National Library of Energy BETA

Sample records for developmental assignment evaluation

  1. SESCDP Supervisor's Evaluation of Candidate's Performance During

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Developmental Assignment | Department of Energy SESCDP Supervisor's Evaluation of Candidate's Performance During Developmental Assignment SESCDP Supervisor's Evaluation of Candidate's Performance During Developmental Assignment Form used by SES Supervisor to evaluate a SES candidate's performance in terms of meeting assignment objectives, an overall rating of the candidate's performance, evaluation of executive core qualifications SESCDP Supervisor's Evaluation of Candidate's Performance

  2. Laboratory evaluation of dynamic traffic assignment systems: Requirements, framework, and system design

    SciTech Connect

    Miaou, S.-P.; Pillai, R.S.; Summers, M.S.; Rathi, A.K.; Lieu, H.C.

    1997-01-01

    The success of Advanced Traveler Information 5ystems (ATIS) and Advanced Traffic Management Systems (ATMS) depends on the availability and dissemination of timely and accurate estimates of current and emerging traffic network conditions. Real-time Dynamic Traffic Assignment (DTA) systems are being developed to provide the required timely information. The DTA systems will provide faithful and coherent real-time, pre-trip, and en-route guidance/information which includes routing, mode, and departure time suggestions for use by travelers, ATIS, and ATMS. To ensure the credibility and deployment potential of such DTA systems, an evaluation system supporting all phases of DTA system development has been designed and presented in this paper. This evaluation system is called the DTA System Laboratory (DSL). A major component of the DSL is a ground- truth simulator, the DTA Evaluation System (DES). The DES is envisioned to be a virtual representation of a transportation system in which ATMS and ATIS technologies are deployed. It simulates the driving and decision-making behavior of travelers in response to ATIS and ATMS guidance, information, and control. This paper presents the major evaluation requirements for a DTA Systems, a modular modeling framework for the DES, and a distributed DES design. The modeling framework for the DES is modular, meets the requirements, can be assembled using both legacy and independently developed modules, and can be implemented as a either a single process or a distributed system. The distributed design is extendible, provides for the optimization of distributed performance, and object-oriented design within each distributed component. A status report on the development of the DES and other research applications is also provided.

  3. Parameter assignments for spectral gamma-ray borehole calibration models. National Uranium Resource Evaluation

    SciTech Connect

    Heistand, B.E.; Novak, E.F.

    1984-04-01

    This report documents the work performed to determine the newly assigned concentrations for the spectral gamma-ray borehole calibration models. Thirty-two models, maintained by the US Department of Energy, are included in this study, and are grouped into eight sets of four models each. The eight sets are located at sites across the United States, and are used to calibrate logging instruments. The assignments are based on in-situ logging data to ensure self-consistency in the assigned concentrations, and on laboratory assays of concrete samples from each model to provide traceability to the New Brunswick Laboratory (NBL) standards. 13 references, 7 figures, 17 tables.

  4. GENERAL ASSIGNMENT

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    GENERAL ASSIGNMENT KNOW ALL MEN BY THESE PRESENTS, that ___________________________________, a corporation organized and existing under the laws of the State of ________________________, with its principal place of business at ___________________________________, ___________________________________ has been engaged in performing work under Award Number DE-__________________________with the UNITED STATES OF AMERICA (hereinafter called the "Government"), represented by the UNITED STATES

  5. Intergovernmental Personnel Act Assignments

    Directives, Delegations, and Other Requirements [Office of Management (MA)]

    2000-08-24

    This Manual implements provisions of the Intergovernmental Personnel Act (IPA) within the Department of Energy (DOE) and establishes requirements, responsibilities, and authority for effecting assignments under the Act. Does not cancel other directives.

  6. Handbook on Overseas Assignments

    Office of Energy Efficiency and Renewable Energy (EERE)

    This handbook covers all types of Federal employment overseas, including details, both within DOE as well as to other agencies; transfers to approved international organizations; assignments to permanent DOE positions; cost-free experts; and personal services agreements (PSAs). This handbook contains information, guidance, sample service agreements, and related documentation that are to be used to implement the departments directives.

  7. SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Evaluation

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    of Formal Training | Department of Energy Evaluation of Formal Training SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Evaluation of Formal Training Form is used to evaluate formal training courses in the SES program. SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Evaluation of Formal Training (163.2 KB) More Documents & Publications SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Candidate Developmental Assignment Evaluation SENIOR

  8. Program Assignments | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Services » Procurement Services » Program Assignments Program Assignments Office of Headquarters Procurement Services (MA-64) Program Assignments Mark C. Brady, Director,(202) 287-1389 Patricia Davies, Deputy Director, (202) 586-8975 CORPORATE SERVICES OFFICE - Anthony E. Cicala, Director, MA-64.1, (202) 586-7637 Strategic Initiatives Coordinator Competition Advocate Contracting Activity Task/Delivery Order Ombudsman Policy Flashes Independent Review Deborah Black - (202) 287-1416 Balanced

  9. Unclassified Foreign Visits and Assignments

    Directives, Delegations, and Other Requirements [Office of Management (MA)]

    2004-06-18

    To define a program for unclassified foreign national access to Department of Energy sites, information, and technologies. This Order cancels DOE P 142.1, Unclassified Foreign Visits and Assignments, dated 7-14-99; DOE N 142.1, Unclassified Foreign Visits and Assignments, dated 7-14-99; Secretarial Memorandum Unclassified Foreign Visits and Assignments, dated 7-14-99; Memorandum from Francis S. Blake, Departmental Use of Foreign Access Central Tracking System, dated 11-05-01; Memorandum from Kyle E. McSlarrow, Interim Guidance for Implementation of the Department's Unclassified Foreign Visits and Assignments Program, dated 12-17-02; and Secretarial Memorandum, Policy Exclusion for Unclassified Foreign National's Access to Department of Energy Facilities in Urgent or Emergency Medical Situations, dated 4-10-01. Cancels: DOE P 142.1 and DOE N 142.1

  10. Unclassified Foreign Visits and Assignments

    Directives, Delegations, and Other Requirements [Office of Management (MA)]

    1999-07-14

    To provide interim Department of Energy (DOE) requirements and responsibilities for unclassified visits and assignment by foreign nationals to DOE facilities for unclassified activities. This Notice supplements DOE P 142.1 dated 7-14-99, which sets overall Departmental policy on unclassified foreign visits and assignments. It is a complement to existing counterintelligence and security orders and policies. DOE N 251.53, dated 05/14/03, extends this directive until canceled. Cancels: DOE 1240.2B

  11. Unclassified Foreign Visits and Assignments

    Directives, Delegations, and Other Requirements [Office of Management (MA)]

    1999-07-14

    International cooperation and collaboration is an important element in the effective planning and implementation of many Department of Energy (DOE) programs. DOE and its international partners benefit from the exchange of information that results from a managed process of unclassified visits and assignments by foreign nationals. These visits and assignments must be conducted in a manner consistent with U.S. and DOE national security policies, requirements, and objectives including export control laws and regulations. Canceled by DOE O 142.3. Does not cancel other directives.

  12. Foreign National Visit/Assignment Questionnaire

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Unclassified Foreign National Visits & Assignments Questionnaire Welcome to Department of Energy, Headquarters We are looking forward to your visit or assignment with us. In ...

  13. Unclassified Foreign National Visits & Assignments Questionnaire |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Services » Calibration Facilities » Unclassified Foreign National Visits & Assignments Questionnaire Unclassified Foreign National Visits & Assignments Questionnaire Visitors who are foreign nationals must complete and submit the Unclassified Foreign National Visits & Assignments Questionnaire 30 days before accessing facilities. Unclassified Foreign National Visits & Assignments Questionnaire (192.5 KB) More Documents & Publications HQ FNVA

  14. Foreign National Visit/Assignment Questionnaire

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Information (PII) Company Proprietary Information ... areas are to be visited) Property Protection Area with ... and Assignments 47 Is an Export Control License Required? ...

  15. Preparing for Project Implementation Assigning Accountability...

    Energy.gov [DOE] (indexed site)

    Assigning Accountability for Each Project (April 14, 2010) (598.01 KB) More Documents & Publications Preparing for Project Implementation after an Energy Assessment

  16. JOBAID-LAUNCHING AND COMPLETING ASSIGNED SURVEY

    Energy.gov [DOE]

    The purpose of this job aid is to guide users through the step-by-step process of launching and completing assigned surverys.

  17. Continuous Learning Points Credit Assignment Table | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    PDF icon Microsoft Word - CLPCreditAssignmentTable More Documents & Publications PMCDP Curriculum Learning Map Microsoft Word - AL2006-07.doc PMCDP Certification and Equivalency ...

  18. Organizations' Assignment of Responsibility - DOE Directives,

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Delegations, and Requirements Organizations' Assignment of Responsibility Current By Functional Area By Position Designations Assignments Rescinded by Diane Johnson More filters Less filters Filters applied Δ Hide filters ∇ Show filters (0) [X] Remove all Issue Date Start date End date ffe8aa65e5ad705f837fe439ace37780

  19. Help:Assigning permissions | Open Energy Information

    OpenEI (Open Energy Information) [EERE & EIA]

    search "Assigning permissions" means granting users extra rights within the wiki software (or revoking these rights). This is done by going to the Special:UserRights page, and...

  20. JOBAID-SELF ASSIGNING COURSES (ITEMS)

    Energy.gov [DOE]

    In this jobaid you will learn to use the Course Catalog, Browse Catalog, Recommended Items, Locate and Self-Assign Items (Courses) Using the Search Catalog features, Narrow Course Searches using...

  1. Unclassified Foreign National Visits & Assignments Questionnaire

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Unclassified Foreign National Visits & Assignments Questionnaire |Welcome to U.S. Department of Energy Office of Legacy Management! We are looking forward to your visit or assignment with us. In order to comply with our security requirements and ensure that your time with the Department of Energy goes smoothly we need to obtain some information from you prior to your arrival. Please take a few minutes to provide the information requested below for each member of your party that is not a U.S.

  2. Unclassified Foreign Visits and Assignments Program

    Directives, Delegations, and Other Requirements [Office of Management (MA)]

    2004-06-18

    The order defines a program for unclassified foreign national access to Department of Energy sites, information, and technologies. The page change streamlines the HQs Management Panel review process to include reviews by HSS, IN, and a representative of the cognizant under secretary for access requests involving foreign nationals. Cancels Secretarial Memorandum, Unclassified Foreign Visits and Assignments, dated 7-14-99; Memorandum from Francis S. Blake, Departmental Use of Foreign Access Central Tracking System, dated 11-05-01; Memorandum from Kyle E. McSlarrow, Interim Guidance for Implementation of the Department's Unclassified Foreign Visits and Assignments Program, dated 12-17-02; and Secretarial Memorandum, Policy Exclusion for Unclassified Foreign National's Access to Department of Energy Facilities in Urgent or Emergency Medical Situations, dated 4-10-01. Cancels: DOE P 142.1 and DOE N 142.1

  3. NREL Researcher on Assignment in South Africa

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    on Assignment in South Africa For more information contact: e:mail: Public Affairs Golden, Colo., Oct. 20, 1997 -- A policy analyst with the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) is headed to South Africa for eight months of high-level economic research on the South African electricity supply industry. Principal Analyst Paul Galen in NREL's Center for Energy Analysis and Applications will be a visiting researcher with the South African Minerals and Energy

  4. Unclassified Foreign National Visits and Assignments

    Energy.gov [DOE]

    Attached for your information is a March 9,201 0 Memorandum from the Deputy Secretary relaxing certain check and approval requirements relating to visits and assignments of foreign nationals to DOE facilities and National Laboratories, including National Nuclear Security Administration sites. This is part of an ongoing review of DOE Order 142.3. Please furnish a copy to affected contractors pending revision of the Order and its associated Contractor Requirements Document.

  5. Project Registration Number Assignments (Active) | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Active) Project Registration Number Assignments (Active) As of: May 2016 Provides a table of Project Registration Number Assignments (Active) Project Registration Number Assignment (Active) (511.76 KB) More Documents & Publications All Active DOE Technical Standards Document Project Registration Number Assignments (Completed

  6. Project Registration Number Assignments (Completed) | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Completed) Project Registration Number Assignments (Completed) As of: May 2016 Provides a table of Project Registration Number Assignments (Completed) Project Registration Number Assignments (Completed) (406.85 KB) More Documents & Publications All Active DOE Technical Standards Document Project Registration Number Assignments (Active

  7. Artificial leaf jumps developmental hurdle

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    developmental hurdle 18 Feb 2014 by Jenny Green: In a recent early online edition of Nature Chemistry, ASU scientists, along with colleagues at Argonne National Laboratory, have...

  8. Parameter Assignments for Spectral Gamma-Ray Borehole Calibration Models

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    (April 1984) | Department of Energy Parameter Assignments for Spectral Gamma-Ray Borehole Calibration Models (April 1984) Parameter Assignments for Spectral Gamma-Ray Borehole Calibration Models (April 1984) Parameter Assignments for Spectral Gamma-Ray Borehole Calibration Models (April 1984) Parameter Assignments for Spectral Gamma-Ray Borehole Calibration Models (April 1984) (3.25 MB) More Documents & Publications Grade Assignments for Models Used for Calibration of Gross-Count

  9. Calibration Pad Assignments for Spectral Gamma (November 1985) | Department

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    of Energy Pad Assignments for Spectral Gamma (November 1985) Calibration Pad Assignments for Spectral Gamma (November 1985) Calibration Pad Assignments for Spectral Gamma (November 1985) Calibration Pad Assignments for Spectral Gamma (November 1985) (5.3 MB) More Documents & Publications Parameter Assignments for Spectral Gamma-Ray Borehole Calibration Models (April 1984) Field Calibration Facilities for Environmental Measurement of Radium, Thorium, and Potassium (October 2013) Grade

  10. 3210T3 Risk Code Assignment;

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    210 Appendix T3 Risk Code Assignment 1.0 Purpose Identification of work hazards and understanding their risks is an essential part of Jefferson Lab's work process as defined in ES&H Manual Chapter 3210 Appendix T1 Work Planning, Control, and Authorization Procedure. The purpose of this document is to demonstrate the accepted method for determining the Risk Code for task steps identified while completing Task Hazard Analysis (THA) Worksheet. 2.0 Scope This appendix describes the procedure for

  11. Foreign Visits & Assignments Guidelines | The Ames Laboratory

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Foreign Visits & Assignments Guidelines Foreign Visits and Assignments Requests (473's) and Specific Security Plans Please use the following links to reach Form 473, the Foreign Visits and Assignments Request Form, as well as the Ames Laboratory Specific Security Plan Form. Form 473 Foreign Visits and Assignments Request Form Specific Security Plan Program Overview. The USDOE considers hosting foreign visitors a critical responsibility. This is especially true when the foreign national is

  12. Chief of Nuclear Safety (CNS) Staff Assignments & Expertise ...

    Energy.gov [DOE] (indexed site)

    Chief of Nuclear Safety (CNS) Staff Assignments & Expertise CNS staff maintains adequate technical proficiency, including the timely completion of Senior Technical Safety Manager...

  13. FOAM (Functional Ontology Assignments for Metagenomes): A Hidden...

    Office of Scientific and Technical Information (OSTI)

    Ontology Assignments for Metagenomes): A Hidden Markov Model (HMM) database with environmental focus Citation Details In-Document Search Title: FOAM (Functional Ontology...

  14. Acquisition Letter on Contractor Domestic Extended Personnel Assignments

    Energy.gov [DOE]

    The attached Acquisition Letter has been issued to provide guidance on the Department's policy governing reimbursement of costs associated with contractor domestic extended personnel assignments.

  15. Recognizing and Assigning ESPC Risks and Responsibilities Using...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Using the Risk, Responsibility, and Performance Matrix Recognizing and Assigning ESPC Risks and Responsibilities Using the Risk, Responsibility, and Performance Matrix ...

  16. Measuring the maturity of a technology : guidance on assigning...

    Office of Scientific and Technical Information (OSTI)

    Technical Report: Measuring the maturity of a technology : guidance on assigning a TRL. ... for supplier-customer interactions at a very early stage in technology development. ...

  17. Evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Savings Portfolio (122013) Energy Smart Grocer Impact Evaluation (102013) Energy Smart Industrial - Energy Management Pilot Impact Evaluation (22013) Clark PUD Home...

  18. A Pareto-efficient combustion framework with submodel assignment for

    Office of Scientific and Technical Information (OSTI)

    predicting complex flame configurations (Journal Article) | SciTech Connect Journal Article: A Pareto-efficient combustion framework with submodel assignment for predicting complex flame configurations Citation Details In-Document Search This content will become publicly available on November 4, 2017 Title: A Pareto-efficient combustion framework with submodel assignment for predicting complex flame configurations Authors: Wu, Hao Search SciTech Connect for author "Wu, Hao" Search

  19. NNSA authorizes mission assignment transfer to Kansas City Plant | National

    National Nuclear Security Administration (NNSA)

    Nuclear Security Administration | (NNSA) authorizes mission assignment transfer to Kansas City Plant Wednesday, June 25, 2014 - 1:05pm To improve efficiency across the nuclear security enterprise, NNSA recently transferred the mission assignment of several product families from Sandia National Laboratories to the Kansas City Plant. The mission reassignment better aligns responsibilities with each site's core competencies and will leverage Kansas City's Supply Chain Management systems and

  20. Statistical methods of spin assignment in compound nuclear reactions

    SciTech Connect

    Mach, H.; Johns, M.W.

    1985-01-15

    Spin assignment to nuclear levels can be obtained from standard in-beam gamma-ray spectroscopy techniques and in the case of compound nuclear reactions can be complemented by statistical methods. These are based on a correlation pattern between level spin and gamma-ray intensities feeding low-lying levels. Three types of intensity and level spin correlations are found suitable for spin assignment: shapes of the excitation functions, ratio of intensity at two beam energies or populated in two different reactions, and feeding distributions. Various empirical attempts are examined and the range of applicability of these methods as well as the limitations associated with them are given.

  1. Electric Utility Company Assigned to a Zip Code? | OpenEI Community

    OpenEI (Open Energy Information) [EERE & EIA]

    Electric Utility Company Assigned to a Zip Code? Home I have found an error in the utility company assigned to a zip code. I am not sure if the "assigned" utility company covers...

  2. Method for assigning sites to projected generic nuclear power plants

    SciTech Connect

    Holter, G.M.; Purcell, W.L.; Shutz, M.E.; Young, J.R.

    1986-07-01

    Pacific Northwest Laboratory developed a method for forecasting potential locations and startup sequences of nuclear power plants that will be required in the future but have not yet been specifically identified by electric utilities. Use of the method results in numerical ratings for potential nuclear power plant sites located in each of the 10 federal energy regions. The rating for each potential site is obtained from numerical factors assigned to each of 5 primary siting characteristics: (1) cooling water availability, (2) site land area, (3) power transmission land area, (4) proximity to metropolitan areas, and (5) utility plans for the site. The sequence of plant startups in each federal energy region is obtained by use of the numerical ratings and the forecasts of generic nuclear power plant startups obtained from the EIA Middle Case electricity forecast. Sites are assigned to generic plants in chronological order according to startup date.

  3. 2210R1 ES&H Staff Assignments

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    210 Appendix R1 Staff Assigned to ES&H Activities 1.0 Purpose This appendix provides information for current Environmental, Safety and Health (ES&H) related staff positions at Jefferson Lab. Other positions of responsibility are outlined on the various Division & Department's Organization Charts. * Section 2.0 - Contact Information for Hazard Issues * Section 3.0 - Contact Information for Responsible Positions * Section 4.0 - Councils and Committees * Section 5.0 - Division Safety

  4. DOE F 360.3 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    3 DOE F 360.3 Form is used to provide basic information about the SES candidate, qualifications, and the assignment. SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Developmental Assignment Opportunity (132.31 KB) More Documents & Publications SESCDP Supervisor's Evaluation of Candidate's Performance During Developmental Assignment SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Candidate Developmental Assignment Evaluation SENIOR EXECUTIVE SERVICE CANDIDATE

  5. SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Candidate

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Developmental Assignment Evaluation | Department of Energy Candidate Developmental Assignment Evaluation SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Candidate Developmental Assignment Evaluation Form allows ESE candidates to evaluate assignments in terms of the executive core qualities the assignment was intended to meet, how well it met expectations and provided a learning experience, what prior knowledge or experience might have been adventageous, whether to recommend

  6. Automated Pre-processing for NMR Assignments with Reduced Tedium

    Energy Science and Technology Software Center

    2004-05-11

    An important rate-limiting step in the reasonance asignment process is accurate identification of resonance peaks in MNR spectra. NMR spectra are noisy. Hence, automatic peak-picking programs must navigate between the Scylla of reliable but incomplete picking, and the Charybdis of noisy but complete picking. Each of these extremes complicates the assignment process: incomplete peak-picking results in the loss of essential connectivities, while noisy picking conceals the true connectivities under a combinatiorial explosion of false positives.more » Intermediate processing can simplify the assignment process by preferentially removing false peaks from noisy peak lists. This is accomplished by requiring consensus between multiple NMR experiments, exploiting a priori information about NMR spectra, and drawing on empirical statistical distributions of chemical shift extracted from the BioMagResBank. Experienced NMR practitioners currently apply many of these techniques "by hand", which is tedious, and may appear arbitrary to the novice. To increase efficiency, we have created a systematic and automated approach to this process, known as APART. Automated pre-processing has three main advantages: reduced tedium, standardization, and pedagogy. In the hands of experienced spectroscopists, the main advantage is reduced tedium (a rapid increase in the ratio of true peaks to false peaks with minimal effort). When a project is passed from hand to hand, the main advantage is standardization. APART automatically documents the peak filtering process by archiving its original recommendations, the accompanying justifications, and whether a user accepted or overrode a given filtering recommendation. In the hands of a novice, this tool can reduce the stumbling block of learning to differentiate between real peaks and noise, by providing real-time examples of how such decisions are made.« less

  7. Assigning Seismic Design Category to Large Reactors: A Case Study of the ATR

    Energy.gov [DOE]

    Assigning Seismic Design Category to Large Reactors: A Case Study of the ATR Stuart Jensen October 21, 2014

  8. New models and molecular markers in evaluation of developmental toxicity

    SciTech Connect

    Huuskonen, Hannele . E-mail: hannele.huuskonen@sttv.fi

    2005-09-01

    Mammalian and non-mammalian embryos and embryonic stem cells may be used as models in mechanistic studies and in testing embryotoxicity of compounds. In addition to conventional culture methods, genetic modifications and use of molecular markers offer significant advantages in mechanistic studies as well as in developing new test methods for embryotoxicity. Zebrafish model has been used for a long time and at present several applications are available. It is an easy vertebral non-mammalian model, whose genome is largely known and several genetic modifications are easily constructed to study gene expression or knocked down genes. Fluorescent marker proteins can be used also in zebrafish to indicate gene activation in transgenic models. Chemical genetics approach has been developed using zebrafish model. This is a new approach to screen small molecules that regulate signaling pathways. Embryonic stem cells have been used in mechanistic studies and mouse embryonic stem cell test has been validated to study embryotoxicity in vitro. This method has been improved using quantitative measurements of molecular endpoints by real-time RT-PCR or fluorescent activated cell sorting methods (FACS). Methods facilitating differentiation to several different cell types are available. We have studied preimplantation mouse embryos as a possible model for in vitro testing. In this method, superovulated and in vivo fertilized preimplantation embryos were collected at morula stage and cultured up to blastocysts. The mouse preimplantation culture test was improved by quantitative gene expression measurement using two-step real-time RT-PCR methods. New endpoints improve the tests of in vitro embryotoxicity because subjective assessments are replaced by objective measurements. In addition, automation is possible and less time is needed for analysis. Thus, high throughput screening will come possible to test large numbers of compounds.

  9. Term Assignments of Contractors to the Washington D.C. Area.

    Office of Energy Efficiency and Renewable Energy (EERE)

    On July 2, 2013 the DOE Office of the Inspector General issued Audit Report Number 0890 entitled, "Follow-up Audit on Term Assignments of Contractor Employees." The audit was conducted as a follow-up of the FY 2005 audit of "Management of Facility Contractors Assigned to the Washington D.C. area DOE/IG 0710." The earlier report found instances where assignment justifications were insufficient, costs appeared excessive and allowances inconsistent. The follow-up audit recognized improved management of assignments but noted assignment justifications and cost management could be improved. The report recommended DOE determine prior year actual costs to assist in calculating the estimated costs for the upcoming year of multi-year assignments and ensure assignment records in the Departmental Management and Tracking System (DMATS) are accurate.

  10. Assignments of the Raman modes of monoclinic erbium oxide

    SciTech Connect

    Yan, D.; Wu, P. Zhang, S. P.; Liang, L.; Yang, F.; Pei, Y. L.; Chen, S.

    2013-11-21

    As a heavy rare earth oxide, erbium oxide (Er{sub 2}O{sub 3}) has many attractive properties. Monoclinic Er{sub 2}O{sub 3} has useful properties not found in stable cubic Er{sub 2}O{sub 3}, such as unique optical properties and high radiation damage tolerance. In this study, cubic Er{sub 2}O{sub 3} coating and Er{sub 2}O{sub 3} coating with mixed phases were prepared. The Raman scattering spectra of these coatings were investigated by using a confocal micro-Raman spectrometer equipped with 325, 473, 514, 532, 633, and 784 nm lasers. A total of 17 first-order Raman modes of monoclinic Er{sub 2}O{sub 3} were identified and assigned. The modes at 83, 112, 152, 170, 278, 290, 409, 446, 478, 521, 603, and 622 cm{sup −1} are of A{sub g} symmetry, whereas modes at 71, 98, 333, 409, 446, and 468 cm{sup −1} are of B{sub g} symmetry. This research provides basic data necessary for the characterization of monoclinic Er{sub 2}O{sub 3} by Raman spectroscopy.

  11. Chief of Nuclear Safety (CNS) Staff Assignments & Expertise | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Energy Chief of Nuclear Safety (CNS) Staff Assignments & Expertise Chief of Nuclear Safety (CNS) Staff Assignments & Expertise Chief of Nuclear Safety (CNS) Staff Assignments & Expertise CNS staff maintains adequate technical proficiency, including the timely completion of Senior Technical Safety Manager (STSM) qualification. Further, CNS staff periodically review and assess whether EM is maintaining adequate numbers of technically competent personnel necessary to fulfill its

  12. Recognizing and Assigning ESPC Risks and Responsibilities Using the Risk, Responsibility, and Performance Matrix

    Energy.gov [DOE]

    Document offers guidance on how to recognize and assign energy savings performance contract (ESPC) risks and responsibilities using the risk, responsibility, and performance matrix, also known as RRPM.

  13. Calibration Model Assignments expressed as U3O8, Summary Table ES-1 |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy Model Assignments expressed as U3O8, Summary Table ES-1 Calibration Model Assignments expressed as U3O8, Summary Table ES-1 Calibration Model Assignments expressed as U3O8, Summary Table ES-1 Calibration Model Assignments expressed as U3O8, Summary Table ES-1 (25.9 KB) More Documents & Publications Field Calibration Facilities for Environmental Measurement of Radium, Thorium, and Potassium (October 2013) Offshore Wind Market and Economic Analysis Report 2013 Natural

  14. Audit Report - Follow-up Audit on Term Assignments of Contractor...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    when compared to other means of acquiring the necessary knowledge and experience. Our 2005 report on Management of Facility Contractors Assigned to the Washington, DC Area ...

  15. Grade Assignments for Models Used for Calibration of Gross-Count Gamma-Ray

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Logging Systems (December 1983) | Department of Energy Grade Assignments for Models Used for Calibration of Gross-Count Gamma-Ray Logging Systems (December 1983) Grade Assignments for Models Used for Calibration of Gross-Count Gamma-Ray Logging Systems (December 1983) Grade Assignments for Models Used for Calibration of Gross-Count Gamma-Ray Logging Systems (December 1983) Grade Assignments for Models Used for Calibration of Gross-Count Gamma-Ray Logging Systems (December 1983) (2.28 MB)

  16. Hydroxylated PBDEs induce developmental arrest in zebrafish

    SciTech Connect

    Usenko, Crystal Y. Hopkins, David C.; Trumble, Stephen J. Bruce, Erica D.

    2012-07-01

    The ubiquitous spread of polybrominated diphenyl ethers (PBDEs) has led to concerns regarding the metabolites of these congeners, in particular hydroxylated PBDEs. There are limited studies regarding the biological interactions of these chemicals, yet there is some concern they may be more toxic than their parent compounds. In this study three hydroxylated PBDEs were assessed for toxicity in embryonic zebrafish: 3-OH-BDE 47, 5-OH-BDE 47, and 6-OH-BDE 47. All three congeners induced developmental arrest in a concentration-dependent manner; however, 6-OH-BDE 47 induced adverse effects at lower concentrations than the other congeners. Furthermore, all three induced cell death; however apoptosis was not observed. In short-term exposures (24–28 hours post fertilization), all hydroxylated PBDEs generated oxidative stress in the region corresponding to the cell death at 5 and 10 ppm. To further investigate the short-term effects that may be responsible for the developmental arrest observed in this study, gene regulation was assessed for embryos exposed to 0.625 ppm 6-OH-BDE 47 from 24 to 28 hpf. Genes involved in stress response, thyroid hormone regulation, and neurodevelopment were significantly upregulated compared to controls; however, genes related to oxidative stress were either unaffected or downregulated. This study suggests that hydroxylated PBDEs disrupt development, and may induce oxidative stress and potentially disrupt the cholinergic system and thyroid hormone homeostasis. -- Highlights: ► OH-PBDEs induce developmental arrest in a concentration-dependent manner. ► Hydroxyl group location influences biological interaction. ► OH-PBDEs induce oxidative stress. ► Thyroid hormone gene regulation was disrupted following exposure. ► To our knowledge, this is the first whole organism study of OH-PBDE toxicity.

  17. Developmental Control of Lignification in Stems of Lowland Switchgrass...

    Office of Scientific and Technical Information (OSTI)

    Developmental Control of Lignification in Stems of Lowland Switchgrass Variety Alamo and ... Sponsoring Org: USDOE Office of Science (SC), Biological and Environmental Research (BER) ...

  18. Comparative developmental toxicity of environmentally relevant oxygenated PAHs

    SciTech Connect

    Knecht, Andrea L.; Goodale, Britton C.; Truong, Lisa; Simonich, Michael T.; Swanson, Annika J.; Matzke, Melissa M.; Anderson, Kim A.; Waters, Katrina M.; Tanguay, Robert L.

    2013-09-01

    Oxygenated polycyclic aromatic hydrocarbons (OPAHs) are byproducts of combustion and photo-oxidation of parent PAHs. OPAHs are widely present in the environment and pose an unknown hazard to human health. The developing zebrafish was used to evaluate a structurally diverse set of 38 OPAHs for malformation induction, gene expression changes and mitochondrial function. Zebrafish embryos were exposed from 6 to 120 h post fertilization (hpf) to a dilution series of 38 different OPAHs and evaluated for 22 developmental endpoints. AHR activation was determined via CYP1A immunohistochemistry. Phenanthrenequinone (9,10-PHEQ), 1,9-benz-10-anthrone (BEZO), xanthone (XAN), benz(a)anthracene-7,12-dione (7,12-B[a]AQ), and 9,10-anthraquinone (9,10-ANTQ) were evaluated for transcriptional responses at 48 hpf, prior to the onset of malformations. qRT-PCR was conducted for a number of oxidative stress genes, including the glutathione transferase(gst), glutathione peroxidase(gpx), and superoxide dismutase(sod) families. Bioenergetics was assayed to measure in vivo oxidative stress and mitochondrial function in 26 hpf embryos exposed to OPAHs. Hierarchical clustering of the structure-activity outcomes indicated that the most toxic of the OPAHs contained adjacent diones on 6-carbon moieties or terminal, para-diones on multi-ring structures. 5-carbon moieties with adjacent diones were among the least toxic OPAHs while the toxicity of multi-ring structures with more centralized para-diones varied considerably. 9,10-PHEQ, BEZO, 7,12-B[a]AQ, and XAN exposures increased expression of several oxidative stress related genes and decreased oxygen consumption rate (OCR), a measurement of mitochondrial respiration. Comprehensive in vivo characterization of 38 structurally diverse OPAHs indicated differential AHR dependency and a prominent role for oxidative stress in the toxicity mechanisms. - Highlights: • OPAHs are byproducts of combustion present in the environment. • OPAHs pose a largely

  19. User 'To Do' List after Beam Time is Assigned | Linac Coherent...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    SSRL hosts will be assigned and visits will be coordinated with DOE through the Foreign Access Central Tracking System (FACTS). Advance approval is required for users who were born ...

  20. A path towards uncertainty assignment in an operational cloud-phase

    Office of Scientific and Technical Information (OSTI)

    algorithm from ARM vertically pointing active sensors (Journal Article) | DOE PAGES Published Article: A path towards uncertainty assignment in an operational cloud-phase algorithm from ARM vertically pointing active sensors Title: A path towards uncertainty assignment in an operational cloud-phase algorithm from ARM vertically pointing active sensors Knowledge of cloud phase (liquid, ice, mixed, etc.) is necessary to describe the radiative impact of clouds and their lifetimes, but is a

  1. Unclassified Foreign National Visits and Assignments at Oak Ridge National Laboratory

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Unclassified Foreign National Visits and Assignments at Oak Ridge National Laboratory INS-O-13-05 September 2013 Department of Energy Washington, DC 20585 September 16, 2013 MEMORANDUM FOR THE MANAGER, OAK RIDGE NATIONAL LABORATORY SITE OFFICE FROM: Sandra D. Bruce Assistant Inspector General for Inspections Office of Inspector General SUBJECT: INFORMATION: Inspection Report on "Unclassified Foreign National Visits and Assignments at Oak Ridge National Laboratory" BACKGROUND In support

  2. METHODOLOGY AND CALCULATIONS FOR THE ASSIGNMENT OF WASTE GROUPS FOR THE LARGE UNDERGROUND WASTE STORAGE TANKS AT THE HANFORD SITE

    SciTech Connect

    FOWLER KD

    2007-12-27

    material and release gas and are assigned to waste group B. These tanks are considered to represent a potential induced flammable gas release hazard, but no spontaneous buoyant displacement flammable gas release hazard. Tanks that are not waste group C tanks and have an energy ratio {ge} 3.0, but that pass the third criterion (buoyancy ratio < 1.0, see below) are also assigned to waste group B. Even though the designation as a waste group B (or A) tank identifies the potential for an induced flammable gas release hazard, the hazard only exists for specific operations that can release the retained gas in the tank at a rate and quantity that results in reaching 100% of the lower flammability limit in the tank headspace. The identification and evaluation of tank farm operations that could cause an induced flammable gas release hazard in a waste group B (or A) tank are included in other documents. The third criterion is the buoyancy ratio. This criterion addresses tanks that are not waste group C double-shell tanks and have an energy ratio {ge} 3.0. For these double-shell tanks, the buoyancy ratio considers whether the saturated solids can retain sufficient gas to exceed neutral buoyancy relative to the supernatant layer and therefore have buoyant displacement gas release events. If the buoyancy ratio is {ge} 1.0, that double-shell tank is assigned to waste group A. These tanks are considered to have a potential spontaneous buoyant displacement flammable gas release hazard in addition to a potential induced flammable gas release hazard.

  3. METHODOLOGY AND CALCULATIONS FOR THE ASSIGNMENT OF WASTE GROUPS FOR THE LARGE UNDERGROUND WASTE STORAGE TANKS AT THE HANFORD SITE

    SciTech Connect

    WEBER RA

    2009-01-16

    group B (or A) tank identifies the potential for an induced flammable gas release hazard, the hazard only exists for specific operations that can release the retained gas in the tank at a rate and quantity that results in reaching 100% of the lower flammability limit in the tank headspace. The identification and evaluation of tank farm operations that could cause an induced flammable gas release hazard in a waste group B (or A) tank are included in other documents. The third criterion is the buoyancy ratio. This criterion addresses tanks that are not waste group C double-shell tanks and have an energy ratio {ge} 3.0. For these double-shell tanks, the buoyancy ratio considers whether the saturated solids can retain sufficient gas to exceed neutral buoyancy relative to the supernatant layer and therefore have buoyant displacement gas release events. If the buoyancy ratio is {ge} 1.0, that double-shell tank is assigned to waste group A. These tanks are considered to have a potential spontaneous buoyant displacement flammable gas release hazard in addition to a potential induced flammable gas release hazard. This document categorizes each of the large waste storage tanks into one of several categories based on each tank's waste characteristics. These waste group assignments reflect a tank's propensity to retain a significant volume of flammable gases and the potential of the waste to release retained gas by a buoyant displacement event. Revision 8 is the annual update of the calculations of the flammable gas Waste Groups for DSTs and SSTs.

  4. Method and system for assigning a confidence metric for automated determination of optic disc location

    DOEpatents

    Karnowski, Thomas P.; Tobin, Jr., Kenneth W.; Muthusamy Govindasamy, Vijaya Priya; Chaum, Edward

    2012-07-10

    A method for assigning a confidence metric for automated determination of optic disc location that includes analyzing a retinal image and determining at least two sets of coordinates locating an optic disc in the retinal image. The sets of coordinates can be determined using first and second image analysis techniques that are different from one another. An accuracy parameter can be calculated and compared to a primary risk cut-off value. A high confidence level can be assigned to the retinal image if the accuracy parameter is less than the primary risk cut-off value and a low confidence level can be assigned to the retinal image if the accuracy parameter is greater than the primary risk cut-off value. The primary risk cut-off value being selected to represent an acceptable risk of misdiagnosis of a disease having retinal manifestations by the automated technique.

  5. Taxonomic and developmental aspects of radiosensitivity

    SciTech Connect

    Harrison, F.L.; Anderson, S.L.

    1996-11-01

    Considerable information is available on the effects of radioactivity on adult and early life stages of organisms. The preponderance of data is on mortality after a single irradiation with relatively high doses. Unfortunately, because experiments were carried out under different conditions and for different time periods, the validity of comparing the results from different laxonomic groups is questionable. In general, the conclusions are that there is a relationship (1) between radioresistance to high doses of acute radiation and taxonomy of the organism, primitive forms being more radioresistant than complex vertebrates and (2) between radiosensitivity and developmental stage, early life stages being more sensitive than later stages. The first conclusion may be related to the capability of the organism to repopulate cells and to differentiate and redifferentiate them; the second to the rate of cellular division and to the degree of differentiation. In question, however, is the relevance of the responses from high levels of acute radiation to that of the responses to long-term exposure to low levels of radiation, which are ecologically of more interest. Data from studies of the effects of acute and chronic exposure on development of gametes and zygotes indicate that, for some fishes and invertebrates, responses at the cellular and molecular levels show effect levels comparable to those observed in some mammals. Acute doses between 0,05 and 0.5Cy and dose rates between 0.02 to 0.2mCy/h appear to define critical ranges in which detrimental effects on fertility are first observed in a variety of radiosensitive organisms. To better understand inherent radiosensitivity, we need more information on the ability of cells to repopulate and differentiate and to prevent or repair damage to biological critical molecules, such as DNA, because these factors may alter significantly organisms` responses to radiation.

  6. Homologous recombination and non-homologous end-joining repair pathways in bovine embryos with different developmental competence

    SciTech Connect

    Henrique Barreta, Marcos; Laboratorio de Biotecnologia e Reproducao Animal-BioRep, Universidade Federal de Santa Maria, Santa Maria, RS ; Garziera Gasperin, Bernardo; Braga Rissi, Vitor; Cesaro, Matheus Pedrotti de; Ferreira, Rogerio; Oliveira, Joao Francisco de; Goncalves, Paulo Bayard Dias; Bordignon, Vilceu

    2012-10-01

    This study investigated the expression of genes controlling homologous recombination (HR), and non-homologous end-joining (NHEJ) DNA-repair pathways in bovine embryos of different developmental potential. It also evaluated whether bovine embryos can respond to DNA double-strand breaks (DSBs) induced with ultraviolet irradiation by regulating expression of genes involved in HR and NHEJ repair pathways. Embryos with high, intermediate or low developmental competence were selected based on the cleavage time after in vitro insemination and were removed from in vitro culture before (36 h), during (72 h) and after (96 h) the expected period of embryonic genome activation. All studied genes were expressed before, during and after the genome activation period regardless the developmental competence of the embryos. Higher mRNA expression of 53BP1 and RAD52 was found before genome activation in embryos with low developmental competence. Expression of 53BP1, RAD51 and KU70 was downregulated at 72 h and upregulated at 168 h post-insemination in response to DSBs induced by ultraviolet irradiation. In conclusion, important genes controlling HR and NHEJ DNA-repair pathways are expressed in bovine embryos, however genes participating in these pathways are only regulated after the period of embryo genome activation in response to ultraviolet-induced DSBs.

  7. The developmental transcriptome of Drosophila melanogaster

    SciTech Connect

    University of Connecticut; Graveley, Brenton R.; Brooks, Angela N.; Carlson, Joseph W.; Duff, Michael O.; Landolin, Jane M.; Yang, Li; Artieri, Carlo G.; van Baren, Marijke J.; Boley, Nathan; Booth, Benjamin W.; Brown, James B.; Cherbas, Lucy; Davis, Carrie A.; Dobin, Alex; Li, Renhua; Lin, Wei; Malone, John H.; Mattiuzzo, Nicolas R.; Miller, David; Sturgill, David; Tuch, Brian B.; Zaleski, Chris; Zhang, Dayu; Blanchette, Marco; Dudoit, Sandrine; Eads, Brian; Green, Richard E.; Hammonds, Ann; Jiang, Lichun; Kapranov, Phil; Langton, Laura; Perrimon, Norbert; Sandler, Jeremy E.; Wan, Kenneth H.; Willingham, Aarron; Zhang, Yu; Zou, Yi; Andrews, Justen; Bicke, Peter J.; Brenner, Steven E.; Brent, Michael R.; Cherbas, Peter; Gingeras, Thomas R.; Hoskins, Roger A.; Kaufman, Thomas C.; Oliver, Brian; Celniker, Susan E.

