National Library of Energy BETA

Sample records for mechanical problems repairs

  1. Mechanism of DNA interstrand cross-link processing by repair...

    Office of Scientific and Technical Information (OSTI)

    SciTech Connect Search Results Journal Article: Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1 Citation Details In-Document Search Title: Mechanism of ...

  2. Effect of multiple repairs in girth welds of pipelines on the mechanical properties

    SciTech Connect

    Vega, O.E.; Hallen, J.M.; Villagomez, A.

    2008-10-15

    This work presents the results of multiple weld repairs in the same area in seamless API X-52 microalloyed steel pipe. Four conditions of shielded metal arc welding repairs and one as-welded specimen of the girth weld were characterized to determine changes in the microstructure, grain size in the heat affected zone, and to evaluate their effect on the mechanical properties of the weld joints. The mechanical properties by means of tension tests, Charpy-V impact resistance and Vickers hardness of the welds were analyzed. The results indicate that significant changes are not generated in the microstructural constituents of the heat affected zone. Grain growth in the heat affected zone at the specimen mid-thickness with the number of repairs was observed. Tensile strength of the weld joints meets the requirement of the API 1104 standard even after the fourth weld repair. Significant reduction in Charpy-V impact resistance with the number of weld repairs was found when the notch location was in the intersection of the fusion line with the specimen mid-thickness. A significant increase in the Vickers hardness of the heat affected zone occurred after the first repair and a gradual decrease in the Vickers hardness occurred as the number of repairs increases.

  3. Quantum mechanics problems in observer's mathematics

    SciTech Connect

    Khots, Boris; Khots, Dmitriy

    2012-11-06

    This work considers the ontology, guiding equation, Schrodinger's equation, relation to the Born Rule, the conditional wave function of a subsystem in a setting of arithmetic, algebra and topology provided by Observer's Mathematics (see www.mathrelativity.com). Observer's Mathematics creates new arithmetic, algebra, geometry, topology, analysis and logic which do not contain the concept of continuum, but locally coincide with the standard fields. Certain results and communications pertaining to solutions of these problems are provided. In particular, we prove the following theorems: Theorem I (Two-slit interference). Let {Psi}{sub 1} be a wave from slit 1, {Psi}{sub 2} - from slit 2, and {Psi} = {Psi}{sub 1}+{Psi}{sub 2}. Then the probability of {Psi} being a wave equals to 0.5. Theorem II (k-bodies solution). For W{sub n} from m-observer point of view with m>log{sub 10}((2 Multiplication-Sign 10{sup 2n}-1){sup 2k}+1), the probability of standard expression of Hamiltonian variation is less than 1 and depends on n,m,k.

  4. INTERNAL REPAIR OF PIPELINES

    SciTech Connect

    Bill Bruce; Nancy Porter; George Ritter; Matt Boring; Mark Lozev; Ian Harris; Bill Mohr; Dennis Harwig; Robin Gordon; Chris Neary; Mike Sullivan

    2005-07-20

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without

  5. INTERNAL REPAIR OF PIPELINES

    SciTech Connect

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-12-31

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without

  6. INTERNAL REPAIR OF PIPELINES

    SciTech Connect

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-08-17

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners

  7. Evaluation and Repair of Primary Water Stress Corrosion Cracking in Alloy 600/182 Control Rod Drive Mechanism Nozzles

    SciTech Connect

    Frye, Charles R.; Arey, Melvin L. Jr.; Robinson, Michael R.; Whitaker, David E.

    2002-07-01

    In February 2001, a routine visual inspection of the reactor vessel head of Oconee Nuclear Station Unit 3 identified boric acid crystals at nine of sixty-nine locations where control rod drive mechanism housings (CRDM nozzles) penetrate the head. The boric acid deposits resulted from primary coolant leaking from cracks in the nozzle attachment weld and from through-thickness cracks in the nozzle wall. A general overview of the inspection and repair process is presented and results of the metallurgical analysis are discussed in more detail. The analysis confirmed that primary water stress corrosion cracking (PWSCC) is the mechanism of failure of both the Alloy 182 weld filler material and the alloy 600 wrought base material. (authors)

  8. Repair of hydroprocessing reactors

    SciTech Connect

    Niccolls, E.H.; Imgram, A.G.; Bagdasarian, A.J.

    1995-12-01

    In this paper the authors very briefly review the types of damage observed and repairs performed in hydroprocessing reactors. The authors will summarize the fundamental damage mechanisms, and where in the reactors they have needed to make repairs over the years. The era from the 1960`s through about 1990 will be briefly discussed. They describe in more detail repairs undertaken in the 1990`s. Finally, they will note important technical issues their industry faces regarding repairs, and the long term reliable operation of these vessels.

  9. Low Dose Radiation-Induced Genome and Epigenome Instability Symposium and Epigenetic Mechanisms, DNA Repair, and Chromatin Symposium at the EMS 2008 Annual Meeting - October 2008

    SciTech Connect

    Morgan, William F.; Kovalchuk, Olga; Dolinoy, Dana C.; Dubrova, Yuri E.; Coleman, Matthew A.; Schär, Primo; Pogribny, Igor; Hendzel, Michael

    2010-02-19

    The Low Dose Radiation Symposium thoughtfully addressed ionizing radiation non-mutational but transmissable alterations in surviving cells. Deregulation of epigenetic processes has been strongly implicated in carcinogenesis, and there is increasing realization that a significant fraction of non-targeted and adaptive mechanisms in response to ionizing radiation are likely to be epigenetic in nature. Much remains to be learned about how chromatin and epigenetic regulators affect responses to low doses of radiation, and how low dose radiation impacts other epigenetic processes. The Epigenetic Mechanisms Symposium focused on on epigenetic mechanisms and their interplay with DNA repair and chromatin changes. Addressing the fact that the most well understood mediators of epigenetic regulation are histone modifications and DNA methylation. Low levels of radiation can lead to changes in the methylation status of certain gene promoters and the expression of DNA methyltransferases, However, epigenetic regulation can also involve changes in higher order chromosome structure.

  10. Problem

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    2 Problem Scarcity of clean water leads to disease, death and often international tension. In many parts of the world, access to potable water is limited. The clean water supply...

  11. INTERNAL REPAIR OF PIPELINES

    SciTech Connect

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; Nancy Porter; Mike Sullivan; Chris Neary

    2004-04-12

    solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) Pipe diameter sizes range from 50.8 mm (2 in.) through 1,219.2 mm (48 in.). The most common size range for 80% to 90% of operators surveyed is 508 mm to 762 mm (20 in. to 30 in.), with 95% using 558.8 mm (22 in.) pipe. An evaluation of potential repair methods clearly indicates that the project should continue to focus on the development of a repair process involving the use of GMAW welding and on the development of a repair process involving the use of fiber-reinforced composite liners.

  12. Haier Repair Confusion Resolved | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Haier Repair Confusion Resolved Haier Repair Confusion Resolved April 26, 2010 - 12:28pm Addthis On January 7, 2010, DOE entered into a Consent Decree with Haier America regarding a problem with four models of Haier freezers that resulted in those freezers not achieving their advertised energy efficiency. DOE recently became aware that some consumers eligible for repairs were incorrectly told that they were not eligible. Haier has resolved the problem, and consumers are encouraged to contact

  13. Turbine repair process, repaired coating, and repaired turbine component

    SciTech Connect

    Das, Rupak; Delvaux, John McConnell; Garcia-Crespo, Andres Jose

    2015-11-03

    A turbine repair process, a repaired coating, and a repaired turbine component are disclosed. The turbine repair process includes providing a turbine component having a higher-pressure region and a lower-pressure region, introducing particles into the higher-pressure region, and at least partially repairing an opening between the higher-pressure region and the lower-pressure region with at least one of the particles to form a repaired turbine component. The repaired coating includes a silicon material, a ceramic matrix composite material, and a repaired region having the silicon material deposited on and surrounded by the ceramic matrix composite material. The repaired turbine component a ceramic matrix composite layer and a repaired region having silicon material deposited on and surrounded by the ceramic matrix composite material.

  14. Final report [DNA Repair and Mutagenesis - 1999

    SciTech Connect

    Walker, Graham C.

    2001-05-30

    The meeting, titled ''DNA Repair and Mutagenesis: Mechanism, Control, and Biological Consequences'', was designed to bring together the various sub-disciplines that collectively comprise the field of DNA Repair and Mutagenesis. The keynote address was titled ''Mutability Doth Play Her Cruel Sports to Many Men's Decay: Variations on the Theme of Translesion Synthesis.'' Sessions were held on the following themes: Excision repair of DNA damage; Transcription and DNA excision repair; UmuC/DinB/Rev1/Rad30 superfamily of DNA polymerases; Cellular responses to DNA damage, checkpoints, and damage tolerance; Repair of mismatched bases, mutation; Genome-instability, and hypermutation; Repair of strand breaks; Replicational fidelity, and Late-breaking developments; Repair and mutation in challenging environments; and Defects in DNA repair: consequences for human disease and aging.

  15. Aircraft Propeller Hub Repair

    SciTech Connect

    Muth, Thomas R.; Peter, William H.

    2015-02-13

    The team performed a literature review, conducted residual stress measurements, performed failure analysis, and demonstrated a solid state additive manufacturing repair technique on samples removed from a scrapped propeller hub. The team evaluated multiple options for hub repair that included existing metal buildup technologies that the Federal Aviation Administration (FAA) has already embraced, such as cold spray, high velocity oxy-fuel deposition (HVOF), and plasma spray. In addition the team helped Piedmont Propulsion Systems, LLC (PPS) evaluate three potential solutions that could be deployed at different stages in the life cycle of aluminum alloy hubs, in addition to the conventional spray coating method for repair. For new hubs, a machining practice to prevent fretting with the steel drive shaft was recommended. For hubs that were refurbished with some material remaining above the minimal material condition (MMC), a silver interface applied by an electromagnetic pulse additive manufacturing method was recommended. For hubs that were at or below the MMC, a solid state additive manufacturing technique using ultrasonic welding (UW) of thin layers of 7075 aluminum to the hub interface was recommended. A cladding demonstration using the UW technique achieved mechanical bonding of the layers showing promise as a viable repair method.

  16. Motor Repair Tech Brief

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Motor Repair Tech Brief u Why do motors fail? u When should you repair instead of replace? u How can reliability and efficiency be assured in a repair? This Tech Brief applies to: Random Wound Induction Motors Designs A-E Acknowledgements The following series of Repair Documents-The Service Center Evaluation Guide, Selected Bibliography on Electric Motor Repair, Model Repair Specifications for Low Voltage Motors, and Motor Repair Tech Brief- were produced by the U.S. Department of Energy's

  17. Coupled discrete element and finite volume solution of two classical soil mechanics problems

    SciTech Connect

    Chen, Feng; Drumm, Eric; Guiochon, Georges A

    2011-01-01

    One dimensional solutions for the classic critical upward seepage gradient/quick condition and the time rate of consolidation problems are obtained using coupled routines for the finite volume method (FVM) and discrete element method (DEM), and the results compared with the analytical solutions. The two phase flow in a system composed of fluid and solid is simulated with the fluid phase modeled by solving the averaged Navier-Stokes equation using the FVM and the solid phase is modeled using the DEM. A framework is described for the coupling of two open source computer codes: YADE-OpenDEM for the discrete element method and OpenFOAM for the computational fluid dynamics. The particle-fluid interaction is quantified using a semi-empirical relationship proposed by Ergun [12]. The two classical verification problems are used to explore issues encountered when using coupled flow DEM codes, namely, the appropriate time step size for both the fluid and mechanical solution processes, the choice of the viscous damping coefficient, and the number of solid particles per finite fluid volume.

  18. INTERNAL REPAIR OF PIPELINES

    SciTech Connect

    Robin Gordon; Bill Bruce; Nancy Porter; Mike Sullivan; Chris Neary

    2003-05-01

    The two broad categories of deposited weld metal repair and fiber-reinforced composite repair technologies were reviewed for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Preliminary test programs were developed for both deposited weld metal repairs and for fiber-reinforced composite repair. To date, all of the experimental work pertaining to the evaluation of potential repair methods has focused on fiber-reinforced composite repairs. Hydrostatic testing was also conducted on four pipeline sections with simulated corrosion damage: two with composite liners and two without.

  19. Reputation mechanism: From resolution for truthful online auctions to the model of optimal one-gambler problem

    SciTech Connect

    Bradonjic, Milan

    2009-01-01

    In this paper we study reputation mechanisms, and show how the notion of reputation can help us in building truthful online auction mechanisms. From the mechanism design prospective, we derive the conditions on and design a truthful online auction mechanism. Moreover, in the case when some agents may lay or cannot have the real knowledge about the other agents reputations, we derive the resolution of the auction, such that the mechanism is truthful. Consequently, we move forward to the optimal one-gambler/one-seller problem, and explain how that problem is refinement of the previously discussed online auction design in the presence of reputation mechanism. In the setting of the optimal one-gambler problem, we naturally rise and solve the specific question: What is an agent's optimal strategy, in order to maximize his revenue? We would like to stress that our analysis goes beyond the scope, which game theory usually discusses under the notion of reputation. We model one-player games, by introducing a new parameter (reputation), which helps us in predicting the agent's behavior, in real-world situations, such as, behavior of a gambler, real-estate dealer, etc.

  20. Rapid road repair vehicle

    DOEpatents

    Mara, Leo M.

    1998-01-01

    Disclosed is a rapid road repair vehicle capable of moving over a surface to be repaired at near normal posted traffic speeds to scan for and find an the high rate of speed, imperfections in the pavement surface, prepare the surface imperfection for repair by air pressure and vacuum cleaning, applying a correct amount of the correct patching material to effect the repair, smooth the resulting repaired surface, and catalog the location and quality of the repairs for maintenance records of the road surface. The rapid road repair vehicle can repair surface imperfections at lower cost, improved quality, at a higher rate of speed than was was heretofor possible, with significantly reduced exposure to safety and health hazards associated with this kind of road repair activities in the past.

  1. Rapid road repair vehicle

    DOEpatents

    Mara, L.M.

    1998-05-05

    Disclosed is a rapid road repair vehicle capable of moving over a surface to be repaired at near normal posted traffic speeds to scan for and find at the high rate of speed, imperfections in the pavement surface, prepare the surface imperfection for repair by air pressure and vacuum cleaning, applying a correct amount of the correct patching material to effect the repair, smooth the resulting repaired surface, and catalog the location and quality of the repairs for maintenance records of the road surface. The rapid road repair vehicle can repair surface imperfections at lower cost, improved quality, at a higher rate of speed than was not heretofor possible, with significantly reduced exposure to safety and health hazards associated with this kind of road repair activities in the past. 2 figs.

  2. Class of model problems in three-body quantum mechanics that admit exact solutions

    SciTech Connect

    Takibayev, N. Zh.

    2008-03-15

    An approach to solving scattering problems in three-body systems for cases where the mass of one of the particles is extremely small in relation to the masses of the other two particles and where the pair potentials of interaction between the particles involved are separable is developed. Exact analytic solutions to such model problems are found for the scattering of a light particle on two fixed centers and on two interacting heavy particles. It is shown that new resonances and a dynamical resonance enhancement may appear in a three-body system.

  3. Solution of large nonlinear quasistatic structural mechanics problems on distributed-memory multiprocessor computers

    SciTech Connect

    Blanford, M.

    1997-12-31

    Most commercially-available quasistatic finite element programs assemble element stiffnesses into a global stiffness matrix, then use a direct linear equation solver to obtain nodal displacements. However, for large problems (greater than a few hundred thousand degrees of freedom), the memory size and computation time required for this approach becomes prohibitive. Moreover, direct solution does not lend itself to the parallel processing needed for today`s multiprocessor systems. This talk gives an overview of the iterative solution strategy of JAS3D, the nonlinear large-deformation quasistatic finite element program. Because its architecture is derived from an explicit transient-dynamics code, it does not ever assemble a global stiffness matrix. The author describes the approach he used to implement the solver on multiprocessor computers, and shows examples of problems run on hundreds of processors and more than a million degrees of freedom. Finally, he describes some of the work he is presently doing to address the challenges of iterative convergence for ill-conditioned problems.

  4. Philosophy of Mind and the Problem of FreeWill in the Light of Quantum Mechanics.

    SciTech Connect

    Stapp, Henry; Stapp, Henry P

    2008-04-01

    Arguments pertaining to the mind-brain connection and to the physical effectiveness of our conscious choices have been presented in two recent books, one by John Searle, the other by Jaegwon Kim. These arguments are examined, and it is argued that the difficulties encountered arise from a defective understanding and application of a pertinent part of contemporary science, namely quantum mechanics.

  5. Service and Repair Work

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Jupiter Laser Facility, please contact Sean Holte (2-3905, pager 05312). Notify Brent Stuart and Beth Mariotti whenever you bring a visitor to inspect, service, or repair...

  6. Repairable chip bonding/interconnect process

    DOEpatents

    Bernhardt, A.F.; Contolini, R.J.; Malba, V.; Riddle, R.A.

    1997-08-05

    A repairable, chip-to-board interconnect process which addresses cost and testability issues in the multi-chip modules is disclosed. This process can be carried out using a chip-on-sacrificial-substrate technique, involving laser processing. This process avoids the curing/solvent evolution problems encountered in prior approaches, as well is resolving prior plating problems and the requirements for fillets. For repairable high speed chip-to-board connection, transmission lines can be formed on the sides of the chip from chip bond pads, ending in a gull wing at the bottom of the chip for subsequent solder. 10 figs.

  7. Repairable chip bonding/interconnect process

    DOEpatents

    Bernhardt, Anthony F.; Contolini, Robert J.; Malba, Vincent; Riddle, Robert A.

    1997-01-01

    A repairable, chip-to-board interconnect process which addresses cost and testability issues in the multi-chip modules. This process can be carried out using a chip-on-sacrificial-substrate technique, involving laser processing. This process avoids the curing/solvent evolution problems encountered in prior approaches, as well is resolving prior plating problems and the requirements for fillets. For repairable high speed chip-to-board connection, transmission lines can be formed on the sides of the chip from chip bond pads, ending in a gull wing at the bottom of the chip for subsequent solder.

  8. Development of bonded composite doublers for the repair of oil recovery equipment.

    SciTech Connect

    Roach, David W.; Rackow, Kirk A.

    2005-06-01

    An unavoidable by-product of a metallic structure's use is the appearance of crack and corrosion flaws. Economic barriers to the replacement of these structures have created an aging infrastructure and placed even greater demands on efficient and safe repair methods. In the past decade, an advanced composite repair technology has made great strides in commercial aviation use. Extensive testing and analysis, through joint programs between the Sandia Labs FAA Airworthiness Assurance Center and the aviation industry, have proven that composite materials can be used to repair damaged aluminum structure. Successful pilot programs have produced flight performance history to establish the durability of bonded composite patches as a permanent repair on commercial aircraft structures. With this foundation in place, this effort is adapting bonded composite repair technology to civil structures. The use of bonded composite doublers has the potential to correct the difficulties associated with current repair techniques and the ability to be applied where there are no rehabilitation options. It promises to be cost-effective with minimal disruption to the users of the structure. This report concludes a study into the application of composite patches on thick steel structures typically used in mining operations. Extreme fatigue, temperature, erosive, and corrosive environments induce an array of equipment damage. The current weld repair techniques for these structures provide a fatigue life that is inferior to that of the original plate. Subsequent cracking must be revisited on a regular basis. The use of composite doublers, which do not have brittle fracture problems such as those inherent in welds, can help extend the structure's fatigue life and reduce the equipment downtime. Two of the main issues for adapting aircraft composite repairs to civil applications are developing an installation technique for carbon steel and accommodating large repairs on extremely thick structures

  9. EUVL Mask Blank Repair

    SciTech Connect

    Barty, A; Mirkarimi, P; Stearns, D G; Sweeney, D; Chapman, H N; Clift, M; Hector, S; Yi, M

    2002-05-22

    EUV mask blanks are fabricated by depositing a reflective Mo/Si multilayer film onto super-polished substrates. Small defects in this thin film coating can significantly alter the reflected field and introduce defects in the printed image. Ideally one would want to produce defect-free mask blanks; however, this may be very difficult to achieve in practice. One practical way to increase the yield of mask blanks is to effectively repair multilayer defects, and to this effect they present two complementary defect repair strategies for use on multilayer-coated EUVL mask blanks. A defect is any area on the mask which causes unwanted variations in EUV dose in the aerial image obtained in a printing tool, and defect repair is correspondingly defined as any strategy that renders a defect unprintable during exposure. The term defect mitigation can be adopted to describe any strategy which renders a critical defect non-critical when printed, and in this regard a non-critical defect is one that does not adversely affect device function. Defects in the patterned absorber layer consist of regions where metal, typically chrome, is unintentionally added or removed from the pattern leading to errors in the reflected field. There currently exists a mature technology based on ion beam milling and ion beam assisted deposition for repairing defects in the absorber layer of transmission lithography masks, and it is reasonable to expect that this technology will be extended to the repair of absorber defects in EUVL masks. However, techniques designed for the repair of absorber layers can not be directly applied to the repair of defects in the mask blank, and in particular the multilayer film. In this paper they present for the first time a new technique for the repair of amplitude defects as well as recent results on the repair of phase defects.

  10. Rapid road repair vehicle

    DOEpatents

    Mara, Leo M.

    1999-01-01

    Disclosed are improvments to a rapid road repair vehicle comprising an improved cleaning device arrangement, two dispensing arrays for filling defects more rapidly and efficiently, an array of pre-heaters to heat the road way surface in order to help the repair material better bond to the repaired surface, a means for detecting, measuring, and computing the number, location and volume of each of the detected surface imperfection, and a computer means schema for controlling the operation of the plurality of vehicle subsystems. The improved vehicle is, therefore, better able to perform its intended function of filling surface imperfections while moving over those surfaces at near normal traffic speeds.

  11. Inspect and Repair Steam Traps

    Energy.gov [DOE]

    This tip sheet on inspecting and repairing steam traps provides how-to advice for improving industrial steam systems using low-cost, proven practices and technologies.

  12. Open Problems, Solved Problems !

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Problems, Solved Problems and Non-Problems in DOE's Big Data Kathy Y elick Professor o f E lectrical E ngineering a nd C omputer S ciences University o f C alifornia a t B...

  13. The extended Bloch representation of quantum mechanics and the hidden-measurement solution to the measurement problem

    SciTech Connect

    Aerts, Diederik; Sassoli de Bianchi, Massimiliano

    2014-12-15

    A generalized Bloch sphere, in which the states of a quantum entity of arbitrary dimension are geometrically represented, is investigated and further extended, to also incorporate the measurements. This extended representation constitutes a general solution to the measurement problem, inasmuch it allows to derive the Born rule as an average over hidden-variables, describing not the state of the quantum entity, but its interaction with the measuring system. According to this modelization, a quantum measurement is to be understood, in general, as a tripartite process, formed by an initial deterministic decoherence-like process, a subsequent indeterministic collapse-like process, and a final deterministic purification-like process. We also show that quantum probabilities can be generally interpreted as the probabilities of a first-order non-classical theory, describing situations of maximal lack of knowledge regarding the process of actualization of potential interactions, during a measurement. - Highlights: • An extended Bloch representation of quantum measurements is given. • Quantum measurements are explained in terms of hidden-measurement interactions. • Quantum measurements are explained as tripartite processes. • The Born rule results from a universal average, over all possible measurement processes.

  14. Inspect and Repair Steam Traps

    SciTech Connect

    Not Available

    2006-01-01

    This revised ITP tip sheet on inspecting and repairing steam traps provide how-to advice for improving industrial steam systems using low-cost, proven practices and technologies.

  15. Motor Repair Tech Brief | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Repair Tech Brief Motor Repair Tech Brief This Tech Brief answers: Why do motors fail? When should you repair instead of replace? And how can reliability and efficiency be assured in a repair? Motor Repair Tech Brief (March 2000) (941.96 KB) More Documents & Publications Extend the Operating Life of Your Motor Service Center Evaluation Guide Premium Efficiency Motor Selection and Application Guide - A Handbook for Industry

  16. Selected Bibliography on Electric Motor Repair

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Selected Bibliography on Electric Motor Repair Acknowledgements The following series of Repair Documents-The Service Center Evaluation Guide, Selected Bibliography on Electric Motor Repair, Model Repair Specifications for Low Voltage Motors, and Motor Repair Tech Brief- were produced by the U.S. Department of Energy's Office of Industrial Technologies (OIT) with input from trade associations, consulting companies, manufacturers, non-profit corporations, and others. OIT would like to thank the

  17. Thermosetting Polymer-Matrix Composites for Strucutral Repair Applications

    SciTech Connect

    William Kirby Goertzen

    2007-12-01

    Several classes of thermosetting polymer matrix composites were evaluated for use in structural repair applications. Initial work involved the characterization and evaluation of woven carbon fiber/epoxy matrix composites for structural pipeline repair. Cyanate ester resins were evaluated as a replacement for epoxy in composites for high-temperature pipe repair applications, and as the basis for adhesives for resin infusion repair of high-temperature composite materials. Carbon fiber/cyanate ester matrix composites and fumed silica/cyanate ester nanocomposites were evaluated for their thermal, mechanical, viscoelastic, and rheological properties as they relate to their structure, chemistry, and processing characteristics. The bisphenol E cyanate ester under investigation possesses a high glass transition temperature, excellent mechanical properties, and unique ambient temperature processability. The incorporate of fumed silica served to enhance the mechanical and rheological properties of the polymer and reduce thermal expansion without sacrificing glass transition or drastically altering curing kinetics. Characterization of the composites included dynamic mechanical analysis, thermomechanical analysis, differential scanning calorimetry, thermogravimetric analysis, rheological and rheokinetic evaluation, and transmission electron microscopy.

  18. Selected Bibliography on Electric Motor Repair | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Selected Bibliography on Electric Motor Repair Selected Bibliography on Electric Motor Repair The following series of repair documents related to electric motors were produced by...

  19. Communication: Practical and rigorous reduction of the many-electron quantum mechanical Coulomb problem to O(N{sup 2/3}) storage

    SciTech Connect

    Pederson, Mark R.

    2015-04-14

    It is tacitly accepted that, for practical basis sets consisting of N functions, solution of the two-electron Coulomb problem in quantum mechanics requires storage of O(N{sup 4}) integrals in the small N limit. For localized functions, in the large N limit, or for planewaves, due to closure, the storage can be reduced to O(N{sup 2}) integrals. Here, it is shown that the storage can be further reduced to O(N{sup 2/3}) for separable basis functions. A practical algorithm, that uses standard one-dimensional Gaussian-quadrature sums, is demonstrated. The resulting algorithm allows for the simultaneous storage, or fast reconstruction, of any two-electron Coulomb integral required for a many-electron calculation on processors with limited memory and disk space. For example, for calculations involving a basis of 9171 planewaves, the memory required to effectively store all Coulomb integrals decreases from 2.8 Gbytes to less than 2.4 Mbytes.

  20. Injection repair of carbon fiber/bismaleimide composite panels with bisphenol E cyanate ester resin

    SciTech Connect

    Thunga, Mahendra; Bauer, Amy; Obusek, Kristine; Meilunas, Ray; Akinc, Mufit; Kessler, Michael R

    2014-08-01

    Resin injection of bisphenol E cyanate ester, a low viscosity resin that cures into a high temperature thermoset polymer, is investigated as a reliable repair method to restore strength and stiffness in delaminated carbon fiber/bismaleimide composites used in aircraft panels. The influence of temperature on the viscosity of the uncured resin was measured to optimize the injection conditions for high resin infiltration into the delaminations. The repair efficiency of the resin was evaluated by varying the panel thickness and the method by which the delamination damage was created in the composite specimens. Ultrasonic scanning (C-scan), flash thermography images, and cross-section analysis of repaired panels revealed excellent resin infiltration into the damaged region. Evaluation of mechanical repair efficiency using both bending stiffness and in-plain compressive strength of the composite panels as the repair metrics showed values exceeding 100%.

  1. Fabrication Flaw Density and Distribution In Repairs to Reactor Pressure Vessel and Piping Welds

    SciTech Connect

    GJ Schuster, FA Simonen, SR Doctor

    2008-04-01

    The Pacific Northwest National Laboratory is developing a generalized fabrication flaw distribution for the population of nuclear reactor pressure vessels and for piping welds in U.S. operating reactors. The purpose of the generalized flaw distribution is to predict component-specific flaw densities. The estimates of fabrication flaws are intended for use in fracture mechanics structural integrity assessments. Structural integrity assessments, such as estimating the frequency of loss-of-coolant accidents, are performed by computer codes that require, as input, accurate estimates of flaw densities. Welds from four different reactor pressure vessels and a collection of archived pipes have been studied to develop empirical estimates of fabrication flaw densities. This report describes the fabrication flaw distribution and characterization in the repair weld metal of vessels and piping. This work indicates that large flaws occur in these repairs. These results show that repair flaws are complex in composition and sometimes include cracks on the ends of the repair cavities. Parametric analysis using an exponential fit is performed on the data. The relevance of construction records is established for describing fabrication processes and product forms. An analysis of these records shows there was a significant change in repair frequency over the years when these components were fabricated. A description of repair flaw morphology is provided with a discussion of fracture mechanics significance. Fabrication flaws in repairs are characterized using optimized-access, high-sensitivity nondestructive ultrasonic testing. Flaw characterizations are then validated by other nondestructive evaluation techniques and complemented by destructive testing.

  2. Assessment of HYGAS mechanical equipment

    SciTech Connect

    Albrecht, P.R.; Kramberger, F.E.; Recupero, R.M.; Verden, M.L.; Rees, K.

    1980-10-01

    The HYGAS process, which converts coal to substitute natural gas, is being developed by the Institute of Gas Technology (IGT) using an 80 ton per day pilot plant located in Chicago, Illinois. Plant design started in 1967 and testing began in October 1971. Since then, 18,000 tons of both Eastern and Western coal have been gasified. Assessment of the mechanical equipment was made by Mechanical Technology Incorporated (MTI) in collaboration with a DOE on-site representative and a representative from IGT, the operating contractor. Data for the assessment were obtained by reviewing all available maintenance records, by interviewing key personnel from maintenance and operations, and by observing repairs and maintenance procedures where possible. While operating the plant, a variety of equipment problems were addressed, many of which are generic to HYGAS as well as other coal conversion processes. Some problems were solved completely while others were solved to suit the limited needs of the pilot plant. Accordingly, the emphasis of this study is on the degree of success in dealing with equipment failures, the unresolved problems and the implication to future coal conversion plants.

  3. Assessment of Synthane mechanical equipment

    SciTech Connect

    McCabe, J.T.; Kramberger, F.E.; Hao, B.R.; Dubis, D.; Carson, S.E.

    1980-05-01

    The objective of this report is to provide a base-line condition assessment of the key equipment of the synthane process pilot plant based on a historical review of performance, vibration monitoring and a preliminary systems analysis. The historical review of equipment performance was conducted by reviewing all available maintenance and repair records filed at the Synthane pilot plant, interviewing key Maintenance and Operations personnel and observing repair and maintenance procedures where possible. Field vibration measurements of all major rotating components were made periodically to detect current and approaching equipment problems. An overview of the influence of mechanical equipment on plant performance was provided by a systems analysis. The process equipment was categorized according to subsystem function, design source and application to future-generation plants. The analysis was conducted by examining data from the plant operating log to clarify the causes and implications of important equipment-related events. The results of this base line condition assessment of the key equipment at the Synthane pilot plant emphasize the need to expand the objectives of future pilot and demonstration plants and provide for the following recommendations: include equipment performance and reliability objectives as an integral part of the operational program; maintain an effective maintenance and repair data-collection system; conduct comprehensive equipment-failure analysis; establish structured corrective action procedures with high-level disposition; and conduct concurrent systems analysis and provide feedback to plant operations. The incorporation of these recommendations in future pilot and demonstration plants will yield major cost benefits in the operating phases of these programs and in future commercial plants.

  4. IN OTHER CATEGORIES; MACHINERY; MASS BALANCE; MECHANICAL VIBRATIONS...

    Office of Scientific and Technical Information (OSTI)

    world Bracher, B. 42 ENGINEERING NOT INCLUDED IN OTHER CATEGORIES; MACHINERY; MASS BALANCE; MECHANICAL VIBRATIONS; MAINTENANCE; REPAIR Field balancing can achieve significant...

  5. Distribution System Audits, Leak Detection, and Repair: Kirtland Air Force Base Leak Detection and Repair Program

    SciTech Connect

    2009-01-14

    Water Best Management Practice #3 Fact Seet: Outlines how a leak detection and repair program helped Kirtland Air Force Base perform distribution system audits, leak detection, and repair to conserve water site-wide.

  6. CDK1 enhances mitochondrial bioenergetics for radiation-induced DNA repair

    DOE PAGES [OSTI]

    Qin, Lili; Fan, Ming; Candas, Demet; Jiang, Guochun; Papadopoulos, Stelios; Tian, Lin; Woloschak, Gayle; Grdina, David J.; Li, Jian  Jian

    2015-12-06

    Nuclear DNA repair capacity is a critical determinant of cell fate under genotoxic stress conditions. DNA repair is a well-defined energy-consuming process. However, it is unclear how DNA repair is fueled and whether mitochondrial energy production contributes to nuclear DNA repair. Here, we report a dynamic enhancement of oxygen consumption and mitochondrial ATP generation in irradiated normal cells, paralleled with increased mitochondrial relocation of the cell-cycle kinase CDK1 and nuclear DNA repair. The basal and radiation-induced mitochondrial ATP generation is reduced significantly in cells harboring CDK1 phosphorylation-deficient mutant complex I subunits. Similarly, mitochondrial ATP generation and nuclear DNA repair aremore »also compromised severely in cells harboring mitochondrially targeted, kinase-deficient CDK1. These findings demonstrate a mechanism governing the communication between mitochondria and the nucleus by which CDK1 boosts mitochondrial bioenergetics to meet the increased cellular fuel demand for DNA repair and cell survival under genotoxic stress conditions.« less

  7. Internal pipe attachment mechanism

    DOEpatents

    Bast, R.M.; Chesnut, D.A.; Henning, C.D.; Lennon, J.P.; Pastrnak, J.W.; Smith, J.A.

    1994-12-13

    An attachment mechanism is described for repairing or extending fluid carrying pipes, casings, conduits, etc. utilizing one-way motion of spring tempered fingers to provide a mechanical connection between the attachment mechanism and the pipe. The spring tempered fingers flex to permit insertion into a pipe to a desired insertion depth. The mechanical connection is accomplished by reversing the insertion motion and the mechanical leverage in the fingers forces them outwardly against the inner wall of the pipe. A seal is generated by crushing a sealing assembly by the action of setting the mechanical connection. 6 figures.

  8. Internal pipe attachment mechanism

    DOEpatents

    Bast, Richard M.; Chesnut, Dwayne A.; Henning, Carl D.; Lennon, Joseph P.; Pastrnak, John W.; Smith, Joseph A.

    1994-01-01

    An attachment mechanism for repairing or extending fluid carrying pipes, casings, conduits, etc. utilizing one-way motion of spring tempered fingers to provide a mechanical connection between the attachment mechanism and the pipe. The spring tempered fingers flex to permit insertion into a pipe to a desired insertion depth. The mechanical connection is accomplished by reversing the insertion motion and the mechanical leverage in the fingers forces them outwardly against the inner wall of the pipe. A seal is generated by crushing a sealing assembly by the action of setting the mechanical connection.

  9. Unmanned deepwater-line repair system passes full-scale trials

    SciTech Connect

    Venzi, S.; Vienna, A. )

    1993-09-06

    The first ever full-scale tests of an unmanned, deepwater-pipeline repair system were successfully conducted last year off the coast of Italy. The Italian gas-transmission company SNAM tested a submersible automatic system (SAS) sealine repair system at a depth of 600 m. The modular SAS allows sealines to be repaired by installation of the Nuovo Pignone mechanical connector. The system's trials simulated complete repair intervention on the 20-in. Trans mediterranean pipeline and provided unprecedented experience to SNAM and to the other involved in this project. The paper discusses the origin of the idea for the SAS, the design of the system, construction and testing, the first sea trials, final deep sea trials, and future developments.

  10. Inducible error-prone repair in B. subtilis. Final report, September 1, 1979-June 30, 1981

    SciTech Connect

    Yasbin, R. E.

    1981-06-01

    The research performed under this contract has been concentrated on the relationship between inducible DNA repair systems, mutagenesis and the competent state in the gram positive bacterium Bacillus subtilis. The following results have been obtained from this research: (1) competent Bacillus subtilis cells have been developed into a sensitive tester system for carcinogens; (2) competent B. subtilis cells have an efficient excision-repair system, however, this system will not function on bacteriophage DNA taken into the cell via the process of transfection; (3) DNA polymerase III is essential in the mechanism of the process of W-reactivation; (4) B. subtilis strains cured of their defective prophages have been isolated and are now being developed for gene cloning systems; (5) protoplasts of B. subtilis have been shown capable of acquiring DNA repair enzymes (i.e., enzyme therapy); and (6) a plasmid was characterized which enhanced inducible error-prone repair in a gram positive organism.

  11. Known Problems

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Known Problems Known Problems No Open Issues There are currently no open issues with Euclid. Read the full post Subscribe via RSS Subscribe Browse by Date January 2016 Last edited: 2016-04-29 11:34:51

  12. Known Problems

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Problems Known Problems Viewing entries posted in 2001 There are no blog entries Subscribe via RSS Subscribe Browse by Date January 2016 Last edited: 2016-04-29 11:34:51

  13. INTERNAL REPAIR OF PIPELINES REVIEW & EVALUATION OF INTERNAL PIPELINE REPAIR TRIALS REPORT

    SciTech Connect

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-09-01

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is generally ineffective at restoring the pressure containing capabilities of pipelines. Failure pressure for pipe repaired with carbon fiber-reinforced composite liner was greater than that of the un-repaired pipe section with damage, indicating that this type of liner is effective at restoring the pressure containing capability of pipe. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. Development of a comprehensive test plan for this process is recommended for use in the next phase of this project.

  14. Solar Water Heating System Maintenance and Repair | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Water Heating System Maintenance and Repair Solar Water Heating System Maintenance and Repair Rooftop solar water heaters need regular maintenance to operate at peak efficiency. |...

  15. Leveraging Service Calls and Emergency Repairs for Energy Efficiency...

    Energy Saver

    Service Calls and Emergency Repairs for Energy Efficiency Marketing Leveraging Service Calls and Emergency Repairs for Energy Efficiency Marketing Better Buildings Residential ...

  16. Solar Water Heating System Maintenance and Repair | Department...

    Energy Saver

    Water Heating System Maintenance and Repair Solar Water Heating System Maintenance and Repair Rooftop solar water heaters need regular maintenance to operate at peak efficiency. | ...

  17. Significant accumulation of persistent organic pollutants and dysregulation in multiple DNA damage repair pathways in the electronic-waste-exposed populations

    SciTech Connect

    He, Xiaobo; Jing, Yaqing; Wang, Jianhai; Li, Keqiu; Yang, Qiaoyun; Zhao, Yuxia; Li, Ran; Ge, Jie; Qiu, Xinghua; Li, Guang

    2015-02-15

    Electronic waste (e-waste) has created a worldwide environmental and health problem, by generating a diverse group of hazardous compounds such as persistent organic pollutants (POPs). Our previous studies demonstrated that populations from e-waste exposed region have a significantly higher level of chromosomal aberrancy and incidence of DNA damage. In this study, we further demonstrated that various POPs persisted at a significantly higher concentration in the exposed group than those in the unexposed group. The level of reactive oxygen species and micronucleus rate were also significantly elevated in the exposed group. RNA sequencing analysis revealed 31 genes in DNA damage responses and repair pathways that were differentially expressed between the two groups (Log 2 ratio >1 or <−1). Our data demonstrated that both females and males of the exposed group have activated a series of DNA damage response genes; however many important DNA repair pathways have been dysregulated. Expressions of NEIL1/3 and RPA3, which are critical in initiating base pair and nucleotide excision repairs respectively, have been downregulated in both females and males of the exposed group. In contrast, expression of RNF8, an E3 ligase involved in an error prone non-homologous end joining repair for DNA double strand break, was upregulated in both genders of the exposed group. The other genes appeared to be differentially expressed only when the males or females of the two groups were compared respectively. Importantly, the expression of cell cycle regulatory gene CDC25A that has been implicated in multiple kinds of malignant transformation was significantly upregulated among the exposed males while downregulated among the exposed females. In conclusion, our studies have demonstrated significant correlations between e-waste disposing and POPs accumulation, DNA lesions and dysregulation of multiple DNA damage repair mechanisms in the residents of the e-waste exposed region. - Highlights:

  18. Developments advance subsea pipelaying, inspection, repair

    SciTech Connect

    1997-09-15

    Recent advances in laying, inspecting, and repairing pipelines are helping to cut both costs and time. A new dredging system that employs jets to clear a subsea trench for pipelay received trials off Belgium last spring. Also, within the last year, projects in the Middle East and North Sea employed technologies that promise to make inspecting the surface of a subsea pipeline in difficult terrain easier, less time consuming, and therefore less costly. Plus, subsea repair of damaged pipelines may take less time with a new ``stabbable`` pipe connector. The paper describes jet dredging, inspection advance, support software, the North Sea site, and pipeline repair.

  19. Formation and Repair of Tobacco Carcinogen-Derived Bulky DNA Adducts

    DOE PAGES [OSTI]

    Hang, Bo

    2010-01-01

    DNA adducts play a central role in chemical carcinogenesis. The analysis of formation and repair of smoking-related DNA adducts remains particularly challenging as both smokers and nonsmokers exposed to smoke are repetitively under attack from complex mixtures of carcinogens such as polycyclic aromatic hydrocarbons and N -nitrosamines. The bulky DNA adducts, which usually have complex structure, are particularly important because of their biological relevance. Several known cellular DNA repair pathways have been known to operate in human cells on specific types of bulky DNA adducts, for example, nucleotide excision repair, base excision repair, and direct reversal involving O 6more » -alkylguanine DNA alkyltransferase or AlkB homologs. Understanding the mechanisms of adduct formation and repair processes is critical for the assessment of cancer risk resulting from exposure to cigarette smoke, and ultimately for developing strategies of cancer prevention. This paper highlights the recent progress made in the areas concerning formation and repair of bulky DNA adducts in the context of tobacco carcinogen-associated genotoxic and carcinogenic effects.« less

  20. Laser engineered net shaping (LENS) for the repair and modification of NWC metal components.

    SciTech Connect

    Atwood, Clinton J.; Smugeresky, John E. (Sandia National Labs, Livermore,CA); Gill, David Dennis

    2006-11-01

    Laser Engineered Net Shaping{trademark} (LENS{reg_sign}) is a layer additive manufacturing process that creates fully dense metal components using a laser, metal powder, and a computer solid model. This process has previously been utilized in research settings to create metal components and new material alloys. The ''Qualification of LENS for the Repair and Modification of Metal NWC Components'' project team has completed a Technology Investment project to investigate the use of LENS for repair of high rigor components. The team submitted components from four NWC sites for repair or modification using the LENS process. These components were then evaluated for their compatibility to high rigor weapons applications. The repairs included hole filling, replacement of weld lips, addition of step joints, and repair of surface flaws and gouges. The parts were evaluated for mechanical properties, corrosion resistance, weldability, and hydrogen compatibility. This document is a record of the LENS processing of each of these component types and includes process parameters, build strategies, and lessons learned. Through this project, the LENS process was shown to successfully repair or modify metal NWC components.

  1. A Guide to AC Motor Repair and Replacement

    SciTech Connect

    2004-03-01

    This booklet provides helpful information for making informed repair or replace decisions for electric motors.

  2. Electronic Fabrication & Repair | The Ames Laboratory

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Electronic Fabrication & Repair The Electronics group provides custom design and fabrication of electronic equipment.. We convert ideas into custom-finished equipment in our shop using ORCAD Schematic Capture and PCB Layout software in conjunction with our PCB machine to make prototype circuit boards in-house. Our technicians also aid in automating and controlling research project instrumentation using Texas Instruments LabView. We repair all kinds of scientific and laboratory electronic and

  3. Fabrication Flaw Density and Distribution in the Repairs of Reactor Pressure Vessels

    SciTech Connect

    Schuster, George J.; Doctor, Steven R.; Simonen, Fredric A.

    2006-02-15

    The Pacific Northwest National Laboratory (PNNL) is developing a generalized flaw size and density distribution for the population of U.S. reactor pressure vessels (RPVs). The purpose of the generalized flaw distribution is to predict vessel specific flaw rates for use in probabilistic fracture mechanics calculations that estimate vessel failure probability. Considerable progress has been made on the construction of an engineering data base of fabrication flaws in U.S. nuclear RPVs. The fabrication processes and product forms used to construct U.S. RPVs are represented in the data base. A validation methodology has been developed for characterizing the flaws for size, shape, orientation, and composition. The relevance of construction records has been established for describing fabrication processes and product forms. The fabrication flaws were detected in material removed from cancelled nuclear power plants using high sensitivity nondestructive ultrasonic testing, and validated by other nondestructive evaluation (NDE) techniques, and complemented by destructive testing. This paper describes research that has generated data on welding flaws, which indicated that the largest flaws occur in weld repairs. Recent research results confirm that repair flaws are complex in composition and may include cracks on the repair ends. Section III of the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code for nuclear power plant components requires radiographic examinations (RT) of welds and requires repairs for RT indications that exceed code acceptable sizes. PNNL has previously obtained the complete construction records for two RPVs. Analysis of these records show a significant change in repair frequency.

  4. Model Repair Specifications for Low Voltage Induction Motors | Department

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    of Energy Model Repair Specifications for Low Voltage Induction Motors Model Repair Specifications for Low Voltage Induction Motors These Model Repair Specifications are intended to cover routine repair and rewind of low-voltage random-wound three-phase AC squirrel cage induction motors. Model Repair Specifications for Low Voltage Induction Motors (November 1999) (1.31 MB) More Documents & Publications DOE Navigant Master Presentation Improving Motor and Drive System Performance - A

  5. Model Repair Specifications for Low Voltage Induction Motors

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Model Repair Specifications For Low Voltage Induction Motors Model Repair Specifications for Low Voltage Induction Motors These Model Repair Specifications are intended to cover routine repair and rewind of low-voltage random-wound three-phase AC squirrel cage induction motors. For motors falling outside this description, the more comprehensive model specifications below are recommended. Electric Motor Model Repair Specifications DOE/BP-2748 Available from the U.S. Department of Energy's Office

  6. DNA repair efficiency in germ cells and early mouse embryos and consequences for radiation-induced transgenerational genomic damage

    SciTech Connect

    Marchetti, Francesco; Wyrobek, Andrew J.

    2009-01-18

    Exposure to ionizing radiation and other environmental agents can affect the genomic integrity of germ cells and induce adverse health effects in the progeny. Efficient DNA repair during gametogenesis and the early embryonic cycles after fertilization is critical for preventing transmission of DNA damage to the progeny and relies on maternal factors stored in the egg before fertilization. The ability of the maternal repair machinery to repair DNA damage in both parental genomes in the fertilizing egg is especially crucial for the fertilizing male genome that has not experienced a DNA repair-competent cellular environment for several weeks prior to fertilization. During the DNA repair-deficient period of spermatogenesis, DNA lesions may accumulate in sperm and be carried into the egg where, if not properly repaired, could result in the formation of heritable chromosomal aberrations or mutations and associated birth defects. Studies with female mice deficient in specific DNA repair genes have shown that: (i) cell cycle checkpoints are activated in the fertilized egg by DNA damage carried by the sperm; and (ii) the maternal genotype plays a major role in determining the efficiency of repairing genomic lesions in the fertilizing sperm and directly affect the risk for abnormal reproductive outcomes. There is also growing evidence that implicates DNA damage carried by the fertilizing gamete as a mediator of postfertilization processes that contribute to genomic instability in subsequent generations. Transgenerational genomic instability most likely involves epigenetic mechanisms or error-prone DNA repair processes in the early embryo. Maternal and embryonic DNA repair processes during the early phases of mammalian embryonic development can have far reaching consequences for the genomic integrity and health of subsequent generations.

  7. Energy and Technology Review: Unlocking the mysteries of DNA repair

    SciTech Connect

    Quirk, W.A.

    1993-04-01

    DNA, the genetic blueprint, has the remarkable property of encoding its own repair following diverse types of structural damage induced by external agents or normal metabolism. We are studying the interplay of DNA damaging agents, repair genes, and their protein products to decipher the complex biochemical pathways that mediate such repair. Our research focuses on repair processes that correct DNA damage produced by chemical mutagens and radiation, both ionizing and ultraviolet. The most important type of DNA repair in human cells is called excision repair. This multistep process removes damaged or inappropriate pieces of DNA -- often as a string of 29 nucleotides containing the damage -- and replaces them with intact ones. We have isolated, cloned, and mapped several human repair genes associated with the nucleotide excision repair pathway and involved in the repair of DNA damage after exposure to ultraviolet light or mutagens in cooked food. We have shown that a defect in one of these repair genes, ERCC2, is responsible for the repair deficiency in one of the groups of patients with the recessive genetic disorder xeroderma pigmentosum (XP group D). We are exploring ways to purify sufficient quantities (milligrams) of the protein products of these and other repair genes so that we can understand their functions. Our long-term goals are to link defective repair proteins to human DNA repair disorders that predispose to cancer, and to produce DNA-repair-deficient mice that can serve as models for the human disorders.

