequence adjacent to the insertion site of the DNA segment of interest. The recombinant DNA construct is then contacted with the protein pII encoded by gene II of phage f1 thereby generating a single-stranded nick. The nicked DNA is then contacted with E. coli Exonuclease III thereby expanding the single-stranded nick into a single-stranded gap. The single-stranded gapped DNA is then contacted with a single-strand-specific endonuclease thereby producing a linearized DNA molecule containing a double-stranded deletion corresponding in size to the single-stranded gap. The DNA treated in this manner is then incubated with DNA ligase under conditions appropriate for ligation. Also disclosed is a method for producing single-stranded DNA probes. In this embodiment, single-stranded gapped DNA, produced as described above, is contacted with a DNA polymerase in the presence of labeled nucleotides to fill in the gap. This DNA is then linearized by digestion with a restriction enzyme which cuts outside the DNA segment of interest. The product of this digestion is then denatured to produce a labeled single-stranded nucleic acid probe.

  4. A European Sustainable Tourism Labels proposal using a composite indicator

    SciTech Connect (OSTI)

    Blancas, Francisco Javier; Lozano-Oyola, Macarena; González, Mercedes

    2015-09-15

    The tourism sector in Europe faces important challenges which it must deal with to promote its future development. In this context, the European Commission considers that two key issues must be addressed. On the one hand, a better base of socio-economic knowledge about tourism and its relationship with the environment is needed, and, on the other hand, it is necessary to improve the image of European areas as quality sustainable tourism destinations. In this paper we present analytical tools that cover these needs. Specifically, we define a system of sustainable tourism indicators and we obtain a composite indicator incorporating weights quantified using a panel of experts. Employing the values of this global indicator as a basis, we define a Sustainable Tourism Country-Brand Ranking which assesses the perception of each country-brand depending on its degree of sustainability, and a system of sustainable tourism labels which reward the management carried out. - Highlights: • We define a system of indicators to improve the knowledge about sustainable tourism. • We obtain composite indicators based on expert knowledge. • The Sustainable Tourism Country-Brand Ranking would improve the image of destinations. • We define a Sustainable Tourism Labels System to assess country-brands. • The conclusions of the empirical analysis can be extrapolated to other tourist areas.

  5. International Experience in Standards and Labeling Programs for Rice Cookers

    SciTech Connect (OSTI)

    Zhou, Nan; Zheng, Nina

    2008-05-01

    China has had an active program on energy efficiency standards for household appliances since the mid-1990s. Rice cooker is among the first to be subject to such mandatory regulation, since it is one of the most prevalent electric appliances in Chinese households. Since first introduced in 1989, the minimum energy efficiency standard for rice cookers has not been revised. Therefore, the potential for energy saving is considerable. Initial analysis from CNIS indicates that potential carbon savings is likely to reach 7.6 million tons of CO2 by the 10th year of the standard implementation. Since September 2007, CNIS has been working with various groups to develop the new standard for rice cookers. With The Energy Foundation's support, LBNL has assisted CNIS in the revision of the minimum energy efficiency standard for rice cookers that is expected to be effective in 2009. Specifically, work has been in the following areas: assistance in developing consumer survey on usage pattern of rice cookers, review of international standards, review of international test procedures, comparison of the international standards and test procedures, and assessment of technical options of reducing energy use. This report particularly summarizes the findings of reviewing international standards and technical options of reducing energy consumption. The report consists of an overview of rice cooker standards and labeling programs and testing procedures in Hong Kong, South Korea, Japan and Thailand, and Japan's case study in developing energy efficiency rice cooker technologies and rice cooker efficiency programs. The results from the analysis can be summarized as the follows: Hong Kong has a Voluntary Energy Efficiency Labeling scheme for electric rice cookers initiated in 2001, with revision implemented in 2007; South Korea has both MEPS and Mandatory Energy Efficiency Label targeting the same category of rice cookers as Hong Kong; Thailand's voluntary endorsement labeling program is

  6. Preparation of 13C/15N-labeled oligomers using the polymerase chain reaction

    DOE Patents [OSTI]

    Chen, Xian; Gupta, Goutam; Bradbury, E. Morton

    2001-01-01

    Preparation of .sup.13 C/.sup.15 N-labeled DNA oligomers using the polymerase chain reaction (PCR). A PCR based method for uniform (.sup.13 C/.sup.15 N)-labeling of DNA duplexes is described. Multiple copies of a blunt-ended duplex are cloned into a plasmid, each copy containing the sequence of interest and restriction Hinc II sequences at both the 5' and 3' ends. PCR using bi-directional primers and uniformly .sup.13 C/.sup.15 N-labeled dNTP precursors generates labeled DNA duplexes containing multiple copies of the sequence of interest. Twenty-four cycles of PCR, followed by restriction and purification, gave the uniformly .sup.13 C/.sup.15 N-labeled duplex sequence with a 30% yield. Such labeled duplexes find significant applications in multinuclear magnetic resonance spectroscopy.

  7. Document clustering methods, document cluster label disambiguation methods, document clustering apparatuses, and articles of manufacture

    DOE Patents [OSTI]

    Sanfilippo, Antonio; Calapristi, Augustin J.; Crow, Vernon L.; Hetzler, Elizabeth G.; Turner, Alan E.

    2009-12-22

    Document clustering methods, document cluster label disambiguation methods, document clustering apparatuses, and articles of manufacture are described. In one aspect, a document clustering method includes providing a document set comprising a plurality of documents, providing a cluster comprising a subset of the documents of the document set, using a plurality of terms of the documents, providing a cluster label indicative of subject matter content of the documents of the cluster, wherein the cluster label comprises a plurality of word senses, and selecting one of the word senses of the cluster label.

  8. OPS 9.18 Equipment and Piping Labeling 8/24/98 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    8 Equipment and Piping Labeling 8/24/98 OPS 9.18 Equipment and Piping Labeling 8/24/98 The objective of this surveillance is to verify that facility equipment and piping are labeled in a manner such that facility personnel are able to positively identify equipment they operate. This surveillance provides a basis for evaluating the effectiveness of the contractor's program for labeling equipment and piping and for establishing compliance with DOE requirements. OPS9-18.doc (31.5 KB) More Documents

  9. Show Tips

    Energy.gov [DOE]

    These guidelines are designed to help you prepare for exhibiting. Be sure that you are fully prepared before the event begins.

  10. Automatic Labeling for Entity Extraction in Cyber Security

    SciTech Connect (OSTI)

    Bridges, Robert A; Jones, Corinne L; Iannacone, Michael D; Testa, Kelly M; Goodall, John R

    2014-01-01

    Timely analysis of cyber-security information necessitates automated information extraction from unstructured text. While state-of-the-art extraction methods produce extremely accurate results, they require ample training data, which is generally unavailable for specialized applications, such as detecting security related entities; moreover, manual annotation of corpora is very costly and often not a viable solution. In response, we develop a very precise method to automatically label text from several data sources by leveraging related, domain-specific, structured data and provide public access to a corpus annotated with cyber-security entities. Next, we implement a Maximum Entropy Model trained with the average perceptron on a portion of our corpus (~750,000 words) and achieve near perfect precision, recall, and accuracy, with training times under 17 seconds.

  11. Samsung recalls 1M Samsung Galazy Note 7 phones > EMC2 News > The Energy

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Materials Center at Cornell Samsung recalls 1M Samsung Galazy Note 7 phones September 15th, 2016 › Jon Swartz, USA TODAY 8:48 p.m. EDT September 15, 2016 SAN FRANCISCO - Samsung has officially recalled 1 million of its Galaxy Note 7 phones sold before Sept. 15 because of "serious fire and burn hazards." The electronics giant made the announcement during a conference call with the U.S. Consumer Product Safety Commission late Thursday. Samsung says it received 92 reports of

  12. A note from Howard H. Baker, Jr. | Y-12 National Security Complex

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    A note from Howard H. ... A note from Howard H. Baker, Jr. Posted: February 11, 2013 - 3:49pm | Y-12 Report | Volume 9, Issue 2 | 2013 "I remember visiting Oak Ridge at the height of its construction. The town had grown up out of corn fields in super secrecy. My dad and I didn't know its purpose, but we knew it involved important, vital work. That vitally important work continues today. For 70 years Y-12, in particular, has served the nation as a reservoir of talent and insight. The very

  13. Nucleic acid analysis using terminal-phosphate-labeled nucleotides

    DOE Patents [OSTI]

    Korlach, Jonas; Webb, Watt W.; Levene, Michael; Turner, Stephen; Craighead, Harold G.; Foquet, Mathieu

    2008-04-22

    The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined.

  14. Radiological Contamination Control Training for Laboratory Research

    Energy Savers

    ... Show appropriate labels, tape, etc. Discuss consequences if radiation label is found in municipal waste stream. DOE-HDBK-1106-97 21 Lesson Plan Instructor's Notes 2. Penetration ...

  15. Temperature-induced labelling of Fluo-3 AM selectively yields brighter nucleus in adherent cells

    SciTech Connect (OSTI)

    Meng, Guixian; Pan, Leiting; Li, Cunbo; Hu, Fen; Shi, Xuechen; Lee, Imshik; Drevenšek-Olenik, Irena; Zhang, Xinzheng; Xu, Jingjun

    2014-01-17

    Highlights: •We detailedly examine temperature effects of Fluo-3 AM labelling in adherent cells. •4 °C Loading and 20 °C de-esterification of Fluo-3 AM yields brighter nuclei. •Brighter nuclei labelling by Fluo-3 AM also depends on cell adhesion quality. •A qualitative model of the brighter nucleus is proposed. -- Abstract: Fluo-3 is widely used to study cell calcium. Two traditional approaches: (1) direct injection and (2) Fluo-3 acetoxymethyl ester (AM) loading, often bring conflicting results in cytoplasmic calcium ([Ca{sup 2+}]{sub c}) and nuclear calcium ([Ca{sup 2+}]{sub n}) imaging. AM loading usually yields a darker nucleus than in cytoplasm, while direct injection always induces a brighter nucleus which is more responsive to [Ca{sup 2+}]{sub n} detection. In this work, we detailedly investigated the effects of loading and de-esterification temperatures on the fluorescence intensity of Fluo-3 in response to [Ca{sup 2+}]{sub n} and [Ca{sup 2+}]{sub c} in adherent cells, including osteoblast, HeLa and BV2 cells. Interestingly, it showed that fluorescence intensity of nucleus in osteoblast cells was about two times larger than that of cytoplasm when cells were loaded with Fluo-3 AM at 4 °C and allowed a subsequent step for de-esterification at 20 °C. Brighter nuclei were also acquired in HeLa and BV2 cells using the same experimental condition. Furthermore, loading time and adhesion quality of cells had effect on fluorescence intensity. Taken together, cold loading and room temperature de-esterification treatment of Fluo-3 AM selectively yielded brighter nucleus in adherent cells.

  16. OTS NOTE

    Office of Legacy Management (LM)

    2, 1990 TO: W. Alexander Williams FROM: Don Mackenzie &d> SUBJECT: Elimination of 3 Facilities from FUSRAP Enclosed are elimination recommendations for Vitro Chemical Co.,...

  17. OTS NOTE

    Office of Legacy Management (LM)

    January 15, 1991 TO: Alexander Williams FROM: Dan Stout@ SUBJECT: Gruen Watch Company Consideration Recommendation Attached for your review is a consideration recommendation for...

  18. Explanatory Notes

    U.S. Energy Information Administration (EIA) (indexed site)

    data at a State level on 14 petroleum products for various retail and wholesale marketing categories. The Form EIA-782B collects resellerretailer monthly price and volume...

  19. EDITORS NOTE:

    Office of Environmental Management (EM)

    ... and accelerating dismantlement of the Cold War stockpile. * Transform the current ... to advance the knowledge of plasma and fusion energy sciences to the point where a ...

  20. OTS NOTE

    Office of Legacy Management (LM)

    The attached memorandum and supporting documents are the basis for our recommendation to ... No documents have been discovered to date which specifically indicate use or handling of ...

  1. OTS NOTE

    Office of Legacy Management (LM)

    The attached memorandum and supporting documents are the basis for our recommendation to ... Documents discovered to date indicating use or handling of radioactive material by the ...

  2. OTS NOTE

    Office of Legacy Management (LM)

    The attached memorandum and supporting documents are the basis for our recommendation to ... Documents discovered to date indicating use or handling of radioactive material by ...

  3. OTS NOTE

    Office of Legacy Management (LM)

    ... It is proposed that the Commission pay 4. 50 per pound of contained uranium oxide (U3C31, such pay- .ment to be in addition to a price, f. o. b. Chattanooga, TZM. , of 4. 25 per ...

  4. Explanatory Notes

    U.S. Energy Information Administration (EIA) (indexed site)

    complete enumera- tion has the same nonsampling errors as the sample survey. The sampling error, or standard error of the estimate, is a measure of the variability among the...

  5. OTS NOTE

    Office of Legacy Management (LM)

    FUSRAP NJ.18 Exxon Research and Engineering Company The Former Standard Oil Development Company Linden, New Jersey Site Function In the spring of 1942, Standard Oil Development ...

  6. Preparation and immunoreactivity of high specific activity indium-111-DTPA labeled monoclonal antibody (MoAb) using ultrapure indium-111

    SciTech Connect (OSTI)

    Zoghbi, S.S.; Neumann, R.D.; Gottschalk, A.

    1986-10-01

    The preparation of high-specific activity /sup 111/In-DTPA-MoAb without increasing the number of DTPA molecules per Ab was investigated. Instant thin layer chromatography was used to assay the relationship between labeling efficiencies and specific activities. With ultrapurified /sup 111/In, the specific activity of the radiolabeled MoAb approached the expected theoretic maximum of 100 muCi/microgram. The bioactivity of such high-specific activity preparation showed no degradation as measured by in vitro cell binding assay.

  7. Synthesis and evaluation of radioactive and fluorescent residualizing labels for identifying sites of plasma protein catabolism

    SciTech Connect (OSTI)

    Maxwell, J.L.; Baynes, J.W.; Thorpe, S.R.

    1986-05-01

    Inulin and lactose were each coupled to tyramine by reductive amination with NaBH/sub 3/CN and the tyramine then labeled with /sup 125/I. Dilactitol-/sup 125/I-tyramine (DLT) and inulin-/sup 125/I-tyramine (InTn) were coupled by reductive amination and cyanuric chloride, respectively, to asialofetuin (ASF), fetuin and rat serum albumin (RSA). Attachment of either label had no effect on the circulating half-lives of the proteins. Radioactivity from labeled ASF was recovered in rat liver (> 90%) by 1 h post-injection and remained in liver with half-lives of 2 and 6 days, respectively, for the DLT and InTn labels. Whole body recoveries of radioactivity from DLT- and InTn labels. Whole body recoveries of radioactivity from DLT- and InTn-labeled RSA were 5 and 6.5 days, respectively, again indicating that the larger glycoconjugate label residualized more efficiently in cells following protein degradation. (Lactitol)/sub 2/-N-CH/sub 2/-CH/sub 2/-NH-fluroescein (DLF) was also coupled to ASF by reductive amination and recovered quantitatively in liver at 1 h post-injection. Native ASF was an effective competitor for clearance of DLF-ASF from the circulation. Fluorescent degradation products were retained in liver with a half-life of 1.2 days. Residualizing fluorescent labels should be useful for identification and sorting of cells active in the degradation of plasma proteins.

  8. Compliance and Verification of Standards and Labeling Programs in China: Lessons Learned

    SciTech Connect (OSTI)

    Saheb, Yamina; Zhou, Nan; Fridley, David; Pierrot, Andre

    2010-08-01

    After implementing several energy efficiency standards and labels (30 products covered by MEPS, 50 products covered by voluntary labels and 19 products by mandatory labels), the China National Institute of Standardization (CNIS) is now implementing verification and compliance mechanism to ensure that the energy information of labeled products comply with the requirements of their labels. CNIS is doing so by organizing check testing on a random basis for room air-conditioners, refrigerators, motors, heaters, computer displays, ovens, and self -ballasted lamps. The purpose of the check testing is to understand the implementation of the Chinese labeling scheme and help local authorities establishing effective compliance mechanisms. In addition, to ensure robustness and consistency of testing results, CNIS has coordinated a round robin testing for room air conditioners. Eight laboratories (Chinese (6), Australian (1) and Japanese (1)) have been involved in the round robin testing and tests were performed on four sets of samples selected from manufacturer's production line. This paper describes the methodology used in undertaking both check and round robin testing, provides analysis of testing results and reports on the findings. The analysis of both check and round robin testing demonstrated the benefits of a regularized verification and monitoring system for both laboratories and products such as (i) identifying the possible deviations between laboratories to correct them, (ii) improving the quality of testing facilities, (iii) ensuring the accuracy and reliability of energy label information in order to strength the social credibility of the labeling program and the enforcement mechanism in place.

  9. Compliance and Verification of Standards and Labelling Programs in China: Lessons Learned

    SciTech Connect (OSTI)

    Saheb, Yamina; Zhou, Nan; Fridley, David; Pierrot, Andr

    2010-06-11

    After implementing several energy efficiency standards and labels (30 products covered by MEPS, 50 products covered by voluntary labels and 19 products by mandatory labels), the China National Institute of Standardization (CNIS) is now implementing verification and compliance mechanism to ensure that the energy information of labeled products comply with the requirements of their labels. CNIS is doing so by organizing check testing on a random basis for room air-conditioners, refrigerators, motors, heaters, computer displays, ovens, and self -ballasted lamps. The purpose of the check testing is to understand the implementation of the Chinese labeling scheme and help local authorities establishing effective compliance mechanisms. In addition, to ensure robustness and consistency of testing results, CNIS has coordinated a round robin testing for room air conditioners. Eight laboratories (Chinese (6), Australian (1) and Japanese (1)) have been involved in the round robin testing and tests were performed on four sets of samples selected from manufacturer?s production line. This paper describes the methodology used in undertaking both check and round robin testing, provides analysis of testing results and reports on the findings. The analysis of both check and round robin testing demonstrated the benefits of a regularized verification and monitoring system for both laboratories and products such as (i) identifying the possible deviations between laboratories to correct them, (ii) improving the quality of testing facilities, (iii) ensuring the accuracy and reliability of energy label information in order to strength the social credibility of the labeling program and the enforcement mechanism in place.

  10. Regular oscillations and random motion of glass microspheres levitated by a single optical beam in air: Publisher’s note

    DOE PAGES-Beta [OSTI]

    Moore, Jeremy; Martin, Leopoldo L.; Maayani, Shai; Kim, Kyu Hyun; Chandrahalim, Hengky; Eichenfield, Matt; Martin, Inocencio R.; Carmon, Tal

    2016-02-19

    The publisher’s note amends a recent publication [Opt. Express 24(3), 2850–2857 (2016)] to include Acknowledgments.

  11. Microsoft PowerPoint - DOE O 413 3B Brief v9 with key points in notes

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    [Read-Only] | Department of Energy DOE O 413 3B Brief v9 with key points in notes [Read-Only] Microsoft PowerPoint - DOE O 413 3B Brief v9 with key points in notes [Read-Only] Microsoft PowerPoint - DOE O 413 3B Brief v9 with key points in notes [Read-Only] (2.08 MB) More Documents & Publications Microsoft PowerPoint - DOE O 413 3B Brief v9 with key points in notes [Read-Only] CD-2, Approve Performance Baseline External Independent Review (EIR) Standard Operating Procedure (SOP)

  12. Label-free functional nucleic acid sensors for detecting target agents

    DOE Patents [OSTI]

    Lu, Yi; Xiang, Yu

    2015-01-13

    A general methodology to design label-free fluorescent functional nucleic acid sensors using a vacant site approach and an abasic site approach is described. In one example, a method for designing label-free fluorescent functional nucleic acid sensors (e.g., those that include a DNAzyme, aptamer or aptazyme) that have a tunable dynamic range through the introduction of an abasic site (e.g., dSpacer) or a vacant site into the functional nucleic acids. Also provided is a general method for designing label-free fluorescent aptamer sensors based on the regulation of malachite green (MG) fluorescence. A general method for designing label-free fluorescent catalytic and molecular beacons (CAMBs) is also provided. The methods demonstrated here can be used to design many other label-free fluorescent sensors to detect a wide range of analytes. Sensors and methods of using the disclosed sensors are also provided.

  13. Workshop Notes from ""Compressed Natural Gas and Hydrogen Fuels: Lessons Learned for the Safe Deployment of Vehicles"" Workshop, December 10-11, 2009

    Office of Energy Efficiency and Renewable Energy (EERE)

    These notes provide information about the Compressed Natural Gas and Hydrogen Fuels workshop in December 2009.

  14. Enhanced detection of fluorescence quenching in labeled cells

    DOE Patents [OSTI]

    Crissman, H.A.; Steinkamp, J.A.