    2010-12-02

    Drosophila melanogaster is one of the most well studied genetic model organisms; nonetheless, its genome still contains unannotated coding and non-coding genes, transcripts, exons and RNA editing sites. Full discovery and annotation are pre-requisites for understanding how the regulation of transcription, splicing and RNA editing directs the development of this complex organism. Here we used RNA-Seq, tiling microarrays and cDNA sequencing to explore the transcriptome in 30 distinct developmental stages. We identified 111,195 new elements, including thousands of genes, coding and non-coding transcripts, exons, splicing and editing events, and inferred protein isoforms that previously eluded discovery using established experimental, prediction and conservation-based approaches. These data substantially expand the number of known transcribed elements in the Drosophila genome and provide a high-resolution view of transcriptome dynamics throughout development. Drosophila melanogaster is an important non-mammalian model system that has had a critical role in basic biological discoveries, such as identifying chromosomes as the carriers of genetic information and uncovering the role of genes in development. Because it shares a substantial genic content with humans, Drosophila is increasingly used as a translational model for human development, homeostasis and disease. High-quality maps are needed for all functional genomic elements. Previous studies demonstrated that a rich collection of genes is deployed during the life cycle of the fly. Although expression profiling using microarrays has revealed the expression of, 13,000 annotated genes, it is difficult to map splice junctions and individual base modifications generated by RNA editing using such approaches. Single-base resolution is essential to define precisely the elements that comprise the Drosophila transcriptome. Estimates of the number of transcript isoforms are less accurate than estimates of the number of genes

  8. Balance Calibration A Method for Assigning a Direct-Reading Uncertainty to an Electronic Balance.

    SciTech Connect

    Mike Stears

    2010-07-01

    Paper Title: Balance Calibration A method for assigning a direct-reading uncertainty to an electronic balance. Intended Audience: Those who calibrate or use electronic balances. Abstract: As a calibration facility, we provide on-site (at the customers location) calibrations of electronic balances for customers within our company. In our experience, most of our customers are not using their balance as a comparator, but simply putting an unknown quantity on the balance and reading the displayed mass value. Manufacturers specifications for balances typically include specifications such as readability, repeatability, linearity, and sensitivity temperature drift, but what does this all mean when the balance user simply reads the displayed mass value and accepts the reading as the true value? This paper discusses a method for assigning a direct-reading uncertainty to a balance based upon the observed calibration data and the environment where the balance is being used. The method requires input from the customer regarding the environment where the balance is used and encourages discussion with the customer regarding sources of uncertainty and possible means for improvement; the calibration process becomes an educational opportunity for the balance user as well as calibration personnel. This paper will cover the uncertainty analysis applied to the calibration weights used for the field calibration of balances; the uncertainty is calculated over the range of environmental conditions typically encountered in the field and the resulting range of air density. The temperature stability in the area of the balance is discussed with the customer and the temperature range over which the balance calibration is valid is decided upon; the decision is based upon the uncertainty needs of the customer and the desired rigor in monitoring by the customer. Once the environmental limitations are decided, the calibration is performed and the measurement data is entered into a custom

  9. Measuring the maturity of a technology : guidance on assigning a TRL.

    SciTech Connect

    Mitchell, John Anthony

    2007-10-01

    This report provides guidance on how to assign a technology readiness level (TRL). The method proposed assists in assigning TRLs through a series of questions that focus on a set of unambiguous maturation metrics. This method is slightly biased towards the environment and approach to technology maturation at Sandia National Laboratories where customers and suppliers are in very close proximity to one another, allowing for supplier-customer interactions at a very early stage in technology development. The hope is that this report can serve as a practical guide to anyone trying to understand the maturity of a specific technology. Risk is reduced in system acquisition by selecting mature technologies for inclusion in system development. TRLs are used to assess the maturity of evolving technologies and therefore become part of an overall risk reduction strategy in system development.

  10. Manual of functions, assignments, and responsibilities for nuclear safety: Revision 2

    SciTech Connect

    Not Available

    1994-10-15

    The FAR Manual is a convenient easy-to-use collection of the functions, assignments, and responsibilities (FARs) of DOE nuclear safety personnel. Current DOE directives, including Orders, Secretary of Energy Notices, and other assorted policy memoranda, are the source of this information and form the basis of the FAR Manual. Today, the majority of FARs for DOE personnel are contained in DOE`s nuclear safety Orders. As these Orders are converted to rules in the Code of Federal Regulations, the FAR Manual will become the sole source for information relating to the functions, assignments, responsibilities of DOE nuclear safety personnel. The FAR Manual identifies DOE directives that relate to nuclear safety and the specific DOE personnel who are responsible for implementing them. The manual includes only FARs that have been extracted from active directives that have been approved in accordance with the procedures contained in DOE Order 1321.1B.

  11. Inhalation developmental toxicology studies: Developmental toxicity of chloroprene vapors in New Zealand white rabbits. Final report

    SciTech Connect

    Mast, T.J.; Evanoff, J.J.; Westerberg, R.B.; Rommereim, R.L.; Weigel, R.J.

    1994-04-01

    Chloroprene, 2-chloro-1,3-butadiene, is a colorless liquid with a pungent ethereal odor that is primarily used as an intermediate in the manufacture of neoprene rubber, and has been used as such since about 1930. This study addressed the potential for chloroprene to cause developmental toxicity in New Zealand white rabbits following gestational exposure to 0, 10, 40, or 175 ppm chloroprene vapors, 6h/dy, 7dy/wk. Each treatment group consisted of 15 artificially inseminated females exposed on 6 through 28 days of gestation (dg). Body weights were obtained throughout the study period, and uterine and fetal body weights were obtained at sacrifice on 29 dg. Implants were enumerated and their status recorded and live fetuses were examined for gross, visceral, skeletal, and soft-tissue craniofacial defects. There were no overt signs of maternal toxicity and the change in maternal body weight over the course of the study was not affected. Exposure of pregnant rabbits to chloroprene vapors on 6-28 dg had no effect on the number of implantation, the mean percent of live pups per litter, or on the incidence of resorptions per litter. The incidence of fetal malformations was not increased by exposure to chloroprene. Results of this study indicate that gestational exposure of New Zealand white rabbits to 10, 40, or 175 ppm chloroprene did not result in observable toxicity to either the dam or the offspring.

  12. Creative solutions for complex developmental testing

    SciTech Connect

    1993-07-01

    Sandia National Laboratories was requested to establish the FAA Aging Aircraft Nondestructive Inspection (NDI) Development and Demonstration Center. The Center is housed in a hangar at the Albuquerque International Airport and owns its own aged transport airplane. The Center`s work encompasses research and development in enhanced structural inspection. The goals of the Center are to: promote NDI technology development and maturation; help transfer new nondevelopment item technology to the hangar floor; validate NDI techniques; assess reliability or probability of detection of NDI processes. An important part of this project will be to make sure that the cost of implementation and operation of any technique is seriously considered and that techniques are usable in the field. Among the initial techniques to be evaluated are: enhanced visual, magneto-optic eddy current; coherent optics; ultrasonics; thermographics; eddy current scanners; experimental modal analysis. This project is a perfect example of how Development Testing draws on its own resources and teams up with others, as necessary, to get the job done. In this case, New Mexico State University and a private company, Science Applications International Corporation, are assisting.

  13. Developmental defects in zebrafish for classification of EGF pathway inhibitors

    SciTech Connect

    Pruvot, Benoist; Curé, Yoann; Djiotsa, Joachim; Voncken, Audrey; Muller, Marc

    2014-01-15

    One of the major challenges when testing drug candidates targeted at a specific pathway in whole animals is the discrimination between specific effects and unwanted, off-target effects. Here we used the zebrafish to define several developmental defects caused by impairment of Egf signaling, a major pathway of interest in tumor biology. We inactivated Egf signaling by genetically blocking Egf expression or using specific inhibitors of the Egf receptor function. We show that the combined occurrence of defects in cartilage formation, disturbance of blood flow in the trunk and a decrease of myelin basic protein expression represent good indicators for impairment of Egf signaling. Finally, we present a classification of known tyrosine kinase inhibitors according to their specificity for the Egf pathway. In conclusion, we show that developmental indicators can help to discriminate between specific effects on the target pathway from off-target effects in molecularly targeted drug screening experiments in whole animal systems. - Highlights: • We analyze the functions of Egf signaling on zebrafish development. • Genetic blocking of Egf expression causes cartilage, myelin and circulatory defects. • Chemical inhibition of Egf receptor function causes similar defects. • Developmental defects can reveal the specificity of Egf pathway inhibitors.

  14. The role of high-level calculations in the assignment of the Q-band spectra of chlorophyll

    SciTech Connect

    Reimers, Jeffrey R.; Cai, Zheng-Li; Kobayashi, Rika; Rätsep, Margus; Freiberg, Arvi; Krausz, Elmars

    2014-10-06

    We recently established a novel assignment of the visible absorption spectrum of chlorophyll-a that sees the two components Q{sub x} and Q{sub y} of the low-energy Q band as being intrinsically mixed by non-adiabatic coupling. This ended 50 years debate as to the nature of the Q bands, with prior discussion poised only in the language of the Born-Oppenheimer and Condon approximations. The new assignment presents significant ramifications for exciton transport and quantum coherence effects in photosystems. Results from state of the art electronic structure calculations have always been used to justify assignments, but quantitative inaccuracies and systematic failures have historically limited usefulness. We examine the role of CAM-B3LYP time-dependent density-functional theory (TD-DFT) and Symmetry Adapted Cluster-Configuration Interaction (SAC-CI) calculations in first showing that all previous assignments were untenable, in justifying the new assignment, in making some extraordinary predictions that were vindicated by the new assignment, and in then identifying small but significant anomalies in the extensive experimental data record.

  15. Quadratic partial eigenvalue assignment in large-scale stochastic dynamic systems for resilient and economic design

    SciTech Connect

    Das, Sonjoy; Goswami, Kundan; Datta, Biswa N.

    2014-12-10

    Failure of structural systems under dynamic loading can be prevented via active vibration control which shifts the damped natural frequencies of the systems away from the dominant range of loading spectrum. The damped natural frequencies and the dynamic load typically show significant variations in practice. A computationally efficient methodology based on quadratic partial eigenvalue assignment technique and optimization under uncertainty has been formulated in the present work that will rigorously account for these variations and result in an economic and resilient design of structures. A novel scheme based on hierarchical clustering and importance sampling is also developed in this work for accurate and efficient estimation of probability of failure to guarantee the desired resilience level of the designed system. Numerical examples are presented to illustrate the proposed methodology.

  16. Infrared and Raman spectra, DFT-calculations and spectral assignments of germacyclohexane

    SciTech Connect

    Aleksa, V. Ozerenskis, D.; Pucetaite, M.; Sablinskas, V.; Cotter, C.; Guirgis, G. A.

    2015-03-30

    Raman spectra of germacyclohexane in liquid and solid states were recorded and depolarization data obtained. Infrared absorption spectra of the vapor and liquid have been studied. The wavenumbers of the vibrational modes were derived in the harmonic and anharmonic approximation in B3LYP/ccpVTZ calculations. According to the calculations, germacyclohexane exists in the stable chair conformation, whereas a possible twist form should have more than 15 kJ·mol{sup -1} higher enthalpy of formation what makes this conformer experimentally not observable. The 27 A' and 21 A'' fundamentals were assigned on the basis of the calculations and infrared and Raman band intensities, contours of gas phase infrared spectral bands and Raman depolarization measurements. An average discrepancy of ca. 0.77 % was found between the observed and the calculated anharmonic wavenumbers for the 48 modes. Substitution of carbon atom with Ge atom in the cyclohexane ring is reasoning flattening of the ring.

  17. FOAM (Functional Ontology Assignments for Metagenomes): A Hidden Markov Model (HMM) database with environmental focus

    SciTech Connect

    Prestat, Emmanuel; David, Maude M.; Hultman, Jenni; Ta , Neslihan; Lamendella, Regina; Dvornik, Jill; Mackelprang, Rachel; Myrold, David D.; Jumpponen, Ari; Tringe, Susannah G.; Holman, Elizabeth; Mavromatis, Konstantinos; Jansson, Janet K.

    2014-09-26

    A new functional gene database, FOAM (Functional Ontology Assignments for Metagenomes), was developed to screen environmental metagenomic sequence datasets. FOAM provides a new functional ontology dedicated to classify gene functions relevant to environmental microorganisms based on Hidden Markov Models (HMMs). Sets of aligned protein sequences (i.e. ‘profiles’) were tailored to a large group of target KEGG Orthologs (KOs) from which HMMs were trained. The alignments were checked and curated to make them specific to the targeted KO. Within this process, sequence profiles were enriched with the most abundant sequences available to maximize the yield of accurate classifier models. An associated functional ontology was built to describe the functional groups and hierarchy. FOAM allows the user to select the target search space before HMM-based comparison steps and to easily organize the results into different functional categories and subcategories. FOAM is publicly available at http://portal.nersc.gov/project/m1317/FOAM/.

  18. Spatial assignment of symmetry adapted perturbation theory interaction energy components: The atomic SAPT partition

    SciTech Connect

    Parrish, Robert M.; Sherrill, C. David

    2014-07-28

    We develop a physically-motivated assignment of symmetry adapted perturbation theory for intermolecular interactions (SAPT) into atom-pairwise contributions (the A-SAPT partition). The basic precept of A-SAPT is that the many-body interaction energy components are computed normally under the formalism of SAPT, following which a spatially-localized two-body quasiparticle interaction is extracted from the many-body interaction terms. For electrostatics and induction source terms, the relevant quasiparticles are atoms, which are obtained in this work through the iterative stockholder analysis (ISA) procedure. For the exchange, induction response, and dispersion terms, the relevant quasiparticles are local occupied orbitals, which are obtained in this work through the Pipek-Mezey procedure. The local orbital atomic charges obtained from ISA additionally allow the terms involving local orbitals to be assigned in an atom-pairwise manner. Further summation over the atoms of one or the other monomer allows for a chemically intuitive visualization of the contribution of each atom and interaction component to the overall noncovalent interaction strength. Herein, we present the intuitive development and mathematical form for A-SAPT applied in the SAPT0 approximation (the A-SAPT0 partition). We also provide an efficient series of algorithms for the computation of the A-SAPT0 partition with essentially the same computational cost as the corresponding SAPT0 decomposition. We probe the sensitivity of the A-SAPT0 partition to the ISA grid and convergence parameter, orbital localization metric, and induction coupling treatment, and recommend a set of practical choices which closes the definition of the A-SAPT0 partition. We demonstrate the utility and computational tractability of the A-SAPT0 partition in the context of side-on cation-π interactions and the intercalation of DNA by proflavine. A-SAPT0 clearly shows the key processes in these complicated noncovalent interactions, in

  19. Questions concerning DOE's assignment of operating and testing responsibilities for OTEC-1

    SciTech Connect

    Not Available

    1981-06-30

    OTEC is one of the potential energy sources being developed to provide alternatives for reducing the Nation's dependence on imported oil. When developed, OTEC is to use the temperature variants of the ocean to produce electricity and energy intensive products. OTEC-1 is a major part of DOE's developmental program for OTEC. It is a floating test facility designed primarily for conducting sea tests of the cleanability and performance of heat exchangers, a major component of OTEC systems. Related OTEC subsystems are also being tested. OTEC-1 was to be accomplished in three phases; design (phase I); construction (phase II); and operations and testing (phase III). In July 1977, DOE contracted with TRW, Inc. to design and develop the heat exchanger to be used on OTEC-1. In September 1978, DOE contracted with Global Marine to refurbish, retrofit, and deploy an old Navy ship with OTEC subsystems including TRW's heat exchanger. Together Global Marine and TRW were the OTEC-1 design and construction contractors for phases I and II with Global Marine having overall responsibility for integrating its and TRW's work. Global Marine's contract also included an option for performing work in phase III.

  20. Developmental exposure to a commercial PBDE mixture, DE-71: neurobehavioral, hormonal, and reproductive effects.

    SciTech Connect

    Kodavanti, Prasada; Coburn, Cary; Moser, Virginia; MacPhail, Robert; Fenton, Suzanne; Stoker, Tammy; Birnbaum, Linda

    2010-06-01

    Developmental effects of polybrominated diphenyl ethers (PBDEs) have been suspected due to their structural similarities to polychlorinated biphenyls (PCBs). This study evaluated neurobehavioral, hormonal, and reproductive effects in rat offspring perinatally exposed to a widely used pentabrominated commercial mixture, DE-71. Pregnant Long-Evans rats were exposed to 0, 1.7, 10.2, or 30.6 mg/kg/day DE-71 in corn oil by oral gavage from gestational day 6 to weaning. DE-71 did not alter maternal or male offspring body weights. However, female offspring were smaller compared with controls from postnatal days (PNDs) 35-60. Although several neurobehavioral endpoints were assessed, the only statistically significant behavioral finding was a dose-by-age interaction in the number of rears in an open-field test. Developmental exposure to DE-71 caused severe hypothyroxinemia in the dams and early postnatal offspring. DE-71 also affected anogenital distance and preputial separation in male pups. Body weight gain over time, reproductive tissue weights, and serum testosterone concentrations at PND 60 were not altered. Mammary gland development of female offspring was significantly affected at PND 21. Congener-specific analysis of PBDEs indicated accumulation in all tissues examined. Highest PBDE concentrations were found in fat including milk, whereas blood had the lowest concentrations on a wet weight basis. PBDE concentrations were comparable among various brain regions. Thus, perinatal exposure to DE-71 leads to accumulation of PBDE congeners in various tissues crossing blood-placenta and blood-brain barriers, causing subtle changes in some parameters of neurobehavior and dramatic changes in circulating thyroid hormone levels, as well as changes in both male and female reproductive endpoints. Some of these effects are similar to those seen with PCBs, and the persistence of these changes requires further investigation.

  1. Assigning unique identification numbers to new user accounts and groups in a computing environment with multiple registries

    DOEpatents

    DeRobertis, Christopher V.; Lu, Yantian T.

    2010-02-23

    A method, system, and program storage device for creating a new user account or user group with a unique identification number in a computing environment having multiple user registries is provided. In response to receiving a command to create a new user account or user group, an operating system of a clustered computing environment automatically checks multiple registries configured for the operating system to determine whether a candidate identification number for the new user account or user group has been assigned already to one or more existing user accounts or groups, respectively. The operating system automatically assigns the candidate identification number to the new user account or user group created in a target user registry if the checking indicates that the candidate identification number has not been assigned already to any of the existing user accounts or user groups, respectively.

  2. Quantitative IR Spectrum and Vibrational Assignments for Glycolaldehyde Vapor: Glycolaldehyde Measurements in Biomass Burning Plumes

    SciTech Connect

    Johnson, Timothy J.; Sams, Robert L.; Profeta, Luisa T.; Akagi, Sheryl; Burling, Ian R.; Yokelson, Robert J.; Williams, Stephen D.

    2013-04-15

    Glycolaldehyde (GA, 2-hydroxyethanal, C2H4O2) is a semi-volatile molecule of atmospheric importance, recently proposed as a precursor in the formation of aqueous-phase secondary organic aerosol (SOA). There are few methods to measure glycolaldehyde vapor, but infrared spectroscopy has been used successfully. Using vetted protocols we have completed the first assignment of all fundamental vibrational modes and derived quantitative IR absorption band strengths using both neat and pressure-broadened GA vapor. Even though GA is problematic due to its propensity to both dimerize and condense, our intensities agree well with the few previously published values. Using the reference ?10 band Q-branch at 860.51 cm-1, we have also determined GA mixing ratios in biomass burning plumes generated by field and laboratory burns of fuels from the southeastern and southwestern United States, including the first field measurements of glycolaldehyde in smoke. The GA emission factors were anti-correlated with modified combustion efficiency confirming release of GA from smoldering combustion. The GA emission factors (g of GA emitted per kg dry biomass burned on a dry mass basis) had a low dependence on fuel type consistent with the production mechanism being pyrolysis of cellulose. GA was emitted at 0.23 0.13% of CO from field fires and we calculate that it accounts for ~18% of the aqueous-phase SOA precursors that we were able to measure.

  3. FOAM (Functional Ontology Assignments for Metagenomes): A Hidden Markov Model (HMM) database with environmental focus

    DOE PAGES [OSTI]

    Prestat, Emmanuel; David, Maude M.; Hultman, Jenni; Ta , Neslihan; Lamendella, Regina; Dvornik, Jill; Mackelprang, Rachel; Myrold, David D.; Jumpponen, Ari; Tringe, Susannah G.; et al

    2014-09-26

    A new functional gene database, FOAM (Functional Ontology Assignments for Metagenomes), was developed to screen environmental metagenomic sequence datasets. FOAM provides a new functional ontology dedicated to classify gene functions relevant to environmental microorganisms based on Hidden Markov Models (HMMs). Sets of aligned protein sequences (i.e. ‘profiles’) were tailored to a large group of target KEGG Orthologs (KOs) from which HMMs were trained. The alignments were checked and curated to make them specific to the targeted KO. Within this process, sequence profiles were enriched with the most abundant sequences available to maximize the yield of accurate classifier models. An associatedmore » functional ontology was built to describe the functional groups and hierarchy. FOAM allows the user to select the target search space before HMM-based comparison steps and to easily organize the results into different functional categories and subcategories. FOAM is publicly available at http://portal.nersc.gov/project/m1317/FOAM/.« less

  4. Acquisition Guide Chapter 4.6- Assigning Identifying Numbers Outside of the Strategic Integrated Procurement Enterprise System (STRIPES)

    Energy.gov [DOE]

    The subject guide chapter provides guidance on the DOE's procedures for assigning identifying numbers to all new requisitions, solicitations and business instruments processed outside of STRIPES. This Guide Chapter does not apply to instrument numbers issued and business instruments awarded prior to the deployment of STRIPES at the DOE.

  5. Molecular cloning and developmental expression of plakophilin 2 in zebrafish

    SciTech Connect

    Moriarty, Miriam A.; Martin, Eva D.; Byrnes, Lucy; Grealy, Maura

    2008-02-29

    Armadillo proteins are involved in providing strength and support to cells and tissues, nuclear transport, and transcriptional activation. In this report, we describe the identification and characterisation of the cDNA of the desmosomal armadillo protein plakophilin 2 in zebrafish. The 2448 bp coding sequence encodes a predicted 815 amino acid protein, with nine armadillo repeats characteristic of the p120-catenin subfamily. It shares conserved N-glycosylation, myristoylation, and glycogen synthase kinase 3, casein kinase 2, and protein kinase C phosphorylation sites with mammalian armadillo proteins including plakoglobin and {beta}-catenin. Semi-quantitative reverse transcription polymerase chain reaction and whole mount in situ hybridisation show that it is expressed both maternally and zygotically. It is ubiquitously expressed during blastula stages but becomes restricted to epidermal and cardiac tissue during gastrulation. These results provide evidence that zebrafish plakophilin 2 is developmentally regulated with potential roles in cell adhesion, signalling, and cardiac and skin development.

  6. Developmental toxicity of low generation PAMAM dendrimers in zebrafish

    SciTech Connect

    King Heiden, Tisha C.; Dengler, Emelyne; Kao, Weiyuan John; Heideman, Warren; Peterson, Richard E.

    2007-11-15

    Biological molecules and intracellular structures operate at the nanoscale; therefore, development of nanomedicines shows great promise for the treatment of disease by using targeted drug delivery and gene therapies. PAMAM dendrimers, which are highly branched polymers with low polydispersity and high functionality, provide an ideal architecture for construction of effective drug carriers, gene transfer devices and imaging of biological systems. For example, dendrimers bioconjugated with selective ligands such as Arg-Gly-Asp (RGD) would theoretically target cells that contain integrin receptors and show potential for use as drug delivery devices. While RGD-conjugated dendrimers are generally considered not to be cytotoxic, there currently exists little information on the risks that such materials pose to human health. In an effort to compliment and extend the knowledge gleaned from cell culture assays, we have used the zebrafish embryo as a rapid, medium throughput, cost-effective whole-animal model to provide a more comprehensive and predictive developmental toxicity screen for nanomaterials such as PAMAM dendrimers. Using the zebrafish embryo, we have assessed the developmental toxicity of low generation (G3.5 and G4) PAMAM dendrimers, as well as RGD-conjugated forms for comparison. Our results demonstrate that G4 dendrimers, which have amino functional groups, are toxic and attenuate growth and development of zebrafish embryos at sublethal concentrations; however, G3.5 dendrimers, with carboxylic acid terminal functional groups, are not toxic to zebrafish embryos. Furthermore, RGD-conjugated G4 dendrimers are less potent in causing embryo toxicity than G4 dendrimers. RGD-conjugated G3.5 dendrimers do not elicit toxicity at the highest concentrations tested and warrant further study for use as a drug delivery device.

  7. Borehole Logging Methods for Exploration and Evaluation of Uranium Deposits

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    (1967) | Department of Energy Borehole Logging Methods for Exploration and Evaluation of Uranium Deposits (1967) Borehole Logging Methods for Exploration and Evaluation of Uranium Deposits (1967) Borehole Logging Methods for Exploration and Evaluation of Uranium Deposits (1967) Borehole Logging Methods for Exploration and Evaluation of Uranium Deposits (1967) (13.97 MB) More Documents & Publications Gamma-Ray Logging Workshop (February 1981) Grade Assignments for Models Used for

  8. Arranging Prescription Drug Coverage for Extended Stays (Travel or Long-Term Work Assignments) When Outside the United States

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Arranging Prescription Drug Coverage for Extended Stays (Travel or Long-Term Work Assignments) When Outside the United States Planning an extended vacation or working abroad? rx_lanl_override_0311 Maintaining prescription coverage and accessing care for long-term stays abroad What you need to know about override requests and obtaining Rx drugs. Your BCBSNM prescription drug coverage limits override requests to a 90-day supply. Override requests cannot be approved - and are not available -

  9. Developmental long trace profiler using optimally aligned mirror based pentaprism

    SciTech Connect

    Barber, Samuel K; Morrison, Gregory Y; Yashchuk, Valeriy V; Gubarev, Mikhail V; Geckeler, Ralf D.; Buchheim, Jana; Siewert, Frank; Zeschke, Thomas

    2010-12-20

    A low-budget surface slope measuring instrument, the Developmental Long Trace Profiler (DLTP), was recently brought into operation at the Advanced Light Source Optical Metrology Laboratory. The instrument is based on a precisely calibrated autocollimator and a movable pentaprism. The capability of the DLTP to achieve sub-microradian surface slope metrology has been verified via cross-comparison measurements with other high-performance slope measuring instruments when measuring the same high-quality test optics. In the present work, a further improvement of the DLTP is achieved by replacing the existing bulk pentaprism with a specially designed mirror based pentaprism. A mirror based pentaprism offers the possibility to eliminate systematic errors introduced by inhomogeneity of the optical material and fabrication imperfections of a bulk pentaprism. We provide the details of the mirror based pentaprism design and describe an original experimental procedure for precision mutual alignment of the mirrors. The algorithm of the alignment procedure and its efficiency are verified with rigorous ray tracing simulations. Results of measurements of a spherically curved test mirror and a flat test mirror using the original bulk pentaprism are compared with measurements using the new mirror based pentaprism, demonstrating the improved performance.

  10. Inhalation developmental toxicology studies: Gallium arsenide in mice and rats

    SciTech Connect

    Mast, T.J.; Greenspan, B.J.; Dill, J.A.; Stoney, K.H.; Evanoff, J.J.; Rommereim, R.L.

    1990-12-01

    Gallium arsenide is a crystalline compound used extensively in the semiconductor industry. Workers preparing solar cells and gallium arsenide ingots and wafers are potentially at risk from the inhalation of gallium arsenide dust. The potential for gallium arsenide to cause developmental toxicity was assessed in Sprague- Dawley rats and CD-1 (Swiss) mice exposed to 0, 10, 37, or 75 mg/m{sup 3} gallium arsenide, 6 h/day, 7 days/week. Each of the four treatment groups consisted of 10 virgin females (for comparison), and {approx}30 positively mated rats or {approx}24 positively mated mice. Mice were exposed on 4--17 days of gestation (dg), and rats on 4--19 dg. The day of plug or sperm detection was designated as 0 dg. Body weights were obtained throughout the study period, and uterine and fetal body weights were obtained at sacrifice (rats, 20 dg; mice, 18 dg). Implants were enumerated and their status recorded. Live fetuses were sexed and examined for gross, visceral, skeletal, and soft-tissue craniofacial defects. Gallium and arsenic concentrations were determined in the maternal blood and uterine contents of the rats (3/group) at 7, 14, and 20 dg. 37 refs., 11 figs., 30 tabs.

  11. Inhalation developmental toxicology studies: Acetonitrile in rats. Final report

    SciTech Connect

    Mast, T.J.; Weigel, R.J.; Westerberg, R.B.; Boyd, P.J.; Hayden, B.K.; Evanoff, J.J.; Rommereim, R.L.

    1994-02-01

    The potential for acetonitrile to cause developmental toxicity was assessed in Sprague-Dawley rats exposed to 0, 100, 400, or 1200 ppM acetonitrile, 6 hours/day, 7 days/week. Exposure of rats to these concentrations of acetonitrile resulted in mortality in the 1200 ppM group (2/33 pregnant females; 1/10 non-pregnant females). However, there were no treatment-related effects upon body weights or reproduction indices at any exposure level, nor was there a significant increase in the incidence of fetal malformations or variations. The only effect observed in the fetuses was a slight, but not statiscally significant, exposure-correlated increase in the incidence of supernumerary ribs. Determination of acetonitrile and cyanide concentrations in maternal rat blood showed that acetonitrile concentration in the blood increased with exposure concentration for all exposed maternal rats. Detectable amounts of cyanide in the blood were found only in the rats exposed to 1200 ppM acetonitrile ({approximately}2 {mu}g cyanide/g of blood).

  12. Evaluation of the DHCE Experiment

    SciTech Connect

    Greenwood, Lawrence R.; Baldwin, David L.; Hollenberg, Glenn W.; Kurtz, Richard J.

    2002-03-31

    The Dynamic Helium Charging Experiment (DHCE) experiment was conducted in the Fast Flux Test Facility (FFTF) during cycle 12, which was completed in 1992. The purpose of the experiment was to enhance helium generation in vanadium alloys to simulate fusion reactor helium-to-dpa ratios with a target goal of 4-5 appm He/dpa. The Fusion Materials Science Program is considering mounting another experiment in hopes of gathering additional data on the effect of helium on the mechanical and physical properties of vanadium structural materials. Pacific Northwest National Laboratory was assigned the task of evaluating the feasibility of conducting another DHCE experiment by carefully evaluating the results obtained of the first DHCE experiment. This report summarizes the results of our evaluation and presents recommendations for consideration by the Materials Science Coordinators Organization.

  13. NbF{sub 5} and TaF{sub 5}: Assignment of {sup 19}F NMR resonances and chemical bond analysis from GIPAW calculations

    SciTech Connect

    Biswal, Mamata; Body, Monique; Legein, Christophe; Sadoc, Aymeric; Boucher, Florent

    2013-11-15

    The {sup 19}F isotropic chemical shifts (?{sub iso}) of two isomorphic compounds, NbF{sub 5} and TaF{sub 5}, which involve six nonequivalent fluorine sites, have been experimentally determined from the reconstruction of 1D {sup 19}F MAS NMR spectra. In parallel, the corresponding {sup 19}F chemical shielding tensors have been calculated using the GIPAW method for both experimental and DFT-optimized structures. Furthermore, the [M{sub 4}F{sub 20}] units of NbF{sub 5} and TaF{sub 5} being held together by van der Waals interactions, the relevance of Grimme corrections to the DFT optimization processes has been evaluated. However, the semi-empirical dispersion correction term introduced by such a method does not show any significant improvement. Nonetheless, a complete and convincing assignment of the {sup 19}F NMR lines of NbF{sub 5} and TaF{sub 5} is obtained, ensured by the linearity between experimental {sup 19}F ?{sub iso} values and calculated {sup 19}F isotropic chemical shielding ?{sub iso} values. The effects of the geometry optimizations have been carefully analyzed, confirming among other matters, the inaccuracy of the experimental structure of NbF{sub 5}. The relationships between the fluorine chemical shifts, the nature of the fluorine atoms (bridging or terminal), the position of the terminal ones (opposite or perpendicular to the bridging ones), the fluorine charges, the ionicity and the length of the MF bonds have been established. Additionally, for three of the {sup 19}F NMR lines of NbF{sub 5}, distorted multiplets, arising from {sup 1}J-coupling and residual dipolar coupling between the {sup 19}F and {sup 93}Nb nuclei, were simulated yielding to values of {sup 93}Nb{sup 19}F {sup 1}J-coupling for the corresponding fluorine sites. - Graphical abstract: The complete assignment of the {sup 19}F NMR lines of NbF{sub 5} and TaF{sub 5} allow establishing relationships between the {sup 19}F ?{sub iso} values, the nature of the fluorine atoms (bridging or

  14. A Bayesian method for using simulator data to enhance human error probabilities assigned by existing HRA methods

    DOE PAGES [OSTI]

    Groth, Katrina M.; Smith, Curtis L.; Swiler, Laura P.

    2014-04-05

    In the past several years, several international agencies have begun to collect data on human performance in nuclear power plant simulators [1]. This data provides a valuable opportunity to improve human reliability analysis (HRA), but there improvements will not be realized without implementation of Bayesian methods. Bayesian methods are widely used in to incorporate sparse data into models in many parts of probabilistic risk assessment (PRA), but Bayesian methods have not been adopted by the HRA community. In this article, we provide a Bayesian methodology to formally use simulator data to refine the human error probabilities (HEPs) assigned by existingmore » HRA methods. We demonstrate the methodology with a case study, wherein we use simulator data from the Halden Reactor Project to update the probability assignments from the SPAR-H method. The case study demonstrates the ability to use performance data, even sparse data, to improve existing HRA methods. Furthermore, this paper also serves as a demonstration of the value of Bayesian methods to improve the technical basis of HRA.« less

  15. A Bayesian method for using simulator data to enhance human error probabilities assigned by existing HRA methods

    SciTech Connect

    Katrinia M. Groth; Curtis L. Smith; Laura P. Swiler

    2014-08-01

    In the past several years, several international organizations have begun to collect data on human performance in nuclear power plant simulators. The data collected provide a valuable opportunity to improve human reliability analysis (HRA), but these improvements will not be realized without implementation of Bayesian methods. Bayesian methods are widely used to incorporate sparse data into models in many parts of probabilistic risk assessment (PRA), but Bayesian methods have not been adopted by the HRA community. In this paper, we provide a Bayesian methodology to formally use simulator data to refine the human error probabilities (HEPs) assigned by existing HRA methods. We demonstrate the methodology with a case study, wherein we use simulator data from the Halden Reactor Project to update the probability assignments from the SPAR-H method. The case study demonstrates the ability to use performance data, even sparse data, to improve existing HRA methods. Furthermore, this paper also serves as a demonstration of the value of Bayesian methods to improve the technical basis of HRA.

  16. Fluoride-elicited developmental testicular toxicity in rats: Roles of endoplasmic reticulum stress and inflammatory response

    SciTech Connect

    Zhang, Shun; Jiang, Chunyang; Liu, Hongliang; Guan, Zhizhong; Zeng, Qiang; Zhang, Cheng; Lei, Rongrong; Xia, Tao; Gao, Hui; Yang, Lu; Chen, Yihu; Wu, Xue; Zhang, Xiaofei; Cui, Yushan; Yu, Linyu; Wang, Zhenglun; Wang, Aiguo

    2013-09-01

    Long-term excessive fluoride intake is known to be toxic and can damage a variety of organs and tissues in the human body. However, the molecular mechanisms underlying fluoride-induced male reproductive toxicity are not well understood. In this study, we used a rat model to simulate the situations of human exposure and aimed to evaluate the roles of endoplasmic reticulum (ER) stress and inflammatory response in fluoride-induced testicular injury. Sprague–Dawley rats were administered with sodium fluoride (NaF) at 25, 50 and 100 mg/L via drinking water from pre-pregnancy to gestation, birth and finally to post-puberty. And then the testes of male offspring were studied at 8 weeks of age. Our results demonstrated that fluoride treatment increased MDA accumulation, decreased SOD activity, and enhanced germ cell apoptosis. In addition, fluoride elevated mRNA and protein levels of glucose-regulated protein 78 (GRP78), inositol requiring ER-to-nucleus signal kinase 1 (IRE1), and C/EBP homologous protein (CHOP), indicating activation of ER stress signaling. Furthermore, fluoride also induced testicular inflammation, as manifested by gene up-regulation of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), in a nuclear factor-κB (NF-κB)-dependent manner. These were associated with marked histopathological lesions including injury of spermatogonia, decrease of spermatocytes and absence of elongated spermatids, as well as severe ultrastructural abnormalities in testes. Taken together, our results provide compelling evidence that ER stress and inflammation would be novel and significant mechanisms responsible for fluoride-induced disturbance of spermatogenesis and germ cell loss in addition to oxidative stress. - Highlights: • We used a rat model to simulate the situations of human fluoride (F) exposure. • Developmental F exposure induces testicular damage related with oxidative stress.

  17. Developmental nephrotoxicity of aristolochic acid in a zebrafish model

    SciTech Connect

    Ding, Yu-Ju; Chen, Yau-Hung

    2012-05-15

    Aristolochic acid (AA) is a component of Aristolochia plant extracts which is used as a treatment for different pathologies and their toxicological effects have not been sufficiently studied. The aim of this study was to evaluate AA-induced nephrotoxicity in zebrafish embryos. After soaking zebrafish embryos in AA, the embryos displayed malformed kidney phenotypes, such as curved, cystic pronephric tubes, pronephric ducts, and cases of atrophic glomeruli. The percentages of embryos with malformed kidney phenotypes increased as the exposure dosages of AA increased. Furthermore, AA-treated embryos exhibited significantly reduced glomerular filtration rates (GFRs) in comparison with mock-control littermates (mock-control: 100 ± 2.24% vs. 10 ppm AA treatment for 3–5 h: 71.48 ± 18.84% ∼ 39.41 ± 15.88%), indicating that AA treatment not only caused morphological kidney changes but also induced renal failure. In addition to kidney malformations, AA-treated zebrafish embryos also exhibited deformed hearts, swollen pericardiums, impaired blood circulation and the accumulation(s) of red blood cells. Whole-mount in situ hybridization studies using cmlc2 and wt1b as riboprobes indicated that the kidney is more sensitive than the heart to AA damage. Real-time PCR showed that AA can up-regulate the expression of proinflammatory genes like TNFα, cox2 and mpo. These results support the following conclusions: (1) AA-induced renal failure is mediated by inflammation, which causes circulation dysfunction followed by serious heart malformation; and (2) the kidney is more sensitive than the heart to AA injury. -- Highlights: ► Zebrafish were used to evaluate aristolochic acid (AA)-induced nephrotoxicity. ► AA-treated zebrafish embryos exhibited deformed heart as well as malformed kidney. ► Kidney is more sensitive to AA injury than the heart.

  18. SES CANDIDATE DEVELOPMENT PROGRAM

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    5 (11-03) SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Candidate Developmental Assignment Evaluation DATE:_______________ NAME OF SES CANDIDATE TITLE OF POSITION LOCATION ASSIGNMENT DURATION: Which Executive Core Qualification(s) was this assignment intended to meet? Leading Change Leading People Results Driven Business Acumen Building Coalitions/Communication Please provide a brief description of your assignment. Did the experience meet your expectation? Was this a good

  19. METHODOLOGY & CALCULATIONS FOR THE ASSIGNMENT OF WASTE GROUPS FOR THE LARGE UNDERGROUND WASTE STORAGE TANKS AT THE HANFORD SITE

    SciTech Connect

    BARKER, S.A.

    2006-07-27

    Waste stored within tank farm double-shell tanks (DST) and single-shell tanks (SST) generates flammable gas (principally hydrogen) to varying degrees depending on the type, amount, geometry, and condition of the waste. The waste generates hydrogen through the radiolysis of water and organic compounds, thermolytic decomposition of organic compounds, and corrosion of a tank's carbon steel walls. Radiolysis and thermolytic decomposition also generates ammonia. Nonflammable gases, which act as dilutents (such as nitrous oxide), are also produced. Additional flammable gases (e.g., methane) are generated by chemical reactions between various degradation products of organic chemicals present in the tanks. Volatile and semi-volatile organic chemicals in tanks also produce organic vapors. The generated gases in tank waste are either released continuously to the tank headspace or are retained in the waste matrix. Retained gas may be released in a spontaneous or induced gas release event (GRE) that can significantly increase the flammable gas concentration in the tank headspace as described in RPP-7771. The document categorizes each of the large waste storage tanks into one of several categories based on each tank's waste characteristics. These waste group assignments reflect a tank's propensity to retain a significant volume of flammable gases and the potential of the waste to release retained gas by a buoyant displacement event. Revision 5 is the annual update of the methodology and calculations of the flammable gas Waste Groups for DSTs and SSTs.

  20. METHODOLOGY & CALCULATIONS FOR THE ASSIGNMENT OF WASTE FOR THE LARGE UNDERGROUND WASTE STORAGE TANKS AT THE HANFORD SITE

    SciTech Connect

    TU, T.A.

    2007-01-04

    Waste stored within tank farm double-shell tanks (DST) and single-shell tanks (SST) generates flammable gas (principally hydrogen) to varying degrees depending on the type, amount, geometry, and condition of the waste. The waste generates hydrogen through the radiolysis of water and organic compounds, thermolytic decomposition of organic compounds, and corrosion of a tank's carbon steel walls. Radiolysis and thermolytic decomposition also generates ammonia. Nonflammable gases, which act as dilutents (such as nitrous oxide), are also produced. Additional flammable gases (e.g., methane) are generated by chemical reactions between various degradation products of organic chemicals present in the tanks. Volatile and semi-volatile organic chemicals in tanks also produce organic vapors. The generated gases in tank waste are either released continuously to the tank headspace or are retained in the waste matrix. Retained gas may be released in a spontaneous or induced gas release event (GRE) that can significantly increase the flammable gas concentration in the tank headspace as described in RPP-7771, Flammable Gas Safety Isme Resolution. Appendices A through I provide supporting information. The document categorizes each of the large waste storage tanks into one of several categories based on each tank's waste and characteristics. These waste group assignments reflect a tank's propensity to retain a significant volume of flammable gases and the potential of the waste to release retained gas by a buoyant displacement event. Revision 6 is the annual update of the flammable gas Waste Groups for DSTs and SSTs.