  8. INTERNAL REPAIR OF GAS PIPLINES SURVEY OF OPERATOR EXPERIENCE AND INDUSTRY NEEDS REPORT

    SciTech Connect

    Ian D. Harris

    2003-09-01

    A repair method that can be applied from the inside of a gas transmission pipeline (i.e., a trenchless repair) is an attractive alternative to conventional repair methods since the need to excavate the pipeline is precluded. This is particularly true for pipelines in environmentally sensitive and highly populated areas. The objectives of the project are to evaluate, develop, demonstrate, and validate internal repair methods for pipelines; develop a functional specification for an internal pipeline repair system; and prepare a recommended practice for internal repair of pipelines. The purpose of this survey is to better understand the needs and performance requirements of the natural gas transmission industry regarding internal repair. A total of fifty-six surveys were sent to pipeline operators. A total of twenty completed surveys were returned, representing a 36% response rate, which is considered very good given the fact that tailored surveys are known in the marketing industry to seldom attract more than a 10% response rate. The twenty survey responses produced the following principal conclusions: (1) Use of internal weld repair is most attractive for river crossings, under other bodies of water (e.g., lakes and swamps) in difficult soil conditions, under highways, under congested intersections, and under railway crossings. All these areas tend to be very difficult and very costly if, and where, conventional excavated repairs may be currently used. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling (HDD) when a new bore must be created to solve a leak or other problem in a water/river crossing. (3) The typical travel distances required can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). In concept, these groups require pig-based systems; despooled umbilical systems could be considered for the first two groups

  9. HANFORD SITE LOW EXPOSURE PIPELINE REPAIR USING A NON-METALLIC COMPOSITE SYSTEM

    SciTech Connect

    HUTH RJ

    2009-11-12

    At the Department of Energy, Richland Operations (DOE-RL) Hanford site in eastern Washington, a 350 mm (14 inch) diameter high density polyethylene (HDPE) pump recirculation pipeline failed at a bonded joint adjacent to a radiologically and chemically contaminated groundwater storage basin. The responsible DOE-RL contractor, CH2MHill Plateau Remediation Company, applied a fiberglass reinforced plastic (composite) field repair system to the failed joint. The system was devised specifically for the HDPE pipe repair at the Hanford site, and had not been used on this type of plastic piping previously. This paper introduces the pipe failure scenario, describes the options considered for repair and discusses the ultimate resolution of the problem. The failed pipeline was successfully returned to service with minimal impact on waste water treatment plant operating capacity. Additionally, radiological and chemical exposures to facility personnel were maintained as low as reasonably achievable (ALARA). The repair is considered a success for the near term, and future monitoring will prove whether the repair can be considered for long term service and as a viable alternative for similar piping failures at the Hanford site.

  10. Composite vascular repair grafts via micro-imprinting and electrospinning

    SciTech Connect

    Liu, Yuanyuan Hu, Qingxi; Xiang, Ke Chen, Haiping Li, Yu

    2015-04-15

    Composite vascular grafts formed by micro-imprinting and electrospinning exhibited improved mechanical properties relative to those formed by electrospinning alone. The three-layered composite grafts mimic the three-layered structure of natural blood vessels. The middle layer is made by micro-imprinting poly-p-dioxanone (PPDO), while the inner and outer layers are electrospun mixtures of chitosan and polyvinyl alcohol. The graft morphology is characterized with scanning electron microscopy. For constant graft thicknesses, the PPDO increases the mechanical strength. Cells cultivated on the vascular grafts adhere and proliferate better because of the natural, biological chitosan in the inner and outer layers. Overall, the composite scaffolds could be good candidates for blood vessel repair.

  11. Alkylation damage repair in mammalian genomes

    SciTech Connect

    Mitra, S.; Roy, R.; Kim, N.K. |; Tano, K. |; Ibeanu, G.C. |; Dunn, W.C.; Natarajan, A.T.; Hartenstein, B.; Kaina, B.

    1992-11-01

    The repair of O{sup 6} -alkylguanine in DNA involves only O{sup 6} -methyltransferase (MGMT) while the repair of N-alkylpurines requires multiple proteins including N-methylpurine-DNA glycosylase (MPG). While the biochemical properties human and mouse MGMTs are very similar, the mouse MPG removes 7-methylguanine more efficiently than the human protein. An increased level of MGMT, without a change in the level of MPG associated with gene amplification, was observed in a mouse cell line resistant to 2-chloroethyl-N-nitrosourea. In contrast, no correlation was observed between MPG level and resistance to methyl methanesulfonate in Chinese hamster ovary (CHO) cells. This result suggests a protein other than MPG limits the repair rate of N-alkylpurine in CHO cells.

  12. Alkylation damage repair in mammalian genomes

    SciTech Connect

    Mitra, S.; Roy, R.; Kim, N.K. . Sealy Center for Molecular Science Oak Ridge National Lab., TN ); Tano, K. Oak Ridge National Lab., TN ); Ibeanu, G.C. Oak Ridge National Lab., TN ); Dunn, W.C. (

    1992-01-01

    The repair of O{sup 6} -alkylguanine in DNA involves only O{sup 6} -methyltransferase (MGMT) while the repair of N-alkylpurines requires multiple proteins including N-methylpurine-DNA glycosylase (MPG). While the biochemical properties human and mouse MGMTs are very similar, the mouse MPG removes 7-methylguanine more efficiently than the human protein. An increased level of MGMT, without a change in the level of MPG associated with gene amplification, was observed in a mouse cell line resistant to 2-chloroethyl-N-nitrosourea. In contrast, no correlation was observed between MPG level and resistance to methyl methanesulfonate in Chinese hamster ovary (CHO) cells. This result suggests a protein other than MPG limits the repair rate of N-alkylpurine in CHO cells.

  13. Solar Water Heating System Maintenance and Repair | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Water Heating System Maintenance and Repair Solar Water Heating System Maintenance and Repair May 30, 2012 - 2:35pm Addthis Rooftop solar water heaters need regular maintenance to...

  14. Protein Bridges DNA Base and Nucleotide Excision Repair Pathways

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    ... It turns out that ATL bridges two DNA repair pathways (base repair and nucleotide excision ... By mapping conservation of amino acid sequences between their ATL and sequences in other ...

  15. Selected Bibliography on Electric Motor Repair | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Selected Bibliography on Electric Motor Repair Selected Bibliography on Electric Motor Repair The following series of repair documents related to electric motors were produced by the U.S. Department of Energy's Advanced Manufacturing Office (formerly the Office of Industrial Technologies) with input from trade associations, consulting companies, manufacturers, non-profit operations, and others. Selected Bibliography on Electric Motor Repair (November 1999) (1.38 MB) More Documents &

  16. Antibody specific for a DNA repair protein

    DOEpatents

    Petrini, John H.; Morgan, William Francis; Maser, Richard Scott; Carney, James Patrick

    2006-07-11

    An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

  17. DNA encoding a DNA repair protein

    DOEpatents

    Petrini, John H.; Morgan, William Francis; Maser, Richard Scott; Carney, James Patrick

    2006-08-15

    An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

  18. Component Repair Times Obtained from MSPI Data

    SciTech Connect

    Eide, Steven A.

    2015-05-01

    Information concerning times to repair or restore equipment to service given a failure is valuable to probabilistic risk assessments (PRAs). Examples of such uses in modern PRAs include estimation of the probability of failing to restore a failed component within a specified time period (typically tied to recovering a mitigating system before core damage occurs at nuclear power plants) and the determination of mission times for support system initiating event (SSIE) fault tree models. Information on equipment repair or restoration times applicable to PRA modeling is limited and dated for U.S. commercial nuclear power plants. However, the Mitigating Systems Performance Index (MSPI) program covering all U.S. commercial nuclear power plants provides up-to-date information on restoration times for a limited set of component types. This paper describes the MSPI program data available and analyzes the data to obtain median and mean component restoration times as well as non-restoration cumulative probability curves. The MSPI program provides guidance for monitoring both planned and unplanned outages of trains of selected mitigating systems deemed important to safety. For systems included within the MSPI program, plants monitor both train UA and component unreliability (UR) against baseline values. If the combined system UA and UR increases sufficiently above established baseline results (converted to an estimated change in core damage frequency or CDF), a “white” (or worse) indicator is generated for that system. That in turn results in increased oversight by the US Nuclear Regulatory Commission (NRC) and can impact a plant’s insurance rating. Therefore, there is pressure to return MSPI program components to service as soon as possible after a failure occurs. Three sets of unplanned outages might be used to determine the component repair durations desired in this article: all unplanned outages for the train type that includes the component of interest, only

  19. Emergency pipe line repair connects subsea pipe lines

    SciTech Connect

    Lerique, M.P.; Thiberge, P. ); Wright, N. )

    1990-11-01

    Emergency repair of any subsea line pipe must form a high-integrity, metal-to-metal seal. This paper presents a remote, diverless repair system that utilizes master flanges, a connector and a spool piece to repair line pipe in deep offshore waters.

  20. Manual of bearing failures and repair in power plant rotating equipment

    SciTech Connect

    Pinkus, O. )

    1991-07-01

    Turbine bearing failures in electric utilities have been responsible for outages amounting to 1.1 to 1.8% of theoretical power output. In addition to bearing failures in the turbo-generators, failures occur in other rotating equipment, such as pumps, fans, and auxiliary gas turbines. Knowledge of bearing failure mechanisms and causes permits the introduction of safeguards to prevent their occurrence. The Electric Power Research Institute (EPRI) has commissioned Mechanical Technology Incorporated (MTI) under EPRI contract RP1648-10 to write a bearing failure manual geared directly to bearing problems typical of the rotating equipment in electric utility power plants. The main purpose of the manual is to provide power plant engineering and service personnel with ways to properly identify specific modes of bearing damage, as well as root causes, followed by a list of remedial actions applicable to each specific case. The repair manual is a comprehensive encyclopedia on the subject of bearing failure and cause diagnosis. The manual is organized along the following lines. It first classifies 16 modes of bearing failure that are likely to occur in the rotating equipment of an electric utility. These modes are listed in the bearing failure code tabulation that follows. Each mode of failure is described in the manual regarding its symptoms and characteristics, and each is accompanied by photographs of the damaged surface. The visual aids, together with additional laboratory evidence described in the text, offer the tools for a correct diagnosis of the mode of failure. 105 refs., 222 figs., 18 tabs.

  1. New Technologies for Repairing Aging Cables in Nuclear Power Plants

    SciTech Connect

    Simmons, Kevin L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fifield, Leonard S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Westman, Matthew P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-09-11

    The goal of this project is to demonstrate a proof-of-concept for a technique to repair aging cables that have been subjected to degradation associated with long-term thermal and radiation exposure in nuclear power plants. The physical degradation of the aging cables manifests itself primarily as cracking and increased brittleness of the polymeric electrical insulation. Therefore, the proposed cable-repair concept comprises development of techniques to impart a softening agent within the deteriorated polymer insulation jacket so as to regain the ability of the insulation to stretch without failing and possibly to heal existing cracks in the insulation. Our approach is to use commercially available ethylene-propylene rubber (EPR) as the relevant test material, demonstrate the adsorption of chemical treatments in the EPR and quantify changes in resulting physical and mechanical properties. EPR cable samples have been thermally treated in air to produce specimens corresponding to the full range of cable age-performance points from new (>350% elongation at break) to end-of-life (<50% elongation at break). The current focus is on two chemical treatments selected as candidates for restoring age-related cable elasticity loss: a rubber plasticizer and a reactive silane molecule. EPR specimens of 200, 150, 100, and 50% elongation at break have been soaked in the candidate chemical treatments and the kinetics of chemical uptake, measured by change in mass of the samples, has been determined. Mechanical properties as a function of aging and chemical treatment have been measured including ultimate tensile strength, tensile modulus at 50% strain, elongation at break, and storage modulus. Dimensional changes with treatment and changes in glass transition temperature were also investigated. These ongoing experiments are expected to provide insight into the physical-chemical nature of the effect of thermal degradation on EPR rejuvenation limits and to advance novel methods for

  2. Helium bubble distributions in reactor tank repair specimens. Part 1

    SciTech Connect

    Tosten, M.H.; Kestin, P.A.

    1992-03-01

    This report discusses the Reactor Tank Repair (RTR) program was initiated to develop an in-tank repair process capable of repairing stress corrosion cracks within the SRS reactor tank walls, in the event that such a repair is needed. Previous attempts to repair C-reactor tank with a gas tungsten arc (GTA) welding process were unsuccessful due to significant cracking that occurred in the heat-affected-zones adjacent to the repair welds. It was determined that this additional cracking was a result of helium embrittlement caused by the combined effects of helium (existing within the tank walls), the high heat input associated with the GTA process, and weld shrinkage stresses. Based on the results of earlier studies it was suggested that the effects of helium embrittlement could be minimized by using a low heat input GMA process. Metallographic analysis played an important role throughout the investigation of alternative welding methods for the repair of helium-containing materials.

  3. Helium bubble distributions in reactor tank repair specimens

    SciTech Connect

    Tosten, M.H.; Kestin, P.A.

    1992-03-01

    This report discusses the Reactor Tank Repair (RTR) program was initiated to develop an in-tank repair process capable of repairing stress corrosion cracks within the SRS reactor tank walls, in the event that such a repair is needed. Previous attempts to repair C-reactor tank with a gas tungsten arc (GTA) welding process were unsuccessful due to significant cracking that occurred in the heat-affected-zones adjacent to the repair welds. It was determined that this additional cracking was a result of helium embrittlement caused by the combined effects of helium (existing within the tank walls), the high heat input associated with the GTA process, and weld shrinkage stresses. Based on the results of earlier studies it was suggested that the effects of helium embrittlement could be minimized by using a low heat input GMA process. Metallographic analysis played an important role throughout the investigation of alternative welding methods for the repair of helium-containing materials.

  4. Approaching Problems in Particle and Nuclear Physics with Time...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Approaching Problems in Particle and Nuclear Physics with Time-Dependent Quantum Mechanics (Wednesday, Jan 20) Approaching Problems in Particle and Nuclear Physics with...

  5. Restore: Modeling Repair and Restoration Processes | Argonne National

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Laboratory Restore: Modeling Repair and Restoration Processes Restore: Modeling Repair and Restoration Processes Argonne's Restore software models complex sets of steps required to accomplish a goal, such as repairing a ruptured natural gas pipeline, when the time required to complete a step may be uncertain. For example, external conditions (i.e., the time of day, weather, and availability of crew) may affect one or more of the steps required to accomplish a goal. Therefore,

  6. Federal Facilities Maintenance, Repair Report Calls for Action

    SciTech Connect

    Bartlett, Rosemarie

    2012-10-01

    This article is an overview of a recent report by the Federal Facilities Council on "Predicting Outcomes from Investments in Maintenance and Repair of Federal Facilities."

  7. Leveraging Service Calls and Emergency Repairs for Energy Efficiency Marketing

    Office of Energy Efficiency and Renewable Energy (EERE)

    Better Buildings Residential Network Peer Exchange Call Series: Leveraging Service Calls and Emergency Repairs, Call Slides and Discussion Summary, November 13, 2014.

  8. Advanced maintenance, inspection & repair technology for nuclear power plants

    SciTech Connect

    Hinton, B.M.

    1994-12-31

    Maintenance, inspection, and repair technology for nuclear power plants is outlined. The following topics are discussed: technology for reactor systems, reactor refueling bridge, fuel inspection system, fuel shuffling software, fuel reconstitution, CEA/RCCA/CRA inspection, vessel inspection capabilities, CRDM inspection and repair, reactor internals inspection and repair, stud tensioning system, stud/nut cleaning system, EDM machining technology, MI Cable systems, core exit T/C nozzle assemblies, technology for steam generators, genesis manipulator systems, ECT, UT penetrant inspections, steam generator repair and cleaning systems, technology for balance of plant, heat exchangers, piping and weld inspections, and turbogenerators.

  9. Window Replacement, Rehabilitation, & Repair Guides- Building America Top Innovation

    Energy.gov [DOE]

    Building America team Building Science Corporation guides contractors through several options for repairing or replacing old windows to improve air sealing and thermal performance.

  10. Occupational Radiation Exposure During Endovascular Aortic Repair

    SciTech Connect

    Sailer, Anna M.; Schurink, Geert Willem H.; Bol, Martine E. Haan, Michiel W. de Zwam, Willem H. van Wildberger, Joachim E. Jeukens, Cécile R. L. P. N.

    2015-08-15

    PurposeThe aim of the study was to evaluate the radiation exposure to operating room personnel and to assess determinants for high personal doses during endovascular aortic repair.Materials and MethodsOccupational radiation exposure was prospectively evaluated during 22 infra-renal aortic repair procedures (EVAR), 11 thoracic aortic repair procedures (TEVAR), and 11 fenestrated or branched aortic repair procedures (FEVAR). Real-time over-lead dosimeters attached to the left breast pocket measured personal doses for the first operators (FO) and second operators (SO), radiology technicians (RT), scrub nurses (SN), anesthesiologists (AN), and non-sterile nurses (NSN). Besides protective apron and thyroid collar, no additional radiation shielding was used. Procedural dose area product (DAP), iodinated contrast volume, fluoroscopy time, patient’s body weight, and C-arm angulation were documented.ResultsAverage procedural FO dose was significantly higher during FEVAR (0.34 ± 0.28 mSv) compared to EVAR (0.11 ± 0.21 mSv) and TEVAR (0.06 ± 0.05 mSv; p = 0.003). Average personnel doses were 0.17 ± 0.21 mSv (FO), 0.042 ± 0.045 mSv (SO), 0.019 ± 0.042 mSv (RT), 0.017 ± 0.031 mSv (SN), 0.006 ± 0.007 mSv (AN), and 0.004 ± 0.009 mSv (NSN). SO and AN doses were strongly correlated with FO dose (p = 0.003 and p < 0.001). There was a significant correlation between FO dose and procedural DAP (R = 0.69, p < 0.001), iodinated contrast volume (R = 0.67, p < 0.001) and left-anterior C-arm projections >60° (p = 0.02), and a weak correlation with fluoroscopy time (R = 0.40, p = 0.049).ConclusionAverage FO dose was a factor four higher than SO dose. Predictors for high personal doses are procedural DAP, iodinated contrast volume, and left-anterior C-arm projections greater than 60°.

  11. Waste minimization in an autobody repair shop

    SciTech Connect

    Baria, D.N.; Dorland, D.; Bergeron, J.T.

    1994-12-31

    This work was done to document the waste minimization incorporated in a new autobody repair facility in Hermantown, Minnesota. Humes Collision Center incorporated new waste reduction techniques when it expanded its old facilities in 1992 and it was able to achieve the benefits of cost reduction and waste reduction. Humes Collision Center repairs an average of 500 cars annually and is a very small quantity generator (VSQG) of hazardous waste, as defined by the Minnesota Pollution Control Agency (MPCA). The hazardous waste consists of antifreeze, batteries, paint sludge, refrigerants, and used oil, while the nonhazardous waste consists of cardboard, glass, paint filters, plastic, sanding dust, scrap metal, and wastewater. The hazardous and nonhazardous waste output were decreased by 72%. In addition, there was a 63% reduction in the operating costs. The waste minimization includes antifreeze recovery and recycling, reduction in unused waste paint, reduction, recovery and recycle of waste lacquer thinner for cleaning spray guns and paint cups, elimination of used plastic car bags, recovery and recycle of refrigerant, reduction in waste sandpaper and elimination of sanding dust, and elimination of waste paint filters. The rate of return on the investment in waste minimization equipment is estimated from 37% per year for the distillation unit, 80% for vacuum sanding, 146% for computerized paint mixing, 211% for the refrigerant recycler, to 588% per year for the gun washer. The corresponding payback time varies from 3 years to 2 months.

  12. Computational mechanics

    SciTech Connect

    Goudreau, G.L.

    1993-03-01

    The Computational Mechanics thrust area sponsors research into the underlying solid, structural and fluid mechanics and heat transfer necessary for the development of state-of-the-art general purpose computational software. The scale of computational capability spans office workstations, departmental computer servers, and Cray-class supercomputers. The DYNA, NIKE, and TOPAZ codes have achieved world fame through our broad collaborators program, in addition to their strong support of on-going Lawrence Livermore National Laboratory (LLNL) programs. Several technology transfer initiatives have been based on these established codes, teaming LLNL analysts and researchers with counterparts in industry, extending code capability to specific industrial interests of casting, metalforming, and automobile crash dynamics. The next-generation solid/structural mechanics code, ParaDyn, is targeted toward massively parallel computers, which will extend performance from gigaflop to teraflop power. Our work for FY-92 is described in the following eight articles: (1) Solution Strategies: New Approaches for Strongly Nonlinear Quasistatic Problems Using DYNA3D; (2) Enhanced Enforcement of Mechanical Contact: The Method of Augmented Lagrangians; (3) ParaDyn: New Generation Solid/Structural Mechanics Codes for Massively Parallel Processors; (4) Composite Damage Modeling; (5) HYDRA: A Parallel/Vector Flow Solver for Three-Dimensional, Transient, Incompressible Viscous How; (6) Development and Testing of the TRIM3D Radiation Heat Transfer Code; (7) A Methodology for Calculating the Seismic Response of Critical Structures; and (8) Reinforced Concrete Damage Modeling.

  13. Multiphasic survival curves for cells of human tumor cell lines: Induced repair or hypersensitive subpopulation?

    SciTech Connect

    Lambin, P. ||; Fertil, B.; Malaise, E.P.; Joiner, M.C.

    1994-04-01

    Survival of the cells of three human tumor cell lines of differing radiosensitivity was measured after irradiation with single doses of X rays (0.05-5 Gy). At doses below 1 Gy, cells were more radiosensitive than predicted by back-extrapolating the high-dose response. This difference was more marked for cells of the radioresistant cell lines than the radiosensitive cell line so that the {open_quotes}true{close_quotes} initial slopes of the survival curves, at very low doses, were similar for the cells of the three cell lines. This phenomenon could reflect an induced radioresistance so that low doses of X rays are more effective per gray than higher doses, because only at higher doses is there sufficient damage to trigger repair systems or other radioprotective mechanisms which can then act during the time course for repair of DNA injury. 35 refs., 2 figs.

  14. Deep patch technique for landslide repair. Final report

    SciTech Connect

    Helwany, B.M.

    1994-10-01

    The report describes the laboratory testing of the `USFS deep patch` technique and a CTI modification of this technique for repairing landslides with geosynthetic reinforcement. The technique involves replacing sections of roadway lost due to landslides on top of a geosynthetically-reinforced embankment. The CTI modification involves replacing the reinforced slope with a geosynthetically-reinforced retaining wall with a truncated base. Both techniques rely on the cantilevering ability of the reinforced mass to limit the load on the foundation with a high slide potential. The tests with road base showed that (1) both the USFS and CTI repair reduced effectively the adverse effects of local landsliding on the highway pavement by preventing crack propagation; (2) the USFS repair increased the stability of the repaired slope, which was in progressive failure, by reducing the stresses exerted on it; and (3) the CTI repair produced substantially greater stresses on its foundation due to the truncated base of the reinforced mass.

  15. Mechanisms of cellular transformation by carcinogenic agents

    SciTech Connect

    Grunberger, D.; Goff, S.P.

    1987-01-01

    This book contains 14 chapters. Some of the chapter titles are: DNA Modification by Chemical Carcinogens; Role of DNA Lesions and Repair in the Transformation of Human Cells; The Induction and Regulation of Radiogenic Transformation In Vitro: Cellular and Molecular Mechanisms; Cellular Transformation by Adenoviruses; and The fos Gene.

  16. Quantum Computing: Solving Complex Problems

    ScienceCinema

    DiVincenzo, David [IBM Watson Research Center

    2016-07-12

    One of the motivating ideas of quantum computation was that there could be a new kind of machine that would solve hard problems in quantum mechanics. There has been significant progress towards the experimental realization of these machines (which I will review), but there are still many questions about how such a machine could solve computational problems of interest in quantum physics. New categorizations of the complexity of computational problems have now been invented to describe quantum simulation. The bad news is that some of these problems are believed to be intractable even on a quantum computer, falling into a quantum analog of the NP class. The good news is that there are many other new classifications of tractability that may apply to several situations of physical interest.

  17. Fatigue response of repaired thick aluminum panels with bondline flaws

    SciTech Connect

    Conley, D.S.

    1999-03-01

    This research investigated the fatigue response of precracked 558 x 177.8 x 6.35 mm (22.0 x 7.0 x 0.25 in) 2024-T351 aluminum panels repaired with single-sided partially bonded, unidirectional, eighteen ply boron/epoxy reinforcements. Disbonds were introduced into the bondline of each repair during the adhesion process using teflon inserts. Five different disbond configurations, with varying disbond locations and sizes, were tested. Each repaired panel was subjected to constant amplitude cyclic fatigue loading with a maximum stress of 120MPa. Results from the different configurations were compared against one another and against repaired panels with no debonds to assess the effect of disbonds on repair life. Results from the experimentation showed that even in the case of very large disbonds (20% of total bond area), the bonded repairs significantly extended the lives of the cracked panels. Disbond configurations with disbonds located away from the crack in the aluminum panel, performed comparably to the repaired panel with no disbonds. Disbond configurations with disbonds covering the crack in the aluminum panel yielded slightly lower lives than those obtained from repaired panels with no disbonds. Cyclic fatigue loading caused no increase in size of the artificially induced disbonds. Cyclic disbond growth was observed in the immediate vicinity of the crack. Finite element analysis using the Three Layer Technique was performed to assess the ability of current modeling techniques in predicting the life of cracked thick aluminum panels repaired with composite patches. Results from the finite element analysis were shown to very closely match experimental data.

  18. Bearing repair services offer a cost-effective alternative to expensive replacement

    SciTech Connect

    2009-02-15

    The article, based on a presentation during MINExpo 2008, explains how advancement is bearing design, material, maintenance and repair methods have greatly improved the potential for and popularity of bearing repair as an effective way to extend bearing life. The Trinken Co. offers a variety of service options including repair, recertification, reconditioning and remanufacturing. Benefits of a quality repair program are outlined. 2 photos.

  19. Intermediate hearth repair technique at Thyssen Stahl AG

    SciTech Connect

    Kowalski, W.; Bachhofen, H.J.; Ruether, P.; Ballewski, T.

    1996-12-31

    Nowadays various techniques for the fastest possible intermediate repair and/or emplacement of refractory materials above the tuyere level allow a significant extension of furnace campaign life. The latter are hence now exclusively determined by the service life of the hearth. The improvement of hearth monitoring and the estimation of residual brick strength of the refractory lining on the basis of temperature measurements in the hearth enable the location of individual zones of premature wear. These measurement methods, which were developed by Thyssen Stahl AG, aid the decision to undertake selective repair of the hearth. Three areas of repair are differentiated: taphole zone; hearth wall, localized; and hearth wall, extensive. This hearth repair method is described in this report using the example of hearth refurbishing blast furnace 8, Hamborn.

  20. To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    January 29, 2007 6:28 PM To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Larry, Regarding the planned line outage, scheduled for Feb. 20 through Mar...

  1. Battery, heal thyself: Inventing self-repairing batteries | Argonne...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Battery, heal thyself: Inventing self-repairing batteries By Louise Lerner * January 11, 2012 Tweet EmailPrint Imagine dropping your phone on the hard concrete sidewalk-but when...

  2. Repairing Windows & Doors: How To's for the Handy Homeowner

    SciTech Connect

    2006-01-05

    This brochure contains tips for homeowners to repair windows and doors in their home that sustained hurricane damage. This publication is a part of the How To's for the Handy Homeowner Series.

  3. Repairing Walls & Floors: How To's for the Handy Homeowner

    SciTech Connect

    2006-01-09

    This brochure provides handy homeowners with tips on how to properly repair walls and floors in their homes that sustained damage during a hurricane. This publications is a part of the How To's for the Handy Homeowner Series.

  4. Repairing Roofs and Ceilings: How To's for the Handy Homeowner

    SciTech Connect

    2006-01-01

    This brochure provides handy homeowners with tips on how to properly repair roofs and ceilings in their homes that sustained damage during a hurricane. This publications is a part of the How To's for the Handy Homeowner Series.

  5. Inspect and Repair Steam Traps - Steam Tip Sheet #1

    SciTech Connect

    2012-01-31

    This revised AMO tip sheet on inspecting and repairing steam traps provides how-to advice for improving industrial steam systems using low-cost, proven practices and technologies.

  6. Dofasco`s No. 4 blast furnace hearth breakout, repair and rescue

    SciTech Connect

    Donaldson, R.J.; Fischer, A.J.; Sharp, R.M.; Stothart, D.W.

    1995-12-01

    On May 5, 1994, after producing 9.5 million metric tons of iron, Dofasco`s No. 4 Blast Furnace experienced a hearth breakout 250 millimeters below the west taphole. The hot metal spill caused a fire resulting in severe damage and 33 days of lost production. During a 26-day period, electrical wiring, water drainage systems and both tapholes were repaired. Recovery from an unprepared furnace stop of this length, with the deadman depleted is difficult. To aid with the rescue Hoogovens-designed oxygen/fuel lances were commissioned. The furnace recovery began with a lance in each taphole and all tuyeres plugged. Six days after startup the furnace was casting into torpedo cars, and after nine days operation had returned to normal. This incident prompted Dofasco to expand the hearth monitoring system to detect and prevent similar occurrences. During the repair, 203 new thermocouples were installed in the hearth, concentrating on the tapholes and elephant foot areas. These thermocouples were installed at various depths and locations to allow heat flux calculations. This hearth monitoring system has already identified other problem areas and provided valuable information about hearth drainage patterns. This information has allowed them to develop control strategies to manage localized problem areas.

  7. Cadmium sulfate and CdTe-quantum dots alter DNA repair in zebrafish (Danio rerio) liver cells

    SciTech Connect

    Tang, Song; Cai, Qingsong; Chibli, Hicham; Allagadda, Vinay; Nadeau, Jay L.; Mayer, Gregory D.

    2013-10-15

    Increasing use of quantum dots (QDs) makes it necessary to evaluate their toxicological impacts on aquatic organisms, since their contamination of surface water is inevitable. This study compares the genotoxic effects of ionic Cd versus CdTe nanocrystals in zebrafish hepatocytes. After 24 h of CdSO{sub 4} or CdTe QD exposure, zebrafish liver (ZFL) cells showed a decreased number of viable cells, an accumulation of Cd, an increased formation of reactive oxygen species (ROS), and an induction of DNA strand breaks. Measured levels of stress defense and DNA repair genes were elevated in both cases. However, removal of bulky DNA adducts by nucleotide excision repair (NER) was inhibited with CdSO{sub 4} but not with CdTe QDs. The adverse effects caused by acute exposure of CdTe QDs might be mediated through differing mechanisms than those resulting from ionic cadmium toxicity, and studying the effects of metallic components may be not enough to explain QD toxicities in aquatic organisms. - Highlights: • Both CdSO{sub 4} and CdTe QDs lead to cell death and Cd accumulation. • Both CdSO{sub 4} and CdTe QDs induce cellular ROS generation and DNA strand breaks. • Both CdSO{sub 4} and CdTe QDs induce the expressions of stress defense and DNA repair genes. • NER repair capacity was inhibited with CdSO{sub 4} but not with CdTe QDs.

  8. Meiotic interstrand DNA damage escapes paternal repair and causes chromosomal aberrations in the zygote by maternal misrepair

    SciTech Connect

    Marchetti, Francesco; Bishop, Jack; Gingerich, John; Wyrobek, Andrew J.

    2015-01-08

    De novo point mutations and chromosomal structural aberrations (CSA) detected in offspring of unaffected parents show a preferential paternal origin with higher risk for older fathers. Studies in rodents suggest that heritable mutations transmitted from the father can arise from either paternal or maternal misrepair of damaged paternal DNA, and that the entire spermatogenic cycle can be at risk after mutagenic exposure. Understanding the susceptibility and mechanisms of transmission of paternal mutations is important in family planning after chemotherapy and donor selection for assisted reproduction. We report that treatment of male mice with melphalan (MLP), a bifunctional alkylating agent widely used in chemotherapy, induces DNA lesions during male mouse meiosis that persist unrepaired as germ cells progress through DNA repair-competent phases of spermatogenic development. After fertilization, unrepaired sperm DNA lesions are mis-repaired into CSA by the egg's DNA repair machinery producing chromosomally abnormal offspring. In conclusion, these findings highlight the importance of both pre- and post-fertilization DNA repair in assuring the genomic integrity of the conceptus.

  9. Meiotic interstrand DNA damage escapes paternal repair and causes chromosomal aberrations in the zygote by maternal misrepair

    DOE PAGES [OSTI]

    Marchetti, Francesco; Bishop, Jack; Gingerich, John; Wyrobek, Andrew J.

    2015-01-08

    De novo point mutations and chromosomal structural aberrations (CSA) detected in offspring of unaffected parents show a preferential paternal origin with higher risk for older fathers. Studies in rodents suggest that heritable mutations transmitted from the father can arise from either paternal or maternal misrepair of damaged paternal DNA, and that the entire spermatogenic cycle can be at risk after mutagenic exposure. Understanding the susceptibility and mechanisms of transmission of paternal mutations is important in family planning after chemotherapy and donor selection for assisted reproduction. We report that treatment of male mice with melphalan (MLP), a bifunctional alkylating agent widelymore » used in chemotherapy, induces DNA lesions during male mouse meiosis that persist unrepaired as germ cells progress through DNA repair-competent phases of spermatogenic development. After fertilization, unrepaired sperm DNA lesions are mis-repaired into CSA by the egg's DNA repair machinery producing chromosomally abnormal offspring. In conclusion, these findings highlight the importance of both pre- and post-fertilization DNA repair in assuring the genomic integrity of the conceptus.« less

  10. Explore: Mechanical Engineering

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Mechanical Engineering Explore a Career: Mechanical Engineering The work of mechanical engineers can be seen in everything from the design and fabrication of space-based custom instrumentation, to the development of new, innovative solutions for the nation's nuclear security problems. Super Cam and Chem Cam photographed to scale. Super Cam and Chem Cam photographed to scale. At Los Alamos National Laboratory, there is no shortage of challenge and career excitement for our highly skilled

  11. Exposure Evaluation for Benzene, Lead and Noise in Vehicle and Equipment Repair Shops

    SciTech Connect

    Sweeney, Lynn C.

    2013-04-01

    An exposure assessment was performed at the equipment and vehicle maintenance repair shops operating at the U. S. Department of Energy Hanford site, in Richland, Washington. The maintenance shops repair and maintain vehicles and equipment used in support of the Hanford cleanup mission. There are three general mechanic shops and one auto body repair shop. The mechanics work on heavy equipment used in construction, cranes, commercial motor vehicles, passenger-type vehicles in addition to air compressors, generators, and farm equipment. Services include part fabrication, installation of equipment, repair and maintenance work in the engine compartment, and tire and brake services. Work performed at the auto body shop includes painting and surface preparation which involves applying body filler and sanding. 8-hour time-weighted-average samples were collected for benzene and noise exposure and task-based samples were collected for lead dust work activities involving painted metal surfaces. Benzene samples were obtained using 3M™ 3520 sampling badges and were analyzed for additional volatile organic compounds. These compounds were selected based on material safety data sheet information for the aerosol products used by the mechanics for each day of sampling. The compounds included acetone, ethyl ether, toluene, xylene, VM&P naphtha, methyl ethyl ketone, and trichloroethylene. Laboratory data for benzene, VM&P naphtha, methyl ethyl ketone and trichloroethylene were all below the reporting detection limit. Airborne concentrations for acetone, ethyl ether, toluene and xylene were all less than 10% of their occupational exposure limit. The task-based samples obtained for lead dusts were submitted for a metal scan analysis to identify other metals that might be present. Laboratory results for lead dusts were all below the reporting detection limit and airborne concentration for the other metals observed in the samples were less than 10% of the occupational exposure limit

  12. Microfabricated therapeutic actuator mechanisms

    DOEpatents

    Northrup, M.A.; Ciarlo, D.R.; Lee, A.P.; Krulevitch, P.A.

    1997-07-08

    Electromechanical microstructures (microgrippers), either integrated circuit (IC) silicon-based or precision machined, to extend and improve the application of catheter-based interventional therapies for the repair of aneurysms in the brain or other interventional clinical therapies. These micromechanisms can be specifically applied to release platinum coils or other materials into bulging portions of the blood vessels also known as aneurysms. The ``micro`` size of the release mechanism is necessary since the brain vessels are the smallest in the body. Through a catheter more than one meter long, the micromechanism located at one end of the catheter can be manipulated from the other end thereof. The microgripper (micromechanism) of the invention will also find applications in non-medical areas where a remotely actuated microgripper or similar actuator would be useful or where micro-assembling is needed. 22 figs.

  13. Microfabricated therapeutic actuator mechanisms

    DOEpatents

    Northrup, Milton A.; Ciarlo, Dino R.; Lee, Abraham P.; Krulevitch, Peter A.

    1997-01-01

    Electromechanical microstructures (microgrippers), either integrated circuit (IC) silicon-based or precision machined, to extend and improve the application of catheter-based interventional therapies for the repair of aneurysms in the brain or other interventional clinical therapies. These micromechanisms can be specifically applied to release platinum coils or other materials into bulging portions of the blood vessels also known as aneurysms. The "micro" size of the release mechanism is necessary since the brain vessels are the smallest in the body. Through a catheter more than one meter long, the micromechanism located at one end of the catheter can be manipulated from the other end thereof. The microgripper (micromechanism) of the invention will also find applications in non-medical areas where a remotely actuated microgripper or similar actuator would be useful or where micro-assembling is needed.

  14. LENS repair and modification of metal NW components:materials and applications guide.

    SciTech Connect

    Smugeresky, John E. (Sandia National Laboratories, Livermore, CA); Gill, David Dennis; Oberhaus, Jason (BWXT Y-12); Adams, Thad; VanCamp, Chad

    2006-11-01

    Laser Engineered Net Shaping{trademark} (LENS{reg_sign}) is a unique, layer additive, metal manufacturing technique that offers the ability to create fully dense metal features and components directly from a computer solid model. LENS offers opportunities to repair and modify components by adding features to existing geometry, refilling holes, repairing weld lips, and many other potential applications. The material deposited has good mechanical properties with strengths typically slightly higher that wrought material due to grain refinement from a quickly cooling weld pool. The result is a material with properties similar to cold worked material, but without the loss in ductility traditionally seen with such treatments. Furthermore, 304L LENS material exhibits good corrosion resistance and hydrogen compatibility. This report gives a background of the LENS process including materials analysis addressing the requirements of a number of different applications. Suggestions are given to aid both the product engineer and the process engineer in the successful utilization of LENS for their applications. The results of testing on interface strength, machinability, weldability, corrosion resistance, geometric effects, heat treatment, and repair strategy testing are all included. Finally, the qualification of the LENS process is briefly discussed to give the user confidence in selecting LENS as the process of choice for high rigor applications. The testing showed LENS components to have capability in repair/modification applications requiring complex castings (W80-3 D-Bottle bracket), thin wall parts requiring metal to be rebuilt onto the part (W87 Firing Set Housing and Y-12 Test Rings), the filling of counterbores for use in reservoir reclamation welding (SRNL hydrogen compatibility study) and the repair of surface defects on pressure vessels (SRNL gas bottle repair). The material is machinable, as testing has shown that LENS deposited material machines similar to that of

  15. Table Definitions, Sources, and Explanatory Notes

    Gasoline and Diesel Fuel Update

    inspection, maintenance, repairs, and turnaround; and the reduction of capacity for unscheduled downtime due to such conditions as mechanical problems, repairs, and slowdowns. ...

  16. Chemical repair of base lesions, AP-sites, and strand breaks on plasmid DNA in dilute aqueous solution by ascorbic acid

    SciTech Connect

    Hata, Kuniki; Advanced Science Research Center, Japan Atomic Energy Agency, 2-4 Shirakatashirane, Tokai-mura, Naka-gun, Ibaraki 319-1195 ; Urushibara, Ayumi; Yamashita, Shinichi; Shikazono, Naoya; Yokoya, Akinari; Katsumura, Yosuke; Nuclear Professional School, School of Engineering, The University of Tokyo, 2-22 Shirakatashirane, Tokai-mura, Naka-gun, Ibaraki 319-1188

    2013-05-03

    Highlights: We report a novel mechanism of radiation protection of DNA by chemical activity of ascorbic acid. The chemical repair of DNA damage was revealed using biochemical assay and chemical kinetics analysis. We found that ascorbic acid significantly repairs precursors of nucleobase lesions and abasic sites. However, ascorbic acid seldom repairs precursors of DNA-strand breaks. -- Abstract: We quantified the damage yields produced in plasmid DNA by ?-irradiation in the presence of low concentrations (10100 ?M) of ascorbic acid, which is a major antioxidant in living systems, to clarify whether it chemically repairs radiation damage in DNA. The yield of DNA single strand breaks induced by irradiation was analyzed with agarose gel electrophoresis as conformational changes in closed circular plasmids. Base lesions and abasic sites were also observed as additional conformational changes by treating irradiated samples with glycosylase proteins. By comparing the suppression efficiencies to the induction of each DNA lesion, in addition to scavenging of the OH radicals derived from water radiolysis, it was found that ascorbic acid promotes the chemical repair of precursors of AP-sites and base lesions more effectively than those of single strand breaks. We estimated the efficiency of the chemical repair of each lesion using a kinetic model. Approximately 5060% of base lesions and AP-sites were repaired by 10 ?M ascorbic acid, although strand breaks were largely unrepaired by ascorbic acid at low concentrations. The methods in this study will provide a route to understanding the mechanistic aspects of antioxidant activity in living systems.

  17. Ice plug employed on subsea pipeline bend during repair

    SciTech Connect

    1997-12-22

    The first controlled-temperature ice plug in the bend of an offshore gas trunkline has been carried out for Phillips Petroleum Co. Norway on its Norpipe A.S. platform in the German sector of the North Sea. The procedure was part of a subsea valve repair operation. The ice plug was successfully formed offshore and tested to a differential pressure of 1,450 psi. Repair of two valves required only 5 days during which time gas production was operating at close to 50--60% via the platform bypass, says the service company. The paper discusses the procedure.

  18. Patient Compliance with Surveillance Following Elective Endovascular Aneurysm Repair

    SciTech Connect

    Godfrey, Anthony D. Morbi, Abigail H. M. Nordon, Ian M.

    2015-10-15

    PurposeIntegral to maintaining good outcomes post-endovascular aneurysm repair (EVAR) is a robust surveillance protocol. A significant proportion of patients fail to comply with surveillance, exposing themselves to complications. We examine EVAR surveillance in Wessex (UK), exploring factors that may predict poor compliance.MethodsRetrospective analysis of 179 consecutive elective EVAR cases [2008–2013] was performed. 167 patients were male, with the age range of 50–95. Surveillance was conducted centrally (tertiary referral trauma centre) and at four spoke units. Surveillance compliance and predictors of non-compliance including age, gender, co-morbid status, residential location and socioeconomic status were analysed for univariate significance.ResultsFifty patients (27.9 %) were non-compliant with surveillance; 14 (8.1 %) had no imaging post-EVAR. At 1 year, 56.1 % (of 123 patients) were compliant. At years 2 and 3, 41.5 and 41.2 % (of 65 and 34 patients, respectively) were compliant. Four years post-EVAR, only one of eight attended surveillance (12.5 %). There were no statistically significant differences in age (p = 0.77), co-morbid status or gender (p = 0.64). Distance to central unit (p = 0.67) and surveillance site (p = 0.56) was non-significant. While there was a trend towards compliance in upper-middle-class socioeconomic groups (ABC1 vs. C1C2D), correlating with >50 % of non-compliant patients living within <10 mile radius of the central unit, overall predictive value was not significant (p = 0.82).ConclusionsCompliance with surveillance post-EVAR is poor. No independent predictor of non-compliance has been confirmed, but socioeconomic status appears to be relevant. There is a worrying drop-off in attendance beyond the first year. This study highlights a problem that needs to be addressed urgently, if we are to maintain good outcomes post-EVAR.

  19. Methods to alter levels of a DNA repair protein

    DOEpatents

    Petrini, John H.; Morgan, William Francis; Maser, Richard Scott; Carney, James Patrick

    2006-10-17

    An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

  20. Development of quick repairing technique for ceramic burner in hot stove of blast furnace

    SciTech Connect

    Kondo, Atsushi; Doura, Kouji; Nakamura, Hirofumi

    1997-12-31

    Refractories of ceramic burner in hot stoves at Wakayama No. 4 blast furnace were damaged. There are only three hot stoves, so repairing must be done in a short. Therefore, a quick repairing technique for ceramic burners has been developed, and two ceramic burners were repaired in just 48 hours.

  1. The Guderley problem revisited

    SciTech Connect

    Ramsey, Scott D [Los Alamos National Laboratory; Kamm, James R [Los Alamos National Laboratory; Bolstad, John H [NON LANL

    2009-01-01

    The self-similar converging-diverging shock wave problem introduced by Guderley in 1942 has been the source of numerous investigations since its publication. In this paper, we review the simplifications and group invariance properties that lead to a self-similar formulation of this problem from the compressible flow equations for a polytropic gas. The complete solution to the self-similar problem reduces to two coupled nonlinear eigenvalue problems: the eigenvalue of the first is the so-called similarity exponent for the converging flow, and that of the second is a trajectory multiplier for the diverging regime. We provide a clear exposition concerning the reflected shock configuration. Additionally, we introduce a new approximation for the similarity exponent, which we compare with other estimates and numerically computed values. Lastly, we use the Guderley problem as the basis of a quantitative verification analysis of a cell-centered, finite volume, Eulerian compressible flow algorithm.

  2. Final Report for DOE Grant DE-FG02-03ER25579; Development of High-Order Accurate Interface Tracking Algorithms and Improved Constitutive Models for Problems in Continuum Mechanics with Applications to Jetting

    SciTech Connect

    Puckett, Elbridge Gerry; Miller, Gregory Hale

    2012-10-14

    Much of the work conducted under the auspices of DE-FG02-03ER25579 was characterized by an exceptionally close collaboration with researchers at the Lawrence Berkeley National Laboratory (LBNL). For example, Andy Nonaka, one of Professor Miller's graduate students in the Department of Applied Science at U. C. Davis (UCD) wrote his PhD thesis in an area of interest to researchers in the Applied Numerical Algorithms Group (ANAG), which is a part of the National Energy Research Supercomputer Center (NERSC) at LBNL. Dr. Nonaka collaborated closely with these researchers and subsequently published the results of this collaboration jointly with them, one article in a peer reviewed journal article and one paper in the proceedings of a conference. Dr. Nonaka is now a research scientist in the Center for Computational Sciences and Engineering (CCSE), which is also part of the National Energy Research Supercomputer Center (NERSC) at LBNL. This collaboration with researchers at LBNL also included having one of Professor Puckett's graduate students in the Graduate Group in Applied Mathematics (GGAM) at UCD, Sarah Williams, spend the summer working with Dr. Ann Almgren, who is a staff scientist in CCSE. As a result of this visit Sarah decided work on a problem suggested by the head of CCSE, Dr. John Bell, for her PhD thesis. Having finished all of the coursework and examinations required for a PhD, Sarah stayed at LBNL to work on her thesis under the guidance of Dr. Bell. Sarah finished her PhD thesis in June of 2007. Writing a PhD thesis while working at one of the University of California (UC) managed DOE laboratories is long established tradition at UC and Professor Puckett has always encouraged his students to consider doing this. Another one of Professor Puckett's graduate students in the GGAM at UCD, Christopher Algieri, was partially supported with funds from DE-FG02-03ER25579 while he wrote his MS thesis in which he analyzed and extended work originally published by Dr

  3. Radiation-Induced Upregulation of Gene Expression From Adenoviral Vectors Mediated by DNA Damage Repair and Regulation

    SciTech Connect

    Nokisalmi, Petri; Rajecki, Maria; Pesonen, Sari; Escutenaire, Sophie; Soliymani, Rabah; Tenhunen, Mikko; Ahtiainen, Laura; Hemminki, Akseli

    2012-05-01

    Purpose: In the present study, we evaluated the combination of replication-deficient adenoviruses and radiotherapy in vitro. The purpose of the present study was to analyze the mechanism of radiation-mediated upregulation of adenoviral transgene expression. Methods and Materials: Adenoviral transgene expression (luciferase or green fluorescent protein) was studied with and without radiation in three cell lines: breast cancer M4A4-LM3, prostate cancer PC-3MM2, and lung cancer LNM35/enhanced green fluorescent protein. The effect of the radiation dose, modification of the viral capsid, and five different transgene promoters were studied. The cellular responses were studied using mass spectrometry and immunofluorescence analysis. Double strand break repair was modulated by inhibitors of heat shock protein 90, topoisomerase-I, and DNA protein kinase, and transgene expression was measured. Results: We found that a wide range of radiation doses increased adenoviral transgene expression regardless of the cell line, transgene, promoter, or viral capsid modification. Treatment with adenovirus, radiation, and double strand break repair inhibitors resulted in persistence of double strand breaks and subsequent increases in adenovirus transgene expression. Conclusions: Radiation-induced enhancement of adenoviral transgene expression is linked to DNA damage recognition and repair. Radiation induces a global cellular response that results in increased production of RNA and proteins, including adenoviral transgene products. This study provides a mechanistic rationale for combining radiation with adenoviral gene delivery.

  4. Sandia National Laboratories Problem

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Problem Natural disasters such as Hurricane Katrina in New Orleans and the tsunami in Japan in 2011 create emergency situations that must be dealt with quickly and effectively in...

  5. Cycling with BRCA2 from DNA repair to mitosis

    SciTech Connect

    Lee, Hyunsook

    2014-11-15

    Genetic integrity in proliferating cells is guaranteed by the harmony of DNA replication, appropriate DNA repair, and segregation of the duplicated genome. Breast cancer susceptibility gene BRCA2 is a unique tumor suppressor that is involved in all three processes. Hence, it is critical in genome maintenance. The functions of BRCA2 in DNA repair and homology-directed recombination (HDR) have been reviewed numerous times. Here, I will briefly go through the functions of BRCA2 in HDR and focus on the emerging roles of BRCA2 in telomere homeostasis and mitosis, then discuss how BRCA2 exerts distinct functions in a cell-cycle specific manner in the maintenance of genomic integrity. - Highlights: • BRCA2 is a multifaceted tumor suppressor and is crucial in genetic integrity. • BRCA2 exerts distinct functions in cell cycle-specific manner. • Mitotic kinases regulate diverse functions of BRCA2 in mitosis and cytokinesis.