    1987-11-30

    A method is provided for quantifying BrdU labeled DNA in cells. The BrdU is substituted onto the DNA and the DNA is stained with a first fluorochrome having a fluorescence which is quenchable by BrdU. The first fluorochrome is preferably a thymidine base halogen analogue, such as a Hoechst fluorochrome. The DNA is then stained with a second fluorochrome having a fluorescence which is substantially uneffected by BrdU. The second fluorochrome may be selected from the group consisting of mithramycin, chromomycin A3, olivomycin, propidium iodide and ethidium bromine. The fluorescence from the first and second fluorochromes is then measured to obtain first and second output signals, respectively. The first output signal is subtracted from the second output signal to obtain a difference signal which is functionally related to the quantity of BrdU incorporated into DNA. The technique is particularly useful for quantifying the synthesis of DNA during the S-phase of the cell cycle. 2 figs.

  15. Enhanced detection of fluorescence quenching in labeled cells

    DOE Patents [OSTI]

    Crissman, Harry A.; Steinkamp, John A.

    1992-01-01

    A method is provided for quantifying BrdU labeled DNA in cells. The BrdU is incorporated into the DNA and the DNA is stained with a first fluorochrome having a fluorescence which is quenchable by BrdU. The first fluorochrome is preferably a thymidine base halogen analogue, such as a Hoechst fluorochrome. The DNA is then stained with a second fluorochrome having a fluorescence that is substantially uneffected by BrdU. The second fluorochrome may be selected from the group consisting of mithramycin, chromomycin A3, olivomycin, propidium iodide and ethidium bromine. The fluorescence from the first and second fluorochromes is then measured to obtain first and second output signals, respectively. The first output signal is substracted from the second output signal to obtain a difference signal which is functionally related to the quantity of BrdU incorporated into DNA. The technique is particularly useful for quantifying the synthesis of DNA during the S-phase of the cell cycle.

  16. Synthesis and preliminary biological evaluations of fluorescent or 149Promethium labeled Trastuzumab-polyethylenimine

    DOE PAGES-Beta [OSTI]

    Fitzsimmons, Jonathan; Nayak, Tapan; Cutler, Cathy; Atcher, Robert

    2015-12-30

    Radioimmunotherapy utilize a targeting antibody coupled to a therapeutic isotope to target and treat a tumor or disease. In this study we examine the synthesis and cell binding of a polymer scaffold containing a radiotherapeutic isotope and a targeting antibody. Methods: The multistep synthesis of a fluorescent or 149Promethium-labeled Trastuzumab-polyethyleneimine (PEI), Trastuzumab, or PEI is described. In vitro uptake, internalization and/or the binding affinity to the Her2/neu expressing human breast adenocarcinoma SKBr3 cells was investigated with the labeled compounds. Fluorescent-labeled Trastuzumab-PEI was internalized more into cells at 2 and 18 h than fluorescent-labeled Trastuzumab or PEI. The fluorescent-labeled Trastuzumab wasmore » concentrated on the cell surface at 2 and 18 h and the labeled PEI had minimal uptake. DOTA-PEI was prepared and contained an average of 16 chelates per PEI; the compound was radio-labeled with 149Promethium and conjugated to Trastuzumab. The purified 149Pm-DOTA-PEI-Trastuzumab had a radiochemical purity of 96.7% and a specific activity of 0.118 TBq/g. The compound demonstrated a dissociation constant for the Her2/neu receptor of 20.30 ± 6.91 nM. In conclusion, the results indicate the DOTA-PEI-Trastuzumab compound has potential as a targeted therapeutic carrier, and future in vivo studies should be performed.« less

  17. A New Generation of Labels for a New Generation of Cars | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Energy A New Generation of Labels for a New Generation of Cars A New Generation of Labels for a New Generation of Cars May 25, 2011 - 5:42pm Addthis A New Generation of Labels for a New Generation of Cars John Schueler John Schueler Former New Media Specialist, Office of Public Affairs What does this mean for me? An improved car buying experience Clear cut cost comparisons of vehicles If you've ever gone through the process of shopping for a new car, you know just how difficult it can be to

  18. Procedures for reduction of Fe XII 10747 A coronal emission-line polarization observations. Technical note

    SciTech Connect (OSTI)

    Arnaud, J.; Newkirk, G.

    1987-01-01

    The note documents the reducing procedures used to obtain the best estimates of the coronal Stokes parameters from the raw measurements recorded in two spectral channels with the High Altitude Observatory-Sacramento Peak Observatory Coronal Emission-line Polarimeter (KELP). The original reduction programs were modified to survey the KELP data as a whole and to help determine whether corrections are needed for each scan.

  19. LLW (Low-Level Waste) Notes, Volume 13, Number 1, February 1998

    SciTech Connect (OSTI)

    1998-02-01

    LLW Notes is a newsletter distributed to Low-Level Radioactive Waste Forum Participants and other state and compact officials. The LLW Forum provides an opportunity for state and compact officials to share information with one another and to exchange views with officials of federal agencies and other interested parties. This issue focuses on the following topics: DOI approves Ward Valley permit application; Project evidentiary hearings begin in Texas; and Summary judgment motions in California breach of contract action.

  20. COLLOQUIUM - NOTE SPECIAL TIME OF 3:15PM: Savannah River National

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Laboratory: Underpinning Critical National Missions | Princeton Plasma Physics Lab May 15, 2013, 3:15pm to 5:30pm Colloquia MBG Auditorium COLLOQUIUM - NOTE SPECIAL TIME OF 3:15PM: Savannah River National Laboratory: Underpinning Critical National Missions Dr. Jeff Griffin Savannah River National Laboratory The Cold War mission of the Savannah River Site in South Carolina was to produce nuclear materials for the national defense. Since the Cold War ended, SRS has continued to ensure United

  1. COLLOQUIUM - PLEASE NOTE SPECIAL DATE/TIME: The Magnetospheric MultiScale

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Mission Investigation of Magnetic Reconnection | Princeton Plasma Physics Lab February 21, 2013, 10:30am to 12:00pm Colloquia MBG Auditorium COLLOQUIUM - PLEASE NOTE SPECIAL DATE/TIME: The Magnetospheric MultiScale Mission Investigation of Magnetic Reconnection Professor Roy Torbert University of New Hampshire Presentation: File TC21FEB2013_RBTorbert_COMPRESSED.pptx In late fall 2014, NASA will launch the Magnetospheric Multiscale (MMS) mission to study the kinetic physics of magnetic

  2. EPICS release 3.11.6 specific documentation -- Release notes for EPICS 3.11.6

    SciTech Connect (OSTI)

    1994-06-07

    These notes cover the following: (1) directions for switching to production APS release R3.11.6; (2) unbundling of channel access clients; (3) access security; (4) channel access additions; synchronous time support; and (5) description of major differences between R3.11.3 and R3.11.6 Also included is a list of new and/or updated documentation for the program.

  3. Specific uptake, dissociation, and degradation of /sup 125/I-labeled insulin in isolated turtle (Chrysemys dorbigni) thyroid glands

    SciTech Connect (OSTI)

    Marques, M.; da Silva, R.S.; Turyn, D.; Dellacha, J.M.

    1985-11-01

    Thyroid glands from turtles (Chrysemys dorbigni) pretreated with potassium iodide were incubated with /sup 125/I-insulin in the presence or absence of unlabeled insulin, in order to study its specific uptake. At 24 degrees, the specific uptake reached a plateau at 180 min of incubation. The dose of bovine insulin that inhibited 50% of the /sup 125/I-insulin uptake was 2 micrograms/ml of incubation medium. Most of the radioactive material (71%) extracted from the gland, after 30 min incubation with /sup 125/I-insulin, eluted in the same position as labeled insulin on Sephadex G-50. Only 24% eluted in the salt position. After 240 min incubation, increased amount of radioactivity appeared in the Na/sup 125/I position. When bovine insulin was added together with the labeled hormone, a substantial reduction of radioactivity was observed in the insulin and Na/sup 125/I elution positions. Dissociation studies were performed at 6 degrees in glands preincubated with /sup 125/I-insulin either at 24 or 6 degrees. The percentage of trichloroacetic acid (TCA)-soluble radioactive material in the dissociation medium increased with incubation time at both temperatures. However, the degradation activity was lower at 6 than at 24 degrees. The addition of bovine insulin to the incubation buffer containing /sup 125/I-insulin reduced the radioactive degradation products in the dissociated medium. Chloroquine or bacitracin inhibited the degradation activity. Incubation of thyroid glands with /sup 125/I-hGH or /sup 125/I-BSA showed values of uptake, dissociation, and degradation similar to those experiments in which an excess of bovine insulin was added together with the labeled hormone. Thus, by multiple criteria, such as specific uptake, dissociation, and degradation, the presence of insulin-binding sites in the turtle thyroid gland may be suggested.

  4. Energy Department Sets Tougher Standards for Clothes Washers to Qualify for the ENERGY STAR® Label

    Energy.gov [DOE]

    WASHINGTON, DC - The U.S. Department of Energy (DOE) today announced tougher standards for clothes washers to qualify for the ENERGY STAR® label, which lets American families identify which clothes...

  5. Look at the label and indicate the type of unit for which you...

    U.S. Energy Information Administration (EIA) (indexed site)

    Case Label Here STEP 1 STEP 2 Please provide the following information for the person who completed this form. (Use each box for individual letters, numbers, characters, or spaces. ...

  6. Look at the label and indicate the type of unit for which you...

    U.S. Energy Information Administration (EIA) (indexed site)

    Department of Energy Washington, DC 20585 Case Label Here STEP 1 STEP 2 Please provide ... C O M STEP 3 Reporting format: Report the requested information on this form, or in a ...

  7. DOE Withdraws the Energy Star Label from 34 Compact Fluorescent Light Bulbs

    Energy.gov [DOE]

    Washington, DC - On January 25th, the General Counsel notified 25 manufacturers that the Department of Energy has withdrawn their right to use the Energy Star label on 34 different models of...

  8. Department of Energy to Take Steps to Remove ENERGY STAR Label...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    As a result, effective January 2, 2010, certain LG French-door refrigerators are no longer eligible to carry the ENERGY STAR label. ENERGY STAR is a voluntary program sponsored ...

  9. Method for rapid base sequencing in DNA and RNA with two base labeling

    DOE Patents [OSTI]

    Jett, J.H.; Keller, R.A.; Martin, J.C.; Posner, R.G.; Marrone, B.L.; Hammond, M.L.; Simpson, D.J.

    1995-04-11

    A method is described for rapid-base sequencing in DNA and RNA with two-base labeling and employing fluorescent detection of single molecules at two wavelengths. Bases modified to accept fluorescent labels are used to replicate a single DNA or RNA strand to be sequenced. The bases are then sequentially cleaved from the replicated strand, excited with a chosen spectrum of electromagnetic radiation, and the fluorescence from individual, tagged bases detected in the order of cleavage from the strand. 4 figures.

  10. Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels

    DOE Patents [OSTI]

    Glazer, A.N.; Mathies, R.A.; Hung, S.C.; Ju, J.

    1998-12-29

    Cyanine dyes are used as the donor fluorophore in energy transfer labels in which light energy is absorbed by a donor fluorophore and transferred to an acceptor fluorophore which responds to the transfer by emitting fluorescent light for detection. The cyanine dyes impart an unusually high sensitivity to the labels thereby improving their usefulness in a wide variety of biochemical procedures, particularly nucleic acid sequencing, nucleic acid fragment sizing, and related procedures. 22 figs.

  11. Method for rapid base sequencing in DNA and RNA with two base labeling

    DOE Patents [OSTI]

    Jett, James H.; Keller, Richard A.; Martin, John C.; Posner, Richard G.; Marrone, Babetta L.; Hammond, Mark L.; Simpson, Daniel J.

    1995-01-01

    Method for rapid-base sequencing in DNA and RNA with two-base labeling and employing fluorescent detection of single molecules at two wavelengths. Bases modified to accept fluorescent labels are used to replicate a single DNA or RNA strand to be sequenced. The bases are then sequentially cleaved from the replicated strand, excited with a chosen spectrum of electromagnetic radiation, and the fluorescence from individual, tagged bases detected in the order of cleavage from the strand.

  12. Synthesis of isotopically labeled R- or S-[.sup.13C, .sup.2H] glycerols

    DOE Patents [OSTI]

    Martinez, Rodolfo A.; Unkefer, Clifford J.; Alvarez, Marc A.

    2008-01-22

    The present invention is directed to asymmetric chiral labeled glycerols including at least one chiral atom, from one to two .sup.13C atoms and from zero to four deuterium atoms bonded directly to a carbon atom, e.g., (2S) [1,2-.sup.13C.sub.2]glycerol and (2R) [1,2-.sup.13C.sub.2]glycerol, and to the use of such chiral glycerols in the preparation of labeled amino acids.

  13. Microsoft Word - Smart Grid Certification and Labeling Program 09-11-2009 _3_.docx

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    NETL Modern Grid Strategy Powering our 21st-Century Economy SMART GRID CERTIFICATION AND LABELING Conducted by National Energy Technology Laboratory for the U.S. Department of Energy Office of Electricity Delivery and Energy Reliability September 2009 Office of Electricity Delivery and Energy Reliability Smart Grid Certification and Labeling 1 DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor

  14. Methods of sequencing and detection using energy transfer labels with cyanine dyes as donor chromophores

    DOE Patents [OSTI]

    Glazer, Alexander N.; Mathies, Richard A.; Hung, Su-Chun; Ju, Jingyue

    2000-01-01

    Cyanine dyes are used as the donor fluorophore in energy transfer labels in which light energy is absorbed by a donor fluorophore and transferred to an acceptor fluorophore which responds to the transfer by emitting fluorescent light for detection. The cyanine dyes impart an unusually high sensitivity to the labels thereby improving their usefulness in a wide variety of biochemical procedures, particularly nucleic acid sequencing, nucleic acid fragment sizing, and related procedures.

  15. Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels

    DOE Patents [OSTI]

    Glazer, Alexander N.; Mathies, Richard A.; Hung, Su-Chun; Ju, Jingyue

    1998-01-01

    Cyanine dyes are used as the donor fluorophore in energy transfer labels in which light energy is absorbed by a donor fluorophore and transferred to an acceptor fluorophore which responds to the transfer by emitting fluorescent light for detection. The cyanine dyes impart an unusually high sensitivity to the labels thereby improving their usefulness in a wide variety of biochemical procedures, particularly nucleic acid sequencing, nucleic acid fragment sizing, and related procedures.

  16. Compositions for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R.; Petric, Andrej; Satyamurthy, Nagichettiar; Small, Gary W.; Cole, Gregory M.; Huang, Sung-Cheng

    2008-03-11

    Compositions useful for labeling .beta.-amyloid plaques and neurofibrillary tangles are provided. The compositions comprises compounds of formula (I): ##STR00001## wherein R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2-alkyl, --C.dbd.C(CN).sub.2-alkylenyl-R.sub.4, ##STR00002## wherein R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5 is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 and --C(O)NH.sub.2; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S; and R.sub.2 is selected from the group consisting of alkyl and alkylenyl-R.sub.10 and R.sub.3 is alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal, and spiperone-3-yl, or R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl, and further wherein one or more of the hydrogen, halogen or carbon atoms are optionally replaced with a radiolabel.

  17. Methods for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R.; Petric, Andrej; Satyamurthy, Nagichettiar; Small, Gary W.; Cole, Gregory M.; Huang, Sung-Cheng

    2001-01-01

    A method for labeling .beta.-amyloid plaques and neurofibrillary tangles in vivo and in vitro, comprises contacting a compound of formula (I): ##STR1## with mammalian tissue. In formula (I), R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2 -alkyl, --C.dbd.C(CN).sub.2 -alkylenyl-R.sub.4 , ##STR2## R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5, is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4 ; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH , --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 ; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S. R.sub.2 and R.sub.3 are each independently selected from the group consisting of alkyl and alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal and spiperone-3-yl. Alternatively, R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkylenyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl. In the compounds of formula (I), one or more of the hydrogen, halogen or carbon atoms can, optionally, be replaced with a radiolabel.

  18. Methods for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R.; Petric, Andrej; Satyamurthy, Nagichettiar; Small, Gary W.; Cole, Gregory M.; Huang, Sung-Cheng

    2003-12-09

    A method for labeling .beta.-amyloid plaques and neurofibrillary tangles in vivo and in vitro, comprises contacting a compound of formula (I): ##STR1## with mammalian tissue. In formula (I), R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2 -alkyl, --C.dbd.C(CN).sub.2 -alkylenyl-R.sub.4, ##STR2## R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5 is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4 ; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH, --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 ; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S. R.sub.2 and R.sub.3 are each independently selected from the group consisting of alkyl and alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal and spiperone-3-yl. Alternatively, R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkylenyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl. In the compounds of formula (I), one or more of the hydrogen, halogen or carbon atoms can, optionally, be replaced with a radiolabel.

  19. Note: Rapid reduction of graphene oxide paper by glow discharge plasma

    SciTech Connect (OSTI)

    Bo, Zheng; Qian, Jiajing; Duan, Liangping; Qiu, Kunzan Yan, Jianhua; Cen, Kefa; Han, Zhao Jun; Ostrikov, Kostya

    2015-05-15

    This note reports on a novel method for the rapid reduction of graphene oxide (GO) paper using a glow discharge plasma reactor. Glow discharge is produced and sustained between two parallel-plate graphite electrodes at a pressure of 240 mTorr. By exposing GO paper at the junction of negative-glow and Faraday-dark area for 4 min, the oxygen-containing groups can be effectively removed (C/O ratio increases from 2.6 to 7.9), while the material integrality and flexibility are kept well. Electrochemical measurements demonstrate that the as-obtained reduced GO paper can be potentially used for supercapacitor application.

  20. Note: Design principles of a linear array multi-channel effusive metal-vapor atom source

    SciTech Connect (OSTI)

    Jana, B.; Majumder, A.; Thakur, K. B.; Das, A. K.

    2013-10-15

    Atomic beams can easily be produced by allowing atoms to effuse through a channel. In an earlier investigation [A. Majumder et al., Vacuum 83, 989 (2009)], we had designed, fabricated, and characterized an effusive metal-vapor source using collinear-array of multi-channel. In this note, we describe the theoretical basis of designing the source. Atom density in atomic beam has been estimated using a set of analytical expressions for long-channel operated in transparent mode. Parametric studies on aspect ratio of channel, inter-channel separation, beam width, and vertical distance from the source are carried out. They are useful in providing physical picture and optimizing design parameters.

  1. MicroBooNE Detector Stability MICROBOONE-NOTE-1013-PUB The MicroBooNE

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    MicroBooNE Detector Stability MICROBOONE-NOTE-1013-PUB The MicroBooNE Collaboration June 30, 2016 Abstract The Micro Booster Neutrino Experiment (MicroBooNE) is designed to explore the low- energy excess in the ν e event spectrum reported by the MiniBooNE experiment [1] and to measure ν-Ar cross sections in the 1 GeV energy range. The detector is a liquid argon time projection chamber with wire readout, supplemented with a light detection system based on photo-multiplier tubes (PMTs). The

  2. Attachment 1 - PIC Transcribed Flip Chart Notes Final Meeting Summary Page 12

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    - PIC Transcribed Flip Chart Notes Final Meeting Summary Page 12 Public Involvement Committee September 4, 2013 Strategic Planning: Quarters by month * Q1: Oct. - Dec. * Q2: Jan - March * Q3: April - June * Q4: July - Sept. Page 1 Strategic Planning: 2014 Topics (Interactive activity) * = priority topic for discussion at meeting; �= priority for future discussion | Quarter prioritized for discussion (Q1, Q2, Q3, Q4) * 100-F Proposed Plan | *** Q2 * 100 D-H Proposed Plan * Draft Land

  3. Neutron Physics. A Revision of I. Halpern's notes on E. Fermi's lectures in 1945

    DOE R&D Accomplishments [OSTI]

    Beckerley, J.G.

    1951-10-16

    In the Fall of 1945 a course in Neutron Physics was given by Professor Fermi as part of the program of the Los Alamos University. The course consisted of thirty lectures most of which were given by Fermi. In his absence R.F. Christy and E. Segre gave several lectures. The present revision is based upon class notes prepared by I. Halpern with some assistance by B.T. Feld and issued first as document LADC 255 and later with wider circulation as MDDC 320.

  4. Hanford Advisory Board FY2014 Work Plan - "A" List - Facilitator notes o

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Facilitator notes on midyear status for RAP-lead topics (updated 4/30/14) These are the priority topics that the Board is expected to take action on in FY2014, as agreed to by the TPA and the Board. The timing of these topics drives the need for committee meetings. Their status may change to "topics of interest" if they are delayed or deferred, and if there is agreement to do so among the EIC and Agency Liaisons. Adopted by Consensus, September 6, 2013 Page 1 of 12 Priority Topics -

  5. Notes on the Langevin model for turbulent diffusion of ``marked`` particles

    SciTech Connect (OSTI)

    Rodean, H.C.