  1. 1H, 13C, and 15N backbone and side chain resonance assignments of thermophilic Geobacillus kaustophilus cyclophilin-A

    SciTech Connect

    Holliday, Michael; Zhang, Fengli; Isern, Nancy G.; Armstrong, Geoffrey S.; Eisenmesser, Elan Z.

    2014-04-01

    Cyclophilins catalyze the reversible peptidyl-prolyl isomerization of their substrates and are present across all kingdoms of life from humans to bacteria. Although numerous biological roles have now been discovered for cyclophilins, their function was initially ascribed to their chaperone-like activity in protein folding where they catalyze the often rate-limiting step of proline isomerization. This chaperone-like activity may be especially important under extreme conditions where cyclophilins are often over expressed, such as in tumors for human cyclophilins {Lee, 2010 #1167}, but also in organisms that thrive under extreme conditions, such as theromophilic bacteria. Moreover, the reversible nature of the peptidyl-prolyl isomerization reaction catalyzed by cyclophilins has allowed these enzymes to serve as model systems for probing the role of conformational changes during catalytic turnover {Eisenmesser, 2002 #20;Eisenmesser, 2005 #203}. Thus, we present here the resonance assignments of a thermophilic cyclophilin from Geobacillus kaustophilus derived from deep-sea sediment {Takami, 2004 #1384}. This thermophilic cyclophilin may now be studied at a variety of temperatures to provide insight into the comparative structure, dynamics, and catalytic mechanism of cyclophilins.

  2. Nondestructive evaluation

    SciTech Connect

    Martz, H.E.

    1997-02-01

    Research reported in the thrust area of nondestructive evaluation includes: advanced 3-D imaging technologies; new techniques in laser ultrasonic testing; infrared computed tomography for thermal NDE of materials, structures, sources, and processes; automated defect detection for large laser optics; multistatic micropower impulse radar imaging for nondestructive evaluation; and multi-modal NDE for AVLIS pod shielding components.

  3. A cohort study of developmental polychlorinated biphenyl (PCB) exposure in relation to post-vaccination antibody response at 6-months of age

    SciTech Connect

    Jusko, Todd A.; De Roos, Anneclaire J.; Schwartz, Stephen M.; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA ; Paige Lawrence, B.; Palkovicova, Lubica; Nemessanyi, Tomas; Drobna, Beata; Fabisikova, Anna; Kocan, Anton; Sonneborn, Dean; Jahnova, Eva; Kavanagh, Terrance J.; Trnovec, Tomas; Hertz-Picciotto, Irva

    2010-05-15

    Background: Extensive experimental data in animals indicate that exposure to polychlorinated biphenyls (PCBs) during pregnancy leads to changes in offspring immune function during the postnatal period. Whether developmental PCB exposure influences immunologic development in humans has received little study. Methods: The study population was 384 mother-infant pairs recruited from two districts of eastern Slovakia for whom prospectively collected maternal, cord, and 6-month infant blood specimens were available. Several PCB congeners were measured in maternal, cord, and 6-month infant sera by high-resolution gas chromatography with electron capture detection. Concentrations of IgG-specific anti-haemophilus influenzae type b, tetanus toxoid, and diphtheria toxoid were assayed in 6-month infant sera using ELISA methods. Multiple linear regression was used to estimate the relation between maternal, cord, and 6-month infant PCB concentrations and the antibody concentrations evaluated at 6-months of age. Results: Overall, there was little evidence of an association between infant antibody concentrations and PCB measures during the pre- and early postnatal period. In addition, our results did not show specificity in terms of associations limited to a particular developmental period (e.g. pre- vs. postnatal), a particular antibody, or a particular PCB congener. Conclusions: At the PCB concentrations measured in this cohort, which are high relative to most human populations today, we did not detect an association between maternal or early postnatal PCB exposure and specific antibody responses at 6-months of age.

  4. Nonlinear, noniterative, single-distance phase retrieval and developmental biology

    SciTech Connect

    Moosmann, Julian; Altapova, Venera; Haenschke, Daniel; Hofmann, Ralf; Baumbach, Tilo

    2012-05-17

    For coherent X-ray imaging, based on phase contrast through free-space Fresnel propagation, we discuss two noniterative, nonlinear approaches to the phase-retrieval problem from a single-distance intensity map of a pure-phase object. On one hand, a perturbative set-up is proposed where nonlinear corrections to the linearized transport-of-intensity situation are expanded in powers of the object-detector distance z and are evaluated in terms of the linear estimate. On the other hand, a nonperturbative projection algorithm, which is based on the (linear and local) contrast-transfer function (CTF), works with an effective phase in Fourier space. This effective phase obeys a modified CTF relation between intensity contrast at z > 0 and phase contrast at z= 0: Unphysical singularities of the local CTF model are cut off to yield 'quasiparticles' in analogy to the theory of the Fermi liquid. By identifying the positions of the zeros of the Fourier transformed intensity contrast as order parameters for the dynamical breaking of scaling symmetry we investigate the phase structure of the forward-propagation problem when interpreted as a statistical system. Results justify the quasiparticle approach for a wide range of intermediary phase variations. The latter algorithm is applied to data from biological samples recorded at the beamlines TopoTomo and ID19 at ANKA and ESRF, respectively.

  5. Reproductive and developmental health risk from dioxin-like compounds: Insignificant risk from cement kilns burning waste-derived fuels

    SciTech Connect

    Holcomb, L.C.; Pedelty, J.F.

    1994-12-31

    Cement kilns burning waste-derived fuels emit low levels of dibenzodioxins and dibenzofurans and little or no PCB`s. Concern about possible effects on reproduction and development has prompted an evaluation of the research literature especially with regard to the reproductive and developmental effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In sufficient doses, dioxins, furans, and PCB can cause adverse health effects in some animals or humans. Calculated doses of TCDD-EQ (dioxin equivalents) are dependent on many assumptions, but where human effects have been demonstrated, doses were 100--1,000 times higher than the usual background environmental doses. This would include those environmental doses that would be received by the most-exposed individual living near cement kilns burning WDF. There is evidence to suggest that PCB`s have had an adverse impact on some wildlife although there is no evidence that these PCB`s are associated with cement kiln emissions. There is no evidence to suggest that dioxins, at environmental levels or associated with emissions from WDF-burning cement kilns, have caused adverse effects in either wildlife or humans. 63 refs., 3 tabs.

  6. GALAXIES IN X-RAY GROUPS. I. ROBUST MEMBERSHIP ASSIGNMENT AND THE IMPACT OF GROUP ENVIRONMENTS ON QUENCHING

    SciTech Connect

    George, Matthew R.; Bundy, Kevin; Leauthaud, Alexie; Finoguenov, Alexis; Tinker, Jeremy; Lin, Yen-Ting; Mei, Simona; Kneib, Jean-Paul; Ilbert, Olivier; Aussel, Herve; Le Floc'h, Emeric; Behroozi, Peter S.; Busha, Michael T.; Capak, Peter; Coccato, Lodovico; Covone, Giovanni; Faure, Cecile; Fiorenza, Stephanie L.; and others

    2011-12-01

    Understanding the mechanisms that lead dense environments to host galaxies with redder colors, more spheroidal morphologies, and lower star formation rates than field populations remains an important problem. As most candidate processes ultimately depend on host halo mass, accurate characterizations of the local environment, ideally tied to halo mass estimates and spanning a range in halo mass and redshift, are needed. In this work, we present and test a rigorous, probabilistic method for assigning galaxies to groups based on precise photometric redshifts and X-ray-selected groups drawn from the COSMOS field. The groups have masses in the range 10{sup 13} {approx}< M{sub 200c}/M{sub Sun} {approx}< 10{sup 14} and span redshifts 0 < z < 1. We characterize our selection algorithm via tests on spectroscopic subsamples, including new data obtained at the Very Large Telescope, and by applying our method to detailed mock catalogs. We find that our group member galaxy sample has a purity of 84% and completeness of 92% within 0.5 R{sub 200c}. We measure the impact of uncertainties in redshifts and group centering on the quality of the member selection with simulations based on current data as well as future imaging and spectroscopic surveys. As a first application of our new group member catalog which will be made publicly available, we show that member galaxies exhibit a higher quenched fraction compared to the field at fixed stellar mass out to z {approx} 1, indicating a significant relationship between star formation and environment at group scales. We also address the suggestion that dusty star-forming galaxies in such groups may impact the high-l power spectrum of the cosmic microwave background and find that such a population cannot explain the low power seen in recent Sunyaev-Zel'dovich measurements.

  7. U.S. Footage Drilled for Crude Oil Exploratory and Developmental Wells

    Gasoline and Diesel Fuel Update

    (Thousand Feet) and Developmental Wells (Thousand Feet) U.S. Footage Drilled for Crude Oil Exploratory and Developmental Wells (Thousand Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 79,428 1950's 92,695 95,106 98,148 102,136 113,362 121,148 120,352 110,043 93,105 94,611 1960's 86,568 85,626 88,431 81,809 80,463 73,322 67,340 58,634 59,517 61,582 1970's 56,859 49,109 49,269 44,416 52,025 66,819 68,892 75,451 77,041 82,688 1980's 125,262 172,167

  8. U.S. Footage Drilled for Crude Oil, Natural Gas, and Dry Developmental

    Gasoline and Diesel Fuel Update

    Wells (Thousand Feet) Developmental Wells (Thousand Feet) U.S. Footage Drilled for Crude Oil, Natural Gas, and Dry Developmental Wells (Thousand Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 100,821 1950's 117,183 122,802 128,518 133,581 148,408 156,976 158,943 147,864 131,820 137,441 1960's 136,345 135,191 141,018 129,164 131,923 125,678 107,215 93,518 94,012 99,642 1970's 95,026 85,358 92,875 92,605 102,059 125,817 133,365 157,917 173,472 181,702

  9. U.S. Footage Drilled for Dry Exploratory and Developmental Wells (Thousand

    Gasoline and Diesel Fuel Update

    Feet) and Developmental Wells (Thousand Feet) U.S. Footage Drilled for Dry Exploratory and Developmental Wells (Thousand Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 43,754 1950's 50,977 63,093 70,730 73,862 75,790 85,103 90,190 83,167 74,643 79,476 1960's 77,361 74,716 77,253 76,307 81,360 76,629 69,636 61,142 64,737 71,364 1970's 58,074 54,685 58,556 55,761 62,899 69,220 68,977 76,728 85,788 81,642 1980's 99,575 134,934 123,746 105,222 119,860

  10. U.S. Footage Drilled for Natural Gas Exploratory and Developmental Wells

    Gasoline and Diesel Fuel Update

    (Thousand Feet) and Developmental Wells (Thousand Feet) U.S. Footage Drilled for Natural Gas Exploratory and Developmental Wells (Thousand Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 12,437 1950's 13,685 13,947 15,257 18,248 18,857 19,930 22,738 23,836 25,555 26,606 1960's 28,246 29,292 28,949 24,533 25,598 24,931 25,948 21,581 20,716 24,162 1970's 23,623 23,460 30,006 38,045 38,449 44,454 49,113 63,686 75,841 80,468 1980's 92,106 108,353 107,149

  11. Advancing Usability Evaluation through Human Reliability Analysis

    SciTech Connect

    Ronald L. Boring; David I. Gertman

    2005-07-01

    This paper introduces a novel augmentation to the current heuristic usability evaluation methodology. The SPAR-H human reliability analysis method was developed for categorizing human performance in nuclear power plants. Despite the specialized use of SPAR-H for safety critical scenarios, the method also holds promise for use in commercial off-the-shelf software usability evaluations. The SPAR-H method shares task analysis underpinnings with human-computer interaction, and it can be easily adapted to incorporate usability heuristics as performance shaping factors. By assigning probabilistic modifiers to heuristics, it is possible to arrive at the usability error probability (UEP). This UEP is not a literal probability of error but nonetheless provides a quantitative basis to heuristic evaluation. When combined with a consequence matrix for usability errors, this method affords ready prioritization of usability issues.

  12. Taurine protects methamphetamine-induced developmental angiogenesis defect through antioxidant mechanism

    SciTech Connect

    Shao, Xue; Hu, Zhengtao; Hu, Chunyan; Bu, Qian; Yan, Guangyan; Deng, Pengchi; Lv, Lei; Wu, Dan; Deng, Yi; Zhao, Jinxuan; Zhu, Ruiming; Li, Yan; Li, Hongyu; Xu, Youzhi; Yang, Hanshuo; Zhao, Yinglan; Cen, Xiaobo

    2012-05-01

    Investigations have characterized addictive drug-induced developmental cardiovascular malformation in human, non-human primate and rodent. However, the underlying mechanism of malformation caused by drugs during pregnancy is still largely unknown, and preventive and therapeutic measures have been lacking. Using {sup 1}H NMR spectroscopy, we profiled the metabolites from human embryo endothelial cells exposed to methamphetamine (METH) and quantified a total of 226 peaks. We identified 11 metabolites modified robustly and found that taurine markedly increased. We then validated the hypothesis that this dramatic increase in taurine could attribute to its effect in inhibiting METH-induced developmental angiogenesis defect. Taurine supplement showed a more significant potential than other metabolites in protecting against METH-induced injury in endothelial cells. Taurine strongly attenuated METH-induced inhibition of proliferation and migration in endothelial cells. Furthermore, death rate and vessel abnormality of zebrafish embryos treated with METH were greatly reversed by taurine. In addition, taurine supplement caused a rapid decrease in reactive oxygen species generation and strongly attenuated the excitable arise of antioxidase activities in the beginning of METH exposure prophase. Dysregulations of NF-κB, p-ERK as well as Bax, which reflect apoptosis, cell cycle arrest and oxidative stress in vascular endothelium, were blocked by taurine. Our results provide the first evidence that taurine prevents METH-caused developmental angiogenesis defect through antioxidant mechanism. Taurine could serve as a potential therapeutic or preventive intervention of developmental vascular malformation for the pregnant women with drug use. Highlights: ► Metabonomics findings. ► Abnormal development. ► Dysregulations of key proteins.

  13. Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS

    SciTech Connect

    Shi Xiongjie; Du Yongbing; Lam, Paul K.S.; Wu, Rudolf S.S.; Zhou Bingsheng

    2008-07-01

    Perfluorooctanesulfonate (PFOS) is a persistent organic pollutant, the potential toxicity of which is causing great concern. In the present study, we employed zebrafish embryos to investigate the developmental toxicity of this compound. Four-hour post-fertilization (hpf) zebrafish embryos were exposed to 0.1, 0.5, 1, 3 and 5 mg/L PFOS. Hatching was delayed and hatching rates as well as larval survivorship were significantly reduced after the embryos were exposed to 1, 3 and 5 mg/L PFOS until 132 hpf. The fry displayed gross developmental malformations, including epiboly deformities, hypopigmentation, yolk sac edema, tail and heart malformations and spinal curvature upon exposure to PFOS concentrations of 1 mg/L or greater. Growth (body length) was significantly reduced in the 3 and 5 mg/L PFOS-treated groups. To test whether developmental malformation was mediated via apoptosis, flow cytometry analysis of DNA content, acridine orange staining and TUNEL assay was used. These techniques indicated that more apoptotic cells were present in the PFOS-treated embryos than in the control embryos. Certain genes related to cell apoptosis, p53 and Bax, were both significantly up-regulated upon exposure to all the concentrations tested. In addition, we investigated the effects of PFOS on marker genes related to early thyroid development (hhex and pax8) and genes regulating the balance of androgens and estrogens (cyp19a and cyp19b). For thyroid development, the expression of hhex was significantly up-regulated at all concentrations tested, whereas pax8 expression was significantly up-regulated only upon exposure to lower concentrations of PFOS (0.1, 0.5, 1 mg/L). The expression of cyp19a and of cyp19b was significantly down-regulated at all exposure concentrations. The overall results indicated that zebrafish embryos constitute a reliable model for testing the developmental toxicity of PFOS, and the gene expression patterns in the embryos were able to reveal some potential

  14. Relative risk site evaluations for Yakima Training Center

    SciTech Connect

    Smith, R.M.; Whelan, G.

    1996-11-01

    All 20 U.S. Army Yakima Training Center (YTC) sites evaluated were given a `low` relative risk. At Solid Waste Management Unit (SWMU) 22, a `minimum` soils contaminant hazard factor was assigned even though 6,700 mg/kg TPH-diesel was found in surface soil. SWMU 22 is physically located on top of and with the fence surrounding Area of Concern (AOC) 4. Because the diesel is most likely associated with AOC 4, and plans are to clean up AOC 4, any further actions regarding these contaminated soils should be addressed as part of the planned actions for AOC 4. Contaminant hazard factors of `moderate` were assigned to the soil pathway for SWMUs 4 and 7 because dieldrin and arsenic, respectively, were found in surface soil samples at concentrations exceeding standards. A `moderate` contaminant hazard factor was also assigned to the sediment pathway for AOC 1 because arsenic detected in sediments in `Larry`s Swimming Pool` exceeded the standard. All other contaminant hazard factors were rated as minimal. The receptor factor for all sites and pathways was rated `limited,` except for SWMU 54 in which the groundwater receptor factor was rated `potential.` A `potential` rating was assigned to the groundwater pathway at this site to be conservative. The site is located on the south side of the syncline axis where the unconfined aquifer may be present and there are no monitoring wells at the site to confirm or deny the presence of groundwater contamination.

  15. Eliminating livelock by assigning the same priority state to each message that is inputted into a flushable routing system during N time intervals

    DOEpatents

    Faber, Vance

    1994-01-01

    Livelock-free message routing is provided in a network of interconnected nodes that is flushable in time T. An input message processor generates sequences of at least N time intervals, each of duration T. An input register provides for receiving and holding each input message, where the message is assigned a priority state p during an nth one of the N time intervals. At each of the network nodes a message processor reads the assigned priority state and awards priority to messages with priority state (p-1) during an nth time interval and to messages with priority state p during an (n+1) th time interval. The messages that are awarded priority are output on an output path toward the addressed output message processor. Thus, no message remains in the network for a time longer than T.

  16. Eliminating livelock by assigning the same priority state to each message that is input into a flushable routing system during N time intervals

    DOEpatents

    Faber, V.

    1994-11-29

    Livelock-free message routing is provided in a network of interconnected nodes that is flushable in time T. An input message processor generates sequences of at least N time intervals, each of duration T. An input register provides for receiving and holding each input message, where the message is assigned a priority state p during an nth one of the N time intervals. At each of the network nodes a message processor reads the assigned priority state and awards priority to messages with priority state (p-1) during an nth time interval and to messages with priority state p during an (n+1) th time interval. The messages that are awarded priority are output on an output path toward the addressed output message processor. Thus, no message remains in the network for a time longer than T. 4 figures.

  17. American Evaluation Association Guiding Principles for Evaluators...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Five principles developed by American Evaluation Associ intended to guide professional practice of evaluators & to inform evaluation clients and the general public about principles ...

  18. The high current, fast, 100ns, Linear Transformer Driver (LTD) developmental project at Sandia Laboratories and HCEI.

    SciTech Connect

    Ward, Kevin S.; Long, Finis W.; Sinebryukhov, Vadim A. , Tomsk, Russia); Kim, Alexandre A. , Tomsk, Russia); Wakeland, Peter Eric; McKee, G. Randall; Woodworth, Joseph Ray; McDaniel, Dillon Heirman; Fowler, William E.; Mazarakis, Michael Gerrassimos; Porter, John Larry, Jr.; Struve, Kenneth William; Savage, Mark Edward; Stygar, William A.; LeChien, Keith R.; Matzen, Maurice Keith

    2010-09-01

    Sandia National Laboratories, Albuquerque, N.M., USA, in collaboration with the High Current Electronic Institute (HCEI), Tomsk, Russia, is developing a new paradigm in pulsed power technology: the Linear Transformer Driver (LTD) technology. This technological approach can provide very compact devices that can deliver very fast high current and high voltage pulses straight out of the cavity with out any complicated pulse forming and pulse compression network. Through multistage inductively insulated voltage adders, the output pulse, increased in voltage amplitude, can be applied directly to the load. The load may be a vacuum electron diode, a z-pinch wire array, a gas puff, a liner, an isentropic compression load (ICE) to study material behavior under very high magnetic fields, or a fusion energy (IFE) target. This is because the output pulse rise time and width can be easily tailored to the specific application needs. In this paper we briefly summarize the developmental work done in Sandia and HCEI during the last few years, and describe our new MYKONOS Sandia High Current LTD Laboratory. An extensive evaluation of the LTD technology is being performed at SNL and the High Current Electronic Institute (HCEI) in Tomsk Russia. Two types of High Current LTD cavities (LTD I-II, and 1-MA LTD) were constructed and tested individually and in a voltage adder configuration (1-MA cavity only). All cavities performed remarkably well and the experimental results are in full agreement with analytical and numerical calculation predictions. A two-cavity voltage adder is been assembled and currently undergoes evaluation. This is the first step towards the completion of the 10-cavity, 1-TW module. This MYKONOS voltage adder will be the first ever IVA built with a transmission line insulated with deionized water. The LTD II cavity renamed LTD III will serve as a test bed for evaluating a number of different types of switches, resistors, alternative capacitor configurations, cores

  19. SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Form documents modifications and changes to approved assignments and courses. SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) (100.74 KB) More Documents & Publications SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Candidate Developmental Assignment Evaluation SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT

  20. Ligand-specific transcriptional mechanisms underlie aryl hydrocarbon receptor-mediated developmental toxicity of oxygenated PAHs

    SciTech Connect

    Goodale, B. C.; La Du, J.; Tilton, S. C.; Sullivan, C. M.; Bisson, W. H.; Waters, K. M.; Tanguay, R. L.

    2015-07-03

    Polycyclic aromatic hydrocarbons (PAHs) are priority environmental contaminants that exhibit mutagenic, carcinogenic, proinflammatory, and teratogenic properties. Oxygen-substituted PAHs (OPAHs) are formed during combustion processes and via phototoxidation and biological degradation of parent (unsubstituted) PAHs. Despite their prevalence both in contaminated industrial sites and in urban air, OPAH mechanisms of action in biological systems are relatively understudied. Like parent PAHs, OPAHs exert structure-dependent mutagenic activities and activation of the aryl hydrocarbon receptor (AHR) and cytochrome p450 metabolic pathway. Four-ring OPAHs 1,9-benz-10-anthrone (BEZO) and benz(a)anthracene-7,12-dione (7,12-B[a]AQ) cause morphological aberrations and induce markers of oxidative stress in developing zebrafish with similar potency, but only 7,12-B[a]AQ induces robust Cyp1a protein expression. We investigated the role of the AHR in mediating the toxicity of BEZO and 7,12-B[a]AQ, and found that knockdown of AHR2 rescued developmental effects caused by both compounds. Using RNA-seq and molecular docking, we identified transcriptional responses that precede developmental toxicity induced via differential interaction with AHR2. Redox-homeostasis genes were affected similarly by these OPAHs, while 7,12-B[a]AQ preferentially activated phase 1 metabolism and BEZO uniquely decreased visual system genes. Analysis of biological functions and upstream regulators suggests that BEZO is a weak AHR agonist, but interacts with other transcriptional regulators to cause developmental toxicity in an AHR-dependent manner. Furthermore, identifying ligand-dependent AHR interactions and signaling pathways is essential for understanding toxicity of this class of environmentally relevant compounds.

  1. Ligand-specific transcriptional mechanisms underlie aryl hydrocarbon receptor-mediated developmental toxicity of oxygenated PAHs

    DOE PAGES [OSTI]

    Goodale, B. C.; Geisel School of Medicine at Dartmouth, Hanover, NH; La Du, J.; Tilton, S. C.; Pacific Northwest National Lab.; Sullivan, C. M.; Bisson, W. H.; Waters, K. M.; Tanguay, R. L.

    2015-07-03

    Polycyclic aromatic hydrocarbons (PAHs) are priority environmental contaminants that exhibit mutagenic, carcinogenic, proinflammatory, and teratogenic properties. Oxygen-substituted PAHs (OPAHs) are formed during combustion processes and via phototoxidation and biological degradation of parent (unsubstituted) PAHs. Despite their prevalence both in contaminated industrial sites and in urban air, OPAH mechanisms of action in biological systems are relatively understudied. Like parent PAHs, OPAHs exert structure-dependent mutagenic activities and activation of the aryl hydrocarbon receptor (AHR) and cytochrome p450 metabolic pathway. Four-ring OPAHs 1,9-benz-10-anthrone (BEZO) and benz(a)anthracene-7,12-dione (7,12-B[a]AQ) cause morphological aberrations and induce markers of oxidative stress in developing zebrafish with similar potency, butmore » only 7,12-B[a]AQ induces robust Cyp1a protein expression. We investigated the role of the AHR in mediating the toxicity of BEZO and 7,12-B[a]AQ, and found that knockdown of AHR2 rescued developmental effects caused by both compounds. Using RNA-seq and molecular docking, we identified transcriptional responses that precede developmental toxicity induced via differential interaction with AHR2. Redox-homeostasis genes were affected similarly by these OPAHs, while 7,12-B[a]AQ preferentially activated phase 1 metabolism and BEZO uniquely decreased visual system genes. Analysis of biological functions and upstream regulators suggests that BEZO is a weak AHR agonist, but interacts with other transcriptional regulators to cause developmental toxicity in an AHR-dependent manner. Furthermore, identifying ligand-dependent AHR interactions and signaling pathways is essential for understanding toxicity of this class of environmentally relevant compounds.« less

  2. American Evaluation Association Guiding Principles for Evaluators

    SciTech Connect

    None

    2009-01-18

    Five principles developed by American Evaluation Associ intended to guide professional practice of evaluators & to inform evaluation clients and the general public about principles they can expect to be upheld by professional evaluators.

  3. Who's Evaluating What? Planned Program Evaluations

    Energy.gov [DOE]

    Better Buildings Peer Exchange Call, Who's Evaluating What? Planned Program Evaluations, November 17, 2011. During this call participants shared their evaluation plans and initial results and discussed DOE and fellow programs' evaluation efforts.

  4. Recent experimental results from a long-pulse J-band relativistic klystron amplifier developmental effort

    SciTech Connect

    Kato, K.G.; Crouch, D.D.; Sar, D.R.; Speciale, R.A.; Carlsten, B.E.; Fazio, M.V.; Haynes, W.B.; Stringfield, R.M.

    1994-12-31

    Recent experimental results, supporting simulations, and design modeling are presented from a developmental effort to a produce a long pulse ({approximately}1{mu}s) J-band (5.85-8.2 GHz) relativistic klystron amplifier (RKA) of the high current NRL genealogy. This RKA is designed to operate at approximately 6.6 GHz, with a desired RF output {approximately}700 MW. Conversion of electron beam energy to microwave energy is obtained by a mock magnetically insulated coaxial converter which, in various incarnations, can be made to be either a cavity gap extractor or an inverse cathode.

  5. Proximal trisomy 1q in a girl with developmental delay and minor anomalies

    SciTech Connect

    Furforo, L. |; Rittler, M.; Slavutsky, I.R.

    1996-09-06

    We report on a girl with developmental delay, macrocephaly, facial asymmetry, small downturned palpebral fissures, high and narrow palate, micrognathia, short neck, a heart defect, and unilateral renal agenesis. Cytogenetic analysis showed a proximal tandem duplication of the long arm of chromosome one (1q12{r_arrow}q21.3). This abnormality was suggested by G-and C-banding but it was specifically characterized by fluorescent in situ hybridization (FISH). Clinical findings in our patient are compared with those of the literature in an attempt to delineate the phenotype in patients with proximal 1q duplication. 12 refs., 4 figs., 1 tab.

  6. RELAP5/MOD2 Overview and Developmental. Assessment Results from TMl-1 Plant Transient Analysis

    SciTech Connect

    Lin, J. C.; Tsai, C. C.; Ransom, V. H.; Johnsen, G. W.

    2013-02-01

    RELAP5/MOD2 is a new version of the RELAP5 thermal-hydraulic computer code containing improved modeling features that provide a generic capability for pressurized water reactor transient simulation. The objective of this paper is to provide code users with an overview of the code and to report developmental assessment results obtained from a Three Mile Island Unit One plant transient analysis. The assessment shows that the injection of highly sub-cooled water into a high-pressure primary coolant system does not cause unphysical results or pose a problem for RELAP5/MOD2. (author)

  7. RELAP5/MOD2 overview and developmental assessment results from TMI-1 plant transient analysis

    SciTech Connect

    Lin, J.C.; Tsai, C.C.; Ransom, V.H.; Johnsen, G.W.

    1984-01-01

    RELAP5/MOD2 is a new version of the RELAP5 thermal-hydraulic computer code containing improved modeling features that provide a generic capability for pressurized water reactor transient simulation. Objective of this paper is to provide code users with an overview of the code and to report developmental assessment results obtained from a Three Mile Island Unit One plant transient analysis. The assessment shows that the injection of highly subcooled water into a high-pressure primary coolant system does not cause unphysical results or pose a problem for RELAP5/MOD2.

  8. Sub-microradian Surface Slope Metrology with the ALS Developmental Long Trace Profiler

    SciTech Connect

    Yashchuk, Valeriy V; Barber, Samuel; Domning, Edward E.; Kirschman, Jonathan L.; Morrison, Gregory Y.; Smith, Brian V; Siewert, Frank; Zeschke, Thomas; Geckeler, Ralf; Just, Andreas

    2009-09-11

    A new low budget slope measuring instrument, the Developmental Long Trace Profiler (DLTP), was recently brought to operation at the ALS Optical Metrology Laboratory. The design, instrumental control and data acquisition system, initial alignment and calibration procedures, as well as the developed experimental precautions and procedures are described in detail. The capability of the DLTP to achieve sub-microradian surface slope metrology is verified via cross-comparison measurements with other high performance slope measuring instruments when measuring the same high quality test optics. The directions of future work to develop a surface slope measuring profiler with nano-radian performance are also discussed.

  9. U.S. Average Depth of Crude Oil Exploratory and Developmental Wells Drilled

    Gasoline and Diesel Fuel Update

    (Feet per Well) and Developmental Wells Drilled (Feet per Well) U.S. Average Depth of Crude Oil Exploratory and Developmental Wells Drilled (Feet per Well) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 3,720 1950's 3,893 4,103 4,214 4,033 4,028 3,981 3,942 4,021 3,916 3,935 1960's 3,889 3,994 4,070 4,063 4,042 4,059 4,013 3,825 4,153 4,286 1970's 4,385 4,126 4,330 4,369 3,812 3,943 3,895 4,025 4,017 3,966 1980's 3,801 3,923 3,793 3,662 3,791 3,906 3,999

  10. U.S. Average Depth of Crude Oil, Natural Gas, and Dry Developmental Wells

    Gasoline and Diesel Fuel Update

    Drilled (Feet per Well) Developmental Wells Drilled (Feet per Well) U.S. Average Depth of Crude Oil, Natural Gas, and Dry Developmental Wells Drilled (Feet per Well) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 3,568 1950's 3,691 3,851 3,999 3,880 3,905 3,904 3,880 3,966 3,907 3,999 1960's 4,020 4,064 4,227 4,193 4,179 4,288 4,112 4,004 4,328 4,431 1970's 4,610 4,480 4,590 4,687 4,249 4,285 4,214 4,404 4,421 4,374 1980's 4,166 4,209 4,225 4,004 4,125

  11. U.S. Average Depth of Dry Exploratory and Developmental Wells Drilled (Feet

    Gasoline and Diesel Fuel Update

    per Well) Exploratory and Developmental Wells Drilled (Feet per Well) U.S. Average Depth of Dry Exploratory and Developmental Wells Drilled (Feet per Well) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 3,473 1950's 3,445 3,706 3,983 4,004 4,004 4,161 4,079 4,126 4,110 4,275 1960's 4,248 4,311 4,524 4,552 4,598 4,723 4,573 4,616 5,053 5,195 1970's 5,265 5,305 5,377 5,403 5,191 5,073 5,014 5,120 5,183 5,071 1980's 4,791 4,827 4,691 4,320 4,631 4,733 4,763

  12. U.S. Average Depth of Dry Holes Developmental Wells Drilled (Feet per Well)

    Gasoline and Diesel Fuel Update

    Developmental Wells Drilled (Feet per Well) U.S. Average Depth of Dry Holes Developmental Wells Drilled (Feet per Well) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 3,225 1950's 3,077 3,255 3,520 3,401 3,512 3,699 3,574 3,605 3,631 3,844 1960's 3,889 3,782 4,239 4,143 4,207 4,446 3,900 3,901 4,311 4,437 1970's 4,714 4,633 4,725 4,851 4,599 4,415 4,439 4,662 4,600 4,517 1980's 4,214 4,226 4,184 3,974 4,205 4,306 4,236 4,390 4,704 4,684 1990's 4,755 4,629

  13. U.S. Average Depth of Natural Gas Developmental Wells Drilled (Feet per

    Gasoline and Diesel Fuel Update

    Well) Developmental Wells Drilled (Feet per Well) U.S. Average Depth of Natural Gas Developmental Wells Drilled (Feet per Well) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 3,412 1950's 3,766 3,837 4,015 4,373 4,365 4,339 4,734 4,950 4,801 5,120 1960's 5,321 5,145 5,186 5,198 5,171 5,337 5,474 5,629 5,716 5,531 1970's 5,644 5,670 5,259 5,286 5,173 5,238 4,960 5,053 5,066 5,082 1980's 5,093 5,149 5,453 5,187 5,158 5,193 5,080 5,112 5,155 5,038 1990's

  14. U.S. Average Depth of Natural Gas Exploratory and Developmental Wells

    Gasoline and Diesel Fuel Update

    Drilled (Feet per Well) and Developmental Wells Drilled (Feet per Well) U.S. Average Depth of Natural Gas Exploratory and Developmental Wells Drilled (Feet per Well) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 3,698 1950's 3,979 4,056 4,342 4,599 4,670 4,672 5,018 5,326 5,106 5,396 1960's 5,486 5,339 5,408 5,368 5,453 5,562 5,928 5,898 5,994 5,918 1970's 5,860 5,890 5,516 5,488 5,387 5,470 5,220 5,254 5,262 5,275 1980's 5,275 5,351 5,617 5,319 5,276

  15. U.S. Footage Drilled for Dry Developmental Wells (Thousand Feet)

    Gasoline and Diesel Fuel Update

    Developmental Wells (Thousand Feet) U.S. Footage Drilled for Dry Developmental Wells (Thousand Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 17,315 1950's 20,020 24,370 26,999 26,582 29,998 31,883 32,143 29,747 27,343 30,800 1960's 33,826 31,423 35,030 33,460 36,782 36,548 26,552 22,960 23,162 25,446 1970's 22,951 20,186 22,475 21,190 24,296 28,772 31,008 35,905 39,493 39,130 1980's 49,326 65,720 63,066 56,233 61,236 52,784 30,636 26,842 25,438 20,152

  16. U.S. Footage Drilled for Natural Gas Developmental Wells (Thousand Feet)

    Gasoline and Diesel Fuel Update

    Developmental Wells (Thousand Feet) U.S. Footage Drilled for Natural Gas Developmental Wells (Thousand Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1940's 10,028 1950's 11,329 11,451 11,863 14,296 14,458 14,718 17,559 17,869 20,083 20,575 1960's 22,780 24,042 23,762 20,303 21,394 21,174 20,140 17,602 16,975 19,177 1970's 19,945 19,850 25,159 31,007 30,766 36,032 39,992 53,431 64,043 67,825 1980's 78,244 91,274 92,386 67,844 81,545 68,149 39,638 37,520 40,371

  17. Inhalation developmental toxicology studies: Teratology study of tetrahydrofuran in mice and rats: Final report

    SciTech Connect

    Mast, T.J.; Evanoff, J.J.; Stoney, K.H.; Westerberg, R.B.; Rommereim, R.L.; Weigel, R.J.

    1988-08-01

    Tetrahydrofuran (THF), a four-carbon cyclic ether, is widely used as an industrial solvent. Although it has been used in large quantities for many years, few long-term toxicology studies, and no reproductive or developmental studies, have been conducted on THF. This study addresses the potential for THF to cause developmental toxicity in rodents by exposing Sprague-Dawley rats and Swiss (CD-1) mice to 0, 600, 1800, or 5000 ppm tetrahydrofuran (THF) vapors, 6 h/day, 7 dy/wk. Each treatment group consisted of 10 virgin females (for comparison), and approx.33 positively mated rats or mice. Positively mated mice were exposed on days 6--17 of gestation (dg), and rats on 6--19 dg. The day of plug or sperm detection was designated as O dg. Body weights were obtained throughout the study period, and uterine and fetal body weights were obtained at sacrifice (rats, 20 dg; mice, 18 dg). Implants were enumerated and their status recorded and live fetuses were examined for gross, visceral, skeletal, and soft-tissue craniofacial defects. 27 refs., 6 figs., 23 tabs.

  18. Mineral evaluation of part of the Gold Butte district, Clark County, Nevada. National Uranium Resource Evaluation

    SciTech Connect

    Dexter, J.J.; Goodknight, C.S.; Dayvault, R.D.; Dickson, R.E.

    1983-03-01

    The mineral potential of part of the Gold Butte district, Clark County, Nevada, was investigated to supplement the evaluation of granitic rocks in the area as a probable geologic environment for uranium mineralization. This project is a part of the National Uranium Resource Evaluation (NURE) program conducted by Bendix Field Engineering Corporation for the US Department of Energy. A total of 41 stream-sediment samples and 149 rock samples were collected; the stream-sediment samples were analyzed chemically, and most f the rock samples were analyzed chemically and petrographically. The project area was restricted to Precambrian rocks, which comprise a metamorphic complex of early Proterozoic age, charnockitic rocks of early or middle Proterozoic age and ultramafic rocks and the Gold Butte Granite of middle Proterozoic age. Although the project area is not favorable for uranium deposits according to NURE criteria, an area of low resource potential for uranium, thorium, rare-earth elements and yttrium, and niobium-tantalum was assigned to the contact zone of the Gold Butte Granite. Pegmatites and aplites in the zone contain high concentrations of these elements. Two areas of moderate potential for gold and silver in quartz veins are within the project area; small-scale operations may recover these elements profitably. Titanium has a low-to-moderate resource potential, although the deposits are currently subeconomic. The titanium concentrations occur as titaniferous magnetite- and ilmenite-bearing placer sands. One small area has been assigned a low-to-moderate resource potential for vermiculite in altered ultramafic rocks. Tungsten has been assigned a low resource potential in two places within the project area; scheelite-bearing ultramafic bodies are small and scattered. Platinum-group metals and copper have no resource potential in the project area.

  19. Gene expression profiles in the cerebellum and hippocampus following exposure to a neurotoxicant, Aroclor 1254: Developmental effects

    SciTech Connect

    Royland, Joyce E.; Wu, Jinfang; Zawia, Nasser H.; Kodavanti, Prasada Rao S.

    2008-09-01

    The developmental consequences of exposure to the polychlorinated biphenyls (PCBs) have been widely studied, making PCBs a unique model to understand issues related to environmental mixture of persistent chemicals. PCB exposure in humans adversely affects neurocognitive development, causes psychomotor difficulties, and contributes to attention deficits in children, all of which seem to be associated with altered patterns of neuronal connectivity. In the present study, we examined gene expression profiles in the rat nervous system following PCB developmental exposure. Pregnant rats (Long-Evans) were dosed perinatally with 0 or 6 mg/kg/day of Aroclor 1254 from gestation day 6 through postnatal day (PND) 21. Gene expression in cerebellum and hippocampus from PND7 and PND14 animals was analyzed with an emphasis on developmental aspects. Changes in gene expression ({>=} 1.5 fold) in control animals identified normal developmental changes. These basal levels of expression were compared to data from Aroclor 1254-treated animals to determine the impact of gestational PCB exposure on developmental parameters. The results indicate that the expression of a number of developmental genes related to cell cycle, synaptic function, cell maintenance, and neurogenesis is significantly altered from PND7 to PND14. Aroclor 1254 treatment appears to dampen the overall growth-related gene expression levels in both regions with the effect being more pronounced in the cerebellum. Functional analysis suggests that Aroclor 1254 delays maturation of the developing nervous system, with the consequences dependent on the ontological state of the brain area and the functional role of the individual gene. Such changes may underlie learning and memory deficits observed in PCB exposed animals and humans.

  20. Final report on the developmental toxicity of ethylenediamine (CAS No. 107-15-3) in New Zealand white rabbits. Report for November-February 1992

    SciTech Connect

    Not Available

    1993-03-01

    Ethylenediamine (EDA) is a major industrial chemical with an estimated U.S. production of 64 million pounds in 1985. EDA is used as a chemical intermediate or solvent in manufacturing, as a paint thinner, and as a constituent of certain cosmetic, pharmaceutical and veterinary products. Based upon its widespread applications and the potential for exposure in pregnant women, EDA was evaluated for maternal and developmental toxicity using a laboratory animal model. Artificially-inseminated New Zealand White rabbits (26/group) were administered ethylenediamine (0, 10, 40 or 80 mg/kg/day) by gavage on gestational days (gd) 6 through 19. The doses administered were equivalent to 0, 22, 89 or 178 of EDA.2HC1. Maternal clinical signs, body weight, and food consumption were monitored at regular intervals throughout gestation. At termination (gd 30), the uterus was removed and examined to determine pregnancy status and to evaluate the number of resorptions, and dead or live fetuses. Dead or live fetuses were weighed, and live fetuses examined for external, visceral and skeletal defects.

  1. RTAP evaluation

    SciTech Connect

    Cupps, K.; Elko, S.; Folta, P.