  6. Thermostatic/orifice trap reduces fuel, repair costs

    SciTech Connect

    Not Available

    1982-11-01

    This article is an evaluation of a steam trap that combines the continuous drain oriface with a thermostatically controlled trap oriface to efficiently remove condensate from virtually any steam system within its operating limits. This trap effectively reduces fuel and repair costs and has a capacity of 6000 il/hr, handles various pressures up to 600 psig, and operates against back pressures up to 90% of inlet pressure.

  7. FABRICATION AND REPAIR OF ION SOURCE COMPONENTS IN THE 80 keV NEUTRAL BEAM LINES FOR DIII-D

    SciTech Connect

    GRUNLOH,H.J; BUSATH,J.L; CALLIS,R.W; CHIU,H.K; DiMARTINO,M; HONG,R; KLASEN,R; MOELLER,C.P; ROBINSON,J.I; STRECKERT,H.H; TAO,R; TRESTER,P.W

    2003-10-01

    OAK-B135 After 8 years of operation, leaks began to develop in critical components of the ion sources of the 80 keV neutral beam lines in DIII-D. Operational adjustments were made that seemed to remedy the problems, but five years later leaks began occurring again, this time with greater frequency. Failures occurred in the stainless steel bellows and molybdenum rails of the grid rail modules as well as in the Langmuir probes. Failure analyses identified several root causes of the leaks and operational adjustments were again made to mitigate the problems, but the rash of failures depleted the program's supply of spare grid rail modules and probes and removed one of the ion sources from regular operation. Fifteen years after their original fabrication, the ion source components were no longer commercially available. In 2001, a program was initiated to fabricate new grid rail modules, including new molybdenum grid rails, bellows, and stainless steel grid rail holders, as well as new Langmuir probes. In parallel, components removed from service due to leaks were to be repaired with new rails and bellows and returned to service. An overview of the root causes of the service failures is offered, details of the repair processes are described, and a summary and evaluation of the fabrication procedures for the new molybdenum rails, grid modules, and Langmuir probes are given.

  8. [Studies of the repair of radiation-induced genetic damage in Drosophila]. Annual progress report, July 1, 1991--June 1, 1992

    SciTech Connect

    1992-12-31

    The primary goal of this program is to achieve a more thorough understanding of the mechanisms employed by higher organisms to resist DNA damage. Concurrently this effort contributes to an improved understanding of the processes of mutagenesis and carcinogenesis in higher eukaryotes. Drosophila was initially chosen as a model organism for investigating functions that control mutagen resistance because of the ease with which one can isolate and characterize mutagen-sensitive mutants in this multicellular organism. This laboratory then went on to investigate the DNA repair defects of such mutants while others performed complementary genetic and cytogenetic studies which relate DNA repair processes to mutagenesis and chromosome stability. Currently, recombinant DNA technology is being employed to investigate the mechanisms of mutagen resistance defined by those mutants. The following two studies experienced the most significant progress during the past year: cloning and genetic characterization of the mus209 gene, and genetic and molecular analysis of the mus308 gene.

  9. Bicriteria network design problems

    SciTech Connect

    Marathe, M.V.; Ravi, R.; Sundaram, R.; Ravi, S.S.; Rosenkrantz, D.J.; Hunt, H.B. III

    1997-11-20

    The authors study a general class of bicriteria network design problems. A generic problem in this class is as follows: Given an undirected graph and two minimization objectives (under different cost functions), with a budget specified on the first, find a subgraph from a given subgraph class that minimizes the second objective subject to the budget on the first. They consider three different criteria -- the total edge cost, the diameter and the maximum degree of the network. Here, they present the first polynomial-time approximation algorithms for a large class of bicriteria network design problems for the above mentioned criteria. The following general types of results are presented. First, they develop a framework for bicriteria problems and their approximations. Second, when the two criteria are the same they present a black box parametric search technique. This black box takes in as input an (approximation) algorithm for the criterion situation and generates an approximation algorithm for the bicriteria case with only a constant factor loss in the performance guarantee. Third, when the two criteria are the diameter and the total edge costs they use a cluster based approach to devise approximation algorithms. The solutions violate both the criteria by a logarithmic factor. Finally, for the class of treewidth-bounded graphs, they provide pseudopolynomial-time algorithms for a number of bicriteria problems using dynamic programming. The authors show how these pseudopolynomial-time algorithms can be converted to fully polynomial-time approximation schemes using a scaling technique.

  10. Statistical mechanics based on fractional classical and quantum mechanics

    SciTech Connect

    Korichi, Z.; Meftah, M. T.

    2014-03-15

    The purpose of this work is to study some problems in statistical mechanics based on the fractional classical and quantum mechanics. At first stage we have presented the thermodynamical properties of the classical ideal gas and the system of N classical oscillators. In both cases, the Hamiltonian contains fractional exponents of the phase space (position and momentum). At the second stage, in the context of the fractional quantum mechanics, we have calculated the thermodynamical properties for the black body radiation, studied the Bose-Einstein statistics with the related problem of the condensation and the Fermi-Dirac statistics.

  11. Dynamical impurity problems

    SciTech Connect

    Emery, V.J.; Kivelson, S.A.

    1993-12-31

    In the past few years there has been a resurgence of interest in dynamical impurity problems, as a result of developments in the theory of correlated electron systems. The general dynamical impurity problem is a set of conduction electrons interacting with an impurity which has internal degrees of freedom. The simplest and earliest example, the Kondo problem, has attracted interest since the mid-sixties not only because of its physical importance but also as an example of a model displaying logarithmic divergences order by order in perturbation theory. It provided one of the earliest applications of the renormalization group method, which is designed to deal with just such a situation. As we shall see, the antiferromagnetic Kondo model is controlled by a strong-coupling fixed point, and the essence of the renormalization group solution is to carry out the global renormalization numerically starting from the original (weak-coupling) Hamiltonian. In these lectures, we shall describe an alternative route in which we identify an exactly solvable model which renormalizes to the same fixed point as the original dynamical impurity problem. This approach is akin to determining the critical behavior at a second order phase transition point by solving any model in a given universality class.

  12. Economic penalties of problems and errors in solar energy systems

    SciTech Connect

    Raman, K.; Sparkes, H.R.

    1983-01-01

    Experience with a large number of installed solar energy systems in the HUD Solar Program has shown that a variety of problems and design/installation errors have occurred in many solar systems, sometimes resulting in substantial additional costs for repair and/or replacement. In this paper, the effect of problems and errors on the economics of solar energy systems is examined. A method is outlined for doing this in terms of selected economic indicators. The method is illustrated by a simple example of a residential solar DHW system. An example of an installed, instrumented solar energy system in the HUD Solar Program is then discussed. Detailed results are given for the effects of the problems and errors on the cash flow, cost of delivered heat, discounted payback period, and life-cycle cost of the solar energy system. Conclusions are drawn regarding the most suitable economic indicators for showing the effects of problems and errors in solar energy systems. A method is outlined for deciding on the maximum justifiable expenditure for maintenance on a solar energy system with problems or errors.

  13. The inhibiting bisection problem.

    SciTech Connect

    Pinar, Ali

    2010-11-01

    Given a graph where each vertex is assigned a generation or consumption volume, we try to bisect the graph so that each part has a significant generation/consumption mismatch, and the cutsize of the bisection is small. Our motivation comes from the vulnerability analysis of distribution systems such as the electric power system. We show that the constrained version of the problem, where we place either the cutsize or the mismatch significance as a constraint and optimize the other, is NP-complete, and provide an integer programming formulation. We also propose an alternative relaxed formulation, which can trade-off between the two objectives and show that the alternative formulation of the problem can be solved in polynomial time by a maximum flow solver. Our experiments with benchmark electric power systems validate the effectiveness of our methods.

  14. One "Cool Tool" That's Helping Repair Your DNA | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    "Cool Tool" That's Helping Repair Your DNA One "Cool Tool" That's Helping Repair Your DNA April 18, 2011 - 1:20pm Addthis Charles Rousseaux Charles Rousseaux Senior Communications Specialist (detailee) What are the key facts? Berkeley Lab's Advanced Light Source produces x-ray light that shines a billion times bright than the sun. Scientists discovered the motor that drives the actual repair of the DNA repair machine called MRN, which is tethered to the rest of the machine in

  15. Building America Top Innovations 2013 Profile – Window Replacement, Rehabilitation, & Repair Guide

    SciTech Connect

    none,

    2013-09-01

    In this Top Innovation profile, Building Science Corporation guides contractors through several options for repairing or replacing old windows to improve air sealing and thermal performance.

  16. WPN 12-9: Weatherization Assistance Program Incidental Repair Measure Guidance

    Energy.gov [DOE]

    To provide guidance on incidental repair measures (IRM) allowable under the U.S. Department of Energy Weatherization Assistance Program (WAP).

  17. Brain necrosis after fractionated radiation therapy: Is the halftime for repair longer than we thought?

    SciTech Connect

    Bender, Edward T.

    2012-11-15

    Purpose: To derive a radiobiological model that enables the estimation of brain necrosis and spinal cord myelopathy rates for a variety of fractionation schemes, and to compare repair effects between brain and spinal cord. Methods: Sigmoidal dose response relationships for brain radiation necrosis and spinal cord myelopathy are derived from clinical data using nonlinear regression. Three different repair models are considered and the repair halftimes are included as regression parameters. Results: For radiation necrosis, a repair halftime of 38.1 (range 6.9-76) h is found with monoexponential repair, while for spinal cord myelopathy, a repair halftime of 4.1 (range 0-8) h is found. The best-fit alpha beta ratio is 0.96 (range 0.24-1.73)Conclusions: A radiobiological model that includes repair corrections can describe the clinical data for a variety of fraction sizes, fractionation schedules, and total doses. Modeling suggests a relatively long repair halftime for brain necrosis. This study suggests that the repair halftime for late radiation effects in the brain may be longer than is currently thought. If confirmed in future studies, this may lead to a re-evaluation of radiation fractionation schedules for some CNS diseases, particularly for those diseases where fractionated stereotactic radiation therapy is used.

  18. adaptation of DNA repair Byrne, Rose T; Klingele, Audrey J; Cabot...

    Office of Scientific and Technical Information (OSTI)

    Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair Byrne, Rose T; Klingele, Audrey J; Cabot, Eric L; Schackwitz, Wendy S; Martin, Jeffrey A;...

  19. Disruption of Maternal DNA Repair Increases Sperm-DerivedChromosomal Aberrations

    SciTech Connect

    Marchetti, Francesco; Essers, Jeroun; Kanaar, Roland; Wyrobek,Andrew J.

    2007-02-07

    The final weeks of male germ cell differentiation occur in aDNA repair-deficient environment and normal development depends on theability of the egg to repair DNA damage in the fertilizing sperm. Geneticdisruption of maternal DNA double-strand break repair pathways in micesignificantly increased the frequency of zygotes with chromosomalstructural aberrations after paternal exposure to ionizing radiation.These findings demonstrate that radiation-induced DNA sperm lesions arerepaired after fertilization by maternal factors and suggest that geneticvariation in maternal DNA repair can modulate the risk of early pregnancylosses and of children with chromosomal aberrations of paternalorigin.

  20. GRAND CHALLENGE PROBLEMS

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    GRAND CHALLENGE PROBLEMS Time is the biggest issue. Materials typically become critical in a matter of months, but solutions take years or decades to develop and implement. Our first two grand challenges address this discrepancy. Anticipating Which Materials May Go Critical In an ideal world, users of materials would anticipate supply-chain disruptions before they occur. They would undertake activities to manage the risks of disruption, including R&D to diversify and increase supplies or to

  1. Mechanical memory

    DOEpatents

    Gilkey, Jeffrey C.; Duesterhaus, Michelle A.; Peter, Frank J.; Renn, Rosemarie A.; Baker, Michael S.

    2006-08-15

    A first-in-first-out (FIFO) microelectromechanical memory apparatus (also termed a mechanical memory) is disclosed. The mechanical memory utilizes a plurality of memory cells, with each memory cell having a beam which can be bowed in either of two directions of curvature to indicate two different logic states for that memory cell. The memory cells can be arranged around a wheel which operates as a clocking actuator to serially shift data from one memory cell to the next. The mechanical memory can be formed using conventional surface micromachining, and can be formed as either a nonvolatile memory or as a volatile memory.

  2. Mechanical memory

    DOEpatents

    Gilkey, Jeffrey C.; Duesterhaus, Michelle A.; Peter, Frank J.; Renn, Rosemarie A.; Baker, Michael S.

    2006-05-16

    A first-in-first-out (FIFO) microelectromechanical memory apparatus (also termed a mechanical memory) is disclosed. The mechanical memory utilizes a plurality of memory cells, with each memory cell having a beam which can be bowed in either of two directions of curvature to indicate two different logic states for that memory cell. The memory cells can be arranged around a wheel which operates as a clocking actuator to serially shift data from one memory cell to the next. The mechanical memory can be formed using conventional surface micromachining, and can be formed as either a nonvolatile memory or as a volatile memory.

  3. Agreement Mechanisms

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Agreement Mechanisms Agreement Mechanisms World-class experts and capabilities countering all aspects of explosive threats, and aiming predominantly at enhanced detection capabilities. CRADA: Cooperative Research and Development Agreement What is it? Work performed in collaboration with a sponsor. What does it do? Enables Los Alamos staff to participate with industry, academia, and nonprofit entities on collaborative R&D activities of mutual benefit. When is it used? An organization's

  4. Analytical solutions to matrix diffusion problems

    SciTech Connect

    Keklinen, Pekka

    2014-10-06

    We report an analytical method to solve in a few cases of practical interest the equations which have traditionally been proposed for the matrix diffusion problem. In matrix diffusion, elements dissolved in ground water can penetrate the porous rock surronuding the advective flow paths. In the context of radioactive waste repositories this phenomenon provides a mechanism by which the area of rock surface in contact with advecting elements is greatly enhanced, and can thus be an important delay mechanism. The cases solved are relevant for laboratory as well for in situ experiments. Solutions are given as integral representations well suited for easy numerical solution.

  5. Evaluating indoor exposure modeling alternatives for LCA: A case study in the vehicle repair industry

    SciTech Connect

    Demou, Evangelia; Hellweg, Stefanie; Wilson, Michael P.; Hammond, S. Katharine; McKone, Thomas E.

    2009-05-01

    We evaluated three exposure models with data obtained from measurements among workers who use"aerosol" solvent products in the vehicle repair industry and with field experiments using these products to simulate the same exposure conditions. The three exposure models were the: 1) homogeneously-mixed-one-box model, 2) multi-zone model, and 3) eddy-diffusion model. Temporally differentiated real-time breathing zone volatile organic compound (VOC) concentration measurements, integrated far-field area samples, and simulated experiments were used in estimating parameters, such as emission rates, diffusivity, and near-field dimensions. We assessed differences in model input requirements and their efficacy for predictive modeling. The One-box model was not able to resemble the temporal profile of exposure concentrations, but it performed well concerning time-weighted exposure over extended time periods. However, this model required an adjustment for spatial concentration gradients. Multi-zone models and diffusion-models may solve this problem. However, we found that the reliable use of both these models requires extensive field data to appropriately define pivotal parameters such as diffusivity or near-field dimensions. We conclude that it is difficult to apply these models for predicting VOC exposures in the workplace. However, for comparative exposure scenarios in life-cycle assessment they may be useful.

  6. The Inhibiting Bisection Problem

    SciTech Connect

    Pinar, Ali; Fogel, Yonatan; Lesieutre, Bernard

    2006-12-18

    Given a graph where each vertex is assigned a generation orconsumption volume, we try to bisect the graph so that each part has asignificant generation/consumption mismatch, and the cutsize of thebisection is small. Our motivation comes from the vulnerability analysisof distribution systems such as the electric power system. We show thatthe constrained version of the problem, where we place either the cutsizeor the mismatch significance as a constraint and optimize the other, isNP-complete, and provide an integer programming formulation. We alsopropose an alternative relaxed formulation, which can trade-off betweenthe two objectives and show that the alternative formulation of theproblem can be solved in polynomial time by a maximum flow solver. Ourexperiments with benchmark electric power systems validate theeffectiveness of our methods.

  7. 21PF overpack problems

    SciTech Connect

    Kovac, F.M.

    1995-12-31

    The 21PF overpack has had severe metal corrosion and stress corrosion cracking (SCC) for many years. The US Department of Transportation (DOT) and the US Nuclear Regulatory Commission (NRC) have disallowed the use of overpacks containing high chloride foam. Corrosion and SCC of 21PF overpacks have been documented and papers have been presented at conferences about these issues. Regulatory agencies have restricted 21PF overpack use and have requested data to determine if phenolic foam overpacks not meeting original design specifications will be authorized for continued use. This paper details some of the problems experienced by users and relates actions of the DOT and NRC concerning these packages. Industry is working to correct deficiencies, but if they are not successful, the entire uranium enrichment industry will be severely impacted.

  8. Computational mechanics

    SciTech Connect

    Raboin, P J

    1998-01-01

    The Computational Mechanics thrust area is a vital and growing facet of the Mechanical Engineering Department at Lawrence Livermore National Laboratory (LLNL). This work supports the development of computational analysis tools in the areas of structural mechanics and heat transfer. Over 75 analysts depend on thrust area-supported software running on a variety of computing platforms to meet the demands of LLNL programs. Interactions with the Department of Defense (DOD) High Performance Computing and Modernization Program and the Defense Special Weapons Agency are of special importance as they support our ParaDyn project in its development of new parallel capabilities for DYNA3D. Working with DOD customers has been invaluable to driving this technology in directions mutually beneficial to the Department of Energy. Other projects associated with the Computational Mechanics thrust area include work with the Partnership for a New Generation Vehicle (PNGV) for ''Springback Predictability'' and with the Federal Aviation Administration (FAA) for the ''Development of Methodologies for Evaluating Containment and Mitigation of Uncontained Engine Debris.'' In this report for FY-97, there are five articles detailing three code development activities and two projects that synthesized new code capabilities with new analytic research in damage/failure and biomechanics. The article this year are: (1) Energy- and Momentum-Conserving Rigid-Body Contact for NIKE3D and DYNA3D; (2) Computational Modeling of Prosthetics: A New Approach to Implant Design; (3) Characterization of Laser-Induced Mechanical Failure Damage of Optical Components; (4) Parallel Algorithm Research for Solid Mechanics Applications Using Finite Element Analysis; and (5) An Accurate One-Step Elasto-Plasticity Algorithm for Shell Elements in DYNA3D.

  9. Method of tissue repair using a composite material

    DOEpatents

    Hutchens, Stacy A.; Woodward, Jonathan; Evans, Barbara R.; O'Neill, Hugh M.

    2016-03-01

    A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.

  10. Method of tissue repair using a composite material

    DOEpatents

    Hutchens, Stacy A; Woodward, Jonathan; Evans, Barbara R; O'Neill, Hugh M

    2014-03-18

    A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.

  11. DNA repair in spermatocytes and spermatids of the mouse

    SciTech Connect

    Sega, G.A.

    1982-01-01

    When male mice are exposed to chemical agents that reach the germ cells several outcomes are possible in terms of the germ cell unscheduled DNA synthesis (UDS) response and removal of DNA adducts. It is possible that: the chemical binds to the DNA and induces a UDS response with concomittant removal of DNA adducts; the chemical binds to the DNA but no UDS response is induced; or the chemical does not bind to DNA and no UDS is induced. Many mutagens have been shown to induce a UDS response in postgonial germ cell stages of the male mouse up through midspermatids, but the relationship between this UDS and the repair of genetic damage within the germ cells is still unknown. While some mutagens appear to have an effect only in germ-cell stages where no UDS occurs, others are able to induce genetic damage in stages where UDS has been induced.

  12. Assessment of Synthane mechanical equipment. Technical report

    SciTech Connect

    McCabe, J.T.; Kramberger, F.E.; Hao, B.R.; Dubis, D.; Carson, S.E.

    1980-05-01

    Mechanical equipment in the Synthane pilot plant was subjected to operating conditions outside manufacturers' specifications. In some cases, these encounters were intentional and in other cases they resulted from insufficient data. All 106 of the test runs were terminated involuntarily. For the most part, the repetitive failures of plant materials and equipment originated from a combination of excessive solids overloading and corrosion/erosion caused by abnormal conditions of operation on fluid process streams. The extremes of these conditions were not anticipated nor were they taken into consideration in the design of the plant and in the selection of equipment and materials. Because of this situation, approximately half of the test run terminations were directly attributed to mechanical failures. Generally, for reasons given the maintenance, repair or replacement of failed equipment was not successful in eliminating or alleviating many failures until early 1978. Appropriate early planning can eliminate all these causes of failure in the future. Factors contributing to the difficulties in maintenance, repair, and replacement of failied materials and equipment are listed. In future construction, heavy reliance should be placed on engineering assessments of the equipment selection specifications, acceptance procedures, and the manner in which the equipment is installed, interconnected and operated. It is recommended that an effective and responsive data collection system on equipment specifications, operating conditions, performance, maintenance and repairs of critical equipment be incorporated as part of each pilot and demonstration plant effort. This step is essential to define required operating environments, equipment capabilities, failure histories, equipment and process interactions, as well as plant performance.

  13. Large Spectral Library Problem

    SciTech Connect

    Chilton, Lawrence K.; Walsh, Stephen J.

    2008-10-03

    Hyperspectral imaging produces a spectrum or vector at each image pixel. These spectra can be used to identify materials present in the image. In some cases, spectral libraries representing atmospheric chemicals or ground materials are available. The challenge is to determine if any of the library chemicals or materials exist in the hyperspectral image. The number of spectra in these libraries can be very large, far exceeding the number of spectral channels collected in the ¯eld. Suppose an image pixel contains a mixture of p spectra from the library. Is it possible to uniquely identify these p spectra? We address this question in this paper and refer to it as the Large Spectral Library (LSL) problem. We show how to determine if unique identi¯cation is possible for any given library. We also show that if p is small compared to the number of spectral channels, it is very likely that unique identi¯cation is possible. We show that unique identi¯cation becomes less likely as p increases.

  14. Smoothing of mixed complementarity problems

    SciTech Connect

    Gabriel, S.A.; More, J.J.

    1995-09-01

    The authors introduce a smoothing approach to the mixed complementarity problem, and study the limiting behavior of a path defined by approximate minimizers of a nonlinear least squares problem. The main result guarantees that, under a mild regularity condition, limit points of the iterates are solutions to the mixed complementarity problem. The analysis is applicable to a wide variety of algorithms suitable for large-scale mixed complementarity problems.

  15. Deterioration of Pracana Dam due to ASR. Main features and repair works

    SciTech Connect

    Matos, D.S.; Camelo, S.; Silva, H.S.; Pinho, J.S.

    1995-12-31

    Some of the Portuguese concrete dams show evidences of ASR. In majority the phenomena is still benign. However, in a few cases some significant deterioration of ASR type have malfunctions arose. In such cases deteriorations of ASR type have been detected while in the others the ASSR type prevail, depending on the type of aggregate. The paper reports the most important case of ASR in Portuguese concrete dams. Pracana dam is a buttress structures built in 1948-51, being the aggregates predominantly of quartzitic and metapellitic nature. Subsequently to the intense fracturing due to a quick concrete cooling during the first filling of the reservoir, high levels of expansion rates had been detected by means of monitoring system. After 8 years emptied reservoir, rehabilitation works took place in 1991-92 aiming at the concrete mass regeneration and the installation of an upstream face membrane, the improvement of spillway capacity and of the foundation performances. The behaviour of the dam as well as the performed tests (petrographic, mechanic, ultrasonic and expansibility ones) and repair works are described in the paper.

  16. Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling

    DOE PAGES [OSTI]

    Achar, Yathish Jagadheesh; Balogh, David; Neculai, Dante; Juhasz, Szilvia; Morocz, Monika; Gali, Himabindu; Dhe-Paganon, Sirano; Venclovas, Česlovas; Haracska, Lajos

    2015-09-08

    Defects in the ability to respond properly to an unrepaired DNA lesion blocking replication promote genomic instability and cancer. Human HLTF, implicated in error-free replication of damaged DNA and tumour suppression, exhibits a HIRAN domain, a RING domain, and a SWI/SNF domain facilitating DNA-binding, PCNA-polyubiquitin-ligase, and dsDNA-translocase activities, respectively. Here, we investigate the mechanism of HLTF action with emphasis on its HIRAN domain. We found that in cells HLTF promotes the filling-in of gaps left opposite damaged DNA during replication, and this postreplication repair function depends on its HIRAN domain. Our biochemical assays show that HIRAN domain mutant HLTF proteinsmore » retain their ubiquitin ligase, ATPase and dsDNA translocase activities but are impaired in binding to a model replication fork. These data and our structural study indicate that the HIRAN domain recruits HLTF to a stalled replication fork, and it also provides the direction for the movement of the dsDNA translocase motor domain for fork reversal. We suggest functional similarities between the HIRAN, the OB, the HARP2, and other domains found in certain motor proteins, which may explain why only a subset of DNA translocases can carry out fork reversal.« less

  17. Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling

    SciTech Connect

    Achar, Yathish Jagadheesh; Balogh, David; Neculai, Dante; Juhasz, Szilvia; Morocz, Monika; Gali, Himabindu; Dhe-Paganon, Sirano; Venclovas, Česlovas; Haracska, Lajos

    2015-09-08

    Defects in the ability to respond properly to an unrepaired DNA lesion blocking replication promote genomic instability and cancer. Human HLTF, implicated in error-free replication of damaged DNA and tumour suppression, exhibits a HIRAN domain, a RING domain, and a SWI/SNF domain facilitating DNA-binding, PCNA-polyubiquitin-ligase, and dsDNA-translocase activities, respectively. Here, we investigate the mechanism of HLTF action with emphasis on its HIRAN domain. We found that in cells HLTF promotes the filling-in of gaps left opposite damaged DNA during replication, and this postreplication repair function depends on its HIRAN domain. Our biochemical assays show that HIRAN domain mutant HLTF proteins retain their ubiquitin ligase, ATPase and dsDNA translocase activities but are impaired in binding to a model replication fork. These data and our structural study indicate that the HIRAN domain recruits HLTF to a stalled replication fork, and it also provides the direction for the movement of the dsDNA translocase motor domain for fork reversal. We suggest functional similarities between the HIRAN, the OB, the HARP2, and other domains found in certain motor proteins, which may explain why only a subset of DNA translocases can carry out fork reversal.

  18. Fractofusion mechanism

    SciTech Connect

    Yasui, K. . Dept. of Physics)

    1992-11-01

    In this paper, the fractofusion mechanism of cold fusion is investigated theoretically. The conditions necessary for fractofusion during the absorption of deuterium atoms by palladium specimens (the condition of so-called cold fusion experiments) is clarified, including crack generation at grain boundaries, the high orientation angle of grains, rapid crack formation, the increase of electrical resistance around a crack, the large width of cracks, and the generation of many cracks. The origin and quantity of the electrical field inside cracks in the conductor are also clarified. By the fractofusion mechanism, the experimental facts that neutron emissions are observed in bursts, that sometimes they coincide with the deformation of a palladium specimen, and that in many experiments excess neutrons were not observed are qualitatively explained. The upper limit of the total fractofusion yields during the absorption of deuterium atoms by palladium specimens are estimated.

  19. Development and validation of bonded composite doubler repairs for commercial aircraft.

    SciTech Connect

    Roach, Dennis Patrick; Rackow, Kirk A.

    2007-07-01

    A typical aircraft can experience over 2,000 fatigue cycles (cabin pressurizations) and even greater flight hours in a single year. An unavoidable by-product of aircraft use is that crack, impact, and corrosion flaws develop throughout the aircraft's skin and substructure elements. Economic barriers to the purchase of new aircraft have placed even greater demands on efficient and safe repair methods. The use of bonded composite doublers offers the airframe manufacturers and aircraft maintenance facilities a cost effective method to safely extend the lives of their aircraft. Instead of riveting multiple steel or aluminum plates to facilitate an aircraft repair, it is now possible to bond a single Boron-Epoxy composite doubler to the damaged structure. The FAA's Airworthiness Assurance Center at Sandia National Labs (AANC), Boeing, and Federal Express completed a pilot program to validate and introduce composite doubler repair technology to the U.S. commercial aircraft industry. This project focused on repair of DC-10 fuselage structure and its primary goal was to demonstrate routine use of this repair technology using niche applications that streamline the design-to-installation process. As composite doubler repairs gradually appear in the commercial aircraft arena, successful flight operation data is being accumulated. These commercial aircraft repairs are not only demonstrating the engineering and economic advantages of composite doubler technology but they are also establishing the ability of commercial maintenance depots to safely adopt this repair technique. This report presents the array of engineering activities that were completed in order to make this technology available for widespread commercial aircraft use. Focused laboratory testing was conducted to compliment the field data and to address specific issues regarding damage tolerance and flaw growth in composite doubler repairs. Fatigue and strength tests were performed on a simulated wing repair using a

  20. DNA repair of a single UV photoproduct in a designed nucleosome

    SciTech Connect

    Kosmoskil, Joseph V.; Ackerman, Eric J. ); Smerdon, Michael J.

    2001-08-28

    Eukaryotic DNA repair enzymes must interact with the architectural hierarchy of chromatin. The challenge of finding damaged DNA complexed with histone proteins in nucleosomes is complicated by the need to maintain local chromatin structures involved in regulating other DNA processing events. The heterogeneity of lesions induced by DNA-damaging agents has led us to design homogeneously damaged substrates to directly compare repair of naked DNA with that of nucleosomes. Here we report that nucleotide excision repair in Xenopus nuclear extracts can effectively repair a single UV radiation photoproduct located 5 bases from the dyad center of a positioned nucleosome, although the nucleosome is repaired at about half the rate at which the naked DNA fragment is. Extract repair within the nucleosome is > 50-fold more rapid than either enzymatic photoreversal or endonuclease cleavage of the lesion in vitro. Furthermore, nucleosome formation occurs (after repair) only on damaged naked DNA ( 165-bp fragments) during a 1-h incubation in these extracts, even in the presence of a large excess of undamaged DNA. This is an example of selective nucleosome assembly by Xenopus nuclear extracts on a short linear DNA fragment containing a DNA lesion.

  1. Metal inhibition of human alkylpurine-DNA-N-glycosylase activityin base excision repair

    SciTech Connect

    Wang, Ping; Guliaev, Anton B.; Hang, Bo

    2006-02-28

    Cadmium (Cd{sup 2+}), nickel (Ni{sup 2+}) and cobalt (Co{sup 2+}) are human and/or animal carcinogens. Zinc (Zn{sup 2+}) is not categorized as a carcinogen, and rather an essential element to humans. Metals were recently shown to inhibit DNA repair proteins that use metals for their function and/or structure. Here we report that the divalent ions Cd{sup 2+}, Ni{sup 2+}, and Zn{sup 2+} can inhibit the activity of a recombinant human N-methylpurine-DNA glycosylase (MPG) toward a deoxyoligonucleotide with ethenoadenine (var epsilonA). MPG removes a variety of toxic/mutagenic alkylated bases and does not require metal for its catalytic activity or structural integrity. At concentrations starting from 50 to 1000 {micro}M, both Cd{sup 2+} and Zn{sup 2+} showed metal-dependent inhibition of the MPG catalytic activity. Ni{sup 2+} also inhibited MPG, but to a lesser extent. Such an effect can be reversed with EDTA addition. In contrast, Co{sup 2+} and Mg{sup 2+} did not inhibit the MPG activity in the same dose range. Experiments using HeLa cell-free extracts demonstrated similar patterns of inactivation of the var epsilonA excision activity by the same metals. Binding of MPG to the substrate was not significantly affected by Cd{sup 2+}, Zn{sup 2+}, and Ni{sup 2+} at concentrations that show strong inhibition of the catalytic function, suggesting that the reduced catalytic activity is not due to altered MPG binding affinity to the substrate. Molecular dynamics (MD) simulations with Zn{sup 2+} showed that the MPG active site has a potential binding site for Zn{sup 2+}, formed by several catalytically important and conserved residues. Metal binding to such a site is expected to interfere with the catalytic mechanism of this protein. These data suggest that inhibition of MPG activity may contribute to metal genotoxicity and depressed repair of alkylation damage by metals in vivo.

  2. Emailed Comments of Elizabeth Chimento RE: Pepco Scheduled Line Repair Dec.

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    1-20, 2006 | Department of Energy Emailed Comments of Elizabeth Chimento RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Emailed Comments of Elizabeth Chimento RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Docket No. EO-05-01. Regarding the planned line outage, scheduled for Feb. 20 through Mar. 6, I am requesting that the residents near the plant be moved for the duration of the outage to protect their health. Emailed Comments of Elizabeth Chimento RE: Pepco Scheduled Line Repair Dec.

  3. About an Optimal Visiting Problem

    SciTech Connect

    Bagagiolo, Fabio Benetton, Michela

    2012-02-15

    In this paper we are concerned with the optimal control problem consisting in minimizing the time for reaching (visiting) a fixed number of target sets, in particular more than one target. Such a problem is of course reminiscent of the famous 'Traveling Salesman Problem' and brings all its computational difficulties. Our aim is to apply the dynamic programming technique in order to characterize the value function of the problem as the unique viscosity solution of a suitable Hamilton-Jacobi equation. We introduce some 'external' variables, one per target, which keep in memory whether the corresponding target is already visited or not, and we transform the visiting problem in a suitable Mayer problem. This fact allows us to overcome the lacking of the Dynamic Programming Principle for the originary problem. The external variables evolve with a hysteresis law and the Hamilton-Jacobi equation turns out to be discontinuous.

  4. ELEVATING MECHANISM

    DOEpatents

    Frederick, H.S.; Kinsella, M.A.

    1959-02-24

    An elevator is described, which is arranged for movement both in a horizontal and in a vertical direction so that the elevating mechanism may be employed for servicing equipment at separated points in a plant. In accordance with the present invention, the main elevator chassis is suspended from a monorail. The chassis, in turn supports a vertically moveable carriage, a sub- carriage vertically moveable on the carriage, and a turntable carried by the sub- carriage and moveable through an arc of 90 with the equipment attached thereto. In addition, the chassis supports all the means required to elevate or rotate the equipment.

  5. Tiny Terminators: New Micro-Robots Assemble, Repair Themselves and Are Surprisingly Strong

    Energy.gov [DOE]

    Tiny robots that can assemble and repair themselves? Watch a video of Argonne National Laboratory's micro-robots that easily perform tasks that can challenge other robots, including moving objects that are larger than themselves.

  6. Community-Minded Interns at Savannah River Site Help Area Residents in Need with Home Repairs

    Energy.gov [DOE]

    AIKEN, S.C. – More than two dozen college interns who worked at the Savannah River Site (SRS) this summer joined other volunteers and headed into area neighborhoods to help people in need with home repairs.

  7. Review of Maintenance and Repair Times for Components in Technological Facilities

    SciTech Connect

    L. C. Cadwallader

    2012-11-01

    This report is a compilation of some unique component repair time data and it also presents citations of more extensive reports where lists of repair times can be found. This collection of information should support analysts who seek to quantify maintainability and availability of high technology and nuclear energy production systems. While there are newer sources of repair time information, most, if not all, of the newer sources are proprietary and cannot be shared. This report offers data that, while older, is openly accessible and can serve as reasonable estimates of repair times, at least for initial studies. Some times were found for maintenance times in radiation environments, and some guidance for multiplicative factors to use to account for work in contamination areas.

  8. In situ repair of a failed compression fitting

    DOEpatents

    Wolbert, R.R.; Jandrasits, W.G.

    1985-08-05

    A method and apparatus for the in situ repair of a failed compression fitting is provided. Initially, a portion of a guide tube is inserted coaxially in the bore of the compression fitting and locked therein. A close fit dethreading device is then coaxially mounted on the guide tube to cut the threads from the fitting. Thereafter, the dethreading device and guide tube are removed and a new fitting is inserted onto the dethreaded fitting with the body of the new fitting overlaying the dethreaded portion. Finally, the main body of the new fitting is welded to the main body of the old fitting whereby a new threaded portion of the replacement fitting is precisely coaxial with the old threaded portion. If needed, a bushing is located on the dethreaded portion which is sized to fit snugly between the dethreaded portion and the new fitting. Preferably, the dethreading device includes a cutting tool which is moved incrementally in a radial direction whereby the threads are cut from the threaded portion of the failed fitting in increments.

  9. In situ repair of a failed compression fitting

    DOEpatents

    Wolbert, Ronald R.; Jandrasits, Walter G.

    1986-01-01

    A method and apparatus for the in situ repair of a failed compression fitg is provided. Initially, a portion of a guide tube is inserted coaxially in the bore of the compression fitting and locked therein. A close fit dethreading device is then coaxially mounted on the guide tube to cut the threads from the fitting. Thereafter, the dethreading device and guide tube are removed and a new fitting is inserted onto the dethreaded fitting with the body of the new fitting overlaying the dethreaded portion. Finally, the main body of the new fitting is welded to the main body of the old fitting whereby a new threaded portion of the replacement fitting is precisely coaxial with the old threaded portion. If needed, a bushing is located on the dethreaded portion which is sized to fit snugly between the dethreaded portion and the new fitting. Preferably, the dethreading device includes a cutting tool which is moved incrementally in a radial direction whereby the threads are cut from the threaded portion of the failed fitting in increments.

  10. Results of fracture mechanics analyses of the ederer cranes in the device assembly

    SciTech Connect

    Dalder, E.

    1996-08-01

    Fracture mechanics analyses were conducted on three critical locations on the lower flange of the load-beam of the Ederer 5 ton and 4 ton cranes in the D.A.F. Facility. Based on these results, it appears that: 1. Propagation of a 5 mm long flaw, previously undetected by non-destructive examination (NDE), to a length sufficient to cause structural failure of either flange, should not occur in at least 100 times the postulated operating scenarios for each crane; 2. Should each crane undergo annual inspection, any surface flaw with a length greater that 20 mm should be removed and repaired by qualified and approved repair procedures.

  11. Method to repair localized amplitude defects in a EUV lithography mask blank

    DOEpatents

    Stearns, Daniel G.; Sweeney, Donald W.; Mirkarimi, Paul B.; Chapman, Henry N.

    2005-11-22

    A method and apparatus are provided for the repair of an amplitude defect in a multilayer coating. A significant number of layers underneath the amplitude defect are undamaged. The repair technique restores the local reflectivity of the coating by physically removing the defect and leaving a wide, shallow crater that exposes the underlying intact layers. The particle, pit or scratch is first removed the remaining damaged region is etched away without disturbing the intact underlying layers.

  12. RESTORING A DAMAGED 16-YEAR -OLD INSULATING POLYMER CONCRETE DIKE OVERLAY: REPAIR MATERIALS AND TECHNOLOGIES.

    SciTech Connect

    SUGAMA,T.

    2007-01-01

    The objective of this program was to design and formulate organic polymer-based material systems suitable for repairing and restoring the overlay panels of insulating lightweight polymer concrete (ILPC) from the concrete floor and slope wall of a dike at KeySpan liquefied natural gas (LNG) facility in Greenpoint, Brooklyn, NY, just over sixteen years ago. It also included undertaking a small-scale field demonstration to ensure that the commercial repairing technologies were applicable to the designed and formulated materials.

  13. EA-2040: Strategic Petroleum Reserve Repair/Enhancement of Access to Remote

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Pipeline Valve Stations, West Hackberry; Calcasieu and Cameron Parishes, Louisiana | Department of Energy 40: Strategic Petroleum Reserve Repair/Enhancement of Access to Remote Pipeline Valve Stations, West Hackberry; Calcasieu and Cameron Parishes, Louisiana EA-2040: Strategic Petroleum Reserve Repair/Enhancement of Access to Remote Pipeline Valve Stations, West Hackberry; Calcasieu and Cameron Parishes, Louisiana Summary DOE is preparing an EA that evaluates the potential environmental

  14. Parallel Algebraic Multigrids for Structural mechanics

    SciTech Connect

    Brezina, M; Tong, C; Becker, R

    2004-05-11

    This paper presents the results of a comparison of three parallel algebraic multigrid (AMG) preconditioners for structural mechanics applications. In particular, they are interested in investigating both the scalability and robustness of the preconditioners. Numerical results are given for a range of structural mechanics problems with various degrees of difficulty.

  15. Further Evolution of Composite Doubler Aircraft Repairs Through a Focus on Niche Applications

    SciTech Connect

    ROACH,DENNIS P.

    2000-07-15

    The number of commercial airframes exceeding twenty years of service continues to grow. A typical aircraft can experience over 2,000 fatigue cycles (cabin pressurizations) and even greater flight hours in a single year. An unavoidable by-product of aircraft use is that crack and corrosion flaws develop throughout the aircraft's skin and substructure elements. Economic barriers to the purchase of new aircraft have created an aging aircraft fleet and placed even greater demands on efficient and safe repair methods. The use of bonded composite doublers offers the airframe manufacturers and aircraft maintenance facilities a cost effective method to safety extend the lives of their aircraft. Instead of riveting multiple steel or aluminum plates to facilitate an aircraft repair, it is now possible to bond a single Boron-Epoxy composite doubler to the damaged structure. The FAA's Airworthiness Assurance Center at Sandia National Labs (AANC) is conducting a program with Boeing and Federal Express to validate and introduce composite doubler repair technology to the US commercial aircraft industry. This project focuses on repair of DC-10 structure and builds on the foundation of the successful L-1011 door corner repair that was completed by the AANC, Lockheed-Martin, and Delta Air Lines. The L-1011 composite doubler repair was installed in 1997 and has not developed any flaws in over three years of service, As a follow-on effort, this DC-1O repair program investigated design, analysis, performance (durability, flaw containment, reliability), installation, and nondestructive inspection issues. Current activities are demonstrating regular use of composite doubler repairs on commercial aircraft. The primary goal of this program is to move the technology into niche applications and to streamline the design-to-installation process. Using the data accumulated to date, the team has designed, analyzed, and developed inspection techniques for an array of composite doubler repairs

  16. Relocation and repair of the National Geotechnical Centrifuge. Final report

    SciTech Connect

    Cheney, J.A.

    1994-10-01

    In January of 1984, the large geotechnical centrifuge located at NASA Ames Research Center, was in the first stages of operational checkout when the main thrust bearing of the large D.C. drive motor failed. After many months of investigation and proposals for repair of the facility, it became evident that it would be far more advantageous to the engineering community to remove those components of the centrifuge that were undamaged to the Davis campus and replace the drive system completely. The large centrifuge had cost over 2 million dollars to build, and it would have been irresponsible to simply scrap it. Recognizing this fact, funds were solicited and received from various sources, and Beam Engineering Inc. was contracted to design and construct the centrifuge at its new location. The University of California contributed a quarter of a million dollars and Tyndall Air Force Base, through Los Alamos National Laboratory, contributed $140,000. There were funds also contributed by LANL, LLNL, US Navy and NSF. The first stage in the phased development of the newly located centrifuge is nearing completion, which prompts the writing of this report. By the time that this report reaches the reader the first runs of the centrifuge will have been completed. The present report describes the present capability of the centrifuge and the plans for upgrading as time goes on. Several pilot studies were carried out. The experiments involved (1) the effects of nearby explosions on buried thin walled containers and (2) the advection and dispersion of toxic waste water through soils.

  17. Mechanical Design

    SciTech Connect

    Shook, Richard; /Marquette U. /SLAC

    2010-08-25

    The particle beam of the SXR (soft x-ray) beam line in the LCLS (Linac Coherent Light Source) has a high intensity in order to penetrate through samples at the atomic level. However, the intensity is so high that many experiments fail because of severe damage. To correct this issue, attenuators are put into the beam line to reduce this intensity to a level suitable for experimentation. Attenuation is defined as 'the gradual loss in intensity of any flux through a medium' by [1]. It is found that Beryllium and Boron Carbide can survive the intensity of the beam. At very thin films, both of these materials work very well as filters for reducing the beam intensity. Using a total of 12 filters, the first 9 being made of Beryllium and the rest made of Boron Carbide, the beam's energy range of photons can be attenuated between 800 eV and 9000 eV. The design of the filters allows attenuation for different beam intensities so that experiments can obtain different intensities from the beam if desired. The step of attenuation varies, but is relative to the thickness of the filter as a power function of 2. A relationship for this is f(n) = x{sub 0}2{sup n} where n is the step of attenuation desired and x{sub 0} is the initial thickness of the material. To allow for this desired variation, a mechanism must be designed within the test chamber. This is visualized using a 3D computer aided design modeling tool known as Solid Edge.

  18. DNA repair decline during mouse spermiogenesis results in the accumulation of heritable DNA damage

    SciTech Connect

    Marchetti, Francesco; Marchetti, Francesco; Wryobek, Andrew J

    2008-02-21

    The post-meiotic phase of mouse spermatogenesis (spermiogenesis) is very sensitive to the genomic effects of environmental mutagens because as male germ cells form mature sperm they progressively lose the ability to repair DNA damage. We hypothesized that repeated exposures to mutagens during this repair-deficient phase result in the accumulation of heritable genomic damage in mouse sperm that leads to chromosomal aberrations in zygotes after fertilization. We used a combination of single or fractionated exposures to diepoxybutane (DEB), a component of tobacco smoke, to investigate how differential DNA repair efficiencies during the three weeks of spermiogenesis affected the accumulation of DEB-induced heritable damage in early spermatids (21-15 days before fertilization, dbf), late spermatids (14-8 dbf) and sperm (7- 1 dbf). Analysis of chromosomalaberrations in zygotic metaphases using PAINT/DAPI showed that late spermatids and sperm are unable to repair DEB-induced DNA damage as demonstrated by significant increases (P<0.001) in the frequencies of zygotes with chromosomal aberrations. Comparisons between single and fractionated exposures suggested that the DNA repair-deficient window during late spermiogenesis may be less than two weeks in the mouse and that during this repair-deficient window there is accumulation of DNA damage in sperm. Finally, the dose-response study in sperm indicated a linear response for both single and repeated exposures. These findings show that the differential DNA repair capacity of post-meioitic male germ cells has a major impact on the risk of paternally transmitted heritable damage and suggest that chronic exposures that may occur in the weeks prior to fertilization because of occupational or lifestyle factors (i.e, smoking) can lead to an accumulation of genetic damage in sperm and result in heritable chromosomal aberrations of paternal origin.

  19. DNA Repair Decline During Mouse Spermiogenesis Results in the Accumulation of Heritable DNA Damage

    SciTech Connect

    Marchetti, Francesco; Marchetti, Francesco; Wyrobek, Andrew J.

    2007-12-01

    The post-meiotic phase of mouse spermatogenesis (spermiogenesis) is very sensitive to the genomic effects of environmental mutagens because as male germ cells form mature sperm they progressively lose the ability to repair DNA damage. We hypothesized that repeated exposures to mutagens during this repair-deficient phase result in the accumulation of heritable genomic damage in mouse sperm that leads to chromosomal aberrations in zygotes after fertilization. We used a combination of single or fractionated exposures to diepoxybutane (DEB), a component of tobacco smoke, to investigate how differential DNA repair efficiencies during the three weeks of spermiogenesis affected the accumulation of DEB-induced heritable damage in early spermatids (21-15 days before fertilization, dbf), late spermatids (14-8 dbf) and sperm (7-1 dbf). Analysis of chromosomal aberrations in zygotic metaphases using PAINT/DAPI showed that late spermatids and sperm are unable to repair DEB-induced DNA damage as demonstrated by significant increases (P<0.001) in the frequencies of zygotes with chromosomal aberrations. Comparisons between single and fractionated exposures suggested that the DNA repair-deficient window during late spermiogenesis may be less than two weeks in the mouse and that during this repair-deficient window there is accumulation of DNA damage in sperm. Finally, the dose-response study in sperm indicated a linear response for both single and repeated exposures. These findings show that the differential DNA repair capacity of post-meioitic male germ cells has a major impact on the risk of paternally transmitted heritable damage and suggest that chronic exposures that may occur in the weeks prior to fertilization because of occupational or lifestyle factors (i.e, smoking) can lead to an accumulation of genetic damage in sperm and result in heritable chromosomal aberrations of paternal origin.

  20. Problems in nonlinear resistive MHD

    SciTech Connect

    Turnbull, A.D.; Strait, E.J.; La Haye, R.J.; Chu, M.S.; Miller, R.L.

    1998-12-31

    Two experimentally relevant problems can relatively easily be tackled by nonlinear MHD codes. Both problems require plasma rotation in addition to the nonlinear mode coupling and full geometry already incorporated into the codes, but no additional physics seems to be crucial. These problems discussed here are: (1) nonlinear coupling and interaction of multiple MHD modes near the B limit and (2) nonlinear coupling of the m/n = 1/1 sawtooth mode with higher n gongs and development of seed islands outside q = 1.

  1. Encapsulation of the UV-DNA repair enzyme T4 endonuclease V in liposomes and delivery to human cells

    SciTech Connect

    Ceccoli, J.; Rosales, N.; Tsimis, J.; Yarosh, D.B. )

    1989-08-01

    T4 endonuclease V, a pyrimidine-dimer-specific DNA repair enzyme, was encapsulated in liposomes under mild conditions. The encapsulated enzyme was active, and when applied to ultraviolet (UV)-irradiated human cells in culture, the liposomes increased incision of UV-irradiated cellular DNA, enhanced DNA repair replication, and enhanced survival of UV-irradiated cells. This method is a first step in a new approach for topical application of DNA repair enzymes to human skin to prevent skin cancer.

  2. Problem

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    But what if the batteries had the ability to recharge themselves? What if they were covered by a thin photovoltaic (PV) film that could harvest energy from the sun? Just as on ...

  3. Problem

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    commercially available polymers, dissolving them in common solvents at a normal temperature and pressure, and then using a simple spin, dip, or spray technique to coat the surface. ...

  4. Problem

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    energy solutions, Sandia and Princeton Power Systems have teamed up to develop the Demand Response Inverter (DRI). Innovative Edge The DRI is a power flow control system...