    1994-01-26

    Three models for scalar diffusion in turbulent flow (eddy diffusivity, random displacement, and on the Langevin equation) are briefly described. These models random velocity increment based Fokker-Planck equation is introduced as are then examined in more detail in the reverse order. The Fokker-Planck equation is the Eulerian equivalent of the Lagrangian Langevin equation, and the derivation of e outlined. The procedure for obtaining the deterministic and stochastic components of the Langevin equation from Kolmogorov`s 1941 inertial range theory and the Fokker-Planck equation is described. it is noted that a unique form of the Langevin equation can be determined for diffusion in one dimension but not in two or three. The Langevin equation for vertical diffusion in the non-Gaussian convective boundary layer is presented and successively simplified for Gaussian inhomogeneous turbulence and Gaussian homogeneous turbulence in turn. The Langevin equation for Gaussian inhomogeneous turbulence is mathematically transformed into the random displacement model. It is shown how the Fokker-Planck equation for the random displacement model is identical in form to the partial differential equation for the eddy diffusivity model. It is noted that the Langevin model is applicable in two cases in which the other two are not valid: (1) very close in time and distance to the point of scalar release and (2) the non-Gaussian convective boundary layer. The two- and three-dimensional cases are considered in Part III.

  6. Comparison of doubly labeled water with respirometry at low- and high-activity levels

    SciTech Connect (OSTI)

    Westerterp, K.R.; Brouns, F.; Saris, W.H.; ten Hoor, F.

    1988-07-01

    In previous studies the doubly labeled water method for measuring energy expenditure in free-living humans has been validated against respirometry under sedentary conditions. In the present investigation, energy expenditure is measured simultaneously with doubly labeled water and respirometry at low- and high-activity levels. Over 6 days, five subjects were measured doing mainly sedentary activities like desk work; their average daily metabolic rate was 1.40 +/- 0.09 (SD) times sleeping metabolic rate. Four subjects were measured twice over 3.5 days, including 2 days with heavy bicycle ergometer work, resulting in an average daily metabolic rate of 2.61 +/- 0.25 (SD) times sleeping metabolic rate. At the low-activity level, energy expenditures from the doubly labeled water method were on the average 1.4 +/- 3.9% (SD) larger than those from respirometry. At the high-activity level, the doubly labeled water method yielded values that were 1.0 +/- 7.0% (SD) lower than those from respirometry. Results demonstrate the utility of the doubly labeled water method for the determination of energy expenditure in the range of activity levels in daily life.

  7. Microalgae Shows High-Energy Potential as a U.S. Biofuel - News Releases |

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Thru 2009 2010 2011 2012 2013 30-Sep Number of Complaints Filed 50 61 69 73 83 74 Number of Complainants 43 55 60 73 83 74 Repeat Filers 3 4 7 0 0 0 2014 Thru Note: Complaints can be filed alleging multiple bases. 30-Sep The sum of the bases may not equal total complaints filed. Race 14 22 10 24 28 16 Color 12 15 7 15 13 10 Religion 0 3 4 4 1 0 Reprisal 22 33 41 41 48 40 Sex 22 20 25 23 39 30 PDA 0 0 0 2 0 0 National Origin 10 5 7 13 9 6 Equal Pay Act 2 0 4 4 1 2 Complaint Activity Comparative

  8. Leveraging Paraphrase Labels to Extract Synonyms from Twitter

    SciTech Connect (OSTI)

    Antoniak, Maria A.; Bell, Eric B.; Xia, Fei

    2015-05-18

    We present an approach for automatically learning synonyms from a paraphrase corpus of tweets. This work shows improvement on the task of paraphrase detection when we substitute our extracted synonyms into the training set. The synonyms are learned by using chunks from a shallow parse to create candidate synonyms and their context windows, and the synonyms are incorporated into a paraphrase detection system that uses machine translation metrics as features for a classifier. We demonstrate a 2.29% improvement in F1 when we train and test on the paraphrase training set, providing better coverage than previous systems, which shows the potential power of synonyms that are representative of a specific topic.

  9. Indium-111 labeled anti-melanoma monoclonal antibodies

    DOE Patents [OSTI]

    Srivastava, S.C.; Fawwaz, R.A.; Ferrone, S.

    1984-04-30

    A monoclonal antibody to a high molecular weight melanoma-associated antigen was chelated and radiolabeled with indium-111. This material shows high affinity for melanoma and thus can be used in the detection, localization and imaging of melanoma. 1 figure.

  10. Specific Fluorine Labeling of the HyHEL10 Antibody Affects Antigen Binding and Dynamics

    SciTech Connect (OSTI)

    Acchione, Mauro; Lee, Yi-Chien; DeSantis, Morgan E.; Lipschultz, Claudia A.; Wlodawer, Alexander; Li, Mi; Shanmuganathan, Aranganathan; Walter, Richard L.; Smith-Gill, Sandra; Barchi, Jr., Joseph J.

    2012-10-16

    To more fully understand the molecular mechanisms responsible for variations in binding affinity with antibody maturation, we explored the use of site specific fluorine labeling and {sup 19}F nuclear magnetic resonance (NMR). Several single-chain (scFv) antibodies, derived from an affinity-matured series of anti-hen egg white lysozyme (HEL) mouse IgG1, were constructed with either complete or individual replacement of tryptophan residues with 5-fluorotryptophan ({sup 5F}W). An array of biophysical techniques was used to gain insight into the impact of fluorine substitution on the overall protein structure and antigen binding. SPR measurements indicated that {sup 5F}W incorporation lowered binding affinity for the HEL antigen. The degree of analogue impact was residue-dependent, and the greatest decrease in affinity was observed when {sup 5F}W was substituted for residues near the binding interface. In contrast, corresponding crystal structures in complex with HEL were essentially indistinguishable from the unsubstituted antibody. {sup 19}F NMR analysis showed severe overlap of signals in the free fluorinated protein that was resolved upon binding to antigen, suggesting very distinct chemical environments for each {sup 5F}W in the complex. Preliminary relaxation analysis suggested the presence of chemical exchange in the antibody-antigen complex that could not be observed by X-ray crystallography. These data demonstrate that fluorine NMR can be an extremely useful tool for discerning structural changes in scFv antibody-antigen complexes with altered function that may not be discernible by other biophysical techniques.

  11. Meeting notes of the High Flux Isotope Reactor (HFIR) futures group

    SciTech Connect (OSTI)

    Houser, M.M.

    1995-08-01

    This report is a compilation of the notes from the ten meetings. The group charter is: (1) to identify and characterize the range of possibilities and necessities for keeping the HFIR operating for at least the next 15 years; (2) to identify and characterize the range of possibilities for enhancing the scientific and technical utility of the HFIR; (3) to evaluate the benefits or impacts of these possibilities on the various scientific fields that use the HFIR or its products; (4) to evaluate the benefits or impacts on the operation and maintenance of the HFIR facility and the regulatory requirements; (5) to estimate the costs, including operating costs, and the schedules, including downtime, for these various possibilities; and one possible impact of proposed changes may be to stimulate increased pressure for a reduced enrichment fuel for HFIR.

  12. Note on Dirac-Born-Infeld dynamics of the D-brane near NS5-branes

    SciTech Connect (OSTI)

    Chen Bin; Sun Bo

    2005-08-15

    In this note, we investigate the homogeneous radial dynamics of (Dp, NS5) systems without and with one compactified transverse direction, in the framework of Dirac-Born-Infeld effective action. During the homogeneous evolution, the electric field on the D-brane is always conserved and the radial motion could be reduced to a one-dimension dynamical system with an effective potential. When the Dp-brane energy is not high, the brane moves in a restricted region, with the orbits depending on the conserved energy, angular momentum through the form of the effective potential. When the Dp-brane energy is high enough, it can escape to infinity. It turns out that the conserved angular momentum plays an interesting role in the dynamics. Moreover, we discuss the gauge dynamics around the tachyon vacuum and find that the dynamics is very reminiscent of the string fluid in the rolling tachyon case.

  13. EPICS release 3.11 specific documentation -- EPICS release notes for 3.11

    SciTech Connect (OSTI)

    1994-01-19

    EPICS release 3.11 is now ready for user testing. A person who wants to set up a simplified application environment to boot an IOC and create databases using R3.11 should follow the directions in Appendix B, page 27, of the EPICS Source/Release Control Manual, Sept. 20, 1993. The R3.11 EPICS path at ANL/APS is /net/phebos/epics/R3.11 so the command to get the new release is /net/phebos/epics/R3.11/Unix/share/bin/getrel /net/phebos/epics/R3.11. An existing R3.8 short form report can be copied to this new directory and used to create a database. ANL/APS is currently testing an Application Developers Source/Release control system. It is not yet ready for general distribution. Attached are the EPICS R3.11 release notes.

  14. Non-Linear Transmission Line (NLTL) Microwave Source Lecture Notes the United States Particle Accelerator School

    SciTech Connect (OSTI)

    Russell, Steven J.; Carlsten, Bruce E.

    2012-06-26

    We will quickly go through the history of the non-linear transmission lines (NLTLs). We will describe how they work, how they are modeled and how they are designed. Note that the field of high power, NLTL microwave sources is still under development, so this is just a snap shot of their current state. Topics discussed are: (1) Introduction to solitons and the KdV equation; (2) The lumped element non-linear transmission line; (3) Solution of the KdV equation; (4) Non-linear transmission lines at microwave frequencies; (5) Numerical methods for NLTL analysis; (6) Unipolar versus bipolar input; (7) High power NLTL pioneers; (8) Resistive versus reactive load; (9) Non-lineaer dielectrics; and (10) Effect of losses.

  15. A Note on the Fisher Ideal Index Decomposition for Structural Change in Energy Intensity

    SciTech Connect (OSTI)

    Boyd, Gale A.; Roop, Joseph M.

    2004-01-01

    By direct appeal to the theory underlying price index numbers used by the energy decomposition literature, this note proposed the chain weighted Fisher Ideal Index as a formula that solves the ''residual problem;'' i.e., the decomposition is not complete in the sense that the components do not add to the whole. The connection to index number theory also allows us to illustrate that the measures of activity used to define energy intensity need not be additive across the sectors that are involved in the decomposition. We give an empirical example using recent U. S. manufacturing data of the Fisher Ideal Index, compared to the Tornquist Divisia Index, a popular index in the energy literature.

  16. New Lighting Facts Label: Takes the Guess Work Out of Shopping for Light

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Bulbs | Department of Energy New Lighting Facts Label: Takes the Guess Work Out of Shopping for Light Bulbs New Lighting Facts Label: Takes the Guess Work Out of Shopping for Light Bulbs January 25, 2012 - 5:52am Addthis Chris Stewart Senior Communicator at DOE's National Renewable Energy Laboratory If you're like me, it sometimes feels overwhelming standing at the store and staring at a big wall of light bulbs, trying to understand all the lighting choices. With new lighting standards

  17. Energy-efficiency labels and standards: A guidebook for appliances, equipment and lighting

    SciTech Connect (OSTI)

    McMahon, James E.; Wiel, Stephen

    2001-02-16

    Energy-performance improvements in consumer products are an essential element in any government's portfolio of energy-efficiency and climate change mitigation programs. Governments need to develop balanced programs, both voluntary and regulatory, that remove cost-ineffective, energy-wasting products from the marketplace and stimulate the development of cost-effective, energy-efficient technology. Energy-efficiency labels and standards for appliances, equipment, and lighting products deserve to be among the first policy tools considered by a country's energy policy makers. The U.S. Agency for International Development (USAID) and the United Nations Foundation (UNF) recognize the need to support policy makers in their efforts to implement energy-efficiency standards and labeling programs and have developed this guidebook, together with the Collaborative Labeling and Appliance Standards Program (CLASP), as a primary reference. This guidebook was prepared over the course of the past year with significant contribution from the authors and reviewers mentioned previously. Their diligent participation has made this the international guidance tool it was intended to be. The lead authors would also like to thank the following individuals for their support in the development, production, and distribution of the guidebook: Marcy Beck, Elisa Derby, Diana Dhunke, Ted Gartner, and Julie Osborn of Lawrence Berkeley National Laboratory as well as Anthony Ma of Bevilacqua-Knight, Inc. This guidebook is designed as a manual for government officials and others around the world responsible for developing, implementing, enforcing, monitoring, and maintaining labeling and standards-setting programs. It discusses the pros and cons of adopting energy-efficiency labels and standards and describes the data, facilities, and institutional and human resources needed for these programs. It provides guidance on the design, development, implementation, maintenance, and evaluation of the programs

  18. Department of Energy to Take Steps to Remove ENERGY STAR Label on Certain

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    LG Refrigerator-Freezer Models | Department of Energy to Take Steps to Remove ENERGY STAR Label on Certain LG Refrigerator-Freezer Models Department of Energy to Take Steps to Remove ENERGY STAR Label on Certain LG Refrigerator-Freezer Models December 7, 2009 - 12:00am Addthis Washington, DC - The Department of Energy announced today that as part of the expanded enforcement efforts under the ENERGY STAR® program, effective January 2, 2010, certain LG French-door refrigerator-freezers are

  19. Expedited Synthesis of Fluorine-18 Labeled Phenols. A Missing Link in PET Radiochemistry

    SciTech Connect (OSTI)

    Katzenellenbogen, John A.; Zhou, Dong

    2015-03-26

    Fluorine-18 (F-18) is arguably the most valuable radionuclide for positron emission tomographic (PET) imaging. However, while there are many methods for labeling small molecules with F-18 at aliphatic positions and on electron-deficient aromatic rings, there are essentially no reliable and practical methods to label electron-rich aromatic rings such as phenols, with F-18 at high specific activity. This is disappointing because fluorine-labeled phenols are found in many drugs; there are also many interesting plant metabolites and hormones that contain either phenols or other electron-rich aromatic systems such as indoles whose metabolism, transport, and distribution would be interesting to study if they could readily be labeled with F-18. Most approaches to label phenols with F-18 involve the labeling of electron-poor precursor arenes by nucleophilic aromatic substitution, followed by subsequent conversion to phenols by oxidation or other multi-step sequences that are often inefficient and time consuming. Thus, the lack of good methods for labeling phenols and other electron-rich aromatics with F-18 at high specific activity represents a significant methodological gap in F-18 radiochemistry that can be considered a “Missing Link in PET Radiochemistry”. The objective of this research project was to develop and optimize a series of unusual synthetic transformations that will enable phenols (and other electron-rich aromatic systems) to be labeled with F-18 at high specific activity, rapidly, reliably, and conveniently, thereby bridging this gap. Through the studies conducted with support of this project, we have substantially advanced synthetic methodology for the preparation of fluorophenols. Our progress is presented in detail in the sections below, and much has been published or presented publication; other components are being prepared for publication. In essence, we have developed a completely new method to prepare o-fluorophenols from non-aromatic precursors

  20. New Analysis Shows National Potential for Solar Power in Low-Income

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Communities | Department of Energy Analysis Shows National Potential for Solar Power in Low-Income Communities New Analysis Shows National Potential for Solar Power in Low-Income Communities November 18, 2016 - 11:45am Addthis New Analysis Shows National Potential for Solar Power in Low-Income Communities New Analysis Shows National Potential for Solar Power in Low-Income Communities New Analysis Shows National Potential for Solar Power in Low-Income Communities New Analysis Shows National

  1. Using phylogenetic probes for quantification of stable isotope labeling and microbial community analysis

    DOE Patents [OSTI]

    Brodie, Eoin L; DeSantis, Todd Z; Karaoz, Ulas; Andersen, Gary L

    2014-12-09

    Herein is described methods for a high-sensitivity means to measure the incorporation of stable isotope labeled substrates into RNA following stable isotope probing experiments (SIP). RNA is hybridized to a set of probes such as phylogenetic microarrays and isotope incorporation is quantified such as by secondary ion mass spectrometer imaging (NanoSIMS).

  2. Feasibility of an appliance energy testing and labeling program for Sri Lanka

    SciTech Connect (OSTI)

    Biermayer, Peter; Busch, John; Hakim, Sajid; Turiel, Issac; du Pont, Peter; Stone, Chris

    2000-04-01

    A feasibility study evaluated the costs and benefits of establishing a program for testing, labeling and setting minimum efficiency standards for appliances and lighting in Sri Lanka. The feasibility study included: refrigerators, air-conditioners, flourescent lighting (ballasts & CFls), ceiling fans, motors, and televisions.

  3. Kit for the selective labeling of red blood cells in whole blood with [sup 99]Tc

    DOE Patents [OSTI]

    Srivastava, S.C.; Babich, J.W.; Straub, R.; Richards, P.

    1992-05-26

    Disclosed herein are a method and kit for the preparation of [sup 99m]Tc labeled red blood cells using whole blood in a closed sterile system containing stannous tin in a form such that it will enter the red blood cells and be available therein for reduction of technetium. No Drawings

  4. Kit for the selective labeling of red blood cells in whole blood with .sup.9 TC

    DOE Patents [OSTI]

    Srivastava, Suresh C.; Babich, John W.; Straub, Rita; Richards, Powell

    1992-01-01

    Disclosed herein are a method and kit for the preparation of .sup.99m Tc labeled red blood cells using whole blood in a closed sterile system containing stannous tin in a form such that it will enter the red blood cells and be available therein for reduction of technetium.

  5. New method for the selective labeling of erythrocytes in whole blood with Tc-99m

    DOE Patents [OSTI]

    Srivastava, S.C.; Babich, J.W.; Straub, R.; Richards, P.

    1984-01-27

    Method and kit are described for the preparation of /sup 99m/Tc labeled red blood cells using whole blood in a closed sterile system containing stannous tin in a form such that it will enter the red blood cells and be available therein for the reduction of technetium.

  6. D-Zero Central Calorimeter Pressure Vessel and Vacuum Vessel Safety Notes

    SciTech Connect (OSTI)

    Rucinski, R.; Luther, R.; /Fermilab

    1990-10-25

    The relief valve and relief piping capacity was calculated to be 908 sefm air. This exceeds all relieving conditions. The vessel also has a rupture disc with a 2640 scfm air stamped capacity. In order to significantly decrease the amount of time required to fill the cryostats, it is desired to raise the setpoint of the 'operating' relief valve on the argon storage dewar to 20 psig from its existing 16 psig setting. This additional pressure increases the flow to the cryostats and will overwhelm the relief capacity if the temperature of the modules within these vessels is warm enough. Using some conservative assumptions and simple calculations within this note, the maximum average temperature that the modules within each cryostat can be at prior to filling from the storage dewar with liquid argon is at least 290 K. The average temperature of the module mass for any of the three cryostats can be as high as 290 K prior to filling that particular cryostat. This should not be confused with the average temperature of a single type or location which is useful in protecting the modules-not necessarily the vessel itself. A few modules of each type and at different elevations should be used in an average which would account for the different weights of each module. Note that at 290 K, the actual flow of argon through the relief valve and the rupture disk was under the maximum theoretical flows for each relief device. This means that the bulk temperature could actually have been raised to flow argon through the reliefs at their maximum capacity. Therefore, the temperature of 290 K is a conservative value for the calculated flow rate of 12.3 gpm. Safeguards in addition to and used in conjunction with operating procedures shall be implemented in such a way so that the above temperature limitation is not exceeded and such that it is exclusive of the programmable logic controller (PLC). One suggestion is using a toggle switch for each cryostat mounted in the PLC I/O box which

  7. Tidal constituent database. West Coast of the United States and Eastern North pacific ocean. Technical note

    SciTech Connect (OSTI)

    1995-01-01

    This technical note describes a database of tidal elevation boundary condition information generated in support of the `Long-Term Fate of Dredged Material Disposed in Open Water` research of the Dredging Research Program (DRP), being conducted at the U.S. Army Engineer Waterways Experiment Station. The database, described in detail by Hench and others (1994), allows the user to manually generate time series of tidal elevations or to use a program to access the full database to generate time series of both tidal elevations and currents for any location along the West Coast of the United States and Eastern North Pacific Ocean, extending from Seal Cape on Unimak Island, Alaska, in the North to Punta Parada, Peru, in the South. The land boundary includes the Pacific shorelines of Alaska, Canada, mainland United States, Mexico, Guatemala, El Salvador, Nicaragua, Costa Rica, Panama, Columbia, and Northern Peru. Although the capability to generate these time series was developed to provide input to the Long-Term Fate and Stability Model (LTFATE), the generated time series can be used for any application requiring tidal forcing data.

  8. Technical Note: Modeling a complex micro-multileaf collimator using the standard BEAMnrc distribution

    SciTech Connect (OSTI)

    Kairn, T.; Kenny, J.; Crowe, S. B.; Fielding, A. L.; Franich, R. D.; Johnston, P. N.; Knight, R. T.; Langton, C. M.; Schlect, D.; Trapp, J. V.