    1995-01-23

    An in-depth analysis of the RTAP product was undertaken within the CNC associate program to determine the feasibility of utilizing it to replace the current Supervisory Control System that supports the AVLIS program. This document contains the results of that evaluation. With some fundamental redesign the current Supervisory Control system could meet the needs described above. The redesign would require a large amount of software rewriting and would be very time consuming. The higher level functionality (alarming, automation, etc.) would have to wait until its completion. Our current understanding and preliminary testing indicate that using commercial software is the best way to get these new features at the minimum cost to the program. Additional savings will be obtained by moving the maintenance costs of the basic control system from in-house to commercial industry and allowing our developers to concentrate on the unique control areas that require customization. Our current operating system, VMS, has become a hindrance. The UNIX operating system has become the choice for most scientific and engineering systems and we should follow suit. As a result of the commercial system survey referenced above we selected RTAP, a SCADA product developed by Hewlett Packard (HP), as the most favorable product to replace the current supervisory system in AVLIS. It is an extremely open system, with a large, well defined Application Programming Interface (API). This will allow the seamless integration of unique front end devices in the laser area (e.g. Optical Device Controller). RTAP also possesses various functionality that is lacking in our current system: integrated alarming, real-time configurable database, system scalability, and a Sequence Control Language (SQL developed by CPU, an RTAP Channel Partner) that will facilitate the automation necessary to bring the AVLIS process to plant-line operation. It runs on HP-9000, DEC-Alpha, IBM-RS6000 and Sun Workstations.

  2. Full differentiation and assignment of boron species in the electrolytes Li{sub 2}B{sub 6}O{sub 9}F{sub 2} and Li{sub 2}B{sub 3}O{sub 4}F{sub 3} by solid-state {sup 11}B NMR spectroscopy

    SciTech Connect

    Braeuniger, Thomas; Pilz, Thomas; Chandran, C. Vinod; Jansen, Martin

    2012-10-15

    The syntheses of two new fluorooxoborates, Li{sub 2}B{sub 3}O{sub 4}F{sub 3} and Li{sub 2}B{sub 6}O{sub 9}F{sub 2}, which possess considerable ion conductivity at higher temperatures, have been reported recently. Here, we describe the characterisation of these compounds by solid-state {sup 11}B NMR spectroscopy. The complex central-transition MAS spectra, resulting from overlap of sub-spectra contributed by the individual boron species in the crystal structures, could be clearly separated by acquisition and analysis of 3QMAS spectra. By numerical fit of these sub-spectra, the isotropic chemical shift {delta}{sub iso}, the quadrupolar coupling constant {chi}, and the asymmetry {eta} were determined. Using known relations between boron coordination and chemical shift as well as quadrupolar coupling, the individual {sup 11}B NMR resonances have been ascribed to boron species in tetrahedral or trigonal environment. To remove remaining assignment ambiguities, the response of the {sup 11}B resonances to {sup 19}F decoupling was qualitatively analysed. Thus, by using the combined information conveyed by chemical shift, quadrupolar and dipolar interaction, a complete assignment of the complex {sup 11}B line shapes exhibited by the fluorooxoborates has been achieved. - Graphical abstract: Structure and solid-state {sup 11}B NMR spectrum of Li{sub 2}B{sub 3}O{sub 4}F{sub 3}. Highlights: Black-Right-Pointing-Pointer Characterisation of title compounds by solid-state {sup 11}B NMR spectroscopy. Black-Right-Pointing-Pointer Sub-spectra of boron species separated by evaluation of 3QMAS spectra. Black-Right-Pointing-Pointer Isotropic chemical shift and quadrupolar interaction parameters determined. Black-Right-Pointing-Pointer Full boron assignment based on NMR parameters and response to {sup 19}F decoupling.

  3. Operation Greenhouse. Scientific Director's report of atomic weapon tests at Eniwetok, 1951. Annex 6. 6. Evaluation of filter material

    SciTech Connect

    Engquist, E,H.

    1985-04-01

    Four types of standard and developmental filter materials used in individual and collective-protective devices and one type of developmental filter material used for sampling of air for particulate matter were evaluated against the contamination produced by the detonation of an atomic bomb and present in the resulting radioactive cloud. These filter materials were evaluated in multilayer pads at the standard flow-rate conditions used by the Chemical Corps in evaluation studies of filter materials. This permitted correlation of results of laboratory data. Analysis of the materials was made by counting the gross beta activity collected on successive layers of the same filter material and the efficiency of the materials was calculated from the data obtained.

  4. NPR (New Production Reactor) capacity cost evaluation

    SciTech Connect

    1988-07-01

    The ORNL Cost Evaluation Technical Support Group (CETSG) has been assigned by DOE-HQ Defense Programs (DP) the task defining, obtaining, and evaluating the capital and life-cycle costs for each of the technology/proponent/site/revenue possibilities envisioned for the New Production Reactor (NPR). The first part of this exercise is largely one of accounting, since all NPR proponents use different accounting methodologies in preparing their costs. In order to address this problem of comparing ''apples and oranges,'' the proponent-provided costs must be partitioned into a framework suitable for all proponents and concepts. If this is done, major cost categories can then be compared between concepts and major cost differences identified. Since the technologies proposed for the NPR and its needed fuel and target support facilities vary considerably in level of technical and operational maturity, considerable care must be taken to evaluate the proponent-derived costs in an equitable manner. The use of cost-risk analysis along with derivation of single point or deterministic estimates allows one to take into account these very real differences in technical and operational maturity. Chapter 2 summarizes the results of this study in tabular and bar graph form. The remaining chapters discuss each generic reactor type as follows: Chapter 3, LWR concepts (SWR and WNP-1); Chapter 4, HWR concepts; Chapter 5, HTGR concept; and Chapter 6, LMR concept. Each of these chapters could be a stand-alone report. 39 refs., 36 figs., 115 tabs.

  5. Metallurgical evaluation of FMPC Vessel No. 2

    SciTech Connect

    Bagnall, C.; Wise, W.N.

    1989-03-01

    A major purpose of this evaluation program was to accumulate information on the behavior and properties of a vessel at the Feed Materials Production Center, fabricated of Monel 400, after service exposure in a UF/sub 6/--UF/sub 4/ reduction tower. These data will then be used to aid in the formulation of an equation to predict remaining life for the vessels. In addition, data from this destructive evaluation will provide information on the reliability of the reaction vessel surveillance program currently in operation at FMPC. After 1400 h of operation, Vessel No. 2 was removed from service and assigned to this program for extensive study. The report describes an initial survey of the physical condition of the vessel, provides details of the sampling plan, and then proceeds to document information in the various areas of investigation. These include radiography, chemical analysis, and mechanical properties over a temperature range up to 1800/degree/F. Metallographic studies from six key locations of the reaction vessel were conducted; major weld areas and selected tensile specimens were also examined. The report continues with a summary of the findings and a discussion of key aspects in relation to pertinent literature. The final section of the report provides conclusions drawn from evaluation of Vessel No. 2, and sets forth recommendations related to fabrication and extension of its operating life. 12 refs., 43 figs., 16 tabs.

  6. Overseas Assignments | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    This handbook covers all types of Federal employment overseas, including details, both within DOE as well as to other agencies; transfers to approved international organizations; ...

  7. Program Assignments | Department of Energy

    Energy Saver

    Balanced Scorecard Program Officer Contractual Services Budget Officer Headquarters Purchase Card Program Headquarters Contract Closeout Headquarters Data Mining Programs Strategic ...

  8. JOBAID-ASSIGNING DELEGATES (SUPERVISOR)

    Energy.gov [DOE]

    The purpose of this job aid is to guide you through the step-by-step process of isung the delegate feature within SuccessFactors Learning.

  9. Inhalation developmental toxicology studies: Teratology study of acetone in mice and rats: Final report

    SciTech Connect

    Mast, T.J.; Evanoff, J.J.; Rommereim, R.L.; Stoney, K.H.; Weigel, R.J.; Westerberg, R.B.

    1988-11-01

    Acetone, an aliphatic ketone, is a ubiquitous industrial solvent and chemical intermediate; consequently, the opportunity for human exposure is high. The potential for acetone to cause developmental toxicity was assessed in Sprague-Dawley rats exposed to 0, 440, 2200, or 11000 ppm, and in Swiss (CD-1) mice exposed to 0, 440, 2200, and 6600 ppm acetone vapors, 6 h/day, 7 days/week. Each of the four treatment groups consisted of 10 virgin females (for comparison), and approx.32 positively mated rats or mice. Positively mated mice were exposed on days 6-17 of gestation (dg), and rats on 6-19 dg. The day of plug or sperm detection was designated as 0 dg. Body weights were obtained throughout the study period, and uterine and fetal body weights were obtained at sacrifice (rats, 20 dg; mice, 18 dg). Implants were enumerated and their status recorded. Live fetuses were sexed and examined for gross, visceral, skeletal, and soft-tissue craniofacial defects. 46 refs., 6 figs., 27 tabs.

  10. Inhalation developmental toxicology studies: Teratology study of isoprene in mice and rats: Final report

    SciTech Connect

    Mast, T.J.; Evanoff, J.J.; Stoney, K.H.; Westerberg, R.B.; Rommereim, R.L.; Weigel, R.J.

    1989-01-01

    Isoprene, a reactive, branched diene, is used in large quantities in the manufacture of polyisoprene and as a copolymer in the synthesis of butyl rubber. The potential for isoprene to cause developmental toxicity was assessed in rodents, by exposing four groups each of Sprague-Dawley rats and Swiss (CD-1) mice to 0, 280, 1400, or 7000 ppM isoprene vapors, 6 h/day, 7 day/wk. Each treatment group consisted of 10 virgin females (for comparison), and approx.30 positively mated rats or mice. Positively mated mice were exposed on days 6-17 of gestation (dg), and rats on 6-19 dg. The day of plug or sperm detection was designated as 0 dg. Body weights were obtained throughout the study period, and uterine and fetal body weights were obtained at sacrifice (rats, 20 dg; mice, 18 dg). Implants were enumerated and their status recorded. Live fetuses were sexed and examined for gross, visceral, skeletal, and soft-tissue craniofacial defects. 31 refs., 6 figs., 19 tabs.

  11. A developmentally plastic adult mouse kidney cell line spontaneously generates multiple adult kidney structures

    SciTech Connect

    Webb, Carol F.; Ratliff, Michelle L.; Powell, Rebecca; Wirsig-Wiechmann, Celeste R.; Lakiza, Olga; Obara, Tomoko

    2015-08-07

    Despite exciting new possibilities for regenerative therapy posed by the ability to induce pluripotent stem cells, recapitulation of three-dimensional kidneys for repair or replacement has not been possible. ARID3a-deficient mouse tissues generated multipotent, developmentally plastic cells. Therefore, we assessed the adult mouse ARID3a−/− kidney cell line, KKPS5, which expresses renal progenitor surface markers as an alternative cell source for modeling kidney development. Remarkably, these cells spontaneously developed into multicellular nephron-like structures in vitro, and engrafted into immunocompromised medaka mesonephros, where they formed mouse nephron structures. These data implicate KKPS5 cells as a new model system for studying kidney development. - Highlights: • An ARID3a-deficient mouse kidney cell line expresses multiple progenitor markers. • This cell line spontaneously forms multiple nephron-like structures in vitro. • This cell line formed mouse kidney structures in immunocompromised medaka fish kidneys. • Our data identify a novel model system for studying kidney development.

  12. Transcriptomics-based identification of developmental toxicants through their interference with cardiomyocyte differentiation of embryonic stem cells

    SciTech Connect

    Dartel, Dorien A.M. van; Pennings, Jeroen L.A.; Schooten, Frederik J. van; Piersma, Aldert H.

    2010-03-15

    The embryonic stem cell test (EST) predicts developmental toxicity based on the inhibition of cardiomyocyte differentiation of embryonic stem cells (ESC). The subjective endpoint, the long culture duration together with the undefined applicability domain and related predictivity need further improvement to facilitate implementation of the EST into regulatory strategies. These aspects may be improved by studying gene expression changes in the ESC differentiation cultures and their modulation by compound exposure using transcriptomics. Here, we tested the developmental toxicants monobutyl phthalate and 6-aminonicotinamide. ESC were allowed to differentiated, and cardiomyocyte differentiation was assessed after 10 days of culture. RNA of solvent controls was collected after 0, 24, 48, 72 and 96 h of exposure, and RNA of developmental-toxicant-exposed cultures was collected after 24 and 96 h. Samples were hybridized to DNA microarrays, and 1355 genes were found differentially expressed among the unexposed experimental groups. These regulated genes were involved in differentiation-related processes, and Principal Component Analysis (PCA) based on these genes showed that the unexposed experimental groups appeared in chronological order in the PCA, which can therefore be regarded as a continuous representation of the differentiation track. The developmental-toxicant-exposed cultures appeared to deviate significantly from this differentiation track, which confirms the compound-modulating effects on the differentiation process. The incorporation of transcriptomics in the EST is expected to provide a more informative and improved endpoint in the EST as compared with morphology, allowing early detection of differentiation modulation. Furthermore, this approach may improve the definition of the applicability domain and predictivity of the EST.

  13. Evaluation Project 4492

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Organization area to allow the movement and radio-graphing of component for evaluation to determine the proper Project Execution Plan for dismantlement. Evaluation Project...

  14. sup 1 H and sup 31 P-NMR assignments of the non-exchangeable protons of the consensus acceptor exon:intron junction d(CpTpApCpApGpGpT)

    SciTech Connect

    Lown, J.W.; Chang, D.K.; Debart, F.; Rayner, B.; Imbach, J.L. )

    1986-06-01

    The consensus acceptor exon:intron junction d(CpTpApCpApGpGpT) has been synthesized by a modified phosphotriester method. The non-self complementary octamer exists in the single strand form in aqueous buffer at 20 degrees C as evidenced by temperature variable {sup 1}H-NMR and NOE measurements. The non-exchangeable proton assignments were secured using a combination of techniques including two-dimensional COSY, NOESY and the double quantum technique {sup 1}H-{sup 1}H-INADEQUATE as well as inversion recovery T1 experiments. The new technique of {sup 31}P-1H shift correlation is particularly valuable in removing certain ambiguities in the sugar proton assignments. Characteristic chemical shifts for the base protons which are determined by their immediate molecular environments are also useful in assignments. The consensus acceptor exon:intron junction adopts a random coil conformation in solution under the experimental conditions employed.

  15. Identification of a distinct type IV collagen. alpha. chain with restricted kidney distribution and assignment of its gene to the locus of X chromosome-linked Alport syndrome

    SciTech Connect

    Hostikka, S.L.; Hoeyhtyae, M.; Tryggvason, K. ); Eddy, R.L.; Byers, M.G.; Shows, T.B. )

    1990-02-01

    The authors have identified and extensively characterized a type IV collagen {alpha} chain, referred to as {alpha}5(IV). Four overlapping cDNA clones isolated contain an open reading frame for 543 amino acid residues of the carboxyl-terminal end of a collagenous domain, a 229-residue carboxyl-terminal noncollagenous domain, and 1201 base pairs coding for a 3{prime} untranslated region. The collagenous Gly-Xaa-Yaa repeat sequence has five imperfections that coincide with those in the corresponding region of the {alpha}1(IV) chain. The noncollagenous domain has 12 conserved cysteine residues and 83% and 63% sequence identity with the noncollagenous domains of the {alpha}1(IV) and {alpha}2(IV) chains, respectively. The {alpha}5(IV) chain has less sequence identity with the putative bovine {alpha}3(IV) and {alpha}4(IV) chains. Antiserum against an {alpha}5(IV) synthetic peptide stained a polypeptide chain of about 185 kDa by immunoblot analysis and immunolocalization of the chain in human kidney was almost completely restricted to the glomerulus. The gene was assigned to the Xq22 locus by somatic cell hybrids and in situ hybridization. This may be identical or close to the locus of the X chromosome-linked Alport syndrome that is believed to be a type IV collagen disease.

  16. Evaluation Consultant RFP

    Office of Energy Efficiency and Renewable Energy (EERE)

    Evaluation Consultant RFP, from the Tool Kit Framework: Small Town University Energy Program (STEP).

  17. Preliminary Impact Evaluation BBNP

    Energy.gov [DOE]

    Preliminary Impact Evaluation of the U.S. Department of Energy's Better Buildings Neighborhood Program, 2013.

  18. Linking Automated Data Analysis and Visualization with Applications in Developmental Biology and High-Energy Physics

    SciTech Connect

    Ruebel, Oliver

    2009-12-01

    Knowledge discovery from large and complex collections of today's scientific datasets is a challenging task. With the ability to measure and simulate more processes at increasingly finer spatial and temporal scales, the increasing number of data dimensions and data objects is presenting tremendous challenges for data analysis and effective data exploration methods and tools. Researchers are overwhelmed with data and standard tools are often insufficient to enable effective data analysis and knowledge discovery. The main objective of this thesis is to provide important new capabilities to accelerate scientific knowledge discovery form large, complex, and multivariate scientific data. The research covered in this thesis addresses these scientific challenges using a combination of scientific visualization, information visualization, automated data analysis, and other enabling technologies, such as efficient data management. The effectiveness of the proposed analysis methods is demonstrated via applications in two distinct scientific research fields, namely developmental biology and high-energy physics.Advances in microscopy, image analysis, and embryo registration enable for the first time measurement of gene expression at cellular resolution for entire organisms. Analysis of high-dimensional spatial gene expression datasets is a challenging task. By integrating data clustering and visualization, analysis of complex, time-varying, spatial gene expression patterns and their formation becomes possible. The analysis framework MATLAB and the visualization have been integrated, making advanced analysis tools accessible to biologist and enabling bioinformatic researchers to directly integrate their analysis with the visualization. Laser wakefield particle accelerators (LWFAs) promise to be a new compact source of high-energy particles and radiation, with wide applications ranging from medicine to physics. To gain insight into the complex physical processes of particle

  19. Evaluation of Potential Impacts of Microbial Activity on Drift Chemistry

    SciTech Connect

    Y. Wang

    2004-11-18

    ''Evaluation of Potential Impacts of Microbial Activity on Drift Chemistry'' focuses on the potential for microbial communities that could be active in repository emplacement drifts to influence the in-drift bulk chemical environment. This report feeds analyses to support the inclusion or exclusion of features, events, and processes (FEPs) in the total system performance assessment (TSPA) for the license application (LA), but this work is not expected to generate direct feeds to the TSPA-LA. The purpose was specified by, and the evaluation was performed and is documented in accordance with, ''Technical Work Plan For: Near-Field Environment and Transport In-Drift Geochemistry Analyses'' (BSC 2004 [DIRS 172402], Section 2.1). This report addresses all of the FEPs assigned by the technical work plan (TWP), including the development of exclusion arguments for FEPs that are not carried forward to the TSPA-LA. Except for an editorial correction noted in Section 6.2, there were no other deviations from the TWP. This report documents the completion of all assigned tasks, as follows (BSC 2004 DIRS 172402, Section 1.2.1): (1) Perform analyses to evaluate the potential for microbial activity in the waste emplacement drift under the constraints of anticipated physical and chemical conditions. (2) Evaluate uncertainties associated with these analyses. (3) Determine whether the potential for microbes warrants a feed to TSPA-LA to account for predicted effects on repository performance. (4) Provide information to address the ''Yucca Mountain Review Plan, Final Report'' (NUREG-1804) (NRC 2003 [DIRS 163274]) and Key Technical Issues and agreements, as appropriate. (5) Develop information for inclusion or exclusion of FEPs.

  20. RELAP5-3D Developmental Assessment. Comparison of Version 4.3.4i on Linux and Windows

    SciTech Connect

    Bayless, Paul David

    2015-10-01

    Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code, version 4.3i, compiled on Linux and Windows platforms. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions differ between the Linux and Windows versions.

  1. RELAP5-3D Developmental Assessment: Comparison of Version 4.2.1i on Linux and Windows

    SciTech Connect

    Paul D. Bayless

    2014-06-01

    Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code, version 4.2i, compiled on Linux and Windows platforms. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions differ between the Linux and Windows versions.

  2. Program Evaluation: Planning and Conducting Evaluations

    Energy.gov [DOE]

    This area of the website takes you through step-by-step processes for planning and conducting the In-progress Peer Reviews and Impact Evaluations described on this website. In general, for each...

  3. The Partnership Evaluation Framework

    Energy.gov [DOE]

    U.S. Department of Energy Better Buildings Neighborhood Program: The Partnership Evaluation Framework: How to evaluate a potential partner’s business model and identify areas for collaboration.

  4. Technical and systems evaluations

    SciTech Connect

    Skolnik, E.G.; DiPietro, J.P.

    1998-08-01

    During FY 1998 Energetics performed a variety of technology-based evaluations for the Hydrogen Program. Three evaluations are summarized below: hydrogen bromine-based electricity storage, carbon-based hydrogen storage, and hydrogen-fueled buses.

  5. Program Evaluation: Monitor Implementation

    Energy.gov [DOE]

    Once you have chosen the evaluation contractor, the next step is to work with the contractor to get the evaluation plan finalized and to provide the lists and other assistance the contractor needs....

  6. Program Evaluation: Lessons Learned

    Energy.gov [DOE]

    A number of lessons have been learned from implementing peer reviews and critiques of past (pre-2006) outcome/impact evaluation studies that will help improve evaluation practice in EERE. Awareness...

  7. Advanced Vehicle Testing & Evaluation

    Energy.gov [DOE]

    2013 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting

  8. Advanced Vehicle Testing & Evaluation

    Energy.gov [DOE]

    2012 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting

  9. Advanced Vehicle Testing & Evaluation

    Energy.gov [DOE]

    2011 DOE Hydrogen and Fuel Cells Program, and Vehicle Technologies Program Annual Merit Review and Peer Evaluation

  10. Safeguards Analytical Laboratory Evaluation (SALE) 1979 annual report

    SciTech Connect

    Not Available

    1980-07-01

    The data in this report indicate that reliability of measurements is probably more closely associated with the methods of measurement employed by the laboratories than with any other factor. However, since other laboratories use, with success, the same methods that show some diversity in laboratory means with success, it must be concluded that factors relating to measurement control within a given laboratory may be responsible for inaccurate or imprecise results. The relatively small quantity of data reported for the analysis of plutonium-bearing materials does not permit an in-depth evaluation of measurement performance. The data demonstrate that random and systematic errors associated with uranium measurements are within acceptable limits and that measurement performance in the analysis of low enriched uranium can be considered as good to excellent. The measurement performance related to plutonium-bearing materials appears to be acceptable based on the limited data available. However, developmental activities designed to improve plutonium measurement technology should be expedited.

  11. Hanford performance evaluation program for Hanford site analytical services

    SciTech Connect

    Markel, L.P.

    1995-09-01

    The U.S. Department of Energy (DOE) Order 5700.6C, Quality Assurance, and Title 10 of the Code of Federal Regulations, Part 830.120, Quality Assurance Requirements, states that it is the responsibility of DOE contractors to ensure that ``quality is achieved and maintained by those who have been assigned the responsibility for performing the work.`` Hanford Analytical Services Quality Assurance Plan (HASQAP) is designed to meet the needs of the Richland Operations Office (RL) for maintaining a consistent level of quality for the analytical chemistry services provided by contractor and commmercial analytical laboratory operations. Therefore, services supporting Hanford environmental monitoring, environmental restoration, and waste management analytical services shall meet appropriate quality standards. This performance evaluation program will monitor the quality standards of all analytical laboratories supporting the Hanforad Site including on-site and off-site laboratories. The monitoring and evaluation of laboratory performance can be completed by the use of several tools. This program will discuss the tools that will be utilized for laboratory performance evaluations. Revision 0 will primarily focus on presently available programs using readily available performance evaluation materials provided by DOE, EPA or commercial sources. Discussion of project specific PE materials and evaluations will be described in section 9.0 and Appendix A.

  12. American Evaluation Association Guiding Principles for Evaluators, 2004 |

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Department of Energy American Evaluation Association Guiding Principles for Evaluators, 2004 American Evaluation Association Guiding Principles for Evaluators, 2004 Five principles developed by American Evaluation Associ intended to guide professional practice of evaluators & to inform evaluation clients and the general public about principles they can expect to be upheld by professional evaluators. Guiding Principles for Evaluators (204.88 KB) More Documents & Publications ORSSAB

  13. Test and evaluation capabilities at NAVELEXCEN Charleston

    SciTech Connect

    Stalvey, T.W.; Anderson, G.B.; Hinson, T.L.

    1993-12-31

    The Environmental Systems and Instrumentation Engineering Department is located within the Special Programs Directorate of the Naval Electronic Systems Engineering Center (NAVELEXCEN Charleston). This Center is an echelon 4 Command under the Naval Command Control and Ocean Surveillance Center, San Diego (NCCOSC). NCCOSC is an echelon 3 Command under the Space and Warfare Systems Command (SPAWAR) which is located in Washington DC. Radiation Detection, Indication and Computation (RDIAC) equipment life-cycle management for the entire Navy falls under the auspices of the Naval Sea Systems Command (SEA 04R). The RADIAC Program provides centralized management for the execution of research, development, test, evaluation, maintenance, procurement, allowance, and equipment support for all Navy RADIAC instrumentation and assigned special monitoring equipments. RADIAC equipment is used throughout the Navy to support various functions associated with radioactivity, potential contamination, and personnel exposure to sources of ionizing radiation. Common sources in today`s Navy include nuclear reactors, nuclear weapons, industrial radiography, and nuclear medicine. Types of radiation includes gamma, x-ray, alpha, and beta.

  14. Exposure Evaluation Process

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Exposure Evaluation Process for Tank Farm Workers L.B. Sandy Rock, MD, MPH Risk Communication HPMC Occupational Medical Services An increase in the number of tank farm vapor exposures has led to many questions and concerns among workers and management. * During regular clinic hours, HPMC OMS is responsible for the medical evaluation of workers reporting exposure to vapors. * At other times, workers are taken to Kadlec Hospital which has an arrangement with DOE/HPMC OMS to evaluate, treat, refer

  15. Service Center Evaluation Guide

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Evaluation Guide, Selected Bibliography on Electric Motor Repair, Model Repair Specifications for Low Voltage Motors, and Motor Repair Tech Brief- were produced by the U.S. ...

  16. Precursor and Fiber Evaluation

    Energy.gov [DOE]

    2009 DOE Hydrogen Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting, May 18-22, 2009 -- Washington D.C.

  17. Evaluation Project 4492

    National Nuclear Security Administration (NNSA)

    the Kansas City Plant (KCP) in Kansas City, Missouri to evaluate parts that have undergone testing. Sandia Site Office Postmortem Code Blue--Kansas City Plant (KCP) Kansas ...

  18. Fast Neutron Detection Evaluation

    SciTech Connect

    McKigney, Edward A.; Stange, Sy

    2014-03-17

    These slides present a summary of previous work, conclusions, and anticipated schedule for the conclusion of our fast neutron detection evaluation.

  19. ORISE: Research and Evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    are built on solid research and evaluation. This information helps agencies refine the design, implementation and overall quality of a communication intervention. To support the...

  20. MSA Evaluation Archive

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Education Teachers (K-12) Archive MSA Evaluation Archive The Laboratory's Math and Science Academy provides quality STEM education professional development for teachers in...

  1. test and evaluation

    National Nuclear Security Administration (NNSA)

    5%2A en Office of Test and Evaluation http:nnsa.energy.govaboutusourprogramsdefenseprogramsstockpilestewardshiptestcapabilitiesand-eval

  2. Project Evaluation Models

    Office of Environmental Management (EM)

    ... to evaluate its performance and lowest cost of energy * Uses hourly resource data for wind and solar Renewable Energy Options * Models existing generation (Grid, backup ...

  3. Aroclor 1254, a developmental neurotoxicant, alters energy metabolism- and intracellular signaling-associated protein networks in rat cerebellum and hippocampus

    SciTech Connect

    Kodavanti, Prasada Rao S.; Osorio, Cristina; Program on Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, North Carolina ; Royland, Joyce E.; Ramabhadran, Ram; Alzate, Oscar; Systems Proteomics Center, University of North Carolina at Chapel Hill, North Carolina; Program on Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, North Carolina

    2011-11-15

    The vast literature on the mode of action of polychlorinated biphenyls (PCBs) indicates that PCBs are a unique model for understanding the mechanisms of toxicity of environmental mixtures of persistent chemicals. PCBs have been shown to adversely affect psychomotor function and learning and memory in humans. Although the molecular mechanisms for PCB effects are unclear, several studies indicate that the disruption of Ca{sup 2+}-mediated signal transduction plays significant roles in PCB-induced developmental neurotoxicity. Culminating events in signal transduction pathways include the regulation of gene and protein expression, which affects the growth and function of the nervous system. Our previous studies showed changes in gene expression related to signal transduction and neuronal growth. In this study, protein expression following developmental exposure to PCB is examined. Pregnant rats (Long Evans) were dosed with 0.0 or 6.0 mg/kg/day of Aroclor-1254 from gestation day 6 through postnatal day (PND) 21, and the cerebellum and hippocampus from PND14 animals were analyzed to determine Aroclor 1254-induced differential protein expression. Two proteins were found to be differentially expressed in the cerebellum following PCB exposure while 18 proteins were differentially expressed in the hippocampus. These proteins are related to energy metabolism in mitochondria (ATP synthase, sub unit {beta} (ATP5B), creatine kinase, and malate dehydrogenase), calcium signaling (voltage-dependent anion-selective channel protein 1 (VDAC1) and ryanodine receptor type II (RyR2)), and growth of the nervous system (dihydropyrimidinase-related protein 4 (DPYSL4), valosin-containing protein (VCP)). Results suggest that Aroclor 1254-like persistent chemicals may alter energy metabolism and intracellular signaling, which might result in developmental neurotoxicity. -- Highlights: Black-Right-Pointing-Pointer We performed brain proteomic analysis of rats exposed to the neurotoxicant

  4. Program Evaluation: Use the Results

    Energy.gov [DOE]

    Communicating and disseminating the evaluation findings is a critical step in building support for utilizing those findings. Managers of the evaluation and evaluators should plan the reporting...

  5. MSA Evaluation Archive

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Education » Teachers (K-12) » Archive MSA Evaluation Archive The Laboratory's Math and Science Academy provides quality STEM education professional development for teachers in participating schools and districts. Contact Math and Science Academy Community Partnerships Office (505) 665-4400 MSA Program Evaluations FY13-14 (pdf) FY12-13 (pdf) FY11-12

  6. Developmental test report, assessment of XT-70E percussion drill rig operation in tank farms

    SciTech Connect

    Dougherty, L.F., Westinghouse Hanford

    1996-09-10

    The following report documents the testing of the XT-70E percussion drill rig for use in the 241-SX Tank Farm. The test is necessary to support evaluation of the safety and authorization level of the proposed activity of installing up to three new drywells in the 241- SX Tank Farm. The proposed activity plans to install drywells by percussion drilling 7 inch O.D./6 inch I.D. pipe in close proximity of underground storage tanks and associated equipment. The load transmitted from the drill rig`s percussion hammer through the ground to the tank structure and equipment is not known and therefore testing is required to ensure the activity is safe and authorized.

  7. BUILDING 341 Seismic Evaluation

    SciTech Connect

    Halle, J.

    2015-06-15

    The Seismic Evaluation of Building 341 located at Lawrence Livermore National Laboratory in Livermore, California has been completed. The subject building consists of a main building, Increment 1, and two smaller additions; Increments 2 and 3.

  8. Internal Controls Evaluations

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    4, 2016 U.S. DEPARTMENT OF ENERGY Internal Control Evaluations Fiscal Year 2016 Guidance Page | 2 Table of Contents I. Introduction .............................................................................................................................................. 4 A. Background ......................................................................................................................................... 4 B. New for FY

  9. Market Effects Evaluation Report

    Energy.gov [DOE]

    A report evaluating the U.S. Department of Energy Solid State Lighting Program for FY 2006 – FY 2012 to determine its effectiveness and progress toward achieving program objectives and to assess...

  10. Evaluated Nuclear Data

    SciTech Connect

    Oblozinsky, P.; Oblozinsky,P.; Herman,M.; Mughabghab,S.F.

    2010-10-01

    This chapter describes the current status of evaluated nuclear data for nuclear technology applications. We start with evaluation procedures for neutron-induced reactions focusing on incident energies from the thermal energy up to 20 MeV, though higher energies are also mentioned. This is followed by examining the status of evaluated neutron data for actinides that play dominant role in most of the applications, followed by coolants/moderators, structural materials and fission products. We then discuss neutron covariance data that characterize uncertainties and correlations. We explain how modern nuclear evaluated data libraries are validated against an extensive set of integral benchmark experiments. Afterwards, we briefly examine other data of importance for nuclear technology, including fission yields, thermal neutron scattering and decay data. A description of three major evaluated nuclear data libraries is provided, including the latest version of the US library ENDF/B-VII.0, European JEFF-3.1 and Japanese JENDL-3.3. A brief introduction is made to current web retrieval systems that allow easy access to a vast amount of up-to-date evaluated nuclear data for nuclear technology applications.

  11. MODULAR CONSTRUCTION SYSTEM EVALUATION

    SciTech Connect

    S. Gillespie

    2002-08-08

    The purpose of this study is to respond to U.S. Department of Energy (DOE) Technical Direction Letter (TDL) 02-003 (Waisley 2001), which directs Bechtel SAIC Company, LLC (BSC) to complete a design study to recommend repository design options to support receipt and/or emplacement of any or all of the following: commercial spent nuclear fuel (CSNF), high-level radioactive waste (HLW), DOE-managed spent nuclear fuel (DSNF) (including naval spent nuclear fuel [SNF]), and immobilized plutonium (if available), as soon as practicable, but no later than 2010. From the possible design options, a recommended approach will be determined for further evaluation to support the preliminary design of the repository. This study integrates the results of the repository Design Evolution Study (Rowe 2002) with supporting studies concerning national transportation options (BSC 2002b) and Nevada transportation options (Gehner 2002). The repository Design Evolution Study documents the processes used to reevaluate the design, construction, operation, and cost of the repository in response to TDL 02-003 (Waisley 2001), and to determine possible repository conceptual design options. The transportation studies evaluate the national and Nevada transportation options that support the repository conceptual design options. An evaluation methodology was established, based on Program-level requirements developed for the study in reference BSC 2001a, to allow the repository and system design options to be evaluated on a consistent basis. The transportation options and the design components were integrated into system design implementation options, which were evaluated using receipt and emplacement scenarios. The scenarios tested the ability of the design concept to adapt to changes in funding, waste receipt rate, and Nevada rail transportation availability. The results of the evaluation (in terms of system throughput, cost, and schedule) were then compared to the Program-level requirements, and

  12. Design and evaluation of small water turbines. Final report

    SciTech Connect

    Marquis, J.A.

    1983-02-17

    An evaluation was made of the design and hydromechanical performance characteristics for three basic turbine types: axial flow (Jonval), inward radial flow (Francis) and crossflow (Banki). A single commercially available turbine representative of each type and within the appropriate power range (<5hp) was obtained for evaluation. Specific turbine selections were based on price, availability and suitability for operation at heads of 50 feet or less and flows under 2 cubic feet per second. In general, the peak operating efficiencies of each unit tended to be lower than anticipated, falling in the range of 40 to 50%. With sufficient flow, however, significant useful power outputs up to 3 hp were obtained. While the radial flow turbine (a centrifugal pump operated as a turbine) had the lowest initial unit cost, the axial and cross flow designs exhibited more stable operation, particularly under transient loadings. The crossflow turbine had the added advantage that it was essentially self-cleaning. With further developmental effort and appropriate design modifications it should be possible to bring each of these microhydro designs to their full performance potential.

  13. Program Evaluation: EERE Planned and Completed Evaluations | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Energy Evaluation » Information Resources » Program Evaluation: EERE Planned and Completed Evaluations Program Evaluation: EERE Planned and Completed Evaluations This section provides a list of past and planned evaluation reports for the U.S. Department of Energy's (DOE) Office of Energy Efficiency and Renewable Energy (EERE). Many of the listed reports are available as downloads. The table below tells you which offices have reports accessible as downloads. A checked box in the table -

  14. Evaluation of accountability measurements

    SciTech Connect

    Cacic, C.G.

    1988-01-01

    The New Brunswick Laboratory (NBL) is programmatically responsible to the U.S. Department of Energy (DOE) Office of Safeguards and Security (OSS) for providing independent review and evaluation of accountability measurement technology in DOE nuclear facilities. This function is addressed in part through the NBL Safegaurds Measurement Evaluation (SME) Program. The SME Program utilizes both on-site review of measurement methods along with material-specific measurement evaluation studies to provide information concerning the adequacy of subject accountability measurements. This paper reviews SME Program activities for the 1986-87 time period, with emphasis on noted improvements in measurement capabilities. Continued evolution of the SME Program to respond to changing safeguards concerns is discussed.

  15. Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Administration; Appendix Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for the U.S. Department of Energy and the Federal Transit Administration; Appendix ...

  16. Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Administration Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for the U.S. Department of Energy and the Federal Transit Administration This document ...

  17. Soil washing technology evaluation

    SciTech Connect

    Suer, A.

    1995-04-01

    Environmental Restoration Engineering (ERE) continues to review innovative, efficient, and cost effective technologies for SRS soil and/or groundwater remediation. As part of this effort, this technical evaluation provides review and the latest information on the technology for SRS soil remediation. Additional technology evaluation reports will be issued periodically to update these reports. The purpose of this report is to review the soil washing technology and its potential application to SRS soil remediation. To assess whether the Soil Washing technology is a viable option for SRS soil remediation, it is necessary to review the technology/process, technology advantages/limitations, performance, applications, and cost analysis.

  18. Developmentally regulated expression by Trypanosoma cruzi of molecules that accelerate the decay of complement C3 convertases

    SciTech Connect

    Rimoldi, M.T.; Sher, A.; Heiny, A.; Lituchy, A.; Hammer, C.H.; Joiner, K.

    1988-01-01

    The authors recently showed that culture-derived metacyclic trypomastigotes (CMT), but not epimastigotes (Epi), of the Miranda 99 strain of Trypanosoma cruzi evade lysis by the human alternative complement pathway because of inefficient binding of factor B to complement component C3b on the parasite surface. These results suggested that CMT and tissue-culture-derived trypomastigotes (TCT), which also activate the alternative pathway poorly, might produce a molecule capable of interfering with factor B binding to C3b. They now demonstrate that CMT and TCT lysates, as well as molecules spontaneously shed from CMT and TCT but not Epi, accelerate decay of /sup 125/I-labeled factor Bb from the alternative-pathway C3 convertase (C3bBb) assembled on zymosan or Epi and also accelerate decay of the classical-pathway C3 convertase (C4b2a) on sheep erythrocytes. Parasites metabolically labeled with (/sup 35/S)methionine spontaneously shed a limited number of radioactive components, ranging in molecular mass from 86 to 155 kDa for trypomastigotes and 25 to 80 kDa for Epi. Decay-accelerating activity within supernatants is inactivated by papain and is coeluted with /sup 35/S-containing polypeptides on FPLC anion-exchange chromatography, suggesting that the active constituents are protein molecules. Molecules with decay-accelerating activity may explain the developmentally regulated resistance to complement-mediated lysis in infective and vertebrate stages for T. cruzi life cycle.

  19. Survey of the high resolution infrared spectrum of methane ({sup 12}CH{sub 4} and {sup 13}CH{sub 4}): Partial vibrational assignment extended towards 12000 cm{sup ?1}

    SciTech Connect

    Ulenikov, O. N.; Bekhtereva, E. S.; Albert, S.; Bauerecker, S.; Niederer, H. M.; Quack, M.

    2014-12-21

    We have recorded the complete infrared spectrum of methane {sup 12}CH{sub 4} and its second most abundant isotopomer {sup 13}CH{sub 4} extending from the fundamental range starting at 1000 cm{sup ?1} up to the overtone region near 12000 cm{sup ?1} in the near infrared at the limit towards the visible range, at temperatures of about 80 K and also at 298 K with Doppler limited resolution in the gas phase by means of interferometric Fourier transform spectroscopy using the Bruker IFS 125 HR prototype (ZP 2001) of the ETH Zrich laboratory. This provides the so far most complete data set on methane spectra in this range at high resolution. In the present work we report in particular those results, where the partial rovibrational analysis allows for the direct assignment of pure (J = 0) vibrational levels including high excitation. These results substantially extend the accurate knowledge of vibrational band centers to higher energies and provide a benchmark for both the comparison with theoretical results on the one hand and atmospheric spectroscopy on the other hand. We also present a simple effective Hamiltonian analysis, which is discussed in terms of vibrational level assignments and {sup 13}C isotope effects.

  20. Millimeter-wave optical double resonance schemes for rapid assignment of perturbed spectra, with applications to the C{sup ~} {sup 1}B{sub 2} state of SO{sub 2}

    SciTech Connect

    Park, G. Barratt E-mail: barratt.park@gmail.com; Womack, Caroline C.; Jiang, Jun; Field, Robert W.; Whitehill, Andrew R.; Ono, Shuhei

    2015-04-14

    Millimeter-wave detected, millimeter-wave optical double resonance (mmODR) spectroscopy is a powerful tool for the analysis of dense, complicated regions in the optical spectra of small molecules. The availability of cavity-free microwave and millimeter wave spectrometers with frequency-agile generation and detection of radiation (required for chirped-pulse Fourier-transform spectroscopy) opens up new schemes for double resonance experiments. We demonstrate a multiplexed population labeling scheme for rapid acquisition of double resonance spectra, probing multiple rotational transitions simultaneously. We also demonstrate a millimeter-wave implementation of the coherence-converted population transfer scheme for background-free mmODR, which provides a ∼10-fold sensitivity improvement over the population labeling scheme. We analyze perturbations in the C{sup ~} state of SO{sub 2}, and we rotationally assign a b{sub 2} vibrational level at 45 328 cm{sup −1} that borrows intensity via a c-axis Coriolis interaction. We also demonstrate the effectiveness of our multiplexed mmODR scheme for rapid acquisition and assignment of three predissociated vibrational levels of the C{sup ~} state of SO{sub 2} between 46 800 and 47 650 cm{sup −1}.