  5. Problem

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    They can reduce the size and weight of existing next-generation smart grid power electronics systems, allowing greater application in such areas as weapons systems and pulsed...

  6. Heavy Mobile Equipment Mechanic (One Mechanic Shop)

    Energy.gov [DOE]

    Join the Bonneville Power Administration (BPA) for a challenging and rewarding career, while working, living, and playing in the Pacific Northwest. The Heavy Mobile Equipment Mechanic (One Mechanic...

  7. Surrogate Guderley Test Problem Definition

    SciTech Connect

    Ramsey, Scott D.; Shashkov, Mikhail J.

    2012-07-06

    The surrogate Guderley problem (SGP) is a 'spherical shock tube' (or 'spherical driven implosion') designed to ease the notoriously subtle initialization of the true Guderley problem, while still maintaining a high degree of fidelity. In this problem (similar to the Guderley problem), an infinitely strong shock wave forms and converges in one-dimensional (1D) cylindrical or spherical symmetry through a polytropic gas with arbitrary adiabatic index {gamma}, uniform density {rho}{sub 0}, zero velocity, and negligible pre-shock pressure and specific internal energy (SIE). This shock proceeds to focus on the point or axis of symmetry at r = 0 (resulting in ostensibly infinite pressure, velocity, etc.) and reflect back out into the incoming perturbed gas.

  8. Working report and instruction for repairing of three peaces of wings from a 30 kW Riisagermill

    SciTech Connect

    Ethelfeld, J.; Jensen, F.; Kjoller, J.; Lystrup, A.

    1980-01-01

    This report is made to give the owners of Riisager windmills an instruction to make service and repair of the fiber glass wings.

  9. SEACAS Theory Manuals: Part II. Nonlinear Continuum Mechanics

    SciTech Connect

    Attaway, S.W.; Laursen, T.A.; Zadoks, R.I.

    1998-09-01

    This report summarizes the key continuum mechanics concepts required for the systematic prescription and numerical solution of finite deformation solid mechanics problems. Topics surveyed include measures of deformation appropriate for media undergoing large deformations, stress measures appropriate for such problems, balance laws and their role in nonlinear continuum mechanics, the role of frame indifference in description of large deformation response, and the extension of these theories to encompass two dimensional idealizations, structural idealizations, and rigid body behavior. There are three companion reports that describe the problem formulation, constitutive modeling, and finite element technology for nonlinear continuum mechanics systems.

  10. Automatic coke oven heating control system at Burns Harbor for normal and repair operation

    SciTech Connect

    Battle, E.T.; Chen, K.L.

    1997-12-31

    An automatic heating control system for coke oven batteries was developed in 1985 for the Burns Harbor No. 1 battery and reported in the 1989 Ironmaking Conference Proceedings. The original system was designed to maintain a target coke temperature at a given production level under normal operating conditions. Since 1989, enhancements have been made to this control system so that it can also control the battery heating when the battery is under repair. The new control system has improved heating control capability because it adjusts the heat input to the battery in response to anticipated changes in the production schedule. During a recent repair of this 82 oven battery, the pushing schedule changed from 102 ovens/day to 88 ovens/day, then back to 102 ovens/day, then to 107 ovens/day. During this repair, the control system was able to maintain the coke temperature average standard deviation at 44 F, with a maximum 75 F.

  11. Evaluation of bisphenol E cyanate ester for the resin-injection repair of advanced composites

    SciTech Connect

    Lio, Wilber Yaote

    2009-12-01

    This thesis is a compilation of a general introduction and literature review that ties together the subsequent chapters which consist of two journal articles that have yet to be submitted for publication. The overall topic relates to the evaluation and application of a new class of cyanate ester resin with unique properties that lend it applicable to use as a resin for injection repair of high glass transition temperature polymer matrix composites. The first article (Chapter 2) details the evaluation and optimization of adhesive properties of this cyanate ester and alumina nanocomposites under different conditions. The second article (Chapter 3) describes the development and evaluation of an injection repair system for repairing delaminations in polymer matrix composites.

  12. Alternatives Analysis Amchitka Island Mud Pit Cap Repair, Amchitka, Alaska January 2016

    SciTech Connect

    Darr, Paul S.

    2016-01-01

    The U.S. Department of Energy (DOE) Office of Legacy Management (LM) manages the Nevada Offsites program, which includes a series of reclaimed drilling mud impoundments on Amchitka Island, Alaska (Figure 1). Navarro Research and Engineering, Inc. is the Legacy Management Support contractor (the Contractor) for LM. The Contractor has procured Tetra Tech, Inc. to provide engineering support to the Amchitka mud pit reclamation project. The mud pit caps were damaged during a 7.9-magnitude earthquake that occurred in 2014. The goals of the current project are to investigate conditions at the mud pit impoundments, identify feasible alternatives for repair of the cover systems and the contents, and estimate relative costs of repair alternatives. This report presents descriptions of the sites and past investigations, existing conditions, summaries of various repair/mitigation alternatives, and direct, unburdened, order-of-magnitude (-15% to +50%) associated costs.

  13. A survey of repair practices for nuclear power plant containment metallic pressure boundaries

    SciTech Connect

    Oland, C.B.; Naus, D.J.

    1998-05-01

    The Nuclear Regulatory Commission has initiated a program at the Oak Ridge National Laboratory to provide assistance in their assessment of the effects of potential degradation on the structural integrity and leaktightness of metal containment vessels and steel liners of concrete containments in nuclear power plants. One of the program objectives is to identify repair practices for restoring metallic containment pressure boundary components that have been damaged or degraded in service. This report presents issues associated with inservice condition assessments and continued service evaluations and identifies the rules and requirements for the repair and replacement of nonconforming containment pressure boundary components by welding or metal removal. Discussion topics include base and welding materials, welding procedure and performance qualifications, inspection techniques, testing methods, acceptance criteria, and documentation requirements necessary for making acceptable repairs and replacements so that the plant can be returned to a safe operating condition.

  14. Operating experience review of service water system problems

    SciTech Connect

    Lam, P.

    1989-01-01

    In a recent paper, selected results of a comprehensive review and evaluation of service water system problems conducted by the Office for Analysis and Evaluation of Operational Data (AEOD) of the US Nuclear Regulatory Commission (NRC) were presented. The results of this review and evaluation indicated that service water system problems have significant safety implications. These system problems are attributable to a great variety of causes and have adverse impacts on a large number of safety-related systems and components. To provide additional feedback of operating experience, this paper presents an overview of the dominant mechanisms leading to service water system degradations and failures. The failures and degradations of service water systems observed in the 276 operating events are grouped into six general categories. The six general categories are (1) fouling due to various mechanisms, (2) single-failure and other design deficiencies, (3) flooding, (4) equipment failures, (5) personnel and procedural errors, and (6) seismic deficiencies.

  15. Challenge problems for artificial intelligence

    SciTech Connect

    Selman, B.; Brooks, R.A.; Dean, T.

    1996-12-31

    AI textbooks and papers of ten discuss the big questions, such as {open_quotes}how to reason with uncertainty{close_quotes}, {open_quotes}how to reason efficiently{close_quotes}, or {open_quotes}how to improve performance through learning.{close_quotes} It is more difficult, however, to find descriptions of concrete problems or challenges that are still ambitious and interesting, yet not so open-ended. The goal of this panel is to formulate a set of such challenge problems for the field. Each panelist was asked to formulate one or more challenges. The emphasis is on problems for which there is a good chance that they will be resolved within the next five to ten years.

  16. Remote reactor repair: GTA (gas tungsten Arc) weld cracking caused by entrapped helium

    SciTech Connect

    Kanne, W.R. Jr.

    1988-01-01

    A repair patch was welded to the wall of a nuclear reactor tank using remotely controlled thirty-foot long robot arms. Further repair was halted when gas tungsten arc (GTA) welds joining type 304L stainless steel patches to the 304 stainless steel wall developed toe cracks in the heat-affected zone (HAZ). The role of helium in cracking was investigated using material with entrapped helium from tritium decay. As a result of this investigation, and of an extensive array of diagnostic tests performed on reactor tank wall material, helium embrittlement was shown to be the cause of the toe cracks.

  17. Bosh repairs No. 3 blast furnace, Edgar Thomson Plant Mon Valley Works

    SciTech Connect

    Stoupis, M.G.

    1993-01-01

    The paper describes in detail the steps taken from quenching to dry out of the furnace to repair the bosh area of the No.3 blast furnace. Inspection of the area revealed that there was no brick anywhere in the bosh. Brick in the tuyere breast area had been peeled back to reveal the steel plate, and descaling revealed 14 pipes fully exposed. None were leaking, but one seemed badly deteriorated. Conventional repairs could not take place before the scheduled blow-in. Installation of coolers were instead tried.

  18. Computational Structural Mechanics

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    load-2 TRACC RESEARCH Computational Fluid Dynamics Computational Structural Mechanics Transportation Systems Modeling Computational Structural Mechanics Overview of CSM ...

  19. Current problems in plasma spray processing

    SciTech Connect

    Berndt, C.C.; Brindley, W.; Goland, A.N.; Herman, H.; Houck, D.L.; Jones, K.; Miller, R.A.; Neiser, R.; Riggs, W.; Sampath, S.; Smith, M.; Spanne, P.

    1991-12-31

    This detailed report summarizes 8 contributions from a thermal spray conference that was held in late 1991 at Brookhaven National Laboratory (Upton, Long Island, NY, USA). The subject of ``Plasma Spray Processing`` is presented under subject headings of Plasma-particle interactions, Deposit formation dynamics, Thermal properties of thermal barrier coatings, Mechanical properties of coatings, Feed stock materials, Porosity: An integrated approach, Manufacture of intermetallic coatings, and Synchrotron x-ray microtomographic methods for thermal spray materials. Each section is intended to present a concise statement of a specific practical and/or scientific problem, then describe current work that is being performed to investigate this area, and finally to suggest areas of research that may be fertile for future activity.

  20. Current problems in plasma spray processing

    SciTech Connect

    Berndt, C.C.; Brindley, W.; Goland, A.N.; Herman, H.; Houck, D.L.; Jones, K.; Miller, R.A.; Neiser, R.; Riggs, W.; Sampath, S.; Smith, M.; Spanne, P. . Thermal Spray Lab.)

    1991-01-01

    This detailed report summarizes 8 contributions from a thermal spray conference that was held in late 1991 at Brookhaven National Laboratory (Upton, Long Island, NY, USA). The subject of Plasma Spray Processing'' is presented under subject headings of Plasma-particle interactions, Deposit formation dynamics, Thermal properties of thermal barrier coatings, Mechanical properties of coatings, Feed stock materials, Porosity: An integrated approach, Manufacture of intermetallic coatings, and Synchrotron x-ray microtomographic methods for thermal spray materials. Each section is intended to present a concise statement of a specific practical and/or scientific problem, then describe current work that is being performed to investigate this area, and finally to suggest areas of research that may be fertile for future activity.

  1. Sour landfill gas problem solved

    SciTech Connect

    Nagl, G.; Cantrall, R.

    1996-05-01

    In Broward County, Fla., near Pompano Beach, Waste Management of North America (WMNA, a subsidiary of WMX Technologies, Oak Brook, IL) operates the Central Sanitary Landfill and Recycling Center, which includes the country`s largest landfill gas-to-energy plant. The landfill consists of three collection sites: one site is closed, one is currently receiving garbage, and one will open in the future. Approximately 9 million standard cubic feet (scf) per day of landfill gas is collected from approximately 300 wells spread over the 250-acre landfill. With a dramatic increase of sulfur-containing waste coming to a South Florida landfill following Hurricane Andrew, odors related to hydrogen sulfide became a serious problem. However, in a matter of weeks, an innovative desulfurization unit helped calm the landfill operator`s fears. These very high H{sub 2}S concentrations caused severe odor problems in the surrounding residential area, corrosion problems in the compressors, and sulfur dioxide (SO{sub 2}) emission problems in the exhaust gas from the turbine generators.

  2. Substation automation problems and possibilities

    SciTech Connect

    Smith, H.L.

    1996-10-01

    The evolutionary growth in the use and application of microprocessors in substations has brought the industry to the point of considering integrated substation protection, control, and monitoring systems. An integrated system holds the promise of greatly reducing the design, documentation, and implementation cost for the substation control, protection, and monitoring systems. This article examines the technical development path and the present implementation problems.

  3. Hot repair of ceramic burner on hot blast stoves at USS/Kobe`s {number_sign}3 blast furnace

    SciTech Connect

    Bernarding, T.F.; Chemorov, M.; Shimono, S.; Phillips, G.R.

    1997-12-31

    During the 1992 reline of the No. 3 blast furnace, three new stoves were constructed. The design of the stoves, equipped with internal ceramic burners, was for providing a hot blast temperature of 2,000 F at a wind rate of 140,000 SCFM. After 3 years the performance had deteriorated so the burners were cleaned. When a second cleaning did not improve the performance of No. 3 blast furnace, it was decided to repair the refractory while still hot. The paper describes the hot repair procedures, taking a stove off for repairs, maintenance heat up during repairs, two stove operation, stove commissioning, repair of a ceramic burner, and wet gas prevention.

  4. CrowdPhase: crowdsourcing the phase problem

    SciTech Connect

    Jorda, Julien; Sawaya, Michael R.; Yeates, Todd O.

    2014-06-01

    The idea of attacking the phase problem by crowdsourcing is introduced. Using an interactive, multi-player, web-based system, participants work simultaneously to select phase sets that correspond to better electron-density maps in order to solve low-resolution phasing problems. The human mind innately excels at some complex tasks that are difficult to solve using computers alone. For complex problems amenable to parallelization, strategies can be developed to exploit human intelligence in a collective form: such approaches are sometimes referred to as ‘crowdsourcing’. Here, a first attempt at a crowdsourced approach for low-resolution ab initio phasing in macromolecular crystallography is proposed. A collaborative online game named CrowdPhase was designed, which relies on a human-powered genetic algorithm, where players control the selection mechanism during the evolutionary process. The algorithm starts from a population of ‘individuals’, each with a random genetic makeup, in this case a map prepared from a random set of phases, and tries to cause the population to evolve towards individuals with better phases based on Darwinian survival of the fittest. Players apply their pattern-recognition capabilities to evaluate the electron-density maps generated from these sets of phases and to select the fittest individuals. A user-friendly interface, a training stage and a competitive scoring system foster a network of well trained players who can guide the genetic algorithm towards better solutions from generation to generation via gameplay. CrowdPhase was applied to two synthetic low-resolution phasing puzzles and it was shown that players could successfully obtain phase sets in the 30° phase error range and corresponding molecular envelopes showing agreement with the low-resolution models. The successful preliminary studies suggest that with further development the crowdsourcing approach could fill a gap in current crystallographic methods by making it

  5. Multilayer sulfur-resistant composite metal membranes and methods of making and repairing the same

    DOEpatents

    Way, J. Douglas; Hatlevik, Oyvind

    2014-07-15

    The invention relates to thin, hydrogen-permeable, sulfur-resistant membranes formed from multi-layers of palladium or palladium-alloy coatings on porous, ceramic or metal supports, methods of making these membranes, methods of repairing layers of these membranes and devices that incorporate these membranes.

  6. Final Report for LDRD Project on Rapid Problem Setup for Mesh-Based Simulation (Rapsodi)

    SciTech Connect

    Brown, D L; Henshaw, W; Petersson, N A; Fast, P; Chand, K

    2003-02-07

    Under LLNL Exploratory Research LDRD funding, the Rapsodi project developed rapid setup technology for computational physics and engineering problems that require computational representations of complex geometry. Many simulation projects at LLNL involve the solution of partial differential equations in complex 3-D geometries. A significant bottleneck in carrying out these simulations arises in converting some specification of a geometry, such as a computer-aided design (CAD) drawing to a computationally appropriate 3-D mesh that can be used for simulation and analysis. Even using state-of-the-art mesh generation software, this problem setup step typically has required weeks or months, which is often much longer than required to carry out the computational simulation itself. The Rapsodi project built computational tools and designed algorithms that help to significantly reduce this setup time to less than a day for many realistic problems. The project targeted rapid setup technology for computational physics and engineering problems that use mixed-element unstructured meshes, overset meshes or Cartesian-embedded boundary (EB) meshes to represent complex geometry. It also built tools that aid in constructing computational representations of geometry for problems that do not require a mesh. While completely automatic mesh generation is extremely difficult, the amount of manual labor required can be significantly reduced. By developing novel, automated, component-based mesh construction procedures and automated CAD geometry repair and cleanup tools, Rapsodi has significantly reduced the amount of hand crafting required to generate geometry and meshes for scientific simulation codes.

  7. Retrofitting and the mu Problem

    SciTech Connect

    Green, Daniel; Weigand, Timo; /SLAC /Stanford U., Phys. Dept.

    2010-08-26

    One of the challenges of supersymmetry (SUSY) breaking and mediation is generating a {mu} term consistent with the requirements of electro-weak symmetry breaking. The most common approach to the problem is to generate the {mu} term through a SUSY breaking F-term. Often these models produce unacceptably large B{mu} terms as a result. We will present an alternate approach, where the {mu} term is generated directly by non-perturtative effects. The same non-perturbative effect will also retrofit the model of SUSY breaking in such a way that {mu} is at the same scale as masses of the Standard Model superpartners. Because the {mu} term is not directly generated by SUSY breaking effects, there is no associated B{mu} problem. These results are demonstrated in a toy model where a stringy instanton generates {mu}.

  8. SEACAS Theory Manuals: Part 1. Problem Formulation in Nonlinear Solid Mechancis

    SciTech Connect

    Attaway, S.W.; Laursen, T.A.; Zadoks, R.I.

    1998-08-01

    This report gives an introduction to the basic concepts and principles involved in the formulation of nonlinear problems in solid mechanics. By way of motivation, the discussion begins with a survey of some of the important sources of nonlinearity in solid mechanics applications, using wherever possible simple one dimensional idealizations to demonstrate the physical concepts. This discussion is then generalized by presenting generic statements of initial/boundary value problems in solid mechanics, using linear elasticity as a template and encompassing such ideas as strong and weak forms of boundary value problems, boundary and initial conditions, and dynamic and quasistatic idealizations. The notational framework used for the linearized problem is then extended to account for finite deformation of possibly inelastic solids, providing the context for the descriptions of nonlinear continuum mechanics, constitutive modeling, and finite element technology given in three companion reports.

  9. Solving the Dark Matter Problem

    ScienceCinema

    Baltz, Ted

    2016-07-12

    Cosmological observations have firmly established that the majority of matter in the universe is of an unknown type, called 'dark matter'. A compelling hypothesis is that the dark matter consists of weakly interacting massive particles (WIMPs) in the mass range around 100 GeV. If the WIMP hypothesis is correct, such particles could be created and studied at accelerators. Furthermore they could be directly detected as the primary component of our galaxy. Solving the dark matter problem requires that the connection be made between the two. We describe some theoretical and experimental avenues that might lead to this connection.

  10. Common Air Conditioner Problems | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Common Air Conditioner Problems Common Air Conditioner Problems A refrigerant leak is one common air conditioning problem. | Photo courtesy of ©iStockphoto/BanksPhotos. A refrigerant leak is one common air conditioning problem. | Photo courtesy of ©iStockphoto/BanksPhotos. One of the most common air conditioning problems is improper operation. If your air conditioner is on, be sure to close your home's windows and outside doors. For room air conditioners, isolate the room or a group of

  11. Cosmological moduli problem in large volume scenario and thermal inflation

    SciTech Connect

    Choi, Kiwoon; Park, Wan-Il; Shin, Chang Sub E-mail: wipark@kias.re.kr

    2013-03-01

    We show that in a large volume scenario of type IIB string or F-theory compactifications, single thermal inflation provides only a partial solution to the cosmological problem of the light volume modulus. We then clarify the conditions for double thermal inflation, being a simple extension of the usual single thermal inflation scenario, to solve the cosmological moduli problem in the case of relatively light moduli masses. Using a specific example, we demonstrate that double thermal inflation can be realized in large volume scenario in a natural manner, and the problem of the light volume modulus can be solved for the whole relevant mass range. We also find that right amount of baryon asymmetry and dark matter can be obtained via a late-time Affleck-Dine mechanism and the decays of the visible sector NLSP to flatino LSP.

  12. Tensile strengths of problem shales and clays. Master's thesis

    SciTech Connect

    Rechner, F.J.

    1990-01-01

    The greatest single expense faced by oil companies involved in the exploration for crude oil is that of drilling wells. The most abundant rock drilled is shale. Some of these shales cause wellbore stability problems during the drilling process. These can range from slow rate of penetration and high torque up to stuck pipe and hole abandonment. The mechanical integrity of the shale must be known when the shalers are subjected to drilling fluids to develop an effective drilling plan.

  13. Endovascular Repair of a Ruptured Mycotic Aneurysm of the Common Iliac Artery

    SciTech Connect

    Mofidi, R. Bhat, R.; Nagy, J.; Griffiths, G. D.; Chakraverty, S.

    2007-09-15

    This report describes the case of a ruptured mycotic aneurysm of the left common iliac artery, successfully treated with endovascular stent-grafting. A 64-year-old woman underwent diagnostic coronary angiography complicated by an infected hematoma of the left groin. Seven days later, she developed methicillin-resistant Staphylococcus aureus septicemia and CT scan evidence of perivascular inflammation around the left common iliac artery. This was followed by rupture of a mycotic aneurysm of the left common iliac artery. The lesion was successfully treated with a stent-graft and prolonged antibiotic therapy, and the patient remains free of infection 10 months later. Accumulating evidence suggests that endovascular repair can be used safely for the repair of ruptured infected aneurysms.

  14. Repair of localized defects in multilayer-coated reticle blanks for extreme ultraviolet lithography

    DOEpatents

    Stearns, Daniel G.; Sweeney, Donald W.; Mirkarimi, Paul B.

    2004-11-23

    A method is provided for repairing defects in a multilayer coating layered onto a reticle blank used in an extreme ultraviolet lithography (EUVL) system. Using high lateral spatial resolution, energy is deposited in the multilayer coating in the vicinity of the defect. This can be accomplished using a focused electron beam, focused ion beam or a focused electromagnetic radiation. The absorbed energy will cause a structural modification of the film, producing a localized change in the film thickness. The change in film thickness can be controlled with sub-nanometer accuracy by adjusting the energy dose. The lateral spatial resolution of the thickness modification is controlled by the localization of the energy deposition. The film thickness is adjusted locally to correct the perturbation of the reflected field. For example, when the structural modification is a localized film contraction, the repair of a defect consists of flattening a mound or spreading out the sides of a depression.

  15. Subterranean barriers, methods, and apparatuses for forming, inspecting, selectively heating, and repairing same

    DOEpatents

    Nickelson, Reva A.; Sloan, Paul A.; Richardson, John G.; Walsh, Stephanie; Kostelnik, Kevin M.

    2009-04-07

    A subterranean barrier and method for forming same are disclosed, the barrier including a plurality of casing strings wherein at least one casing string of the plurality of casing strings may be affixed to at least another adjacent casing string of the plurality of casing strings through at least one weld, at least one adhesive joint, or both. A method and system for nondestructively inspecting a subterranean barrier is disclosed. For instance, a radiographic signal may be emitted from within a casing string toward an adjacent casing string and the radiographic signal may be detected from within the adjacent casing string. A method of repairing a barrier including removing at least a portion of a casing string and welding a repair element within the casing string is disclosed. A method of selectively heating at least one casing string forming at least a portion of a subterranean barrier is disclosed.

  16. Weld Repair of a Stamped Pressure Vessel in a Radiologically Controlled Zone

    SciTech Connect

    Cannell, Gary L.; Huth, Ralph J.; Hallum, Randall T.

    2013-08-26

    In September 2012 an ASME B&PVC Section VIII stamped pressure vessel located at the DOE Hanford Site Effluent Treatment Facility (ETF) developed a through-wall leak. The vessel, a steam/brine heat exchanger, operated in a radiologically controlled zone (by the CH2MHill PRC or CHPRC), had been in service for approximately 17 years. The heat exchanger is part of a single train evaporator process and its failure caused the entire system to be shut down, significantly impacting facility operations. This paper describes the activities associated with failure characterization, technical decision making/planning for repair by welding, logistical challenges associated with performing work in a radiologically controlled zone, performing the repair, and administrative considerations related to ASME code requirements.

  17. Quantum simulations of physics problems

    SciTech Connect

    Somma, R. D.; Ortiz, G.; Knill, E. H.; Gubernatis, J. E.

    2003-01-01

    If a large Quantum Computer (QC) existed today, what type of physical problems could we efficiently simulate on it that we could not efficiently simulate on a classical Turing machine? In this paper we argue that a QC could solve some relevant physical 'questions' more efficiently. The existence of one-to-one mappings between different algebras of observables or between different Hilbert spaces allow us to represent and imitate any physical system by any other one (e.g., a bosonic system by a spin-1/2 system). We explain how these mappings can be performed, and we show quantum networks useful for the efficient evaluation of some physical properties, such as correlation functions and energy spectra.

  18. Inconsistent Investment and Consumption Problems

    SciTech Connect

    Kronborg, Morten Tolver; Steffensen, Mogens

    2015-06-15

    In a traditional Black–Scholes market we develop a verification theorem for a general class of investment and consumption problems where the standard dynamic programming principle does not hold. The theorem is an extension of the standard Hamilton–Jacobi–Bellman equation in the form of a system of non-linear differential equations. We derive the optimal investment and consumption strategy for a mean-variance investor without pre-commitment endowed with labor income. In the case of constant risk aversion it turns out that the optimal amount of money to invest in stocks is independent of wealth. The optimal consumption strategy is given as a deterministic bang-bang strategy. In order to have a more realistic model we allow the risk aversion to be time and state dependent. Of special interest is the case were the risk aversion is inversely proportional to present wealth plus the financial value of future labor income net of consumption. Using the verification theorem we give a detailed analysis of this problem. It turns out that the optimal amount of money to invest in stocks is given by a linear function of wealth plus the financial value of future labor income net of consumption. The optimal consumption strategy is again given as a deterministic bang-bang strategy. We also calculate, for a general time and state dependent risk aversion function, the optimal investment and consumption strategy for a mean-standard deviation investor without pre-commitment. In that case, it turns out that it is optimal to take no risk at all.

  19. Building America Top Innovations 2013 Profile … Window Replacement, Rehabilitation, & Repair Guide

    Energy Saver

    Window Replacement, Rehabilitation, & Repair Guide TOP INNOVATOR: BSC Old single-glazed windows have such low thermal resistance that their effect on the overall thermal resistance of the walls can be staggering. Building America recommends several ways to improve the performance of existing windows at varying price points. Owners of older homes who want to improve their homes' efficiency often conclude that window replacement is a necessary first step. They are right that windows can be a

  20. DNA Repair Gene Expression and Risk of Locoregional Relapse in Breast Cancer Patients

    SciTech Connect

    Le Scodan, Romuald; Cizeron-Clairac, Geraldine

    2010-10-01

    Purpose: Radiation therapy appears to kill cells mainly by inducing DNA double-strand breaks. We investigated whether the DNA repair gene expression status might influence the risk of locoregional recurrence (LRR) in breast cancer patients. Methods and Materials: We used a quantitative reverse transcriptase PCR-based approach to measure messenger RNA levels of 20 selected DNA repair genes in tumor samples from 97 breast cancer patients enrolled in a phase III trial (Centre Rene Huguenin cohort). Normalized mRNA levels were tested for an association with LRR-free survival (LRR-FS) and overall survival (OS). The findings were validated in comparison with those of an independent cohort (Netherlands Cancer Institute (NKI) cohort). Multivariate analysis encompassing known prognostic factors was used to assess the association between DNA repair gene expression and patient outcome. Results: RAD51 was the only gene associated with LRR in both cohorts. With a median follow-up of 126 months in the CRH cohort, the 5-year LRR-FS and OS rates were 100% and 95% in the 61 patients with low RAD51 expression, compared with 70% and 69% in the 36 patients with high RAD51 expression, respectively (p < 0.001). RAD51 overexpression was associated with a higher risk of LRR (hazard ratio [HR], 12.83; 95% confidence interval [CI], 3.6-45.6) and death (HR, 4.10; 95% CI, 1.7-9.7). RAD51 overexpression was also significantly associated with shorter LRR-FS and OS in the NKI cohort. Conclusions: Overexpression of RAD51, a key component of the homologous DNA repair pathway, is associated with poor breast cancer outcome. This finding warrants prospective studies of RAD51 as a prognosticator and therapeutic target.

  1. Quality Improvement Guidelines for Imaging Detection and Treatment of Endoleaks following Endovascular Aneurysm Repair (EVAR)

    SciTech Connect

    Rand, T.; Uberoi, R.; Cil, B.; Munneke, G.; Tsetis, D.

    2013-02-15

    Major concerns after aortic aneurysm repair are caused by the presence of endoleaks, which are defined as persistent perigraft flow within the aortic aneurysm sac. Diagnosis of endoleaks can be performed with various imaging modalities, and indications for treatment are based on further subclassifications. Early detection and correct classification of endoleaks are crucial for planning patient management. The vast majority of endoleaks can be treated successfully by interventional means. Guidelines for Imaging Detection and Treatment of endoleaks are described in this article.

  2. To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair Dec. 1-20, 2006

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    From: ecchimento@comcast.net [mailto:ecchimento@comcast.net] Sent: Monday, January 29, 2007 6:28 PM To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Larry, Regarding the planned line outage, scheduled for Feb. 20 through Mar. 6, I am requesting that the residents near the plant be moved for the duration of the outage to protect their health. Would you include this comment also in the ongoing recorded discussion? Thank you. Elizabeth -----Original Message-----

  3. Analysis and testing of the DIII-D ohmic heating coil lead repair clamp

    SciTech Connect

    Reis, E.E.; Anderson, P.M.; Chin, E.; Robinson, J.I.

    1997-11-01

    DIII-D has been operating for the last year with limited volt-second capabilities due to structural failure of a conductor lead to one of the ohmic heating (OH) solenoids. The conductor failure was due to poor epoxy impregnation of the overwrap of the lead pack, resulting in copper fatigue and a water leak. A number of structural analyses were performed to assist in determining the failure scenario and to evaluate various repair options. A fatigue stress analysis of the leads with a failed epoxy overwrap indicated crack initiation after 1,000 cycles at the maximum operating conditions. The failure occurred in a very inaccessible area which restricted design repair options to concepts which could be implemented remotely. Several design options were considered for repairing the lead so that it can sustain the loads for 7.5 Vs conditions at full toroidal field. A clamp, along with preloaded banding straps and shim bags, provides a system that guarantees that the stress at the crack location is always compressive and prevents further crack growth in the conductor. Due to the limited space available for the repair, it was necessary to design the clamp system to operate at the material yield stress. The primary components of the clamp system were verified by load tests prior to installation. The main body of the clamp contains a load cell and potentiometer for monitoring the load-deflection characteristics of the clamp and conductors during plasma operation. Strain gages provides redundant instrumentation. If required, the preload on the conductors can be increased remotely by a special wrench attached to the clamp assembly.

  4. Laser-activated nano-biomaterials for tissue repair and controlled drug release

    SciTech Connect

    Matteini, P; Ratto, F; Rossi, F; Pini, R

    2014-07-31

    We present recent achievements of minimally invasive welding of biological tissue and controlled drug release based on laser-activated nano-biomaterials. In particular, we consider new advancements in the biomedical application of near-IR absorbing gold nano-chromophores as an original solution for the photothermal repair of surgical incisions and as nanotriggers of controlled drug release from hybrid biopolymer scaffolds. (laser biophotonics)

  5. Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency

    DOE PAGES [OSTI]

    Barnhoorn, Sander; Uittenboogaard, Lieneke M.; Jaarsma, Dick; Vermeij, Wilbert P.; Tresini, Maria; Weymaere, Michael; Menoni, Hervé; Brandt, Renata M. C.; de Waard, Monique C.; Botter, Sander M.; et al

    2014-10-09

    As part of the Nucleotide Excision Repair (NER) process, the endonuclease XPG is involved in repair of helix-distorting DNA lesions, but the protein has also been implicated in several other DNA repair systems, complicating genotype-phenotype relationship in XPG patients. Defects in XPG can cause either the cancer-prone condition xeroderma pigmentosum (XP) alone, or XP combined with the severe neurodevelopmental disorder Cockayne Syndrome (CS), or the infantile lethal cerebro-oculo-facio-skeletal (COFS) syndrome, characterized by dramatic growth failure, progressive neurodevelopmental abnormalities and greatly reduced life expectancy. Here, we present a novel (conditional) Xpg-/- mouse model which—in a C57BL6/FVB F1 hybrid genetic background—displays manymore » progeroid features, including cessation of growth, loss of subcutaneous fat, kyphosis, osteoporosis, retinal photoreceptor loss, liver aging, extensive neurodegeneration, and a short lifespan of 4–5 months. We show that deletion of XPG specifically in the liver reproduces the progeroid features in the liver, yet abolishes the effect on growth or lifespan. In addition, specific XPG deletion in neurons and glia of the forebrain creates a progressive neurodegenerative phenotype that shows many characteristics of human XPG deficiency. Our findings therefore exclude that both the liver as well as the neurological phenotype are a secondary consequence of derailment in other cell types, organs or tissues (e.g. vascular abnormalities) and support a cell-autonomous origin caused by the DNA repair defect itself. In addition they allow the dissection of the complex aging process in tissue- and cell-type-specific components. Moreover, our data highlight the critical importance of genetic background in mouse aging studies, establish the Xpg-/- mouse as a valid model for the severe form of human XPG patients and segmental accelerated aging, and strengthen the link between DNA damage and aging.« less

  6. Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency

    SciTech Connect

    Barnhoorn, Sander; Uittenboogaard, Lieneke M.; Jaarsma, Dick; Vermeij, Wilbert P.; Tresini, Maria; Weymaere, Michael; Menoni, Hervé; Brandt, Renata M. C.; de Waard, Monique C.; Botter, Sander M.; Sarker, Altaf H.; Jaspers, Nicolaas G. J.; van der Horst, Gijsbertus T. J.; Cooper, Priscilla K.; Hoeijmakers, Jan H. J.; van der Pluijm, Ingrid; Niedernhofer, Laura J.

    2014-10-09

    As part of the Nucleotide Excision Repair (NER) process, the endonuclease XPG is involved in repair of helix-distorting DNA lesions, but the protein has also been implicated in several other DNA repair systems, complicating genotype-phenotype relationship in XPG patients. Defects in XPG can cause either the cancer-prone condition xeroderma pigmentosum (XP) alone, or XP combined with the severe neurodevelopmental disorder Cockayne Syndrome (CS), or the infantile lethal cerebro-oculo-facio-skeletal (COFS) syndrome, characterized by dramatic growth failure, progressive neurodevelopmental abnormalities and greatly reduced life expectancy. Here, we present a novel (conditional) Xpg-/- mouse model which—in a C57BL6/FVB F1 hybrid genetic background—displays many progeroid features, including cessation of growth, loss of subcutaneous fat, kyphosis, osteoporosis, retinal photoreceptor loss, liver aging, extensive neurodegeneration, and a short lifespan of 4–5 months. We show that deletion of XPG specifically in the liver reproduces the progeroid features in the liver, yet abolishes the effect on growth or lifespan. In addition, specific XPG deletion in neurons and glia of the forebrain creates a progressive neurodegenerative phenotype that shows many characteristics of human XPG deficiency. Our findings therefore exclude that both the liver as well as the neurological phenotype are a secondary consequence of derailment in other cell types, organs or tissues (e.g. vascular abnormalities) and support a cell-autonomous origin caused by the DNA repair defect itself. In addition they allow the dissection of the complex aging process in tissue- and cell-type-specific components. Moreover, our data highlight the critical importance of genetic background in mouse aging studies, establish the Xpg-/- mouse as a valid model for the severe form of human XPG patients and segmental accelerated aging, and strengthen the link between DNA damage and aging.

  7. Inhibition of Hsp27 Radiosensitizes Head-and-Neck Cancer by Modulating Deoxyribonucleic Acid Repair

    SciTech Connect

    Guttmann, David M.; Hart, Lori; Du, Kevin; Seletsky, Andrew; Koumenis, Constantinos

    2013-09-01

    Purpose: To present a novel method of tumor radiosensitization through Hsp27 knockdown using locked nucleic acid (LNA) and to investigate the role of Hsp27 in DNA double strand break (DSB) repair. Methods and Materials: Clonogenic survival assays, immunoblotting, the proximity ligation assay, and ?H2AX foci analysis were conducted in SQ20B and FaDu human head-and-neck cancer cell lines treated with Hsp27 LNA and Hsp27 short hairpin RNA (shRNA). Additionally, nude mice with FaDu flank tumors were treated with fractionated radiation therapy after pretreatment with Hsp27 LNA and monitored for tumor growth. Results: Hsp27 LNA and Hsp27 shRNA radiosensitized head-and-neck cancer cell lines in an Hsp27-dependent manner. Ataxia-Telangectasia Mutated-mediated DNA repair signaling was impaired in irradiated cells with Hsp27 knockdown. ATM kinase inhibition abrogated the radiosensitizing effect of Hsp27. Furthermore, Hsp27 LNA and shRNA both attenuated DNA repair kinetics after radiation, and Hsp27 was found to colocalize with ATM in both untreated and irradiated cells. Last, combined radiation and Hsp27 LNA treatment in tumor xenografts in nude mice suppressed tumor growth compared with either treatment alone. Conclusions: These results support a radiosensitizing property of Hsp27 LNA in vitro and in vivo, implicate Hsp27 in double strand break repair, and suggest that Hsp27 LNA might eventually serve as an effective clinical agent in the radiotherapy of head-and-neck cancer.

  8. Endovascular Repair of an Actively Hemorrhaging Stab Wound Injury to the Abdominal Aorta

    SciTech Connect

    Hussain, Qasim; Maleux, Geert Heye, Sam; Fourneau, Inge

    2008-09-15

    Traumatic injury of the abdominal aorta is rare and potentially lethal (Yeh et al., J Vasc Surg 42(5):1007-1009, 2005; Chicos et al., Chirurgia (Bucur) 102(2):237-240, 2007) as it can result in major retroperitoneal hemorrhage, requiring an urgent open surgery. In case of concomitant bowel injury or other conditions of hostile abdomen, endovascular repair can be an alternative treatment. This case report deals with a 50-year-old man presenting at the emergency ward with three stab wounds: two in the abdomen and one in the chest. During explorative laparotomy, liver laceration and bowel perforation were repaired. One day later, abdominal CT-scan revealed an additional retroperitoneal hematoma associated with an aortic pseudoaneurysm, located anteriorly 3 cm above the aortic bifurcation. Because of the risk of graft infection, an endovascular repair of the aortic injury using a Gore excluder stent-graft was performed. Radiological and clinical follow-up revealed a gradual shrinkage of the pseudo-aneurysm and no sign of graft infection at two years' follow-up.

  9. ASTRID sodium cooled fast reactor: Program for improving in service inspection and repair

    SciTech Connect

    Jadot, F.; De Dinechin, G.; Augem, J. M.; Sibilo, J.

    2011-07-01

    In the frame of the CEA, EDF, AREVA coordinated research program for the development of Generation IV sodium-cooled fast reactors (SFR), the ASTRID project was launched in 2010. For the future prototype, the improvement of in-service inspection and repair (ISI and R) capabilities was identified as a major issue. Following the pluri-annual SFR research program, the ISI and R main R and D axes remain: i) improvement of the primary system conceptual design, ii) development of measurement and inspection techniques (continuous monitoring instrumentation and periodic inspection tools), iii) accessibility and associated robotics, and iv) development and validation of repair processes. Associated ISI and R needs are being defined through an iterative method between designers and instrumentation specialists: adaptation of the Design to ISI and R requirements, fission chamber development, validation of the ultrasonic and chemical transducers, of ultrasonic non destructive simulation, of acoustic surveillance, of laser repair intervention processes, of connected robotic equipment. Moreover, CEA, as leader of the ASTRID Project, is willing to find new contributors, partners or suppliers, in order to get innovative, diversified, exhaustive and efficient solutions. (authors)

  10. Reduced Activity of Double-Strand Break Repair Genes in Prostate Cancer Patients With Late Normal Tissue Radiation Toxicity

    SciTech Connect

    Oorschot, Bregje van; Hovingh, Suzanne E.; Moerland, Perry D.; Medema, Jan Paul; Stalpers, Lukas J.A.; Vrieling, Harry; Franken, Nicolaas A.P.

    2014-03-01

    Purpose: To investigate clinical parameters and DNA damage response as possible risk factors for radiation toxicity in the setting of prostate cancer. Methods and Materials: Clinical parameters of 61 prostate cancer patients, 34 with (overresponding, OR) and 27 without (non-responding, NR) severe late radiation toxicity were assembled. In addition, for a matched subset the DNA damage repair kinetics (γ-H2AX assay) and expression profiles of DNA repair genes were determined in ex vivo irradiated lymphocytes. Results: Examination of clinical data indicated none of the considered clinical parameters to be correlated with the susceptibility of patients to develop late radiation toxicity. Although frequencies of γ-H2AX foci induced immediately after irradiation were similar (P=.32), significantly higher numbers of γ-H2AX foci were found 24 hours after irradiation in OR compared with NR patients (P=.03). Patient-specific γ-H2AX foci decay ratios were significantly higher in NR patients than in OR patients (P<.0001). Consequently, NR patients seem to repair DNA double-strand breaks (DSBs) more efficiently than OR patients. Moreover, gene expression analysis indicated several genes of the homologous recombination pathway to be stronger induced in NR compared with OR patients (P<.05). A similar trend was observed in genes of the nonhomologous end-joining repair pathway (P=.09). This is congruent with more proficient repair of DNA DSBs in patients without late radiation toxicity. Conclusions: Both gene expression profiling and DNA DSB repair kinetics data imply that less-efficient repair of radiation-induced DSBs may contribute to the development of late normal tissue damage. Induction levels of DSB repair genes (eg, RAD51) may potentially be used to assess the risk for late radiation toxicity.

  11. ACOUSTICAL IMAGING AND MECHANICAL PROPERTIES OF SOFT ROCK AND MARINE SEDIMENTS

    SciTech Connect

    Thurman E. Scott, Jr., Ph.D.; Musharraf Zaman, Ph.D.; Younane Abousleiman, Ph.D.

    2001-04-01

    The oil and gas industry has encountered significant problems in the production of oil and gas from weak rocks (such as chalks and limestones) and from unconsolidated sand formations. Problems include subsidence, compaction, sand production, and catastrophic shallow water sand flows during deep water drilling. Together these cost the petroleum industry hundreds of millions of dollars annually. The goals of this first quarterly report is to document the progress on the project to provide data on the acoustic imaging and mechanical properties of soft rock and marine sediments. The project is intended to determine the geophysical (acoustic velocities) rock properties of weak, poorly cemented rocks and unconsolidated sands. In some cases these weak formations can create problems for reservoir engineers. For example, it cost Phillips Petroleum 1 billion dollars to repair of offshore production facilities damaged during the unexpected subsidence and compaction of the Ekofisk Field in the North Sea (Sulak 1991). Another example is the problem of shallow water flows (SWF) occurring in sands just below the seafloor encountered during deep water drilling operations. In these cases the unconsolidated sands uncontrollably flow up around the annulus of the borehole resulting in loss of the drill casing. The $150 million dollar loss of the Ursa development project in the U.S. Gulf Coast resulted from an uncontrolled SWF (Furlow 1998a,b; 1999a,b). The first three tasks outlined in the work plan are: (1) obtain rock samples, (2) construct new acoustic platens, (3) calibrate and test the equipment. These have been completed as scheduled. Rock Mechanics Institute researchers at the University of Oklahoma have obtained eight different types of samples for the experimental program. These include: (a) Danian Chalk, (b) Cordoba Cream Limestone, (c) Indiana Limestone, (d) Ekofisk Chalk, (e) Oil Creek Sandstone, (f) unconsolidated Oil Creek sand, and (g) unconsolidated Brazos river sand

  12. Relationship of DNA repair processes to mutagenesis and carcinogenesis in mammalian cells. Progress report, August 1, 1977-October 31, 1980

    SciTech Connect

    Evans, H.H.

    1980-10-01

    The objective of this research is to determine the role of DNA repair in mutagenesis and carcinogenesis in mammalian cells. More specifically, mutant strains will be selected which are deficient in various DNA repair pathways. These strains will be studied with regard to (1) the nature of the defect in repair, and (2) the mutability and transformability of the defective cells by various agents as compared to the wild type parental cells. The results to date include progress in the following areas: (1) determination of optimum conditions for growth and maintenance of cells and for quantitative measurement of various cellular parameters; (2) investigation of the effect of holding mutagenized cells for various periods in a density inhibited state on survival and on mutation and transformation frequencies; (3) examination of the repair capabilities of BHK cells, as compared to repair-proficient and repair-deficient human cells and excision-deficient mouse cells, as measured by the reactivation of Herpes simplex virus (HSV) treated with radiation and ethylmethane sulfonate (EMS); (4) initiation of host cell reactivation viral sucide enrichment and screening of survivors of the enrichment for sensitivity to ionizing radiation; and (5) investigation of the toxicity, mutagenicity, and carcinogenicity of various metabolites of 4-nitroquinoline-1-oxide (4-NQO). (ERB)

  13. Enhancements of branch and bound methods for the maximal constraint satisfaction problem

    SciTech Connect

    Wallace, R.J.

    1996-12-31

    Two methods are described for enhancing performance of branch and bound methods for overconstrained CSPs. These methods improve either the upper or lower bound, respectively, during search, so the two can be combined. Upper bounds are improved by using heuristic repair methods before search to find a good solution quickly, whose cost is used as the initial upper bound. The method for improving lower bounds is an extension of directed arc consistency preprocessing, used in conjunction with forward checking. After computing directed arc consistency counts, inferred counts are computed for all values based on minimum counts for values of adjacent variables that are later in the search order. This inference process can be iterated, so that counts are cascaded from the end to the beginning of the search order, to augment the initial counts. Improvements in time and effort are demonstrated for both techniques using random problems.

  14. HYDRAULIC SERVO CONTROL MECHANISM

    DOEpatents

    Hussey, R.B.; Gottsche, M.J. Jr.

    1963-09-17

    A hydraulic servo control mechanism of compact construction and low fluid requirements is described. The mechanism consists of a main hydraulic piston, comprising the drive output, which is connected mechanically for feedback purposes to a servo control piston. A control sleeve having control slots for the system encloses the servo piston, which acts to cover or uncover the slots as a means of controlling the operation of the system. This operation permits only a small amount of fluid to regulate the operation of the mechanism, which, as a result, is compact and relatively light. This mechanism is particuiarly adaptable to the drive and control of control rods in nuclear reactors. (auth)

  15. Mechanical seal assembly

    DOEpatents

    Kotlyar, Oleg M.

    2001-01-01

    An improved mechanical seal assembly is provided for sealing rotating shafts with respect to their shaft housings, wherein the rotating shafts are subject to substantial axial vibrations. The mechanical seal assembly generally includes a rotating sealing ring fixed to the shaft, a non-rotating sealing ring adjacent to and in close contact with the rotating sealing ring for forming an annular seal about the shaft, and a mechanical diode element that applies a biasing force to the non-rotating sealing ring by means of hemispherical joint. The alignment of the mechanical diode with respect to the sealing rings is maintained by a series of linear bearings positioned axially along a desired length of the mechanical diode. Alternative embodiments include mechanical or hydraulic amplification components for amplifying axial displacement of the non-rotating sealing ring and transferring it to the mechanical diode.

  16. Mechanical seal assembly

    DOEpatents

    Kotlyar, Oleg M.

    2002-01-01

    An improved mechanical seal assembly is provided for sealing rotating shafts with respect to their shaft housings, wherein the rotating shafts are subject to substantial axial vibrations. The mechanical seal assembly generally includes a rotating sealing ring fixed to the shaft, a non-rotating sealing ring adjacent to and in close contact with the rotating sealing ring for forming an annular seal about the shaft, and a mechanical diode element that applies a biasing force to the non-rotating sealing ring by means of hemispherical joint. The alignment of the mechanical diode with respect to the sealing rings is maintained by a series of linear bearings positioned axially along a desired length of the mechanical diode. Alternative embodiments include mechanical or hydraulic amplification components for amplifying axial displacement of the non-rotating sealing ring and transfering it to the mechanical diode.

  17. Development and validation of nondestructive inspection techniques for composite doubler repairs on commercial aircraft

    SciTech Connect

    Roach, D.; Walkington, P.

    1998-05-01

    Composite doublers, or repair patches, provide an innovative repair technique which can enhance the way aircraft are maintained. Instead of riveting multiple steel or aluminum plates to facilitate an aircraft repair, it is possible to bond a single boron-epoxy composite doubler to the damaged structure. In order for the use of composite doublers to achieve widespread use in the civil aviation industry, it is imperative that methods be developed which can quickly and reliably assess the integrity of the doubler. In this study, a specific composite application was chosen on an L-1011 aircraft in order to focus the tasks on application and operation issues. Primary among inspection requirements for these doublers is the identification of disbonds, between the composite laminate and aluminum parent material, and delaminations in the composite laminate. Surveillance of cracks or corrosion in the parent aluminum material beneath the doubler is also a concern. No single nondestructive inspection (NDI) method can inspect for every flaw type, therefore it is important to be aware of available NDI techniques and to properly address their capabilities and limitations. A series of NDI tests were conducted on laboratory test structures and on full-scale aircraft fuselage sections. Specific challenges, unique to bonded composite doubler applications, were highlighted. An array of conventional and advanced NDI techniques were evaluated. Flaw detection sensitivity studies were conducted on applicable eddy current, ultrasonic, X-ray and thermography based devices. The application of these NDI techniques to composite doublers and the results from test specimens, which were loaded to provide a changing flaw profile, are presented in this report. It was found that a team of these techniques can identify flaws in composite doubler installations well before they reach critical size.