    2010-04-15

    Purpose: The component modules in the standard BEAMnrc distribution may appear to be insufficient to model micro-multileaf collimators that have trifaceted leaf ends and complex leaf profiles. This note indicates, however, that accurate Monte Carlo simulations of radiotherapy beams defined by a complex collimation device can be completed using BEAMnrc's standard VARMLC component module. Methods: That this simple collimator model can produce spatially and dosimetrically accurate microcollimated fields is illustrated using comparisons with ion chamber and film measurements of the dose deposited by square and irregular fields incident on planar, homogeneous water phantoms. Results: Monte Carlo dose calculations for on-axis and off-axis fields are shown to produce good agreement with experimental values, even on close examination of the penumbrae. Conclusions: The use of a VARMLC model of the micro-multileaf collimator, along with a commissioned model of the associated linear accelerator, is therefore recommended as an alternative to the development or use of in-house or third-party component modules for simulating stereotactic radiotherapy and radiosurgery treatments. Simulation parameters for the VARMLC model are provided which should allow other researchers to adapt and use this model to study clinical stereotactic radiotherapy treatments.

  9. Calculation notes that support accident scenario and consequence of the in-tank fuel fire/deflageration

    SciTech Connect (OSTI)

    Crowe, R.D., Westinghouse Hanford

    1996-09-09

    The purpose of this calculation note is to provide the basis for In-Tank Fuel fire/Deflageration consequence for the Tank Farm Safety Analysis Report (FSAR). Tank Fuel Fire/Deflageration scenario is developed and details and description of the analysis methods are provided.

  10. Calculation notes that support accident scenario and consequence of the in-tank fuel fire/deflagration

    SciTech Connect (OSTI)

    Crowe, R.D.

    1996-09-27

    The purpose of this calculation note is to provide the basis for In-Tank Fuel Fire/Deflageration consequence for the Tank Farm Safety Analysis Report (FSAR). Tank Fuel Fire/Deflageration scenario is developed and details and description of the analysis methods are provided.

  11. Solar and the City: Online Map to Show NYC's Solar Potential...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    and the City: Online Map to Show NYC's Solar Potential Solar and the City: Online Map to Show NYC's Solar Potential October 13, 2010 - 11:32am Addthis Stephen Graff Former Writer & ...

  12. Zip is not in file but shows on EUR | OpenEI Community

    Open Energy Information (Open El) [EERE & EIA]

    Zip is not in file but shows on EUR Home > Groups > Utility Rate Hello, I was looking up electricity providers for the zipcode 90050. While it shows a result using the tool at...

  13. New York Event to Show Bi-Partisan, International Support for...

    Office of Environmental Management (EM)

    New York Event to Show Bi-Partisan, International Support for Geothermal Energy in America New York Event to Show Bi-Partisan, International Support for Geothermal Energy in ...

  14. NETL's 2015 Carbon Storage Atlas Shows Increase in U.S. CO2 Storage...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    NETL's 2015 Carbon Storage Atlas Shows Increase in U.S. CO2 Storage Potential NETL's 2015 Carbon Storage Atlas Shows Increase in U.S. CO2 Storage Potential September 28, 2015 - ...

  15. Map showing surficial geology of the Lathrop Wells Quadrangle, Nye County, Nevada

    SciTech Connect (OSTI)

    Swadley, W.C.

    1983-12-31

    This map shows the geology of the Lathrop Wells quadrangle located just south of the Nevada Test Site. 6 refs.

  16. ISSUANCE 2016-06-10: Energy Conservation Program: Certification, Compliance, Labeling, and Enforcement for Electric Motors and Small Electric Motors, Notice of Proposed Rulemaking

    Office of Energy Efficiency and Renewable Energy (EERE)

    Energy Conservation Program: Certification, Compliance, Labeling, and Enforcement for Electric Motors and Small Electric Motors, Notice of Proposed Rulemaking

  17. Synthesis and preliminary biological evaluations of fluorescent or 149Promethium labeled Trastuzumab-polyethylenimine

    SciTech Connect (OSTI)

    Fitzsimmons, Jonathan; Nayak, Tapan; Cutler, Cathy; Atcher, Robert

    2015-12-30

    Radioimmunotherapy utilize a targeting antibody coupled to a therapeutic isotope to target and treat a tumor or disease. In this study we examine the synthesis and cell binding of a polymer scaffold containing a radiotherapeutic isotope and a targeting antibody. Methods: The multistep synthesis of a fluorescent or 149Promethium-labeled Trastuzumab-polyethyleneimine (PEI), Trastuzumab, or PEI is described. In vitro uptake, internalization and/or the binding affinity to the Her2/neu expressing human breast adenocarcinoma SKBr3 cells was investigated with the labeled compounds. Fluorescent-labeled Trastuzumab-PEI was internalized more into cells at 2 and 18 h than fluorescent-labeled Trastuzumab or PEI. The fluorescent-labeled Trastuzumab was concentrated on the cell surface at 2 and 18 h and the labeled PEI had minimal uptake. DOTA-PEI was prepared and contained an average of 16 chelates per PEI; the compound was radio-labeled with 149Promethium and conjugated to Trastuzumab. The purified 149Pm-DOTA-PEI-Trastuzumab had a radiochemical purity of 96.7% and a specific activity of 0.118 TBq/g. The compound demonstrated a dissociation constant for the Her2/neu receptor of 20.30 ± 6.91 nM. In conclusion, the results indicate the DOTA-PEI-Trastuzumab compound has potential as a targeted therapeutic carrier, and future in vivo studies should be performed.

  18. High-resolution x-ray diffraction microscopy of specifically labeled yeast cells

    SciTech Connect (OSTI)

    Nelson, Johanna; Huang, Xiaojing; Steinbrener, Jan; Shapiro, David; Kirz, Janos; Marchesini, Stephano; Neiman, Aaron M.; Turner, Joshua J.; Jacobsen, Chris

    2010-04-20

    X-ray diffraction microscopy complements other x-ray microscopy methods by being free of lens-imposed radiation dose and resolution limits, and it allows for high-resolution imaging of biological specimens too thick to be viewed by electron microscopy. We report here the highest resolution (11-13 nm) x-ray diffraction micrograph of biological specimens, and a demonstration of molecular-specific gold labeling at different depths within cells via through-focus propagation of the reconstructed wavefield. The lectin concanavalin A conjugated to colloidal gold particles was used to label the ?-mannan sugar in the cell wall of the yeast Saccharomyces cerevisiae. Cells were plunge-frozen in liquid ethane and freeze-dried, after which they were imaged whole using x-ray diffraction microscopy at 750 eV photon energy.

  19. High-resolution x-ray diffraction microscopy of specifically labeled yeast cells

    DOE PAGES-Beta [OSTI]

    Nelson, Johanna; Huang, Xiaojing; Steinbrener, Jan; Shapiro, David; Kirz, Janos; Marchesini, Stephano; Neiman, Aaron M.; Turner, Joshua J.; Jacobsen, Chris

    2010-04-20

    X-ray diffraction microscopy complements other x-ray microscopy methods by being free of lens-imposed radiation dose and resolution limits, and it allows for high-resolution imaging of biological specimens too thick to be viewed by electron microscopy. We report here the highest resolution (11-13 nm) x-ray diffraction micrograph of biological specimens, and a demonstration of molecular-specific gold labeling at different depths within cells via through-focus propagation of the reconstructed wavefield. The lectin concanavalin A conjugated to colloidal gold particles was used to label the α-mannan sugar in the cell wall of the yeast Saccharomyces cerevisiae. Cells were plunge-frozen in liquid ethane andmore » freeze-dried, after which they were imaged whole using x-ray diffraction microscopy at 750 eV photon energy.« less

  20. Regional cooperation in energy efficiency standard-setting and labeling in North America

    SciTech Connect (OSTI)

    Wiel, Stephen; Van Wie McGrory, Laura

    2003-08-04

    The North American Energy Working Group (NAEWG) was established in 2001 by the governments of Canada, Mexico, and the United States. The goals of NAEWG are to foster communication and cooperation on energy-related matters of common interest, and to enhance North American energy trade and interconnections consistent with the goal of sustainable development, for the benefit of all three countries. At its outset, NAEWG established teams to address different aspects of the energy sector. One, the Energy Efficiency Expert Group, undertook activity in three areas: (1) analyzing commonalities and differences in the test procedures of Canada, Mexico, and the United States, and identifying specific products for which the three countries might consider harmonization; (2) exploring possibilities for increased mutual recognition of laboratory test results; and (3) looking at possibilities for enhanced cooperation in the Energy Star voluntary endorsement labeling program. To support NAEWG's Expert Group on Energy Efficiency (NAEWG-EE), USDOE commissioned Lawrence Berkeley National Laboratory, representing the Collaborative Labeling and Appliance Standards Program (CLASP), to prepare a resource document comparing current standards, labels, and test procedure regulations in Canada, Mexico, and the United States. The resulting document identified 46 energy-using products for which at least one of the three countries has energy efficiency regulations. Three products--refrigerators/freezers, room air conditioners, and integral horsepower three-phase electric motors--have identical minimum energy performance standards (MEPS) and test procedures in the three countries. Ten other products have different MEPS and test procedures, but have the near-term potential for harmonization. NAEWG-EE is currently working to identify mechanisms for mutual recognition of test results. With consultative support from the United States and Canada through NAEWG-EE, Mexico is exploring possibilities for

  1. Alexa Fluor-labeled Fluorescent Cellulose Nanocrystals for Bioimaging Solid Cellulose in Spatially Structured Microenvironments

    SciTech Connect (OSTI)

    Grate, Jay W.; Mo, Kai-For; Shin, Yongsoon; Vasdekis, Andreas; Warner, Marvin G.; Kelly, Ryan T.; Orr, Galya; Hu, Dehong; Dehoff, Karl J.; Brockman, Fred J.; Wilkins, Michael J.

    2015-03-18

    Cellulose nanocrystal materials have been labeled with modern Alexa Fluor dyes in a process that first links the dye to a cyanuric chloride molecule. Subsequent reaction with cellulose nanocrystals provides dyed solid microcrystalline cellulose material that can be used for bioimaging and suitable for deposition in films and spatially structured microenvironments. It is demonstrated with single molecular fluorescence microscopy that these films are subject to hydrolysis by cellulose enzymes.

  2. Energy expenditure and socioeconomic status in Guatemala as measured by the doubly labelled water method

    SciTech Connect (OSTI)

    Stein, T.P.; Johnston, F.E.; Greiner, L.

    1988-02-01

    The energy expenditure of lower (group 1) and upper socioeconomic group females (group 2) from a marginal community in Guatemala City was determined by using the doubly labelled water method. Energy expenditure values were 1925 +/- 66 (mean, SEM) kcal/d (group 1) and 2253 +/- 145 kcal/d group 2 (p less than 0.03). About half of this difference can be attributed to size.

  3. Method for preparing radionuclide-labeled chelating agent-ligand complexes

    DOE Patents [OSTI]

    Meares, Claude F.; Li, Min; DeNardo, Sally J.

    1999-01-01

    Radionuclide-labeled chelating agent-ligand complexes that are useful in medical diagnosis or therapy are prepared by reacting a radionuclide, such as .sup.90 Y or .sup.111 In, with a polyfunctional chelating agent to form a radionuclide chelate that is electrically neutral; purifying the chelate by anion exchange chromatography; and reacting the purified chelate with a targeting molecule, such as a monoclonal antibody, to form the complex.

  4. Saint-Gobain Shows the Way on Effectively Preparing for Energy Savings

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Assessments | Department of Energy Saint-Gobain Shows the Way on Effectively Preparing for Energy Savings Assessments Saint-Gobain Shows the Way on Effectively Preparing for Energy Savings Assessments This case study examines how Saint-Gobain used its history in energy efficiency and experiences with DOE initiatives to develop a generic approach for any plant to effectively prepare for an energy assessment. Saint-Gobain Shows the Way on Effectively Preparing for Energy Savings Assessments

  5. Canada, Mexico and the United States Show Progress on North American Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Collaboration | Department of Energy Canada, Mexico and the United States Show Progress on North American Energy Collaboration Canada, Mexico and the United States Show Progress on North American Energy Collaboration June 3, 2016 - 3:48pm Addthis Canada, Mexico and the United States Show Progress on North American Energy Collaboration News Media Contact (202) 586-4940 DOENews@hq.doe.gov SAN FRANCISCO, Calif. - In support of the objectives of the 7th Clean Energy Ministerial (CEM) and

  6. Fact #910: February 1, 2016 Study Shows Average Cost of Electric Vehicle

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Charger Installations - Dataset | Department of Energy 0: February 1, 2016 Study Shows Average Cost of Electric Vehicle Charger Installations - Dataset Fact #910: February 1, 2016 Study Shows Average Cost of Electric Vehicle Charger Installations - Dataset Excel file and dataset for Study Shows Average Cost of Electric Vehicle Charger Installations fotw#910_web.xlsx (16.26 KB) More Documents & Publications Fact #909: January 25, 2016 Workplace Charging Accounts for About a Third of All

  7. A crystallographer keen on showing off the revealing properties of neutrons

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Revealing properties of neutrons A crystallographer keen on showing off the revealing properties of neutrons Olivier Gourdon shows visiting researchers some of the latest tricks that can be performed using this 100-year old multidisciplinary science. February 27, 2014 Olivier Gourdon Olivier Gourdon "With neutron diffraction, we can learn much more than where are the atoms." At Los Alamos's Lujan Neutron Scattering Center, crystallographer Olivier Gourdon shows visiting researchers

  8. Labeling of Cp-105,191. Unusual findings on triphenyltin hydride reduction of an aryl iodide

    SciTech Connect (OSTI)

    McCarthy, P.A.; Diaz, C.L.; Zawistoski, M.P.

    1995-12-01

    CP-105,191 (1) is a potent, selective and systemically-available inhibitor of acyl-coenzyme A:cholesterol acyl transferase. We needed to make tritium-labeled 1 in order to facilitate the preclinical evaluation of the pharmacokinetics and systemic anti-atherosclerosis effects of 1. Desiring to introduce the tritium as the last step in the synthesis, we opted for introduction of the tritium into the quinoline nucleus via reduction of an 8-iodo species (8, synthesis to be described). To our surprise, treatment of 8 with distilled triphenyltin deuteride and catalytic AIBN in diglyme at reflux for 2 hours gave 67-72% yield of 1 with no deuterium incorporation. Consideration of these results and others to be presented suggests that the solvent is participating in radical chain propagation and that this reaction was unsuitable for tritium labeling. After these results, we found that reduction of 8 with atmospheric pressure of deuterium catalyzed by palladium on carbon in ethanol and triethylamine gave 75-95% yield of 1 with complete deuterium incorporation at C8 of the quinoline ring. The same reaction using 4 Ci of tritium gas gave 1.8 Ci of tritium-labeled 1 with specific activity of 20 Ci/mmole and 97% radiochemical purity.

  9. Apparatus for reading two-dimensional electrophoretograms containing. beta. -ray-emitting labeled compounds

    DOE Patents [OSTI]

    Anderson, H.L.; Kinnison, W.W.; Lillberg, J.W.

    1985-04-30

    An apparatus and method for electronically reading planar two-dimensional ..beta..-ray emitter-labeled gel electrophoretograms. A single, flat rectangular multiwire proportional chamber is placed in close proximity to the gel and the assembly placed in an intense uniform magnetic field disposed in a perpendicular manner to the rectangular face of the proportional chamber. Beta rays emitted in the direction of the proportional chamber are caused to execute helical motions which substantially preserve knowledge the coordinates of their origin in the gel. Perpendicularly oriented, parallel wire, parallel plane cathodes electronically sense the location of the ..beta..-rays from ionization generated thereby in a detection gas coupled with an electron avalanche effect resulting from the action of a parallel wire anode located therebetween. A scintillator permits the present apparatus to be rendered insensitive when signals are generated from cosmic rays incident on the proportional chamber. Resolution for concentrations of radioactive compounds in the gel exceeds 700-..mu..m. The apparatus and method of the present invention represent a significant improvement over conventional autoradiographic techniques in dynamic range, linearity and sensitivity of data collection. A concentration and position map for gel electrophoretograms having significant concentrations of labeled compounds and/or highly radioactive labeling nuclides can generally be obtained in less than one hour.

  10. Apparatus and method for reading two-dimensional electrophoretograms containing .beta.-ray-emitting labeled compounds

    DOE Patents [OSTI]

    Anderson, Herbert L.; Kinnison, W. Wayne; Lillberg, John W.

    1987-01-01

    Apparatus and method for electronically reading planar two dimensional .beta.-ray emitter-labeled gel electrophoretograms. A single, flat rectangular multiwire proportional chamber is placed in close proximity to the gel and the assembly placed in an intense uniform magnetic field disposed in a perpendicular manner to the rectangular face of the proportional chamber. Beta rays emitted in the direction of the proportional chamber are caused to execute helical motions which substantially preserve knowledge of the coordinates of their origin in the gel. Perpendicularly oriented, parallel wire, parallel plane cathodes electronically sense the location of the .beta.-rays from ionization generated thereby in a detection gas coupled with an electron avalanche effect resulting from the action of a parallel wire anode located therebetween. A scintillator permits the present apparatus to be rendered insensitive when signals are generated from cosmic rays incident on the proportional chamber. Resolution for concentrations of radioactive compounds in the gel exceeds 700 .mu.m. The apparatus and method of the present invention represent a significant improvement over conventional autoradiographic techniques in dynamic range, linearity and sensitivity of data collection. A concentration and position map for gel electrophoretograms having significant concentrations of labeled compounds and/or highly radioactive labeling nuclides can generally be obtained in less than one hour.

  11. 2006 Status Report Savings Estimates for the ENERGY STAR(R)Voluntary Labeling Program

    SciTech Connect (OSTI)

    Webber, Carrie A.; Brown, Richard E.; Sanchez, Marla; Homan,Gregory K.

    2006-03-07

    ENERGY STAR(R) is a voluntary labeling program designed toidentify and promote energy-efficient products, buildings and practices.Operated jointly by the Environmental Protection Agency (EPA) and theU.S. Department of Energy (DOE), ENERGY STAR labels exist for more thanthirty products, spanning office equipment, residential heating andcooling equipment, commercial and residential lighting, home electronics,and major appliances. This report presents savings estimates for a subsetof ENERGY STAR labeled products. We present estimates of the energy,dollar and carbon savings achieved by the program in the year 2005, whatwe expect in 2006, and provide savings forecasts for two marketpenetration scenarios for the periods 2006 to 2015 and 2006 to 2025. Thetarget market penetration forecast represents our best estimate of futureENERGY STAR savings. It is based on realistic market penetration goalsfor each of the products. We also provide a forecast under the assumptionof 100 percent market penetration; that is, we assume that all purchasersbuy ENERGY STAR-compliant products instead of standard efficiencyproducts throughout the analysis period.

  12. Probing Xylan-Specific Raman Bands for Label-Free Imaging Xylan in Plant Cell Wall

    SciTech Connect (OSTI)

    Zeng, Yining; Yarbrough, John M.; Mittal, Ashutosh; Tucker, Melvin P.; Vinzant, Todd; Himmel, Michael E.

    2015-06-15

    Xylan constitutes a significant portion of biomass (e.g. 22% in corn stover used in this study). Xylan is also an important source of carbohydrates, besides cellulose, for renewable and sustainable energy applications. Currently used method for the localization of xylan in biomass is to use fluorescence confocal microscope to image the fluorescent dye labeled monoclonal antibody that specifically binds to xylan. With the rapid adoption of the Raman-based label-free chemical imaging techniques in biology, identifying Raman bands that are unique to xylan would be critical for the implementation of the above label-free techniques for in situ xylan imaging. Unlike lignin and cellulose that have long be assigned fingerprint Raman bands, specific Raman bands for xylan remain unclear. The major challenge is the cellulose in plant cell wall, which has chemical units highly similar to that of xylan. Here we report using xylanase to specifically remove xylan from feedstock. Under various degree of xylan removal, with minimum impact to other major cell wall components, i.e. lignin and cellulose, we have identified Raman bands that could be further tested for chemical imaging of xylan in biomass in situ.

  13. Top students show off brain power at Kansas City Science Bowl...

    National Nuclear Security Administration (NNSA)

    During the many rounds of competition, students showed a remarkable understanding of chemistry, geology, physics, biology, electronics, and more as they used brainpower to compete ...

  14. Fact #910: February 1, 2016 Study Shows Average Cost of Electric...

    Energy.gov (indexed) [DOE]

    site and other factors such as permit and inspection fees. Installation Costs of Electric Vehicle Charging Stations by Type, 2011-2013 (INL Study) Graph showing installation costs ...