  1. A=3, 2010 evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    3 (2010PU04) (Revised Manuscript from 2010) An evaluation of A = 3 was published in Nuclear Physics A848 (2010) p. 1. The version here differs from the published version in that we have corrected a few errors discovered after the article went to press. PDF HTML A = 3 3n, 3H, 3He, 3Li Adobe Reader Download Last modified: 01

  2. Photovoltaic Systems Evaluation Laboratory (PSEL)

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Energy Systems LaboratoryBrayton Lab Photovoltaic Systems Evaluation Laboratory PV ... Twitter Google + Vimeo Newsletter Signup SlideShare Photovoltaic Systems Evaluation ...

  3. Program Evaluation: Requirements and Expectations

    Energy.gov [DOE]

    Throughout this website, emphasis is placed on evaluation as a good management practice that helps managers make informed decisions. Ideally, offices are motivated to undertake evaluation-related...

  4. Performance Evaluation and MEasurement Plan

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    PERFORMANCE EVALUATION AND MEASUREMENT PLAN Fiscal Year 2017 Occupational Medical ... Performance Evaluation and Measurement Plan (PEMP) Table of Contents 1.0 INTRODUCTION ...

  5. Program Evaluation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Program Evaluation The Office of Energy Efficiency and Renewable Energy (EERE) takes an active role in measuring and evaluating its projects and programs. One focus of these ...

  6. Programs Planning to Do Evaluations

    Energy.gov [DOE]

    Better Buildings Neighborhood Program Data and Evaluation Peer Exchange Call: Programs Planning to Do Evaluations, Call Slides and Discussion Summary, August 2, 2012.

  7. THE AIMS AND ACTIVITIES OF THE INTERNATIONAL NETWORK OF NUCLEAR STRUCTURE AND DECAY DATA EVALUATORS.

    SciTech Connect

    NICHOLS,A.L.; TULI, J.K.

    2007-04-22

    International Network of Nuclear Structure and Decay Data (NSDD) Evaluators consists of a number of evaluation groups and data service centers in several countries that appreciate the merits of working together to maintain and ensure the quality and comprehensive content of the ENSDF database (Evaluated Nuclear Structure Data File). Biennial meetings of the network are held under the auspices of the International Atomic Energy Agency (IAEA) to assign evaluation responsibilities, monitor progress, discuss improvements and emerging difficulties, and agree on actions to be undertaken by individual members. The evaluated data and bibliographic details are made available to users via various media, such as the journals ''Nuclear Physics A'' and ''Nuclear Data Sheets'', the World Wide Web, on CD-ROM, wall charts of the nuclides and ''Nuclear Wallet Cards''. While the ENSDF master database is maintained by the US National Nuclear Data Center at the Brookhaven National Laboratory, these data are also available from other nuclear data centers including the IAEA Nuclear Data Section. The Abdus Salam International Centre for Theoretical Physics (ICTP), Trieste, Italy, in cooperation with the IAEA, organizes workshops on NSDD at regular intervals. The primary aims of these particular workshops are to provide hands-on training in the data evaluation processes, and to encourage new evaluators to participate in NSDD activities. The technical contents of these NSDD workshops are described, along with the rationale for the inclusion of various topics.

  8. Candidate Assembly Statistical Evaluation

    Energy Science and Technology Software Center

    1998-07-15

    The Savannah River Site (SRS) receives aluminum clad spent Material Test Reactor (MTR) fuel from all over the world for storage and eventual reprocessing. There are hundreds of different kinds of MTR fuels and these fuels will continue to be received at SRS for approximately ten more years. SRS''s current criticality evaluation methodology requires the modeling of all MTR fuels utilizing Monte Carlo codes, which is extremely time consuming and resource intensive. Now that amore » significant number of MTR calculations have been conducted it is feasible to consider building statistical models that will provide reasonable estimations of MTR behavior. These statistical models can be incorporated into a standardized model homogenization spreadsheet package to provide analysts with a means of performing routine MTR fuel analyses with a minimal commitment of time and resources. This became the purpose for development of the Candidate Assembly Statistical Evaluation (CASE) program at SRS.« less

  9. BUILDING AMERICA PROGRAM EVALUATION

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    BUILDING AMERICA PROGRAM EVALUATION _______________________________ Volume II: Appendices Prepared by: Energy Technology Innovation Project (ETIP) Kennedy School of Government, Harvard University Vicki Norberg-Bohm, Principal Investigator Chad White, Lead Author September 2004 Appendix A. Building America Program Intent and Scope 1 Appendix A-1. Program Overview A-1.1. Program History Building America has its origins in a 1993 pilot project between DOE and a housing products unit at General

  10. A=11, 2012 evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    11 (2012KE01) (Revised Manuscript from 2012) An evaluation of A = 11 was published in Nuclear Physics A880 (2012) p. 88. The version here differs from the published version in that we have corrected a few errors discovered after the article went to press. PDF HTML A = 11 11He,11Li, 11Be, 11B, , 11C, , 11N, , 11O, , 11F, ,11Ne Adobe Reader Download Last modified: 23 April 2012

  11. Electromelt furnace evaluation

    SciTech Connect

    Reimann, G.A.; Welch, J.M.

    1981-09-01

    An electromelt furnace was designed, built, and operated at the Idaho National Engineering Laboratory to demonstrate the suitability of this equipment for large-scale processing of radioactive wastes in iron-enriched basalt. Several typical waste compositions were melted and cast. The furnace was disassembled and the components evaluated. Calcines and fluorides attacked the furnace lining, unoxidized metals accumulated under the slag, and electrode attrition was high.

  12. Provenance Store Evaluation

    SciTech Connect

    Paulson, Patrick R.; Gibson, Tara D.; Schuchardt, Karen L.; Stephan, Eric G.

    2008-03-01

    Requirements for the provenance store and access API are developed. Existing RDF stores and APIs are evaluated against the requirements and performance benchmarks. The team’s conclusion is to use MySQL as a database backend, with a possible move to Oracle in the near-term future. Both Jena and Sesame’s APIs will be supported, but new code will use the Jena API

  13. Evaluating Soviet ESP technology

    SciTech Connect

    Pike, W.J. )

    1991-05-01

    This paper evaluates Soviet ESP technology. The Soviet Union currently produces approximately half of its oil with electric submersible pumps (ESPs). Because of increasing water cuts in most mature fields, due in no small part to poor reservoir management, ESP use will probably continue to rise within the USSR. To meet this demand, the Soviets have developed the largest ESP manufacturing capacity in the world. Soviet ESPs offer some interesting features and are reported to have impressive running lives.

  14. Evaluations | Argonne National Laboratory

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Evaluations It is essential that postdoctoral appointees and supervisors get together within two months of the starting date and fill out the Postdoctoral Initial Discussion form (ANL-698). This discussion sets initial goals and clarifies expectations on both sides for a success and productive relationship. Once completed, it has to be reviewed and signed by the Division Director. A copy should be sent to Kristene (Tina) Henne, Postdoctoral Programs Coordinator, by email to khenne@anl.gov. The

  15. Comparison of the mouse Embryonic Stem cell Test, the rat Whole Embryo Culture and the Zebrafish Embryotoxicity Test as alternative methods for developmental toxicity testing of six 1,2,4-triazoles

    SciTech Connect

    Jong, Esther de; Barenys, Marta; Hermsen, Sanne A.B.; Verhoef, Aart; Ossendorp, Bernadette C.; Bessems, Jos G.M.; Piersma, Aldert H.

    2011-06-01

    The relatively high experimental animal use in developmental toxicity testing has stimulated the search for alternatives that are less animal intensive. Three widely studied alternative assays are the mouse Embryonic Stem cell Test (EST), the Zebrafish Embryotoxicity Test (ZET) and the rat postimplantation Whole Embryo Culture (WEC). The goal of this study was to determine their efficacy in assessing the relative developmental toxicity of six 1,2,4-triazole compounds, flusilazole, hexaconazole, cyproconazole, triadimefon, myclobutanil and triticonazole. For this purpose, we analyzed effects and relative potencies of the compounds in and among the alternative assays and compared the findings to their known in vivo developmental toxicity. Triazoles are antifungal agents used in agriculture and medicine, some of which are known to induce craniofacial and limb abnormalities in rodents. The WEC showed a general pattern of teratogenic effects, typical of exposure to triazoles, mainly consisting of reduction and fusion of the first and second branchial arches, which are in accordance with the craniofacial malformations reported after in vivo exposure. In the EST all triazole compounds inhibited cardiomyocyte differentiation concentration-dependently. Overall, the ZET gave the best correlation with the relative in vivo developmental toxicities of the tested compounds, closely followed by the EST. The relative potencies observed in the WEC showed the lowest correlation with the in vivo developmental toxicity data. These differences in the efficacy between the test systems might be due to differences in compound kinetics, in developmental stages represented and in the relative complexity of the alternative assays.

  16. Impaired Chloroplast Biogenesis in Immutans, an Arabidopsis Variegation Mutant, Modifies Developmental Programming, Cell Wall Composition and Resistance to Pseudomonas syringae

    DOE PAGES [OSTI]

    Pogorelko, Gennady V.; Kambakam, Sekhar; Nolan, Trevor; Foudree, Andrew; Zabotina, Olga A.; Rodermel, Steven R.

    2016-04-06

    The immutans (im) variegation mutation of Arabidopsis has green- and white- sectored leaves due to action of a nuclear recessive gene. IM codes for PTOX, a plastoquinol oxidase in plastid membranes. Previous studies have revealed that the green and white sectors develop into sources (green tissues) and sinks (white tissues) early in leaf development. In this report we focus on white sectors, and show that their transformation into effective sinks involves a sharp reduction in plastid number and size. Despite these reductions, cells in the white sectors have near-normal amounts of plastid RNA and protein, and surprisingly, a marked amplificationmore » of chloroplast DNA. The maintenance of protein synthesis capacity in the white sectors might poise plastids for their development into other plastid types. The green and white im sectors have different cell wall compositions: whereas cell walls in the green sectors resemble those in wild type, cell walls in the white sectors have reduced lignin and cellulose microfibrils, as well as alterations in galactomannans and the decoration of xyloglucan. These changes promote susceptibility to the pathogen Pseudomonas syringae. Enhanced susceptibility can also be explained by repressed expression of some, but not all, defense genes. We suggest that differences in morphology, physiology and biochemistry between the green and white sectors is caused by a reprogramming of leaf development that is coordinated, in part, by mechanisms of retrograde (plastid-tonucleus) signaling, perhaps mediated by ROS. Lastly, we conclude that variegation mutants offer a novel system to study leaf developmental programming, cell wall metabolism and hostpathogen interactions.« less

  17. Quantitative GFP fluorescence as an indicator of arsenite developmental toxicity in mosaic heat shock protein 70 transgenic zebrafish

    SciTech Connect

    Seok, Seung-Hyeok; Baek, Min-Won; Lee, Hui-Young; Kim, Dong-Jae; Na, Yi-Rang; Noh, Kyoung-Jin; Park, Sung-Hoon; Lee, Hyun-Kyoung; Lee, Byoung-Hee; Ryu, Doug-Young; Park, Jae-Hak

    2007-12-01

    In transgenic zebrafish (Danio rerio), green fluorescent protein (GFP) is a promising marker for environmental pollutants. In using GFP, one of the obstacles which we faced was how to compare toxicity among different toxicants or among a specific toxicant in different model species with the intensity of GFP expression. Using a fluorescence detection method, we first validated our method for estimating the amount of GFP fluorescence present in transgenic fish, which we used as an indicator of developmental toxicity caused by the well-known toxicant, arsenite. To this end, we developed mosaic transgenic zebrafish with the human heat shock response element (HSE) fused to the enhanced GFP (EGFP) reporter gene to indicate exposure to arsenite. We confirmed that EGFP expression sites correlate with gross morphological disruption caused by arsenite exposure. Arsenite (300.0 {mu}M) caused stronger EGFP fluorescence intensity and quantity than 50.0 {mu}M and 10.0 {mu}M arsenite in our transgenic zebrafish. Furthermore, arsenite-induced apoptosis was demonstrated by TUNEL assay. Apoptosis was inhibited by the antioxidant, N-acetyl-cystein (NAC) in this transgenic zebrafish. The distribution of TUNEL-positive cells in embryonic tissues was correlated with the sites of arsenite toxicity and EGFP expression. The EGFP values quantified using the standard curve equation from the known GFP quantity were consistent with the arsenite-induced EGFP expression pattern and arsenite concentration, indicating that this technique can be a reliable and applicable measurement. In conclusion, we propose that fluorescence-based EGFP quantification in transgenic fish containing the hsp70 promoter-EGFP reporter-gene construct is a useful indicator of development toxicity caused by arsenite.

  18. TUNL Nuclear Data Evaluation Group

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    TUNL Nuclear Data Evaluation Group As a part of the United States Nuclear Data Network and the international Nuclear Structure and Decay Data Evaluators' Network, the Nuclear Data group at the Triangle Universities Nuclear Laboratory (TUNL) is responsible for evaluations of nuclei in the mass range A = 3 - 20. The current status of these evaluations is summarized below: Nuclear Mass: Latest Publication: Evaluated By: A = 3 Nucl. Phys. A848 (2010) 1 TUNL A = 4 Nucl. Phys. A541 (1992) 1 TUNL (#) A

  19. A=20, 1998 evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    20 (1998TI06) (Revised Manuscript from 1998) An evaluation of A = 20 was published in Nuclear Physics A636 (1998) p. 247. The version here lacks the introduction and overview tables that appeared in the full version, and is arranged in a different manner. The figures are present in this pdf document, and are available elsewhere on this server (see below). PDF HTML Figures A = 20 20n, 20He, 20Li, 20Be, 20B, 20C, 20N, 20O, 20F, 20Ne, 20Na, 20Mg, 20Al A = 20

  20. A=4, 1992 evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    4 (1992TI02) (Revised Manuscript from 1992) An evaluation of A = 4 was published in Nuclear Physics A541 (1992) p. 1. The version here differs from the published version in that we have corrected a few errors discovered after the article went to press. Introduction and overview tables have been omitted from this manuscript. Reference key numbers have been changed to the NNDC/TUNL format. The figures are now present in the pdf document, and are also available elsewhere on this server (see below).

  1. Detached rock evaluation device

    DOEpatents

    Hanson, David R.

    1986-01-01

    A rock detachment evaluation device (10) having an energy transducer unit 1) for sensing vibrations imparted to a subject rock (172) for converting the sensed vibrations into electrical signals, a low band pass filter unit (12) for receiving the electrical signal and transmitting only a low frequency segment thereof, a high band pass filter unit (13) for receiving the electrical signals and for transmitting only a high frequency segment thereof, a comparison unit (14) for receiving the low frequency and high frequency signals and for determining the difference in power between the signals, and a display unit (16) for displaying indicia of the difference, which provides a quantitative measure of rock detachment.

  2. TEPP - Exercise Evaluation Forms | Department of Energy

    Office of Environmental Management (EM)

    TEPP - Exercise Evaluation Forms TEPP - Exercise Evaluation Forms Hazardous Materials Exercise Evaluation Forms PDF icon Exercise Evaluation Forms More Documents & Publications...

  3. Use of genomic data in risk assessment case study: I. Evaluation of the dibutyl phthalate male reproductive development toxicity data set

    SciTech Connect

    Makris, Susan L.; Euling, Susan Y.; Gray, L. Earl; Benson, Robert; Foster, Paul M.D.

    2013-09-15

    A case study was conducted, using dibutyl phthalate (DBP), to explore an approach to using toxicogenomic data in risk assessment. The toxicity and toxicogenomic data sets relative to DBP-related male reproductive developmental outcomes were considered conjointly to derive information about mode and mechanism of action. In this manuscript, we describe the case study evaluation of the toxicological database for DBP, focusing on identifying the full spectrum of male reproductive developmental effects. The data were assessed to 1) evaluate low dose and low incidence findings and 2) identify male reproductive toxicity endpoints without well-established modes of action (MOAs). These efforts led to the characterization of data gaps and research needs for the toxicity and toxicogenomic studies in a risk assessment context. Further, the identification of endpoints with unexplained MOAs in the toxicity data set was useful in the subsequent evaluation of the mechanistic information that the toxicogenomic data set evaluation could provide. The extensive analysis of the toxicology data set within the MOA context provided a resource of information for DBP in attempts to hypothesize MOAs (for endpoints without a well-established MOA) and to phenotypically anchor toxicogenomic and other mechanistic data both to toxicity endpoints and to available toxicogenomic data. This case study serves as an example of the steps that can be taken to develop a toxicological data source for a risk assessment, both in general and especially for risk assessments that include toxicogenomic data.

  4. Treatment Deployment Evaluation Tool

    SciTech Connect

    Rynearson, Michael Ardel; Plum, Martin Michael

    1999-08-01

    The U.S. Department of Energy (DOE) is responsible for the final disposition of legacy spent nuclear fuel (SNF). As a response, DOE's National Spent Nuclear Fuel Program (NSNFP) has been given the responsibility for the disposition of DOE -owned SNF. Many treatment technologies have been identified to treat some forms of SNF so that the resulting treated product is acceptable by the disposition site. One of these promising treatment processes is the electrometallurgical treatment (EMT) currently in development; a second is an Acid Wash Decladding process. The NSNFP has been tasked with identifying possible strategies for the deployment of these treatment processes in the event that the treatment path is deemed necessary. To support the siting studies of these strategies, economic evaluations are being performed to identify the least-cost deployment path. This model (tool) was developed to consider the full scope of costs, technical feasibility, process material disposition, and schedule attributes over the life of each deployment alternative. Using standard personal computer (PC) software, the model was developed as a comprehensive technology economic assessment tool using a Life-Cycle Cost (LCC) analysis methodology. Model development was planned as a systematic, iterative process of identifying and bounding the required activities to dispose of SNF. To support the evaluation process, activities are decomposed into lower level, easier to estimate activities. Sensitivity studies can then be performed on these activities, defining cost issues and testing results against the originally stated problem.

  5. FRAPCON-2 Developmental Assessment

    SciTech Connect

    Berna, G. A.; Lanning, D. D.; Rausch, W. N.

    1981-07-01

    FRAPCON-2 calculations using all mechanical and gas release options are compared with well-characterized experimental data and with calculations of generic fuel rod response by FRAPCON-1. These comparisons indicate that FRAPCON-2 is capable of analyzing the fuel rod response for the wide range of cases for which the code was designed and compares well with experimental data.

  6. JOBAID-ASSIGNING AN ALTERNATE SUPERVISOR (SUPERVISOR)

    Energy.gov [DOE]

    The purpose of this job aid is to guide you through the step-by-step process of managing alternate supervisors within SuccessFactors Learning.

  7. Unclassified Foreign Visits and Assignments Program

    Directives, Delegations, and Other Requirements [Office of Management (MA)]

    2010-10-14

    The order defines a program for unclassified foreign national access to DOE sites, information, technologies, and equipment. Supersedes DOE O 142.3.

  8. New Issue: Moody's assigns Aa1 ...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    revenue bonds. Rating outlooks are stable. Global Credit Research - 09 Apr 2015 Approximately 8.1 billion of debt securities affected BONNEVILLE POWER ADMINISTRATION, OR Electric...

  9. New Issue: Moody's assigns Aa1 ...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    2015-C revenue bonds. Rating outlooks are stable. Global Credit Research - 23 Sep 2015 Approximately 110 million of debt securities affected BONNEVILLE POWER ADMINISTRATION, OR...

  10. Microsoft Word - CLP_Credit_Assignment_Table

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Units TRAININGEDUCATION Attendance at academic courses at an accredited college or ... (in relevant subject area or project management association) Active Membership ...

  11. Preparing for Project Implementation Assigning Accountability...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    for Each Project Save Energy Now LEADER Web Conference Project Implementation Seminar Series Save Energy Now LEADER Web Conference Agenda Seminar Series Overview ...

  12. Altered cardiovascular reactivity and osmoregulation during hyperosmotic stress in adult rats developmentally exposed to polybrominated diphenyl ethers (PBDEs)

    SciTech Connect

    Shah, Ashini; Coburn, Cary G.; Watson-Siriboe, Abena; Whitley, Rebecca; Shahidzadeh, Anoush; Gillard, Elizabeth R.; Nichol, Robert; Leon-Olea, Martha; Gaertner, Mark; Kodavanti, Prasada Rao S.

    2011-10-15

    h (358.3 {+-} 12.4 mOsm/L) relative to 45 min post hyperosmotic injection (325.1 {+-} 11.4 mOsm/L). Impaired osmoregulation in PBDE-treated animals could not be attributed to decreased levels of plasma vasopressin. Our findings suggest that developmental exposure to PBDEs may disrupt cardiovascular reactivity and osmoregulatory responses to physiological activation in late adulthood. - Highlights: > We examined whether PBDE exposure could impact osmotic and cardiovascular regulation. > Hyperosmotic treatment yielded significant changes in systolic BP in PBDE exposed rats only. > PBDEs may disrupt cardiovascular and osmoregulatory responses to physiological activation.

  13. Preliminary Process and Market Evaluation

    Energy.gov [DOE]

    Preliminary Process and Market Evaluation, from a team of evaluators, independent of the BBNP program, with whom DOE contracted to assess the performance of BBNP and identify lessons learned.

  14. SECTION M_Evaluation Factors

    National Nuclear Security Administration (NNSA)

    EVALUATION OF PROPOSALS .....................................................................................2 M-2 BASIS FOR CONTRACT AWARD ...................................................................................3 M-3 TECHNICAL AND MANAGEMENT CRITERIA ..........................................................3 M-4 COST CRITERION .............................................................................................................6 Section M, Page 2 M-1 EVALUATION OF PROPOSALS

  15. Standardized radiological dose evaluations

    SciTech Connect

    Peterson, V.L.; Stahlnecker, E.

    1996-05-01

    Following the end of the Cold War, the mission of Rocky Flats Environmental Technology Site changed from production of nuclear weapons to cleanup. Authorization baseis documents for the facilities, primarily the Final Safety Analysis Reports, are being replaced with new ones in which accident scenarios are sorted into coarse bins of consequence and frequency, similar to the approach of DOE-STD-3011-94. Because this binning does not require high precision, a standardized approach for radiological dose evaluations is taken for all the facilities at the site. This is done through a standard calculation ``template`` for use by all safety analysts preparing the new documents. This report describes this template and its use.

  16. Desalination technology evaluation

    SciTech Connect

    Del Bene, J.V.; Loh, G.T.; Schleicher, R.W.; Sgammato, T.A.; Sinha, A.K. )

    1992-12-01

    The shortage of potable water has hindered economic development in South Florida and other areas of the United States. This project, cosponsored with Florida Power Light (FPL), examines the economics of colocation of a water desalination plant with an electric power plant to take advantage of shared facilities, personnel, and equipments well as existing intake and outfall structures. In combination, these factors should reduce the cost of desalinated water. The first step in determining the viability of colocation is identification of desalination technologies best suited for dual-purpose applications in retrofits at existing fossil plants. Based on energy efficiency and commercial maturity, reverse osmosis (RO) and low-temperature multieffect distillation (LT-MED) technologies appear to be the best candidates for such application. In fact, RO provides the best economics for the plants and conditions studied. Of the emerging technologies evaluated, sodium molecular pumping and solvent extraction technologies should be further investigated for their potential in significantly reducing desalination costs.

  17. Evaluated teletherapy source library

    DOEpatents

    Cox, Lawrence J.; Schach Von Wittenau, Alexis E.

    2000-01-01

    The Evaluated Teletherapy Source Library (ETSL) is a system of hardware and software that provides for maintenance of a library of useful phase space descriptions (PSDs) of teletherapy sources used in radiation therapy for cancer treatment. The PSDs are designed to be used by PEREGRINE, the all-particle Monte Carlo dose calculation system. ETSL also stores other relevant information such as monitor unit factors (MUFs) for use with the PSDs, results of PEREGRINE calculations using the PSDs, clinical calibration measurements, and geometry descriptions sufficient for calculational purposes. Not all of this information is directly needed by PEREGRINE. It also is capable of acting as a repository for the Monte Carlo simulation history files from which the generic PSDs are derived.

  18. LIQUEFACTION EVALUATIONS AT DOE SITES

    Energy.gov [DOE]

    Liquefaction Evaluations at DOE Sites M. Lewis, M. McHood, R. Williams, B. Gutierrez October 25, 2011

  19. Performance Evaluation and Measurement Plan

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    ......... 4 PEMP ORGANIZATION Fee Determining Official ... Evaluation and Measurement Plan (PEMP) is an award fee plan containing both ...

  20. NATIONAL EVALUATIONS: SUMMARY OF RESULTS

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    EVALUATIONS: SUMMARY OF RESULTS DOE is pleased to summarize the results of two major national evaluations of the Weatherization Assistance Program (WAP or Weatherization). These evaluations were multiyear, peer-reviewed, statistically robust efforts led by Oak Ridge National Laboratory (ORNL). They are the most comprehensive, detailed analysis of the WAP and its operations ever conducted. The Retrospective Evaluation covers Program Year (PY) 2008 and is reflective of a typical year in WAP

  1. Exercise Controller and Evaluator Manual

    Directives, Delegations, and Other Requirements [Office of Management (MA)]

    1997-08-21

    This volume details the roles of controllers and evaluators in emergency exercises. Canceled by DOE G 151.1-3.

  2. Evaluation of Abuse Tolerance Improvements

    Energy.gov [DOE]

    2011 DOE Hydrogen and Fuel Cells Program, and Vehicle Technologies Program Annual Merit Review and Peer Evaluation

  3. International Energy Program Evaluation Conference

    Energy.gov [DOE]

    The International Energy Program Evaluation Conference (IEPEC) will be held in Long Beach, California, on Aug. 11-13, 2015.

  4. APEEM Components Analysis and Evaluation

    Energy.gov [DOE]

    2013 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting

  5. Header design evaluation. Final report

    SciTech Connect

    Stubenhofer, R.L.

    1993-08-01

    An evaluation was conducted of two new six-pin header designs. This evaluation consisted of designing, evaluating, procuring, and building contact module subassemblies with each of the two designs. The study was initiated as a result of the high scrap costs associated with the current product design. Two new designs were found to be feasible alternative to the current design.

  6. SECTION M_Evaluation Factors

    National Nuclear Security Administration (NNSA)

    SECTION M EVALUATION FACTORS FOR AWARD TABLE OF CONTENTS M-1 EVALUATION OF PROPOSALS......................................................................176 M-2 BASIS FOR CONTRACT AWARD...................................................................177 M-3 TECHNICAL AND MANAGEMENT CRITERIA..........................................177 M-4 COST CRITERION.............................................................................................179 Section M, Page 176 M-1 EVALUATION OF

  7. Ecological outcomes and evaluation of success in passively restored southeastern depressional wetlands.

    SciTech Connect

    De Steven, Diane; Sharitz, Rebecca R.; Barton, Christopher, D.

    2010-11-01

    Abstract: Depressional wetlands may be restored passively by disrupting prior drainage to recover original hydrology and relying on natural revegetation. Restored hydrology selects for wetland vegetation; however, depression geomorphology constrains the achievable hydroperiod, and plant communities are influenced by hydroperiod and available species pools. Such constraints can complicate assessments of restoration success. Sixteen drained depressions in South Carolina, USA, were restored experimentally by forest clearing and ditch plugging for potential crediting to a mitigation bank. Depressions were assigned to alternate revegetation methods representing desired targets of herbaceous and wet-forest communities. After five years, restoration progress and revegetation methods were evaluated. Restored hydroperiods differed among wetlands, but all sites developed diverse vegetation of native wetland species. Vegetation traits were influenced by hydroperiod and the effects of early drought, rather than by revegetation method. For mitigation banking, individual wetlands were assessed for improvement from pre-restoration condition and similarity to assigned reference type. Most wetlands met goals to increase hydroperiod, herb-species dominance, and wetland-plant composition. Fewer wetlands achieved equivalence to reference types because some vegetation targets were incompatible with depression hydroperiods and improbable without intensive management. The results illustrated a paradox in judging success when vegetation goals may be unsuited to system constraints.

  8. ARM - Evaluation Product - ARM Diagnostics for Climate Model Evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    ProductsARM Diagnostics for Climate Model Evaluation ARM Data Discovery Browse Data Documentation Use the Data File Inventory tool to view data availability at the file level. Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Evaluation Product : ARM Diagnostics for Climate Model Evaluation [ ARM research - evaluation data product ] A Python-based diagnostics package is currently being developed by the ARM Infrastructure Team to facilitate the use

  9. High Impact Technology Hub- Resources for Evaluators- Site Evaluation Checklists

    Energy.gov [DOE]

    The HIT Catalyst conducts technology demonstrations in three main phases govern demonstrations: Site Evaluation, Selection and Project Kick-Off, Measurement and Verification Scoping and Plan...

  10. High Impact Technology HQ- Resources for Evaluators- Site Evaluation Checklists

    Office of Energy Efficiency and Renewable Energy (EERE)

    The HIT Catalyst conducts technology demonstrations in three main phases govern demonstrations: Site Evaluation, Selection and Project Kick-Off, Measurement and Verification Scoping and Plan...

  11. A reevaluation of the assignment of the vibrational fundamentals and the rotational analysis of bands in the high-resolution infrared spectra of trans- and cis- 1,3,5-hexatriene

    SciTech Connect

    Craig, Norman C.; Leyden, Matthew C.; Moore, Michael C.; Patchen, Amie K.; van den Heuvel, Titus; Blake, Thomas A.; Masiello, Tony; Sams, Robert L.

    2010-07-01

    Assignments of the vibrational fundamentals of cis- and trans-1,3,5-hexatriene are reevaluated with new infrared and Raman spectra and with quantum chemical predictions of intensities and anharmonic frequencies. The rotational structure is analyzed in the high-resolution (0.0013-0.0018 cm -1) infrared spectra of three C-type bands of the trans isomer and two C-type bands of the cis isomer. The bands for the trans isomer are at 1010.96 cm-1 (v14), 900.908 cm-1 (v16), and 683.46 cm-1 (v17). Ground state (GS) rotational constants have been fitted to the combined ground state combination differences (GSCDs) for the three bands of the trans isomer. The bands for the cis isomer are at 907.70 cm-1 (v33) and 587.89 cm-1 (v35). GS rotational constants have been fitted to the combined GSCDs for the two bands of the cis isomer and compared with those obtained from microwave spectroscopy. Small inertial defects in the GSs confirm that both molecules are planar. Upper state rotational constants were fitted for all five bands.

  12. Rotary Microfilter Media Evaluation

    SciTech Connect

    Poirier, M

    2005-04-20

    Savannah River National Laboratory (SRNL) received funding from DOE EM-21, Office of Cleanup Technologies, to develop the rotary microfilter for high level radioactive service. One aspect of this project evaluated alternative filter media to select one for the 2nd generation rotary microfilter being procured as a prefilter to a small column ion exchange process. The authors conducted screening tests on a variety of filter media and pore sizes using a stirred cell followed by pilot-scale testing on a more limited number of filter media and pore sizes with a three disk rotary microfilter. These tests used 5.6 molar sodium supernate, and sludge plus monosodium titanate (MST) solids. The conclusions from this work are: (1) The 0.1 {micro} nominal TruMem{reg_sign} ceramic and the Pall PMM M050 (0.5 {micro} nominal) stainless steel filter media produced the highest flux in rotary filter testing. (2) The Pall PMM M050 media produced the highest flux of the stainless steel media tested in rotary filter testing. (3) The Pall PMM M050 media met filtrate quality requirements for the rotary filter. (4) The 0.1 {micro} TruMem{reg_sign} and 0.1 {micro} Pall PMM media met filtrate quality requirements as well. (5) The Pall PMM M050 media produced comparable flux to the 0.1 {micro} TruMem{reg_sign} media, and proved more durable and easier to weld. Based on these test results, the authors recommend Pall PMM M050 filter media for the 2nd generation rotary microfilter.

  13. What happened after the evaluation?

    SciTech Connect

    Bennett, C L

    1999-03-12

    An ergonomics program including a ergonomic computer workstation evaluations at a research and development facility was assessed three years after formal implementation. As part of the assessment, 53 employees who had been subjects of computer workstation evaluations were interviewed. The documented reports (ergonomic evaluation forms) of the ergonomic evaluations were used in the process of selecting the interview subjects. The evaluation forms also provided information about the aspects of the computer workstation that were discussed and recommended as part of the evaluation, although the amount of detail and completeness of the forms varied. Although the results were mixed and reflective of the multivariate psychosocial factors affecting employees working in a large organization, the findings led to recommendations for improvements of the program.

  14. State Energy Program Retrospective Evaluation

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    of a major national evaluation of the State Energy Program (SEP), under the Office of Energy Efficiency and Renewable Energy. The Retrospective Evaluation of SEP's Program Year (PY) 2008, a typical year in SEP operations, was a multiyear, peer-reviewed, statistically robust effort led by Oak Ridge National Laboratory (ORNL). It is the most comprehensive, detailed analysis ever conducted of SEP. The purpose of the evaluation was to develop independent estimates of key program outcomes, including:

  15. Hawaii-Okinawa Building Evaluations

    SciTech Connect

    Metzger, I.; Salasovich, J.

    2013-05-01

    NREL conducted energy evaluations at the Itoman City Hall building in Itoman, Okinawa Prefecture, Japan, and the Hawaii State Capitol building in Honolulu, Hawaii. This report summarizes the findings from the evaluations, including the best practices identified at each site and opportunities for improving energy efficiency and renewable energy. The findings from this evaluation are intended to inform energy efficient building design, energy efficiency technology, and management protocols for buildings in subtropical climates.

  16. Sandia National Laboratory Performance Evaluations | National Nuclear

    National Nuclear Security Administration (NNSA)

    Security Administration | (NNSA) Sandia National Laboratory Performance Evaluations FY 2016 FY 2016 Performance Evaluation Plan, Sandia Corporation FY 2015 FY 2015 Performance Evaluation Report, Sandia Corporation FY 2015 Performance Evaluation Report, Fee Determination Letter, Sandia Corporation FY 2015 Performance Evaluation Plan, Sandia Corporation FY 2014 FY 2014 Performance Evaluation Report, Sandia Corporation FY 2014 Performance Evaluation Report, Fee Determination Letter, Sandia

  17. PAE Evaluation Portfolio Peer Review

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    ... Relatedly, the research community capable of conducting ... in the country in 2001 by the American Journal of Evaluation. ... a Ph.D. in Educational Psychology, Measurement and ...

  18. Performance Evaluation and Measurement Plan

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    and Measurement Plan Mission Support Contract Section J - August 2016 Contract No. ... Performance Evaluation and Measurement Plan 1. INTRODUCTION This Performance ...

  19. SECTION M_Evaluation Factors

    National Nuclear Security Administration (NNSA)

    the policies and procedures in Federal Acquisition Regulation (FAR) Part 15 and Department of Energy Acquisition Regulation (DEAR) Part 915. The Government will evaluate ...

  20. International Energy Program Evaluation Conference

    Energy.gov [DOE]

    The International Energy Program Evaluation Conference (IEPEC) is a three-day conference for energy program implementers, academic researchers, and state, local, and national energy representatives.

  1. State Energy Program National Evaluation

    Energy.gov [DOE]

    The Weatherization and Intergovernmental Programs Office authorized the Oak Ridge National Laboratory to implement a national evaluation of the State Energy Program.

  2. HAB 2008 Self-Evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    and agency evaluations combined Total responses 27 RESULTS OVERALL RESPONDENT DEMOGRAPHICS (PERCENT BY COMMITTEE) HAB Committee 58% River and Plateau 63% Tank Waste 33%...

  3. Sandia Energy - Evaluating Rooftop Strength for PV

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Evaluating Rooftop Strength for PV Home Stationary Power Energy Conversion Efficiency Solar Energy Photovoltaics Evaluating Rooftop Strength for PV Evaluating Rooftop Strength for...

  4. Recommendation 212: Evaluate additional storage and disposal...

    Office of Environmental Management (EM)

    2: Evaluate additional storage and disposal options Recommendation 212: Evaluate additional storage and disposal options The ORSSAB encourages DOE to evaluate additional storage...

  5. Update on Status of SEP National Evaluation

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Update for State Energy Advisory Board on Status of SEP National Evaluation Martin ... Evaluation Briefing General Approach for SEP National Evaluation * Sample 82 ...

  6. Evaluation of Automated Model Calibration Techniques for Residential Building Energy Simulation

    SciTech Connect

    and Ben Polly, Joseph Robertson; Polly, Ben; Collis, Jon

    2013-09-01

    This simulation study adapts and applies the general framework described in BESTEST-EX (Judkoff et al 2010) for self-testing residential building energy model calibration methods. BEopt/DOE-2.2 is used to evaluate four mathematical calibration methods in the context of monthly, daily, and hourly synthetic utility data for a 1960's-era existing home in a cooling-dominated climate. The home's model inputs are assigned probability distributions representing uncertainty ranges, random selections are made from the uncertainty ranges to define "explicit" input values, and synthetic utility billing data are generated using the explicit input values. The four calibration methods evaluated in this study are: an ASHRAE 1051-RP-based approach (Reddy and Maor 2006), a simplified simulated annealing optimization approach, a regression metamodeling optimization approach, and a simple output ratio calibration approach. The calibration methods are evaluated for monthly, daily, and hourly cases; various retrofit measures are applied to the calibrated models and the methods are evaluated based on the accuracy of predicted savings, computational cost, repeatability, automation, and ease of implementation.

  7. Evaluation of Automated Model Calibration Techniques for Residential Building Energy Simulation

    SciTech Connect

    Robertson, J.; Polly, B.; Collis, J.

    2013-09-01

    This simulation study adapts and applies the general framework described in BESTEST-EX (Judkoff et al 2010) for self-testing residential building energy model calibration methods. BEopt/DOE-2.2 is used to evaluate four mathematical calibration methods in the context of monthly, daily, and hourly synthetic utility data for a 1960's-era existing home in a cooling-dominated climate. The home's model inputs are assigned probability distributions representing uncertainty ranges, random selections are made from the uncertainty ranges to define 'explicit' input values, and synthetic utility billing data are generated using the explicit input values. The four calibration methods evaluated in this study are: an ASHRAE 1051-RP-based approach (Reddy and Maor 2006), a simplified simulated annealing optimization approach, a regression metamodeling optimization approach, and a simple output ratio calibration approach. The calibration methods are evaluated for monthly, daily, and hourly cases; various retrofit measures are applied to the calibrated models and the methods are evaluated based on the accuracy of predicted savings, computational cost, repeatability, automation, and ease of implementation.

  8. SECTION M_Evaluation Factors

    National Nuclear Security Administration (NNSA)

    EVALUATION OF PROPOSALS................................................................2 M-2 BASIS FOR CONTRACT AWARD.............................................................3 M-3 TECHNICAL AND MANAGEMENT CRITERIA...........................................3 M-4 COST CRITERION.................................................................................5 Section M, Page 2 M-1 EVALUATION OF PROPOSALS (a) This acquisition will be conducted using the policies and procedures in Federal

  9. Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio)

    SciTech Connect

    Aluru, Neelakanteswar; Kuo, Elaine; Helfrich, Lily W.; Karchner, Sibel I.; Linney, Elwood A.; Pais, June E.; Franks, Diana G.

    2015-04-15

    DNA methylation is one of the most important epigenetic modifications involved in the regulation of gene expression. The DNA methylation reaction is catalyzed by DNA methyltransferases (DNMTs). Recent studies have demonstrated that toxicants can affect normal development by altering DNA methylation patterns, but the mechanisms of action are poorly understood. Hence, we tested the hypothesis that developmental exposure to TCDD affects dnmt gene expression patterns. Zebrafish embryos were exposed to 5 nM TCDD for 1 h from 4 to 5 h post-fertilization (hpf) and sampled at 12, 24, 48, 72, and 96 hpf to determine dnmt gene expression and DNA methylation patterns. We performed a detailed analysis of zebrafish dnmt gene expression during development and in adult tissues. Our results demonstrate that dnmt3b genes are highly expressed in early stages of development, and dnmt3a genes are more abundant in later stages. TCDD exposure upregulated dnmt1 and dnmt3b2 expression, whereas dnmt3a1, 3b1, and 3b4 are downregulated following exposure. We did not observe any TCDD-induced differences in global methylation or hydroxymethylation levels, but the promoter methylation of aryl hydrocarbon receptor (AHR) target genes was altered. In TCDD-exposed embryos, AHR repressor a (ahrra) and c-fos promoters were differentially methylated. To characterize the TCDD effects on DNMTs, we cloned the dnmt promoters with xenobiotic response elements and conducted AHR transactivation assays using a luciferase reporter system. Our results suggest that ahr2 can regulate dnmt3a1, dnmt3a2, and dnmt3b2 expression. Overall, we demonstrate that developmental exposure to TCDD alters dnmt expression and DNA methylation patterns. - Highlights: • TCDD altered the dnmt expression in a gene and developmental time-specific manner. • TCDD hypermethylated ahrra and hypomethylated c-fos proximal promoter regions. • Functional analysis suggests that ahr2 can regulate dnmt3a1, 3a2, and 3b2 expression. • Dnmt

  10. Geothermal Electricity Technology Evaluation Model (GETEM) Development...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Electricity Technology Evaluation Model (GETEM) Development Geothermal Electricity Technology Evaluation Model (GETEM) Development Project objective: Provide a tool for estimating...

  11. Data Aggregation Strategies for Evaluation and Reporting

    Energy.gov [DOE]

    BetterBuildings: Data and Evaluation Peer Exchange Call: Data Aggregation Strategies for Evaluation and Reporting, June 9, 2011.

  12. RELAP5-3D Developmental Assessment: Comparison of Versions 4.3.4i and 4.2.1i

    SciTech Connect

    Bayless, Paul David

    2015-10-01

    Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code using versions 4.3.4i and 4.2.1i. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions changed between these two code versions and can be used to identify cases in which the assessment judgment may need to be changed in Volume III of the code manual. Changes to the assessment judgments made after reviewing all of the assessment cases are also provided.

  13. RELAP5-3D Developmental Assessment: Comparison of Versions 4.2.1i and 4.1.3i

    SciTech Connect

    Paul D. Bayless

    2014-06-01

    Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code using versions 4.2.1i and 4.1.3i. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions changed between these two code versions and can be used to identify cases in which the assessment judgment may need to be changed in Volume III of the code manual. Changes to the assessment judgments made after reviewing all of the assessment cases are also provided.

