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DOE and Human Genome Research

Charles DeLisi


The U.S. Department of Energy (DOE) has historically played a leading role in supporting human genome research.  March 2014 is the anniversary of the 1986 Santa Fe Workshop, which brought together participants from government, academia, and the private sector to explore the possibility of sequencing the human genome.  This workshop was sponsored by DOE and Los Alamos National Laboratory (LANL).  The Human Genome Project (HGP) was formalized in mid-February 1990.

In honor of the anniversary of the Santa Fe Workshop, DOE R&D Accomplishments has published a new feature page, Human Genome Research: DOE Origins.  This page describes the key role played by Charles DeLisi, then Associate Director of the Department of Energy’s (DOE) Office of Health and Environmental Research (OHER) in conceiving the idea for a program to sequence the human genome.  The Santa Fe Workshop met DeLisi’s goal of laying out an approach to sequence the human genome. 

This new feature page complements a previously published DOE R&D Accomplishments feature page, Human Genome Research: Decoding DNA.  By April 2000, DOE researchers had decoded in draft form the genetic information on human chromosomes 5, 16, and 19, or an estimated 11 percent of the total human genome.  In June of that year, a ‘working draft’ that included a road map to an estimated 90% of the genes on every chromosome was announced. 

Each of these feature pages...

Related Topics: Charles DeLisi, DNA, genomics, Human Genome Project, Santa Fe Workshop, sequencing, DOE Research & Development (R&D) Accomplishments