  15. Energy Secretary Moniz at the 2016 Washington Auto Show | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Energy Secretary Moniz at the 2016 Washington Auto Show Energy Secretary Moniz at the 2016 Washington Auto Show Addthis Topic Loans Alternative Fuel Vehicles Hydrogen Hydrogen & Fuel Cells Learn about some of the amazing Energy Department-supported vehicle technologies that are lowering carbon pollution and driving America's clean energy economy forward.

  16. Secretary Chu Tours the 2013 Washington Auto Show | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Tours the 2013 Washington Auto Show Secretary Chu Tours the 2013 Washington Auto Show January 31, 2013 - 5:04pm Addthis 1 of 10 While at the Washington Auto Show, Energy Secretary Steven Chu visited Nissan to see the 2013 Leaf. | Photo courtesy of Sarah Gerrity, Energy Department. Date taken: 2013-01-31 13:50 2 of 10 The new Nissan Leaf is being built at the company's Smyrna, Tennessee, Vehicle Assembly Plant -- helping to cut the price of its electric vehicle. | Photo courtesy of Sarah Gerrity,

  17. NREL Report Shows Big Potential for the Future of Shared Solar | Department

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    of Energy NREL Report Shows Big Potential for the Future of Shared Solar NREL Report Shows Big Potential for the Future of Shared Solar April 28, 2015 - 1:54pm Addthis NREL Report Shows Big Potential for the Future of Shared Solar David Feldman David Feldman Energy Analyst, Department of Energy's National Renewable Energy Laboratory In 2014, the United States brought online as much solar energy every three weeks as it did in all of 2008. Demand for solar electricity is driving this growth in

  18. X-ray Imaging Shows Feather Patterns of First Birds | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    X-ray Imaging Shows Feather Patterns of First Birds X-ray Imaging Shows Feather Patterns of First Birds June 30, 2011 - 2:56pm Addthis A collage of images. Top, optical images of: blue jay feather, squid, and fossil fish with feather. Bottom: x-ray images showing the distribution of copper (red) in the same organisms. | Photo Courtesy of Gregory Stewart, SLAC National Accelerator Laboratory A collage of images. Top, optical images of: blue jay feather, squid, and fossil fish with feather.

  19. Energy Department Reports Show Strong Growth of U.S. Wind Power |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Reports Show Strong Growth of U.S. Wind Power Energy Department Reports Show Strong Growth of U.S. Wind Power August 17, 2016 - 11:44am Addthis Photo by Patsy McEnroe Photography. Photo by Patsy McEnroe Photography. Continued Low Wind Energy Prices Highlighted in Annual State-of-the-Industry Market Reports Annual reports analyzing the wind energy industry released today by the Energy Department show continued rapid growth in wind power installations in 2015,

  20. Sample Memorandum to Reactivate a Directive Placed on Hold (NOTE: Per Office of Executive Secretariat procedures, please use

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Sample Memorandum to Reactivate a Directive Placed on Hold (NOTE: Per Office of Executive Secretariat procedures, please use Calibri, 12 point font for this memorandum.) (Effective April 2014) MEMORANDUM FOR: XXXXXXXXXXXXXXXX ASSOCIATE ADMINISTRATOR FOR MANAGEMENT AND BUDGET THROUGH: INGRID KOLB DIRECTOR, OFFICE OF MANAGEMENT FROM: XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX SUBJECT: Request to Reactivate Directive Currently on Hold PURPOSE: The purpose of this memorandum is to request the Directives

  1. Some notes on the calculation of energy-angle correlated distributions with TNG and their representation in File 6 formats

    SciTech Connect (OSTI)

    Larson, D.C.; Fu, C.Y.; Hetrick, D.M.

    1987-01-01

    The model code TNG has been extensively used in evaluation work of structural materials for ENDF/B-VI performed at Oak Ridge National Laboratory. A new aspect of ENDF/B-VI is the use of File 6 formats for energy-angle correlated data. Such data are generally calculated, anchored by experimental data. In this informal note we outline how the TNG results are calculated and entered in the File 6 formats. 4 refs.

  2. ORISE report shows number of health physics Ph.D.s declined in...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    ORISE report shows number of health physics Ph.D.s declined in 2009 FOR IMMEDIATE RELEASE June 15, 2010 FY10-37 OAK RIDGE, Tenn.-Health physics undergraduate degrees increased...

  3. Buckle up for the #LabsRoadShow | Department of Energy

    Energy Savers

    With the Fourth of July right around the corner, what's more American than taking a road trip? Join us as we embark on the National Labs Road Show, a virtual journey to meet the ...

  4. B&W Y-12 responds to NNSA's show cause letter | Y-12 National...

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    responds to ... B&W Y-12 responds to NNSA's show cause letter Posted: September 12, 2012 - 3:29pm On September 10, B&W Y-12 provided its response to the National Nuclear Security ...

  5. David Friedman: On the Future of Transportation and the LA Auto Show

    Energy.gov [DOE]

    David Friedman, Principal Deputy Assistant Secretary in the Energy Department's Office of Energy Efficiency & Renewable Energy (EERE), visited the L.A. Auto Show in November 2015. In this video...

  6. David Friedman: On the Future of Transportation and the L.A. Auto Show

    Energy.gov [DOE]

    David Friedman, Principal Deputy Assistant Secretary, Office of Energy Efficiency & Renewable Energy, visited the L.A. Auto Show in November 2015. He shared his thoughts about transportation's future in this video.

  7. The Consumer Electronics Show round-up | OpenEI Community

    Open Energy Information (Open El) [EERE & EIA]

    The highlights of this year's show were OLED TVs, ultra-thin laptops, tablets, and smartphones. However, a few smart grid-related technologies were making an impression. There...

  8. Thursday: Secretary Moniz to Make Remarks at the Washington Auto Show

    Energy.gov [DOE]

    Tomorrow, Energy Secretary Ernest Moniz will attend the Washington Auto Show and make an important announcement about supporting the U.S. clean energy economy and the 21st century automotive industry.

  9. "Show Preview" button is not working; gives error | OpenEI Community

    Open Energy Information (Open El) [EERE & EIA]

    "Show Preview" button is not working; gives error Home > Groups > Utility Rate Submitted by Ewilson on 3 January, 2013 - 09:52 1 answer Points: 0 Eric, thanks for reporting this. I...

  10. Crystal structure of the N-terminal region of human Ash2L shows...

    Office of Scientific and Technical Information (OSTI)

    of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding Citation Details In-Document Search Title: Crystal structure of the N-terminal ...

  11. How Would IBM's Quiz-Show Computer, Watson, Do as a Competitor...

    Office of Science (SC) [DOE]

    How Would IBM's Quiz-Show Computer, Watson, Do as a Competitor in the National Science Bowl? News News Home Featured Articles 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 ...

  12. NREL Shows Heavy Duty Hybrid Trucks Deliver on Fuel Economy - News Releases

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    | NREL NREL Shows Heavy Duty Hybrid Trucks Deliver on Fuel Economy September 11, 2012 A performance evaluation of Class 8 hybrid electric tractor trailers compared with similar conventional vehicles by the U.S. Department of Energy's (DOE's) National Renewable Energy Laboratory (NREL) shows significant improvements in fuel economy. "During our 13-month study, the hybrid tractors demonstrated 13.7 percent higher fuel economy than the conventional tractors, resulting in a 12 percent

  13. NREL Study Shows 20 Percent Wind is Possible by 2024 - News Releases | NREL

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    NREL Study Shows 20 Percent Wind is Possible by 2024 Analysis Shows Transmission Upgrades, Offshore Wind, and Operational Changes Needed to Incorporate 20 to 30 Percent Wind January 20, 2010 Today, the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) released the Eastern Wind Integration and Transmission Study (EWITS). This unprecedented two-and-a-half year technical study of future high-penetration wind scenarios was designed to analyze the economic, operational,

  14. NREL Study: Hybrid Delivery Vans Show Nearly 20 Percent Higher Fuel Economy

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    - News Releases | NREL Study: Hybrid Delivery Vans Show Nearly 20 Percent Higher Fuel Economy September 28, 2012 The U.S. Department of Energy's (DOE)'s National Renewable Energy Laboratory (NREL) recently completed a performance evaluation report that showed significant fuel economy benefits of hybrid electric delivery vans compared to similar conventional vans. "During the on-road portion of our study, the hybrid vans demonstrated a 13 to 20 percent higher fuel economy than the

  15. Fact #910: February 1, 2016 Study Shows Average Cost of Electric Vehicle

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Charger Installations | Department of Energy 0: February 1, 2016 Study Shows Average Cost of Electric Vehicle Charger Installations Fact #910: February 1, 2016 Study Shows Average Cost of Electric Vehicle Charger Installations SUBSCRIBE to the Fact of the Week The EV Project and the ChargePoint America project were conducted for the Department of Energy by Idaho National Laboratory (INL). From 2011-2013 the project installed nearly 17,000 alternating current (AC) Level 2 charging stations

  16. Life-Cycle Analysis Shows Potential for Almost 70% Greenhouse Gas Emissions

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Reductions of Renewable Diesel from Algae Fractionation Compared to Conventional Diesel | Department of Energy Life-Cycle Analysis Shows Potential for Almost 70% Greenhouse Gas Emissions Reductions of Renewable Diesel from Algae Fractionation Compared to Conventional Diesel Life-Cycle Analysis Shows Potential for Almost 70% Greenhouse Gas Emissions Reductions of Renewable Diesel from Algae Fractionation Compared to Conventional Diesel October 21, 2016 - 12:05pm Addthis A new analysis from

  17. 2014 Data Book Shows Increased Use of Renewable Electricity - News Releases

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    | NREL 2014 Data Book Shows Increased Use of Renewable Electricity December 9, 2015 The 2014 Renewable Energy Data Book shows that U.S. renewable electricity grew to 15.5 percent of total installed capacity and 13.5 percent of total electricity generation. Published annually by the National Renewable Energy Laboratory (NREL) on behalf of the Energy Department's Office of Energy Efficiency and Renewable Energy, the Data Book illustrates United States and global energy statistics, including

  18. New Study Shows Solar Manufacturing Costs Not Driven Primarily by Labor |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Shows Solar Manufacturing Costs Not Driven Primarily by Labor New Study Shows Solar Manufacturing Costs Not Driven Primarily by Labor September 5, 2013 - 12:00pm Addthis Production scale, not lower labor costs, drives China's current advantage in manufacturing photovoltaic (PV) solar energy systems, according to a new report released today by the Energy Department's National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT). Although

  19. New York Event to Show Bi-Partisan, International Support for Geothermal

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Energy in America | Department of Energy York Event to Show Bi-Partisan, International Support for Geothermal Energy in America New York Event to Show Bi-Partisan, International Support for Geothermal Energy in America June 29, 2008 - 4:15pm Addthis NEW YORK, -- Demonstrating the widespread support for renewable, geothermal energy, the President of Iceland as well as officials of the current Bush and former Clinton Administrations are scheduled to speak at a workshop in New York City, July

  20. Study Shows Active Power Controls from Wind May Increase Revenues and

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Improve System Reliability | Department of Energy Shows Active Power Controls from Wind May Increase Revenues and Improve System Reliability Study Shows Active Power Controls from Wind May Increase Revenues and Improve System Reliability January 6, 2014 - 10:00am Addthis This is an excerpt from the Fourth Quarter 2013 edition of the Wind Program R&D Newsletter. The U.S. Department of Energy's Wind Program and the National Renewable Energy Laboratory (NREL) recently published a study

  1. Boron-Nitride Nanotubes Show Potential in Cancer Treatment | Jefferson Lab

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Boron-Nitride Nanotubes Show Potential in Cancer Treatment Boron-Nitride Nanotubes Show Potential in Cancer Treatment NEWPORT NEWS, VA, April 26 - A new study has shown that adding boron-nitride nanotubes to the surface of cancer cells can double the effectiveness of Irreversible Electroporation, a minimally invasive treatment for soft tissue tumors in the liver, lung, prostate, head and neck, kidney and pancreas. Although this research is in the very early stages, it could one day lead to

  2. U.S. diesel fuel price shows no movement from a week ago

    U.S. Energy Information Administration (EIA) (indexed site)

    diesel fuel price shows no movement from a week ago The U.S. average retail price for on-highway diesel fuel showed no movement from a week ago. The average price remained flat at $3.81 a gallon on Monday, based on the weekly price survey by the U.S. Energy Information Administration. Diesel prices were highest in the West Coast region at 4.03 a gallon, up 4-tenths of a penny from a week ago. Prices were lowest in the Gulf Coast region at 3.72 a gallon, down half a penny.

  3. Better Buildings Challenge Webinar: Show Me the Money!: How to Find

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Financing, Access Incentives, and Get Projects Done | Department of Energy Better Buildings Challenge Webinar: Show Me the Money!: How to Find Financing, Access Incentives, and Get Projects Done Better Buildings Challenge Webinar: Show Me the Money!: How to Find Financing, Access Incentives, and Get Projects Done December 6, 2016 1:00PM to 2:00PM MST The Better Buildings Challenge is hosting a webinar to demo the Efficiency Financing Navigator, a new tool to help find the right financing,

  4. 4 Charts That Show Renewable Energy is on the Rise in America | Department

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    of Energy Charts That Show Renewable Energy is on the Rise in America 4 Charts That Show Renewable Energy is on the Rise in America November 14, 2016 - 3:30pm Addthis In 2015 alone, installed wind capacity increased by more than 12% (8,100 megawatts), accounting for more than half of all new renewable capacity additions in the United States. | <em>Photo credit: Warren Gretz/NREL</em> In 2015 alone, installed wind capacity increased by more than 12% (8,100 megawatts), accounting

  5. New Report Shows Trend Toward Larger Offshore Wind Systems, with 11

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Advanced Stage Projects Proposed in U.S. Waters | Department of Energy Trend Toward Larger Offshore Wind Systems, with 11 Advanced Stage Projects Proposed in U.S. Waters New Report Shows Trend Toward Larger Offshore Wind Systems, with 11 Advanced Stage Projects Proposed in U.S. Waters October 23, 2013 - 10:52am Addthis The Energy Department today released a new report showing progress for the U.S. offshore wind energy market in 2012, including the completion of two commercial lease auctions

  6. Sour Gas Streams Safe for Carbon Sequestration, DOE-Sponsored Study Shows |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Sour Gas Streams Safe for Carbon Sequestration, DOE-Sponsored Study Shows Sour Gas Streams Safe for Carbon Sequestration, DOE-Sponsored Study Shows September 23, 2010 - 1:00pm Addthis Washington, D.C. -- Gas streams containing high levels of both carbon dioxide (CO2) and hydrogen sulfide (H2S) can be safely used for carbon capture and storage (CCS), according to results from a field test completed by the Plains CO2 Reduction (PCOR) Partnership. The test by PCOR--one of

  7. ORISE report shows number of health physics Ph.D.s declined in 2009

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    ORISE report shows number of health physics Ph.D.s declined in 2009 FOR IMMEDIATE RELEASE June 15, 2010 FY10-37 OAK RIDGE, Tenn.-Health physics undergraduate degrees increased slightly in 2009 continuing a six-year trend, but doctorate degrees reported a 40-year low, says a report recently released by the Oak Ridge Institute for Science and Education. The report also showed the number of M.S. degrees was 21 percent less than in 2008. The ORISE report, Health Physics Enrollments and Degrees

  8. New Carbon Storage Atlas Shows Hundreds of Years of CO2 Storage Potential |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Carbon Storage Atlas Shows Hundreds of Years of CO2 Storage Potential New Carbon Storage Atlas Shows Hundreds of Years of CO2 Storage Potential December 21, 2012 - 9:58am Addthis Atlas IV was created by the National Energy Technology Laboratory (NETL), and includes input from the more than 400 organizations in 43 states and four Canadian provinces that make up the Department’s seven Regional Carbon Sequestration Partnerships (as shown above). <a

  9. Circleville, Ohio Solar Plant Shows Value of Clean Energy Tax Credits |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Circleville, Ohio Solar Plant Shows Value of Clean Energy Tax Credits Circleville, Ohio Solar Plant Shows Value of Clean Energy Tax Credits May 22, 2012 - 5:03pm Addthis NEWS MEDIA CONTACT (202) 586-4940 WASHINGTON -- As part of the Obama Administration's all-out, all-of-the-above approach to American energy, U.S. Energy Secretary Steven Chu today recognized the grand opening of DuPont's expanded manufacturing plant in Circleville, Ohio and called on Congress to extend

  10. Cummins Case Study Shows a 12.6% Improvement in Energy Performance with SEP

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    | Department of Energy Technical Assistance » Superior Energy Performance » Cummins Case Study Shows a 12.6% Improvement in Energy Performance with SEP Cummins Case Study Shows a 12.6% Improvement in Energy Performance with SEP August 6, 2015 - 11:38am Addthis A recently published case study examines the successes of Cummins Inc., a global engine manufacturer that implemented an energy management system (EnMS) that meets the requirements of ISO 50001 and Superior Energy Performance®

  11. Studies Show No Evidence of Impacts from Wind on Residential Property

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Values | Department of Energy Studies Show No Evidence of Impacts from Wind on Residential Property Values Studies Show No Evidence of Impacts from Wind on Residential Property Values January 6, 2014 - 10:00am Addthis Multi-story farm buildings, grain silos, and trees look small compared to the two multimegawatt wind turbines. This is an excerpt from the Fourth Quarter 2013 edition of the Wind Program R&D Newsletter. The U.S. Department of Energy's Lawrence Berkeley National Laboratory

  12. F-18 Labeled Diabody-Luciferase Fusion Proteins for Optical-ImmunoPET

    SciTech Connect (OSTI)

    Wu, Anna M

    2013-01-18

    The goal of the proposed work is to develop novel dual-labeled molecular imaging probes for multimodality imaging. Based on small, engineered antibodies called â??diabodiesâ?, these probes will be radioactively tagged with Fluorine-18 for PET imaging, and fused to luciferases for optical (bioluminescence) detection. Performance will be evaluated and validated using a prototype integrated optical-PET imaging system, OPET. Multimodality probes for optical-PET imaging will be based on diabodies that are dually labeled with 18F for PET detection and fused to luciferases for optical imaging. 1) Two sets of fusion proteins will be built, targeting the cell surface markers CEA or HER2. Coelenterazine-based luciferases and variant forms will be evaluated in combination with native substrate and analogs, in order to obtain two distinct probes recognizing different targets with different spectral signatures. 2) Diabody-luciferase fusion proteins will be labeled with 18F using amine reactive [18F]-SFB produced using a novel microwave-assisted, one-pot method. 3) Sitespecific, chemoselective radiolabeling methods will be devised, to reduce the chance that radiolabeling will inactivate either the target-binding properties or the bioluminescence properties of the diabody-luciferase fusion proteins. 4) Combined optical and PET imaging of these dual modality probes will be evaluated and validated in vitro and in vivo using a prototype integrated optical-PET imaging system, OPET. Each imaging modality has its strengths and weaknesses. Development and use of dual modality probes allows optical imaging to benefit from the localization and quantitation offered by the PET mode, and enhances the PET imaging by enabling simultaneous detection of more than one probe.

  13. Metabolomics relative quantitation with mass spectrometry using chemical derivatization and isotope labeling

    DOE PAGES-Beta [OSTI]

    O'Maille, Grace; Go, Eden P.; Hoang, Linh; Want, Elizabeth J.; Smith, Colin; O'Maille, Paul; NordstrÖm, Anders; Morita, Hirotoshi; Qin, Chuan; Uritboonthai, Wilasinee; et al

    2008-01-01

    Comprehensive detection and quantitation of metabolites from a biological source constitute the major challenges of current metabolomics research. Two chemical derivatization methodologies, butylation and amination, were applied to human serum for ionization enhancement of a broad spectrum of metabolite classes, including steroids and amino acids. LC-ESI-MS analysis of the derivatized serum samples provided a significant signal elevation across the total ion chromatogram to over a 100-fold increase in ionization efficiency. It was also demonstrated that derivatization combined with isotopically labeled reagents facilitated the relative quantitation of derivatized metabolites from individual as well as pooled samples.

  14. .sup.123m Te-Labeled biochemicals and method of preparation

    DOE Patents [OSTI]

    Knapp, Jr., Furn F.

    1980-01-01

    A novel class of .sup.123m Te-labeled steroids and amino acids is provided by the method of reacting a .sup.123m Te symmetric diorgano ditelluride with a hydride reducing agent and a source of alkali metal ions to form an alkali metal organo telluride. The alkali metal organo telluride is reacted with a primary halogenated steroidal side chain, amino acid, or amino acid precursor such as hydantoin. The novel compounds are useful as biological tracers and as organal imaging agents.

  15. A method for double-labeling sputum cells for p53 and cytokeratin

    SciTech Connect (OSTI)

    Neft, R.E.; Tierney, L.A.; Belinsky, S.A.