  14. RELAP5-3D Developmental Assessment: Comparison of Versions 4.0.3is and 2.4.2is

    SciTech Connect

    Paul D. Bayless

    2012-09-01

    Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code using versions 4.0.3is and 2.4.2is. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions changed between these two code versions and can be used to identify cases in which the assessment judgment may need to be changed in Volume III of the code manual. Changes to the assessment judgments made after reviewing all of the assessment cases are also provided.

  15. Enhanced sludge washing evaluation plan

    SciTech Connect

    Jensen, R.D.

    1994-09-01

    The Tank Waste Remediation System (TWRS) Program mission is to store, treat, and immobilize highly radioactive Hanford Site waste (current and future tank waste and the strontium/cesium capsules) in an environmentally sound, safe, and cost-effective manner. The scope of the TWRS Waste Pretreatment Program is to treat tank waste and separate that waste into HLW and LLW fractions and provide additional treatment as required to feed LLW and HLW immobilization facilities. Enhanced sludge washing was chosen as the baseline process for separating Hanford tank waste sludge. Section 1.0 briefly discusses the purpose of the evaluation plan and provides the background that led to the choice of enhanced sludge washing as the baseline process. Section 2.0 provides a brief summary of the evaluation plan details. Section 3.0 discusses, in some detail, the technical work planned to support the evaluation of enhanced sludge washing. Section 4.0 briefly discusses the potential important of policy issues to the evaluation. Section 5.0 discusses the methodology to be used in the evaluation process. Section 6.0 summarizes the milestones that have been defined to complete the enhanced sludge washing evaluation and provides a summary schedule to evaluate the performance of enhanced sludge washing. References are identified in Section 7.0, and additional schedule and milestone information is provided in the appendices.

  16. Use of genomic data in risk assessment case study: II. Evaluation of the dibutyl phthalate toxicogenomic data set

    SciTech Connect

    Euling, Susan Y.; White, Lori D.; Kim, Andrea S.; Sen, Banalata; Wilson, Vickie S.; Keshava, Channa; Keshava, Nagalakshmi; Hester, Susan; Ovacik, Meric A.; Ierapetritou, Marianthi G.; Androulakis, Ioannis P.; Gaido, Kevin W.

    2013-09-15

    An evaluation of the toxicogenomic data set for dibutyl phthalate (DBP) and male reproductive developmental effects was performed as part of a larger case study to test an approach for incorporating genomic data in risk assessment. The DBP toxicogenomic data set is composed of nine in vivo studies from the published literature that exposed rats to DBP during gestation and evaluated gene expression changes in testes or Wolffian ducts of male fetuses. The exercise focused on qualitative evaluation, based on a lack of available doseresponse data, of the DBP toxicogenomic data set to postulate modes and mechanisms of action for the male reproductive developmental outcomes, which occur in the lower dose range. A weight-of-evidence evaluation was performed on the eight DBP toxicogenomic studies of the rat testis at the gene and pathway levels. The results showed relatively strong evidence of DBP-induced downregulation of genes in the steroidogenesis pathway and lipid/sterol/cholesterol transport pathway as well as effects on immediate early gene/growth/differentiation, transcription, peroxisome proliferator-activated receptor signaling and apoptosis pathways in the testis. Since two established modes of action (MOAs), reduced fetal testicular testosterone production and Insl3 gene expression, explain some but not all of the testis effects observed in rats after in utero DBP exposure, other MOAs are likely to be operative. A reanalysis of one DBP microarray study identified additional pathways within cell signaling, metabolism, hormone, disease, and cell adhesion biological processes. These putative new pathways may be associated with DBP effects on the testes that are currently unexplained. This case study on DBP identified data gaps and research needs for the use of toxicogenomic data in risk assessment. Furthermore, this study demonstrated an approach for evaluating toxicogenomic data in human health risk assessment that could be applied to future chemicals

  17. Program Evaluation: Informed Decisions | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Why, What, & When to Evaluate » Program Evaluation: Informed Decisions Program Evaluation: Informed Decisions Evaluation activities support decision-making that can contribute to efficient and effective management of programs. Evaluative information should be available to inform decisions made during the critical planning, budgeting, analysis, implementation, and benefits reporting/ communications cycles of the program. Program evaluation can provide essential information to inform

  18. SES CANDIDATE DEVELOPMENT PROGRAM

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    3 (11-03) SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP) Developmental Assignment Opportunity DATE: NAME OF SES CANDIDATE: TITLE: ASSIGNMENT NUMBER: ASSIGNMENT BEGINS: ENDS: TELEPHONE NUMBER: FAX NUMBER: EMAIL ADDRESS: ASSIGNMENT LOCATION HOST ORGANIZATION: PURPOSE OF ASSIGNMENT: ASSIGNMENT POSITION: ASSIGNMENT DUTIES: EXECUTIVE COR QUALIFICATIONS TO BE ADDRESSED: OFFICE ADDRESS: TELEPHONE NUMBER: FAX NUMBER: E-MAIL ADDRESS: 1 U.S. DEPARTMENT OF ENERGY SENIOR EXECUTIVE SERVICE

  19. The effects of toxicants on early developmental stages of two marine organisms: Giant kelp, Macrocystis pyrifera, and California mussels, Mytilus californianus

    SciTech Connect

    Garman, G.D.

    1993-01-01

    Early developmental events of the reproductive (gametophytic) stage were the focus of assessment of toxicant effects on Macrocystis pyrifera. Developing gametophytes were exposed to produced water (PW), an aqueous waste from oil production activities, and two common metal contaminants of coastal environments, arsenic (As) and copper (Cu). The developmental processes assessed were zoospore germination, germ tube elongation, and nuclear migration (determined by epifluorescence microscopy and the DNA fluorochrome, Hoechst 33342). Nuclear migration, encompassing replication and division of nuclear material into two nuclei with subsequent translocation of one of the nuclei, was determined to be the process most responsive to the toxicants. To further explore the role of metabolism and pH in the completion of early nuclear events, developing M. pyrifera gametophytes were exposed to arsenic (sodium arsenate) and CCCP (carbonyl cyanide m-chlorophenylhydrazone) as well as a permeant weak acid and weak base. Exposure to As at time points coincident with DNA synthesis and nuclear division/translocation followed by assessment of DNA levels and nuclear translocation showed that both DNA synthesis and nuclear division/translocation were inhibited. Amelioration of As effects by phosphate enrichment was also observed, lending support to the hypothesis that As, as arsenate, disrupts energy metabolism in cells due to competition with phosphate. Both CCCP and the permeant weak base, NH[sub 4]Cl, inhibited nuclear division/translocation, suggesting that intracellular alkalinization inhibits this microtubule-mediated process. In an investigation of the effects of PW on a representative invertebrate species, California mussels (Mytilus californianus) were place at 1, 10, 100, and 1000 m distances from the outfall of an oil processing plant to determine growth and reproduction in exposed adult mussels as well as effects on their offspring.

  20. Advanced Vehicle Testing and Evaluation

    SciTech Connect

    Garetson, Thomas

    2013-03-31

    The objective of the United States (U.S.) Department of Energy's (DOEs) Advanced Vehicle Testing and Evaluation (AVTE) project was to provide test and evaluation services for advanced technology vehicles, to establish a performance baseline, to determine vehicle reliability, and to evaluate vehicle operating costs in fleet operations.Vehicles tested include light and medium-duty vehicles in conventional, hybrid, and all-electric configurations using conventional and alternative fuels, including hydrogen in internal combustion engines. Vehicles were tested on closed tracks and chassis dynamometers, as well as operated on public roads, in fleet operations, and over prescribed routes. All testing was controlled by procedures developed specifically to support such testing.

  1. Petrophysical evaluation of subterranean formations

    DOEpatents

    Klein, James D; Schoderbek, David A; Mailloux, Jason M

    2013-05-28

    Methods and systems are provided for evaluating petrophysical properties of subterranean formations and comprehensively evaluating hydrate presence through a combination of computer-implemented log modeling and analysis. Certain embodiments include the steps of running a number of logging tools in a wellbore to obtain a variety of wellbore data and logs, and evaluating and modeling the log data to ascertain various petrophysical properties. Examples of suitable logging techniques that may be used in combination with the present invention include, but are not limited to, sonic logs, electrical resistivity logs, gamma ray logs, neutron porosity logs, density logs, NRM logs, or any combination or subset thereof.

  2. Natural Areas Analysis and Evaluation: Oak Ridge Reservation

    SciTech Connect

    Baranski, Micahel J

    2009-11-01

    EXECUTIVE SUMMARY The Oak Ridge Reservation, encompassing 33,639 acres in the Valley and Ridge Physiographic Province of East Tennessee, has long been known for its unfragmented forests and high biodiversity. Many areas on the Reservation have been recognized as important natural areas, but no comprehensive treatment has been performed to evaluate the relative significance and importance of these areas compared to each other. The present study was conducted to develop a set of guidelines for evaluating the natural value of specific areas, to evaluate all the terrestrial areas that are currently delineated, and to rank all areas according to their relative biodiversity importance. All available data, reports and site-specific information relevant to Reservation lands, including Tennessee Division of Natural Areas database information, were evaluated and field work was conducted. Methodologies and criteria for assessment and evaluation of areas were developed; categories of criteria were devised; and a ranking system for evaluation of natural areas was produced. There were 70 areas evaluated during the study. The system is flexible, dynamic and easily revised to reflect updated and new information and interpretations. Eight categories of evaluation factors were established and used to characterize each site. These were the following: size of area, number or status taxa present, number of Endangered and Threatened taxa present, rarity of the Endangered and Threatened taxa on the Reservation, community diversity, site integrity and quality, disturbance and threat levels, and other significant features and factors. Each category generally consisted of a 5-point ranking scale from 0-4, allowing for a possible composite score of 32, with higher ranked, more important, sites attaining higher scores. Highly ranked sites are representative of regional natural diversity; contain outstanding natural features, communities or geology and/or very rare taxa or other elements; are

  3. PAE Evaluation Portfolio Peer Review

    Energy.gov [DOE]

    This is a report from the Peer Review Panel on activities within the Planning, Analysis and Evaluation Unit of the Office of Planning, Budget and Analysis, Office of Energy Efficiency and Renewable Energy, U.S. Department of Energy.

  4. Open Government Plan Self Evaluation

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Government Plan Self Evaluation Page 1 of 3 NAME OF AGENCY: Department of Energy NAME OF ... each of the criteria as follows: Red (R) - plan does not satisfy the requirement Yellow ...

  5. PAE Evaluation Portfolio Peer Review

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    ... She has lectured on performance measurement and public program evaluation in Ukraine, Brazil, Egypt, Taiwan, and the UK. Dr. Newcomer earned a B.S. in education and an M.A. in ...

  6. Nuclear Explosive Safety Evaluation Processes

    Directives, Delegations, and Other Requirements [Office of Management (MA)]

    2009-04-14

    This Manual provides supplemental details to support the nuclear explosive safety evaluation requirement of DOE O 452.2D, Nuclear Explosive Safety. Does not cancel other directives. Admin Chg 1, 7-10-13.

  7. Data and Evaluation Kickoff Call

    Energy.gov [DOE]

    Better Buildings Data and Evaluation Peer Exchange Kick­off Call to Discuss Key Topics for Peer­ to ­Peer Discussions, Call Slides and Discussion Summary, May 12, 2011.

  8. Program Evaluation: Program Life Cycle

    Energy.gov [DOE]

    In general, different types of evaluation are carried out over different parts of a program's life cycle (e.g., Creating a program, Program is underway, or Closing out or end of program)....

  9. Program Evaluation: Strategic Planning | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Why, What, & When to Evaluate » Program Evaluation: Strategic Planning Program Evaluation: Strategic Planning One way to have useful and cost-effective evaluations is to strategically plan evaluation activity so it supports management activity cycles for planning, budgeting, analysis, program implementation, and benefits reporting and communication. In this way, evaluations generate information to feed into critical decision processes and continuous improvement. Planning evaluations

  10. Evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    ... Rep., 1987. 15 R. Perez, "Dynamic global to direct conversion models," ASHRAE Transactions Research Series, pp. 154-168, 1992. 16 R. Posadillo and R. L opez Luque, "Hourly ...

  11. LNG Safety Assessment Evaluation Methods

    SciTech Connect

    Muna, Alice Baca; LaFleur, Angela Christine

    2015-05-01

    Sandia National Laboratories evaluated published safety assessment methods across a variety of industries including Liquefied Natural Gas (LNG), hydrogen, land and marine transportation, as well as the US Department of Defense (DOD). All the methods were evaluated for their potential applicability for use in the LNG railroad application. After reviewing the documents included in this report, as well as others not included because of repetition, the Department of Energy (DOE) Hydrogen Safety Plan Checklist is most suitable to be adapted to the LNG railroad application. This report was developed to survey industries related to rail transportation for methodologies and tools that can be used by the FRA to review and evaluate safety assessments submitted by the railroad industry as a part of their implementation plans for liquefied or compressed natural gas storage ( on-board or tender) and engine fueling delivery systems. The main sections of this report provide an overview of various methods found during this survey. In most cases, the reference document is quoted directly. The final section provides discussion and a recommendation for the most appropriate methodology that will allow efficient and consistent evaluations to be made. The DOE Hydrogen Safety Plan Checklist was then revised to adapt it as a methodology for the Federal Railroad Administration’s use in evaluating safety plans submitted by the railroad industry.

  12. Comparative pharmacokinetic study of the role of gender and developmental differences in occupational and environmental exposure to benzene. Master's thesis

    SciTech Connect

    Brown, E.A.

    1994-09-01

    The purpose of this study is two-fold. First, it shows that physiological differences between men and women result in gender-specific exposures with respect to benzene. Second, it assesses the potential for a lactating woman's occupational and personal benzene exposure to impact a nursing infant's exposure, highlighting the possibility of subjecting an infant to the effects of industrial chemicals via breast feeding. This study employs physiologically based pharmacokinetic (PBPK) modeling to investigate the influence of physiological parameters and to evaluate the ability of inhaled benzene to transfer from mother to infant through breastmilk. The models are run through scenarios that simulate occupational, smoking, and background exposures. The gender comparison is facilitated by a sensitivity analysis. The blood/air partition coefficient and maximum velocity of metabolism were found to substantially impact model output. These values were both higher in women and caused an increase in the percentage of benzene metabolized in all of the exposure scenarios. The study of lactating women and infants is essentially theoretical. There is evidence that over 65% of an infant's benzene exposure can be attributed to contaminated breastmilk. A large portion of the ingested exposure can be eliminated by adjusting the mother's working or nursing schedule. Benzene, Physiologically based pharmacokinetics, PBPK.

  13. Weatherization Assistance Program National Evaluation | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Energy Weatherization Assistance Program National Evaluation Weatherization Assistance Program National Evaluation The Weatherization and Intergovernmental Programs Office authorized the Oak Ridge National Laboratory to implement the national evaluation of the Weatherization Assistance Program. This evaluation addressed energy and cost savings, non-energy benefits, program cost-effectiveness, and program operations for program year 2008, called the Retrospective Evaluation, and for program

  14. Report of the Peer Review Panel on the early site suitability evaluation of the Potential Repository Site at Yucca Mountain, Nevada; Yucca Mountain Site Characterization Project

    SciTech Connect

    1992-01-01

    The US Department of Energy (DOE) Yucca mountain Site Characterization Project Office (YMPO) assigned Science Applications International Corporation (SAIC), the Technical and Management Support Services (T&MSS) contractor to the YmPo, the task of conducting an Early Site Suitability Evaluation (ESSE) of the Yucca mountain site as a potential site for a high-level radioactive waste repository. First, the assignment called for the development of a method to evaluate a single site against the DOE General Guidelines for Recommendation of Sites for Nuclear Waste Repositories, 10 CFR Part 960. Then, using this method, an evaluation team, the ESSE Core Team, of senior YMP scientists, engineers, and technical experts, evaluated new information obtained about the site since publication of the final Environmental Assessment (DOE, 1986) to determine if new suitability/unsuitability findings could be recommended. Finally, the Core Team identified further information and analyses needed to make final determinations for each of the guidelines. As part of the task, an independent peer review of the ESSE report has been conducted. Expertise was solicited that covered the entire spectrum of siting guidelines in 10 CFR Part 960 in order to provide a complete, in-depth critical review of the data evaluated and cited in the ESSE report, the methods used to evaluate the data, and the conclusions and recommendations offered by the report. Fourteen nationally recognized technical experts (Table 2) served on the Peer Review Panel. The comments from the Panel and the responses prepared by the ESSE Core Team, documented on formal Comment Response Forms, constitute the body of this document.

  15. FY08 VPP Program Evaluation

    SciTech Connect

    Dossett, Sharon D.

    2008-01-01

    The Voluntary Protection Program (VPP) is a recognized third-party certification of worker safety and health program excellence, based on industry best practices that focus on management leadership and employee involvement, as well as other safety and health program elements. This Pacific Northwest National Laboratory (PNNL) VPP Program Evaluation is the FY-2008 report of the PNNL VPP Steering Committee regarding the status of VPP at PNNL. It is an update of the previous annual report dated January, 2007 and was completed in January 2008. An annual evaluation of the status of VPP is required of all sites that participate in the DOE-VPP. This report provides a detailed summary of the PNNL VPP Steering Committee’s evaluation of program performance and documents both strengths and improvement opportunities related to the various aspects of the VPP model.

  16. Air Sampling System Evaluation Template

    Energy Science and Technology Software Center

    2000-05-09

    The ASSET1.0 software provides a template with which a user can evaluate an Air Sampling System against the latest version of ANSI N13.1 "Sampling and Monitoring Releases of Airborne Radioactive Substances from the Stacks and Ducts of Nuclear Facilities". The software uses the ANSI N13.1 PIC levels to establish basic design criteria for the existing or proposed sampling system. The software looks at such criteria as PIC level, type of radionuclide emissions, physical state ofmore » the radionuclide, nozzle entrance effects, particulate transmission effects, system and component accuracy and precision evaluations, and basic system operations to provide a detailed look at the subsystems of a monitoring and sampling system/program. A GAP evaluation can then be completed which leads to identification of design and operational flaws in the proposed systems. Corrective measures can then be limited to the GAPs.« less

  17. ARM - Evaluation Product - Cloud Type

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    ProductsCloud Type ARM Data Discovery Browse Data Documentation Use the Data File Inventory tool to view data availability at the file level. Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Evaluation Product : Cloud Type [ ARM research - evaluation data product ] This data product determines a cloud type using cloud boundaries derived from vertically pointing lidar and radar clouds. It uses Active Remotely Sensed Cloud Locations (ARSCL) data as

  18. Technology Validation: Fuel Cell Bus Evaluations | Department...

    Energy.gov [DOE] (indexed site)

    8eudy.pdf (1.89 MB) More Documents & Publications Technology Validation: Fuel Cell Bus Evaluations Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for the ...

  19. Program Course Corrections Based on Evaluation Results

    Energy.gov [DOE]

    Better Buildings Neighborhood Program Data and Evaluation Peer Exchange Call: Program Course Corrections Based on Evaluation Results, Call Slides and Discussion Summary, April 12, 2012, This call discussed using evaluation results as the basis for course corrections.

  20. Pantex Plant Performance Evaluations | National Nuclear Security

    National Nuclear Security Administration (NNSA)

    Administration | (NNSA) Pantex Plant Performance Evaluations FY 2016 FY 2016 Performance Evaluation Plan, Consolidated Nuclear Security, LLC FY 2015 FY 2015 Performance Evaluation Report, Consolidated Nuclear Security, LLC FY 2015 Performance Evaluation Report, Fee Determination Letter, Consolidated Nuclear Security, LLC FY 2015 Performance Evaluation Plan, Consolidated Nuclear Security, LLC FY 2014 FY 2014 Performance Evaluation Report, Babcock & Wilcox Technical Services Pantex, LLC FY

  1. Nuclear Explosive Safety Evaluation Processes

    Directives, Delegations, and Other Requirements [Office of Management (MA)]

    2009-04-14

    This Manual provides supplemental details to support the nuclear explosive safety (NES) evaluation requirement of Department of Energy (DOE) Order (O) 452.2D, Nuclear Explosive Safety, dated 4/14/09. Admin Chg 1, dated 7-10-13, cancels DOE M 452.2-2.

  2. NDOT - Application Information for Evaluating Annual Permit ...

    OpenEI (Open Energy Information) [EERE & EIA]

    - Application Information for Evaluating Annual Permit Jump to: navigation, search OpenEI Reference LibraryAdd to library Form: NDOT - Application Information for Evaluating Annual...

  3. Research, Development, Test, and Evaluation | National Nuclear...

    National Nuclear Security Administration (NNSA)

    About Our Programs Defense Programs Research, Development, Test, and Evaluation ... The Office of Research, Development, Test, and Evaluation directs research, development, ...

  4. Program Evaluation: Information Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Information Resources Program Evaluation: Information Resources You may want to speak to an evaluator or performance measurement professional personally, look up the definition of ...

  5. Evaluation Report: IG-0567 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    7 Evaluation Report: IG-0567 September 9, 2002 The Department's Unclassified Cyber Security Program 2002 PDF icon Evaluation Report: IG-0567 More Documents & Publications ...

  6. Evaluation Report: IG-0569 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Evaluation Report: IG-0569 September 13, 2002 The Federal Energy Regulatory Commission's Unclassified Cyber Security Program Evaluation Report on "The Federal Energy Regulatory ...

  7. Population Sensitivity Evaluation of Two Candidate Locations...

    Energy.gov [DOE] (indexed site)

    Population Sensitivity Evaluation of Two Candidate Locations for Possible Small Modular Reactor Siting (3.84 MB) More Documents & Publications Evaluation of Proposed Hampton Roads ...

  8. International Energy Policies & Programmes Evaluation Conference

    Office of Energy Efficiency and Renewable Energy (EERE)

    The purpose of the conference is to provide a forum for the presentation, critique and discussion of objective evaluations, as well as for experience sharing about evaluation practices.

  9. Plutonium-238 Production Chemical Processing Evaluations (Conference...

    Office of Scientific and Technical Information (OSTI)

    Conference: Plutonium-238 Production Chemical Processing Evaluations Citation Details In-Document Search Title: Plutonium-238 Production Chemical Processing Evaluations Authors: ...

  10. Develop & Evaluate Materials & Additives that Enhance Thermal...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Evaluate Materials & Additives that Enhance Thermal & Overcharge Abuse Develop & Evaluate Materials & Additives that Enhance Thermal & Overcharge Abuse 2011 DOE Hydrogen and Fuel ...

  11. Helping Policymakers Evaluate Distributed Wind Options | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Helping Policymakers Evaluate Distributed Wind Options Helping Policymakers Evaluate Distributed Wind Options April 18, 2013 - 12:00am Addthis With EERE support, eFormative Options...

  12. Independent Oversight Focused Safety Management Evaluation, Idaho...

    Energy.gov [DOE] (indexed site)

    January 2001 Focused Safety Management Evaluation of the Idaho National Engineering and Environmental Laboratory This report provides the results of an evaluation of the integrated...

  13. Measure and Evaluate Institutional Change for Sustainability

    Energy.gov [DOE]

    The measure and evaluation step is crucial to ensure that institutional change efforts produce successful results in meeting sustainability goals. To measure success, an evaluation is needed.

  14. Postdoctoral Performance Evaluation | Argonne National Laboratory

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Performance Evaluation The Postdoctoral Performance Evaluation form (ANL-699) should be filled at the time of renewal and upload it in the XINK system. Microsoft Office document...

  15. GETEM -Geothermal Electricity Technology Evaluation Model | Department...

    Energy Saver

    GETEM -Geothermal Electricity Technology Evaluation Model GETEM -Geothermal Electricity Technology Evaluation Model A guide to providing input to GETEM, the Geothermal Electricity ...

  16. Evaluating Solar Energy Sites | Department of Energy

    Energy.gov [DOE] (indexed site)

    Evaluating the solar energy site is the third step in planning for a federal site solar project. This section outlines the detailed information needed to evaluate specific sites ...

  17. SESCDP Supervisor's Evaluation of Candidate's Performance During...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    objectives, an overall rating of the candidate's performance, evaluation of executive core qualifications PDF icon SESCDP Supervisor's Evaluation of Candidate's Performance ...

  18. Building America Technology Solutions Case Study: Evaluation...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Evaluation of Passive Vents in New-Construction Multifamily Buildings Building America Technology Solutions Case Study: Evaluation of Passive Vents in New-Construction Multifamily ...

  19. Vehicle Technologies Office: AVTA - Evaluating National Parks...

    Office of Environmental Management (EM)

    AVTA - Evaluating National Parks and Forest Service Fleets for Plug-in Electric Vehicles Vehicle Technologies Office: AVTA - Evaluating National Parks and Forest Service Fleets for ...

  20. Building America Program Evaluation, Harvard University, Volume...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    1, 2004 Building America Program Evaluation, Harvard University, Volume 1, 2004 Building America Program Evaluation, Volume I: Main Report, prepared by Energy Technology Innovation ...

  1. Building America Program Evaluation, Harvard University, Volume...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    2, 2004 Building America Program Evaluation, Harvard University, Volume 2, 2004 Building America Program Evaluation, Volume II: Appendices, prepared by: Energy Technology ...

  2. Former Workers Medical Facilities with Experience Evaluating...

    Energy Saver

    Former Workers Medical Facilities with Experience Evaluating Chronic Beryllium Disease Former Workers Medical Facilities with Experience Evaluating Chronic Beryllium Disease April...

  3. SEP National Evaluation Update for STEAB

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    design began in late 2008 Study scope and design reviewed by Network Committee of SEO representatives and Peer Review Panel of evaluation experts Independent evaluation ...

  4. Benefits of Evaluation, Measurement, and Verification | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Benefits of Evaluation, Measurement, and Verification Benefits of Evaluation, Measurement, and Verification This document provides information about the benefits of performing ...

  5. Super Efficient Refrigerator Program (SERP) evaluation. Volume 1: Process evaluation

    SciTech Connect

    Sandahl, L.J.; Ledbetter, M.R.; Chin, R.I.; Lewis, K.S.; Norling, J.M.

    1996-01-01

    The Pacific Northwest National Laboratory (PNNL) conducted this study for the US Department of Energy (DOE) as part of the Super Efficient Refrigerator Program (SERP) Evaluation. This report documents the SERP formation and implementation process, and identifies preliminary program administration and implementation issues. The findings are based primarily on interviews with those familiar with the program, such as utilities, appliance manufacturers, and SERP administrators. These interviews occurred primarily between March and April 1995, when SERP was in the early stages of program implementation. A forthcoming report will estimate the preliminary impacts of SERP within the industry and marketplace. Both studies were funded by DOE at the request of SERP Inc., which sought a third-party evaluation of its program.

  6. 1994 Ergonomics Program Quality Evaluation

    SciTech Connect

    Longbotham, L.; Miller, D.P.

    1995-06-01

    A telephone survey was conducted to evaluate the quality of service provided to the primary customers of the Corporate Ergonomics Group (CEG). One hundred clients who received services between October 1993 and June 1994 were asked questions on their expectations, implementation of ergonomic recommendations, follow-ups, time required, productivity improvements, symptom alleviation, and satisfaction. Suggestions on how processes could be improved were also solicited. In general, recommendations are being implemented, worksite evaluations are going smoothly, and customers are satisfied with the process. The CEG was pleased to learn that half of the people who implemented recommendations experienced improvements in productivity, and four out of five symptomatic customers experienced partial or complete relief. Through analysis of the data and by studying clients` suggestions for process improvement, the CEG has developed a strategy for changing and improving current procedures and practices. These plans can be found in the last section of this report.

  7. Methodology for flammable gas evaluations

    SciTech Connect

    Hopkins, J.D., Westinghouse Hanford

    1996-06-12

    There are 177 radioactive waste storage tanks at the Hanford Site. The waste generates flammable gases. The waste releases gas continuously, but in some tanks the waste has shown a tendency to trap these flammable gases. When enough gas is trapped in a tank`s waste matrix, it may be released in a way that renders part or all of the tank atmosphere flammable for a period of time. Tanks must be evaluated against previously defined criteria to determine whether they can present a flammable gas hazard. This document presents the methodology for evaluating tanks in two areas of concern in the tank headspace:steady-state flammable-gas concentration resulting from continuous release, and concentration resulting from an episodic gas release.

  8. Depleted uranium disposal options evaluation

    SciTech Connect

    Hertzler, T.J.; Nishimoto, D.D.; Otis, M.D.

    1994-05-01

    The Department of Energy (DOE), Office of Environmental Restoration and Waste Management, has chartered a study to evaluate alternative management strategies for depleted uranium (DU) currently stored throughout the DOE complex. Historically, DU has been maintained as a strategic resource because of uses for DU metal and potential uses for further enrichment or for uranium oxide as breeder reactor blanket fuel. This study has focused on evaluating the disposal options for DU if it were considered a waste. This report is in no way declaring these DU reserves a ``waste,`` but is intended to provide baseline data for comparison with other management options for use of DU. To PICS considered in this report include: Retrievable disposal; permanent disposal; health hazards; radiation toxicity and chemical toxicity.

  9. Performance Criteria and Evaluation System

    Energy Science and Technology Software Center

    1992-06-18

    The Performance Criteria and Evaluation System (PCES) was developed in order to make a data base of criteria accessible to radiation safety staff. The criteria included in the package are applicable to occupational radiation safety at DOE reactor and nonreactor nuclear facilities, but any data base of criteria may be created using the Criterion Data Base Utiliity (CDU). PCES assists personnel in carrying out oversight, line, and support activities.

  10. Biological sludge stabilization reactor evaluations

    SciTech Connect

    Corbitt, R.A.; Bowen, P.T.; Smith, P.E.

    1998-07-01

    Anaerobic digestion was chosen as the means to stabilize primary and thickened waste activated sludge for a 0.88 m{sup 3}/s (20 mgd) advanced wastewater reclamation facility. Two stage digestion was proposed to produce Class B sludge. Reactor shape was an important variable in design of the first stage digestion. Evaluation of conventional and egg shaped anaerobic digesters was performed. Based on the economic and non-economic criteria analysis, egg shaped reactors were selected.

  11. LLNL-TR-411568 Evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    568 Evaluation of Simulated Precipitation in CCSM3: Annual Cycle Performance Metrics at Watershed Scales Peter J. Gleckler, David C. Bader March 26, 2009 Disclaimer This document was prepared as an account of work sponsored by an agency of the United States government. Neither the United States government nor Lawrence Livermore National Security, LLC, nor any of their employees makes any warranty, expressed or implied, or assumes any legal liability or responsibility for the accuracy,

  12. Workplace Charging Challenge Partner: Northwest Evaluation Association

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    (NWEA) | Department of Energy Northwest Evaluation Association (NWEA) Workplace Charging Challenge Partner: Northwest Evaluation Association (NWEA) Workplace Charging Challenge Partner: Northwest Evaluation Association (NWEA) Joined the Challenge: July 2015 Headquarters: Portland, OR Charging Location: Portland, OR Domestic Employees: 400 Northwest Evaluation Association (NWEA) encourages and supports many forms of public and personal sustainable transportation modes. Workplace charging is

  13. Section M: Evaluations Factors for Award

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    V SECTION M EVALUATION FACTORS FOR AWARD Request for Proposal # DE-RP36-07GO97036 PART V SECTION M EVALUATION FACTORS FOR AWARD TABLE OF CONTENTS M.1 Evaluation of Proposals ..........................................................................................1 M.2 Evaluation Criteria..................................................................................................1 M.3 Basis For Award

  14. Carbon flows and economic evaluation of mitigation options in Tanzani's forest sector

    SciTech Connect

    Makundi, W.R.; Okinting'Ati, Aku

    1995-02-02

    This paper presents estimates of the rate of forest use, deforestation and forest degradation, as well as the corresponding carbon flows, in the Tanzanian forest sector. It is estimated that the country lost 525,000 ha of forests in 1990, with associated committed emissions of 31.5 Mt. Carbon (MtC), and 7.05 MtC of committed carbon sequestration. The paper then describes the possible response options in the forest sector to mitigate GHG emissions, and evaluates the most stable subset of these-i.e. forest conservation, woodfuel plantations and agroforestry. The conservation options were found to cost an average of U.S. $1.27 per tonne of carbon (tC) conserved. Five options for fuelwood plantations and agroforestry, with two different ownership regimes were evaluated. Each one of the options gives a positive net present value at low rates of discount, ranging from U.S. $1.06 to 3.4/1C of avoided emissions at 0 percent discount rate. At 10 percent discount, the eucalyptus and maize option has a highest PNV of U.S. $1.73 tC, and the government plantation gives a negative PNV (loss) of U.S. $0.13 tC sequestered. The options with a private/community type of ownership scheme fared better than government run options. This conclusion also held true when ranking the options by the BRAC indicator, with the government fuelwood plantation ranked the lowest, and the private agroforestry option of eucalyptus and corn performing best. The mitigation options evaluated here show that the forest sector in Tanzania has one of the most cost-effective GHG mitigation opportunities in the world, and they are within the developmental aspirations of the country.

  15. Independent Oversight Evaluation, Office of Secure Transportation -

    Office of Environmental Management (EM)

    February 2004 | Department of Energy Evaluation, Office of Secure Transportation - February 2004 Independent Oversight Evaluation, Office of Secure Transportation - February 2004 February 2004 Evaluation of the Office of Secure Transportation Emergency Management Program This report provides the results of an independent oversight evaluation of the emergency management program at the Department of Energy's (DOE) Office of Secure Transportation. The evaluation was performed in October 2003 by

  16. Evidence-Based Evaluations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Evidence-Based Evaluations Evidence-Based Evaluations Evidence-based evaluations comprise one of the three pillars of the Office of Technology Transitions (OTT). The office emphasizes how DOE's long-term investments in science and technology have grown into critical technologies that support the economic, energy, environment, and national security missions of the Department. OTT analyzes and evaluates programs and collects metrics for technology transitions across the Department. Evaluation

  17. Enhanced Geothermal Systems (EGS) well construction technology evaluation report.

    SciTech Connect

    Capuano, Louis, Jr.; Huh, Michael; Swanson, Robert; Raymond, David Wayne; Finger, John Travis; Mansure, Arthur James; Polsky, Yarom; Knudsen, Steven Dell

    2008-12-01

    Electricity production from geothermal resources is currently based on the exploitation of hydrothermal reservoirs. Hydrothermal reservoirs possess three ingredients critical to present day commercial extraction of subsurface heat: high temperature, in-situ fluid and high permeability. Relative to the total subsurface heat resource available, hydrothermal resources are geographically and quantitatively limited. A 2006 DOE sponsored study led by MIT entitled 'The Future of Geothermal Energy' estimates the thermal resource underlying the United States at depths between 3 km and 10 km to be on the order of 14 million EJ. For comparison purposes, total U.S. energy consumption in 2005 was 100 EJ. The overwhelming majority of this resource is present in geological formations which lack either in-situ fluid, permeability or both. Economical extraction of the heat in non-hydrothermal situations is termed Enhanced or Engineered Geothermal Systems (EGS). The technologies and processes required for EGS are currently in a developmental stage. Accessing the vast thermal resource between 3 km and 10 km in particular requires a significant extension of current hydrothermal practice, where wells rarely reach 3 km in depth. This report provides an assessment of well construction technology for EGS with two primary objectives: (1) Determining the ability of existing technologies to develop EGS wells. (2) Identifying critical well construction research lines and development technologies that are likely to enhance prospects for EGS viability and improve overall economics. Towards these ends, a methodology is followed in which a case study is developed to systematically and quantitatively evaluate EGS well construction technology needs. A baseline EGS well specification is first formulated. The steps, tasks and tools involved in the construction of this prospective baseline EGS well are then explicitly defined by a geothermal drilling contractor in terms of sequence, time and cost. A

  18. The multifamily building evaluation project

    SciTech Connect

    1995-03-01

    In 1991 the New York State Energy Office embarked on a comprehensive multi-year study of multifamily housing in New York City. The principal objective of the evaluation was to determine the degree to which new windows and boiler/burner retrofits installed in 22 multifamily buildings located in the New York City region save energy and whether the savings persist over a minimum of two years. Window and boiler retrofits were selected because they are popular measures and are frequently implemented with assistance from government and utility energy programs. Approaches prospectively, energy consumption monitoring and a series of on-site inspections helped explain why energy savings exceeded or fell short of expectations. In 1993, the scope of the evaluation expanded to include the monitoring of domestic hot water (DHW) consumption in order to better understand the sizing of combined heating/DHW boilers and water consumption patterns. The evaluation was one of ten proposals selected from over 100 candidates in a nationwide competition for a US Department of Energy Building Efficiency Program Grant. The Energy Office managed the project, analyzed the data and prepared the reports, Lawrence Berkeley Laboratory served as technical advisor, and EME Group (New York City) installed meters and dataloggers, collected data, and inspected the retrofits. The New York State Energy Research and Development Authority collaborated with the Energy Office on the DHW monitoring component. Results did not always follow predictable patterns. Some buildings far exceeded energy saving estimates while others experienced an increase in consumption. Persistence patterns were mixed. Some buildings showed a steady decline in energy savings while others demonstrated a continual improvement. A clear advantage of the research design was a frequent ability to explain results.

  19. Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism

    SciTech Connect

    Incardona, John P. . E-mail: john.incardona@noaa.gov; Day, Heather L.; Collier, Tracy K.; Scholz, Nathaniel L.

    2006-12-15

    Polycyclic aromatic hydrocarbons (PAHs) derived from fossil fuels are ubiquitous contaminants and occur in aquatic habitats as highly variable and complex mixtures of compounds containing 2 to 6 rings. For aquatic species, PAHs are generally accepted as acting through either of two modes of action: (1) 'dioxin-like' toxicity mediated by activation of the aryl hydrocarbon receptor (AHR), which controls a battery of genes involved in PAH metabolism, such as cytochrome P4501A (CYP1A) and (2) 'nonpolar narcosis', in which tissue uptake is dependent solely on hydrophobicity and toxicity is mediated through non-specific partitioning into lipid bilayers. As part of a systematic analysis of mechanisms of PAH developmental toxicity in zebrafish, we show here that three tetracyclic PAHs (pyrene, chrysene, and benz[a]anthracene) activate the AHR pathway tissue-specifically to induce distinct patterns of CYP1A expression. Using morpholino knockdown of ahr1a, ahr2, and cyp1a, we show that distinct embryolarval syndromes induced by exposure to two of these compounds are differentially dependent on tissue-specific activation of AHR isoforms or metabolism by CYP1A. Exposure of embryos with and without circulation (silent heart morphants) resulted in dramatically different patterns of CYP1A induction, with circulation required to deliver some compounds to internal tissues. Therefore, biological effects of PAHs cannot be predicted simply by quantitative measures of AHR activity or a compound's hydrophobicity. These results indicate that current models of PAH toxicity in fish are greatly oversimplified and that individual PAHs are pharmacologically active compounds with distinct and specific cellular targets.

  20. Low functional programming of renal AT{sub 2}R mediates the developmental origin of glomerulosclerosis in adult offspring induced by prenatal caffeine exposure

    SciTech Connect

    Ao, Ying; Sun, Zhaoxia; Hu, Shuangshuang; Zuo, Na; Li, Bin; Yang, Shuailong; Xia, Liping; Wu, Yong; Wang, Linlong; He, Zheng; Wang, Hui

    2015-09-01

    Our previous study has indicated that prenatal caffeine exposure (PCE) could induce intrauterine growth retardation (IUGR) of offspring. Recent research suggested that IUGR is a risk factor for glomerulosclerosis. However, whether PCE could induce glomerulosclerosis and its underlying mechanisms remain unknown. This study aimed to demonstrate the induction to glomerulosclerosis in adult offspring by PCE and its intrauterine programming mechanisms. A rat model of IUGR was established by PCE, male fetuses and adult offspring at the age of postnatal week 24 were euthanized. The results revealed that the adult offspring kidneys in the PCE group exhibited glomerulosclerosis as well as interstitial fibrosis, accompanied by elevated levels of serum creatinine and urine protein. Renal angiotensin II receptor type 2 (AT{sub 2}R) gene expression in adult offspring was reduced by PCE, whereas the renal angiotensin II receptor type 1a (AT{sub 1a}R)/AT{sub 2}R expression ratio was increased. The fetal kidneys in the PCE group displayed an enlarged Bowman's space and a shrunken glomerular tuft, accompanied by a reduced cortex width and an increase in the nephrogenic zone/cortical zone ratio. Observation by electronic microscope revealed structural damage of podocytes; the reduced expression level of podocyte marker genes, nephrin and podocin, was also detected by q-PCR. Moreover, AT{sub 2}R gene and protein expressions in fetal kidneys were inhibited by PCE, associated with the repression of the gene expression of glial-cell-line-derived neurotrophic factor (GDNF)/tyrosine kinase receptor (c-Ret) signaling pathway. These results demonstrated that PCE could induce dysplasia of fetal kidneys as well as glomerulosclerosis of adult offspring, and the low functional programming of renal AT{sub 2}R might mediate the developmental origin of adult glomerulosclerosis. - Highlights: • Prenatal caffeine exposure induces glomerulosclerosis in adult offspring. • Prenatal caffeine

  1. Hygroscopicity Evaluation of Halide Scintillators

    SciTech Connect

    Zhuravleva, M; Stand, L; Wei, H; Hobbs, C. L.; Boatner, Lynn A; Ramey, Joanne Oxendine; Burger, Arnold; Rowe, E; Bhattacharya, P.; Tupitsyn, E; Melcher, Charles L

    2014-01-01

    A collaborative study of relative hygroscopicity of anhydrous halide scintillators grown at various laboratories is presented. We have developed a technique to evaluate moisture sensitivity of both raw materials and grown crystals, in which the moisture absorption rate is measured using a gravimetric analysis. Degradation of the scintillation performance was investigated by recording gamma-ray spectra and monitoring the photopeak position, count rate and energy resolution. The accompanying physical degradation of the samples exposed to ambient atmosphere was photographically recorded as well. The results were compared with ben

  2. Evaluating Storage Systems for Lustre

    SciTech Connect

    Oral, H. Sarp

    2015-08-20

    Storage systems are complex, including multiple subsystems and components. Sustained operations with top performance require all these subsystems and components working as expected. Having a detailed performance profile helps establishing a baseline. This baseline can be used for easier identification of possible future problems. A systematic bottom-to-top approach, starting with a detailed performance analysis of disks and moving up across layers and subsystems, provides a quantitative breakdown of each component's capabilities and bottlenecks. Coupling these low-level tests with Lustre-level evaluations will present a better understanding of performance expectations under different I/O workloads.