  18. Fusion, mechanical joining methods pros, cons--Part 2. [Natural gas pipelines use of mechanical and fusion joints

    SciTech Connect

    Gunther, K.M. )

    1993-10-01

    Two basic techniques accepted by gas distribution utility companies for joining polyethylene pipe underground are fusion methods and mechanical joining. Washington Gas Light Co., uses the fusion methods for the most part and uses mechanical joints for repair and final tie-ins where fusion methods are impractical or impossible to use. Fusion methods used by gas industry users of plastic pipe are: butt fusion; socket fusion; saddle fusion; electrofusion. Mechanical pipe joining techniques or procedures include: factory made mechanical joints such as meter risers and transition fittings; hydraulic compression couplings; bolted and screwed compression couplings; stab type compression couplings; interior seal couplings. Every joining method has strengths, weaknesses, pitfalls and ways they can fail in service. The key is making the best selection based on such factors as location, temperature, conditions, available equipment, personnel training level and cost. No one method will do it all or every company would be using that particular method. Part 2 focuses on strengths, weaknesses, pitfalls and failure possibilities of the five mechanical techniques.

  19. Failures and repairs of headers and drums in fossil fired boilers

    SciTech Connect

    Thielsch, H.; Cone, F.

    1995-12-01

    This paper discusses failures which have occurred in a number of thick-walled pressure vessels including superheater and reheat outlet headers, and med and steam drums in fossil fired boilers. It provides details regarding the causes of failure, which range from original manufacturing defects to service-related deterioration such as creep and thermal fatigue. It also provides information regarding inspection techniques which are capable of detecting similar conditions before they have reached dangerous levels of deterioration. Finally, it provides details pertaining to techniques used to successfully repair these pressure vessels when they have failed.

  20. JAG Tearing Technique with Radiofrequency Guide Wire for Aortic Fenestration in Thoracic Endovascular Aneurysm Repair

    SciTech Connect

    Ricci, Carmelo; Ceccherini, Claudio Leonini, Sara; Cini, Marco; Vigni, Francesco; Neri, Eugenio; Tucci, Enrico; Benvenuti, Antonio; Tommasino, Giulio; Sassi, Carlo

    2012-02-15

    An innovative approach, the JAG tearing technique, was performed during thoracic endovascular aneurysm repair in a patient with previous surgical replacement of the ascending aorta with a residual uncomplicated type B aortic dissection who developed an aneurysm of the descending thoracic aorta with its lumen divided in two parts by an intimal flap. The proximal landing zone was suitable to place a thoracic stent graft. The distal landing zone was created by cutting the intimal flap in the distal third of the descending thoracic aorta with a radiofrequency guide wire and intravascular ultrasound catheter.

  1. Structure of DNA-Bound FEN1 Reveals Mechanism of Action

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    50 million times without introducing any errors. But FEN1 is also important in DNA repair, targeting specific repair pathways, which presents different challenges than...

  2. Mechanical Systems Qualification Standard

    Office of Environmental Management (EM)

    June 2008 DOE STANDARD MECHANICAL SYSTEMS QUALIFICATION STANDARD DOE Defense Nuclear Facilities Technical Personnel U.S. Department of Energy AREA TRNG Washington, D.C. 20585 ...

  3. Monroe Thomas, Mechanical Technician

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    and endstation moves. Though he's training another mechanical technician to operate the crane, it's Monroe who is called upon for critical moves. He plays a key role in...

  4. Determination of Mechanical Properties

    Office of Scientific and Technical Information (OSTI)

    ... Monofilament Laminates," paper 61-AV56 presented at American Society of Mechanical Engineers Aviation Conference, Los Angeles, California (March 1961). 21. G. S. Springer and s. ...

  5. Heavy Mobile Equipment Mechanic

    Energy.gov [DOE]

    Join the Bonneville Power Administration (BPA) for a challenging and rewarding career, while working, living, and playing in the Pacific Northwest. The Heavy Mobile Equipment Mechanic (HMEM)...

  6. Student's algorithm solves real-world problem

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Student's algorithm solves real-world problem Supercomputing Challenge: student's algorithm solves real-world problem Students learn how to use powerful computers to analyze, model, and solve real-world problems. April 3, 2012 Jordon Medlock of Albuquerque's Manzano High School won the 2012 Lab-sponsored Supercomputing Challenge Jordon Medlock of Albuquerque's Manzano High School won the 2012 Lab-sponsored Supercomputing Challenge by creating a computer algorithm that automates the process of

  7. Plugging mechanisms in a lost circulation model

    SciTech Connect

    Givler, R.C.

    1985-01-01

    The problem of lost circulation during the drilling of geothermal wells is recognized to be a serious impediment to well completion. A viable solution, in terms of an ''engineered'' plugging material, will be enhanced via analytical cognizance of possible down-hole plugging mechanisms. This paper investigates several plugging strategies that result from rudimentary, mathematical models of the mud rheology (with and without dispersed particulate). 10 refs., 7 figs.

  8. design problem | OpenEI Community

    OpenEI (Open Energy Information) [EERE & EIA]

    design problem Home Dc's picture Submitted by Dc(266) Contributor 15 November, 2013 - 13:26 Living Walls ancient building system architect biomimicry building technology cooling cu...

  9. PCx: Optimization Problem Solver | Argonne National Laboratory

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    programming problems. Windows 95 version includes a user-friendly graphical interface Java graphical interface is available for all environments Source code is available and...

  10. Approximate resolution of hard numbering problems

    SciTech Connect

    Bailleux, O.; Chabrier, J.J.

    1996-12-31

    We present a new method for estimating the number of solutions of constraint satisfaction problems. We use a stochastic forward checking algorithm for drawing a sample of paths from a search tree. With this sample, we compute two values related to the number of solutions of a CSP instance. First, an unbiased estimate, second, a lower bound with an arbitrary low error probability. We will describe applications to the Boolean Satisfiability problem and the Queens problem. We shall give some experimental results for these problems.

  11. Engineering report standard hydrogen monitoring system problems

    SciTech Connect

    Golberg, R.L.

    1996-09-25

    Engineering Report to document moisture problems found during the sampling of the vapors in the dome space for hydrogen in the storage tanks and a recommended solution.

  12. Tackling Energy Problems For America's Tribal Nations

    Energy.gov [DOE]

    The Energy Department is bringing in more tribes to confront the most pressing energy problems for Tribal Nations across the country.

  13. The {open_quotes}first{close_quotes} problem

    SciTech Connect

    Holsinger, R.F.

    1995-02-01

    This paper describes the first magnet design problem that Klaus and the author worked on together. At the time, over 30 years ago, Klaus was working as a plasma physicist in the Controlled Thermonuclear Research (CTR) Group, and the author was assigned from the Mechanical Engineering Department to help with the design of experimental equipment for various research projects. Klaus` primary research program was to develop a {open_quotes}plasma gun{close_quotes} for injecting plasma into {open_quotes}mirror machines.{close_quotes} As described, the magnet design aspect of this plasma gun was a challenging task, and led to some innovations that were quite advanced at that time.

  14. A Branch and Bound Approach for Truss Topology Design Problems with Valid Inequalities

    SciTech Connect

    Cerveira, Adelaide; Agra, Agostinho; Bastos, Fernando; Varum, Humberto

    2010-09-30

    One of the classical problems in the structural optimization field is the Truss Topology Design Problem (TTDP) which deals with the selection of optimal configuration for structural systems for applications in mechanical, civil, aerospace engineering, among others. In this paper we consider a TTDP where the goal is to find the stiffest truss, under a given load and with a bound on the total volume. The design variables are the cross-section areas of the truss bars that must be chosen from a given finite set. This results in a large-scale non-convex problem with discrete variables. This problem can be formulated as a Semidefinite Programming Problem (SDP problem) with binary variables. We propose a branch and bound algorithm to solve this problem. In this paper it is considered a binary formulation of the problem, to take advantage of its structure, which admits a Knapsack problem as subproblem. Thus, trying to improve the performance of the Branch and Bound, at each step, some valid inequalities for the Knapsack problem are included.

  15. Mechanical code comparator

    DOEpatents

    Peter, Frank J.; Dalton, Larry J.; Plummer, David W.

    2002-01-01

    A new class of mechanical code comparators is described which have broad potential for application in safety, surety, and security applications. These devices can be implemented as micro-scale electromechanical systems that isolate a secure or otherwise controlled device until an access code is entered. This access code is converted into a series of mechanical inputs to the mechanical code comparator, which compares the access code to a pre-input combination, entered previously into the mechanical code comparator by an operator at the system security control point. These devices provide extremely high levels of robust security. Being totally mechanical in operation, an access control system properly based on such devices cannot be circumvented by software attack alone.

  16. Tsirelson's problem and asymptotically commuting unitary matrices...

    Office of Scientific and Technical Information (OSTI)

    Language: English Subject: 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; 97 MATHEMATICAL METHODS AND COMPUTING; ALGEBRA; CORRELATIONS; INTERACTIONS; MATRICES; UNITARY ...

  17. Effect of thermo-mechanical treatment on mechanical and elastic...

    Office of Scientific and Technical Information (OSTI)

    Effect of thermo-mechanical treatment on mechanical and elastic properties of Ti-36Nb-5Zr alloy Title: Effect of thermo-mechanical treatment on mechanical and elastic properties of ...

  18. Specification of the Advanced Burner Test Reactor Multi-Physics Coupling Demonstration Problem

    SciTech Connect

    Shemon, E. R.; Grudzinski, J. J.; Lee, C. H.; Thomas, J. W.; Yu, Y. Q.

    2015-12-21

    This document specifies the multi-physics nuclear reactor demonstration problem using the SHARP software package developed by NEAMS. The SHARP toolset simulates the key coupled physics phenomena inside a nuclear reactor. The PROTEUS neutronics code models the neutron transport within the system, the Nek5000 computational fluid dynamics code models the fluid flow and heat transfer, and the DIABLO structural mechanics code models structural and mechanical deformation. The three codes are coupled to the MOAB mesh framework which allows feedback from neutronics, fluid mechanics, and mechanical deformation in a compatible format.

  19. Operational results of shaft repair by installing stave type cooler at Kimitsu Nos. 3 and 4 blast furnaces

    SciTech Connect

    Oda, Hiroshi; Amano, Shigeru; Sakamoto, Aiichiro; Anzai, Osamu; Nakagome, Michiru; Kuze, Toshisuke; Imuta, Akira

    1997-12-31

    Nos. 3 and 4 blast furnaces in Nippon Steel Corporation Kimitsu Works were both initially fitted with cooling plate systems. With the aging of each furnace, the damage to their respective inner-shaft profiles had become serious. Thus, in order to prevent operational change and prolong the furnace life, the inner-shaft profile of each furnace was repaired by replacing the former cooling plate system with the stave type cooler during the two-week-shutdowns. With this repair, stability of burden descent and gas flow near the wall part of the furnace have been achieved. Thus the prolongation of the furnace life is naturally expected.

  20. Planning and care mark repair of 14-year old leak in Kuwait Oil Co. LPG tank 95

    SciTech Connect

    Shtayieh, S.

    1983-01-10

    This paper points out that the leak, which had been present for such a long time, completely saturated the perlite insulation with hydrocarbons, thus rendering the entire operation of inspection, repair, and maintenance of the inner tank a hazardous operation. It emphasizes the safety aspects, which were complicated by the saturated perlite as well as by the fact that the tank is situated in the middle of the LPG storage area with LPG tanks on either side. Tank design, making preparations, inspection, and repair are discussed. The fact that the leaking flanges were originally installed damaged, indicated the future need of tighter company quality control of all contractors work.

  1. Experimental studies of a quantum-mechanical three-body problem

    Office of Scientific and Technical Information (OSTI)

    ... Harris, H. C. Bryant, A. H. Mohagheghi, R. A. Reeder, H. Sharifian, C. Y. Tang, H. Tootoonchi, J. B. Donahue, C. R. Quick, D. C. Rislove, W. W. Smith, and J. E. Stewart, Phys. Rev. ...

  2. Integrated network design and scheduling problems :

    SciTech Connect

    Nurre, Sarah G.; Carlson, Jeffrey J.

    2014-01-01

    We consider the class of integrated network design and scheduling problems. These problems focus on selecting and scheduling operations that will change the characteristics of a network, while being speci cally concerned with the performance of the network over time. Motivating applications of INDS problems include infrastructure restoration after extreme events and building humanitarian distribution supply chains. While similar models have been proposed, no one has performed an extensive review of INDS problems from their complexity, network and scheduling characteristics, information, and solution methods. We examine INDS problems under a parallel identical machine scheduling environment where the performance of the network is evaluated by solving classic network optimization problems. We classify that all considered INDS problems as NP-Hard and propose a novel heuristic dispatching rule algorithm that selects and schedules sets of arcs based on their interactions in the network. We present computational analysis based on realistic data sets representing the infrastructures of coastal New Hanover County, North Carolina, lower Manhattan, New York, and a realistic arti cial community CLARC County. These tests demonstrate the importance of a dispatching rule to arrive at near-optimal solutions during real-time decision making activities. We extend INDS problems to incorporate release dates which represent the earliest an operation can be performed and exible release dates through the introduction of specialized machine(s) that can perform work to move the release date earlier in time. An online optimization setting is explored where the release date of a component is not known.

  3. AMRH and High Energy Reinicke Problem

    SciTech Connect

    Shestakov, A I; Greenough, J A

    2001-05-14

    The authors describe AMRH results on a version of the Reinicke problem specified by the V and V group of LLNL's A-Div. The simulation models a point explosion with heat conduction. The problem specification requires that the heat conduction be replaced with diffusive radiation transport. The matter and radiation energy densities are tightly coupled.

  4. Electronic door locking mechanism

    DOEpatents

    Williams, Gary Lin; Kirby, Patrick Gerald

    1997-01-01

    The invention is a motorized linkage for engaging a thumb piece in a door mechanism. The device has an exterior lock assembly with a small battery cell and combination lock. Proper entry by a user of a security code allows the battery to operate a small motor within the exterior lock assembly. The small motor manipulates a cam-plunger which moves an actuator pin into a thumb piece. The user applies a force on to the thumb piece. This force is transmitted by the thumb piece to a latch engagement mechanism by the actuator pin. The latch engagement mechanism operates the door latch.

  5. Electronic door locking mechanism

    DOEpatents

    Williams, G.L.; Kirby, P.G.

    1997-10-21

    The invention is a motorized linkage for engaging a thumb piece in a door mechanism. The device has an exterior lock assembly with a small battery cell and combination lock. Proper entry by a user of a security code allows the battery to operate a small motor within the exterior lock assembly. The small motor manipulates a cam-plunger which moves an actuator pin into a thumb piece. The user applies a force on to the thumb piece. This force is transmitted by the thumb piece to a latch engagement mechanism by the actuator pin. The latch engagement mechanism operates the door latch. 6 figs.

  6. Rotary mechanical latch

    SciTech Connect

    Spletzer, Barry L.; Martinez, Michael A.; Marron, Lisa C.

    2012-11-13

    A rotary mechanical latch for positive latching and unlatching of a rotary device with a latchable rotating assembly having a latching gear that can be driven to latched and unlatched states by a drive mechanism such as an electric motor. A cam arm affixed to the latching gear interfaces with leading and trailing latch cams affixed to a flange within the drive mechanism. The interaction of the cam arm with leading and trailing latch cams prevents rotation of the rotating assembly by external forces such as those due to vibration or tampering.

  7. Failure mechanisms in MEMS.

    SciTech Connect

    Walraven, Jeremy Allen

    2003-07-01

    MEMS components by their very nature have different and unique failure mechanisms than their macroscopic counterparts. This paper discusses failure mechanisms observed in various MEMS components and technologies. MEMS devices fabricated using bulk and surface micromachining process technologies are emphasized. MEMS devices offer uniqueness in their application, fabrication, and functionality. Their uniqueness creates various failure mechanisms not typically found in their bulk or IC counterparts. In ICs, electrical precautions are taken to mitigate failure. In MEMS, both electrical and mechanical precautions must be enacted to reduce the risk of failure and increased reliability. Unlike ICs, many MEMS components are designed to interact with their environment, making the fabrication, testing, and packaging processes critical for the success of the device.

  8. ELECTROMAGNETIC RELEASE MECHANISM

    DOEpatents

    Michelson, C.

    1960-09-13

    An electromagnetic release mechanism is offered that may be used, for example, for supporting a safety rod for a nuclear reactor. The release mechanism is designed to have a large excess holding force and a rapid, uniform, and dependable release. The fast release is accomplished by providing the electromagnet with slotttd polts separated by an insulating potting resin, and by constructing the poles with a ferro-nickel alloy. The combination of these two features materially reduces the eddy current power density whenever the magnetic field changes during a release operation. In addition to these features, the design of the armature is such as to provide ready entrance of fluid into any void that might tend to form during release of the armature. This also improves the release time for the mechanism. The large holding force for the mechanism is accomplished by providing a small, selected, uniform air gap between the inner pole piece and the armature.

  9. Renewable Auction Mechanism (RAM)

    Energy.gov [DOE]

    The Renewable Auction Mechanism (RAM) was approved by the California Public Utilities Commission (CPUC) in December 2010 with a goal of installing 1,500 megawatts (MW) of new distributed generation...

  10. Phase Field Fracture Mechanics.

    SciTech Connect

    Robertson, Brett Anthony

    2015-11-01

    For this assignment, a newer technique of fracture mechanics using a phase field approach, will be examined and compared with experimental data for a bend test and a tension test. The software being used is Sierra Solid Mechanics, an implicit/explicit finite element code developed at Sandia National Labs in Albuquerque, New Mexico. The bend test experimental data was also obtained at Sandia Labs while the tension test data was found in a report online from Purdue University.

  11. REACTOR CONTROL MECHANISM

    DOEpatents

    Lane, J.A.; Engberg, R.E.; Welch, J.M.

    1959-05-12

    A quick-releasing mechanism is described which may be used to rapidiy drop a device supported from beneath during normal use, such as a safety rod in a nuclear reactor. In accordance with this invention an electrical control signal, such as may be provided by radiation detection or other alarm condition sensing devices, is delivered to an electromagnetic solenoid, the armature of which is coupled to an actuating mechanism. The solenoid is energized when the mechanism is in its upper or cocked position. In such position, the mechanism engages a plurality of retaining balls, forcing them outward into engagement with a shoulder or recess in a corresponding section of a tubular extension on the upheld device. When the control signal to the solenoid suddenly ceases, the armature drops out, allowing the actuating mechanism to move slightly but rapidly under the force of a compressed spring. The weight of the device will urge the balls inward against a beveled portion of the actuating mechanism and away from the engaging section on the tubular extension, thus allowing the upheld device to fall freely under the influence of gravity.

  12. SIENA Customer Problem Statement and Requirements

    SciTech Connect

    L. Sauer; R. Clay; C. Adams; H. Walther; B. Allan; R. Mariano; C. Poore; B. Whiteside; B. Boughton; J. Dike; E. Hoffman; R. Hogan; C. LeGall

    2000-08-01

    This document describes the problem domain and functional requirements of the SIENA framework. The software requirements and system architecture of SIENA are specified in separate documents (called SIENA Software Requirement Specification and SIENA Software Architecture, respectively). While currently this version of the document describes the problems and captures the requirements within the Analysis domain (concentrating on finite element models), it is our intention to subsequent y expand this document to describe problems and capture requirements from the Design and Manufacturing domains. In addition, SIENA is designed to be extendible to support and integrate elements from the other domains (see SIENA Software Architecture document).

  13. Mitigating PQ Problems in Legacy Data Centers

    SciTech Connect

    Ilinets, Boris; /SLAC

    2011-06-01

    The conclusions of this presentation are: (1) Problems with PQ in legacy data centers still exist and need to be mitigated; (2) Harmonics generated by non-linear IT load can be lowered by passive, active and hybrid cancellation methods; (3) Harmonic study is necessary to find the best way to treat PQ problems; (4) AHF's and harmonic cancellation transformers proved to be very efficient in mitigating PQ problems; and (5) It is important that IT leaders partner with electrical engineering to appropriate ROI statements, justifying many of these expenditures.

  14. Studies in nonlinear problems of energy

    SciTech Connect

    Matkowsky, B.J.

    1990-11-01

    We carry out a research program with primary emphasis on the applications of Bifurcation and Stability Theory to Problems of energy, with specific emphasis on Problems of Combustion and Flame Propagation. In particular we consider the problem of transition from laminar to turbulent flame propagation. A great deal of progress has been made in our investigations. More than one hundred and thirty papers citing this project have been prepared for publication in technical journals. A list of the papers, including abstracts for each paper, is appended to this report.

  15. Dimer monomer transition and dimer re-formation play important role for ATM cellular function during DNA repair

    SciTech Connect

    Du, Fengxia; Zhang, Minjie; Li, Xiaohua; Yang, Caiyun; Meng, Hao; Wang, Dong; Chang, Shuang; Xu, Ye; Price, Brendan; Sun, Yingli

    2014-10-03

    Highlights: • ATM phosphorylates the opposite strand of the dimer in response to DNA damage. • The PETPVFRLT box of ATM plays a key role in its dimer dissociation in DNA repair. • The dephosphorylation of ATM is critical for dimer re-formation after DNA repair. - Abstract: The ATM protein kinase, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks, mediates responses to ionizing radiation in mammalian cells. Here we show that ATM is held inactive in unirradiated cells as a dimer and phosphorylates the opposite strand of the dimer in response to DNA damage. Cellular irradiation induces rapid intermolecular autophosphorylation of serine 1981 that causes dimer dissociation and initiates cellular ATM kinase activity. ATM cannot phosphorylate the substrates when it could not undergo dimer monomer transition. After DNA repair, the active monomer will undergo dephosphorylation to form dimer again and dephosphorylation is critical for dimer re-formation. Our work reveals novel function of ATM dimer monomer transition and explains why ATM dimer monomer transition plays such important role for ATM cellular activity during DNA repair.

  16. Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions

    SciTech Connect

    Zafar, Faria; Seidler, Sara B.; Kronenberg, Amy; Schild, David; Wiese, Claudia

    2010-06-29

    To test the contribution of homologous recombinational repair (HRR) in repairing DNA damaged sites induced by high-energy iron ions, we used: (1) HRR-deficient rodent cells carrying a deletion in the RAD51D gene and (2) syngeneic human cells impaired for HRR by RAD51D or RAD51 knockdown using RNA interference. We show that in response to iron ions, HRR contributes to cell survival in rodent cells, and that HRR-deficiency abrogates RAD51 foci formation. Complementation of the HRR defect by human RAD51D rescues both enhanced cytotoxicity and RAD51 foci formation. For human cells irradiated with iron ions, cell survival is decreased, and, in p53 mutant cells, the levels of mutagenesis are increased when HRR is impaired. Human cells synchronized in S phase exhibit more pronounced resistance to iron ions as compared with cells in G1 phase, and this increase in radioresistance is diminished by RAD51 knockdown. These results implicate a role for RAD51-mediated DNA repair (i.e. HRR) in removing a fraction of clustered lesions induced by charged particle irradiation. Our results are the first to directly show the requirement for an intact HRR pathway in human cells in ensuring DNA repair and cell survival in response to high-energy high LET radiation.

  17. Designer's guidebook for first wall/blanket/shield assembly, maintenance, and repair

    SciTech Connect

    Not Available

    1983-12-30

    This is the initial issue of the guidebook. Since a guidebook of this type must incorporate information concerning a wide range of subjects, much additional data will eventually be included. The guidebook will document, in summary and easily referenceable form, data, designs, design concepts, design guidelines and background information useful to the FWBS and to the Maintenance System designer. In providing guidelines for the AMR of the FWBS, the guidebook must, of necessity, include guidelines for all aspects of maintenance associated with the FWBS. These include most maintenance operations within the reactor room necessary to gain access, identify faults, and handle equipment related to FWBS maintenance. In addition, the guidelines include those required to define facility requirements for handling and repair of FWBS and related reactor components external to the reactor room. Particular emphasis is given to remote maintenance design and operations.

  18. Method and apparatus for in-system redundant array repair on integrated circuits

    DOEpatents

    Bright, Arthur A.; Crumley, Paul G.; Dombrowa, Marc B.; Douskey, Steven M.; Haring, Rudolf A.; Oakland, Steven F.; Ouellette, Michael R.; Strissel, Scott A.

    2008-07-08

    Disclosed is a method of repairing an integrated circuit of the type comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The method comprises the steps of providing the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The method comprises the further step of, at a given time, passing the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  19. Method and apparatus for in-system redundant array repair on integrated circuits

    DOEpatents

    Bright, Arthur A.; Crumley, Paul G.; Dombrowa, Marc B.; Douskey, Steven M.; Haring, Rudolf A.; Oakland, Steven F.; Ouellette, Michael R.; Strissel, Scott A.

    2008-07-29

    Disclosed is a method of repairing an integrated circuit of the type comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The method comprises the steps of providing the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The method comprises the further step of, at a given time, passing the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  20. Method and apparatus for in-system redundant array repair on integrated circuits

    DOEpatents

    Bright, Arthur A.; Crumley, Paul G.; Dombrowa, Marc B.; Douskey, Steven M.; Haring, Rudolf A.; Oakland, Steven F.; Ouellette, Michael R.; Strissel, Scott A.

    2007-12-18

    Disclosed is a method of repairing an integrated circuit of the type comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The method comprises the steps of providing the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The method comprises the further step of, at a given time, passing the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  1. Potential inspection, maintenance and repair techniques for the OTEC (Ocean Thermal Energy Conversion) systems

    SciTech Connect

    Not Available

    1983-02-01

    One of the major post-installation considerations of the OTEC platforms is the performance of underwater inspection, maintenance and repair (IMR) during their 30-year design life. In order to assist in the conceptual development of an IMR program, this study was undertaken using the two OTEC candidate configurations as a baseline. The objectives of the study were: (1) conduct an inventory of underwater Non-Destructive Examination (NDE) devices including a description of their performance capabilities, dimensional data, the areas of the various structures where they are most applicable, and a narrative description of the level of performance attained to date; (2) and to conduct an inventory of NDE device deployment vehicles which also includes a description of their performance capabilities, dimensional data, areas of the platform where they are most applicable as now designed and a relative comparison of these vehicles as to their ability to deploy the devices described in (1) above.

  2. Design structure for in-system redundant array repair in integrated circuits

    DOEpatents

    Bright, Arthur A.; Crumley, Paul G.; Dombrowa, Marc; Douskey, Steven M.; Haring, Rudolf A.; Oakland, Steven F.; Quellette, Michael R.; Strissel, Scott A.

    2008-11-25

    A design structure for repairing an integrated circuit during operation of the integrated circuit. The integrated circuit comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The design structure provides the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The design structure further passes the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  3. New directions in mechanics

    DOE PAGES [OSTI]

    Kassner, Michael E.; Nemat-Nasser, Sia; Suo, Zhigang; Bao, Gang; Barbour, J. Charles; Brinson, L. Catherine; Espinosa, Horacio; Gao, Huajian; Granick, Steve; Gumbsch, Peter; et al

    2004-09-15

    The Division of Materials Sciences and Engineering of the US Department of Energy (DOE) sponsored a workshop to identify cutting-edge research needs and opportunities, enabled by the application of theoretical and applied mechanics. The workshop also included input from biochemical, surface science, and computational disciplines, on approaching scientific issues at the nanoscale, and the linkage of atomistic-scale with nano-, meso-, and continuum-scale mechanics. This paper is a summary of the outcome of the workshop, consisting of three main sections, each put together by a team of workshop participants. Section 1 addresses research opportunities that can be realized by the applicationmore » of mechanics fundamentals to the general area of self-assembly, directed self-assembly, and fluidics. Section 2 examines the role of mechanics in biological, bioinspired, and biohybrid material systems, closely relating to and complementing the material covered in Section 1. In this manner, it was made clear that mechanics plays a fundamental role in understanding the biological functions at all scales, in seeking to utilize biology and biological techniques to develop new materials and devices, and in the general area of bionanotechnology. While direct observational investigations are an essential ingredient of new discoveries and will continue to open new exciting research doors, it is the basic need for controlled experimentation and fundamentally- based modeling and computational simulations that will be truly empowered by a systematic use of the fundamentals of mechanics. Section 3 brings into focus new challenging issues in inelastic deformation and fracturing of materials that have emerged as a result of the development of nanodevices, biopolymers, and hybrid bio–abio systems. As a result, each section begins with some introductory overview comments, and then provides illustrative examples that were presented at the workshop and which are believed to highlight the

  4. Creative problem solving at Rocky Reach

    SciTech Connect

    Bickford, B.M.; Garrison, D.H.

    1997-04-01

    Tainter gate inspection and thrust bearing cooling system problems at the 1287-MW Rocky Reach hydroelectric project on the Columbia River in Washington are described. Gate inspection was initiated in response to a failure of similar gates at Folsom Dam. The approach involved measuring the actual forces on the gates and comparing them to original model study parameters, rather than the traditional method of building a hydraulic model. Measurement and visual inspection was completed in one day and had no effect on migration flows. Two problems with the thrust bearing cooling system are described. First, whenever a generating unit was taken off line, cooling water continued circulating and lowered oil temperatures. The second problem involved silt buildup in flow measuring device tubes on the cooling water system. Modifications to correct cooling system problems and associated costs are outlined.

  5. Modeling the black hole excision problem

    SciTech Connect

    Szilagyi, B.; Winicour, J.; Kreiss, H.-O.

    2005-05-15

    We analyze the excision strategy for simulating black holes. The problem is modeled by the propagation of quasilinear waves in a 1-dimensional spatial region with timelike outer boundary, spacelike inner boundary and a horizon in between. Proofs of well-posed evolution and boundary algorithms for a second differential order treatment of the system are given for the separate pieces underlying the finite-difference problem. These are implemented in a numerical code which gives accurate long term simulations of the quasilinear excision problem. Excitation of long wavelength exponential modes, which are latent in the problem, are suppressed using conservation laws for the discretized system. The techniques are designed to apply directly to recent codes for the Einstein equations based upon the harmonic formulation.

  6. Kinetic gating mechanism of DNA damage recognition by Rad4/XPC

    DOE PAGES [OSTI]

    Chen, Xuejing; Velmurugu, Yogambigai; Zheng, Guanqun; Park, Beomseok; Shim, Yoonjung; Kim, Youngchang; Liu, Lili; Van Houten, Bennett; He, Chuan; Ansari, Anjum; et al

    2015-01-06

    The xeroderma pigmentosum C (XPC) complex initiates nucleotide excision repair by recognizing DNA lesions before recruiting downstream factors. How XPC detects structurally diverse lesions embedded within normal DNA is unknown. Here we present a crystal structure that captures the yeast XPC orthologue (Rad4) on a single register of undamaged DNA. The structure shows that a disulphide-tethered Rad4 flips out normal nucleotides and adopts a conformations similar to that seen with damaged DNA. Contrary to many DNA repair enzymes that can directly reject non-target sites as structural misfits, our results suggest that Rad4/XPC uses a kinetic gating mechanism whereby lesion selectivitymore » arises from the kinetic competition between DNA opening and the residence time of Rad4/XPC per site. This mechanism is further supported by measurements of Rad4-induced lesion-opening times using temperature-jump pertubation spectroscopy. Kinetic gating may be a general mechanism used by site-specific DNA-binding proteins to minimize time-consuming interrogations of non-target sites.« less

  7. Frequency Instability Problems in North American Interconnections

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Frequency Instability Problems in North American Interconnections May 1, 2011 DOE/NETL-2011/1473 Frequency Instability Problems in North American Interconnections Disclaimer This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness

  8. VERA Core Physics Benchmark Progression Problems Specifications

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    VERA Core Physics Benchmark Progression Problem Specifications Revision 4 August 29, 2014 Andrew T. Godfrey Physics Integration Oak Ridge National Laboratory CASL-U-2012-0131-004 VERA Core Physics Benchmark Problems Consortium for Advanced Simulation of LWRs ii CASL-U-2012-0131-004 Oak Ridge National Laboratory in partnership with Electric Power Research Institute Idaho National Laboratory Los Alamos National Laboratory Massachusetts Institute of Technology North Carolina State University Sandia

  9. Cancer's big data problem | Argonne National Laboratory

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    You may also like Cancer's big data problem October 19, 2016 Two protein studies discover molecular secrets to recycling carbon and healing cells September 9, 2016 Two Argonne-led projects among $39.8 million in first-round Exascale Computing Project awards September 7, 2016 X-rays reveal the photonic crystals in butterfly wings that create color June 10, 2016 New Microbiome Center to combine UChicago, Marine Biological Laboratory and Argonne expertise May 13, 2016 Cancer's big data problem By

  10. Geological problems in radioactive waste isolation

    SciTech Connect

    Witherspoon, P.A.

    1991-01-01

    The problem of isolating radioactive wastes from the biosphere presents specialists in the fields of earth sciences with some of the most complicated problems they have ever encountered. This is especially true for high level waste (HLW) which must be isolated in the underground and away from the biosphere for thousands of years. Essentially every country that is generating electricity in nuclear power plants is faced with the problem of isolating the radioactive wastes that are produced. The general consensus is that this can be accomplished by selecting an appropriate geologic setting and carefully designing the rock repository. Much new technology is being developed to solve the problems that have been raised and there is a continuing need to publish the results of new developments for the benefit of all concerned. The 28th International Geologic Congress that was held July 9--19, 1989 in Washington, DC provided an opportunity for earth scientists to gather for detailed discussions on these problems. Workshop W3B on the subject, Geological Problems in Radioactive Waste Isolation -- A World Wide Review'' was organized by Paul A Witherspoon and Ghislain de Marsily and convened July 15--16, 1989 Reports from 19 countries have been gathered for this publication. Individual papers have been cataloged separately.

  11. Thick diffusion limit boundary layer test problems

    SciTech Connect

    Bailey, T. S.; Warsa, J. S.; Chang, J. H.; Adams, M. L.

    2013-07-01

    We develop two simple test problems that quantify the behavior of computational transport solutions in the presence of boundary layers that are not resolved by the spatial grid. In particular we study the quantitative effects of 'contamination' terms that, according to previous asymptotic analyses, may have a detrimental effect on the solutions obtained by both discontinuous finite element (DFEM) and characteristic-method (CM) spatial discretizations, at least for boundary layers caused by azimuthally asymmetric incident intensities. Few numerical results have illustrated the effects of this contamination, and none have quantified it to our knowledge. Our test problems use leading-order analytic solutions that should be equal to zero in the problem interior, which means the observed interior solution is the error introduced by the contamination terms. Results from DFEM solutions demonstrate that the contamination terms can cause error propagation into the problem interior for both orthogonal and non-orthogonal grids, and that this error is much worse for non-orthogonal grids. This behavior is consistent with the predictions of previous analyses. We conclude that these boundary layer test problems and their variants are useful tools for the study of errors that are introduced by unresolved boundary layers in diffusive transport problems. (authors)

  12. Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair

    SciTech Connect

    Chen, Xi; Ballin, Jeff D.; Della-Maria, Julie; Tsai, Miaw-Sheue; White, Elizabeth J.; Tomkinson, Alan E.; Wilson, Gerald M.

    2009-05-11

    The three human LIG genes encode polypeptides that catalyze phosphodiester bond formation during DNA replication, recombination and repair. While numerous studies have identified protein partners of the human DNA ligases (hLigs), there has been little characterization of the catalytic properties of these enzymes. In this study, we developed and optimized a fluorescence-based DNA ligation assay to characterize the activities of purified hLigs. Although hLigI joins DNA nicks, it has no detectable activity on linear duplex DNA substrates with short, cohesive single-strand ends. By contrast, hLigIII{beta} and the hLigIII{alpha}/XRCC1 and hLigIV/XRCC4 complexes are active on both nicked and linear duplex DNA substrates. Surprisingly, hLigIV/XRCC4, which is a key component of the major non-homologous end joining (NHEJ) pathway, is significantly less active than hLigIII on a linear duplex DNA substrate. Notably, hLigIV/XRCC4 molecules only catalyze a single ligation event in the absence or presence of ATP. The failure to catalyze subsequent ligation events reflects a defect in the enzyme-adenylation step of the next ligation reaction and suggests that, unless there is an in vivo mechanism to reactivate DNA ligase IV/XRCC4 following phosphodiester bond formation, the cellular NHEJ capacity will be determined by the number of adenylated DNA ligaseIV/XRCC4 molecules.

  13. Sea bed mechanics

    SciTech Connect

    Sleath, J.F.A.

    1984-01-01

    This book provides a discussion on sea bed processes with engineering applications. It brings together the material currently available only in technical reports of research papers. It provides formulae and background references necessary for design calculation of problems such as sea bed or coastal erosion, and sub-marine pipeline stability. It also covers dissipation of wave energy, formation of ripples and dunes, and the transportation of sediments.

  14. Backlash compensator mechanism

    DOEpatents

    Chrislock, Jerry L.

    1979-01-01

    Mechanism which compensates for backlash error in a lead screw position indicator by decoupling the indicator shaft from the lead screw when reversing rotation. The position indicator then displays correct information regardless of the direction of rotation of the lead screw.

  15. Wear-mechanism modelling

    SciTech Connect

    Ashby, M.F. . Dept. of Engineering)

    1993-03-01

    Goals of the program are to calculate the surface temperatures in dry sliding, develop a soft wear tester for ceramics, survey the wear mechanisms in brittle solids, and couple the temperature calculations with models to give wear maps for brittle solids. (DLC)

  16. Residential Mechanical Precooling

    SciTech Connect

    German, a.; Hoeschele, M.

    2014-12-01

    This research conducted by the Alliance for Residential Building Innovation team evaluated mechanical air conditioner pre-cooling strategies in homes throughout the United States. EnergyPlus modeling evaluated two homes with different performance characteristics in seven climates. Results are applicable to new construction homes and most existing homes built in the last 10 years, as well as fairly efficient retrofitted homes.

  17. DYNA3D example problem manual

    SciTech Connect

    Lovejoy, S.C.; Whirley, R.G.

    1990-10-10

    This manual describes in detail the solution of ten example problems using the explicit nonlinear finite element code DYNA3D. The sample problems include solid, shell, and beam element types, and a variety of linear and nonlinear material models. For each example, there is first an engineering description of the physical problem to be studied. Next, the analytical techniques incorporated in the model are discussed and key features of DYNA3D are highlighted. INGRID commands used to generate the mesh are listed, and sample plots from the DYNA3D analysis are given. Finally, there is a description of the TAURUS post-processing commands used to generate the plots of the solution. This set of example problems is useful in verifying the installation of DYNA3D on a new computer system. In addition, these documented analyses illustrate the application of DYNA3D to a variety of engineering problems, and thus this manual should be helpful to new analysts getting started with DYNA3D. 7 refs., 56 figs., 9 tabs.

  18. Particle physics confronts the solar neutrino problem

    SciTech Connect

    Pal, P.B.

    1991-06-01

    This review has four parts. In Part I, we describe the reactions that produce neutrinos in the sun and the expected flux of those neutrinos on the earth. We then discuss the detection of these neutrinos, and how the results obtained differ from the theoretical expectations, leading to what is known as the solar neutrino problem. In Part II, we show how neutrino oscillations can provide a solution to the solar neutrino problem. This includes vacuum oscillations, as well as matter enhanced oscillations. In Part III, we discuss the possibility of time variation of the neutrino flux and how a magnetic moment of the neutrino can solve the problem. WE also discuss particle physics models which can give rise to the required values of magnetic moments. In Part IV, we present some concluding remarks and outlook for the recent future.

  19. MOLECULAR MECHANISM OF SUPPRESSION OF NEOPLASTIC TRANSFORMATION BY LOW DOSES OF LOW LET RADIATION

    SciTech Connect

    J.LESIE REDPATH, PH.D.

    2011-03-29

    We are currently funded (9/01-8/04) by the DOE Low Dose Radiation Research Program to examine mechanisms underlying the suppression of neoplastic transformation in vitro by low doses of low LET radiation. For the new studies proposed under Notice 04-21, we intend to follow up on our observation that upregulation of DNA repair may be an important factor and that its importance is dose-dependent. The experimental system will be the human hybrid cell neoplastic transformation assay that we are currently using. We propose to test the following hypothesis: Down-regulation of DNA dsb repair will abrogate the low dose suppression of neoplastic transformation. Using the technique of RNA silencing, it is proposed to test the effect of down-regulation of the two major DNA dsb repair pathways, homologous recombination (HR) and non-homologous end-joining (NHEJ), on the dose response relationship for neoplastic transformation. Based on prior studies, we predict that this will result in abrogation of the suppressive effect at doses in the range 1 to 10 cGy, but not at lower doses. The proposed experiments will also help address the question as to which of the two DNA repair pathways may be the most important in causing suppression of transformation. HR is a pathway that is predominant in S and G2 phase cells and is known to be less error-prone than the NHEJ pathway that is predominant in G1 phase. We hypothesize that down-regulation of HR will result in the most effective abrogation of suppression. An important component of this study will be the determination of the how abrogation of DNA dsb repair impacts the spontaneous transformation frequency, presumably a consequence of endogeneous DNA damage. Experiments will be carried out using partially synchronized populations of cells enriched for G1 and S/G2 respectively. In addition to the endpoint of neoplastic transformation the impact of down-regulation of HR and NHEJ on the formation and disappearance of the DNA dsb marker

  20. Transport Test Problems for Hybrid Methods Development

    SciTech Connect

    Shaver, Mark W.; Miller, Erin A.; Wittman, Richard S.; McDonald, Benjamin S.

    2011-12-28

    This report presents 9 test problems to guide testing and development of hybrid calculations for the ADVANTG code at ORNL. These test cases can be used for comparing different types of radiation transport calculations, as well as for guiding the development of variance reduction methods. Cases are drawn primarily from existing or previous calculations with a preference for cases which include experimental data, or otherwise have results with a high level of confidence, are non-sensitive, and represent problem sets of interest to NA-22.

  1. MECHANICS OF CRACK BRIDGING UNDER DYNAMIC LOADS

    SciTech Connect

    N. SRIDHAR; ET AL

    2001-02-01

    A bridging law for fiber reinforced composites under dynamic crack propagation conditions has been derived. Inertial effects in the mechanism of fiber pullout during dynamic propagation of a bridged crack are critically examined for the first time. By reposing simple shear lag models of pullout as problems of dynamic wave propagation, the effect of the frictional coupling between the fibers and the matrix is accounted for in a fairly straightforward way. The solutions yield the time-dependent relationship between the crack opening displacement and the bridging traction. Engineering criteria and the role of material and geometrical parameters for significant inertial effects are identified.

  2. Unique Auxin Regulation Mechanism Discovered

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Unique Auxin Regulation Mechanism Discovered Print Wednesday, 29 August 2007 00:00 The plant hormone auxin regulates many plant growth ...

  3. NUT SCREW MECHANISMS

    DOEpatents

    Glass, J.A.F.

    1958-07-01

    A reactor control mechanism is described wherein the control is achieved by the partial or total withdrawal of the fissile material which is in the form of a fuel rod. The fuel rod is designed to be raised and lowered from the reactor core area by means of two concentric ball nut and screw assemblies that may telescope one within the other. These screw mechanisms are connected through a magnetic clutch to a speed reduction gear and an accurately controllable prime motive source. With the clutch energized, the fuel rod may be moved into the reactor core area, and fine adjustments may be made through the reduction gearing. However, in the event of a power failure or an emergency signal, the magnetic clutch will become deenergized, and the fuel rod will drop out of the core area by the force of gravity, thus shutting down the operation of the reactor.

  4. Automation of mechanical testing

    SciTech Connect

    Heberling, D.T.

    1993-01-01

    This publication, Automation of Mechanical Testing, contains papers presented at the symposium of the same name, held in Pittsburgh, PA on 21 May 1992. The symposium was sponsored by ASTM Committee E-28 on Mechanical Testing. David T. Heberling, Armco Steel Co., L.P., Middletown Works Metallurgical Laboratory, Middletown, OH, presided as symposium chairman and is editor of the resulting publication. Hopefully, the initial flurry of activity has now subsided enough that the 90s can be a decade of maturing and standardization of automated test procedures. To help achieve this goal, the authors present in this STP nine technical papers on the automation of mechanical testing. The first five form a primer for those preparing to implement automated testing. These papers consist of information obtained the hard way--from experience with automation projects. Beginning with the fifth, which fits into both categories, the papers focus on specific technical issues and topics, many of which affect or need to be addressed by ASTM standards.

  5. Motor operated valves problems tests and simulations

    SciTech Connect

    Pinier, D.; Haas, J.L.

    1996-12-01

    An analysis of the two refusals of operation of the EAS recirculation shutoff valves enabled two distinct problems to be identified on the motorized valves: the calculation methods for the operating torques of valves in use in the power plants are not conservative enough, which results in the misadjustement of the torque limiters installed on their motorizations, the second problem concerns the pressure locking phenomenon: a number of valves may entrap a pressure exceeding the in-line pressure between the disks, which may cause a jamming of the valve. EDF has made the following approach to settle the first problem: determination of the friction coefficients and the efficiency of the valve and its actuator through general and specific tests and models, definition of a new calculation method. In order to solve the second problem, EDF has made the following operations: identification of the valves whose technology enables the pressure to be entrapped: the tests and numerical simulations carried out in the Research and Development Division confirm the possibility of a {open_quotes}boiler{close_quotes} effect: determination of the necessary modifications: development and testing of anti-boiler effect systems.

  6. The scattering problem for nonlocal potentials

    SciTech Connect

    Zolotarev, V A

    2014-11-30

    We solve the direct and inverse scattering problems for integro-differential operators which are one-dimensional perturbations of the self-adjoint second derivative operator on the half-axis. We also describe the scattering data for this class of operators. Bibliography: 28 titles.

  7. Solving the problems of infectious waste disposal

    SciTech Connect

    Hoffman, S.L.; Cabral, N.J. )

    1989-06-01

    Lawmakers are increasing pressures to ensure safe, appropriate disposal of infectious waste. This article discusses the problems, the regulatory climate, innovative approaches, and how to pay for them. The paper discusses the regulatory definition of infectious waste, federal and state regulations, and project finance.

  8. Quasivelocities and Optimal Control for underactuated Mechanical Systems

    SciTech Connect

    Colombo, L.; Martin de Diego, D.

    2010-07-28

    This paper is concerned with the application of the theory of quasivelocities for optimal control for underactuated mechanical systems. Using this theory, we convert the original problem in a variational second-order lagrangian system subjected to constraints. The equations of motion are geometrically derived using an adaptation of the classical Skinner and Rusk formalism.

  9. STUDY OF THE RHIC BPM SMA CONNECTOR FAILURE PROBLEM

    SciTech Connect

    LIAW,C.; SIKORA, R.; SCHROEDER, R.

    2007-06-25

    About 730 BPMs are mounted on the RHIC CQS and Triplet super-conducting magnets. Semi-rigid coaxial cables are used to bring the electrical signal from the BPM feedthroughs to the outside flanges. at the ambient temperature. Every year around 10 cables will lose their signals during the operation. The connection usually failed at the warm end of the cable. The problems were either the solder joint failed or the center conductor retracted out of the SMA connector. Finite element analyses were performed to understand the failure mechanism of the solder joint. The results showed that (1) The SMA center conductor can separate from the mating connector due to the thermal retraction. (2) The maximum thermal stress at the warm end solder joint can exceed the material strength of the Pb37/Sn63 solder material and (3) The magnet ramping frequency (-10 Hz), during the machine startup, can possibly resonant the coaxial cable and damage the solder joints, especially when a fracture is initiated. Test results confirmed that by using the silver bearing solder material (a higher strength material) and by crimping the cable at the locations close to the SMA connector (to prevent the center conductor from retracting) can effectively resolve the connector failure problem.

  10. Phosphoramide mustard exposure induces DNA adduct formation and the DNA damage repair response in rat ovarian granulosa cells

    SciTech Connect

    Ganesan, Shanthi Keating, Aileen F.

    2015-02-01

    Phosphoramide mustard (PM), the ovotoxic metabolite of the anti-cancer agent cyclophosphamide (CPA), destroys rapidly dividing cells by forming NOR-G-OH, NOR-G and G-NOR-G adducts with DNA, potentially leading to DNA damage. A previous study demonstrated that PM induces ovarian DNA damage in rat ovaries. To investigate whether PM induces DNA adduct formation, DNA damage and induction of the DNA repair response, rat spontaneously immortalized granulosa cells (SIGCs) were treated with vehicle control (1% DMSO) or PM (3 or 6 μM) for 24 or 48 h. Cell viability was reduced (P < 0.05) after 48 h of exposure to 3 or 6 μM PM. The NOR-G-OH DNA adduct was detected after 24 h of 6 μM PM exposure, while the more cytotoxic G-NOR-G DNA adduct was formed after 48 h by exposure to both PM concentrations. Phosphorylated H2AX (γH2AX), a marker of DNA double stranded break occurrence, was also increased by PM exposure, coincident with DNA adduct formation. Additionally, induction of genes (Atm, Parp1, Prkdc, Xrcc6, and Brca1) and proteins (ATM, γH2AX, PARP-1, PRKDC, XRCC6, and BRCA1) involved in DNA repair were observed in both a time- and dose-dependent manner. These data support that PM induces DNA adduct formation in ovarian granulosa cells, induces DNA damage and elicits the ovarian DNA repair response. - Highlights: • PM forms ovarian DNA adducts. • DNA damage marker γH2AX increased by PM exposure. • PM induces ovarian DNA double strand break repair.