    1995-12-01

    Molecular and immunological techniques may enhance the usefulness of sputum cytology as a screening tool for lung cancer. These techniques may also be useful in detecting and following the early progression of disease from metaplasia to dysplasia, carcinoma in situ, and finally to invasive carcinoma. Longitudinal information on the evolution of these malignant changes in the respiratory epithelium can be gained by prospective study of populations at high risk for lung cancer. This work is significant because double-labeling of cells in sputum with p53 and cytokeratin antibodies facilitates rapid screening of p53 positive neoplastic and preneoplastic lung cells by brightfield and fluorescence microscopy.

  16. Latest Report Shows Cost of Going Solar has Dropped Significantly for 5 Years

    Energy.gov [DOE]

    Lawrence Berkeley National Lab today released the eighth installment of the Tracking the Sun report series, which is funded by the U.S. Department of Energy SunShot Initiative. The report shows that the installed price of distributed solar photovoltaic (PV) power systems in the United States continues to fall precipitously, especially in the last 5 years.

  17. A magnesium-carboxylate framework showing luminescent sensing for CS{sub 2} and nitroaromatic compounds

    SciTech Connect (OSTI)

    Wu, Zhao-Feng; Tan, Bin; Feng, Mei-Ling; Du, Cheng-Feng; Huang, Xiao-Ying

    2015-03-15

    A magnesium metal-organic framework compound, namely [NH{sub 2}(CH{sub 3}){sub 2}][Mg{sub 3}(NDC){sub 2.5}(HCO{sub 2}){sub 2}(DMF){sub 0.75}(H{sub 2}O){sub 0.25}]·1.25DMF·0.75H{sub 2}O (1) (H{sub 2}NDC=1,4-naphthalene dicarboxylic acid, DMF=N,N′-dimethylformamide), has been synthesized in solvothermal conditions and structurally characterized. It features a three-dimensionally anionic framework with aligned channels parallel to the b-axis. Luminescent studies indicated that it showed significant luminescence quenching for carbon disulfide (CS{sub 2}) and nitrobenzene after being activated, at a content of only 3.0 and 0.1 vol% in DMF, respectively. In addition, the activated sample showed sensitive luminescence quenching for 1,3,5-trinitrophenol with a low concentration of 5×10{sup −5} mol/L. - Graphical abstract: Presented is a microporous 3D Mg-MOF, namely, [NH{sub 2}(CH{sub 3}){sub 2}][Mg{sub 3}(NDC){sub 2.5}(HCO{sub 2}){sub 2}(DMF){sub 0.75}(H{sub 2}O){sub 0.25}]·1.25DMF·0.75H{sub 2}O (1) (H{sub 2}NDC=1,4-naphthalene dicarboxylic acid) showing significant luminescence quenching for carbon disulfide and nitrobenzene. - Highlights: • A microporous 3D metal-organic framework based on Mg. • The compound shows significant luminescence quenching for CS{sub 2} and nitrobenzene after activated. • The compound shows sensitive luminescence quenching for 1,3,5-trinitrophenol with a low concentration of 5×10{sup −5} mol/L.

  18. NREL Study Shows Power Grid can Accommodate Large Increase in Wind and

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Solar Generation - News Releases | NREL Study Shows Power Grid can Accommodate Large Increase in Wind and Solar Generation Increased Coordination Over Wider Areas and More Frequent Scheduling Needed; Wind and Solar Significantly Reduce Carbon and Fuel Costs May 20, 2010 The National Renewable Energy Laboratory (NREL) today released an initial study assessing the operational impacts and economics of increased contributions from wind and solar energy producers on the power grid. The Western

  19. NREL Study Shows Renewable Energy Potential in Every State - News Releases

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    | NREL NREL Study Shows Renewable Energy Potential in Every State U.S. RE Technical Potential study produces estimates across technologies July 26, 2012 A new study of renewable energy's technical potential finds that every state in the nation has the space and resource to generate clean energy. The U.S. Department of Energy's National Renewable Energy Laboratory produced the study, U.S. RE Technical Potential, which looks at available renewable resources in each state. It establishes an

  20. NREL report shows E85 gives gas stations a competitive edge - News Releases

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    | NREL report shows E85 gives gas stations a competitive edge Quantity of E85 sold most important factor in profitability July 18, 2008 A study released by the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) can help gas station owners and Clean Cities stakeholders determine whether adding E85 to their product mix can increase profitability. Competition in the fueling station business continues to intensify, particularly as grocery stores and discount clubs

  1. NREL: News - Expo to Show Consumers How to Cut Energy Use

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Expo to Show Consumers How to Cut Energy Use Golden, Colo., June 6, 2002 Consumers can learn how to save energy and money at home from experts who specialize in energy efficient and renewable energy products and services at the Consumer Energy Expo June 21 - 22. The Expo is hosted by the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) in conjunction with Colorado Energy Science Center (CESC). The Expo at NREL's Visitors Center includes exhibits and activities for the

  2. Customizable Interactive Map Shows U.S. Alternative Fuel Data - News

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Releases | NREL Customizable Interactive Map Shows U.S. Alternative Fuel Data Users can find fuel stations, vehicle concentrations, and production plants June 9, 2009 The U.S. Department of Energy (DOE) and the National Renewable Energy Lab (NREL) announced the launch of a comprehensive mapping tool to help industry and government planners implement alternative fuels and advanced vehicles. The new TransAtlas tool combines several different types of geographic data to identify areas with

  3. Pantex-Y-12 resource-sharing shows the benefit of consolidation | National

    National Nuclear Security Administration (NNSA)

    Nuclear Security Administration | (NNSA) Pantex-Y-12 resource-sharing shows the benefit of consolidation Wednesday, March 9, 2016 - 4:51pm Y 12 engineers Tucker Fritz, Sarah Cruise and Damita Mason (seated) accepted temporary assignments at Pantex. Shown with them are Pantex Engineering Manager Joe Papp and CNS Vice President of Engineering Mike Beck. Three Y-12 employees recently completed temporary assignments at Pantex. Y-12 engineers Sarah Cruise, Tucker Fritz and Damita Mason spent

  4. Taking on the Heat in Solar Cells: New Calculations Show Atomic Vibrations

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Hurt Efficiency | U.S. DOE Office of Science (SC) Taking on the Heat in Solar Cells: New Calculations Show Atomic Vibrations Hurt Efficiency Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3081 F:

  5. ORISE: Report shows nuclear engineering graduation rates on the rise in

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    2013 ORISE report shows nuclear engineering graduation rates on the rise in 2013 Number of graduate degrees expected to remain consistent, but undergraduate degrees could see decrease come 2015 FOR IMMEDIATE RELEASE March 3, 2014 FY14-11 OAK RIDGE, Tenn.-The number of college students graduating with majors in nuclear engineering continues to increase, according to a report by the Oak Ridge Institute for Science and Education, which surveyed 32 U.S. universities with nuclear engineering

  6. Saint-Gobain Shows the Way on Effectively Preparing for Energy Savings Assessments

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    As the front runner in the world's habitation markets, Saint-Gobain has set itself the goal of providing innovative solutions to the upcoming challenges of environmental protection and energy saving. - Pierre-André deChalendar, Saint Gobain CEO continued > Saint-Gobain Shows the Way on Effectively Preparing for Energy Savings Assessments Saint-Gobain, a world leader in high-performance materials and glass manufacturing, uses its rich history in energy efficiency and experiences with DOE's

  7. Peptide affinity labels for thrombin and other trypsin-like proteases

    DOE Patents [OSTI]

    Shaw, Elliott N.; Kettner, Charles A.

    1982-03-09

    A peptide affinity label of the formula (I): ##STR1## wherein X is a radical capable of acting as a leaving group in a nucleophilic substitution reaction; A is an aromatic amino acid residue; B is H, or a C.sub.1 -C.sub.4 alkyl group, or aryl; Y is selected from the group consisting of hydrogen, aroyl, C.sub.1 -C.sub.6 acyl, and Q--(A)--.sub.n, wherein Q=hydrogen, aroyl, or C.sub.1 -C.sub.6 acyl, n=1-10, A is an amino acid residue selected from the aliphatic, hydroxy-containing, carboxylic acid group, and amide-thereof-containing, aromatic, sulfur-containing and imino-containing amino acids; and wherein J is selected from the group consisting of --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --,--CH.sub.2 --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- and --CH(OH)--CH.sub.2. The affinity label is useful for irreversibly inactivating thrombin and trypsin-like enzymes and may be used as a potential anticlotting agent.

  8. Made with Renewable Energy: How and Why Companies are Labeling Consumer Products

    SciTech Connect (OSTI)

    Baker Brannan, D.; Heeter, J.; Bird, L.

    2012-03-01

    Green marketing--a marketing strategy highlighting the environmental attributes of a product, often through the use of labels or logos--dates back to the 1970s. It did not proliferate until the 1990s, however, when extensive market research identified a rapidly growing group of consumers with a heightened concern for the environment. This group expressed not only a preference for green products but also a willingness to pay a premium for such products. The response was a surge in green marketing that lasted through the early 1990s. This report discusses the experience of companies that communicate to consumers that their products are 'made with renewable energy.' For this report, representatives from 20 companies were interviewed and asked to discuss their experiences marketing products produced using renewable energy. The first half of this report provides an overview of the type of companies that have labeled products or advertised them as being made with renewable energy. It also highlights the avenues companies use to describe their use of renewable energy. The second half of the report focuses on the motivations for making on-product claims about the use of renewable energy and the challenges in doing so.

  9. Peptide affinity labels for thrombin and other trypsin-like proteases

    DOE Patents [OSTI]

    Shaw, E.N.; Kettner, C.A.

    1982-03-09

    A peptide affinity label is disclosed of the formula (I): as given in the patent wherein X is a radical capable of acting as a leaving group in a nucleophilic substitution reaction; A is an aromatic amino acid residue; B is H, or a C[sub 1]--C[sub 4] alkyl group, or aryl; Y is selected from the group consisting of hydrogen, aroyl, C[sub 1]--C[sub 6] acyl, and Q--(A)--[sub n], wherein Q = hydrogen, aroyl, or C[sub 1]--C[sub 6] acyl, n = 1--10, A is an amino acid residue selected from the aliphatic, hydroxy-containing, carboxylic acid group, and amide-thereofcontaining, aromatic, sulfur-containing and imino-containing amino acids; and wherein J is selected from the group consisting of --CH[sub 2]--, --CH[sub 2]--CH[sub 2]--, --CH[sub 2]--CH[sub 2]--CH[sub 2]--, --CH[double bond]CH-- and --CH(OH)--CH[sub 2]. The affinity label is useful for irreversibly inactivating thrombin and trypsin-like enzymes and may be used as a potential anticlotting agent. 2 figs.

  10. Summary Notes from 28 May 2008 Generic Technical Issue Discussion on Estimating Waste Inventory and Waste Tank Characterization

    Office of Environmental Management (EM)

    8, 2008 Page 1 of 8 Summary Notes from 28 May 2008 Generic Technical Issue Discussion on Estimating Waste Inventory and Waste Tank Characterization Attendees: Representatives from Department of Energy-Headquarters (DOE-HQ) and the U.S. Nuclear Regulatory Commission staff (NRC) met at the DOE offices in Germantown, Maryland on 28 May 2008. Representatives from Department of Energy- Savannah River (DOE-SR), Department of Energy-Richland (DOE-RL), and Department of Energy-River Protection (DOE-ORP)

  11. Pennsylvania and West Virginia show largest increases in natural gas proved reserves

    U.S. Energy Information Administration (EIA) (indexed site)

    Pennsylvania and West Virginia show largest increases in natural gas proved reserves U.S. natural gas proved reserves have hit an all-time high...with Pennsylvania and West Virginia accounting for 70% of the increase ...according to the U.S. Energy Information Administration. In a new report, EIA says that U.S. proved reserves of natural gas reached a record 354 trillion cubic feet at the end of 2013. That's up 10% from the year before. Proved reserves are those volumes of natural gas that

  12. Cytoplasmic Domain Structures of Kir2.1 and Kir3.1 Shows Sites for

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    Modulating Gating and Rectification Cytoplasmic Domain Structures of Kir2.1 and Kir3.1 Shows Sites for Modulating Gating and Rectification Scott Pegan1, Christine Arrabit2, Wei Zhou1, Witek Kwiatkowski1, Anthony Collins3, Paul Slesinger2 and Senyon Choe1 Structural Biology1 and Peptide Biology2 Laboratories, The Salk Institute, La Jolla, Ca 92037; Department of Pharmaceutical Sciences3, College of Pharmacy, Oregon State University, Corvallis, OR 97331 Figure 1. Kir2.1 cytoplasmic domain's

  13. KCP shows off the fun side of science | National Nuclear Security

    National Nuclear Security Administration (NNSA)

    Administration | (NNSA) shows off the fun side of science Friday, May 9, 2014 - 3:23pm From liquid nitrogen to the 3D simulation room, students were immersed in hands-on science fun at this year's Take Your Child To Work Day at the Kansas City Plant. "We are proud of the work we do, and we welcome any opportunity to share the story of our mission." said Mark Holecek, Kansas City Field Office Manager. "As a parent, I think it is even more important that we share our scientific

  14. SRS 'teach-ins' show why math and science are cool | National Nuclear

    National Nuclear Security Administration (NNSA)

    Security Administration | (NNSA) 'teach-ins' show why math and science are cool Thursday, March 13, 2014 - 4:00pm More than 40 engineers, scientists and technicians from the Savannah River Site recently brought creative science- and engineering-based demonstrations to more than 3,000 middle school students, captivating their minds with things like flying objects and robotic creatures to give them a broader understanding of the field of engineering. Over a two-week period, employees of SRS

  15. NREL Report Shows U.S. Solar Photovoltaic Costs Continuing to Fall in 2016

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    - News Releases | NREL NREL Report Shows U.S. Solar Photovoltaic Costs Continuing to Fall in 2016 September 28, 2016 chart of solar pv costs from q4 2009 to q1 2016 NREL U.S. PV system cost benchmarks, from the fourth quarter of 2009 to the first quarter of 2016 The modeled costs to install solar photovoltaic (PV) systems continued to decline in the first quarter of 2016 in the U.S. residential, commercial, and utility-scale sectors, according to updated benchmarks from the Energy

  16. BnNHL18A shows a localization change by stress-inducing chemical treatments

    SciTech Connect (OSTI)

    Lee, Suk-Bae; Ham, Byung-Kook; Park, Jeong Mee; Kim, Young Jin; Paek, Kyung-Hee . E-mail: khpaek95@korea.ac.kr

    2006-01-06

    The two genes, named BnNHL18A and BnNHL18B, showing sequence homology with Arabidopsis NDR1/HIN1-like (NHL) genes, were isolated from cDNA library prepared with oilseed rape (Brassica napus) seedlings treated with NaCl. The transcript level of BnNHL18A was increased by sodium chloride, ethephon, hydrogen peroxide, methyl jasmonate, or salicylic acid treatment. The coding regions of BnNHL18A and BnNHL18B contain a sarcolipin (SLN)-like sequence. Analysis of the localization of smGFP fusion proteins showed that BnNHL18A is mainly localized to endoplasmic reticulum (ER). This result suggests that the SLN-like sequence plays a role in retaining proteins in ER membrane in plants. In response to NaCl, hydrogen peroxide, ethephon, and salicylic acid treatments, the protein localization of BnNHL18A was changed. Our findings suggest a common function of BnNHL18A in biotic and abiotic stresses, and demonstrate the presence of the shared mechanism of protein translocalization between the responses to plant pathogen and to osmotic stress.

  17. Rethinking conventional field development: 3-D shows direct detection of new reserves

    SciTech Connect (OSTI)

    Sibley, D. ); Mastoris, S. )

    1993-09-01

    Accurate well to seismic ties of several producing sands and analyses of reservoir characters have revealed hidden reserves in an aging field that was previously determined to be uneconomic. The combination of a recent three-dimensional survey shot over Eugene Island Blocks 338 and 339, Gulf of Mexico, and new interactive workstation technology were instrumental in identifying swept and unswept portions of different oil reservoirs and allowed new infill wells to pinpoint key targets. Amplitudes were extracted along mapped horizons, which showed lateral variations in the reservoir properties, identifying zones where the waterfront had passed through (deterioration in amplitudes) and areas it had missed (strong amplitudes). For one of the successful wells, overlaying structural contours on the amplitude map showed that much of the oil could be recovered by drilling west and up to 30 m downdip from the current tilted oil/water contact-counterintuitive to traditional field development. Net pay (detuned, composite isopach) maps were constructed by calibrating amplitudes to pay thicknesses. The top and base of these net pay surfaces were displayed in geologic cross sections to direct the horizontal paths of subsequent wells. The result was a 100% success rate in five out of five development wells, to date. The wells are producing between 5740-9250 bbl/day, for Chevron and its operating partner, Texaco. This economic scenario directly resulted in a [open quotes]turnaround[close quotes] decision to keep what was once thought to be a B-rated property.

  18. Fibroblasts maintained in 3 dimensions show a better differentiation state and higher sensitivity to estrogens

    SciTech Connect (OSTI)

    Montani, Claudia; Steimberg, Nathalie; Boniotti, Jennifer; Biasiotto, Giorgio; Zanella, Isabella; Diafera, Giuseppe; Biunno, Ida; Caimi, Luigi; Mazzoleni, Giovanna; Di Lorenzo, Diego

    2014-11-01

    Cell differentiation and response to hormonal signals were studied in a 3D environment on an in-house generated mouse fibroblast cell line expressing a reporter gene under the control of estrogen responsive sequences (EREs). 3D cell culture conditions were obtained in a Rotary Cell Culture System; (RCCS™), a microgravity based bioreactor that promotes the aggregation of cells into multicellular spheroids (MCS). In this bioreactor the cells maintained a better differentiated phenotype and more closely resembled in vivo tissue. The RCCS™ cultured fibroblasts showed higher expression of genes regulating cell assembly, differentiation and hormonal functions. Microarray analysis showed that genes related to cell cycle, proliferation, cytoskeleton, migration, adhesion and motility were all down-regulated in 3D as compared to 2D conditions, as well as oncogene expression and inflammatory cytokines. Controlled remodeling of ECM, which is an essential aspect of cell organization, homeostasis and tissue was affected by the culture method as assessed by immunolocalization of β-tubulin. Markers of cell organization, homeostasis and tissue repair, metalloproteinase 2 (MMP2) and its physiological inhibitor (TIMP4) changed expression in association with the relative formation of cell aggregates. The fibroblasts cultured in the RCCS™ maintain a better responsiveness to estrogens, measured as expression of ERα and regulation of an ERE-dependent reporter and of the endogenous target genes CBP, Rarb, MMP1 and Dbp. Our data highlight the interest of this 3D culture model for its potential application in the field of cell response to hormonal signals and the pharmaco-toxicological analyses of chemicals and natural molecules endowed of estrogenic potential. - Highlights: • We here characterized the first cell line derived from an estrogen reporter mouse. • In the RCCS cells express an immortalized behavior but not a transformed phenotype. • The RCCS provides a system for

  19. Lithium inclusion in indium metal-organic frameworks showing increased surface area and hydrogen adsorption

    SciTech Connect (OSTI)

    Bosch, Mathieu; Zhang, Muwei; Feng, Dawei; Yuan, Shuai; Wang, Xuan; Chen, Ying-Pin; Zhou, Hong-Cai

    2014-12-01

    Investigation of counterion exchange in two anionic In-Metal-Organic Frameworks (In-MOFs) showed that partial replacement of disordered ammonium cations was achieved through the pre-synthetic addition of LiOH to the reaction mixture. This resulted in a surface area increase of over 1600% in (Li [In(1,3 − BDC){sub 2}]){sub n} and enhancement of the H{sub 2} uptake of approximately 275% at 80 000 Pa at 77 K. This method resulted in frameworks with permanent lithium content after repeated solvent exchange as confirmed by inductively coupled plasma mass spectrometry. Lithium counterion replacement appears to increase porosity after activation through replacement of bulkier, softer counterions and demonstrates tuning of pore size and properties in MOFs.

  20. Note: The design of thin gap chamber simulation signal source based on field programmable gate array

    SciTech Connect (OSTI)

    Hu, Kun; Wang, Xu; Li, Feng; Jin, Ge; Lu, Houbing; Liang, Futian

    2015-01-15

    The Thin Gap Chamber (TGC) is an important part of ATLAS detector and LHC accelerator. Targeting the feature of the output signal of TGC detector, we have designed a simulation signal source. The core of the design is based on field programmable gate array, randomly outputting 256-channel simulation signals. The signal is generated by true random number generator. The source of randomness originates from the timing jitter in ring oscillators. The experimental results show that the random number is uniform in histogram, and the whole system has high reliability.