  3. Engineering Evaluation/Cost Analysis

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    PPPO/03-0145&D2 Engineering Evaluation/Cost Analysis for Group 1 Buildings X-103, X-334, and X-344B at the Portsmouth Gaseous Diffusion Plant, Piketon, Ohio This document has been approved for public release: Henry H. Thomas (signature on file) 10/29/10 Classification & Information Control Officer Date Restoration Services, Inc. (RSI) contributed to the preparation of this document and should not be considered an eligible contractor for its review DOE/PPPO/03-0145&D2 Engineering

  4. Concurrent ultrasonic weld evaluation system

    DOEpatents

    Hood, D.W.; Johnson, J.A.; Smartt, H.B.

    1987-12-15

    A system for concurrent, non-destructive evaluation of partially completed welds for use in conjunction with an automated welder is disclosed. The system utilizes real time, automated ultrasonic inspection of a welding operation as the welds are being made by providing a transducer which follows a short distance behind the welding head. Reflected ultrasonic signals are analyzed utilizing computer based digital pattern recognition techniques to discriminate between good and flawed welds on a pass by pass basis. The system also distinguishes between types of weld flaws. 5 figs.

  5. Evaluation of Retrofit Delivery Packages

    SciTech Connect

    Berman, M.; Smith, P.; Porse, E.

    2013-07-01

    Residential energy retrofit activities are a critical component of efforts to increase energy efficiency in the U.S. building stock; however, retrofits account for a small percentage of aggregate energy savings at relatively high per unit costs. This report by Building America research team, Alliance for Residential Building Innovation (ARBI), describes barriers to widespread retrofits and evaluates opportunities to improve delivery of home retrofit measures by identifying economies of scale in marketing, energy assessments, and bulk purchasing through pilot programs in portions of Sonoma, Los Angeles, and San Joaquin Counties, CA. These targeted communities show potential and have revealed key strategies for program design, as outlined in the report.

  6. Concurrent ultrasonic weld evaluation system

    DOEpatents

    Hood, D.W.; Johnson, J.A.; Smartt, H.B.

    1985-09-04

    A system for concurrent, non-destructive evaluation of partially completed welds for use in conjunction with an automated welder. The system utilizes real time, automated ultrasonic inspection of a welding operation as the welds are being made by providing a transducer which follows a short distance behind the welding head. Reflected ultrasonic signals are analyzed utilizing computer based digital pattern recognition techniques to discriminate between good and flawed welds on a pass by pass basis. The system also distinguishes between types of weld flaws.

  7. Concurrent ultrasonic weld evaluation system

    DOEpatents

    Hood, Donald W.; Johnson, John A.; Smartt, Herschel B.

    1987-01-01

    A system for concurrent, non-destructive evaluation of partially completed welds for use in conjunction with an automated welder. The system utilizes real time, automated ultrasonic inspection of a welding operation as the welds are being made by providing a transducer which follows a short distance behind the welding head. Reflected ultrasonic signals are analyzed utilizing computer based digital pattern recognition techniques to discriminate between good and flawed welds on a pass by pass basis. The system also distinguishes between types of weld flaws.

  8. Citation of TUNL Evaluated Data

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    How should I cite these pages? It is important to cite information you obtain from this web site, just as you would a journal article or book. Here are a few helpful examples of how to format references and items found on this website. Examples Publications: For publications please cite the journal Nuclear Physics A that the evaluation was published in. For example, ``Energy Levels of Light Nuclei, A = 20'' should be cited as: D.R. Tilley, C.M. Cheves, J.H. Kelley, S. Raman and H.R. Weller,

  9. DWPF MATERIALS EVALUATION SUMMARY REPORT

    SciTech Connect

    Gee, T.; Chandler, G.; Daugherty, W.; Imrich, K.; Jankins, C.

    1996-09-12

    To better ensure the reliability of the Defense Waste Processing Facility (DWPF) remote canyon process equipment, a materials evaluation program was performed as part of the overall startup test program. Specific test programs included FA-04 ('Process Vessels Erosion/Corrosion Studies') and FA-05 (melter inspection). At the conclusion of field testing, Test Results Reports were issued to cover the various test phases. While these reports completed the startup test requirements, DWPF-Engineering agreed to compile a more detailed report which would include essentially all of the materials testing programs performed at DWPF. The scope of the materials evaouation programs included selected equipment from the Salt Process Cell (SPC), Chemical Process Cell (CPC), Melt Cell, Canister Decon Cell (CDC), and supporting facilities. The program consisted of performing pre-service baseline inspections (work completed in 1992) and follow-up inspections after completion of the DWPF cold chemical runs. Process equipment inspected included: process vessels, pumps, agitators, coils, jumpers, and melter top head components. Various NDE (non-destructive examination) techniques were used during the inspection program, including: ultrasonic testing (UT), visual (direct or video probe), radiography, penetrant testing (PT), and dimensional analyses. Finally, coupon racks were placed in selected tanks in 1992 for subsequent removal and corrosion evaluation after chemical runs.

  10. Microdrill Initiative - Initial Market Evaluation

    SciTech Connect

    Spears & Associates, Inc

    2003-07-01

    The U.S. Department of Energy (DOE) is launching a major research and development initiative to create a small, fast, inexpensive and environmentally friendly rig for drilling 5000 feet boreholes to investigate potential oil and gas reservoirs. DOE wishes to get input from petroleum industry operators, service companies and equipment suppliers on the operation and application of this coiled-tubing-based drilling unit. To that end, DOE has asked Spears & Associates, Inc. (SAI) to prepare a special state-of-the-market report and assist during a DOE-sponsored project-scoping workshop in Albuquerque near the end of April 2003. The scope of the project is four-fold: (1) Evaluate the history, status and future of demand for very small bore-hole drilling; (2) Measure the market for coiled tubing drilling and describe the state-of-the-art; (3) Identify companies and individuals who should have an interest in micro drilling and invite them to the DOE workshop; and (4) Participate in 3 concurrent workshop sessions, record and evaluate participant comments and report workshop conclusions.

  11. RL's Fiscal Year 2013 Fee Evaluation Summary

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    September 2013 Basis of Evaluation: Performance Evaluation and Measurement Plan (PEMP) Award Fee Available: 21,030,647 Award Fee Earned: 19,352,402 (92%) Award Fee Area ...

  12. Waste feed delivery test and evaluation plan

    SciTech Connect

    O'TOOLE, S.M.

    1999-09-30

    This plan documents the Waste Feed Delivery Program test and evaluation planning and implementation approach. The purpose of this document is to define and communicate the Waste Feed Delivery Program Test and Evaluation scope, objectives, planning and implementation approach.

  13. Develop & evaluate materials & additives that enhance thermal...

    Energy.gov [DOE] (indexed site)

    Annual Merit Review and Peer Evaluation Meeting, May 18-22, 2009 -- Washington D.C. esp23amine.pdf (1.24 MB) More Documents & Publications Develop and Evaluate Materials and ...

  14. NREL: Transportation Research - Fleet Test and Evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Fleet Test and Evaluation Photo of medium-duty truck with the words plug-in all electric vehicle on its side. NREL evaluates the real-world performance of advanced medium- and ...

  15. Program Evaluation: Checklists, Forms, and Guides

    Energy.gov [DOE]

    This section of the site provides for you in one place and ready to print current EERE evaluation guides, checklists for doing an evaluation, and forms to collect such things as statements of...

  16. Program Evaluation: Define Questions and Methods

    Office of Energy Efficiency and Renewable Energy (EERE)

    Steps five through eight will help you define the questions your evaluation should address, and develop the methods you'll use to conduct your evaluation (learn more about the other steps in...

  17. Evaluation of End Mill Coatings

    SciTech Connect

    L. J. Lazarus; R. L. Hester,

    2005-08-01

    Milling tests were run on families of High Speed Steel (HSS) end mills to determine their lives while machining 304 Stainless Steel. The end mills tested were made from M7, M42 and T15-CPM High Speed Steels. The end mills were also evaluated with no coatings as well as with Titanium Nitride (TiN) and Titanium Carbo-Nitride (TiCN) coatings to determine which combination of HSS and coating provided the highest increase in end mill life while increasing the cost of the tool the least. We found end mill made from M42 gave us the largest increase in tool life with the least increase in cost. The results of this study will be used by Cutting Tool Engineering in determining which end mill descriptions will be dropped from our tool catalog.

  18. Desalination technology evaluation. Final report

    SciTech Connect

    Del Bene, J.V.; Loh, G.T.; Schleicher, R.W.; Sgammato, T.A.; Sinha, A.K.

    1992-12-01

    The shortage of potable water has hindered economic development in South Florida and other areas of the United States. This project, cosponsored with Florida Power & Light (FPL), examines the economics of colocation of a water desalination plant with an electric power plant to take advantage of shared facilities, personnel, and equipments well as existing intake and outfall structures. In combination, these factors should reduce the cost of desalinated water. The first step in determining the viability of colocation is identification of desalination technologies best suited for dual-purpose applications in retrofits at existing fossil plants. Based on energy efficiency and commercial maturity, reverse osmosis (RO) and low-temperature multieffect distillation (LT-MED) technologies appear to be the best candidates for such application. In fact, RO provides the best economics for the plants and conditions studied. Of the emerging technologies evaluated, sodium molecular pumping and solvent extraction technologies should be further investigated for their potential in significantly reducing desalination costs.

  19. Sequentially Executed Model Evaluation Framework

    SciTech Connect

    2014-02-14

    Provides a message passing framework between generic input, model and output drivers, and specifies an API for developing such drivers. Also provides batch and real-time controllers which step the model and 1/0 through the time domain (or other discrete domain), and sample 1/0 drivers. This is a Framework library framework, and does not, itself, solve any problems or execute any modelling. The SeMe framework aids in development of models which operate on sequential information, such as time-series, where evaluation is based on prior results combined with new data for this iteration. Ha) applications in quality monitoring, and was developed as part of the CANARY-EDS software, where real-time water quality data is being analyzed

  20. Sequentially Executed Model Evaluation Framework

    Energy Science and Technology Software Center

    2014-02-14

    Provides a message passing framework between generic input, model and output drivers, and specifies an API for developing such drivers. Also provides batch and real-time controllers which step the model and 1/0 through the time domain (or other discrete domain), and sample 1/0 drivers. This is a Framework library framework, and does not, itself, solve any problems or execute any modelling. The SeMe framework aids in development of models which operate on sequential information, suchmore » as time-series, where evaluation is based on prior results combined with new data for this iteration. Ha) applications in quality monitoring, and was developed as part of the CANARY-EDS software, where real-time water quality data is being analyzed« less

  1. Sequentially Executed Model Evaluation Framework

    Energy Science and Technology Software Center

    2015-10-20

    Provides a message passing framework between generic input, model and output drivers, and specifies an API for developing such drivers. Also provides batch and real-time controllers which step the model and I/O through the time domain (or other discrete domain), and sample I/O drivers. This is a library framework, and does not, itself, solve any problems or execute any modeling. The SeMe framework aids in development of models which operate on sequential information, such asmore » time-series, where evaluation is based on prior results combined with new data for this iteration. Has applications in quality monitoring, and was developed as part of the CANARY-EDS software, where real-time water quality data is being analyzed for anomalies.« less

  2. Field Evaluation of Programmable Thermostats

    SciTech Connect

    Sachs, O.; Tiefenbeck, V.; Duvier, C.; Qin, A.; Cheney, K.; Akers, C.; Roth, K.

    2012-12-01

    Prior research suggests that poor programmable thermostats usability may prevent their effective use to save energy. We hypothesized that home occupants with a high-usability thermostats would be more likely to use them to save energy than people with a basic thermostat. We randomly installed a high-usability thermostat in half the 77 apartments of an affordable housing complex, installing a basic thermostat in the other half. During the heating season, we collected space temperature and furnace on-off data to evaluate occupant interaction with the thermostats, foremost nighttime setbacks. We found that thermostat usability did not influence energy-saving behaviors, finding no significant difference in temperature maintained among apartments with high- and low-usability thermostats.

  3. Evaluation of recent residential inverters

    SciTech Connect

    Nichols, B.E.

    1982-06-01

    Seven residential utility-interactive inverters for photovoltaic power systems have been evaluated at MIT Laboratory and at the Northeast Residential Experiment Station (NE RES). Two, a Windworks Gemini and an Abacus Sunverter, have been reported on previously. Reviewed here are five other inverters: Windworks Gemini 8-kW (dc) model with an ac filter to improve the output current waveform and power factor; Acheval Wind Electronics 10-kW (ac) model, Helionetics 6-kW (dc) model; and American Power Conversion 2-kW and 4-kW (ac) models. Input and output power, power factor, current waveform distortion, audio noise and radio frequency interference measurements were made at the NE RES and the results are presented.

  4. SYNTHETIC SLING FAILURE - EVALUATIONS & RECOMMENDATIONS

    SciTech Connect

    MACKEY TC; HENDERSON CS

    2009-10-26

    The information and evaluations provided in this report were compiled to address the recurring problem of synthetic sling failure. As safety is the number one priority in all work aspects, a solution must be devised to prevent accidents from occurring. A total of thirteen cases regarding synthetic sling failure were evaluated in order to determine their causes, effects, and preventative measures. From the collected data, it was found that all cases in which the synthetic sling contacted the edge of its load resulted in sling failure. It is required that adequate synthetic sling protection devices be used to protect slings in any lift where the sling comes in direct contact with the edge or corner of its load. However, there are no consensus codes or standards stating the type, material, or purpose of the type of protective device used to protect the sling from being cut. Numerous industry standards and codes provide vague descriptions on how to protect synthetic slings. Without a clear, concise statement of how to protect synthetic slings, it is common for inadequate materials and sling protection devices to be used in an attempt to meet the intent of these requirements. The use of an inadequate sling protection device is the main cause of synthetic sling failure in all researched cases. Commercial sling protection devices come in many shapes and sizes, and have a variety of names, as well as advertised uses. 'Abrasion pads' and 'wear protectors' are two different names for products with the same intended purpose. There is no distinguishable way to determine the extent of sling protection which these devices will provide, or what specific scenarios they are made for. This creates room for error in a field where error is unacceptable. This report provides a recommended action for hoisting and rigging activities which require synthetic slings to contact a load, as well as recommended changes to industry standards which will benefit overall industry safety.

  5. ENergy and Power Evaluation Program

    SciTech Connect

    1996-11-01

    In the late 1970s, national and international attention began to focus on energy issues. Efforts were initiated to design and test analytical tools that could be used to assist energy planners in evaluating energy systems, particularly in developing countries. In 1984, the United States Department of Energy (DOE) commissioned Argonne National Laboratory`s Decision and Information Sciences Division (DIS) to incorporate a set of analytical tools into a personal computer-based package for distribution in developing countries. The package developed by DIS staff, the ENergy and Power Evaluation Program (ENPEP), covers the range of issues that energy planners must face: economic development, energy demand projections, supply-and-demand balancing, energy system expansion, and environmental impact analysis. Following the original DOE-supported development effort, the International Atomic Energy Agency (IAEA), with the assistance from the US Department of State (DOS) and the US Department of Energy (DOE), provided ENPEP training, distribution, and technical support to many countries. ENPEP is now in use in over 60 countries and is an international standard for energy planning tools. More than 500 energy experts have been trained in the use of the entire ENPEP package or some of its modules during the international training courses organized by the IAEA in collaboration with Argonne`s Decision and Information Sciences (DIS) Division and the Division of Educational Programs (DEP). This report contains the ENPEP program which can be download from the internet. Described in this report is the description of ENPEP Program, news, forums, online support and contacts.

  6. Design and Evaluation of High Capacity Cathodes

    Energy.gov [DOE]

    2013 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting

  7. Service Center Evaluation Guide | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Service Center Evaluation Guide Service Center Evaluation Guide To be assured of a quality product, customers of motor repair service centers need to be knowledgeable about the service they're purchasing. This guide provides information to assist in evaluating motor repair service centers. Service Center Evaluation Guide (November 1999) (1.27 MB) More Documents & Publications Selected Bibliography on Electric Motor Repair Motor Repair Tech Brief Model Repair Specifications for Low Voltage

  8. Program Evaluation: Related Links | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    University Evaluation Resource Centers Institute for Social Research, University of Michigan International Institute for Qualitative Methodology, University of Alberta National ...

  9. SEP National Evaluation Update for STEAB

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    SEP National Evaluation Update for STEAB Martin Schweitzer Oak Ridge National Laboratory March 13, 2013 2 Managed by UT-Battelle for the Department of Energy NC Weatherization Evaluation Briefing Introduction  State Energy Program (SEP) National Evaluation is well underway  This study will quantify key program outcomes for program year 2008 and ARRA period  Study is being performed by independent evaluation team (DNV KEMA and subcontractors) and managed by ORNL  Final report expected

  10. Evaluation and Characterization of Lightweight Materials: Success...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Characterization of Lightweight Materials: Success Stories from the High Temperature Materials Laboratory (HTML) User Program Evaluation and Characterization of Lightweight...

  11. Fuel Cell Electric Vehicle (FCEV) Evaluation

    SciTech Connect

    Kurtz, Jennifer; Sprik, Sam; Ainscough, Chris; Saur, Genevieve

    2015-12-15

    Overview of NREL's fuel cell electric vehicle (FCEV) evaluation activities presented to the Interagency Working Group on December 15, 2015.

  12. ORNL Weatherization Program Evaluation | Open Energy Information

    OpenEI (Open Energy Information) [EERE & EIA]

    Program Evaluation AgencyCompany Organization: Oak Ridge National Laboratory Sector: Energy Focus Area: Buildings Topics: Policiesdeployment programs Website:...

  13. ORNL Weatherization Program Evaluation | Open Energy Information

    OpenEI (Open Energy Information) [EERE & EIA]

    Weatherization Program Evaluation AgencyCompany Organization: Oak Ridge National Laboratory Sector: Energy Focus Area: Buildings Topics: Policiesdeployment programs Website:...

  14. Hazard Evaluation for 244-CR Vault

    SciTech Connect

    GRAMS, W.H.

    1999-08-19

    This document presents the results of a hazards identification and evaluation performed on the 244-CR Vault to close a USQ (USQ No.TF-98-0785, Potential Inadequacy in Authorization Basis (PIAB): To Evaluate Miscellaneous Facilities Listed In HNF-2503 And Not Addressed In The TWRS Authorization Basis) that was generated as part of an evaluation of inactive TWRS facilities.

  15. Hysterosalpingography using a flat panel unit: Evaluation and optimization of ovarian radiation dose

    SciTech Connect

    Messaris, Gerasimos A. T.; Abatzis, Ilias; Kagadis, George C.; Samartzis, Alexandros P.; Athanasopoulou, Panagiota; Christeas, Nikolaos; Katsanos, Konstantinos; Karnabatidis, Dimitrios; Nikiforidis, George C.

    2012-07-15

    Purpose: The aim of the present study was the evaluation and optimization of radiation dose to the ovaries (D) in hysterosalpingography (HSG). Methods: The study included a phantom study and a clinical one. In the phantom study, we evaluated imaging results for different geometrical setups and irradiation conditions. In the clinical study, 34 women were assigned into three different fluoroscopy modes and D was estimated with direct cervical TLD measurements. Results: In the phantom study, we used a source-to-image-distance (SID) of 110 cm and a field diagonal of 48 cm, and thus decreased air KERMA rate (KR) by 19% and 70%, respectively, for beam filtration: 4 mm Al and 0.9 mm Cu (Low dose). The least radiation exposure was accomplished by using the 3.75 pps fluoroscopy mode in conjunction with beam filtration: Low dose. In the clinical study, D normalized to 50 s of fluoroscopy time with a 3.75 pps fluoroscopy mode reached a value of 0.45 {+-} 0.04 mGy. Observers' evaluation of diagnostic image quality did not significantly differ for the three different modes of acquisition that were compared. Conclusions: Digital spot radiographs could be omitted in modern flat panel systems during HSG. Fluoroscopy image acquisitions in a modern flat panel unit at 3.75 pps and a beam filtration of 4 mm Al and 0.9 mm Cu demonstrate acceptable image quality with an average D equal to 0.45 mGy. This value is lower compared to the studied literature. For these reasons, the proposed method may be recommended for routine HSG examination in order to limit radiation exposure to the ovaries.

  16. EERE Guide for Managing General Program Evaluation Studies

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    ... 34 Table 6. Selection of Evaluation Research Design for Impact Evaluations... 35 Table 7. Example:...

  17. SOP for General Program Evaluations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    General Program Evaluations SOP for General Program Evaluations SOP for General Program Evaluations: Quality Assurance for General Program Evaluation Studies, June 26, 2006. SOP for General Program Evaluations (1.48 MB) More Documents & Publications General Evaluation SOP 6-26 2006 PAE Evaluation Portfolio Peer Review PAE Evaluation Portfolio Peer Review

  18. Porous media experience applicable to field evaluation for compressed air energy storage

    SciTech Connect

    Allen, R.D.; Gutknecht, P.J.

    1980-06-01

    A survey is presented of porous media field experience that may aid in the development of a compressed air energy storage field demonstration. Work done at PNL and experience of other groups and related industries is reviewed. An overall view of porous media experience in the underground storage of fluids is presented. CAES experience consists of site evaluation and selection processes used by groups in California, Kansas, and Indiana. Reservoir design and field evaluation of example sites are reported. The studies raised questions about compatibility with depleted oil and gas reservoirs, storage space rights, and compressed air regulations. Related experience embraces technologies of natural gas, thermal energy, and geothermal and hydrogen storage. Natural gas storage technology lends the most toward compressed air storage development, keeping in mind the respective differences between stored fluids, physical conditions, and cycling frequencies. Both fluids are injected under pressure into an aquifer to form a storage bubble confined between a suitable caprock structure and partially displaced ground water. State-of-the-art information is summarized as the necessary foundation material for field planning. Preliminary design criteria are given as recommendations for basic reservoir characteristics. These include geometric dimensions and storage matrix properties such as permeability. Suggested ranges are given for injection air temperature and reservoir pressure. The second step in developmental research is numerical modeling. Results have aided preliminary design by analyzing injection effects upon reservoir pressure, temperature and humidity profiles. Results are reported from laboratory experiments on candidate sandstones and caprocks. Conclusions are drawn, but further verification must be done in the field.

  19. CRADA NFE-08-01456 Evaluation of Alumina-Forming Austenitic Stainless Steel Alloys in Industrial Gas Turbines

    SciTech Connect

    Brady, Michael P; Pint, Bruce A; Unocic, Kinga A; Yamamoto, Yukinori; Kumar, Deepak; Lipschutz, Mark D.

    2011-09-01

    Oak Ridge National Laboratory (ORNL) and Solar Turbines Incorporated (Solar) participated in an in-kind cost share cooperative research and development agreement (CRADA) effort under the auspices of the Energy Efficiency and Renewable Energy (EERE) Technology Maturation Program to explore the feasibility for use of developmental ORNL alumina-forming austenitic (AFA) stainless steels as a material of construction for industrial gas turbine recuperator components. ORNL manufactured lab scale foil of three different AFA alloy compositions and delivered them to Solar for creep properties evaluation. One AFA composition was selected for a commercial trial foil batch. Both lab scale and the commercial trial scale foils were evaluated for oxidation and creep behavior. The AFA foil exhibited a promising combination of properties and is of interest for future scale up activities for turbine recuperators. Some issues were identified in the processing parameters used for the first trial commercial batch. This understanding will be used to guide process optimization of future AFA foil material production.

  20. Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis

    SciTech Connect

    Strakovsky, Rita S.; Wang, Huan; Engeseth, Nicki J.; Flaws, Jodi A.; Helferich, William G.; Pan, Yuan-Xiang; Lezmi, Stéphane

    2015-04-15

    Developmental bisphenol A (BPA) exposure increases adulthood hepatic steatosis with reduced mitochondrial function. To investigate the potential epigenetic mechanisms behind developmental BPA-induced hepatic steatosis, pregnant Sprague–Dawley rats were dosed with vehicle (oil) or BPA (100 μg/kg/day) from gestational day 6 until postnatal day (PND) 21. After weaning, offspring were either challenged with a high-fat (HF; 45% fat) or remained on a control (C) diet until PND110. From PND60 to 90, both BPA and HF diet increased the fat/lean ratio in males only, and the combination of BPA and HF diet appeared to cause the highest ratio. On PND110, Oil-HF, BPA-C, and BPA-HF males had higher hepatic lipid accumulation than Oil-C, with microvesicular steatosis being marked in the BPA-HF group. Furthermore, on PND1, BPA increased and modified hepatic triglyceride (TG) and free fatty acid (FFA) compositions in males only. In PND1 males, BPA increased hepatic expression of FFA uptake gene Fat/Cd36, and decreased the expression of TG synthesis- and β-oxidation-related genes (Dgat, Agpat6, Cebpα, Cebpβ, Pck1, Acox1, Cpt1a, Cybb). BPA altered DNA methylation and histone marks (H3Ac, H4Ac, H3Me2K4, H3Me3K36), and decreased the binding of several transcription factors (Pol II, C/EBPβ, SREBP1) within the male Cpt1a gene, the key β-oxidation enzyme. In PND1 females, BPA only increased the expression of genes involved in FFA uptake and TG synthesis (Lpl, Fasn, and Dgat). These data suggest that developmental BPA exposure alters and reprograms hepatic β-oxidation capacity in males, potentially through the epigenetic regulation of genes, and further alters the response to a HF diet. - Highlights: • Developmental BPA exposure exacerbates HF-diet induced steatosis in adult males. • Gestational BPA exposure increases hepatic lipid accumulation in neonatal males. • BPA decreases Cpt1a and other hepatic β-oxidation genes in neonatal males. • BPA alters neonatal male Cpt1a

  1. PCS Security Technology Evaluation Tool

    Energy Science and Technology Software Center

    2007-01-30

    P-STET assists in the security technology decision making process from a costlbeneflt perspective. It aids in addressing such questions as whether to acquire and deploy new security technology, to re-configure an existing product or system, or to maintain status quo. P-STET offers both a qualitative and quantitative option. P-STET is most efficient when tailored to an organization’s security cost/benefit environment. It then serves as both a guide to show what types of security questions shouldmore » be addressed and as a means to analyze the data gathered from the questions to make an informed decision. The quantitative option provides a straightforward way to express costs/benefits in terms of dollars. It relies on the organization to quantify benefits or cost avoidances, and, therefore, best serves as a guide to ensure various cost and benefit angles are evaluated. The qualitative option allows the organization to assess costs by levels with respect to security and PCS budgets, operational impacts, and opportunity costs. Benefits are represented in terms of improvements to the organization’s operations and are also assessed by levels with respect to some benchmark such as compliance with best practices. Results are displayed graphically using radar charts, allowing the user to make a more intuitive decision. The shaded area of each chart represents the overall cost and benefit of the security investment. A good investment is denoted when the ratio of benefit shaded area to cost shaded area is large.« less

  2. Eighteen-Month Final Evaluation of UPS Second Generation Diesel Hybrid-Electric Delivery Vans

    SciTech Connect

    Lammert, M.; Walkowicz, K.

    2012-09-01

    A parallel hybrid-electric diesel delivery van propulsion system was evaluated at a UPS facility in Minneapolis using on-vehicle data logging, fueling, and maintenance records. Route and drive cycle analysis showed different duty cycles for hybrid vs. conventional delivery vans; routes were switched between the study groups to provide a valid comparison. The hybrids demonstrated greater advantage on the more urban routes; the initial conventional vans' routes had less dense delivery zones. The fuel economy of the hybrids on the original conventional group?s routes was 10.4 mpg vs. 9.2 mpg for the conventional group on those routes a year earlier. The hybrid group's fuel economy on the original hybrid route assignments was 9.4 mpg vs. 7.9 mpg for the conventional group on those routes a year later. There was no statistically significant difference in total maintenance cost per mile or for the vehicle total cost of operation per mile. Propulsion-related maintenance cost per mile was 77% higher for the hybrids, but only 52% more on a cost-per-delivery-day basis. Laboratory dynamometer testing demonstrated 13%-36% hybrid fuel economy improvement, depending on duty cycle, and up to a 45% improvement in ton-mi/gal. NOx emissions increased 21%-49% for the hybrids in laboratory testing.

  3. ARM - Spring 2002 Post-Workshop Evaluations

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Post-Workshop Evaluations Outreach Home Room News Publications Traditional Knowledge Kiosks Barrow, Alaska Tropical Western Pacific Site Tours Contacts Students Study Hall About ARM Global Warming FAQ Just for Fun Meet our Friends Cool Sites Teachers Teachers' Toolbox Lesson Plans Spring 2002 Post-Workshop Evaluations This is the analysis of the post-workshop evaluations that were given to teachers in Manus after the ARM Climate Change Teacher Workshops held in spring of 2002. The Manus Workshop

  4. ARM - Spring 2002 Pre-Workshop Evaluations

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Pre-Workshop Evaluations Outreach Home Room News Publications Traditional Knowledge Kiosks Barrow, Alaska Tropical Western Pacific Site Tours Contacts Students Study Hall About ARM Global Warming FAQ Just for Fun Meet our Friends Cool Sites Teachers Teachers' Toolbox Lesson Plans Spring 2002 Pre-Workshop Evaluations This is the analysis of the post-workshop evaluations that were given to teachers in Manus after the ARM Climate Change Teacher Workshops held in spring of 2002. The Manus Workshop

  5. Quantitative damage evaluation of localized deep pitting

    SciTech Connect

    Al Beed, A.A.; Al Garni, M.A.

    2000-04-01

    Localized deep pitting is considered difficult to precisely measure and evaluate using simple techniques and daily-use analysis approaches. A case study was made of carbon steel heat exchangers in a typical fresh cooling water environment that experienced severe pitting. To effectively and precisely evaluate the encountered pitting damage, a simple measurement and analyses approach was devised. In this article, the pitting measurement technique and the damage evaluation approach are presented and discussed in detail.

  6. Hyperion 5113/GP Infrasound Sensor Evaluation.

    SciTech Connect

    Merchant, Bion J.

    2015-08-01

    Sandia National Laboratories has tested and evaluated an infrasound sensor, the 5113/GP manufactured by Hyperion. These infrasound sensors measure pressure output by a methodology developed by the University of Mississippi. The purpose of the infrasound sensor evaluation was to determine a measured sensitivity, transfer function, power, self-noise, dynamic range, and seismic sensitivity. These sensors are being evaluated prior to deployment by the U.S. Air Force.

  7. Program Evaluation: Program Logic | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Program Logic Program Evaluation: Program Logic Step four will help you develop a logical model for your program (learn more about the other steps in general program evaluations): What is a Logic Model? Benefits of Using Logic Modeling Pitfalls and How to Avoid Them Steps to Developing a Logic Model What is a Logic Model? Logic modeling is a thought process program evaluators have found to be useful for at least forty years and has become increasingly popular with program managers during the

  8. Hazard evaluation for 244-AR vault facility

    SciTech Connect

    BRAUN, D.J.

    1999-08-25

    This document presents the results of a hazard identification and evaluation performed on the 244-AR Vault Facility to close a USQ (USQ No.TF-98-0785, Potential Inadequacy in Authorization Basis (PIAB): To Evaluate Miscellaneous Facilities Listed In HNF-2503 And Not Addressed In The TWRS Authorization Basis) that was generated as part of an evaluation of inactive TWRS facilities. A hazard evaluation for the Hanford Site 244-AR Vault Facility was performed. The process and results of the hazard evaluation are provided in this document. A previous hazard evaluation was performed for the 244-AR Vault Facility in 1996 in support of the Basis for Interim Operation (BIO) (HNF-SD-WM-BIO-001, 1998, Revision 1) of the Tank Waste Remediation System (TWRS). The results of that evaluation are provided in the BIO. Upon review of those results it was determined that hazardous conditions that could lead to the release of radiological and toxicological material from the 244-AR vaults due to flooding was not addressed in the original hazards evaluation. This supplemental hazard evaluation addresses this oversight of the original hazard evaluation. The results of the hazard evaluation were compared to the current TWRS BIO to identify any hazardous conditions where Authorization Basis (AB) controls may not be sufficient or may not exist. This document is not part of the AB and is not a vehicle for requesting changes to the AB. It is only intended to provide information about hazardous conditions associated with the condition and configuration of the 244-AR vault facility. The AB Control Decision process could be used to determine the applicability and adequacy of existing AB controls as well as any new controls that may be needed for the identified hazardous conditions associated with 244-AR vault flooding. This hazard evaluation does not constitute an accident analysis.

  9. State Energy Program Recovery Act Evaluation

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    of a major national evaluation of the State Energy Program (SEP), under the Office of Energy Efficiency and Renewable Energy. The National Evaluation of SEP during the American Recovery and Reinvestment Act (ARRA) provides insight into the unique program that was administered by DOE in the national effort to create jobs and promote economic recovery. The National Evaluation was a multiyear, peer-reviewed, statistically robust effort led by Oak Ridge National Laboratory. The purpose of the

  10. Maquoketa Shale Caprock Integrity Evaluation

    SciTech Connect

    Leetaru, Hannes

    2014-09-30

    The Knox Project objective is to evaluate the potential of formations within the Cambrian-Ordovician strata above the Mt. Simon Sandstone (St. Peter Sandstone and Potosi Dolomite) as potential targets for carbon dioxide (CO2) sequestration in the Illinois and Michigan Basins. The suitability of the St. Peter Sandstone and Potosi Dolomite to serve as reservoirs for CO2 sequestration is discussed in separate reports. In this report the data gathered from the Knox project, the Illinois Basin – Decatur Project (IBDP) and Illinois Industrial Carbon Capture and Sequestration project (IL-ICCS) are used to make some conclusions about the suitability of the Maquoketa shale as a confining layer for CO2 sequestration. These conclusions are then upscaled to basin-wide inferences based on regional knowledge. Data and interpretations (stratigraphic, petrophysical, fractures, geochemical, risk, seismic) applicable to the Maquoketa Shale from the above mentioned projects was inventoried and summarized. Based on the analysis of these data and interpretations, the Maquoketa Shale is considered to be an effective caprock for a CO2 injection project in either the Potosi Dolomite or St. Peter Sandstone because it has a suitable thickness (~200ft. ~61m), advantageous petrophysical properties (low effective porosity and low permeability), favorable geomechanical properties, an absence of observable fractures and is regionally extensive. Because it is unlikely that CO2 would migrate upward through the Maquoketa Shale, CO2, impact to above lying fresh water aquifers is unlikely. Furthermore, the observations indicate that CO2 injected into the St. Peter Sandstone or Potosi Dolomite may never even migrate up into the Maquoketa Shale at a high enough concentrations or pressure to threaten the integrity of the caprock. Site specific conclusions were reached by unifying the data and conclusions from the IBDP, ICCS and the Knox projects. In the Illinois Basin, as one looks further away from

  11. Preliminary Energy Savings Impact Evaluation: Better Buildings...

    Energy Saver

    Technical Report (2.51 MB) More Documents & Publications Savings and Economic Impacts of the Better Buildings Neighborhood Program, Final Evaluation Volume 2 Preliminary Energy ...

  12. High Impact Technology Hub Resources for Evaluators

    Energy.gov [DOE]

    The HIT Catalyst conducts technology demonstrations in three main phases: Site Evaluation, Selection and Project Kick-Off, Measurement and Verification Scoping and Plan Development. The following...

  13. Advanced Vehicle Technology Analysis & Evaluation Team

    Energy.gov [DOE]

    Presentation on Advanced Vehicle Technology Analysis & Evaluation Team to the DOE Systems Analysis Workshop held in Washington, D.C. July 28-29, 2004.

  14. Issues evaluation process at Rocky Flats Plant

    SciTech Connect

    Smith, L.C.

    1992-04-16

    This report describes the issues evaluation process for Rocky Flats Plant as established in July 1990. The issues evaluation process was initiated February 27, 1990 with a Charter and Process Overview for short-term implementation. The purpose of the process was to determine the projects required for completion before the Phased Resumption of Plutonium Operations. To determine which projects were required, the issues evaluation process and emphasized risk mitigation, based on a ranking system. The purpose of this report is to document the early design of the issues evaluation process to record the methodologies used that continue as the basis for the ongoing Issues Management Program at Rocky Flats Plant.

  15. EPA Webinar - Travel Efficiency Assessment Method: Evaluating...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    EPA Webinar - Travel Efficiency Assessment Method: Evaluating the Potential to Reduce Emissions in Three Case Study Areas EPA Webinar - Travel Efficiency Assessment Method: ...

  16. Evaluation Report: IG-0620 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Report: IG-0620 Evaluation Report: IG-0620 September 16, 2003 The Department's ... work is needed to correct problems with risk-based security management, continuity of ...

  17. Evaluation Report: IG-0700 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    0 Evaluation Report: IG-0700 September 27, 2005 The Department's Unclassified Cyber Security Program-2005 We found that the Department of Energy (Department) continued to take ...

  18. Evaluation Report: IG-0776 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    76 Evaluation Report: IG-0776 September 18, 2007 The Department's Unclassified Cyber Security Program - 2007 The Department of Energy expects to spend about 300 million in Fiscal ...

  19. Evaluation of Routine Atmospheric Sounding Measurements using...

    Office of Scientific and Technical Information (OSTI)

    Science Plan Citation Details In-Document Search Title: Evaluation of Routine Atmospheric Sounding Measurements using Unmanned Systems (ERASMUS) Science Plan The use of ...

  20. Cross Section Evaluations for Arsenic Isotopes

    SciTech Connect

    Pruet, J; McNabb, D P; Ormand, W E

    2005-03-10

    The authors present an evaluation of cross sections describing reactions with neutrons incident on the arsenic isotopes with mass numbers 75 and 74. Particular attention is paid to (n,2n) reactions. The evaluation for {sup 75}As, the only stable As isotope, is guided largely by experimental data. Evaluation for {sup 74}As is made through calculations with the EMPIRE statistical-model reaction code. Cross sections describing the production and destruction of the 26.8 ns isomer in {sup 74}As are explicitly considered. Uncertainties and covariances in some evaluated cross sections are also estimated.

  1. National Uranium Resource Evaluation: Millett Quadrangle, Nevada

    SciTech Connect

    Mitchell, T.P.; Quade, J.G.

    1982-09-01

    The Millett 1/sup 0/ x 2/sup 0/ National Topographic Map Series quadrangle in central Nevada was evaluated in accordance with criteria developed for the National Uranium Resource Evaluation program to determine areas favorable for uranium deposits. New and previously published radiometric, geochemical, and geologic data were used in the evaluation. Favorable allogenic environments were identified at the margins of granitic intrusions that have discordant contact zones. Eleven areas were studied in detail; of these, eight were determined to be unfavorable, and three lacked sufficient data to be evaluated.

  2. STATISTICAL PERFORMANCE EVALUATION OF SPRING OPERATED PRESSURE...

    Office of Scientific and Technical Information (OSTI)

    VALVE RELIABILITY IMPROVEMENTS 2004 TO 2014 Citation Details In-Document Search Title: STATISTICAL PERFORMANCE EVALUATION OF SPRING OPERATED PRESSURE RELIEF VALVE RELIABILITY ...

  3. Numerical evaluation of effective unsaturated hydraulic properties...

    Office of Scientific and Technical Information (OSTI)

    unsaturated hydraulic properties for fractured rocks Citation Details In-Document Search Title: Numerical evaluation of effective unsaturated hydraulic properties for ...

  4. Performance Evaluation and Analysis Consortium End Station |...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    1 Research Domain: Computer Science The PEAC End Station provides the performance evaluation and performance tool developer communities access to the Leadership Computing Facility ...

  5. Performance Evaluations | National Nuclear Security Administration

    National Nuclear Security Administration (NNSA)

    Performance Evaluations Kansas City National Security Campus (formerly Kansas City Plant) Lawrence Livermore National Laboratory Los Alamos National Laboratory Nevada National ...

  6. Risk Evaluation and Reduction | Department of Energy

    Energy.gov [DOE] (indexed site)

    activities. In addition, the team develops policies and procedures to guide the management and execution of follow-up activities. The team also monitors and evaluates...

  7. Evaluation Report: IG-0569 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    IG-0569 September 13, 2002 The Federal Energy Regulatory Commission's Unclassified Cyber Security Program Evaluation Report on "The Federal Energy Regulatory Commission's...

  8. Evaluation Report: IG-0738 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    IG-0738 Evaluation Report: IG-0738 September 18, 2006 The Department's Unclassified Cyber Security Program-2006 To help accomplish its strategic goals in the areas of...

  9. Program Evaluation Topics and Questions Library

    Energy.gov [DOE]

    Menu of initial questions for a program administrator to use in developing a real-time evaluation survey to collect qualitative data from program contractors.

  10. Geothermal resistivity resource evaluation survey Waunita Hot...

    OpenEI (Open Energy Information) [EERE & EIA]

    resistivity resource evaluation survey Waunita Hot Springs project, Gunnison County, Colorado Jump to: navigation, search OpenEI Reference LibraryAdd to library Report: Geothermal...

  11. Preliminary Energy Savings Impact Evaluation: Better Buildings...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Report Preliminary Energy Savings Impact Evaluation: Better Buildings Neighborhood Program American Recovery and Reinvestment Act of 2009 November 4, 2013 Prepared For: U.S....

  12. Advanced vehicle technology analysis and evaluation activities

    SciTech Connect

    None, None

    2009-01-18

    FY 2007 annual progress report evaluating the technologies and performance characteristics of advanced automotive powertrain components and subsystems in an integrated vehicle systems context.

  13. WPCF Underground Injection Control Disposal Permit Evaluation...

    OpenEI (Open Energy Information) [EERE & EIA]

    WPCF Underground Injection Control Disposal Permit Evaluation and Fact Sheet Jump to: navigation, search OpenEI Reference LibraryAdd to library Report: WPCF Underground Injection...