  11. Sac Angiography and Glue Embolization in Emergency Endovascular Aneurysm Repair for Ruptured Abdominal Aortic Aneurysm

    SciTech Connect

    Koike, Yuya Nishimura, Jun-ichi Hase, Soichiro Yamasaki, Motoshige

    2015-04-15

    PurposeThe purpose of this study was to demonstrate a sac angiography technique and evaluate the feasibility of N-butyl cyanoacrylate (NBCA) embolization of the ruptured abdominal aortic aneurysm (AAA) sac in emergency endovascular aneurysm repair (EVAR) in hemodynamically unstable patients.MethodsA retrospective case series of three patients in whom sac angiography was performed during emergency EVAR for ruptured AAA was reviewed. After stent graft deployment, angiography within the sac of aneurysm (sac angiography) was performed by manually injecting 10 ml of contrast material through a catheter to identify the presence and site of active bleeding. In two patients, sac angiography revealed active extravasation of the contrast material, and NBCA embolization with a coaxial catheter system was performed to achieve prompt sealing.ResultsSac angiography was successful in all three patients. In the two patients who underwent NBCA embolization for aneurysm sac bleeding, follow-up computed tomography (CT) images demonstrated the accumulation of NBCA consistent with the bleeding site in preprocedural CT images.ConclusionsEVAR is associated with a potential risk of ongoing bleeding from type II or IV endoleaks into the disrupted aneurysm sac in patients with severe coagulopathy. Therefore, sac angiography and NBCA embolization during emergency EVAR may represent a possible technical improvement in the treatment of ruptured AAA in hemodynamically unstable patients.

  12. Sierra/solid mechanics 4.22 user's guide.

    SciTech Connect

    Thomas, Jesse David

    2011-10-01

    Sierra/SolidMechanics (Sierra/SM) is a Lagrangian, three-dimensional code for the analysis of solids and structures. It provides capabilities for explicit dynamic and implicit quasistatic and dynamic analyses. The explicit dynamics capabilities allow for the efficient and robust solution of models subjected to large, suddenly applied loads. For implicit problems, Sierra/SM uses a multi-level iterative solver, which enables it to effectively solve problems with large deformations, nonlinear material behavior, and contact. Sierra/SM has a versatile library of continuum and structural elements, and an extensive library of material models. The code is written for parallel computing environments, and it allows for scalable solutions of very large problems for both implicit and explicit analyses. It is built on the SIERRA Framework, which allows for coupling with other SIERRA mechanics codes. This document describes the functionality and input structure for Sierra/SM.

  13. PSM`s most common struggle: Implementing mechanical integrity

    SciTech Connect

    Remson, A.C.; Farmer, J.H.; King, S.C. [JBF Associates, Inc., Knoxville, TN (United States)] [JBF Associates, Inc., Knoxville, TN (United States)

    1995-10-01

    Most companies have found that of the 14 OSHA PSM elements, Mechanical Integrity (MI) presents the greatest implementation challenge. Although maintenance departments have successfully installed, repaired, and replaced plant equipment for decades, many of these same maintenance departments have struggled with OSHA`s PSM requirements. One major challenge is prioritizing resources. Opportunities to improve will always exist; however, it is often difficult to effectively allocate money and manpower. Another challenge is simply getting organized. The MI program should be supported by appropriate, useful procedures; but given the multifaceted and ever-changing nature of maintenance, what procedures should be written? How detailed should be procedures be? With nearly 3 years of PSM enforcement complete, an analysis of OSHA`s MI citation helps to provide insight to these challenges. This paper presents ideas for implementing MI in a manner that meets OSHA`s expectations while contributing to safe, effective maintenance in PSM-covered processes. In particular, the paper presents ideas for developing MI programs that effectively prioritize company resources, with appropriate inspection/test/preventive maintenance and quality assurance (QA) activities. This paper also presents ideas for developing a list of mechanical integrity procedures to address OSHA`s requirements as well as the type of information to include in those procedures. 10 refs., 3 tabs.

  14. Homologous recombination and non-homologous end-joining repair pathways in bovine embryos with different developmental competence

    SciTech Connect

    Henrique Barreta, Marcos; Laboratorio de Biotecnologia e Reproducao Animal-BioRep, Universidade Federal de Santa Maria, Santa Maria, RS ; Garziera Gasperin, Bernardo; Braga Rissi, Vitor; Cesaro, Matheus Pedrotti de; Ferreira, Rogerio; Oliveira, Joao Francisco de; Goncalves, Paulo Bayard Dias; Bordignon, Vilceu

    2012-10-01

    This study investigated the expression of genes controlling homologous recombination (HR), and non-homologous end-joining (NHEJ) DNA-repair pathways in bovine embryos of different developmental potential. It also evaluated whether bovine embryos can respond to DNA double-strand breaks (DSBs) induced with ultraviolet irradiation by regulating expression of genes involved in HR and NHEJ repair pathways. Embryos with high, intermediate or low developmental competence were selected based on the cleavage time after in vitro insemination and were removed from in vitro culture before (36 h), during (72 h) and after (96 h) the expected period of embryonic genome activation. All studied genes were expressed before, during and after the genome activation period regardless the developmental competence of the embryos. Higher mRNA expression of 53BP1 and RAD52 was found before genome activation in embryos with low developmental competence. Expression of 53BP1, RAD51 and KU70 was downregulated at 72 h and upregulated at 168 h post-insemination in response to DSBs induced by ultraviolet irradiation. In conclusion, important genes controlling HR and NHEJ DNA-repair pathways are expressed in bovine embryos, however genes participating in these pathways are only regulated after the period of embryo genome activation in response to ultraviolet-induced DSBs.

  15. Algebraic techniques for diagonalization of a split quaternion matrix in split quaternionic mechanics

    SciTech Connect

    Jiang, Tongsong; Jiang, Ziwu; Zhang, Zhaozhong

    2015-08-15

    In the study of the relation between complexified classical and non-Hermitian quantum mechanics, physicists found that there are links to quaternionic and split quaternionic mechanics, and this leads to the possibility of employing algebraic techniques of split quaternions to tackle some problems in complexified classical and quantum mechanics. This paper, by means of real representation of a split quaternion matrix, studies the problem of diagonalization of a split quaternion matrix and gives algebraic techniques for diagonalization of split quaternion matrices in split quaternionic mechanics.

  16. Drill drive mechanism

    DOEpatents

    Dressel, Michael O.

    1979-01-01

    A drill drive mechanism is especially adapted to provide both rotational drive and axial feed for a drill of substantial diameter such as may be used for drilling holes for roof bolts in mine shafts. The drill shaft is made with a helical pattern of scroll-like projections on its surface for removal of cuttings. The drill drive mechanism includes a plurality of sprockets carrying two chains of drive links which are arranged to interlock around the drill shaft with each drive link having depressions which mate with the scroll-like projections. As the chain links move upwardly or downwardly the surfaces of the depressions in the links mate with the scroll projections to move the shaft axially. Tangs on the drive links mate with notch surfaces between scroll projections to provide a means for rotating the shaft. Projections on the drive links mate together at the center to hold the drive links tightly around the drill shaft. The entire chain drive mechanism is rotated around the drill shaft axis by means of a hydraulic motor and gear drive to cause rotation of the drill shaft. This gear drive also connects with a differential gearset which is interconnected with a second gear. A second motor is connected to the spider shaft of the differential gearset to produce differential movement (speeds) at the output gears of the differential gearset. This differential in speed is utilized to drive said second gear at a speed different from the speed of said gear drive, this speed differential being utilized to drive said sprockets for axial movement of said drill shaft.

  17. Fracture mechanics: 26. volume

    SciTech Connect

    Reuter, W.G.; Underwood, J.H.; Newman, J.C. Jr.

    1995-12-31

    The original objective of these symposia was to promote technical interchange between researchers from the US and worldwide in the field of fracture. This objective was recently expanded to promote technical interchange between researchers in the field of fatigue and fracture. The symposium began with the Swedlow Memorial Lecture entitled ``Patterns and Perspectives in Applied Fracture Mechanics.`` The remaining 42 papers are divided into the following topical sections: Constraint crack initiation; Constraint crack growth; Weldments; Engineered materials; Subcritical crack growth; Dynamic loading; and Applications. Papers within the scope of the Energy Data Base have been processed separately.

  18. Heavy crudes, stocks pose desalting problems

    SciTech Connect

    Bartley, D.

    1982-02-02

    The design of electrostatic desalters for crudes lighter than 30 API is well established and is no longer considered a problem. However, since 1970, the number of desalting applications involving heavy crudes (less than 20 API), syncrudes, and residual fuels has increased markedly. These stocks present unique problems that require additional design considerations. All produced crude oils, including synthetic crude from shale, tar sands, and coal liquefaction, contain impurities that adversely affect production and refining processes, the equipment used in these processes, and the final products. The most common of these impurities are water, salt, solids, metals, and sulfur. The desalting process consists of (1) adding water with a low salt content (preferably fresh) to the feedstock; (2) adequately mixing this added water with the feedstock, which already contains some quantities of salty water, sediment, and/or crystalline salt; and (3) extracting as much water as possible from the feedstock.

  19. Aleph Field Solver Challenge Problem Results Summary.

    SciTech Connect

    Hooper, Russell; Moore, Stan Gerald

    2015-01-01

    Aleph models continuum electrostatic and steady and transient thermal fields using a finite-element method. Much work has gone into expanding the core solver capability to support enriched mod- eling consisting of multiple interacting fields, special boundary conditions and two-way interfacial coupling with particles modeled using Aleph's complementary particle-in-cell capability. This report provides quantitative evidence for correct implementation of Aleph's field solver via order- of-convergence assessments on a collection of problems of increasing complexity. It is intended to provide Aleph with a pedigree and to establish a basis for confidence in results for more challeng- ing problems important to Sandia's mission that Aleph was specifically designed to address.

  20. Scalable Adaptive Multilevel Solvers for Multiphysics Problems

    SciTech Connect

    Xu, Jinchao

    2014-12-01

    In this project, we investigated adaptive, parallel, and multilevel methods for numerical modeling of various real-world applications, including Magnetohydrodynamics (MHD), complex fluids, Electromagnetism, Navier-Stokes equations, and reservoir simulation. First, we have designed improved mathematical models and numerical discretizaitons for viscoelastic fluids and MHD. Second, we have derived new a posteriori error estimators and extended the applicability of adaptivity to various problems. Third, we have developed multilevel solvers for solving scalar partial differential equations (PDEs) as well as coupled systems of PDEs, especially on unstructured grids. Moreover, we have integrated the study between adaptive method and multilevel methods, and made significant efforts and advances in adaptive multilevel methods of the multi-physics problems.

  1. Residential Mechanical Precooling

    SciTech Connect

    German, Alea; Hoeschele, Marc

    2014-12-01

    Residential air conditioning (AC) represents a challenging load for many electric utilities with poor load factors. Mechanical precooling improves the load factor by shifting cooling operation from on-peak to off-peak hours. This provides benefits to utilities and the electricity grid, as well as to occupants who can take advantage of time-of-use (TOU) electricity rates. Performance benefits stem from reduced compressor cycling, and shifting condensing unit operation to earlier periods of the day when outdoor temperatures are more favorable to operational efficiency. Finding solutions that save energy and reduce demand on the electricity grid is an important national objective and supports key Building America goals. The Alliance for Residential Building Innovation team evaluated mechanical AC precooling strategies in homes throughout the United States. EnergyPlus modeling was used to evaluate two homes with different performance characteristics in seven climates. Results are applicable to new construction homes and most existing homes built in the last 10 years, as well as fairly efficient retrofitted homes. A successful off-peak AC strategy offers the potential for increased efficiency and improved occupant comfort, and promotes a more reliable and robust electricity grid. Demand response capabilities and further integration with photovoltaic TOU generation patterns provide additional opportunities to flatten loads and optimize grid impacts.

  2. Repair of radiation-induced heat-labile sites is independent of DNA-PKcs, XRCC1 or PARP

    SciTech Connect

    Stenerlw, Bo; Karlsson, Karin H.; Radulescu, Irina; Rydberg, Bjorn; Stenerlow, Bo

    2008-04-29

    Ionizing radiation induces a variety of different DNA lesions: in addition to the most critical DNA damage, the DSB, numerous base alterations, SSBs and other modifications of the DNA double-helix are formed. When several non-DSB lesions are clustered within a short distance along DNA, or close to a DSB, they may interfere with the repair of DSBs and affect the measurement of DSB induction and repair. We have previously shown that a substantial fraction of DSBs measured by pulsed-field gel electrophoresis (PFGE) are in fact due to heat-labile sites (HLS) within clustered lesions, thus reflecting an artifact of preparation of genomic DNA at elevated temperature. To further characterize the influence of HLS on DSB induction and repair, four human cell lines (GM5758, GM7166, M059K, U-1810) with apparently normal DSB rejoining were tested for bi-phasic rejoining after gamma irradiation. When heat-released DSBs were excluded from the measurements the fraction of fast rejoining decreased to less than 50% of the total. However, neither the half-times of the fast (t{sub 1/2} = 7-8 min) or slow (t{sub 1/2} = 2.5 h) DSB rejoining were changed significantly. At t=0 the heat-released DSBs accounted for almost 40% of the DSBs, corresponding to 10 extra DSB/cell/Gy in the initial DSB yield. These heat-released DSBs were repaired within 60-90 min in all tested cells, including M059K cells treated with wortmannin or DNA-PKcs defect M059J cells. Furthermore, cells lacking XRCC1 or Poly(ADP-ribose) polymerase-1 (PARP-1) rejoined both total DSBs and heat-released DSBs similar to normal cells. In summary, the presence of heat-labile sites have a substantial impact on DSB induction yields and DSB rejoining rates measured by pulsed-field gel electrophoresis, and HLS repair is independent of DNA-PKcs, XRCC1 and PARP.

  3. Ergonomics problems and solutions in biotechnology laboratories

    SciTech Connect

    Coward, T.W.; Stengel, J.W.; Fellingham-Gilbert, P.

    1995-03-01

    The multi-functional successful ergonomics program currently implemented at Lawrence Livermore National Laboratory (LLNL) will be presented with special emphasis on recent findings in the Biotechnology laboratory environment. In addition to a discussion of more traditional computer-related repetitive stress injuries and associated statistics, the presentation will cover identification of ergonomic problems in laboratory functions such as pipetting, radiation shielding, and microscope work. Techniques to alleviate symptoms and prevent future injuries will be presented.

  4. Are shorted pipeline casings a problem

    SciTech Connect

    Gibson, W.F. )

    1994-11-01

    The pipeline industry has many road and railroad crossings with casings which have been in service for more than 50 years without exhibiting any major problems, regardless of whether the casing is shorted to or isolated from the carrier pipe. The use of smart pigging and continual visual inspection when retrieving a cased pipeline segment have shown that whether shorted or isolated, casings have no significant bearing on the presence or absence of corrosion on the carrier pipe.

  5. Diabaticity of nuclear motion: problems and perspectives

    SciTech Connect

    Nazarewicz, W [Joint Inst. for Heavy Ion Research, Oak Ridge, TN (United States)] [Joint Inst. for Heavy Ion Research, Oak Ridge, TN (United States)

    1992-12-31

    The assumption of adiabatic motion lies in foundations of many models of nuclear collective motion. To what extend can nuclear modes be treated adiabatically? Due to the richness and complexity of the nuclear many-body problem there is no unique answer to this question. The challenges of nuclear collective dynamics invite exciting interactions between several areas of physics such as nuclear structure, field theory, nonlinear dynamics, transport theory, and quantum chaos.

  6. CMI Grand Challenge Problems | Critical Materials Institute

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    CMI Grand Challenge Problems Time is the biggest issue. Materials typically become critical in a matter of months, but solutions take years or decades to develop and implement. Our first two grand challenges address this discrepancy. Anticipating Which Materials May Go Critical In an ideal world, users of materials would anticipate supply-chain disruptions before they occur. They would undertake activities to manage the risks of disruption, including R&D to diversify and increase supplies or

  7. Hierarchical optimization for neutron scattering problems

    DOE PAGES [OSTI]

    Bao, Feng; Archibald, Rick; Bansal, Dipanshu; Delaire, Olivier

    2016-03-14

    In this study, we present a scalable optimization method for neutron scattering problems that determines confidence regions of simulation parameters in lattice dynamics models used to fit neutron scattering data for crystalline solids. The method uses physics-based hierarchical dimension reduction in both the computational simulation domain and the parameter space. We demonstrate for silicon that after a few iterations the method converges to parameters values (interatomic force-constants) computed with density functional theory simulations.

  8. RELAP5-3D User Problems

    SciTech Connect

    Riemke, Richard Allan

    2001-09-01

    The Reactor Excursion and Leak Analysis Program with 3D capability1 (RELAP5-3D) is a reactor system analysis code that has been developed at the Idaho National Engineering and Environmental Laboratory (INEEL) for the U. S. Department of Energy (DOE). The 3D capability in RELAP5-3D includes 3D hydrodynamics2 and 3D neutron kinetics3,4. Assessment, verification, and validation of the 3D capability in RELAP5-3D is discussed in the literature5,6,7,8,9. Additional assessment, verification, and validation of the 3D capability of RELAP5-3D will be presented in other papers in this users seminar. As with any software, user problems occur. User problems usually fall into the categories of input processing failure, code execution failure, restart/renodalization failure, unphysical result, and installation. This presentation will discuss some of the more generic user problems that have been reported on RELAP5-3D as well as their resolution.

  9. RELAP5-3D User Problems

    SciTech Connect

    Riemke, Richard Allan

    2002-09-01

    The Reactor Excursion and Leak Analysis Program with 3D capability1 (RELAP5-3D) is a reactor system analysis code that has been developed at the Idaho National Engineering and Environmental Laboratory (INEEL) for the U. S. Department of Energy (DOE). The 3D capability in RELAP5-3D includes 3D hydrodynamics2 and 3D neutron kinetics3,4. Assessment, verification, and validation of the 3D capability in RELAP5-3D is discussed in the literature5,6,7,8,9,10. Additional assessment, verification, and validation of the 3D capability of RELAP5-3D will be presented in other papers in this users seminar. As with any software, user problems occur. User problems usually fall into the categories of input processing failure, code execution failure, restart/renodalization failure, unphysical result, and installation. This presentation will discuss some of the more generic user problems that have been reported on RELAP5-3D as well as their resolution.

  10. Exact Overlaps in the Kondo Problem (Journal Article) | DOE PAGES

    Office of Scientific and Technical Information (OSTI)

    Exact Overlaps in the Kondo Problem Prev Next Title: Exact Overlaps in the Kondo Problem Authors: Lukyanov, Sergei L. ; Saleur, Hubert ; Jacobsen, Jesper L. ; Vasseur, Romain ...

  11. Statistics Show Bearing Problems Cause the Majority of Wind Turbine...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Statistics Show Bearing Problems Cause the Majority of Wind Turbine Gearbox Failures Statistics Show Bearing Problems Cause the Majority of Wind Turbine Gearbox Failures September ...

  12. Solving a Class of Nonlinear Eigenvalue Problems by Newton's...

    Office of Scientific and Technical Information (OSTI)

    We examine the possibility of using the standard Newton's method for solving a class of ... NONLINEAR PROBLEMS nonlinear eigenvalue problem, Newton's method Word Cloud More Like ...

  13. Problems with propagation and time evolution in f ( T ) gravity...

    Office of Scientific and Technical Information (OSTI)

    Problems with propagation and time evolution in f ( T ) gravity Citation Details In-Document Search Title: Problems with propagation and time evolution in f ( T ) gravity Authors: ...

  14. Data integration reveals key homeostatic mechanisms following low dose radiation exposure

    SciTech Connect

    Tilton, Susan C.; Matzke, Melissa M.; Sowa, Marianne B.; Stenoien, David L.; Weber, Thomas J.; Morgan, William F.; Waters, Katrina M.

    2015-05-15

    The goal of this study was to define pathways regulated by low dose radiation to understand how biological systems respond to subtle perturbations in their environment and prioritize pathways for human health assessment. Using an in vitro 3-D human full thickness skin model, we have examined the temporal response of dermal and epidermal layers to 10 cGy X-ray using transcriptomic, proteomic, phosphoproteomic and metabolomic platforms. Bioinformatics analysis of each dataset independently revealed potential signaling mechanisms affected by low dose radiation, and integrating data shed additional insight into the mechanisms regulating low dose responses in human tissue. We examined direct interactions among datasets (top down approach) and defined several hubs as significant regulators, including transcription factors (YY1, MYC and CREB1), kinases (CDK2, PLK1) and a protease (MMP2). These data indicate a shift in response across time — with an increase in DNA repair, tissue remodeling and repression of cell proliferation acutely (24–72 h). Pathway-based integration (bottom up approach) identified common molecular and pathway responses to low dose radiation, including oxidative stress, nitric oxide signaling and transcriptional regulation through the SP1 factor that would not have been identified by the individual data sets. Significant regulation of key downstream metabolites of nitrative stress was measured within these pathways. Among the features identified in our study, the regulation of MMP2 and SP1 was experimentally validated. Our results demonstrate the advantage of data integration to broadly define the pathways and networks that represent the mechanisms by which complex biological systems respond to perturbation. - Highlights: • Low dose ionizing radiation altered homeostasis in 3D skin tissue model. • Global gene/protein/metabolite data integrated using complementary statistical approaches • Time and location-specific change in matrix regulation

  15. Fundamental Study of the Mechanical Strength Degradation Mechanisms of PFSA

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Membranes and MEAs | Department of Energy Fundamental Study of the Mechanical Strength Degradation Mechanisms of PFSA Membranes and MEAs Fundamental Study of the Mechanical Strength Degradation Mechanisms of PFSA Membranes and MEAs Presentation at the 2008 High Temperature Membrane Working Group Meeting held June 9, 2008, in Washington, DC huang_htmwg_2008.pdf (2.27 MB) More Documents & Publications Membrane Durability in PEM Fuel Cells: Chemical Degradation Automotive Perspective on PEM

  16. Rotary drive mechanism

    SciTech Connect

    Kenderdine, E.W.

    1991-10-08

    This patent describes a rotary drive mechanism which includes a rotary solenoid having a stator and multi-poled rotor. A moving member rotates with the rotor and is biased by a biasing device. The biasing device causes a further rotational movement after rotation by the rotary solenoid. Thus, energization of the rotary solenoid moves the member in one direction to one position and biases the biasing device against the member. Subsequently, de- energization of the rotary solenoid causes the biasing device to move the member in the same direction to another position from where the moving member is again movable by energization and de-energization of the rotary solenoid. Preferably, the moving member is a multi-lobed cam having the same number of lobes as the rotor has poles. An anti- overdrive device is also preferably provided for preventing overdrive in the forward direction or a reverse rotation of the moving member and for precisely aligning the moving member.

  17. PEBBLES Mechanics Simulation Speedup

    SciTech Connect

    Joshua J. Cogliati; Abderrafi M. Ougouag

    2010-05-01

    Pebble bed reactors contain large numbers of spherical fuel elements arranged randomly. Determining the motion and location of these fuel elements is required for calculating certain parameters of pebble bed reactor operation. These simulations involve hundreds of thousands of pebbles and involve determining the entire core motion as pebbles are recirculated. Single processor algorithms for this are insufficient since they would take decades to centuries of wall-clock time. This paper describes the process of parallelizing and speeding up the PEBBLES pebble mechanics simulation code. Both shared memory programming with the Open Multi-Processing API and distributed memory programming with the Message Passing Interface API are used in simultaneously in this process. A new shared memory lock-less linear time collision detection algorithm is described. This method allows faster detection of pebbles in contact than generic methods. These combine to make full recirculations on AVR sized reactors possible in months of wall clock time.

  18. Altitude release mechanism

    DOEpatents

    Kulhanek, Frank C.

    1977-01-01

    An altitude release mechanism for releasing a radiosonde or other measuring instrument from a balloon carrying it up into the atmosphere includes a bottle partially filled with water, a tube sealed into the bottle having one end submerged in the water in the bottle and the free end extending above the top of the bottle and a strip of water-disintegrable paper held within the free end of the tube linking the balloon to the remainder of the package. As the balloon ascends, the lowered atmospheric air pressure causes the air in the bottle to expand, forcing the water in the bottle up the tubing to wet and disintegrate the paper, releasing the package from the balloon.

  19. Mechanically expandable annular seal

    DOEpatents

    Gilmore, Richard F.

    1983-01-01

    A mechanically expandable annular reusable seal assembly to form an annular hermetic barrier between two stationary, parallel, and planar containment surfaces. A rotatable ring, attached to the first surface, has ring wedges resembling the saw-tooth array of a hole saw. Matching seal wedges are slidably attached to the ring wedges and have their motion restricted to be perpendicular to the second surface. Each seal wedge has a face parallel to the second surface. An annular elastomer seal has a central annular region attached to the seal wedges' parallel faces and has its inner and outer circumferences attached to the first surface. A rotation of the ring extends the elastomer seal's central region perpendicularly towards the second surface to create the fluidtight barrier. A counterrotation removes the barrier.

  20. Mechanically expandable annular seal

    DOEpatents

    Gilmore, R.F.

    1983-07-19

    A mechanically expandable annular reusable seal assembly to form an annular hermetic barrier between two stationary, parallel, and planar containment surfaces is described. A rotatable ring, attached to the first surface, has ring wedges resembling the saw-tooth array of a hole saw. Matching seal wedges are slidably attached to the ring wedges and have their motion restricted to be perpendicular to the second surface. Each seal wedge has a face parallel to the second surface. An annular elastomer seal has a central annular region attached to the seal wedges' parallel faces and has its inner and outer circumferences attached to the first surface. A rotation of the ring extends the elastomer seal's central region perpendicularly towards the second surface to create the fluid tight barrier. A counter rotation removes the barrier. 6 figs.

  1. Rotary drive mechanism

    DOEpatents

    Kenderdine, Eugene W. (Albuquerque, NM)

    1991-01-01

    A rotary drive mechanism includes a rotary solenoid having a stator and multi-poled rotor. A moving member rotates with the rotor and is biased by a biasing device. The biasing device causes a further rotational movement after rotation by the rotary solenoid. Thus, energization of the rotary solenoid moves the member in one direction to one position and biases the biasing device against the member. Subsequently, de-energization of the rotary solenoid causes the biasing device to move the member in the same direction to another position from where the moving member is again movable by energization and de-energization of the rotary solenoid. Preferably, the moving member is a multi-lobed cam having the same number of lobes as the rotor has poles. An anti-overdrive device is also preferably provided for preventing overdrive in the forward direction or a reverse rotation of the moving member and for precisely aligning the moving member.

  2. Large Diameter Limbs for Dilated Common Iliac Arteries in Endovascular Aneurysm Repair. Is It Safe?

    SciTech Connect

    Malagari, Katerina Brountzos, Elias; Gougoulakis, Alexandros; Papathanasiou, Matilda; Alexopoulou, Efthymia; Mastorakou, Renata; Kelekis, Dimitris

    2004-09-15

    In this prospective study we examined whether dilated common iliac arteries (CIAs) can provide a safe distal seal in endovascular aneurysm repair (EVAR) with the use of bifurcated stent grafts with large diameter limbs. Sixteen patients with 26 dilated CIAs with a diameter of {>=}6 mm who were offered EVAR using stent grafts with large diameter limbs were included in the study (Group A). Forty-two patients who also underwent EVAR without iliac dilatation, matched for age, sex and surgical risk were used for comparison (controls-Group B). In group A mean CIA diameter was 18.2 mm (16-28) and mean abdominal aortic aneurysm (AAA) diameter was 6.87 {+-} 1.05 cm; mean age was 77.2 {+-} 4.8 yrs (67-81). Mean follow-up was 33.6 months (2.8 yrs). CIA diameter changes and development of endoleaks were assessed by CT angiography (CTA). Overall iliac dilatation was present in 16/58 of our patients (27.6%). In 10 patients dilatation was bilateral (17.3%). Partial or complete flow to the internal iliac artery (IIA) territories was preserved in all patients post-EVAR. On follow-up, stable caliber of the dilated CIAs was observed in 21 patients (84%), enlargement of 1mm in 3 (16%), and failure of the distal attachment in 1 (6.2%). Compared to the control group there was no statistical significance in the incidence of complications. Dilated common iliac arteries provide a safe distal seal in patients who have undergone EVAR, thus obviating the need for additional endovascular procedures and sparing flow in the IIA vascular bed.

  3. Design, build, develop and test a fieldworthy spiral tool and packer for casing repair

    SciTech Connect

    Koster, C.

    1993-01-01

    A new method for sealing casing is under research and development by Nu-Bore Systems. The method involves internally lining a section of the wellbore with a multi-layer spiral wrapping of a high strength, corrosion resistant metal interleaved with a high bond strength, resilient epoxy. The high strength metal is preferably a copper based alloy hardened to a very high strength in order to resist the internal and external pressures of downhole environments. The epoxy adhesive formulation is one that forms a bond between the steel inner wall of the casing and copper alloy strip. The copper alloy strip spiral wraps are interleaved with epoxy, and the whole system provides a high level of outward directed spring force and, thus, resists both internal and externally directed forces. In this report, the cost savings to the nation's energy program was estimated to be in the range of hundreds of millions of dollars per year, and the method was judged technically feasible once certain well defined engineering obstacles are Overcome. The objective of this program is to develop a joint between packer segments that is easily assembled before lowering downhole and easily disassembled after the sealing job is done. In addition, this tool joint must expand uniformly as though it were a part of the rubber and must not fail under the relatively high pressure of the epoxy cure cycle. The overall goal of the work was to design, build, develop, and test a spiral tool and packer into a single universal tool that can repair casings with diameters varying from 4.5 to 7 inches.

  4. Identification of Intrinsic Order and Disorder in the DNA Repair Protein XPA

    SciTech Connect

    Iakoucheva, Lilia M.; Kimzey, Amy L.; Masselon, Christophe D.; Bruce, James E.; Garner, Ethan C.; Brown, Celeste J.; Dunker, A. K.; Smith, Richard D.; Ackerman, Eric J.

    2001-03-01

    The damage recognition protein XPA is required to recognize a wide variety of bulky lesions during nucleotide excision repair (NER). Independent NMR solution structures of a human XPA protein (hXPA) fragment comprising approximately one-third of the full-length protein, the minimal DNA-binding domain (MBD), revealed that ~30% of the molecule was structurally disordered. To better characterize structural features of XPA, we performed time-resolved trypsin proteolysis on active, full-length recombinant Xenopus XPA protein (xXPA). The resulting proteolytic fragments were analyzed by electrospray ionization interface coupled to a Fourier transform ion cyclotron resonance (ESI-FTICR) mass spectrometry, SDS-polyacrylamide gel electrophoresis (PAGE), and selected N-terminal sequence determinations. The mass spectrum of the full-length xXPA was consistent with the predicted sequence, 30922.02 vs. 30922.45 Da; respectively. Moreover, the mass spectrometric data allowed the assignment of multiple xXPA fragments not resolvable by SDS PAGE. Full-length xXPA exhibited aberrant mobility on SDS-PAGE with an apparent MW of ~40 kDa. To test predictions that a Glu-rich region (E70-E76) or other local regions of high charge were responsible for this ~40% aberrant SDS-PAGE mobility, the MW's of partial proteolytic fragments from ~5 to 25 kDa precisely determined by ESI-FTICR MS were correlated with their gel positions. Surprisingly, all tested partial tryptic fragments within this size-range exhibited 10-42% divergence between calculated MW and that estimated by SDS-PAGE, thus indicating the origin of anomalous migration of XPA is not localized. The computer program Predictor of Natural Disordered Regions (PONDR) correctly identified several regions of xXPA either sensitive or resistant to partial proteolysis, thereby indicating that disorder in XPA shares sequence features with other well-characterized intrinsically unstructured proteins.

  5. ZRBA1, a Mixed EGFR/DNA Targeting Molecule, Potentiates Radiation Response Through Delayed DNA Damage Repair Process in a Triple Negative Breast Cancer Model

    SciTech Connect

    Heravi, Mitra; Kumala, Slawomir; Rachid, Zakaria; Jean-Claude, Bertrand J.; Radzioch, Danuta; Muanza, Thierry M.

    2015-06-01

    Purpose: ZRBA1 is a combi-molecule designed to induce DNA alkylating lesions and to block epidermal growth factor receptor (EGFR) TK domain. Inasmuch as ZRBA1 downregulates the EGFR TK-mediated antisurvival signaling and induces DNA damage, we postulated that it might be a radiosensitizer. The aim of this study was to further investigate the potentiating effect of ZRBA1 in combination with radiation and to elucidate the possible mechanisms of interaction between these 2 treatment modalities. Methods and Materials: The triple negative human breast MDA-MB-468 cancer cell line and mouse mammary cancer 4T1 cell line were used in this study. Clonogenic assay, Western blot analysis, and DNA damage analysis were performed at multiple time points after treatment. To confirm our in vitro findings, in vivo tumor growth delay assay was performed. Results: Our results show that a combination of ZRBA1 and radiation increases the radiation sensitivity of both cell lines significantly with a dose enhancement factor of 1.56, induces significant numbers of DNA strand breaks, prolongs higher DNA damage up to 24 hours after treatment, and significantly increases tumor growth delay in a syngeneic mouse model. Conclusions: Our data suggest that the higher efficacy of this combination could be partially due to increased DNA damage and delayed DNA repair process and to the inhibition of EGFR. The encouraging results of this combination demonstrated a significant improvement in treatment efficiency and therefore could be applicable in early clinical trial settings.

  6. Studies in nonlinear problems of energy

    SciTech Connect

    Matkowsky, B.J.

    1992-07-01

    Emphasis has been on combustion and flame propagation. The research program was on modeling, analysis and computation of combustion phenomena, with emphasis on transition from laminar to turbulent combustion. Nonlinear dynamics and pattern formation were investigated in the transition. Stability of combustion waves, and transitions to complex waves are described. Combustion waves possess large activation energies, so that chemical reactions are significant only in thin layers, or reaction zones. In limit of infinite activation energy, the zones shrink to moving surfaces, (fronts) which must be found during the analysis, so that (moving free boundary problems). The studies are carried out for limiting case with fronts, while the numerical studies are carried out for finite, though large, activation energy. Accurate resolution of the solution in the reaction zones is essential, otherwise false predictions of dynamics are possible. Since the the reaction zones move, adaptive pseudo-spectral methods were developed. The approach is based on a synergism of analytical and computational methods. The numerical computations build on and extend the analytical information. Furthermore, analytical solutions serve as benchmarks for testing the accuracy of the computation. Finally, ideas from analysis (singular perturbation theory) have induced new approaches to computations. The computational results suggest new analysis to be considered. Among the recent interesting results, was spatio-temporal chaos in combustion. One goal is extension of the adaptive pseudo-spectral methods to adaptive domain decomposition methods. Efforts have begun to develop such methods for problems with multiple reaction zones, corresponding to problems with more complex, and more realistic chemistry. Other topics included stochastics, oscillators, Rysteretic Josephson junctions, DC SQUID, Markov jumps, laser with saturable absorber, chemical physics, Brownian movement, combustion synthesis, etc.

  7. PCI Capability Development and Challenge Problem Progress

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    6-000 PCI Capability Development and Challenge Problem Progress Joe Rashid 1 , Brian D. Wirth 2 , Rich Williamson 3 1 ANATECH Corp 2 University of Tennessee 3 Idaho National Laboratory 2 CASL-U-2016-1086-000 Outline * State of the art of PCI & Fuel Performance Codes (FPCs) * FPCs compatibility with Utilities needs - what are the gaps? Can BISON close these gaps? * PCI Capability Development: BISON progress to-date * BISON as a Phase-2 product - will it fulfill its promise? 3

  8. Bile Duct Disruption Following Radiofrequency Ablation: Successful Repair Using a Covered Stent

    SciTech Connect

    Thompson, Philip M.; Hare, Christopher M.B. Lees, William R.

    2004-08-15

    Persistent biliary leaks, whether iatrogenic or secondary to malignancy, often present a difficult management problem. Recent reports have suggested a role for covered metallic stents in this context. We describe the successful use of a covered stent to seal a persistent biliary leak following radiofrequency ablation of colorectal liver metastases.

  9. Public problems: Still waiting on the marketplace for solutions

    SciTech Connect

    Gover, J.; Carayannis, E.; Huray, P.

    1997-10-01

    This report addresses the need for government sponsored R and D to address real public problems. The motivation is that a public benefit of the money spent must be demonstrated. The areas identified as not having appropriate attention resulting in unmet public needs include healthcare cost, cost and benefits of regulations, infrastructure problems, defense spending misaligned with foreign policy objectives, the crime problem, energy impact on the environment, the education problem, low productivity growth industry sectors, the income distribution problem, the aging problem, the propagation of disease and policy changes needed to address the solution of these problems.

  10. DYNA3D Non-reflecting Boundary Conditions - Test Problems

    SciTech Connect

    Zywicz, E

    2006-09-28

    Two verification problems were developed to test non-reflecting boundary segments in DYNA3D (Whirley and Engelmann, 1993). The problems simulate 1-D wave propagation in a semi-infinite rod using a finite length rod and non-reflecting boundary conditions. One problem examines pure pressure wave propagation, and the other problem explores pure shear wave propagation. In both problems the non-reflecting boundary segments yield results that differ only slightly (less than 6%) during a short duration from their corresponding theoretical solutions. The errors appear to be due to the inability to generate a true step-function compressive wave in the pressure wave propagation problem and due to segment integration inaccuracies in the shear wave propagation problem. These problems serve as verification problems and as regression test problems for DYNA3D.

  11. The proton storage ring: Problems and solutions

    SciTech Connect

    Macek, R.J.

    1988-01-01

    The Los Alamos Proton Storage Ring (PSR) now operates with 35..mu..A at 20-Hz pulse repetition rate. Beam availability during 1988 suffered because of a number of problems with hardware reliability and from narrow operating margins for beam spill in the extraction line. A strong effort is underway to improve reliability with an eventual goal of obtaining beam availability in excess of 75%. Beam losses and the resulting component activation have limited operating currents to their present values. In detailed studies of the problem, loss rates were found to be approximately proportional to the circulating current and can be understood by a detailed accounting of emittance growth in the two-step injection process along with Coulomb scattering of the stored beam during multiple traversals of the injection foil. It is now apparent that the key to reducing losses is in reducing the number of foil traversals. A program of upgrades to reduce losses and improve the operating current is being planned. 8 refs., 17 figs., 2 tabs.

  12. Engineering problems of tandem-mirror reactors

    SciTech Connect

    Moir, R.W.; Barr, W.L.; Boghosian, B.M.

    1981-10-22

    We have completed a comparative evaluation of several end plug configurations for tandem mirror fusion reactors with thermal barriers. The axi-cell configuration has been selected for further study and will be the basis for a detailed conceptual design study to be carried out over the next two years. The axi-cell end plug has a simple mirror cell produced by two circular coils followed by a transition coil and a yin-yang pair, which provides for MHD stability. This paper discusses some of the many engineering problems facing the designer. We estimated the direct cost to be 2$/W/sub e/. Assuming total (direct and indirect) costs to be twice this number, we need to reduce total costs by factors between 1.7 and 2.3 to compete with future LWRs levelized cost of electricity. These reductions may be possible by designing magnets producing over 20T made possible by use of combinations of superconducting and normal conducting coils as well as improvements in performance and cost of neutral beam and microwave power systems. Scientific and technological understanding and innovation are needed in the area of thermal barrier pumping - a process by which unwanted particles are removed (pumped) from certain regions of velocity and real space in the end plug. Removal of exhaust fuel ions, fusion ash and impurities by action of a halo plasma and plasma dump in the mirror end region is another challenging engineering problem discussed in this paper.

  13. The PHEV Charging Infrastructure Planning (PCIP) Problem

    SciTech Connect

    Dashora, Yogesh; Barnes, J. Wesley; Pillai, Rekha S; Combs, Todd E; Hilliard, Michael R; Chinthavali, Madhu Sudhan

    2010-01-01

    Increasing debates over a gasoline independent future and the reduction of greenhouse gas (GHG) emissions has led to a surge in plug-in hybrid electric vehicles (PHEVs) being developed around the world. The majority of PHEV related research has been directed at improving engine and battery operations, studying future PHEV impacts on the grid, and projecting future PHEV charging infrastructure requirements. Due to the limited all-electric range of PHEVs, a daytime PHEV charging infrastructure will be required for most PHEV daily usage. In this paper, for the first time, we present a mixed integer mathematical programming model to solve the PHEV charging infrastructure planning (PCIP) problem for organizations with thousands of people working within a defined geographic location and parking lots well suited to charging station installations. Our case study, based on the Oak Ridge National Laboratory (ORNL) campus, produced encouraging results, indicates the viability of the modeling approach and substantiates the importance of considering both employee convenience and appropriate grid connections in the PCIP problem.

  14. New Technologies for Repairing Aging Cables in Nuclear Power Plants: M3LW-14OR0404015 Cable Rejuvenation Report

    SciTech Connect

    Simmons, Kevin L.; Fifield, Leonard S.; Westman, Matthew P.; Roberts, John A.

    2014-09-08

    The goal of this project is to conceptually demonstrate techniques to repair cables that have degraded through subjection to long-term thermal and radiation exposure in nuclear power plants. In fiscal year 2014 (FY14) we focused on commercially available ethylene-propylene rubber (EPR) as the relevant test material, isolated a high surface area form of the EPR material to facilitate chemical treatment screening and charaterization, and measured chemical changes in the material due to aging and treatment using Fourier Transfrom Infrared (FTIR) spectroscopy.

  15. Environmental Assessment and Finding of No Significant Impact: Pond B Dam Repair Project at the Savannah River Site

    SciTech Connect

    N /A

    1999-09-27

    The Department of Energy (DOE) has prepared an environmental assessment (EA) (DOE/EA-1285) for the proposed repair of the Pond B dam at the Savannah River Site (SRS), located near Aiken, South Carolina. Based on the analyses in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 (NEPA). Therefore, the preparation of an environmental impact statement (EIS) is not required, and DOE is issuing this Finding of No Significant Impact (FONSI) and Floodplain Statement of Findings.

  16. Permafrost problems as they affect gas pipelines (the frost heave problem)

    SciTech Connect

    Lipsett, G.B.

    1980-01-01

    The major problems associated with the construction of a large diameter gas pipeline in a permafrost region are outlined in this presentation. Data pertains to the design and construction of the Alaska Highway Gas Pipeline Project. One of the main problems is maintaining the permafrost in its frozen state. Large diameter pipelines operating at high capacity are heat generators. Therefore, it is necessary to refrigerate the gas to ensure that it remains below 0/sup 0/C at all points in the pipeline system. The pipeline also passes through unfrozen ground where the potential for frost heave exists. The conditions under which frost heave occurs are listed. The extent and location of potential frost heave problem areas must be determined and a frost heave prediction method must be established before construction begins. Another task involves development of design criteria for the pipeline/soil interaction analysis. Remedial methods for use during the operational phase are also discussed. (DMC)

  17. Evaluating the integrity of the reinforced concrete structure repaired by epoxy injection using simulated transfer function of impact-echo response

    SciTech Connect

    Cheng, Chia-Chi; Yu, Chih-peng; Wu, Jiunn-Hong; Hsu, Keng-Tsan; Ke, Ying-Tsu

    2014-02-18

    Cracks and honeycombs are often found inside reinforced concrete (RC) structure caused by excessive external force, or improper casting of concrete. The repairing method usually involves epoxy injection. The impact-echo method, which is a sensitive for detecting of the interior voids, may not be applicable to assess the integrity of the repaired member as both air and epoxy are less in acoustic impedances. In this study, the repaired RC structure was evaluated by the simulated transfer function of the IE displacement waveform where the R-wave displacement waveform is used as a base of a simulated force-time function. The effect of different thickness of the epoxy layer to the amplitude corresponding to the interface is studied by testing on specimen containing repaired naturally delaminated cracks with crack widths about 1 mm, 3 mm and 5 mm. The impact-echo responses were compared with the drilling cores at the test positions. The results showed the cracks were not fully filled with epoxy when the peak amplitude corresponding to the interface dropped less than 20%. The peak corresponding to the thicker epoxy layer tends to be larger in amplitude. A field study was also performed on a column damaged by earthquake before and after repairing.

  18. MECHANICAL SYSTEMS - MULTIFAMILY: Venting | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    MECHANICAL SYSTEMS - MULTIFAMILY: Venting MECHANICAL SYSTEMS - MULTIFAMILY: Venting 5_venting.zip (2.87 MB) More Documents & Publications MECHANICAL SYSTEMS - MULTIFAMILY: Combustion MECHANICAL SYSTEMS - MULTIFAMILY: Building as a System MECHANICAL SYSTEMS - MULTIFAMILY: Steam System Piping

  19. Municipal solid waste (garbage): problems and benefits

    SciTech Connect

    Stillman, G.I.

    1983-05-01

    The average person in the USA generates from 3 1/2 to 7 lb of garbage/day. The combustible portion of garbage consists primarily of paper products, plastics, textiles, and wood. Problems connected with energy production from municipal solid waste (garbage), and the social, economic, and environmental factors associated with this technology are discussed. The methods for using garbage as a fuel for a combustion process are discussed. One method processes the garbage to produce a fuel that is superior to raw garbage, the other method of using garbage as a fuel is to burn it directly - the mass burning approach. The involvement of the Power Authority of the State of New York in garbage-to-energy technology is discussed.

  20. Relative locality and the soccer ball problem

    SciTech Connect

    Amelino-Camelia, Giovanni; Freidel, Laurent; Smolin, Lee; Kowalski-Glikman, Jerzy

    2011-10-15

    We consider the behavior of macroscopic bodies within the framework of relative locality [G. Amelino-Camelia, L. Freidel, J. Kowalski-Glikman, and L. Smolin, arXiv:1101.0931]. This is a recent proposal for Planck scale modifications of the relativistic dynamics of particles which are described as arising from deformations in the geometry of momentum space. We consider and resolve a common objection against such proposals, which is that, even if the corrections are small for elementary particles in current experiments, they are huge when applied to composite systems such as soccer balls, planets, and stars, with energies E{sub macro} much larger than M{sub P}. We show that this soccer ball problem does not arise within the framework of relative locality because the nonlinear effects for the dynamics of a composite system with N elementary particles appear at most of order E{sub macro}/N{center_dot}M{sub P}.

  1. New tools attack Permian basin stimulation problems

    SciTech Connect

    Ely, J.W.; Schubarth, S.K.; Wolters, B.C.; Kromer, C. )

    1992-06-08

    This paper reports that profitable stimulation treatments in the Permian basin of the southwestern U.S. combine new tools with technology and fluids previously available. This paper reports that a wide selection of fracturing fluids and techniques needs to be considered to solve the varied problems associated with stimulating hydrocarbon reservoirs that are at diverse depths, temperatures, pressures, and lithologies. The Permian basin of West Texas and New Mexico is the most fertile ground in the U.S. for some of the newer stimulation technologies. In this basin, these new tools and techniques have been applied in many older producing areas that previously were treated with more conventional stimulation techniques, including acidizing and conventional fracturing procedures.

  2. Stochastic inverse problems: Models and metrics

    SciTech Connect

    Sabbagh, Elias H.; Sabbagh, Harold A.; Murphy, R. Kim; Aldrin, John C.; Annis, Charles; Knopp, Jeremy S.

    2015-03-31

    In past work, we introduced model-based inverse methods, and applied them to problems in which the anomaly could be reasonably modeled by simple canonical shapes, such as rectangular solids. In these cases the parameters to be inverted would be length, width and height, as well as the occasional probe lift-off or rotation. We are now developing a formulation that allows more flexibility in modeling complex flaws. The idea consists of expanding the flaw in a sequence of basis functions, and then solving for the expansion coefficients of this sequence, which are modeled as independent random variables, uniformly distributed over their range of values. There are a number of applications of such modeling: 1. Connected cracks and multiple half-moons, which we have noted in a POD set. Ideally we would like to distinguish connected cracks from one long shallow crack. 2. Cracks of irregular profile and shape which have appeared in cold work holes during bolt-hole eddy-current inspection. One side of such cracks is much deeper than other. 3. L or C shaped crack profiles at the surface, examples of which have been seen in bolt-hole cracks. By formulating problems in a stochastic sense, we are able to leverage the stochastic global optimization algorithms in NLSE, which is resident in VIC-3D®, to answer questions of global minimization and to compute confidence bounds using the sensitivity coefficient that we get from NLSE. We will also address the issue of surrogate functions which are used during the inversion process, and how they contribute to the quality of the estimation of the bounds.

  3. LAMPF transition-region mechanical fabrication

    SciTech Connect

    Bush, E.D. Jr.; Gallegos, J.D.F.; Harrison, R.; Hart, V.E.; Hunter, W.T.; Rislove, S.E.; Sims, J.R.; Van Dyke, W.J.

    1984-07-01

    The primary purpose of the new Transition Region (TR-II) is to optimize the phase matching of the H/sup +/ and H/sup -/ beams during simultaneous transport. TR-II incorporates several design improvements that include larger aperture, a straight beam track, greater beam-path length adjustments, and utility lines integrated with the support system. The close pack density of magnets and beam-line hardware required innovative solutions to magnet design and mounting, vacuum manifolding, and utility routing. Critical magnet placement was accomplished using a new three-dimensional alignment system that does real-time vector calculations on a computer with input from two digital theodolites. All assembly and a large fraction of the mechanical fabrication were done by LAMPF personnel. The TR-II has been operational since September 1983 and routinely transports production beams up to 900-..mu..A current with no major problems.

  4. Fill fouling experiences on both mechanical and natural draft towers

    SciTech Connect

    Fraze, R.O. )

    1992-01-01

    Fouling of the film fill in cooling towers is becoming an increasingly serious problem in the Utility Industry. This paper discusses Florida Power Corporation's experience with fouling of film type fill in two mechanical draft and two natural draft towers. The two mechanical draft towers were placed in service as helper towers at the Anclote Plant in 1981. The two natural draft towers went into service at the Crystal River North Site in 1982 and 1984 for closed cycle cooling. All the towers are on salt water systems.

  5. A modified Lax-Phillips scattering theory for quantum mechanics

    SciTech Connect

    Strauss, Y.

    2015-07-15

    The Lax-Phillips scattering theory is an appealing abstract framework for the analysis of scattering resonances. Quantum mechanical adaptations of the theory have been proposed. However, since these quantum adaptations essentially retain the original structure of the theory, assuming the existence of incoming and outgoing subspaces for the evolution and requiring the spectrum of the generator of evolution to be unbounded from below, their range of applications is rather limited. In this paper, it is shown that if we replace the assumption regarding the existence of incoming and outgoing subspaces by the assumption of the existence of Lyapunov operators for the quantum evolution (the existence of which has been proved for certain classes of quantum mechanical scattering problems), then it is possible to construct a structure analogous to the Lax-Phillips structure for scattering problems for which the spectrum of the generator of evolution is bounded from below.