  1. Note: A new regulation method of stable operation of high power cathode ion source

    SciTech Connect (OSTI)

    Jiang, C. C.; Xie, Y. H. Hu, C. D.; Xie, Y. L.; Liu, S.; Liang, L. Z.; Liu, Z. M.

    2015-05-15

    The hot cathode ion source will tend to be unstable when operated with high power and long pulse. In order to achieve stable operation, a new regulation method based on the arc power (discharge power) feedback control was designed and tested on the hot cathode ion source test bed with arc discharge and beam extraction. The results show that the new regulation method can achieve stable arc discharge and beam extraction. It verifies the success of feedback control of arc source with arc power.

  2. New water soluble heterometallic complex showing unpredicted coordination modes of EDTA

    SciTech Connect (OSTI)

    Mudsainiyan, R.K. Jassal, A.K.; Chawla, S.K.

    2015-10-15

    A mesoporous 3D polymeric complex (I) having formula ([Zr(IV)O-μ{sup 3}-(EDTA)Fe(III)OH]·H{sub 2}O){sub n} has been crystallized and characterized by various techniques. Single-crystal X-ray diffraction analysis revealed that complex (I) crystallized in chiral monoclinic space group Cc (space group no. 9) with unexpected coordination modes of EDTA and mixture of two transition metal ions. In this complex, the coordination number of Zr(IV) ion is seven where four carboxylate oxygen atoms, two nitrogen atoms, one oxide atom are coordinating with Zr(IV). Fe(III) is four coordinated and its coordination environment is composed of three different carboxylic oxygen atoms from three different EDTA and one oxygen atom of –OH group. The structure consists of 4-c and 16-c (2-nodal) net with new topology and point symbol for net is (3{sup 36}·4{sup 54}·5{sup 30})·(3{sup 6}). TGA study and XRPD pattern showed that the coordination polymer is quite stable even after losing water molecule and –OH ion. Quenching behavior in fluorescence of ligand is observed by complexation with transition metal ions is due to n–π⁎ transition. The SEM micrograph shows the morphology of complex (I) exhibits spherical shape with size ranging from 50 to 280 nm. The minimum N{sub 2} (S{sub BET}=8.7693 m{sup 2}/g) and a maximum amount of H{sub 2} (high surface area=1044.86 m{sup 2}/g (STP)) could be adsorbed at 77 K. From DLS study, zeta potential is calculated i.e. −7.94 shows the negative charges on the surface of complex. Hirshfeld surface analysis and fingerprint plots revealed influence of weak or non bonding interactions in crystal packing of complex. - Graphical abstract: The complex (I) crystallized with unexpected coordination modes of EDTA having 4-c, 16-c net with new topology and point symbol is (3{sup 36}·4{sup 54}·5{sup 30})·(3{sup 6}). TGA study and XRPD pattern proved its stability with high preference of H{sub 2} uptake by complex. - Highlights: • 3D complex

  3. Energy-Efficiency Labels and Standards: A Guidebook forAppliances, Equipment, and Lighting - 2nd Edition

    SciTech Connect (OSTI)

    Wiel, Stephen; McMahon, James E.

    2005-04-28

    Energy-performance improvements in consumer products are an essential element in any government's portfolio of energy-efficiency and climate change mitigation programs. Governments need to develop balanced programs, both voluntary and regulatory, that remove cost-ineffective, energy-wasting products from the marketplace and stimulate the development of cost-effective, energy-efficient technology. Energy-efficiency labels and standards for appliances, equipment, and lighting products deserve to be among the first policy tools considered by a country's energy policy makers. The U.S. Agency for International Development (USAID) and several other organizations identified on the cover of this guidebook recognize the need to support policy makers in their efforts to implement energy-efficiency standards and labeling programs and have developed this guidebook, together with the Collaborative Labeling and Appliance Standards Program (CLASP), as a primary reference. This second edition of the guidebook was prepared over the course of the past year, four years after the preparation of the first edition, with a significant contribution from the authors and reviewers mentioned previously. Their diligent participation helps maintain this book as the international guidance tool it has become. The lead authors would like to thank the members of the Communications Office of the Environmental Energy Technologies Division, Lawrence Berkeley National Laboratory for their support in the development, production, and distribution of the guidebook. This guidebook is designed as a manual for government officials and others around the world responsible for developing, implementing, enforcing, monitoring, and maintaining labeling and standards setting programs. It discusses the pros and cons of adopting energy-efficiency labels and standards and describes the data, facilities, and institutional and human resources needed for these programs. It provides guidance on the design, development

  4. Method to detect the end-point for PCR DNA amplification using an ionically labeled probe and measuring impedance change

    DOE Patents [OSTI]

    Miles, Robin R.; Belgrader, Phillip; Fuller, Christopher D.

    2007-01-02

    Impedance measurements are used to detect the end-point for PCR DNA amplification. A pair of spaced electrodes are located on a surface of a microfluidic channel and an AC or DC voltage is applied across the electrodes to produce an electric field. An ionically labeled probe will attach to a complementary DNA segment, and a polymerase enzyme will release the ionic label. This causes the conductivity of the solution in the area of the electrode to change. This change in conductivity is measured as a change in the impedance been the two electrodes.

  5. Technical Note: Response measurement for select radiation detectors in magnetic fields

    SciTech Connect (OSTI)

    Reynolds, M.; Fallone, B. G.; Rathee, S.

    2015-06-15

    Purpose: Dose response to applied magnetic fields for ion chambers and solid state detectors has been investigated previously for the anticipated use in linear acceleratormagnetic resonance devices. In this investigation, the authors present the measured response of selected radiation detectors when the magnetic field is applied in the same direction as the radiation beam, i.e., a longitudinal magnetic field, to verify previous simulation only data. Methods: The dose response of a PR06C ion chamber, PTW60003 diamond detector, and IBA PFD diode detector is measured in a longitudinal magnetic field. The detectors are irradiated with buildup caps and their long axes either parallel or perpendicular to the incident photon beam. In each case, the magnetic field dose response is reported as the ratio of detector signals with to that without an applied longitudinal magnetic field. The magnetic field dose response for each unique orientation as a function of magnetic field strength was then compared to the previous simulation only studies. Results: The measured dose response of each detector in longitudinal magnetic fields shows no discernable response up to near 0.21 T. This result was expected and matches the previously published simulation only results, showing no appreciable dose response with magnetic field. Conclusions: Low field longitudinal magnetic fields have been shown to have little or no effect on the dose response of the detectors investigated and further lend credibility to previous simulation only studies.

  6. Slow light Mach-Zehnder interferometer as label-free biosensor with scalable sensitivity

    DOE PAGES-Beta [OSTI]

    Qin, Kun; Hu, Shuren; Retterer, Scott T.; Kravchenko, Ivan I.; Weiss, Sharon M.

    2016-02-05

    Our design, fabrication, and characterization of a label-free Mach–Zehnder interferometer (MZI) optical biosensor that incorporates a highly dispersive one-dimensional (1D) photonic crystal in one arm are presented. The sensitivity of this slow light MZI-based sensor scales with the length of the slow light photonic crystal region. The numerically simulated sensitivity of a MZI sensor with a 16 μm long slow light region is 115,000 rad/RIU-cm, which is sevenfold higher than traditional MZI biosensors with millimeter-length sensing regions. Moreover, the experimental bulk refractive index detection sensitivity of 84,000 rad/RIU-cm is realized and nucleic acid detection is also demonstrated.

  7. Metal-isonitrile adducts for preparing radionuclide complexes for labelling and imaging agents

    DOE Patents [OSTI]

    Jones, Alun G.; Davison, Alan; Abrams, Michael J.

    1987-01-01

    A method for preparing a coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta is disclosed. The method comprises preparing a soluble metal adduct of said isonitrile ligand by admixing said ligand with a salt of a displaceable metal having a complete d-electron shell selected from the group consisting of Zn, Ga, Cd, In, Sn, Hg, Tl, Pb and Bi to form a soluble metal-isonitrile salt, and admixing said metal isonitrile salt with a salt comprising said radioactive metal in a suitable solvent to displace said displaceable metal with the radioactive metal thereby forming said coordination. The complex is useful as a diagnostic agent for labelling liposomes or vesicles, and selected living cells containing lipid membranes, such as blood clots, myocardial tissue, gall bladder tissue, etc.

  8. Portable microfluidic raman system for rapid, label-free early disease signature detection

    SciTech Connect (OSTI)

    Wu, Meiye; Davis, Ryan Wesley; Hatch, Anson

    2015-09-01

    In the early stages of infection, patients develop non-specific or no symptoms at all. While waiting for identification of the infectious agent, precious window of opportunity for early intervention is lost. The standard diagnostics require affinity reagents and sufficient pathogen titers to reach the limit of detection. In the event of a disease outbreak, triaging the at-risk population rapidly and reliably for quarantine and countermeasure is more important than the identification of the pathogen by name. To expand Sandia's portfolio of Biological threat management capabilities, we will utilize Raman spectrometry to analyze immune subsets in whole blood to rapidly distinguish infected from non-infected, and bacterial from viral infection, for the purpose of triage during an emergency outbreak. The goal of this one year LDRD is to determine whether Raman spectroscopy can provide label-free detection of early disease signatures, and define a miniaturized Raman detection system meeting requirements for low- resource settings.

  9. Rational Conversion of Affinity Reagents into Label-Free Sensors for Peptide Motifs by Designed Allostery

    SciTech Connect (OSTI)

    Huang, Jin; Koide, Shohei

    2010-05-25

    Optical biosensors for short peptide motifs, an important class of biomarkers, have been developed based on 'affinity clamps', a new class of recombinant affinity reagents. Affinity clamps are engineered by linking a peptide-binding domain and an antibody mimic domain based on the fibronectin type III scaffold, followed by optimization of the interface between the two. This two-domain architecture allows for the design of allosteric coupling of peptide binding to fluorescence energy transfer between two fluorescent proteins attached to the affinity clamp. Coupled with high affinity and specificity of the underlying affinity clamps and rationally designed mutants with different sensitivity, peptide concentrations in crude cell lysate were determined with a low nanomolar detection limit and over 3 orders of magnitude. Because diverse affinity clamps can be engineered, our strategy provides a general platform to generate a repertoire of genetically encoded, label-free sensors for peptide motifs.

  10. Tin-117m-labeled stannic (Sn.sup.4+) chelates

    DOE Patents [OSTI]

    Srivastava, Suresh C.; Meinken, George E.; Richards, Powell

    1985-01-01

    The radiopharmaceutical reagents of this invention and the class of Tin-117m radiopharmaceuticals are therapeutic and diagnostic agents that incorporate gamma-emitting nuclides that localize in bone after intravenous injection in mammals (mice, rats, dogs, and rabbits). Images reflecting bone structure or function can then be obtained by a scintillation camera that detects the distribution of ionizing radiation emitted by the radioactive agent. Tin-117m-labeled chelates of stannic tin localize almost exclusively in cortical bone. Upon intravenous injection of the reagent, the preferred chelates are phosphonate compounds, preferable, PYP, MDP, EHDP, and DTPA. This class of reagents is therapeutically and diagnostically useful in skeletal scintigraphy and for the radiotherapy of bone tumors and other disorders.

  11. Assessment of the Impacts of Standards and Labeling Programs inMexico (four products).

    SciTech Connect (OSTI)

    Sanchez, Itha; Pulido, Henry; McNeil, Michael A.; Turiel, Isaac; della Cava, Mirka

    2007-06-12

    This study analyzes impacts from energy efficiency standards and labeling in Mexico from 1994 through 2005 for four major products: household refrigerators, room air conditioners, three-phase (squirrel cage) induction motors, and clothes washers. It is a retrospective analysis, seeking to assess verified impacts on product efficiency in the Mexican market in the first ten years after standards were implemented. Such an analysis allows the Mexican government to compare actual to originally forecast program benefits. In addition, it provides an extremely valuable benchmark for other countries considering standards, and to the energy policy community as a whole. The methodology for evaluation begins with historical test data taken for a large number of models of each product type between 1994 and 2005. The pre-standard efficiency of models in 1994 is taken as a baseline throughout the analysis. Model efficiency data were provided by an independent certification laboratory (ANCE), which tested products as part of the certification and enforcement mechanism defined by the standards program. Using this data, together with economic and market data provided by both government and private sector sources, the analysis considers several types of national level program impacts. These include: Energy savings; Environmental (emissions) impacts, and Net financial impacts to consumers, manufacturers and utilities. Energy savings impacts are calculated using the same methodology as the original projections, allowing a comparison. Other impacts are calculated using a robust and sophisticated methodology developed by the Instituto de Investigaciones Electricas (IIE) and Lawrence Berkeley National Laboratory (LBNL), in a collaboration supported by the Collaborative Labeling and Standards Program (CLASP).

  12. Note: Fast compact laser shutter using a direct current motor and three-dimensional printing

    SciTech Connect (OSTI)

    Zhang, Grace H. Braverman, Boris; Kawasaki, Akio; Vuletić, Vladan

    2015-12-15

    We present a mechanical laser shutter design that utilizes a direct current electric motor to rotate a blade which blocks and unblocks a light beam. The blade and the main body of the shutter are modeled with computer aided design (CAD) and are produced by 3D printing. Rubber flaps are used to limit the blade’s range of motion, reducing vibrations and preventing undesirable blade oscillations. At its nominal operating voltage, the shutter achieves a switching speed of (1.22 ± 0.02) m/s with 1 ms activation delay and 10 μs jitter in its timing performance. The shutter design is simple, easy to replicate, and highly reliable, showing no failure or degradation in performance over more than 10{sup 8} cycles.

  13. Notes on the efficacy of wet versus dry screening of fly ash

    SciTech Connect (OSTI)

    Valentim, B.; Hower, J.C.; Flores, D.; Guedes, A.

    2008-08-15

    The methodology used to obtain fly ash subsamples of different sizes is generally based on wet or dry sieving methods. However, the worth of such methods is not certain if the methodology applied is not mentioned in the analytical procedure. After performing a fly ash mechanical dry, sieving, the authors compared those results with the ones obtained by laser diffraction on the same samples and found unacceptable discrepancies. A preliminary, study of a wet sieving analysis carried out on an economizer fly ash sample showed that this method was more effective than the dry sieving. The importance of standardizing the way samples are handled, pretreated and presented to the instrument of analysis are suggested and interlaboratory reproducibility trials are needed to create a common standard methodology to obtain large amounts of fly ash size fraction subsamples.

  14. Note: A novel technique for analysis of aqueous solutions by laser-induced breakdown spectroscopy

    SciTech Connect (OSTI)

    Rusak, D. A.; Bell, Z. T.; Anthony, T. P.

    2015-11-15

    Surface-enhanced Raman spectroscopy (SERS) substrates typically consist of gold or silver nanoparticles deposited on a non-conductive substrate. In Raman spectroscopy, the nanoparticles produce an enhancement of the electromagnetic field which, in turn, leads to greater electronic excitation of molecules in the local environment. Here, we show that these same surfaces can be used to enhance the signal-to-noise ratio obtained in laser-induced breakdown spectroscopy of aqueous solutions. In this case, the SERS substrates not only lower breakdown thresholds and lead to more efficient plasma initiation but also provide an appropriately wettable surface for the deposition of the liquid. We refer to this technique as surface-enhanced laser-induced breakdown spectroscopy.

  15. Note: Directly measuring the direct digital synthesizer frequency chirp-rate for an atom interferometer

    SciTech Connect (OSTI)

    Tao, Juan-Juan; Zhou, Min-Kang E-mail: zmk@hust.edu.cn; Zhang, Qiao-Zhen; Cui, Jia-Feng; Duan, Xiao-Chun; Shao, Cheng-Gang; Hu, Zhong-Kun E-mail: zmk@hust.edu.cn

    2015-09-15

    During gravity measurements with Raman type atom interferometry, the frequency of the laser used to drive Raman transition is scanned by chirping the frequency of a direct digital synthesizer (DDS), and the local gravity is determined by precisely measuring the chip rate α of DDS. We present an effective method that can directly evaluate the frequency chirp rate stability of our DDS. By mixing a pair of synchronous linear sweeping signals, the chirp rate fluctuation is precisely measured with a frequency counter. The measurement result shows that the relative α instability can reach 5.7 × 10{sup −11} in 1 s, which is neglectable in a 10{sup −9} g level atom interferometry gravimeter.

  16. Note: Calibration of atomic force microscope cantilevers using only their resonant frequency and quality factor

    SciTech Connect (OSTI)

    Sader, John E.; Friend, James R.

    2014-11-15

    A simplified method for calibrating atomic force microscope cantilevers was recently proposed by Sader et al. [Rev. Sci. Instrum. 83, 103705 (2012); Sec. III D] that relies solely on the resonant frequency and quality factor of the cantilever in fluid (typically air). This method eliminates the need to measure the hydrodynamic function of the cantilever, which can be time consuming given the wide range of cantilevers now available. Using laser Doppler vibrometry, we rigorously assess the accuracy of this method for a series of commercially available cantilevers and explore its performance under non-ideal conditions. This shows that the simplified method is highly accurate and can be easily implemented to perform fast, robust, and non-invasive spring constant calibration.

  17. Note: Decoupling design for high frequency piezoelectric ultrasonic transducers with their clamping connections

    SciTech Connect (OSTI)

    Wang, F. J. Liang, C. M.; Tian, Y. L.; Zhao, X. Y.; Zhang, D. W.; Zhang, H. J.

    2015-12-15

    This work presents the flexure-mechanism based decoupling design between high frequency piezoelectric ultrasonic transducers and their clamping connections to improve ultrasonic energy transmission efficiency. The ring, prismatic beam, and circular notched hinge based flanges were presented, and the crucial geometric dimensions of the transducers with the flexure decoupling flanges were determined. Finite element analysis (FEA) was carried out to investigate the dynamic characteristics of the transducers. Finally, experiments were conducted to examine and verify the effects of the proposed decoupling flanges. FEA and experimental results show that smaller frequency deviations and larger tip displacement amplitudes have been achieved by using the transducers with the flexure flanges compared with the transducer with a rigid ring-type flange, and thus the ultrasonic transmission efficiency can be improved through the flexure flanges.

  18. Technical Note: On the use of nudging for aerosol-climate model intercomparison studies

    DOE PAGES-Beta [OSTI]

    Zhang, K.; Wan, H.; Liu, X.; Ghan, S. J.; Kooperman, G. J.; Ma, P.-L.; Rasch, P. J.

    2014-04-24

    Nudging is an assimilation technique widely used in the development and evaluation of climate models. Constraining the simulated wind and temperature fields using global weather reanalysis facilitates more straightforward comparison between simulation and observation, and reduces uncertainties associated with natural variabilities of the large-scale circulation. On the other hand, the forcing introduced by nudging can be strong enough to change the basic characteristics of the model climate. In the paper we show that for the Community Atmosphere Model version 5, due to the systematic temperature bias in the standard model and the sensitivity of simulated ice formation to anthropogenic aerosolmore » concentration, nudging towards reanalysis results in substantial reductions in the ice cloud amount and the impact of anthropogenic aerosols on longwave cloud forcing. In order to reduce discrepancies between the nudged and unconstrained simulations and meanwhile take the advantages of nudging, two alternative experimentation methods are evaluated. The first one constrains only the horizontal winds. The second method nudges both winds and temperature, but replaces the long-term climatology of the reanalysis by that of the model. Results show that both methods lead to substantially improved agreement with the free-running model in terms of the top-of-atmosphere radiation budget and cloud ice amount. The wind-only nudging is more convenient to apply, and provides higher correlations of the wind fields, geopotential height and specific humidity between simulation and reanalysis. This suggests nudging the horizontal winds but not temperature is a good strategy for the investigation of aerosol indirect effects through ice clouds, since it provides well-constrained meteorology without strongly perturbing the model's mean climate.« less

  19. Technical Note: On the Use of Nudging for Aerosol-Climate Model Intercomparison Studies

    SciTech Connect (OSTI)

    Zhang, Kai; Wan, Hui; Liu, Xiaohong; Ghan, Steven J.; Kooperman, G. J.; Ma, Po-Lun; Rasch, Philip J.; Neubauer, David; Lohmann, U.

    2014-08-26

    Nudging is an assimilation technique widely used in the development and evaluation of climate models. Con- straining the simulated wind and temperature fields using global weather reanalysis facilitates more straightforward comparison between simulation and observation, and reduces uncertainties associated with natural variabilities of the large-scale circulation. On the other hand, the artificial forcing introduced by nudging can be strong enough to change the basic characteristics of the model climate. In the paper we show that for the Community Atmosphere Model version 5, due to the systematic temperature bias in the standard model and the relatively strong sensitivity of homogeneous ice nucleation to aerosol concentration, nudging towards reanalysis results in substantial reductions in the ice cloud amount and the impact of anthropogenic aerosols on longwave cloud forcing. In order to reduce discrepancies between the nudged and unconstrained simulations and meanwhile take the advantages of nudging, two alternative experimentation methods are evaluated. The first one constrains only the horizontal winds. The second method nudges both winds and temperature, but replaces the long-term climatology of the reanalysis by that of the model. Results show that both methods lead to substantially improved agreement with the free-running model in terms of the top-of-atmosphere radiation budget and cloud ice amount. The wind-only nudging is more convenient to apply, and provides higher correlations of the wind fields, geopotential height and specific humidity between simulation and reanalysis. This suggests that nudging the horizontal winds but not temperature is a good strategy, especially for studies that involve both warm and cold clouds.