  14. Micro Kernel Benchmark for Evaluating Computer Performance

    Energy Science and Technology Software Center

    2007-04-06

    Crystal_mk is a micro benchmark that LLNL will use to evaluate vendor's software(e.g. compiler) and hardware(e.g. processor speed, memory design).

  15. Nevada Guidelines for Evaluating and Documenting Traditional...

    OpenEI (Open Energy Information) [EERE & EIA]

    Properties Webpage Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Nevada Guidelines for Evaluating and Documenting Traditional Cultural Properties...

  16. Technologies for Evaluating Fish Passage Through Turbines

    Energy.gov [DOE]

    This report evaluated the feasibility of two types of technologies to observe fish and near neutrally buoyant drogues as they move through hydropower turbines.

  17. ARM - Evaluation Product - Cloud Classification VAP

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    properties includes cloud boundaries, thickness, phase, type, and precipitation information, and hence provides a useful tool for evaluation of model simulations and...

  18. Training Evaluation Administration | Department of Energy

    Energy.gov [DOE] (indexed site)

    of our training solutions. This effort is to ensure that DOE is in compliance with 2009 OPM regulations, which require that agencies evaluate their training programs ...

  19. Energy Efficiency Program Impact Evaluation Guide

    SciTech Connect

    Evaluation, Measurement, and Verification Working Group

    2012-12-20

    The key efficiency evaluation, measurement, and verification resource for novices and experts. Includes definitions, concepts, and steps for calculating savings, avoided emissions, and other impacts.

  20. Chapter 21: Residential Lighting Evaluation Protocol. Uniform...

    Office of Environmental Management (EM)

    Lighting Evaluation Protocol The Uniform Methods Project: Methods for Determining Energy Efficiency Savings for Specific Measures Created as part of subcontract with period of ...

  1. Clothes Dryer Automatic Termination Sensor Evaluation

    SciTech Connect

    TeGrotenhuis, Ward E.

    2014-10-01

    Volume 1: Characterization of Energy Use in Residential Clothes Dryers. The efficacy and energy efficiency of clothes dryers are studied in this evaluation.

  2. Heavy-Duty Vehicle Field Evaluations

    Energy.gov [DOE]

    2009 DOE Hydrogen Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting, May 18-22, 2009 -- Washington D.C.

  3. Evaluating Model Parameterizations of Arctic Processes

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Evaluating Color Rendition Using IES TM-30-15 Evaluating Color Rendition Using IES TM-30-15 A technology fact sheet that provides background information and details about TM-30-15, a new method for evaluating light source color rendition. tm-30_fact-sheet.pdf (3.44 MB) More Documents & Publications presentation slides: UNDERSTANDING AND APPLYING TM-30-15 IES TM-30 Offers Comprehensive System for Evaluating Color Rendition of Light Sources WEBINAR: A TECHNICAL DISCUSSION OF TM-30-15

    Model

  4. Preliminary Energy Savings Impact Evaluation: Better Buildings...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    4, 2013. PDF icon Preliminary Energy Savings Impact Evaluation More Documents & Publications Savings and Economic Impacts of the Better Buildings Neighborhood Program, Final ...

  5. Economic Evaluation of Renewable Energy Projects

    Office of Environmental Management (EM)

    Evaluation of Renewable Energy Projects Sean Skaling, Deputy Director, Alternative Energy and Energy Efficiency DOE Indian Energy Conference, Anchorage, Alaska April 30, 2014 REF ...

  6. Operating Experience Level 3, Nitrate Waste Evaluations

    Energy.gov [DOE]

    OE-3 2016-05: This Operating Experience Level 3 (OE-3) document provides information to clarify proper methods for evaluating potential hazards of nitrate wastes.

  7. STATISTICAL PERFORMANCE EVALUATION OF SPRING OPERATED PRESSURE...

    Office of Scientific and Technical Information (OSTI)

    STATISTICAL PERFORMANCE EVALUATION OF SPRING OPERATED PRESSURE RELIEF VALVE RELIABILITY IMPROVEMENTS 2004 TO 2014 Citation Details In-Document Search Title: STATISTICAL PERFORMANCE ...

  8. Independent Oversight Evaluation, Office of Secure Transportation...

    Office of Environmental Management (EM)

    Emergency Management Program This report provides the results of an independent oversight evaluation of the emergency management program at the Department of Energy's (DOE) Office...

  9. Light Water Reactor Sustainability Nondestructive Evaluation...

    Energy Saver

    Nondestructive Evaluation for Concrete Research and Development Roadmap Light Water ... US Department of Energy Office of Nuclear Energy's Light Water Reactor Sustainability ...

  10. Clark Public Utilities Impact Evaluation Final Report

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Clark Public Utilities Impact Evaluation Final Report - July 2015 - Home Energy Reports Memorandum 1375 Walnut Street Suite 200 Boulder, CO 80302 303-728-2500 To: Lauren Gage...

  11. WEATHERIZATION ASSISTANCE PROGRAM NATIONAL EVALUATION: SUMMARY...

    Energy.gov [DOE] (indexed site)

    KEY EVALUATION OUTCOMES AND METRICS Energy Savings Renewable Generation Combined Energy Savings ... Generated 4.2 MMBtu from on-site Renewable Energy Projects Labor ...

  12. Evaluation Of Electrochemical Machining Technology For Surface...

    Office of Scientific and Technical Information (OSTI)

    Components Citation Details In-Document Search Title: Evaluation Of Electrochemical Machining Technology For Surface Improvements In Additive Manufactured Components ORNL ...

  13. Fuel Cell Transit Bus Coordination and Evaluation Plan California...

    Energy Saver

    Transit Bus Coordination and Evaluation Plan California Fuel Cell Transit Evaluation Team Fuel Cell Transit Bus Coordination and Evaluation Plan California Fuel Cell Transit ...

  14. Seismic Analysis of Facilities and Evaluation of Risk | Department...

    Office of Environmental Management (EM)

    Seismic Analysis of Facilities and Evaluation of Risk Seismic Analysis of Facilities and Evaluation of Risk Seismic Analysis of Facilities and Evaluation of Risk Michael Salmon,...

  15. Program Evaluation: EERE Resource Documents | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Information Resources Program Evaluation: EERE Resource Documents Program Evaluation: EERE Resource Documents Listed below are evaluation resource documents for the Office of ...

  16. United Parcel Service Evaluates Hybrid Electric Delivery Vans...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    ... United Parcel Service Evaluates Hybrid Electric Delivery Vans Advanced Vehicle Testing This project is part of a series of evaluations performed by NREL's Fleet Test and Evaluation ...

  17. General Evaluation SOP 6-26 2006 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    General Evaluation SOP 6-26 2006 General Evaluation SOP 6-26 2006 Quality Assurance for General Program Evaluation Studies PDF icon qaforgeneralprogevalstudies.pdf More ...

  18. Programs Planning to Do Evaluations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Programs Planning to Do Evaluations Better Buildings Neighborhood Program Data and Evaluation Peer Exchange Call: Programs Planning to Do Evaluations, Call Slides and Discussion ...

  19. PAE Evaluation Portfolio Peer Review | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    PAE Evaluation Portfolio Peer Review PAE Evaluation Portfolio Peer Review This is a report from the Peer Review Panel on activities within the Planning, Analysis and Evaluation ...

  20. Evaluation of Emerging Technology for Geothermal Drilling and...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Evaluation of Emerging Technology for Geothermal Drilling and Logging Applications Evaluation of Emerging Technology for Geothermal Drilling and Logging Applications Evaluation of ...

  1. ORISE: Workforce Analysis and Program Evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Workforce Analysis and Program Evaluation Workforce Analysis and Program Evaluation By accurately capturing statistics and conducting data analysis, the Oak Ridge Institute for Science and Education (ORISE) assesses the needs of the nation's science, technology, engineering and mathematics workforce. Our comprehensive workforce trends assessment and recruitment strategies enable us to match highly qualified participants with laboratories and agencies needing research assistance. Beyond research

  2. Evaluation of potential surface rupture and review of current seismic hazards program at the Los Alamos National Laboratory. Final report

    SciTech Connect

    Not Available

    1991-12-09

    This report summarizes the authors review and evaluation of the existing seismic hazards program at Los Alamos National Laboratory (LANL). The report recommends that the original program be augmented with a probabilistic analysis of seismic hazards involving assignment of weighted probabilities of occurrence to all potential sources. This approach yields a more realistic evaluation of the likelihood of large earthquake occurrence particularly in regions where seismic sources may have recurrent intervals of several thousand years or more. The report reviews the locations and geomorphic expressions of identified fault lines along with the known displacements of these faults and last know occurrence of seismic activity. Faults are mapped and categorized into by their potential for actual movement. Based on geologic site characterization, recommendations are made for increased seismic monitoring; age-dating studies of faults and geomorphic features; increased use of remote sensing and aerial photography for surface mapping of faults; the development of a landslide susceptibility map; and to develop seismic design standards for all existing and proposed facilities at LANL.

  3. Process Evaluation of the Better Buildings Neighborhood Program, Final Evaluation Volume 4

    Energy.gov [DOE]

    Final Report: Process Evaluation of the Better Buildings Neighborhood Program, Final Evaluation Volume 4, American Recovery and Reinvestment Act of 2009, June 2015. Prepared for U.S. Department of Energy Office of Energy Efficiency and Renewable Energy.

  4. Threatened and Endangered Species Evaluation for Operating Commercial Nuclear Power Generating Plants

    SciTech Connect

    Sackschewsky, Michael R.

    2004-01-15

    &E species take, consultations, and evaluations of potential effects of operation on T&E species. This search recovered a total of approximately 100 documents from 13 sites. Sites that were in the relicensing or decommissioning processes were excluded from the ADAMS search. In general the ADAMS search did not reveal any serious deficiencies or compliance problems. The most notable finds were reports of takes of green sea turtles at Diablo Canyon. While these events were reported to both the NRC and to NOAA Fisheries, no record of interaction between the two federal agencies was found. Species potentially present at each site were determined via querying the Geographical, Environmental, and Siting Information System (GEn&SIS) database developed for the NRC by Lawrence Livermore National Laboratory. The results of these queries were compared against the 1997 review, and in the cases of sites that were in the relicensing process, with the results of those site specific evaluations. A total of 452 T&E species were identified as potentially occurring near one or more of the operating commercial nuclear power generating plants. Information about each of these species was gathered to support an assessment of the probability of occurrence at each of the reactor sites. Based on the assessments of which species are potentially affected at each site, and the information gathered through the ADAMS search, each site was assigned a priority value for follow-up evaluations. The priority listing did not include any sites that had entered the relicensing process, those where the licensee has indicated that they intend to enter the relicensing process before the end of 2005, or those that have entered the decommissioning process. Of the 39 remaining sites, those that were identified as the highest priority for follow-on evaluations are: Diablo Canyon, San Onofre, Crystal River, Harris, and Vogtle, followed by South Texas, Palo Verde, Salem, and Cooper.

  5. EERE Guide for Managing General Program Evaluation Studies-- Appendix 11

    Energy.gov [DOE]

    The American Evaluation Association developed the ethical principles in this Appendix to guide the professional practice of evaluators. EERE expects evaluation experts who perform general program evaluations of its programs to be governed by these principles.

  6. Develop and Evaluate Materials and Additives that Enhance Thermal...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Develop & Evaluate Materials & Additives that Enhance Thermal & Overcharge Abuse Develop & Evaluate Materials & Additives that Enhance Thermal & Overcharge Abuse High Voltage ...

  7. Develop and Evaluate Materials and Additives that Enhance Thermal...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    More Documents & Publications Develop & evaluate materials & additives that enhance thermal & overcharge abuse Develop & Evaluate Materials & Additives that Enhance Thermal & ...

  8. Lawrence Livermore National Lab Perforemance Evaluations | National Nuclear

    National Nuclear Security Administration (NNSA)

    Security Administration | (NNSA) Lawrence Livermore National Lab Perforemance Evaluations FY 2016 FY 2016 Performance Evaluation Plan, Lawrence Livermore National Security, LLC FY 2015 FY 2015 Performance Evaluation Report, Lawrence Livermore National Security, LLC FY 2015 Performance Evaluation Report, Fee Determination Letter, Lawrence Livermore National Security, LLC FY 2015 Performance Evaluation Plan, Lawrence Livermore National Security, LLC FY 2014 FY 2014 Performance Evaluation

  9. Nevada National Security Site Performance Evaluations | National Nuclear

    National Nuclear Security Administration (NNSA)

    Security Administration | (NNSA) Nevada National Security Site Performance Evaluations FY 2016 FY 2016 Performance Evaluation Plan, National Security Technologies, LLC FY 2015 FY 2015 Performance Evaluation Report, National Security Technologies, LLC FY 2015 Performance Evaluation Report, Fee Determination Letter, National Security Technologies, LLC FY 2015 Performance Evaluation Plan, National Security Technologies, LLC FY 2014 FY 2014 Performance Evaluation Report, National Security

  10. SENIOR EXECUTIVE SERVICE CANDIDATE DEVELOPMENT PROGRAM (SESCDP...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Evaluation Form allows ESE candidates to evaluate assignments in terms of the executive core qualities the assignment was intended to meet, how well it met expectations and ...

  11. Management Alert - Extended Assignments at Princeton Plasma Physics...

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    ... MANAGEMENT REACTION AND AUDITOR COMMENTS The Office of Management concurred with our ... have been helpful? 5. Please include your name and telephone number so that we may ...

  12. Assigning protein functions by comparative genome analysis protein phylogenetic profiles

    DOEpatents

    Pellegrini, Matteo; Marcotte, Edward M.; Thompson, Michael J.; Eisenberg, David; Grothe, Robert; Yeates, Todd O.

    2003-05-13

    A computational method system, and computer program are provided for inferring functional links from genome sequences. One method is based on the observation that some pairs of proteins A' and B' have homologs in another organism fused into a single protein chain AB. A trans-genome comparison of sequences can reveal these AB sequences, which are Rosetta Stone sequences because they decipher an interaction between A' and B. Another method compares the genomic sequence of two or more organisms to create a phylogenetic profile for each protein indicating its presence or absence across all the genomes. The profile provides information regarding functional links between different families of proteins. In yet another method a combination of the above two methods is used to predict functional links.

  13. MB3a Infrasound Sensor Evaluation.

    SciTech Connect

    Merchant, Bion J.; McDowell, Kyle D.

    2014-11-01

    Sandia National Laboratories has tested and evaluated a new infrasound sensor, the MB3a, manufactured by Seismo Wave. These infrasound sensors measure pressure output by a methodology developed by researchers at the French Alternative Energies and Atomic Energy Commission (CEA) and the technology was recently licensed to Seismo Wave for production and sales. The purpose of the infrasound sensor evaluation was to determine a measured sensitivity, transfer function, power, self-noise, dynamic range, seismic sensitivity, and self- calibration ability. The MB3a infrasound sensors are being evaluated for potential use in the International Monitoring System (IMS) of the Comprehensive Nuclear Test-Ban-Treaty Organization (CTBTO).

  14. Smith Newton Vehicle Performance Evaluation - Cumulative (Brochure)

    SciTech Connect

    Not Available

    2014-08-01

    The Fleet Test and Evaluation Team at the U.S. Department of Energy's National Renewable Energy Laboratory is evaluating and documenting the performance of electric and plug-in hybrid electric drive systems in medium-duty trucks across the nation. U.S. companies participating in this evaluation project received funding from the American Recovery and Reinvestment Act to cover part of the cost of purchasing these vehicles. Through this project, Smith Electric Vehicles is building and deploying 500 all-electric medium-duty trucks that will be deployed by a variety of companies in diverse climates across the country.

  15. Energy Efficiency Program Impact Evaluation Guide

    Energy.gov [DOE]

    This Energy Efficiency Program Impact Evaluation Guide describes and provides guidance on approaches for determining and documenting energy and non-energy benefits resulting from end-use energy efficiency programs and portfolios of programs.

  16. ARM - Evaluation Product - Quality Controlled Eddy Correlation...

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    to hear from you Send us a note below or call us at 1-888-ARM-DATA. Send Evaluation Product : Quality Controlled Eddy Correlation Flux (QCECOR) Eddy correlation flux measurement...

  17. Program Evaluation: Rating Systems for Peer Reviews

    Energy.gov [DOE]

    Both the review panel and the presenters should clearly understand the objectives and guidelines for the review as well as the specific evaluation criteria that will be addressed. The review leader...

  18. RL's Fiscal Year 2013 Fee Evaluation Summary

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Evaluation and Measurement Plan (PEMP) Award Fee Available: 300,000.00 Award ... The FY 13 PEMP for this contract is available at: http:www.hanford.govfiles.cfm...

  19. State Energy Efficiency Program Evaluation Inventory

    Energy Information Administration (EIA) (indexed site)

    State Energy Efficiency Program Evaluation Inventory July 2013 Independent Statistics & Analysis www.eia.gov U.S. Department of Energy Washington, DC 20585 U.S. Energy Information ...

  20. National Uranium Resource Evaluation, Tonopah quadrangle, Nevada

    SciTech Connect

    Hurley, B W; Parker, D P

    1982-04-01

    The Tonopah Quadrangle, Nevada, was evaluated using National Uranium Resource Evaluation criteria to identify and delineate areas favorable for uranium deposits. Investigations included reconnaissance and detailed surface geologic and radiometric studies, geochemical sampling and evaluation, analysis and ground-truth followup of aerial radiometric and hydrogeochemical and stream-sediment reconnaissance data, and subsurface data evaluation. The results of these investigations indicate environments favorable for hydroallogenic uranium deposits in Miocene lacustrine sediments of the Big Smoky Valley west of Tonopah. The northern portion of the Toquima granitic pluton is favorable for authigenic uranium deposits. Environments considered unfavorable for uranium deposits include Quaternary sediments; intermediate and mafic volcanic and metavolcanic rocks; Mesozoic, Paleozoic, and Precambrian sedimentary and metasedimentary rocks; those plutonic rocks not included within favorable areas; and those felsic volcanic rocks not within the Northumberland and Mount Jefferson calderas.

  1. ARM - Evaluation Product - Aerosol Modeling Testbed

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    The Aerosol Modeling Testbed (AMT) is a means of organizing a wide range of measurements into a single data set that modelers can use to evaluate the performance of aerosol, ...

  2. ARM - Field Campaign - Microwave Radiometer Profiler Evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    govCampaignsMicrowave Radiometer Profiler Evaluation ARM Data Discovery Browse Data Comments? We would love to hear from you Send us a note below or call us at 1-888-ARM-DATA....

  3. CRAD, NNSA- Evaluating Contractor Assurance Systems

    Energy.gov [DOE]

    CRAD for Evaluating Contractor Assurance Systems. Criteria Review and Approach Documents (CRADs) that can be used to conduct a well-organized and thorough assessment of elements of safety and health programs.

  4. Performance Evaluation of Undulator Radiation at CEBAF

    SciTech Connect

    Chuyu Liu, Geoffrey Krafft, Guimei Wang

    2010-05-01

    The performance of undulator radiation (UR) at CEBAF with a 3.5 m helical undulator is evaluated and compared with APS undulator-A radiation in terms of brilliance, peak brilliance, spectral flux, flux density and intensity distribution.

  5. Yosemite Waters Vehicle Evaluation Report: Final Results

    SciTech Connect

    Eudy, L.; Barnitt, R.; Alleman, T. L.

    2005-08-01

    Document details the evaluation of Fischer-Tropsch diesel, a gas-to-liquid fuel, in medium-duty delivery vehicles at Yosemite Waters. The study was conducted by NREL at the company's Fullerton, California, bottling headquarters.

  6. General Evaluation SOP 6-26 2006

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    1.3 Policy: It is EERE's policy to: 1.3.1 Ensure an objective and independent evaluation process is used in a ... published and made public Program office review of ...

  7. Environmental evaluation of Surface Mounted Devices (SMD)

    SciTech Connect

    Barr, V.C.; Andrade, A.D.

    1997-06-01

    We evaluated the comparative reliability of solder interconnections used for Leadless Chip Carriers (LCCs), Meaded, and flat-pack hybrid microcircuits mounted on FR-4 glass epoxy printed wiring boards (PWBs). The board assemblies, with solder attached microcircuits, were repeatedly thermal cycled from - 65 to +125{degrees}C. We recognize that this temperature range far exceeds most testing of assemblies. The purposes of these tests were to evaluate worst-case conditions and to obtain comparative information. Identical PWB assemblies, using these three component types, were subjected to both thermal shock testing (1 cycle every 42 minutes) and temperature cycle testing (1 cycle every 3 hours). The double testing evaluated the differences in stress application and evaluated the potential of replacing slow transition, expensive temperature cycle testing (which has been an industry standard for years) with the much more rapid thermal shock testing.

  8. Annual Merit Review and Peer Evaluation Report

    SciTech Connect

    2012-03-16

    Each year, hydrogen and fuel cell projects funded by DOE's Hydrogen and Fuel Cells Program are reviewed for their merit during an Annual Merit Review and Peer Evaluation Meeting.

  9. Vehicle Technologies Office: AVTA - Evaluating Military Bases...

    Energy.gov [DOE] (indexed site)

    military to evaluate readiness for plug-in electric vehicles. Electric Vehicle Preparedness: Assessment of Data and Survey Results for Join Base Lewis McChord (1.17 MB) Electric ...

  10. An evaluation of enhanced geothermal systems technology

    SciTech Connect

    None, None

    2009-01-18

    A review of the assumptions and conclusions of the DOE-sponsored 2006 MIT study on "The Future of Geothermal Energy" and an evaluation of relevant technology from the commercial geothermal industry.

  11. Program Evaluation: Glossary | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    ... Internal Validity. The extent to which the causes of an effect are established by an inquiry. (GAO, Designing Evaluations 1991, p. 92) Back to Top L Logic Model. A plausible and ...

  12. NREL: Energy Storage - Energy Storage Systems Evaluation

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Energy Storage Systems Evaluation Photo of man standing between two vehicles and plugging the vehicle on the right into a charging station. NREL system evaluation has confirmed that extreme climates can have a dramatic impact on batteries and energy storage systems. Graph with numerous plots showing battery capacity and resistance with drive time data spanning a two-year period. An NREL algorithm is being used to extract battery state-of-health information and degradation trends from BMW Mini-E

  13. Laboratory performance evaluation reports for management

    SciTech Connect

    Lindahl, P.C.; Hensley, J.E.; Bass, D.A.; Johnson, P.L.; Marr, J.J.; Streets, W.E.; Warren, S.W.; Newberry, R.W.

    1995-05-01

    In support of the US DOE`s environmental restoration efforts, the Integrated Performance Evaluation Program (IPEP) was developed to produce laboratory performance evaluation reports for management. These reports will provide information necessary to allow DOE headquarters and field offices to determine whether or not contracted analytical laboratories have the capability to produce environmental data of the quality necessary for the remediation program. This document describes the management report.

  14. Columbia River Component Data Evaluation Summary Report

    SciTech Connect

    C.S. Cearlock

    2006-08-02

    The purpose of the Columbia River Component Data Compilation and Evaluation task was to compile, review, and evaluate existing information for constituents that may have been released to the Columbia River due to Hanford Site operations. Through this effort an extensive compilation of information pertaining to Hanford Site-related contaminants released to the Columbia River has been completed for almost 965 km of the river.

  15. On the exact evaluation of spin networks

    SciTech Connect

    Freidel, Laurent; Hnybida, Jeff; Department of Physics, University of Waterloo, Waterloo, Ontario N2L 3G1

    2013-11-15

    We introduce a fully coherent spin network amplitude whose expansion generates all SU(2) spin networks associated with a given graph. We then give an explicit evaluation of this amplitude for an arbitrary graph. We show how this coherent amplitude can be obtained from the specialization of a generating functional obtained by the contraction of parametrized intertwiners la Schwinger. We finally give the explicit evaluation of this generating functional for arbitrary graphs.

  16. Single-Shell Tank Evaluations - Hanford Site

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Single-Shell Tank Evaluations Documents Documents Hanford Site Cleanup Completion Framework Tri-Party Agreement Freedom of Information and Privacy Act Hanford Site Budget Hanford Site Safety Standards DOE - ORP Contracts/Procurements DOE - RL Contracts/Procurements Integrated Waste Feed Delivery Plan Single-Shell Tank Evaluations Deep Vadose Zone 100-F RI/FS 100-D/H Operable Units RI/FS Sitewide Probabilistic Seismic Hazard Analysis Environmental Email Email Page | Print Print Page | Text

  17. Evaluation Report: IG-0519 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    19 Evaluation Report: IG-0519 August 30, 2001 Evaluation of the Department's Unclassified Cyber Security Program Protecting unclassified information systems continues to be one of the top issues facing Government organizations today. While the increase in computer interconnectivity, most notably growth in the use of the Internet, has revolutionized the way the Government does business, it has also significantly increased the risk of damage to information systems by malicious or unauthorized

  18. Evaluation of the Better Buildings Neighborhood Program

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    202 Prepared For: U.S. Department of Energy Office of Energy Efficiency and Renewable Energy Final Report Evaluation of the Better Buildings Neighborhood Program Final Synthesis Report, Volume 1 American Recovery and Reinvestment Act of 2009 June 2015 Prepared For: U.S. Department of Energy Office of Energy Efficiency and Renewable Energy DOE/EE-1202 DOE/EE-1202 Final Report Evaluation of the Better Buildings Neighborhood Program Final Synthesis Report, Volume 1 American Recovery and

  19. Smith Newton Vehicle Performance Evaluation (Brochure)

    SciTech Connect

    Not Available

    2012-08-01

    The Fleet Test and Evaluation Team at the U.S. Department of Energy's National Renewable Energy Laboratory is evaluating and documenting the performance of electric and plug-in hybrid electric drive systems in medium-duty trucks across the nation. Through this project, Smith Electric Vehicles will build and deploy 500 all-electric medium-duty trucks. The trucks will be deployed in diverse climates across the country.

  20. Evaluation and Selection of CSES Proposals

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Evaluating, Selecting Proposals Evaluation and Selection of CSES Proposals High quality, cutting-edge science in the areas of astrophysics, space physics, solid planetary geoscience, and climate science Contact Director Reiner Friedel (505) 665-1936 Email Professional Staff Assistant Georgia D. Sanchez (505) 665-0855 Email Geophysics W. Scott Baldridge (505) 667-4338 Email New student and postdoc proposals All new proposals undergo peer review by scientists in the broad research community who

  1. National Fuel Cell Technology Evaluation Center (NFCTEC)

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    National Fuel Cell Technology Evaluation Center (NFCTEC) Jim Alkire U.S. Department of Energy Fuel Cell Technologies Office Jennifer Kurtz & Sam Sprik National Renewable Energy Laboratory 2 Outline * About NFCTEC * Benefits to the Hydrogen & Fuel Cell Community * New Fuel Cell Cost/Price Aggregation Project About NFCTEC 4 National Fuel Cell Technology Evaluation Center a national resource for hydrogen and fuel cell stakeholders supported through Energy Efficiency and Renewable Energy's

  2. Energy Efficiency Program Impact Evaluation Guide

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Program Impact Evaluation Guide Evaluation, Measurement, and Verification Working Group December 2012 The State and Local Energy Efficiency Action Network is a state and local effort facilitated by the federal government that helps states, utilities, and other local stakeholders take energy efficiency to scale and achieve all cost-effective energy efficiency by 2020. Learn more at www.seeaction.energy.gov DOE/EE-0829 ii December 2012 www.seeaction.energy.gov ABOUT THIS DOCUMENT This Energy

  3. Update on Status of SEP National Evaluation

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Update for State Energy Advisory Board on Status of SEP National Evaluation Martin Schweitzer Oak Ridge National Laboratory June 26, 2012 Managed by UT-Battelle for the Department of Energy Introduction * Study is being performed by independent evaluation team (KEMA, Inc. and subcontractors) and managed by ORNL * Will quantify energy and cost savings, job creation, renewable energy generation, and carbon emissions reductions * Covers program year 2008 and ARRA period 2 Managed by UT-Battelle for

  4. 300 Area Building Retention Evaluation Mitigation Plan

    SciTech Connect

    D. J. McBride

    2007-07-03

    Evaluate the long-term retention of several facilities associated with the PNNL Capability Replacement Laboratory and other Hanfor mission needs. WCH prepared a mitigation plan for three scenarios with different release dates for specific buildings. The evaluations present a proposed plan for providing utility services to retained facilities in support of a long-term (+20 year) lifespan in addition to temporary services to buildings with specified delayed release dates.

  5. Program Evaluation: Purpose and Costs | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    Purpose and Costs Program Evaluation: Purpose and Costs Steps one through three will help you establish the purpose of and determine which resources are available for your evaluation (learn more about the other steps in general program evaluations): Step 1: Decide the Evaluation Objectives Step 2: Determine Resources Available Step 3: Determine the Timeline for Completing the Evaluation Step 1: Decide the Evaluation Objectives Evaluation objectives are determined by careful consideration of the

  6. Hanford Site storm water comprehensive site compliance evaluation report for the reporting period July 1, 1996 through June 30, 1997

    SciTech Connect

    Perkins, C.J.

    1997-09-18

    On September 9, 1992, the US Environmental Protection Agency (EPA) issued General Permit No. WA-R-00-OOOF, Authorization to Discharge Under the National Pollutant Discharge Elimination System (NPDES) for Storm Water Discharges Associated with Industrial Activity to the US Department of Energy, Richland Operations Office (RL). RL submitted a Notice of Intent to comply with this permit to EPA in conformance with the General Permit requirements on October 1, 1992. On February 14, 1994, EPA issued a Storm Water General Permit Coverage Notice and assigned WA-R-00-Al7F as the Hanford Site`s National Pollutant Discharge Elimination System (NPDES) storm water permit number. The Hanford Site Storm Water Pollution Prevention Plan (SWPPP) (WHC 1996a) was certified by J. E Rasmussen, Director Environmental Assurance, RL, on September 24, 1996, in compliance with Part IV.B(i) of the General Permit. As required by General Permit No. WA-R-00-OOOF (WA-R-00-Al7F), Section IV, Part D, Section 4.c, an annual report must be developed by RL and retained on site to verify that the requirements listed in the General Permit are being implemented. The previous Hanford Site Storm Plater Comprehensive Site Compliance Evaluation Report (WHC 1996b) addressed the period from July 1995 through June 1996. This document fulfills the requirement to prepare an annual report and contains the results of inspections of the storm water outfalls listed in the SWPPP (WHC 1996a). This report also describes the methods used to conduct the 1100 Storm Plater Comprehensive Site Compliance Evaluation (SWCSCE) as required in Part IV, Section D.4.c in the General Permit; summarizes the results of the compliance evaluation; and documents significant leaks and spills. The reporting year for this SWCSCE report is July 1, 1996 through June 30, 1997.

  7. Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    the U.S. Department of Energy and the Federal Transit Administration | Department of Energy Administration Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for the U.S. Department of Energy and the Federal Transit Administration This document describes the hydrogen transit bus evaluations performed by the National Renewable Energy Laboratory (NREL) and funded by the U.S. Department of Energy (DOE) and the U.S. Department of Transportation's Federal Transit Administration

  8. Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for

    Office of Energy Efficiency and Renewable Energy (EERE) (indexed site)

    the U.S. Department of Energy and the Federal Transit Administration; Appendix | Department of Energy Administration; Appendix Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for the U.S. Department of Energy and the Federal Transit Administration; Appendix This document describes the hydrogen transit bus evaluations performed by the National Renewable Energy Laboratory (NREL) and funded by the U.S. Department of Energy (DOE) and the U.S. Department of Transportation's

  9. Gasbuggy Site Assessment and Risk Evaluation

    SciTech Connect

    2011-03-01

    This report describes the geologic and hydrologic conditions and evaluates potential health risks to workers in the natural gas industry in the vicinity of the Gasbuggy, New Mexico, site, where the U.S. Atomic Energy Commission detonated an underground nuclear device in 1967. The 29-kiloton detonation took place 4,240 feet below ground surface and was designed to evaluate the use of a nuclear detonation to enhance natural gas production from the Pictured Cliffs Formation in the San Juan Basin, Rio Arriba County, New Mexico, on land administered by Carson National Forest. A site-specific conceptual model was developed based on current understanding of the hydrologic and geologic environment. This conceptual model was used for establishing plausible contaminant exposure scenarios, which were then evaluated for human health risk potential. The most mobile and, therefore, the most probable contaminant that could result in human exposure is tritium. Natural gas production wells were identified as having the greatest potential for bringing detonation-derived contaminants (tritium) to the ground surface in the form of tritiated produced water. Three exposure scenarios addressing potential contamination from gas wells were considered in the risk evaluation: a gas well worker during gas-well-drilling operations, a gas well worker performing routine maintenance, and a residential exposure. The residential exposure scenario was evaluated only for comparison; permanent residences on national forest lands at the Gasbuggy site are prohibited

  10. MOV reliability evaluation and periodic verification scheduling

    SciTech Connect

    Bunte, B.D.

    1996-12-01

    The purpose of this paper is to establish a periodic verification testing schedule based on the expected long term reliability of gate or globe motor operated valves (MOVs). The methodology in this position paper determines the nominal (best estimate) design margin for any MOV based on the best available information pertaining to the MOVs design requirements, design parameters, existing hardware design, and present setup. The uncertainty in this margin is then determined using statistical means. By comparing the nominal margin to the uncertainty, the reliability of the MOV is estimated. The methodology is appropriate for evaluating the reliability of MOVs in the GL 89-10 program. It may be used following periodic testing to evaluate and trend MOV performance and reliability. It may also be used to evaluate the impact of proposed modifications and maintenance activities such as packing adjustments. In addition, it may be used to assess the impact of new information of a generic nature which impacts safety related MOVs.

  11. National uranium resource evaluation. Winnemucca Quadrangle, Nevada

    SciTech Connect

    Berridge, W.C.; Wolverson, N.J.

    1982-05-01

    The Winnemucca 2/sup 0/ quadrangle, Nevada, was evaluated for geologic environments favorable for uranium deposits, using criteria developed for the National Uranium Resource Evaluation program. Reconnaissance radiometric and geochemical surveys were conducted for all geologic environments open to evaluation. Detailed surface and subsurface investigations were conducted in potential host and source environments. Subsurface data collected by private industry were obtained for favorable environments. The results of this investigation indicate environments favorable for hydroallogenic uranium deposits in the Fish Creek Basin sedimentary rocks of Miocene age, and for hydroallogenic and sandstone uranium deposits in the Home Station Wash sedimentary rocks of Miocene age. Environments in the quadrangle considered unfavorable for uranium deposits are exposed sedimentary rocks of Precambrian, Paleozoic, Mesozoic, and Tertiary ages (other than those in the Fish Creek Basin and Home Station Wash areas); Mesozoic and Tertiary plutonic rocks; and Mesozoic and Tertiary volcanic rocks. Substantial portions of the quadrangle remain unevaluated because of restricted access or insufficient subsurface data.

  12. Evaluation of radioactive scrap metal recycling

    SciTech Connect

    Nieves, L.A.; Chen, S.Y.; Kohout, E.J.; Nabelssi, B.; Tilbrook, R.W.; Wilson, S.E.

    1995-12-01

    This report evaluates the human health risks and environmental and socio-political impacts of options for recycling radioactive scrap metal (RSM) or disposing of and replacing it. Argonne National Laboratory (ANL) is assisting the US Department of Energy (DOE), Office of Environmental Restoration and Waste Management, Oak Ridge Programs Division, in assessing the implications of RSM management alternatives. This study is intended to support the DOE contribution to a study of metal recycling being conducted by the Task Group on Recycling and Reuse of the Organization for Economic Cooperation and Development. The focus is on evaluating the justification for the practice of recycling RSM, and the case of iron and steel scrap is used as an example in assessing the impacts. To conduct the evaluation, a considerable set of data was compiled and developed. Much of this information is included in this document to provide a source book of information.

  13. High-speed electrical motor evaluation

    SciTech Connect

    Not Available

    1989-02-03

    Under this task, MTI conducted a general review of state-of-the-art high-speed motors. The purpose of this review was to assess the operating parameters, limitations and performance of existing motor designs, and to establish commercial sources for a motor compatible with the requirements of the Brayton-cycle system. After the motor requirements were established, a list of motor types, manufacturers and designs capable of achieving the requisite performance was compiled. This list was based on an in-house evaluation of designs. Following the establishment of these options, a technical evaluation of the designs selected was conducted. In parallel with their evaluations, MTI focused on the establishment of commercial sources.

  14. Supplier Performance Evaluation and Rating System (SPEARS)

    SciTech Connect

    Oged, M.; Warner, D.; Gurbuz, E.

    1993-03-01

    The SSCL Magnet Quality Assurance Department has implemented a Supplier Performance Evaluation and Rating System (SPEARS) to assess supplier performance throughout the development and production stages of the SSCL program. The main objectives of SPEARS are to promote teamwork and recognize performance. This paper examines the current implementation of SPEARS. MSD QA supports the development and production of SSCsuperconducting magnets while implementing the requirements of DOE Order 5700.6C. The MSD QA program is based on the concept of continuous improvement in quality and productivity. The QA program requires that procurement of items and services be controlled to assure conformance to specification. SPEARS has been implemented to meet DOE requirements and to enhance overall confidence in supplier performance. Key elements of SPEARS include supplier evaluation and selection as well as evaluation of furnished quality through source inspection, audit, and receipt inspection. These elements are described in this paper.

  15. Handbook of evaluation of utility DSM programs

    SciTech Connect

    Hirst, E.; Reed, J.; Bronfman, B.; Fitzpatrick, G.; Hicks, E.; Hirst, E.; Hoffman, M.; Keating, K.; Michaels, H.; Nadel, S.; Peters, J.; Reed, J.; Saxonis, W.; Schoen, A.; Violette, D.

    1991-12-01

    Program evaluation has become a central issue in the world of utility integrated resource planning. The DSM programs that utilities were operating to meet federal requirements or to improve customer relations are now becoming big business. DSM is being considered an important resource in a utility`s portfolio of options. In the last five years, the amount of money that utilities have invested in DSM has grown exponentially in most regulatory jurisdictions. Market analysts are now talking about DSM being a $30 billion industry by the end of the decade. If the large volume of DSM-program investments was not enough to highlight the importance of evaluation, then the introduction of regulatory incentives has really focused the spotlight. This handbook was developed through a process that involved many of those people who represent the diverse constituencies of DSM-program evaluation. We have come to recognize the many technical disciplines that must be employed to evaluate DSM programs. An analysis might start out based on the principles of utility load research to find out what happened, but a combination of engineering and statistical methods must be used to ``triangulate`` an estimate of what would have happened without the program. The difference, of course, is that elusive but prized result of evaluation: what happened as the direct result of the DSM program. Technical performance of DSM measures is not the sole determinant of the answer, either. We also recognize the importance of such behavioral attributes of DSM as persistence and free ridership. Finally, DSM evaluation is meaningless without attention to planning an approach, communicating results to relevant decision-makers, and focusing as much on the process as the impacts of the program. These topics are all covered in this handbook.

  16. NHI Component Technical Readiness Evaluation System

    SciTech Connect

    Steven R. Sherman; Dane F. Wilson; Steven J. Pawel

    2007-09-01

    A decision process for evaluating the technical readiness or maturity of components (i.e., heat exchangers, chemical reactors, valves, etc.) for use by the U.S. DOE Nuclear Hydrogen Initiative is described. This system is used by the DOE NHI to assess individual components in relation to their readiness for pilot-scale and larger-scale deployment and to drive the research and development work needed to attain technical maturity. A description of the evaluation system is provided, and examples are given to illustrate how it is used to assist in component R&D decisions.

  17. Performance evaluation soil samples utilizing encapsulation technology

    DOEpatents

    Dahlgran, James R.

    1999-01-01

    Performance evaluation soil samples and method of their preparation using encapsulation technology to encapsulate analytes which are introduced into a soil matrix for analysis and evaluation by analytical laboratories. Target analytes are mixed in an appropriate solvent at predetermined concentrations. The mixture is emulsified in a solution of polymeric film forming material. The emulsified solution is polymerized to form microcapsules. The microcapsules are recovered, quantitated and introduced into a soil matrix in a predetermined ratio to form soil samples with the desired analyte concentration.

  18. Performance evaluation soil samples utilizing encapsulation technology

    DOEpatents

    Dahlgran, J.R.

    1999-08-17

    Performance evaluation soil samples and method of their preparation uses encapsulation technology to encapsulate analytes which are introduced into a soil matrix for analysis and evaluation by analytical laboratories. Target analytes are mixed in an appropriate solvent at predetermined concentrations. The mixture is emulsified in a solution of polymeric film forming material. The emulsified solution is polymerized to form microcapsules. The microcapsules are recovered, quantitated and introduced into a soil matrix in a predetermined ratio to form soil samples with the desired analyte concentration. 1 fig.

  19. Graphical methods for evaluating covering arrays

    SciTech Connect

    Kim, Youngil; Jang, Dae -Heung; Anderson-Cook, Christine M.

    2015-08-10

    Covering arrays relax the condition of orthogonal arrays by only requiring that all combination of levels be covered but not requiring that the appearance of all combination of levels be balanced. This allows for a much larger number of factors to be simultaneously considered but at the cost of poorer estimation of the factor effects. To better understand patterns between sets of columns and evaluate the degree of coverage to compare and select between alternative arrays, we suggest several new graphical methods that show some of the patterns of coverage for different designs. These graphical methods for evaluating covering arrays are illustrated with a few examples.

  20. Hanford Site Comprehensive site Compliance Evaluation Report

    SciTech Connect

    Tollefson, K.S.

    1997-08-05

    This document is the second annual submittal by WHC, ICF/KH, PNL and BHI and contains the results of inspections of the stormwater outfalls listed in the Hanford Site Storm Water Pollution Prevention Plan (SWPPP) (WHC 1993a) as required by General Permit No. WA-R-00-000F (WA-R-00-A17F): This report also describes the methods used to conduct the Storm Water Comprehensive Site Compliance Evaluation, as required in Part IV, Section D, {ampersand} C of the General Permit, summarizes the results of the compliance evaluation, and documents significant leaks and spills.