  6. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect

    Ruben A. Abagyan, PhD

    2004-04-15

    OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. the authors have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR and R process. The significant achievements of this project include: (1) Construction of the computational pipeline for searching DDR and R genes, building and validation of 3D models of proteins involved in DDR and R; (2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; (3) Important improvement of macromolecular docking technology and its application to predict the DNA-Protein complex conformation; (4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; (5) Construction and maintenance of the DNA Damage Recognition and Repair Database; and (6) Producing 14 research papers (10 published and 4 in preparation).

  7. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect

    Abagyan, Ruben; An, Jianghong

    2005-08-12

    DNA Damage Recognition and Repair (DDR&R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. We have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR&R process. The significant achievements of this project include: 1) Construction of the computational pipeline for searching DDR&R genes, building and validation of 3D models of proteins involved in DDR&R; 2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; and the development of a method to predict the effects of mutations. Large scale testing of technology to identify novel small binding pockets in protein structures leading to new DDRR inhibitor strategies 3) Improvements of macromolecular docking technology (see the CAPRI 1-3 and 4-5 results) 4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; 5) Construction and maintenance of the DNA Damage Recognition and Repair Database; 6) Producing 15 research papers (12 published and 3 in preparation).

  8. Mechanical Behavior of Indium Nanostructures

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    12.3.2 to investigate the small-scale mechanics of indium nanostructures. Scanning x-ray microdiffraction (SXRD) studies revealed that the indium microstructure is typical...

  9. INL '@work' heavy equipment mechanic

    ScienceCinema

    Christensen, Cad

    2013-05-28

    INL's Cad Christensen is a heavy equipment mechanic. For more information about INL careers, visit http://www.facebook.com/idahonationallaboratory.

  10. INL '@work' heavy equipment mechanic

    SciTech Connect

    Christensen, Cad

    2008-01-01

    INL's Cad Christensen is a heavy equipment mechanic. For more information about INL careers, visit http://www.facebook.com/idahonationallaboratory.

  11. Fluid Dynamics and Solid Mechanics

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    ADTSC T T-3 Fluid Dynamics and Solid Mechanics Basic and applied research in theoretical continuum dynamics, modern hydrodynamic theory, materials modeling, global climate ...

  12. Mechanical Behavior of Indium Nanostructures

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Mechanical Behavior of Indium Nanostructures Print Indium is a key material in lead-free solder applications for microelectronics due to its excellent wetting properties, extended...

  13. Unique Auxin Regulation Mechanism Discovered

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ...

  14. Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis

    SciTech Connect

    Dong, Hui; Shi, Qiong; Song, Xiufang; Fu, Juanli; Hu, Lihua; Xu, Demei; Su, Chuanyang; Xia, Xiaomin; Song, Erqun; Song, Yang

    2015-07-01

    Our previous studies demonstrated that polychlorinated biphenyl (PCB) quinone induced oxidative DNA damage in HepG2 cells. To promote genomic integrity, DNA damage response (DDR) coordinates cell-cycle transitions, DNA repair and apoptosis. PCB quinone-induced cell cycle arrest and apoptosis have been documented, however, whether PCB quinone insult induce DNA repair signaling is still unknown. In this study, we identified the activation of DDR and corresponding signaling events in HepG2 cells upon the exposure to a synthetic PCB quinone, PCB29-pQ. Our data illustrated that PCB29-pQ induces the phosphorylation of p53, which was mediated by ataxia telangiectasia mutated (ATM) protein kinase. The observed phosphorylated histone H2AX (γ-H2AX) foci and the elevation of 8-hydroxy-2′-deoxyguanosine (8-OHdG) indicated that DDR was stimulated by PCB29-pQ treatment. Additionally, we found PCB29-pQ activates non-homologous end joining (NHEJ), base excision repair (BER) and nucleotide excision repair (NER) signalings. However, these repair pathways are not error-free processes and aberrant repair of DNA damage may cause the potential risk of carcinogenesis and mutagenesis. - Highlights: • Polychlorinated biphenyl quinone induces oxidative DNA damage in HepG2 cells. • The elevation of γ-H2AX and 8-OHdG indicates the activation of DNA damage response. • ATM-p53 signaling acts as the DNA damage sensor and effector. • Polychlorinated biphenyl quinone activates NHEJ, BER and NER signalings.

  15. Deepwater pipelay prospects prompt study of mechanical connectors

    SciTech Connect

    True, W.R.

    1996-05-06

    A joint industry project to study mechanical connectors for pipeline construction will issue results to its participants next month. Although the study addresses mechanical connector`s use in any environment, connectors are being looked at by offshore operators as a means to minimize pipeline-installation costs, especially in deepwater. The joint industry project, dubbed Low Cost Pipeline Connection Systems, does not compare available connectors but was initiated to specify criteria that operators can use to qualify connectors for use. The project was organized and is now being managed by Hunting Oilfield Services, Aberdeen. Secondarily, the project aims for the following: to develop a clear design premise; to address relevant installation and service issues such as corrosion protection, installation methods, and repair methods, and costing models; to develop specifications and acceptance criteria for the testing of pipeline connectors, this will parallel the ISO specifications and API recommended practices for the testing of downhole connectors; to prove the adequacy of the specifications and criteria by analytical validation methods and in particular by testing programs that simulate, with adequate margins of safety, the installation and service loads on pipeline connectors; to establish and prove, as far as possible, a standardized approach to the testing of pipeline connector systems. That the study is being carried out at all indicates the growth in nonwelded approaches to pipeline construction and reflects industry`s efforts to hold down construction costs, especially for offshore. Yearly, labor costs exceed 45% of pipeline construction costs, as reported in Oil and Gas Journal`s annual Pipeline Economic Reports. This paper reviews the project goals and progress in the areas of research.

  16. Open problems in condensed matter physics, 1987 (Conference)...

    Office of Scientific and Technical Information (OSTI)

    Conference: Open problems in condensed matter physics, 1987 Citation Details In-Document Search Title: Open problems in condensed matter physics, 1987 The 1970's and 1980's can be ...

  17. Fundamental Scientific Problems in Magnetic Recording

    SciTech Connect

    Schulthess, T.C.; Miller, M.K.

    2007-06-27

    Magnetic data storage technology is presently leading the high tech industry in advancing device integration--doubling the storage density every 12 months. To continue these advancements and to achieve terra bit per inch squared recording densities, new approaches to store and access data will be needed in about 3-5 years. In this project, collaboration between Oak Ridge National Laboratory (ORNL), Center for Materials for Information Technology (MINT) at University of Alabama (UA), Imago Scientific Instruments, and Seagate Technologies, was undertaken to address the fundamental scientific problems confronted by the industry in meeting the upcoming challenges. The areas that were the focus of this study were to: (1) develop atom probe tomography for atomic scale imaging of magnetic heterostructures used in magnetic data storage technology; (2) develop a first principles based tools for the study of exchange bias aimed at finding new anti-ferromagnetic materials to reduce the thickness of the pinning layer in the read head; (3) develop high moment magnetic materials and tools to study magnetic switching in nanostructures aimed at developing improved writers of high anisotropy magnetic storage media.

  18. Mechanical properties of reconstituted Australian black coal

    SciTech Connect

    Jasinge, D.; Ranjith, P.G.; Choi, S.K.; Kodikara, J.; Arthur, M.; Li, H.

    2009-07-15

    Coal is usually highly heterogeneous. Great variation in properties can exist among samples obtained even at close proximity within the same seam or within the same core sample. This makes it difficult to establish a correlation between uniaxial compressive strength (UCS) and point load index for coal. To overcome this problem, a method for making reconstituted samples for laboratory tests was developed. Samples were made by compacting particles of crushed coal mixed with cement and water. These samples were allowed to cure for four days. UCS and point load tests were performed to measure the geomechanical properties of the reconstituted coal. After four days curing, the average UCS was found to be approximately 4 MPa. This technical note outlines some experimental results and correlations that were developed to predict the mechanical properties of the reconstituted black coal samples. By reconstituting the samples from crushed coal, it is hoped that the samples will retain the important mechanical and physicochemical properties of coal, including the swelling, fluid transport, and gas sorption properties of coal. The aim is to be able to produce samples that are homogeneous with properties that are highly reproducible, and the reconstituted coal samples can be used for a number of research areas related to coal, including the long-term safe storage of CO{sub 2} in coal seams.

  19. A stochastic mechanism of electron heating

    SciTech Connect

    Galinsky, V. L.; Shevchenko, V. I.

    2012-08-15

    Due to Landau resonant interaction with lower hybrid waves in the lower hybrid current drive scheme part of electrons are accelerated and, as a result of this, a tail of energetic electrons is formed on the electron distribution function. The same situation takes place in the problem of type III radio bursts when the suprathermal burst electrons acquire a plateau distribution due to excitation of plasma waves in the solar wind plasma. These distributions are unstable with respect to the cyclotron excitation of waves at anomalous Doppler resonance ('fan' instability). In this case, the tail electrons interact simultaneously with both (i) waves that accelerate or decelerate them (Cerenkov resonance) and (ii) waves excited in the process of the fan instability that led to their pitch angle diffusion. Because velocity diffusion lines of electrons formed due to heir interaction with each type of waves intersect, this interaction can lead not only to pitch angle diffusion but also to heating of electrons mainly in perpendicular direction. We investigated this mechanism of electron heating and studied the temporal evolution of the electron temperature and the energy of excited waves. Our results show significant enhancement of the electron perpendicular temperature T{sub Up-Tack} due to this stochastic heating mechanism.

  20. The Vainshtein mechanism in the cosmic web

    SciTech Connect

    Falck, Bridget; Koyama, Kazuya; Zhao, Gong-bo; Li, Baojiu E-mail: kazuya.koyama@port.ac.uk E-mail: baojiu.li@durham.ac.uk

    2014-07-01

    We investigate the dependence of the Vainshtein screening mechanism on the cosmic web morphology of both dark matter particles and halos as determined by ORIGAMI. Unlike chameleon and symmetron screening, which come into effect in regions of high density, Vainshtein screening instead depends on the dimensionality of the system, and screened bodies can still feel external fields. ORIGAMI is well-suited to this problem because it defines morphologies according to the dimensionality of the collapsing structure and does not depend on a smoothing scale or density threshold parameter. We find that halo particles are screened while filament, wall, and void particles are unscreened, and this is independent of the particle density. However, after separating halos according to their large scale cosmic web environment, we find no difference in the screening properties of halos in filaments versus halos in clusters. We find that the fifth force enhancement of dark matter particles in halos is greatest well outside the virial radius. We confirm the theoretical expectation that even if the internal field is suppressed by the Vainshtein mechanism, the object still feels the fifth force generated by the external fields, by measuring peculiar velocities and velocity dispersions of halos. Finally, we investigate the morphology and gravity model dependence of halo spins, concentrations, and shapes.

  1. Open problems in condensed matter physics, 1987 (Conference)...

    Office of Scientific and Technical Information (OSTI)

    MAGNETIC FIELDS; METASTABLE STATES; NONLINEAR PROBLEMS; ELECTRIC CONDUCTIVITY; ELECTRICAL PROPERTIES; ENERGY LEVELS; EXCITED STATES; PHYSICAL PROPERTIES; PHYSICS; ...

  2. QUANTUM MECHANICS WITHOUT STATISTICAL POSTULATES

    SciTech Connect

    G. GEIGER; ET AL

    2000-11-01

    The Bohmian formulation of quantum mechanics describes the measurement process in an intuitive way without a reduction postulate. Due to the chaotic motion of the hidden classical particle all statistical features of quantum mechanics during a sequence of repeated measurements can be derived in the framework of a deterministic single system theory.

  3. Possible problems in ENDF/B-VI.r8

    SciTech Connect

    Brown, D; Hedstrom, G

    2003-10-30

    This document lists the problems that we encountered in processing ENDF/B-VI.r8 that we suspect are problems with ENDF/B-VI.r8 itself. It also contains a comparison of linear interpolation methods. Finally, this documents proposes an alternative to the current scheme of reporting problems to the ENDF community.

  4. MECHANICAL SYSTEMS - MULTIFAMILY: Combustion | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Combustion MECHANICAL SYSTEMS - MULTIFAMILY: Combustion 4_combustion.zip (14.52 MB) More Documents & Publications MECHANICAL SYSTEMS - MULTIFAMILY: Venting MECHANICAL SYSTEMS - MULTIFAMILY: Building as a System

  5. Mechanical Solutions Inc | Open Energy Information

    OpenEI (Open Energy Information) [EERE & EIA]

    Mechanical Solutions Inc Jump to: navigation, search Name: Mechanical Solutions Inc Place: New York Product: New York-based contractor. References: Mechanical Solutions Inc1 This...

  6. A class of ejecta transport test problems

    SciTech Connect

    Hammerberg, James E; Buttler, William T; Oro, David M; Rousculp, Christopher L; Morris, Christopher; Mariam, Fesseha G

    2011-01-31

    Hydro code implementations of ejecta dynamics at shocked interfaces presume a source distribution function ofparticulate masses and velocities, f{sub 0}(m, v;t). Some of the properties of this source distribution function have been determined from extensive Taylor and supported wave experiments on shock loaded Sn interfaces of varying surface and subsurface morphology. Such experiments measure the mass moment of f{sub o} under vacuum conditions assuming weak particle-particle interaction and, usually, fully inelastic capture by piezo-electric diagnostic probes. Recently, planar Sn experiments in He, Ar, and Kr gas atmospheres have been carried out to provide transport data both for machined surfaces and for coated surfaces. A hydro code model of ejecta transport usually specifies a criterion for the instantaneous temporal appearance of ejecta with source distribution f{sub 0}(m, v;t{sub 0}). Under the further assumption of separability, f{sub 0}(m,v;t{sub 0}) = f{sub 1}(m)f{sub 2}(v), the motion of particles under the influence of gas dynamic forces is calculated. For the situation of non-interacting particulates, interacting with a gas via drag forces, with the assumption of separability and simplified approximations to the Reynolds number dependence of the drag coefficient, the dynamical equation for the time evolution of the distribution function, f(r,v,m;t), can be resolved as a one-dimensional integral which can be compared to a direct hydro simulation as a test problem. Such solutions can also be used for preliminary analysis of experimental data. We report solutions for several shape dependent drag coefficients and analyze the results of recent planar dsh experiments in Ar and Xe.

  7. RAPID/Roadmap/20-FD-a | Open Energy Information

    OpenEI (Open Energy Information) [EERE & EIA]

    Narrative 20-FD-a.1 - Does the well require immediate action? If the well has experienced reservoir, drilling or mechanical integrity problems that can not be repaired, it may be...

  8. Phase space quantum mechanics - Direct

    SciTech Connect

    Nasiri, S.; Sobouti, Y.; Taati, F.

    2006-09-15

    Conventional approach to quantum mechanics in phase space (q,p), is to take the operator based quantum mechanics of Schroedinger, or an equivalent, and assign a c-number function in phase space to it. We propose to begin with a higher level of abstraction, in which the independence and the symmetric role of q and p is maintained throughout, and at once arrive at phase space state functions. Upon reduction to the q- or p-space the proposed formalism gives the conventional quantum mechanics, however, with a definite rule for ordering of factors of noncommuting observables. Further conceptual and practical merits of the formalism are demonstrated throughout the text.

  9. Small fatigue cracks: mechanics, mechanisms and engineering applications

    SciTech Connect

    Ritchie, R.O.; Peters, J.O.

    2001-05-01

    Damage-tolerant design and life-prediction methodologies have been practiced for metallic structures for decades, although their application to brittle materials, such as ceramics, and intermetallic alloys, still poses particular problems, primarily because of their extreme flaw-sensitivity.

  10. Thermoelectric Mechanical Reliability | Department of Energy

    Energy.gov [DOE] (indexed site)

    Transport Properties, Thermal Response, and Mechanical Reliability of Thermoelectric Materials and Devices for Automotive Waste Heat Recovery Thermoelectric Mechanical Reliability

  11. The application of Flowmonta for environmental problems

    SciTech Connect

    Sass, I.; Caldonazzi, O.; Beyer, T. de

    1997-12-31

    The combination of Horizontal Directional Drilling techniques with High Pressure Injection techniques led to the development of Horizontal Directional Injected Barriers under ground. Specially developed injection fluid mixture of Montan wax, cement and bentonite is the basis for the Flowmonta process. The first field test was made in a mining`s landfill in 1993. It confirmed the basic procedure. In a two-stepped, large-scale test in 1995, different injection techniques and injection fluids were tested. Intensive investigations in the field and in the laboratory were made. The Flowmonta-barrier then was excavated to enabled the direct observation and evaluation of the extent of the injections. During the first phase of the test several mixtures and injection techniques were tested. In the second phase a complete three dimensional sealing basin was created. The permeability of this sealing basin was tested in-situ. After excavation, hydraulic and mechanical surveys were made in the laboratory. By using the one-phase jet grouting technique, a penetrative depth of 12 meters on each side of the drilling was reached. A test using the Duplex technique resulted in a penetration of up to 2 meters and more on each side of the center bore. The permeability of the injection area was lowered by two exponential orders compared to the surrounding soil. SEM-images showed the structure of the injected material, as well as Montan wax spheres to have of 0,2 {mu}m to 2 {mu}m in diameter. X-ray diffraction, annealing and toluene-extraction gave a semiquantitative proportion analysis. Montan wax disproportion effects were observed in the barrier. Recently geophysical investigation methods still give no satisfying data.

  12. Vessel V-7 and V-8 repair and characterization of insert material. Final report

    SciTech Connect

    Domian, H.A.

    1984-05-01

    Pieces of Type SA508-2 steel, specially tempered to produce a high-impact-transition temperature, were welded in the side walls of Intermediate Test Vessels V-7 and V-8. These vessels are to be tested by the Oak Ridge National Laboratory (ORNL) in the Pressurized-Thermal-Shock (PTS) Project of the Heavy-Section Steel Technology (HSST) Program. A comparable piece of forging taken from the same source and heat treated with the vessels was characterized for its mechanical properties to provide data for use in the PTS tests.

  13. Repair of a Mirror Coating on a Large Optic for High Laser Damage Applications using Ion Milling and Over-Coating Methods.

    DOE PAGES [OSTI]

    Field, Ella Suzanne; Bellum, John Curtis; Kletecka, Damon E.

    2016-06-01

    When an optical coating is damaged, deposited incorrectly, or is otherwise unsuitable, the conventional method to restore the optic often entails repolishing the optic surface, which can incur a large cost and long lead time. We propose three alternative options to repolishing, including (i) burying the unsuitable coating under another optical coating, (ii) using ion milling to etch the unsuitable coating completely from the optic surface, and then recoating the optic, and (iii) using ion milling to etch through a number of unsuitable layers, leaving the rest of the coating intact, and then recoating the layers that were etched. Repairsmore » were made on test optics with dielectric mirror coatings according to the above three options. The mirror coatings to be repaired were quarter wave stacks of HfO2 and SiO2 layers for high reflection at 1054 nm at 45° incidence in P-polarization. One of the coating layers was purposely deposited incorrectly as Hf metal instead of HfO2 to evaluate the ability of each repair method to restore the coating’s high laser-induced damage threshold (LIDT) of 64.0 J/cm2. Finally, the repaired coating with the highest resistance to laser-induced damage was achieved using repair method (ii) with an LIDT of 49.0 – 61.0 J/cm2.« less

  14. Prediction of residual stress field in mechanically expanded 0.750 inch diameter steam generator tube plugs. Part 1: 2-D solution

    SciTech Connect

    Williams, D.K.

    1996-12-01

    One of the most formidable classes of problems that arises in the commercial nuclear power industry is the determination of the residual stress field in steam generator tubes. As early as 1983, it was reported that primary water stress corrosion cracking (PWSCC) of Alloy 600 steam generator tubes had occurred at a low frequency. The degradation of steam generator tubing by PWSCC has resulted in unplanned nuclear plant outages and costly repair operations such as tube plugging and eventually steam generator replacement. Although the previous discussion centered around the PWSCC of the Inconel 600 tubes, the repair plugs which are intended to isolate the damaged tubes from the primary system, have also begun to show similar types of cracking in the rolled transitions. Plug severance is highly undesirable in the nuclear plant because the primary-to-secondary barrier would then be voided and radioactive fluid would escape to the non-radioactive feedwater system. At the present time, although the tube problems have been discussed extensively in the literature roll plugs and their associated SCC have yet to be fully addressed. In addition, roll plus present a different set of loads, expansion regions, discontinuities, and displacement boundary conditions to be analyzed. The method of solution to the subject roll expansion problem employs the use of a general purpose finite element program to mathematically simulate the expansion process. The hydraulic expansion simulation is accomplished by matching the final displacements of an installed plug for which field measurements are available. Because of the symmetry which exists in the geometry and loading, this problem is modeled and analyzed as an axisymmetric problem. The resulting stress field throughout the plug, and in particular, in the rolled transition region, is calculated.

  15. Mechanically balanced tapered plug valve

    DOEpatents

    Anaya, Jose R.

    1985-01-01

    The invention is a novel hermetic tapered plug valve having a spring-like resilient mechanism for providing axial balance to the plug and thereby prevent valve lock up.

  16. Mechanical Behavior of Indium Nanostructures

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Publication about this research: G. Lee, J.Y. Kim, A.S. Budiman, N. Tamura, M. Kunz, K. Chen, M.J. Burek, J.R. Greer, and T.Y. Tsui, "Fabrication, structure and mechanical...

  17. Parallel Simulation of Three-Dimensional Free Surface Fluid Flow Problems

    SciTech Connect

    BAER,THOMAS A.; SACKINGER,PHILIP A.; SUBIA,SAMUEL R.

    1999-10-14

    Simulation of viscous three-dimensional fluid flow typically involves a large number of unknowns. When free surfaces are included, the number of unknowns increases dramatically. Consequently, this class of problem is an obvious application of parallel high performance computing. We describe parallel computation of viscous, incompressible, free surface, Newtonian fluid flow problems that include dynamic contact fines. The Galerkin finite element method was used to discretize the fully-coupled governing conservation equations and a ''pseudo-solid'' mesh mapping approach was used to determine the shape of the free surface. In this approach, the finite element mesh is allowed to deform to satisfy quasi-static solid mechanics equations subject to geometric or kinematic constraints on the boundaries. As a result, nodal displacements must be included in the set of unknowns. Other issues discussed are the proper constraints appearing along the dynamic contact line in three dimensions. Issues affecting efficient parallel simulations include problem decomposition to equally distribute computational work among a SPMD computer and determination of robust, scalable preconditioners for the distributed matrix systems that must be solved. Solution continuation strategies important for serial simulations have an enhanced relevance in a parallel coquting environment due to the difficulty of solving large scale systems. Parallel computations will be demonstrated on an example taken from the coating flow industry: flow in the vicinity of a slot coater edge. This is a three dimensional free surface problem possessing a contact line that advances at the web speed in one region but transitions to static behavior in another region. As such, a significant fraction of the computational time is devoted to processing boundary data. Discussion focuses on parallel speed ups for fixed problem size, a class of problems of immediate practical importance.

  18. Mitigating strategies for CO/sub 2/ problems

    SciTech Connect

    Lave, L B

    1980-08-01

    Vast uncertainties surround the ability to predict the social effects of increased carbon dioxide concentrations in the atmosphere during the next century; fossil fuel combustion rates will change, predicting global climate changes is difficult, and predicting the resulting social reactions to these change is essentially impossible. Unfortunately, the effects of carbon dioxide are likely to be insidious and difficult to connect to climate change. Myriad effects, both good and bad are unlikely to be recognized as caused by carbon dioxide. Conscious adaptation policies have the government or other social institutions act directly to mandate change in behavior through laws, fines, or subsidies. Unfortunately, such actions cannot be tailored to achieve precise objectives; they are blunt tools that should be used only for important goals and then sparingly. Unconscious adaptation takes place through behavioral changes induced by the market place or social institutions. These mechanisms can be swift and powerful, but are difficult to manipulate. Actions such as monitoring climate change and taking care to inform important groups of the current state of knowledge on carbon dioxide induced climate changes can help to speed adaptation along with contingency planning and development of nonfossil fuel technologies can speed adaptation. More important are plans which would set unconscious adaptation into motion, such as plans to disseminate information on the problem and behavior which will help individuals or firms. Of greatest importance is having a society that can quickly perceive and adapt to the new regime. This means a strong economy, high scientific and engineering capabilities, a well educated population, and a more flexible, resilient capital stock. Carbon dioxide can serve as a catalyst in promoting policies that are justified for a host of reasons.

  19. Mechanical drive for blood pump

    DOEpatents

    Bifano, N.J.; Pouchot, W.D.

    1975-07-29

    This patent relates to a highly efficient blood pump to be used as a replacement for a ventricle of the human heart to restore people disabled by heart disease. The mechanical drive of the present invention is designed to operate in conjunction with a thermoelectric converter power source. The mechanical drive system essentially converts the output of a rotary power into pulsatile motion so that the power demand from the thermoelectric converter remains essentially constant while the blood pump output is pulsed. (auth)

  20. A fast grain-growth mechanism revealed in nanocrystalline ceramic-oxides

    SciTech Connect

    Aidhy, Dilpuneet S; Zhang, Yanwen; Weber, William J

    2014-01-01

    Grain growth problem in nanocrystalline ceramic-oxides renders their highly attractive properties practically unusable due to limited understanding on the underlying grain growth mechanisms. Two conventional 'slow' grain-growth mechanisms, i.e., curvature-driven and grainrotation driven, are shown to be thermally active, and the discovery of a 'fast' disorder-driven mechanism is revealed using molecular dynamics simulation on nanocrystalline ceria, in conjunction with experimental observations. We elucidate that this disorder mechanism drives the unexpected fast grain growth observed experimentally during synthesis and irradiation conditions.

  1. Mechanical Response of Thermoelectric Materials

    SciTech Connect

    Wereszczak, Andrew A.; Case, Eldon D.

    2015-05-01

    A sufficient mechanical response of thermoelectric materials (TEMats) to structural loadings is a prerequisite to the exploitation of any candidate TEMat's thermoelectric efficiency. If a TEMat is mechanically damaged or cracks from service-induced stresses, then its thermal and electrical functions can be compromised or even cease. Semiconductor TEMats tend to be quite brittle and have a high coefficient of thermal expansion; therefore, they can be quite susceptible to mechanical failure when subjected to operational thermal gradients. Because of this, sufficient mechanical response (vis-a-vis, mechanical properties) of any candidate TEMat must be achieved and sustained in the context of the service-induced stress state to which it is subjected. This report provides an overview of the mechanical responses of state-of-the-art TEMats; discusses the relevant properties that are associated with those responses and their measurement; and describes important, nonequilibrium phenomena that further complicate their use in thermoelectric devices. For reference purposes, the report also includes several appendixes that list published data on elastic properties and strengths of a variety of TEMats.

  2. Modulation of DNA repair capacity and mRNA expression levels of XRCC1, hOGG1 and XPC genes in styrene-exposed workers

    SciTech Connect

    Hanova, Monika; Stetina, Rudolf; Vodickova, Ludmila; Vaclavikova, Radka; Hlavac, Pavel; Smerhovsky, Zdenek; Naccarati, Alessio; Polakova, Veronika; Soucek, Pavel; Kuricova, Miroslava; Manini, Paola; Kumar, Rajiv; Hemminki, Kari; Vodicka, Pavel

    2010-11-01

    Decreased levels of single-strand breaks in DNA (SSBs), reflecting DNA damage, have previously been observed with increased styrene exposure in contrast to a dose-dependent increase in the base-excision repair capacity. To clarify further the above aspects, we have investigated the associations between SSBs, micronuclei, DNA repair capacity and mRNA expression in XRCC1, hOGG1 and XPC genes on 71 styrene-exposed and 51 control individuals. Styrene concentrations at workplace and in blood characterized occupational exposure. The workers were divided into low (below 50 mg/m{sup 3}) and high (above 50 mg/m{sup 3}) styrene exposure groups. DNA damage and DNA repair capacity were analyzed in peripheral blood lymphocytes by Comet assay. The mRNA expression levels were determined by qPCR. A significant negative correlation was observed between SSBs and styrene concentration at workplace (R = - 0.38, p = 0.001); SSBs were also significantly higher in men (p = 0.001). The capacity to repair irradiation-induced DNA damage was the highest in the low exposure group (1.34 {+-} 1.00 SSB/10{sup 9} Da), followed by high exposure group (0.72 {+-} 0.81 SSB/10{sup 9} Da) and controls (0.65 {+-} 0.82 SSB/10{sup 9} Da). The mRNA expression levels of XRCC1, hOGG1 and XPC negatively correlated with styrene concentrations in blood and at workplace (p < 0.001) and positively with SSBs (p < 0.001). Micronuclei were not affected by styrene exposure, but were higher in older persons and in women (p < 0.001). In this study, we did not confirm previous findings on an increased DNA repair response to styrene-induced genotoxicity. However, negative correlations of SSBs and mRNA expression levels of XRCC1, hOGG1 and XPC with styrene exposure warrant further highly-targeted study.

  3. Mechanics

    Energy.gov [DOE]

    In BriefPlayers must connect buildings together by allocating resources in a resource chain across the map. They must reach and resolve their Objective within a given number of turns to succeed.To...

  4. Computing confidence intervals on solution costs for stochastic grid generation expansion problems.

    SciTech Connect

    Woodruff, David L..; Watson, Jean-Paul

    2010-12-01

    A range of core operations and planning problems for the national electrical grid are naturally formulated and solved as stochastic programming problems, which minimize expected costs subject to a range of uncertain outcomes relating to, for example, uncertain demands or generator output. A critical decision issue relating to such stochastic programs is: How many scenarios are required to ensure a specific error bound on the solution cost? Scenarios are the key mechanism used to sample from the uncertainty space, and the number of scenarios drives computational difficultly. We explore this question in the context of a long-term grid generation expansion problem, using a bounding procedure introduced by Mak, Morton, and Wood. We discuss experimental results using problem formulations independently minimizing expected cost and down-side risk. Our results indicate that we can use a surprisingly small number of scenarios to yield tight error bounds in the case of expected cost minimization, which has key practical implications. In contrast, error bounds in the case of risk minimization are significantly larger, suggesting more research is required in this area in order to achieve rigorous solutions for decision makers.

  5. Environmental assistance as national security policy: Helping the former Soviet Union find solutions to its environmental problems

    SciTech Connect

    Dunaway, R.L.

    1995-11-01

    Since the fall of Communism in the former Soviet Union, US Presidents and policy makers have stressed the importance of helping Russia and the Newly Independent States develop democratic forms of government and forge strong economic and environmental ties with other nations throughout the world. The US can and should play a role in helping the Commonwealth of Independent States repair decades of damage caused by Cold War-driven industrial and nuclear development. This report describes some of the region`s most serious environmental problems and their potential to spread throughout the affected areas to neighboring countries. It provides an overview of the emerging environmental component of the US. National Security Strategy first proposed by President Bush. Finally, it describes an ambitious proposal to implement geographic information system (GIS) technology as a means of helping the former Soviet Union identify and monitor existing and potential environmental hazards. The ability to locate, analyze, and track existing damage reliably, as a prelude to predicting potential threats, is a necessary first step in developing a viable strategy to protect environmental, economic, and social resources, both in the former Soviet Union and world-wide.

  6. Numerical solution of control problems governed by nonlinear differential equations

    SciTech Connect

    Heinkenschloss, M.

    1994-12-31

    In this presentation the author investigates an iterative method for the solution of optimal control problems. These problems are formulated as constrained optimization problems with constraints arising from the state equation and in the form of bound constraints on the control. The method for the solution of these problems uses the special structure of the problem arising from the bound constraint and the state equation. It is derived from SQP methods and projected Newton methods and combines the advantages of both methods. The bound constraint is satisfied by all iterates using a projection, the nonlinear state equation is satisfied in the limit. Only a linearized state equation has to be solved in every iteration. The solution of the linearized problems are done using multilevel methods and GMRES.

  7. On the computational complexity of sequence design problems

    SciTech Connect

    Hart, W.E. [Sandia National Labs., Albuquerque, NM (United States)

    1997-12-01

    Inverse protein folding concerns the identification of an amino acid sequence that folds to a given structure. Sequence design problems attempt to avoid the apparant difficulty of inverse protein folding by defining an energy that can be minimized to find protein-like sequences. We evaluate the practical relevance of two sequence design problems by analyzing their computational complexity. We show that the canonical method of sequence design is intractable and describe approximation algorithms for this problem. We also describe an efficient algorithm that exactly solves the grand canonical method. Our analysis shows how sequence design problems can fail to reduce the difficulty of the inverse protein folding problem and highlights the need to analyze these problems to evaluate their practical relevance. 10 refs., 8 figs.

  8. On the computational complexity of sequence design problems

    SciTech Connect

    Hart, W.E. [Sandia National Labs., Albuquerque, NM (United States). Algorithms and Discrete Mathematics Dept.

    1996-12-31

    Inverse protein folding concerns the identification of an amino acid sequence that folds to a given structure. Sequence design problems attempt to avoid the apparent difficulty of inverse protein folding by defining an energy that can be minimized to find protein-like sequences. The authors evaluate the practical relevance of two sequence design problems by analyzing their computation complexity. They show that the canonical method of sequence design is intractable, and describe approximation algorithms for this problem. The authors also describe an efficient algorithm that exactly solves the grand canonical method. The analysis shows how sequence design problems can fail to reduce the difficulty of the inverse protein folding problem, and highlights the need to analyze these problems to evaluate their practical relevance.

  9. Crowdsourcing Initiative Seeks Buildings-Related Problems to Solve |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Crowdsourcing Initiative Seeks Buildings-Related Problems to Solve Crowdsourcing Initiative Seeks Buildings-Related Problems to Solve June 30, 2015 - 9:00am Addthis Calling all building technology innovators! The Building Technologies Office is partnering with the successful SunShot Catalyst crowdsourcing initiative to identify and solve problems related to software development, data, and/or automation. In the first, "Ideation" phase of the initiative, those

  10. On parameterization of the inverse problem for estimating aquifer...

    Office of Scientific and Technical Information (OSTI)

    Title: On parameterization of the inverse problem for estimating aquifer properties using tracer data Authors: Kowalsky, M. B. ; Finsterle, S. ; Commer, M. ; Williams, K. H. ; ...

  11. Crowdsourcing Initiative Seeks Buildings-Related Problems to...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    The Building Technologies Office is partnering with the successful SunShot Catalyst crowdsourcing initiative to identify and solve problems related to software development, data, ...

  12. History, Applications, Numerical Values and Problems with the...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Numerical Values and Problems with the Calculation of EROI (Energy Return on Energy Investment) Professor Charles Hall State University of NY College of Environmental Science and...

  13. European Geothermal Drilling Experience-Problem Areas and Case...

    Office of Scientific and Technical Information (OSTI)

    Drilling Experience-Problem Areas and Case Studies Baron, G.; Ungemach, P. 15 GEOTHERMAL ENERGY; BOREHOLES; DRILLING; EVALUATION; EXPLORATION; GEOTHERMAL RESOURCES; ITALY;...

  14. Verification Method for SSI Problems with Extended Parameter Ranges

    Office of Energy Efficiency and Renewable Energy (EERE)

    Verification Method for SSI Problems with Extended Parameter Ranges 2014 U.S. DOE Natural Phenomena Hazards Meeting Carl J. Costantino and Associates www.cjcassoc.com

  15. FELIX: advances in modeling forward and inverse icesheet problems...

    Office of Scientific and Technical Information (OSTI)

    icesheet problems. Authors: Perego, Mauro ; Eldred, Michael S. ; Gunazburger, Max ; Salinger, Andrew G. ; Kalashnikova, Irina ; Ju, L. ; Hoffman, M. ; Leng, W. ; Price, S ;...

  16. Trending and root cause analysis of TWRS radiological problem reports

    SciTech Connect

    Brown, R.L.

    1997-07-31

    This document provides a uniform method for trending and performing root cause analysis for radiological problem reports at Tank Waste Remediation System (TWRS).

  17. Synthetic fossil fuel technologies: health problems and intersociety...

    Office of Scientific and Technical Information (OSTI)

    Conference: Synthetic fossil fuel technologies: health problems and intersociety cooperation Citation Details In-Document Search Title: Synthetic fossil fuel technologies: health ...

  18. Using Energy-Filtered TEM to Solve Practical Materials Problems...

    Office of Scientific and Technical Information (OSTI)

    Title: Using Energy-Filtered TEM to Solve Practical Materials Problems With Inspirations from Gareth Thomas. Abstract not provided. Authors: Sugar, Joshua Daniel ; El Gabaly ...

  19. Ethylene-Vinyl Acetate Potential Problems for Photovoltaic Packaging...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Ethylene-Vinyl Acetate Potential Problems for Photovoltaic Packaging Preprint M.D. Kempe, ... the 2006 IEEE 4 th World Conference on Photovoltaic Energy Conversion (WCPEC-4) Waikoloa, ...

  20. Majorana Electroformed Copper Mechanical Analysis

    SciTech Connect

    Overman, Nicole R.; Overman, Cory T.; Kafentzis, Tyler A.; Edwards, Danny J.; Hoppe, Eric W.

    2012-04-30

    The MAJORANA DEMONSTRATOR is a large array of ultra-low background high-purity germanium detectors, enriched in 76Ge, designed to search for zero-neutrino double-beta decay. The DEMONSTRATOR will utilize ultra high purity electroformed copper for a variety of detector components and shielding. A preliminary mechanical evaluation was performed on the Majorana prototype electroformed copper material. Several samples were removed from a variety of positions on the mandrel. Tensile testing, optical metallography, scanning electron microscopy, and hardness testing were conducted to evaluate mechanical response. Analyses carried out on the Majorana prototype copper to this point show consistent mechanical response from a variety of test locations. Evaluation shows the copper meets or exceeds the design specifications.

  1. MULTIPLE DIFFERENTIAL ROTARY MECHANICAL DRIVE

    DOEpatents

    Smits, R.G.

    1964-01-28

    This patent relates to a mechanism suitable for such applications as driving two spaced-apart spools which carry a roll film strip under conditions where the film movement must be rapidly started, stopped, and reversed while maintaining a constant tension on the film. The basic drive is provided by a variable speed, reversible rnotor coupled to both spools through a first differential mechanism and driving both spools in the same direction. A second motor, providing a constant torque, is connected to the two spools through a second differential mechanism and is coupled to impart torque to one spool in a first direction anid to the other spool in the reverse direction thus applying a constant tension to the film passing over the two spools irrespective of the speed or direction of rotation thereof. (AEC)

  2. Negative hydrogen ion production mechanisms

    SciTech Connect

    Bacal, M.; Wada, M.

    2015-06-15

    Negative hydrogen/deuterium ions can be formed by processes occurring in the plasma volume and on surfaces facing the plasma. The principal mechanisms leading to the formation of these negative ions are dissociative electron attachment to ro-vibrationally excited hydrogen/deuterium molecules when the reaction takes place in the plasma volume, and the direct electron transfer from the low work function metal surface to the hydrogen/deuterium atoms when formation occurs on the surface. The existing theoretical models and reported experimental results on these two mechanisms are summarized. Performance of the negative hydrogen/deuterium ion sources that emerged from studies of these mechanisms is reviewed. Contemporary negative ion sources do not have negative ion production electrodes of original surface type sources but are operated with caesium with their structures nearly identical to volume production type sources. Reasons for enhanced negative ion current due to caesium addition to these sources are discussed.

  3. ION PRODUCING MECHANISM (CHARGE CUPS)

    DOEpatents

    Brobeck, W.W.

    1959-04-21

    The problems of confining a charge material in a calutron and uniformly distributing heat to the charge is described. The charge is held in a cup of thermally conductive material removably disposed within the charge chamber of the ion source block. A central thermally conducting stem is incorporated within the cup for conducting heat to the central portion of the charge contained within the cup.

  4. Scalable computations in penetration mechanics

    SciTech Connect

    Kimsey, K.D.; Schraml, S.J.; Hertel, E.S.

    1998-01-01

    This paper presents an overview of an explicit message passing paradigm for an Eulerian finite volume method for modeling solid dynamics problems involving shock wave propagation, multiple materials, and large deformations. Three-dimensional simulations of high-velocity impact were conducted on the IBM SP2, the SGI Power challenge Array, and the SGI Origin 2000. The scalability of the message-passing code on distributed-memory and symmetric multiprocessor architectures is presented and compared to the ideal linear performance.

  5. Higher-order transformation and the distributed data problem.

    SciTech Connect

    Winter, Victor Lono; Subramaniam, Mahadevan

    2003-12-01

    The distributed data problem, is characterized by the desire to bring together semantically related data from syntactically unrelated portions of a term. Two strategic combinators, dynamic and transient, are introduced in the context of a classical strategic programming framework. The impact of the resulting system on instances of the distributed data problem is then explored.

  6. On a Highly Nonlinear Self-Obstacle Optimal Control Problem

    SciTech Connect

    Di Donato, Daniela; Mugnai, Dimitri

    2015-10-15

    We consider a non-quadratic optimal control problem associated to a nonlinear elliptic variational inequality, where the obstacle is the control itself. We show that, fixed a desired profile, there exists an optimal solution which is not far from it. Detailed characterizations of the optimal solution are given, also in terms of approximating problems.

  7. LANSCE wire scanning diagnostics device mechanical design

    SciTech Connect

    Rodriguez Esparza, Sergio

    2010-01-01

    The Los Alamos Neutron Science Center (LANSCE) is one of the major experimental science facilities at the Los Alamos National Laboratory (LANL). The core of LANSCE's work lies in the operation of a powerful linear accelerator, which accelerates protons up to 84% the speed oflight. These protons are used for a variety of purposes, including materials testing, weapons research and isotopes production. To assist in guiding the proton beam, a series of over one hundred wire scanners are used to measure the beam profile at various locations along the half-mile length of the particle accelerator. A wire scanner is an electro-mechanical device that moves a set of wires through a particle beam and measures the secondary emissions from the resulting beam-wire interaction to obtain beam intensity information. When supplemented with data from a position sensor, this information is used to determine the cross-sectional profile of the beam. This measurement allows beam operators to adjust parameters such as acceleration, beam steering, and focus to ensure that the beam reaches its destination as effectively as possible. Some of the current wire scanners are nearly forty years old and are becoming obsolete. The problem with current wire scanners comes in the difficulty of maintenance and reliability. The designs of these wire scanners vary making it difficult to keep spare parts that would work on all designs. Also many of the components are custom built or out-dated technology and are no longer in production.

  8. Multiple mechanisms of PCB neurotoxicity

    SciTech Connect

    Carpenter, D.O.; Stoner, C.T.; Lawrence, D.A.

    1996-12-31

    Polychlorinated biphenyls (PCBs) have been implicated in cancer, but many of the symptoms in humans exposed to PCBs are related to the nervous system and behavior. We demonstrated three different direct mechanisms whereby PCBs are neurotoxic in rats. By using flow cytometry, we demonstrated that the orthosubstituted PCB congener 2,4,4{prime}, but neither TCDD nor the coplanar PCB congener 3,4,5,3{prime},4{prime}, causes rapid death of cerebellar granule cells. The ortho-substituted congener 2,4,4{prime} reduced long-term potentiation, an indicator of cognitive potential, in hippocampal brain slices, but a similar effect was observed for the coplanar congener 3,4,3{prime},4{prime}, indicating that this effect may be caused by both ortho- and coplanar congeners by mechanisms presumably not mediated via the Ah receptor. It was previously shown that some ortho-substituted PCB congeners cause a reduction in levels of the neurotransmitter dopamine, and we present in vitro and in vivo evidence that this is due to reduction of synthesis of dopamine via inhibition of the enzyme tyrosine hydroxylase. Thus, PCBs have a variety of mechanisms of primary neurotoxicity, and neurotoxicity is a characteristic of ortho-substituted, non-dioxin-like congeners as well as some coplanar congeners. The relative contribution of each of these mechanisms to the loss of cognitive function in humans exposed to PCBs remains to be determined. 42 refs., 3 figs., 1 tab.

  9. Battery Vent Mechanism And Method

    SciTech Connect

    Ching, Larry K. W.

    2000-02-15

    Disclosed herein is a venting mechanism for a battery. The venting mechanism includes a battery vent structure which is located on the battery cover and may be integrally formed therewith. The venting mechanism includes an opening extending through the battery cover such that the opening communicates with a plurality of battery cells located within the battery case. The venting mechanism also includes a vent manifold which attaches to the battery vent structure. The vent manifold includes a first opening which communicates with the battery vent structure opening and second and third openings which allow the vent manifold to be connected to two separate conduits. In this manner, a plurality of batteries may be interconnected for venting purposes, thus eliminating the need to provide separate vent lines for each battery. The vent manifold may be attached to the battery vent structure by a spin-welding technique. To facilitate this technique, the vent manifold may be provided with a flange portion which fits into a corresponding groove portion on the battery vent structure. The vent manifold includes an internal chamber which is large enough to completely house a conventional battery flame arrester and overpressure safety valve. In this manner, the vent manifold, when installed, lessens the likelihood of tampering with the flame arrester and safety valve.

  10. Mechanical scriber for semiconductor devices

    DOEpatents

    Lin, P.T.

    1985-03-05

    A mechanical scriber using a scribing tip, such as a diamond, provides controlled scriber forces with a spring-loaded compound lever arrangement. The scribing force and range of scribing depth are adjusted by a pair of adjustable micrometer heads. A semiconductor device, such as a multilayer solar cell, can be formed into scribed strips at each layer. 5 figs.

  11. Mechanical scriber for semiconductor devices

    DOEpatents

    Lin, Peter T.

    1985-01-01

    A mechanical scriber using a scribing tip, such as a diamond, provides controlled scriber forces with a spring-loaded compound lever arrangement. The scribing force and range of scribing depth are adjusted by a pair of adjustable micrometer heads. A semiconductor device, such as a multilayer solar cell, can be formed into scribed strips at each layer.

  12. Domain wall and isocurvature perturbation problems in axion models

    SciTech Connect

    Kawasaki, Masahiro; Yoshino, Kazuyoshi; Yanagida, Tsutomu T. E-mail: tsutomu.tyanagida@ipmu.jp

    2013-11-01

    Axion models have two serious cosmological problems, domain wall and isocurvature perturbation problems. In order to solve these problems we investigate the Linde's model in which the field value of the Peccei-Quinn (PQ) scalar is large during inflation. In this model the fluctuations of the PQ field grow after inflation through the parametric resonance and stable axionic strings may be produced, which results in the domain wall problem. We study formation of axionic strings using lattice simulations. It is found that in chaotic inflation the axion model is free from both the domain wall and the isocurvature perturbation problems if the initial misalignment angle ?{sub a} is smaller than O(10{sup ?2}). Furthermore, axions can also account for the dark matter for the breaking scale v ? 10{sup 12?16}GeV and the Hubble parameter during inflation H{sub inf}?<10{sup 11?12}GeV in general inflation models.

  13. Russian Doll Search for solving Constraint Optimization problems

    SciTech Connect

    Verfaillie, G.; Lemaitre, M.

    1996-12-31

    If the Constraint Satisfaction framework has been extended to deal with Constraint Optimization problems, it appears that optimization is far more complex than satisfaction. One of the causes of the inefficiency of complete tree search methods, like Depth First Branch and Bound, lies in the poor quality of the lower bound on the global valuation of a partial assignment, even when using Forward Checking techniques. In this paper, we introduce the Russian Doll Search algorithm which replaces one search by n successive searches on nested subproblems (n being the number of problem variables), records the results of each search and uses them later, when solving larger subproblems, in order to improve the lower bound on the global valuation of any partial assignment. On small random problems and on large real scheduling problems, this algorithm yields surprisingly good results, which greatly improve as the problems get more constrained and the bandwidth of the used variable ordering diminishes.

  14. Workshops and problems for benchmarking eddy current codes

    SciTech Connect

    Turner, L.R.; Davey, K.; Ida, N.; Rodger, D.; Kameari, A.; Bossavit, A.; Emson, C.R.I.

    1988-08-01

    A series of six workshops was held in 1986 and 1987 to compare eddy current codes, using six benchmark problems. The problems included transient and steady-state ac magnetic fields, close and far boundary conditions, magnetic and non-magnetic materials. All the problems were based either on experiments or on geometries that can be solved analytically. The workshops and solutions to the problems are described. Results show that many different methods and formulations give satisfactory solutions, and that in many cases reduced dimensionality or coarse discretization can give acceptable results while reducing the computer time required. A second two-year series of TEAM (Testing Electromagnetic Analysis Methods) workshops, using six more problems, is underway. 12 refs., 15 figs., 4 tabs.

  15. Shell Element Verification & Regression Problems for DYNA3D

    SciTech Connect

    Zywicz, E

    2008-02-01

    A series of quasi-static regression/verification problems were developed for the triangular and quadrilateral shell element formulations contained in Lawrence Livermore National Laboratory's explicit finite element program DYNA3D. Each regression problem imposes both displacement- and force-type boundary conditions to probe the five independent nodal degrees of freedom employed in the targeted formulation. When applicable, the finite element results are compared with small-strain linear-elastic closed-form reference solutions to verify select aspects of the formulations implementation. Although all problems in the suite depict the same geometry, material behavior, and loading conditions, each problem represents a unique combination of shell formulation, stabilization method, and integration rule. Collectively, the thirty-six new regression problems in the test suite cover nine different shell formulations, three hourglass stabilization methods, and three families of through-thickness integration rules.

  16. Mechanical effects in cookoff modeling

    SciTech Connect

    Gross, R.J.; Baer, M.R.; Hobbs, M.L.