  20. Magnetism reflectometer study shows LiF layers improve efficiency in spin valve devices

    SciTech Connect (OSTI)

    Bardoel, Agatha A; Lauter, Valeria; Szulczewski, Greg J

    2012-01-01

    in the spin valve and enhancing the overall properties of the system. In related work the magnetic properties of the cobalt film and the permalloy Ni{sub 80}Fe{sub 20} were characterized. Cobalt in particular needed attention, as it cannot be grown epitaxially (i.e., deposited) on an organic semiconductor film. Cobalt becomes polycrystalline or amorphous, and this affects its magnetic properties. The data from the first experiment showed that the cobalt layer in the system 'did not have typical magnetic properties,' Lauter said. 'The results showed that the cobalt had low magnetization. To improve the efficiency, the cobalt magnetization should be much higher. So this experiment helped us to improve the growth conditions and to get a cobalt layer with better magnetic properties.' In a subsequent experiment the researchers increased the magnetization of the cobalt, and a follow-up paper is in progress.

  1. Technical Note: On the use of nudging for aerosol–climate model intercomparison studies

    DOE PAGES-Beta [OSTI]

    Zhang, K.; Wan, H.; Liu, X.; Ghan, S. J.; Kooperman, G. J.; Ma, P.-L.; Rasch, P. J.; Neubauer, D.; Lohmann, U.

    2014-08-26

    Nudging as an assimilation technique has seen increased use in recent years in the development and evaluation of climate models. Constraining the simulated wind and temperature fields using global weather reanalysis facilitates more straightforward comparison between simulation and observation, and reduces uncertainties associated with natural variabilities of the large-scale circulation. On the other hand, the forcing introduced by nudging can be strong enough to change the basic characteristics of the model climate. In the paper we show that for the Community Atmosphere Model version 5 (CAM5), due to the systematic temperature bias in the standard model and the sensitivity ofmore » simulated ice formation to anthropogenic aerosol concentration, nudging towards reanalysis results in substantial reductions in the ice cloud amount and the impact of anthropogenic aerosols on long-wave cloud forcing. In order to reduce discrepancies between the nudged and unconstrained simulations, and meanwhile take the advantages of nudging, two alternative experimentation methods are evaluated. The first one constrains only the horizontal winds. The second method nudges both winds and temperature, but replaces the long-term climatology of the reanalysis by that of the model. Results show that both methods lead to substantially improved agreement with the free-running model in terms of the top-of-atmosphere radiation budget and cloud ice amount. The wind-only nudging is more convenient to apply, and provides higher correlations of the wind fields, geopotential height and specific humidity between simulation and reanalysis. Results from both CAM5 and a second aerosol–climate model ECHAM6-HAM2 also indicate that compared to the wind-and-temperature nudging, constraining only winds leads to better agreement with the free-running model in terms of the estimated shortwave cloud forcing and the simulated convective activities. This suggests nudging the horizontal winds but not

  2. Technical Note: Characterization of custom 3D printed multimodality imaging phantoms

    SciTech Connect (OSTI)

    Bieniosek, Matthew F.; Lee, Brian J.; Levin, Craig S.

    2015-10-15

    Purpose: Imaging phantoms are important tools for researchers and technicians, but they can be costly and difficult to customize. Three dimensional (3D) printing is a widely available rapid prototyping technique that enables the fabrication of objects with 3D computer generated geometries. It is ideal for quickly producing customized, low cost, multimodal, reusable imaging phantoms. This work validates the use of 3D printed phantoms by comparing CT and PET scans of a 3D printed phantom and a commercial “Micro Deluxe” phantom. This report also presents results from a customized 3D printed PET/MRI phantom, and a customized high resolution imaging phantom with sub-mm features. Methods: CT and PET scans of a 3D printed phantom and a commercial Micro Deluxe (Data Spectrum Corporation, USA) phantom with 1.2, 1.6, 2.4, 3.2, 4.0, and 4.8 mm diameter hot rods were acquired. The measured PET and CT rod sizes, activities, and attenuation coefficients were compared. A PET/MRI scan of a custom 3D printed phantom with hot and cold rods was performed, with photon attenuation and normalization measurements performed with a separate 3D printed normalization phantom. X-ray transmission scans of a customized two level high resolution 3D printed phantom with sub-mm features were also performed. Results: Results show very good agreement between commercial and 3D printed micro deluxe phantoms with less than 3% difference in CT measured rod diameter, less than 5% difference in PET measured rod diameter, and a maximum of 6.2% difference in average rod activity from a 10 min, 333 kBq/ml (9 μCi/ml) Siemens Inveon (Siemens Healthcare, Germany) PET scan. In all cases, these differences were within the measurement uncertainties of our setups. PET/MRI scans successfully identified 3D printed hot and cold rods on PET and MRI modalities. X-ray projection images of a 3D printed high resolution phantom identified features as small as 350 μm wide. Conclusions: This work shows that 3D printed

  3. Technical Note: On the proton range and nuclear interactions in compounds and mixtures

    SciTech Connect (OSTI)

    Rasouli, Fatemeh S. Masoudi, S. Farhad; Jette, David

    2015-05-15

    Purpose: Range and probability of nonelastic nuclear interactions (NNIs) for protons can be found only for a limited number of compounds and mixtures in nuclear data tables, and the proton-related analytical studies are therefore restricted to those materials for which the data are provided in these documents. In this paper, the authors present general solutions for calculating the proton range and probability of NNIs for desired compounds and mixtures. Methods: Benefiting from the Bragg–Kleeman approximation of mass stopping power, the authors derive a concise formula for calculating the proton range in materials with arbitrary number of constituent elements. Additionally, the authors propose another relation for obtaining the probability of undergoing NNIs which is suggested to be additive. Results: The examination of the formula presented shows that the authors’ method can be considered as general solutions for analytical evaluation of the range in compounds and mixtures. The formula proposed for probability of NNIs is valid for almost every compound except for those materials containing H. It is shown that this formula can be modified so that it covers these materials. Conclusions: The authors present a general analytical method for calculating the range and probability of NNIs for protons which are mathematically easy to handle and valid for desired compounds or mixtures composed of an arbitrary number of constituent elements, including materials of interest for proton radiotherapy purposes.

  4. The Usefulness of Bi-Level Switching; Original Technical Note: November 1998. Revised August, 1999

    SciTech Connect (OSTI)

    Building Technologies Department

    1998-11-01

    California's Title 24 Energy Efficiency Building Standard requires multiple lighting level control in all individual offices. Usually, this requirement is fulfilled using bi-level switching. With bi-level switching, each office occupant is provided with two wall switches near the doorway to control their lights. In a typical installation, one switch would control 1/3 of the fluorescent lamps in the ceiling lighting system, while the other switch would control the remaining 2/3 of the lamps. This allows four possible light levels: OFF, 1/3, 2/3 and FULL lighting. Because it has been required by building code since 1983, bi-level switching is common in California office buildings. However, there is no published evidence showing that occupants sometimes use just one switch rather than just switching on both switches when entering the room. Consequently, some have questioned whether bi-level switching is a necessary or desirable requirement for typical office buildings. In fact, the draft national standard, ASHRAE Standard 90.1-1989K apparently does not require bi-level switching at all.

  5. ADIFOR: Fortran source translation for efficient derivatives. ADIFOR Working Note No. 4

    SciTech Connect (OSTI)

    Bischof, C.; Corliss, G.; Griewank, A.; Hovland, P.; Carle, A.

    1992-07-01

    The numerical methods employed in the solution of many scientific computing problems require the computation of derivatives of a function f: R{sup n} {yields} R{sup m}. Both the accuracy and the computational requirements of the derivative computation are usually of critical importance for the robustness and speed of the numerical method. ADIFOR (Automatic Differentiation In FORtran) is a source translation tool implemented using the data abstractions and program analysis capabilities of the ParaScope Parallel Programming Environment. ADIFOR accepts arbitrary Fortran-77 code defining the computation of a function and writes portable Fortran-77 code for the computation of its derivatives. In contrast to previous approaches, ADIFOR views automatic differentiation as a process of source translation that exploits computational context to reduce the cost of derivative computations. Experimental results show that ADIFOR can handle real-life codes, providing exact derivatives with a running time that is competitive with the standard divided-difference approximations of derivatives and which may perform orders of magnitude faster than divided-differences in cases. The computational scientist using ADIFOR is freed from worrying about the accurate and efficient computation of derivatives, even for complicated ``functions,`` and hence, is able to concentrate on the more important issues of algorithm design or system modeling. 35 refs.

  6. CFL Labeling Harmonization in the United States, China, Brazil andELI Member Countries: Specifications, Testing, and MutualRecognition

    SciTech Connect (OSTI)

    Fridley, David; Lin, Jiang; Denver, Andrea; Biermayer, Peter; Dillavou, Tyler

    2005-07-20

    This report examines critical differences among energy-efficient labeling programs for CFLs in Brazil, China, the United States, and the seven members of the international Efficient Lighting Initiative (ELI) in terms of technical specifications and test procedures, and review issues related to international harmonization of these standards.

  7. Fluorescence energy transfer efficiency in labeled yeast cytochrome c: a rapid screen for ion biocompatibility in aqueous ionic liquids

    SciTech Connect (OSTI)

    Baker, Sheila N; Zhao, Hua; Pandey, Siddharth; Heller, William T; Bright, Frank; Baker, Gary A

    2011-01-01

    A fluorescence energy transfer de-quenching assay was implemented to follow the equilibrium unfolding behaviour of site-specific tetramethylrhodamine-labelled yeast cytochrome c in aqueous ionic liquid solutions; additionally, this approach offers the prospect of naked eye screening for biocompatible ion combinations in hydrated ionic liquids.

  8. Method and kit for the selective labeling of red blood cells in whole blood with TC-99M

    DOE Patents [OSTI]

    Srivastava, Suresh C.; Babich, John W.; Straub, Rita; Richards, Powell

    1988-01-01

    Disclosed herein are a method and kit for the preparation of .sup.99m Tc labeled red blood cells using whole blood in a closed sterile system containing stannous tin in a form such that it will enter the red blood cells and be available therein for the reduction of technetium.

  9. Method and kit for the selective labeling of red blood cells in whole blood with Tc-99m

    DOE Patents [OSTI]

    Srivastava, S.C.; Babich, J.W.; Straub, R.; Richards, P.

    1988-07-05

    Disclosed herein are a method and kit for the preparation of [sup 99m]Tc labeled red blood cells using whole blood in a closed sterile system containing stannous tin in a form such that it will enter the red blood cells and be available for the reduction of technetium. No Drawings

  10. Technical Note: Building a combined cyclotron and MRI facility: Implications for interference

    SciTech Connect (OSTI)

    Hofman, Mark B. M.; Kuijer, Joost P. A.; Ridder, Jan Willem de; Perk, Lars R.; Verdaasdonk, Rudolf M.

    2013-01-15

    Purpose: With the introduction of hybrid PET/MRI systems, it has become more likely that the cyclotron and MRI systems will be located close to each other. This study considered the interference between a cyclotron and a superconducting MRI system. Methods: Interactions between cyclotrons and MRIs are theoretically considered. The main interference is expected to be the perturbation of the magnetic field in the MRI due to switching on or off the magnetic field of the cyclotron. MR imaging is distorted by a dynamic spatial gradient of an external inplane magnetic field larger than 0.5-0.04 {mu}T/m, depending on the specific MR application. From the design of a cyclotron, it is expected that the magnetic fringe field at large distances behaves as a magnetic dipolar field. This allows estimation of the full dipolar field and its spatial gradients from a single measurement. Around an 18 MeV cyclotron (Cyclone, IBA), magnetic field measurements were performed on 5 locations and compared with calculations based upon a dipolar field model. Results: At the measurement locations the estimated and measured values of the magnetic field component and its spatial gradients of the inplane component were compared, and found to agree within a factor 1.1 for the magnetic field and within a factor of 1.5 for the spatial gradients of the field. In the specific case of the 18 MeV cyclotron with a vertical magnetic field and a 3T superconducting whole body MR system, a minimum distance of 20 m has to be considered to prevent interference. Conclusions: This study showed that a dipole model is sufficiently accurate to predict the interference of a cyclotron on a MRI scanner, for site planning purposes. The cyclotron and a whole body MRI system considered in this study need to be placed more than 20 m apart, or magnetic shielding should be utilized.

  11. Comparison of Test Procedures and Energy Efficiency Criteria in Selected International Standards and Labeling Programs for Clothes Washers, Water Dispensers, Vending Machines and CFLs

    SciTech Connect (OSTI)

    Fridley, David; Zheng, Nina; Zhou, Nan

    2010-06-01

    Since the late 1970s, energy labeling programs and mandatory energy performance standards have been used in many different countries to improve the efficiency levels of major residential and commercial equipment. As more countries and regions launch programs covering a greater range of products that are traded worldwide, greater attention has been given to harmonizing the specific efficiency criteria in these programs and the test methods for measurements. For example, an international compact fluorescent light (CFL) harmonization initiative was launched in 2006 to focus on collaboration between Australia, China, Europe and North America. Given the long history of standards and labeling programs, most major energy-consuming residential appliances and commercial equipment are already covered under minimum energy performance standards (MEPS) and/or energy labels. For these products, such as clothes washers and CFLs, harmonization may still be possible when national MEPS or labeling thresholds are revised. Greater opportunity for harmonization exists in newer energy-consuming products that are not commonly regulated but are under consideration for new standards and labeling programs. This may include commercial products such as water dispensers and vending machines, which are only covered by MEPS or energy labels in a few countries or regions. As China continues to expand its appliance standards and labeling programs and revise existing standards and labels, it is important to learn from recent international experiences with efficiency criteria and test procedures for the same products. Specifically, various types of standards and labeling programs already exist in North America, Europe and throughout Asia for products in China's 2010 standards and labeling programs, namely clothes washers, water dispensers, vending machines and CFLs. This report thus examines similarities and critical differences in energy efficiency values, test procedure specifications and other

  12. Pre-Show Checklist

    Energy.gov [DOE]

    Before you leave for your event, you should check that you are prepared and ready to go.  This checklist was designed to remind you of the steps you are required to take before leaving for your event.

  13. Magnesium absorption in human subjects from leafy vegetables, intrinsically labeled with stable /sup 26/Mg

    SciTech Connect (OSTI)

    Schwartz, R.; Spencer, H.; Welsh, J.J.

    1984-04-01

    Collards, turnip greens, leaf lettuce, and spinach, grown in nutrient solution so that their Mg content was 80 to 90% /sup 26/Mg, were tested in ambulant male volunteers stabilized on a constant metabolic diet. The freeze-dried vegetables were incorporated in bran muffins in which the vegetables replaced part of the bran. Bran muffins without vegetables were consumed for breakfast each day. They were also used as a standard test meal to which the vegetable muffins were compared. All subjects participated in three consecutive isotope absorption tests: one of the standard test meal and two of the vegetables. The standard test was carried out after at least 30 days on the controlled diet. Subsequent tests of vegetables followed at 4-wk intervals. Each test meal contained 30 microCi /sup 28/MgCl2 and 50 mg stable /sup 26/Mg, the latter either as the intrinsic label of a test vegetable or as /sup 26/MgCl/sub 2/ in solution taken with the standard bran muffins. Net absorption of both isotopes was measured to establish exchangeability and to determine relative Mg absorption from the vegetables. Exchangeability was 90% or higher from all meals tested. Relative Mg absorption was highest from collards and least from the standard test meal. Net absorption values ranged from 40 to 60%.

  14. Acting Globally: Potential Carbon Emissions Mitigation Impacts from an International Standards and Labelling Program

    SciTech Connect (OSTI)

    McNeil, Michael A; Letschert, Virginie E.; de la Rue du Can, Stephane; Egan, Christine

    2009-05-29

    This paper presents an analysis of the potential impacts of an international initiative designed to support and promote the development and implementation of appliances standards and labelling programs throughout the world. As part of previous research efforts, LBNL developed the Bottom Up Energy Analysis System (BUENAS), an analysis framework that estimates impact potentials of energy efficiency policies on a global scale. In this paper, we apply this framework to an initiative that would result in the successful implementation of programs focused on high priority regions and product types, thus evaluating the potential impacts of such an initiative in terms of electricity savings and carbon mitigation in 2030. In order to model the likely parameters of such a program, we limit impacts to a five year period starting in 2009, but assume that the first 5 years of a program will result in implementation of 'best practice' minimum efficiency performance standards by 2014. The 'high priority' regions considered are: Brazil, China, the European Union,India, Mexico and the United States. The products considered are: refrigerators, air conditioners, lighting (both fluorescent and incandescent), standby power (for consumer electronics) and televisions in the residential sector, and air conditioning and lighting in commercial buildings. In 2020, these regions and enduses account for about 37percent of global residential electricity and 29percent of electricity in commercial buildings. We find that 850Mt of CO2 could be saved in buildings by 2030 compared to the baseline forecast.

  15. Nanoparticle-based immunosensor with apoferritin templated metallic phosphate label for quantification of phosphorylated acetylcholinesterase

    SciTech Connect (OSTI)

    Du, Dan; Chen, Aiqiong; Xie, Yunying; Zhang, Aidong; Lin, Yuehe

    2011-05-15

    A new sandwich-like electrochemical immunosensor has been developed for quantification of organophosphorylated acetylcholinesterase (OP-AChE), an exposure biomarker of organophosphate pesticides and nerve agents. Zirconia nanoparticles (ZrO2 NPs) were anchored on a screen printed electrode (SPE) to preferably capture OP-AChE adducts by metal chelation with phospho-moieties, which was selectively recognized by lead phosphate-apoferritin labeled anti-AChE antibody (LPA-anti-AChE). The sandwich-like immunoreactions were performed among ZrO2 NPs, OP-AChE and LPA-anti-AChE to form ZrO2/OP-AChE/LPA-anti-AChE complex and the released lead ions were detected on a disposable SPE. The binding affinity was investigated by both square wave voltammetry (SWV) and quartz crystal microbalance (QCM) measurements. The proposed immunosensor yielded a linear response current over a broad OP-AChE concentrations range from 0.05 nM to 10 nM, with detection limit of 0.02 nM, which has enough sensitivity for monitoring of low-dose exposure to OPs. This method avoids the drawback of unavailability of commercial OP-specific antibody as well as amplifies detection signal by using apoferritin encoded metallic phosphate nanoparticle tags. This nanoparticle-based immunosensor offers a new method for rapid, sensitive, selective and inexpensive quantification of phosphorylated adducts for monitoring of OP pesticides and nerve agents exposures.

  16. Validation of Innovative Exploration Technologies for Newberry Volcano: Map showing location of wells permitted, drilled and seismic test 2012

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Jaffe, Todd

    2012-01-01

    Innovative Exploration Technologies for Newberry Volcano: Map showing location of wells permitted, drilled & seismic test, 2012

  17. Validation of Innovative Exploration Technologies for Newberry Volcano: Map showing location of wells permitted, drilled and seismic test 2012

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Jaffe, Todd

    Innovative Exploration Technologies for Newberry Volcano: Map showing location of wells permitted, drilled & seismic test, 2012

  18. Note on gravitational baryogenesis

    SciTech Connect (OSTI)

    Sadjadi, H. Mohseni

    2007-12-15

    The coupling between Ricci scalar curvature and the baryon number current dynamically breaks CPT in an expanding universe and leads to baryon asymmetry. We study the effect of time dependence of the equation of state parameter of the Friedmann-Robertson-Walker universe on this asymmetry.

  19. Appendix A Explanatory Notes

    U.S. Department of Energy (DOE) all webpages (Extended Search)

    September 2016 98 U.S. Energy Information Administration | Natural Gas Monthly Dakota, Ohio, Pennsylvania, Utah, and West Virginia) were added to the EIA-914 data collection and ...

  20. ALARA notes, Number 8

    SciTech Connect (OSTI)

    Khan, T.A.; Baum, J.W.; Beckman, M.C.

    1993-10-01

    This document contains information dealing with the lessons learned from the experience of nuclear plants. In this issue the authors tried to avoid the `tyranny` of numbers and concentrated on the main lessons learned. Topics include: filtration devices for air pollution abatement, crack repair and inspection, and remote handling equipment.