    1994-07-01

    Complete cookoff modeling of energetic material in confined geometries must couple thermal, chemical and mechanical effects. In the past, modeling has focused on the prediction of the onset of combustion behavior based only on thermal-chemistry effects with little or no regard to the mechanical behavior of the energetic material. In this paper, an analysis tool is outlined which couples thermal, chemical, and mechanical behavior for one-dimensional Geometries comprised of multi-materials. A reactive heat flow code, XCHEM, and a quasistatic mechanics code, SANTOS, have been completely coupled using, a reactive, elastic-plastic constitutive model describing pressurization of the energetic material. This new Thermally Reactive Elastic-plastic explosive code, TREX, was developed to assess the coupling, of mechanics with thermal chemistry making multidimensional cookoff analysis possible. In this study, TREX is applied to confined and unconfined systems. The confined systems simulate One-Dimensional Time to explosion (ODTX) experiments in both spherical and cylindrical configurations. The spherical ODTX system is a 1.27 cm diameter sphere of TATB confined by aluminum exposed to a constant external temperature. The cylindrical ODTX system is an aluminum tube filled with HMX, NC, and inert exposed to a constant temperature bath. Finally. an unconfined system consisting of a hollow steel cylinder filled with a propellant composed of Al, RMX, and NC, representative of a rocket motor, is considered. This model system is subjected to transient internal and external radiative/convective boundary conditions representative of 5 minutes exposure to a fire. The confined systems show significant pressure prior to ignition, and the unconfined system shows extrusion of the propellent suggesting that the energetic material becomes more shock sensitive.

  17. Universal mechanism of thermo-mechanical deformation in metallic glasses

    DOE PAGES [OSTI]

    Dmowski, W.; Tong, Y.; Iwashita, T.; Egami, Takeshi; Yokoyama, Y.

    2015-02-11

    Here we investigated the atomistic structure of metallic glasses subjected to thermo-mechanical creep deformation using high energy x-ray diffraction and molecular dynamics simulation. The experiments were performed in-situ, at high temperatures as a time dependent deformation in the elastic regime, and ex-situ on samples quenched under stress. We show that all the anisotropic structure functions of the samples undergone thermo-mechanical creep can be scaled into a single curve, regardless of the magnitude of anelastic strain, stress level and the sign of the stress, demonstrating universal behavior and pointing to unique atomistic unit of anelastic deformation. The structural changes due tomore » creep are strongly localized within the second nearest neighbors, involving only a small group of atoms.« less

  18. Career Map: Mechanical Engineer | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Mechanical Engineer Career Map: Mechanical Engineer A mechanical engineer works with a large yellow robotic arm. Mechanical Engineer Position Title Mechanical Engineer Alternate Title(s) Project Engineer, Quality Engineer, Research Engineer, Design Engineer, Sales Engineer Education & Training Level Advanced, Bachelor's degree required, prefer graduate degree Education & Training Level Description Mechanical engineers need a bachelor's degree. A graduate degree is typically needed for

  19. Shaoxing Jinggong Mechanical and Electrical Research Institute...

    OpenEI (Open Energy Information) [EERE & EIA]

    Shaoxing Jinggong Mechanical and Electrical Research Institute Company SJMERI Jump to: navigation, search Name: Shaoxing Jinggong Mechanical and Electrical Research Institute...

  20. Mechanical control of electroresistive switching (Journal Article...

    Office of Scientific and Technical Information (OSTI)

    SciTech Connect Search Results Journal Article: Mechanical control of electroresistive switching Citation Details In-Document Search Title: Mechanical control of electroresistive ...

  1. Degradation Mechanisms and Development of Protective Coatings...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Mechanisms and Development of Protective Coatings for TES and HTF Containment Materials Degradation Mechanisms and Development of Protective Coatings for TES and HTF Containment ...

  2. Excitation Energy Sorting Mechanisms in Fission (Conference)...

    Office of Scientific and Technical Information (OSTI)

    Excitation Energy Sorting Mechanisms in Fission Citation Details In-Document Search Title: Excitation Energy Sorting Mechanisms in Fission You are accessing a document from the ...

  3. NREL: Technology Transfer - Popular Mechanics: Scientists Break...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Popular Mechanics: Scientists Break This Virtual Power Grid to Save the Real One July 27, 2015 Popular Mechanics describes how NREL's Energy Systems Integration Facility (ESIF)...

  4. Version pressure feedback mechanisms for speculative versioning...

    Office of Scientific and Technical Information (OSTI)

    Version pressure feedback mechanisms for speculative versioning caches Citation Details In-Document Search Title: Version pressure feedback mechanisms for speculative versioning ...

  5. CONTROL OF MECHANICALLY ACTIVATED POLYMERSOME FUSION: FACTORS...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Journal Article: CONTROL OF MECHANICALLY ACTIVATED POLYMERSOME FUSION: FACTORS AFFECTING FUSION. Citation Details In-Document Search Title: CONTROL OF MECHANICALLY ACTIVATED...

  6. Thermoelectric Mechanical Reliability | Department of Energy

    Energy.gov [DOE] (indexed site)

    0wereszczak.pdf (1.52 MB) More Documents & Publications Thermoelectric Mechanical Reliability Thermoelectric Mechanical Reliability Thermoelectrics Theory and Structure

  7. Degradation Mechanisms of Urea Selective Catalytic Reduction...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Technology Degradation Mechanisms of Urea Selective Catalytic Reduction Technology Deactivation Mechanisms of Base MetalZeolite Urea Selective Catalytic Reduction Materials

  8. Mechanical properties and energy absorption characteristics of...

    Office of Scientific and Technical Information (OSTI)

    Mechanical properties and energy absorption characteristics of a polyurethane foam Citation Details In-Document Search Title: Mechanical properties and energy absorption ...

  9. Microstructural evolution and mechanical behavior of metastable...

    Office of Scientific and Technical Information (OSTI)

    and mechanical behavior of metastable -type Ti-30Nb-1Mo-4Sn alloy with low modulus and high strength Title: Microstructural evolution and mechanical behavior of metastable ...

  10. Mechanical R&D | The Ames Laboratory

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    assembles mechanical components. In our efforts we utilize Autodesk Inventor and ESPRIT CADCAM Software by DP Technology Corp., among others. Our Mechanical Design staff also...

  11. Collapse Mechanisms Of Masonry Structures

    SciTech Connect

    Zuccaro, G.; Rauci, M.

    2008-07-08

    The paper outlines a possible approach to typology recognition, safety check analyses and/or damage measuring taking advantage by a multimedia tool (MEDEA), tracing a guided procedure useful for seismic safety check evaluation and post event macroseismic assessment. A list of the possible collapse mechanisms observed in the post event surveys on masonry structures and a complete abacus of the damages are provided in MEDEA. In this tool a possible combination between a set of damage typologies and each collapse mechanism is supplied in order to improve the homogeneity of the damages interpretation. On the other hand recent researches of one of the author have selected a number of possible typological vulnerability factors of masonry buildings, these are listed in the paper and combined with potential collapse mechanisms to be activated under seismic excitation. The procedure takes place from simple structural behavior models, derived from the Umbria-Marche earthquake observations, and tested after the San Giuliano di Puglia event; it provides the basis either for safety check analyses of the existing buildings or for post-event structural safety assessment and economic damage evaluation. In the paper taking advantage of MEDEA mechanisms analysis, mainly developed for the post event safety check surveyors training, a simple logic path is traced in order to approach the evaluation of the masonry building safety check. The procedure starts from the identification of the typological vulnerability factors to derive the potential collapse mechanisms and their collapse multipliers and finally addresses the simplest and cheapest strengthening techniques to reduce the original vulnerability. The procedure has been introduced in the Guide Lines of the Regione Campania for the professionals in charge of the safety check analyses and the buildings strengthening in application of the national mitigation campaign introduced by the Ordinance of the Central Government n. 3362

  12. Various forms of indexing HDMR for modelling multivariate classification problems

    SciTech Connect

    Aksu, a?r?; Tunga, M. Alper

    2014-12-10

    The Indexing HDMR method was recently developed for modelling multivariate interpolation problems. The method uses the Plain HDMR philosophy in partitioning the given multivariate data set into less variate data sets and then constructing an analytical structure through these partitioned data sets to represent the given multidimensional problem. Indexing HDMR makes HDMR be applicable to classification problems having real world data. Mostly, we do not know all possible class values in the domain of the given problem, that is, we have a non-orthogonal data structure. However, Plain HDMR needs an orthogonal data structure in the given problem to be modelled. In this sense, the main idea of this work is to offer various forms of Indexing HDMR to successfully model these real life classification problems. To test these different forms, several well-known multivariate classification problems given in UCI Machine Learning Repository were used and it was observed that the accuracy results lie between 80% and 95% which are very satisfactory.

  13. Decreased cell survival and DNA repair capacity after UVC irradiation in association with down-regulation of GRP78/BiP in human RSa cells

    SciTech Connect

    Zhai Ling; Kita, Kazuko . E-mail: kita@faculty.chiba-u.jp; Wano, Chieko; Wu Yuping; Sugaya, Shigeru; Suzuki, Nobuo

    2005-05-01

    In contrast to extensive studies on the roles of molecular chaperones, such as heat shock proteins, there are only a few reports about the roles of GRP78/BiP, an endoplasmic reticulum (ER) stress-induced molecular chaperone, in mammalian cell responses to DNA-damaging stresses. To investigate whether GRP78/BiP is involved in resistance to a DNA-damaging agent, UVC (principally 254 nm in wavelength), we established human cells with down-regulation of GRP78/BiP by transfection of human RSa cells with antisense cDNA for GRP78/BiP. We found that the transfected cells showed higher sensitivity to UVC-induced cell death than control cells transfected with the vector alone. In the antisense-cDNA transfected cells, the removal capacities of the two major types of UVC-damaged DNA (thymine dimers and (6-4) photoproducts) in vivo and DNA synthesis activity of whole cell extracts to repair UVC-irradiated plasmids in vitro were remarkably decreased compared with those in the control cells. Furthermore, the antisense-cDNA transfected cells also showed slightly higher sensitivity to cisplatin-induced cell death than the control cells. Cisplatin-induced DNA damage is primarily repaired by nucleotide excision repair, like UVC-induced DNA damage. The present results suggest that GRP78/BiP plays a protective role against UVC-induced cell death possibly via nucleotide excision repair, at least in the human RSa cells tested.

  14. Benchmarking for electric utilities, tree trimming benchmarking, service line installation to single family residence, and distribution revenue meter testing and repair

    SciTech Connect

    Harder, J.

    1994-12-31

    An American Public Power Association (APPA) task force study on benchmarking for electric utilities is presented. Benchmark studies were made of three activities: (1) Tree trimming; (2) Service line installation to single family residence; (3) Distribution revenue meter testing and repair criteria. The results of the study areas are summarized for 15 utilities. The methodologies used for data collection and analysis are discussed. 28 figs., 9 tabs.

  15. Study to develop an inspection, maintenance, and repair plan for OTEC (Ocean Thermal Energy Conversion) modular experiment plants. Final report

    SciTech Connect

    Not Available

    1980-04-01

    The inspection, maintenance and repair (IM and R) of the Ocean Thermal Energy Conversion (OTEC) Modular Experiment Plant (Pilot Plant) have been studied in two phases: Task I and Task II. Task I phase developed IM and R identification forms, identified requirements for routine and post casualty IM and R, and categorized and outlined potential procedures to perform IM and R activities. The efforts of the Task II phase have been directed to meet the following objectives: to provide feedback to the OTEC marine systems designs to assure that such designs reflect appropriate consideration of IM and R methods and unit costs, resulting in designs with reduced life cycle costs; to include technical information concerning OTEC IM and R possibilities to NOAA/DOE; to outline a basis in which the anticipated IM and R contributions to life cycle costs can be developed for any specific OTEC plant design; to identify IM and R methods within the state-of-the-art in the offshore industry; to determine the application of potential IM and R procedures for the commercial operation of OTEC 10/40 Pilot Plant(s); and input into the US government formulation of statutory and regulatory IM and R requirements for OTEC plants.

  16. State-of-the-art review of materials-related problems in flue gas desulfurization systems

    SciTech Connect

    Maiya, P. S.

    1980-10-01

    This report characterizes the chemical and mechanical environments to which the structural components used in flue-gas desulfurization (FGD) are exposed. It summarizes the necessary background information pertinent to various FGD processes currently in use, with particular emphasis on lime/limestone scrubbing technology, so that the materials problems and processing variables encountered in FGD systems can be better defined and appreciated. The report also describes the materials currently used and their performance to date in existing wet scrubbers. There is little doubt that with more extensive use of coal and flue-gas scrubbers by utilities and other segments of private industry, a better understanding of the material failure mechanisms, performance limitations, and potential problem areas is required for the design of more reliable and cost-effective FGD systems. To meet the above objectives, a materials evaluation program is proposed. The important experimental variables and the number of tests required to evaluate a given material are discussed. 55 references, 9 figures, 6 tables.

  17. Micro electro-mechanical heater

    DOEpatents

    Oh, Yunje; Asif, Syed Amanulla Syed; Cyrankowski, Edward; Warren, Oden Lee

    2016-04-19

    A sub-micron scale property testing apparatus including a test subject holder and heating assembly. The assembly includes a holder base configured to couple with a sub-micron mechanical testing instrument and electro-mechanical transducer assembly. The assembly further includes a test subject stage coupled with the holder base. The test subject stage is thermally isolated from the holder base. The test subject stage includes a stage subject surface configured to receive a test subject, and a stage plate bracing the stage subject surface. The stage plate is under the stage subject surface. The test subject stage further includes a heating element adjacent to the stage subject surface, the heating element is configured to generate heat at the stage subject surface.

  18. Chemically assisted mechanical refrigeration process

    DOEpatents

    Vobach, Arnold R.

    1987-01-01

    There is provided a chemically assisted mechanical refrigeration process including the steps of: mechanically compressing a refrigerant stream which includes vaporized refrigerant; contacting the refrigerant with a solvent in a mixer (11) at a pressure sufficient to promote substantial dissolving of the refrigerant in the solvent in the mixer (11) to form a refrigerant-solvent solution while concurrently placing the solution in heat exchange relation with a working medium to transfer energy to the working medium, said refrigerant-solvent solution exhibiting a negative deviation from Raoult's Law; reducing the pressure over the refrigerant-solvent solution in an evaporator (10) to allow the refrigerant to vaporize and substantially separate from the solvent while concurrently placing the evolving refrigerant-solvent solution in heat exchange relation with a working medium to remove energy from the working medium to thereby form a refrigerant stream and a solvent stream; and passing the solvent and refrigerant stream from the evaporator.

  19. Chemically assisted mechanical refrigeration process

    DOEpatents

    Vobach, Arnold R.

    1987-01-01

    There is provided a chemically assisted mechanical refrigeration process including the steps of: mechanically compressing a refrigerant stream which includes vaporized refrigerant; contacting the refrigerant with a solvent in a mixer (11) at a pressure sufficient to promote substantial dissolving of the refrigerant in the solvent in the mixer (11) to form a refrigerant-solvent solution while concurrently placing the solution in heat exchange relation with a working medium to transfer energy to the working medium, said refrigerant-solvent solution exhibiting a negative deviation from Raoult's Law; reducing the pressure over the refrigerant-solvent solution in an evaporator (10) to allow the refrigerant to vaporize and substantially separate from the solvent while concurrently placing he evolving refrigerant-solvent solution in heat exchange relation with a working medium to remove energy from the working medium to thereby form a refrigerant stream and a solvent stream; and passing the solvent and refrigerant stream from the evaporator.

  20. Chemically assisted mechanical refrigeration process

    DOEpatents

    Vobach, A.R.

    1987-11-24

    There is provided a chemically assisted mechanical refrigeration process including the steps of: mechanically compressing a refrigerant stream which includes vaporized refrigerant; contacting the refrigerant with a solvent in a mixer at a pressure sufficient to promote substantial dissolving of the refrigerant in the solvent in the mixer to form a refrigerant-solvent solution while concurrently placing the solution in heat exchange relation with a working medium to transfer energy to the working medium, said refrigerant-solvent solution exhibiting a negative deviation from Raoult's Law; reducing the pressure over the refrigerant-solvent solution in an evaporator to allow the refrigerant to vaporize and substantially separate from the solvent while concurrently placing the evolving refrigerant-solvent solution in heat exchange relation with a working medium to remove energy from the working medium to thereby form a refrigerant stream and a solvent stream; and passing the solvent and refrigerant stream from the evaporator. 5 figs.

  1. Chemically assisted mechanical refrigeration process

    DOEpatents

    Vobach, A.R.

    1987-06-23

    There is provided a chemically assisted mechanical refrigeration process including the steps of: mechanically compressing a refrigerant stream which includes vaporized refrigerant; contacting the refrigerant with a solvent in a mixer at a pressure sufficient to promote substantial dissolving of the refrigerant in the solvent in the mixer to form a refrigerant-solvent solution while concurrently placing the solution in heat exchange relation with a working medium to transfer energy to the working medium, said refrigerant-solvent solution exhibiting a negative deviation from Raoult's Law; reducing the pressure over the refrigerant-solvent solution in an evaporator to allow the refrigerant to vaporize and substantially separate from the solvent while concurrently placing the evolving refrigerant-solvent solution in heat exchange relation with a working medium to remove energy from the working medium to thereby form a refrigerant stream and a solvent stream; and passing the solvent and refrigerant stream from the evaporator. 5 figs.

  2. Locking mechanism for indexing device

    DOEpatents

    Lindemeyer, Carl W. (Aurora, IL)

    1984-01-01

    Disclosed is a locking mechanism for an indexing spindle. A conventional r gear having outwardly extending teeth is affixed to the spindle. Also included is a rotatably mounted camshaft whose axis is arranged in skewed relationship with the axis of the spindle. A disk-like wedge having opposing camming surfaces is eccentrically mounted on the camshaft. As the camshaft is rotated, the camming surfaces of the disc-like member are interposed between adjacent gear teeth with a wiping action that wedges the disc-like member between the gear teeth. A zero backlash engagement between disc-like member and gear results, with the engagement having a high mechanical advantage so as to effectively lock the spindle against bidirectional rotation.

  3. Mechanical Properties of Niobium Cavities

    SciTech Connect

    Ciovati, Gianluigi; Dhakal, Pashupati; Matalevich, Joseph R.; Myneni, Ganapati Rao

    2015-09-01

    The mechanical stability of bulk Nb cavity is an important aspect to be considered in relation to cavity material, geometry and treatments. Mechanical properties of Nb are typically obtained from uniaxial tensile tests of small samples. In this contribution we report the results of measurements of the resonant frequency and local strain along the contour of single-cell cavities made of ingot and fine-grain Nb of different purity subjected to increasing uniform differential pressure, up to 6 atm. Measurements have been done on cavities subjected to different heat treatments. Good agreement between finite element analysis simulations and experimental data in the elastic regime was obtained with a single set of values of Young’s modulus and Poisson’s ratio. The experimental results indicate that the yield strength of medium-purity ingot Nb cavities is higher than that of fine-grain, high-purity Nb.

  4. Robust Consumption-Investment Problem on Infinite Horizon

    SciTech Connect

    Zawisza, Dariusz

    2015-12-15

    In our paper we consider an infinite horizon consumption-investment problem under a model misspecification in a general stochastic factor model. We formulate the problem as a stochastic game and finally characterize the saddle point and the value function of that game using an ODE of semilinear type, for which we provide a proof of an existence and uniqueness theorem for its solution. Such equation is interested on its own right, since it generalizes many other equations arising in various infinite horizon optimization problems.

  5. Nonlinear eigenvalue problems in Density Functional Theory calculations

    SciTech Connect

    Fattebert, J

    2009-08-28

    Developed in the 1960's by W. Kohn and coauthors, Density Functional Theory (DFT) is a very popular quantum model for First-Principles simulations in chemistry and material sciences. It allows calculations of systems made of hundreds of atoms. Indeed DFT reduces the 3N-dimensional Schroedinger electronic structure problem to the search for a ground state electronic density in 3D. In practice it leads to the search for N electronic wave functions solutions of an energy minimization problem in 3D, or equivalently the solution of an eigenvalue problem with a non-linear operator.

  6. Mechanical Engineering Department Technical Review

    SciTech Connect

    Carr, R.B.; Denney, R.M.

    1981-07-01

    The Mechanical Engineering Department Technical Review is published to inform readers of various technical activities within the Department, promote exchange of ideas, and give credit to personnel who are achieving the results. The report is presented in two parts: technical achievements and publication abstracts. The first is divided into seven sections, each of which reports on an engineering division and its specific activities related to nuclear tests, nuclear explosives, weapons, energy systems, engineering sciences, magnetic fusion, and materials fabrication.

  7. Mechanical engineering department technical review

    SciTech Connect

    Carr, R.B. Denney, R.M.

    1981-01-01

    The Mechanical Engineering Department Technical Review is published to: (1) inform the readers of various technical activities within the department, (2) promote exchange of ideas, and (3) give credit to the personnel who are achieving the results. The report is formatted into two parts: technical acievements and publication abstracts. The first is divided into eight sections, one for each division in the department providing the reader with the names of the personnel and the division accomplishing the work.

  8. GUI for Structural Mechanics Codes

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Development of GUI for Structural Mechanics Codes The TRACC Cluster gives its users a lot of flexibility when it comes to requesting software version of LS-DYNA and computational resources for submitted jobs. To fully utilize that flexibility, users need to get familiar with on-line documentation of all the installed releases of different software and modules on the cluster. As on other LINUX based HPC systems, the submission and controlling of LS-DYNA is done through text commands. Especially

  9. Mechanical Engineering Department technical abstracts

    SciTech Connect

    Denney, R.M.

    1982-07-01

    The Mechanical Engineering Department publishes listings of technical abstracts twice a year to inform readers of the broad range of technical activities in the Department, and to promote an exchange of ideas. Details of the work covered by an abstract may be obtained by contacting the author(s). Overall information about current activities of each of the Department's seven divisions precedes the technical abstracts.

  10. Particle Suspension Mechanisms - Supplemental Material

    SciTech Connect

    Dillon, M B

    2011-03-03

    This supplemental material provides a brief introduction to particle suspension mechanisms that cause exfoliated skin cells to become and remain airborne. The material presented here provides additional context to the primary manuscript and serves as background for designing possible future studies to assess the impact of skin cells as a source of infectious aerosols. This introduction is not intended to be comprehensive and interested readers are encouraged to consult the references cited.

  11. Electric drive mechanism for vehicles

    SciTech Connect

    Bader, C.

    1983-06-21

    An electric drive mechanism is disclosed for vehicles, especially buses with overhead trolley routes, which routes are provided with relatively short interruptions in the overhead trolley. The drive mechanism includes a flywheel two externally excited electric motors which are adapted to be switched over from prime mover operation to generator operation, and which motors are effective as a ward-leonard drive during flywheel operation. The first electric motor is constructed for half of a maximum drive power and the second electric motor is likewise constructed for half or for square root 2/2 times the maximum drive power. Both electric motors are connected electrically in parallel during operation from the main electrical supply. The first and second motors are electrically connected in parallel during operation of the vehicle from the main electrical supply when a change-speed transmission is provided for connecting a drive shaft of one of the motors with driven vehicle wheels. A planetary gear transmission and a further transmission are provided for mechanically connecting the drive shaft of one of the motors with the second motor and with the flywheel.

  12. Mechanism of instantaneous coal outbursts

    SciTech Connect

    Guan, P.; Wang, H.Y.; Zhang, Y.X.

    2009-10-15

    Thousands of mine workers die every year from mining accidents, and instantaneous coal outbursts in underground coal mines are one of the major killers. Various models for these outbursts have been proposed, but the precise mechanism is still unknown. We hypothesize that the mechanism of coal outbursts is similar to magma fragmentation during explosive volcanic eruptions; i.e., it is caused by high gas pressure inside coal but low ambient pressure on it, breaking coal into pieces and releasing the high-pressure gas in a shock wave. Hence, coal outbursts may be regarded as another type of gas-driven eruption, in addition to explosive volcanic, lake, and possible ocean eruptions. We verify the hypothesis by experiments using a shock-tube apparatus. Knowing the mechanism of coal outbursts is the first step in developing prediction and mitigation measures. The new concept of gas-driven solid eruption is also important to a better understanding of salt-gas outbursts, rock-gas outbursts, and mud volcano eruptions.

  13. Quantum mechanical method of fragment's angular and energy distribution calculation for binary and ternary fission

    SciTech Connect

    Kadmensky, S. G., E-mail: kadmensky@phys.vsu.ru; Titova, L. V.; Pen'kov, N. V. [Voronezh State University (Russian Federation)

    2006-08-15

    In the framework of quantum-mechanical fission theory, the method of calculation for partial fission width amplitudes and asymptotic behavior of the fissile nucleus wave function with strong channel coupling taken into account has been suggested. The method allows one to solve the calculation problem of angular and energy distribution countation for binary and ternary fission.

  14. Domain decomposition methods for solving an image problem

    SciTech Connect

    Tsui, W.K.; Tong, C.S.

    1994-12-31

    The domain decomposition method is a technique to break up a problem so that ensuing sub-problems can be solved on a parallel computer. In order to improve the convergence rate of the capacitance systems, pre-conditioned conjugate gradient methods are commonly used. In the last decade, most of the efficient preconditioners are based on elliptic partial differential equations which are particularly useful for solving elliptic partial differential equations. In this paper, the authors apply the so called covering preconditioner, which is based on the information of the operator under investigation. Therefore, it is good for various kinds of applications, specifically, they shall apply the preconditioned domain decomposition method for solving an image restoration problem. The image restoration problem is to extract an original image which has been degraded by a known convolution process and additive Gaussian noise.

  15. A Schwarz alternating procedure for singular perturbation problems

    SciTech Connect

    Garbey, M.; Kaper, H.G.

    1994-12-31

    The authors show that the Schwarz alternating procedure offers a good algorithm for the numerical solution of singular perturbation problems, provided the domain decomposition is properly designed to resolve the boundary and transition layers. They give sharp estimates for the optimal position of the domain boundaries and present convergence rates of the algorithm for various second-order singular perturbation problems. The splitting of the operator is domain-dependent, and the iterative solution of each subproblem is based on a modified asymptotic expansion of the operator. They show that this asymptotic-induced method leads to a family of efficient massively parallel algorithms and report on implementation results for a turning-point problem and a combustion problem.

  16. ALCF's new data science program targets "big data" problems ...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    ALCF's new data science program targets "big data" problems Author: Laura Wolf April 1, 2016 Facebook Twitter LinkedIn Google E-mail Printer-friendly version The Argonne Leadership ...

  17. Accelerating PDE-Constrained Optimization Problems using Adaptive...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Accelerating PDE-Constrained Optimization Problems using Adaptive Reduced-Order Models January 15, 2016 10:30AM to 11:30AM Presenter Matthew Zahr, Wilkinson Interviewee Location...

  18. "Upcycling": A Green Solution to the Problem of Plastic - Energy...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Find More Like This Return to Search "Upcycling": A Green Solution to the Problem of ... At Argonne, chemist Vilas Pol has devised an environmentally green method that breaks down ...

  19. Simulation and Analysis of Converging Shock Wave Test Problems

    SciTech Connect

    Ramsey, Scott D.; Shashkov, Mikhail J.

    2012-06-21

    Results and analysis pertaining to the simulation of the Guderley converging shock wave test problem (and associated code verification hydrodynamics test problems involving converging shock waves) in the LANL ASC radiation-hydrodynamics code xRAGE are presented. One-dimensional (1D) spherical and two-dimensional (2D) axi-symmetric geometric setups are utilized and evaluated in this study, as is an instantiation of the xRAGE adaptive mesh refinement capability. For the 2D simulations, a 'Surrogate Guderley' test problem is developed and used to obviate subtleties inherent to the true Guderley solution's initialization on a square grid, while still maintaining a high degree of fidelity to the original problem, and minimally straining the general credibility of associated analysis and conclusions.

  20. Piezoelectrically enhanced ferroelectric polymers via nanoscale mechanical

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    annealing | Argonne National Laboratory Vertical piezoresponse hysteresis loops in pristine and mechanically annealed regions. Vertical piezoresponse hysteresis loops in pristine and mechanically annealed regions. Piezoelectrically enhanced ferroelectric polymers via nanoscale mechanical annealing May 13, 2015 Tweet EmailPrint Scientific Achievement We developed a nanoscale mechanical annealing process of polymer ferroelectric thin films, which can control nanoscale material properties and

  1. Concentrating Solar Power: Efficiently Leveraging Equilibrium Mechanisms

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    for Engineering New Thermochemical Storage | Department of Energy Efficiently Leveraging Equilibrium Mechanisms for Engineering New Thermochemical Storage Concentrating Solar Power: Efficiently Leveraging Equilibrium Mechanisms for Engineering New Thermochemical Storage Concentrating Solar Power: Efficiently Leveraging Equilibrium Mechanisms for Engineering New Thermochemical Storage The Concentrating Solar Power: Efficiently Leveraging Equilibrium Mechanisms for Engineering New

  2. The problem of living in a world contaminated with chemicals

    SciTech Connect

    Metcalf, R.L.

    1990-12-31

    The proliferation of xenobiotic chemicals in the global environment poses living problems for each of us aboard {open_quotes}spaceship earth.{close_quotes} Seven case studies are presented that illustrate the magnitude of the problem that can result from waiting to identify toxic hazards until there have been decades of {open_quotes}human guinea pig{close_quotes} exposure. 25 refs., 5 tabs.

  3. Construction of nerve guide conduits from cellulose/soy protein composite membranes combined with Schwann cells and pyrroloquinoline quinone for the repair of peripheral nerve defect

    SciTech Connect

    Luo, Lihua; Gan, Li; Liu, Yongming; Tian, Weiqun; Tong, Zan; Wang, Xiong; Huselstein, Celine; Chen, Yun

    2015-02-20

    Regeneration and functional reconstruction of peripheral nerve defects remained a significant clinical challenge. Nerve guide conduits, with seed cells or neurotrophic factors (NTFs), had been widely used to improve the repair and regeneration of injured peripheral nerve. Pyrroloquinoline quinone (PQQ) was an antioxidant that can stimulate nerve growth factors (NGFs) synthesis and accelerate the Schwann cells (SCs) proliferation and growth. In present study, three kinds of nerve guide conduits were constructed: one from cellulose/SPI hollow tube (CSC), another from CSC combined with SCs (CSSC), and the third one from CSSC combined with PQQ (CSSPC), respectively. And then they were applied to bridge and repair the sciatic nerve defect in rats, using autograft as control. Effects of different nerve guide conduits on the nerve regeneration were comparatively evaluated by general analysis, sciatic function index (SFI) and histological analysis (HE and TEM). Newly-formed regenerative nerve fibers were observed and running through the transparent nerve guide conduits 12 weeks after surgery. SFI results indicated that the reconstruction of motor function in CSSPC group was better than that in CSSC and CSC groups. HE images from the cross-sections and longitudinal-sections of the harvested regenerative nerve indicated that regenerative nerve fibers had been formed and accompanied with new blood vessels and matrix materials in the conduits. TEM images also showed that lots of fresh myelinated and non-myelinated nerve fibers had been formed. Parts of vacuolar, swollen and abnormal axons occurred in CSC and CSSC groups, while the vacuolization and swell of axons was the least serious in CSSPC group. These results indicated that CSSPC group had the most ability to repair and reconstruct the nerve structure and functions due to the comprehensive contributions from hollow CSC tube, SCs and PQQ. As a result, the CSSPC may have the potential for the applications as nerve guide

  4. Capacitated arc routing problem and its extensions in waste collection

    SciTech Connect

    Fadzli, Mohammad; Najwa, Nurul; Luis, Martino

    2015-05-15

    Capacitated arc routing problem (CARP) is the youngest generation of graph theory that focuses on solving the edge/arc routing for optimality. Since many years, operational research devoted to CARP counterpart, known as vehicle routing problem (VRP), which does not fit to several real cases such like waste collection problem and road maintenance. In this paper, we highlighted several extensions of capacitated arc routing problem (CARP) that represents the real-life problem of vehicle operation in waste collection. By purpose, CARP is designed to find a set of routes for vehicles that satisfies all pre-setting constraints in such that all vehicles must start and end at a depot, service a set of demands on edges (or arcs) exactly once without exceeding the capacity, thus the total fleet cost is minimized. We also addressed the differentiation between CARP and VRP in waste collection. Several issues have been discussed including stochastic demands and time window problems in order to show the complexity and importance of CARP in the related industry. A mathematical model of CARP and its new version is presented by considering several factors such like delivery cost, lateness penalty and delivery time.

  5. Geothermal drilling problems and their impact on cost

    SciTech Connect

    Carson, C.C.

    1982-01-01

    Historical data are presented that demonstrate the significance of unexpected problems. In extreme cases, trouble costs are the largest component of well costs or severe troubles can lead to abandonment of a hole. Drilling experiences from US geothermal areas are used to analyze the frequency and severity of various problems. In addition, average trouble costs are estimated based on this analysis and the relationship between trouble and depth is discussed. The most frequent drilling and completion problem in geothermal wells is lost circulation. This is especially true for resources in underpressured, fractured formations. Serious loss of circulation can occur during drilling - because of this, the producing portions of many wells are drilled with air or aerated drilling fluid and the resulting corrosion/erosion problems are tolerated - but it can also affect the cementing of well casing. Problems in bonding the casing to the formation result from many other causes as well, and are common in geothermal wells. Good bonds are essential because of the possibility of casing collapse due to thermal cycling during the life of the well. Several other problems are identified and their impacts are quantified and discussed.

  6. Mesoscale Benchmark Demonstration Problem 1: Mesoscale Simulations of Intra-granular Fission Gas Bubbles in UO2 under Post-irradiation Thermal Annealing

    SciTech Connect

    Li, Yulan; Hu, Shenyang Y.; Montgomery, Robert; Gao, Fei; Sun, Xin; Tonks, Michael; Biner, Bullent; Millet, Paul; Tikare, Veena; Radhakrishnan, Balasubramaniam; Andersson , David

    2012-04-11

    A study was conducted to evaluate the capabilities of different numerical methods used to represent microstructure behavior at the mesoscale for irradiated material using an idealized benchmark problem. The purpose of the mesoscale benchmark problem was to provide a common basis to assess several mesoscale methods with the objective of identifying the strengths and areas of improvement in the predictive modeling of microstructure evolution. In this work, mesoscale models (phase-field, Potts, and kinetic Monte Carlo) developed by PNNL, INL, SNL, and ORNL were used to calculate the evolution kinetics of intra-granular fission gas bubbles in UO2 fuel under post-irradiation thermal annealing conditions. The benchmark problem was constructed to include important microstructural evolution mechanisms on the kinetics of intra-granular fission gas bubble behavior such as the atomic diffusion of Xe atoms, U vacancies, and O vacancies, the effect of vacancy capture and emission from defects, and the elastic interaction of non-equilibrium gas bubbles. An idealized set of assumptions was imposed on the benchmark problem to simplify the mechanisms considered. The capability and numerical efficiency of different models are compared against selected experimental and simulation results. These comparisons find that the phase-field methods, by the nature of the free energy formulation, are able to represent a larger subset of the mechanisms influencing the intra-granular bubble growth and coarsening mechanisms in the idealized benchmark problem as compared to the Potts and kinetic Monte Carlo methods. It is recognized that the mesoscale benchmark problem as formulated does not specifically highlight the strengths of the discrete particle modeling used in the Potts and kinetic Monte Carlo methods. Future efforts are recommended to construct increasingly more complex mesoscale benchmark problems to further verify and validate the predictive capabilities of the mesoscale modeling

  7. DOE fundamentals handbook: Mechanical science. Volume 2

    SciTech Connect

    Not Available

    1993-01-01

    The Mechanical Science Handbook was developed to assist nuclear facility operating contractors in providing operators, maintenance personnel, and the technical staff with the necessary fundamentals training to ensure a basic understanding of mechanical components and mechanical science. The handbook includes information diesel engines, heat exchangers, pumps, valves, and miscellaneous mechanical components. This information will provide personnel with a foundation for understanding the construction and operation of mechanical components that are associated with various DOE nuclear facility operations and maintenance.

  8. How reclamation tests mechanical governors

    SciTech Connect

    Agee, J.C.; Girgis, G.K.; Cline, R.

    1996-08-01

    The Bureau of Reclamation has developed its own equipment for testing mechanical-hydraulic governors for hydroelectric generators. The device, called a Permanent Magnet Generator (PMG) Simulator, generates a three-phase voltage that will drive the governor ballhead motor at variable speed. Utilizing this equipment, most traditional governor tests can be completed with the generating unit dewatered. In addition, frequency response testing and other detailed analytical tests can be performed to validate governor models. This article describes the development and design of the equipment, and it also discusses its usage in a case study of events at Glen Canyon Dam.

  9. Tank waste concentration mechanism study

    SciTech Connect

    Pan, L.C.; Johnson, L.J.

    1994-09-01

    This study determines whether the existing 242-A Evaporator should continue to be used to concentrate the Hanford Site radioactive liquid tank wastes or be replaced by an alternative waste concentration process. Using the same philosophy, the study also determines what the waste concentration mechanism should be for the future TWRS program. Excess water from liquid DST waste should be removed to reduce the volume of waste feed for pretreatment, immobilization, and to free up storage capacity in existing tanks to support interim stabilization of SSTS, terminal cleanout of excess facilities, and other site remediation activities.

  10. Controlled Thermo-Mechanical Processing

    SciTech Connect

    None

    2005-09-01

    The CTMP technology has the potential for widespread application in all major sectors of the domestic tube and pipe industry; two of the largest sectors are seamless mechanical tubing and seamless oil country tubular goods. It has been proven for the spheroidized annealing heat cycle for through-hardened steels and has led to the development of a recipe for automotive gear steels. Potential applications also exist in the smaller sectors of seamless line pipe, pressure tubing, and stainless tubing. The technology could also apply to non-ferrous metal industries, such as titanium.

  11. Mechanical accessories for mobile teleoperators

    SciTech Connect

    Feldman, M.J.; Herndon, J.N.

    1985-01-01

    The choice of optimum mechanical accessories for mobile teleoperators involves matching the criteria for emergency response with the available technology. This paper presents a general background to teleoperations, a potpourri of the manipulator systems available, and an argument for force reflecting manipulation. The theme presented is that the accomplishment of humanlike endeavors in hostile environments will be most successful when man model capabilities are utilized. The application of recent electronic technology to manipulator development has made new tools available to be applied to emergency response activities. The development activities described are products of the Consolidated Fuel Reprocessing Program at the Oak Ridge National Laboratory. 13 refs., 7 figs.

  12. Application of the FETI Method to ASCI Problems: Scalability Results on One Thousand Processors and Discussion of Highly Heterogeneous Problems

    SciTech Connect

    Bhardwaj, M.; Day, D.; Farhat, C.; Lesoinne, M; Pierson, K.; Rixen, D.

    1999-04-01

    We report on the application of the one-level FETI method to the solution of a class of substructural problems associated with the Department of Energy's Accelerated Strategic Computing Initiative (ASCI). We focus on numerical and parallel scalability issues, and on preliminary performance results obtained on the ASCI Option Red supercomputer configured with as many as one thousand processors, for problems with as many as 5 million degrees of freedom.

  13. What is behind small deviations of quantum mechanics theory from experiments? Observer's mathematics point of view

    SciTech Connect

    Khots, Boris; Khots, Dmitriy

    2014-12-10

    Certain results that have been predicted by Quantum Mechanics (QM) theory are not always supported by experiments. This defines a deep crisis in contemporary physics and, in particular, quantum mechanics. We believe that, in fact, the mathematical apparatus employed within today's physics is a possible reason. In particular, we consider the concept of infinity that exists in today's mathematics as the root cause of this problem. We have created Observer's Mathematics that offers an alternative to contemporary mathematics. This paper is an attempt to relay how Observer's Mathematics may explain some of the contradictions in QM theory results. We consider the Hamiltonian Mechanics, Newton equation, Schrodinger equation, two slit interference, wave-particle duality for single photons, uncertainty principle, Dirac equations for free electron in a setting of arithmetic, algebra, and topology provided by Observer's Mathematics (see www.mathrelativity.com). Certain results and communications pertaining to solution of these problems are provided.

  14. SEACAS Theory Manuals: Part III. Finite Element Analysis in Nonlinear Solid Mechanics

    SciTech Connect

    Laursen, T.A.; Attaway, S.W.; Zadoks, R.I.

    1999-03-01

    This report outlines the application of finite element methodology to large deformation solid mechanics problems, detailing also some of the key technological issues that effective finite element formulations must address. The presentation is organized into three major portions: first, a discussion of finite element discretization from the global point of view, emphasizing the relationship between a virtual work principle and the associated fully discrete system, second, a discussion of finite element technology, emphasizing the important theoretical and practical features associated with an individual finite element; and third, detailed description of specific elements that enjoy widespread use, providing some examples of the theoretical ideas already described. Descriptions of problem formulation in nonlinear solid mechanics, nonlinear continuum mechanics, and constitutive modeling are given in three companion reports.

  15. Endovascular Aortic Aneurysm Repair with the Talent Stent-Graft: Outcomes in Patients with Large Iliac Arteries

    SciTech Connect

    England, Andrew; Butterfield, John S.; McCollum, Charles N.; Ashleigh, Raymond J.

    2008-07-15

    The purpose of this study is to report outcomes following endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA) in patients with ectatic common iliac arteries (CIAs). Of 117 AAA patients treated by EVAR between 1998 and 2005, 87 (74%) had CIAs diameters <18 mm and 30 (26%) patients had one or more CIA diameters >18 but <25 mm. All patients were treated with Talent stent-grafts, 114 bifurcated and 3 AUI devices. Departmental databases and patient records were reviewed to assess outcomes. Technical success, iliac-related outcome, and iliac-related reintervention (IRSI) were analyzed. Patients with EVAR extending into the external iliac artery were excluded. Median (range) follow-up for the study group was 24 (1-84) months. Initial technical success was 98% for CIAs <18 mm and 100% for CIAs {>=}18 mm (p = 0.551). There were three distal type I endoleaks (two in the ectatic group) and six iliac limb occlusions (one in an ectatic patient); there were no statistically significant differences between groups (p = 0.4). There were nine IRSIs (three stent-graft extensions, six femorofemoral crossover grafts); three of these patients had one or both CIAs {>=}18 mm (p = 0.232). One-year freedom from IRSI was 92% {+-} 3% and 84% {+-} 9% for the <18-mm and {>=}18-mm CIA groups, respectively (p = 0.232). We conclude that the treatment of AAA by EVAR in patients with CIAs 18-24 mm appears to be safe and effective, however, it may be associated with more frequent reinterventions.

  16. Maximum Diameter Measurements of Aortic Aneurysms on Axial CT Images After Endovascular Aneurysm Repair: Sufficient for Follow-up?

    SciTech Connect

    Baumueller, Stephan Nguyen, Thi Dan Linh Goetti, Robert Paul; Lachat, Mario; Seifert, Burkhardt; Pfammatter, Thomas Frauenfelder, Thomas

    2011-12-15

    Purpose: To assess the accuracy of maximum diameter measurements of aortic aneurysms after endovascular aneurysm repair (EVAR) on axial computed tomographic (CT) images in comparison to maximum diameter measurements perpendicular to the intravascular centerline for follow-up by using three-dimensional (3D) volume measurements as the reference standard. Materials and Methods: Forty-nine consecutive patients (73 {+-} 7.5 years, range 51-88 years), who underwent EVAR of an infrarenal aortic aneurysm were retrospectively included. Two blinded readers twice independently measured the maximum aneurysm diameter on axial CT images performed at discharge, and at 1 and 2 years after intervention. The maximum diameter perpendicular to the centerline was automatically measured. Volumes of the aortic aneurysms were calculated by dedicated semiautomated 3D segmentation software (3surgery, 3mensio, the Netherlands). Changes in diameter of 0.5 cm and in volume of 10% were considered clinically significant. Intra- and interobserver agreements were calculated by intraclass correlations (ICC) in a random effects analysis of variance. The two unidimensional measurement methods were correlated to the reference standard. Results: Intra- and interobserver agreements for maximum aneurysm diameter measurements were excellent (ICC = 0.98 and ICC = 0.96, respectively). There was an excellent correlation between maximum aneurysm diameters measured on axial CT images and 3D volume measurements (r = 0.93, P < 0.001) as well as between maximum diameter measurements perpendicular to the centerline and 3D volume measurements (r = 0.93, P < 0.001). Conclusion: Measurements of maximum aneurysm diameters on axial CT images are an accurate, reliable, and robust method for follow-up after EVAR and can be used in daily routine.

  17. The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome

    SciTech Connect

    Trego, Kelly S.; Chernikova, Sophia B.; Davalos, Albert R.; Perry, J. Jefferson P.; Finger, L. David; Ng, Cliff; Tsai, Miaw-Sheue; Yannone, Steven M.; Tainer, John A.; Campisi, Judith; Cooper, Priscilla K.

    2011-04-20

    XPG is a structure-specific endonuclease required for nucleotide excision repair (NER). XPG incision defects result in the cancer-prone syndrome xeroderma pigmentosum, whereas truncating mutations of XPG cause the severe postnatal progeroid developmental disorder Cockayne syndrome. We show that XPG interacts directly with WRN protein, which is defective in the premature aging disorder Werner syndrome, and that the two proteins undergo similar sub-nuclear redistribution in S-phase and co-localize in nuclear foci. The co-localization was observed in mid- to late-S-phase, when WRN moves from nucleoli to nuclear foci that have been shown to contain protein markers of both stalled replication forks and telomeric proteins. We mapped the interaction between XPG and WRN to the C-terminal domains of each and show that interaction with the C-terminal domain of XPG strongly stimulates WRN helicase activity. WRN also possesses a competing DNA single-strand annealing activity that, combined with unwinding, has been shown to coordinate regression of model replication forks to form Holliday junction/chicken foot intermediate structures. We tested whether XPG stimulated WRN annealing activity and found that XPG itself has intrinsic strand annealing activity that requires the unstructured R- and C-terminal domains, but not the conserved catalytic core or endonuclease activity. Annealing by XPG is cooperative, rather than additive, with WRN annealing. Taken together, our results suggest a novel function for XPG in S-phase that is at least in part carried out coordinately with WRN, and which may contribute to the severity of the phenotypes that occur upon loss of XPG.

  18. Bellcrank mechanisms for Stirling engines

    SciTech Connect

    Senft, J.R.; Senft, V.J.

    1996-12-31

    This paper describes a family of linkage drive systems for Stirling engines containing several new members. These mechanisms are adaptable to all three configurations of Stirling engine, impose minimal side loads on pistons and displacer rods, and include compact forms suitable for pressurized high performance engines. This group of drive systems is generated by a simple common scheme. Near sinusoidal motion is taken from a crankshaft carrying a single crankpin by two connecting rods each driving a bellcrank. The stationary pivots of the bellcranks are located so that their oscillatory motion has the phase angle separation required between the piston and displacer. The bellcranks are further configured to bring the third pin motion to a location suitable for coupling with the piston or displacer of the engine in a way which minimizes side loading. The paper presents a number of new linkage drives from the dual bellcrank family and indicates how they are embodied in beta and alpha type Stirling engines. The paper includes a design for a small multipurpose engine incorporating one of the subject mechanisms.

  19. COMPLEXITY & APPROXIMABILITY OF QUANTIFIED & STOCHASTIC CONSTRAINT SATISFACTION PROBLEMS

    SciTech Connect

    H. B. HUNT; M. V. MARATHE; R. E. STEARNS

    2001-06-01

    Let D be an arbitrary (not necessarily finite) nonempty set, let C be a finite set of constant symbols denoting arbitrary elements of D, and let S and T be an arbitrary finite set of finite-arity relations on D. We denote the problem of determining the satisfiability of finite conjunctions of relations in S applied to variables (to variables and symbols in C) by SAT(S) (by SATc(S).) Here, we study simultaneously the complexity of decision, counting, maximization and approximate maximization problems, for unquantified, quantified and stochastically quantified formulas. We present simple yet general techniques to characterize simultaneously, the complexity or efficient approximability of a number of versions/variants of the problems SAT(S), Q-SAT(S), S-SAT(S),MAX-Q-SAT(S) etc., for many different such D,C,S,T. These versions/variants include decision, counting, maximization and approximate maximization problems, for unquantified, quantified and stochastically quantified formulas. Our unified approach is based on the following two basic concepts: (i) strongly-local replacements/reductions and (ii) relational/algebraic representability. Some of the results extend the earlier results in [Pa85,LMP99,CF+93,CF+94] Our techniques and results reported here also provide significant steps towards obtaining dichotomy theorems, for a number of the problems above, including the problems MAX-Q-SAT(S), and MAX-S-SAT(S). The discovery of such dichotomy theorems, for unquantified formulas, has received significant recent attention in the literature [CF+93, CF+94, Cr95, KSW97]. Keywords: NP-hardness; Approximation Algorithms; PSPACE-hardness; Quantified and Stochastic Constraint Satisfaction Problems.

  20. The inverse problems of wing panel manufacture processes

    SciTech Connect

    Oleinikov, A. I.; Bormotin, K. S.

    2013-12-16

    It is shown that inverse problems of steady-state creep bending of plates in both the geometrically linear and nonlinear formulations can be represented in a variational formulation. Steady-state values of the obtained functionals corresponding to the solutions of the problems of inelastic deformation and springback are determined by applying a finite element procedure to the functionals. Optimal laws of creep deformation are formulated using the criterion of minimizing damage in the functionals of the inverse problems. The formulated problems are reduced to the problems solved by the finite element method using MSC.Marc software. Currently, forming of light metals poses tremendous challenges due to their low ductility at room temperature and their unusual deformation characteristics at hot-cold work: strong asymmetry between tensile and compressive behavior, and a very pronounced anisotropy. We used the constitutive models of steady-state creep of initially transverse isotropy structural materials the kind of the stress state has influence. The paper gives basics of the developed computer-aided system of design, modeling, and electronic simulation targeting the processes of manufacture of wing integral panels. The modeling results can be used to calculate the die tooling, determine the panel processibility, and control panel rejection in the course of forming.