Creation of synthetic host molecules led to 1987 Nobel Prize for Cram

Twenty years after creating synthetic host molecules that mimic some of the actions that enzymes perform in cells, Donald Cram was awarded the 1987 Nobel Prize in Chemistry. In his host-guest research, Cram and his colleagues designed and prepared more than 1,000 hosts -- each with unique chemical and physical properties -- designed to attract and bind (to serve as hosts) to specific guest molecules, which can be either organic molecules or inorganic ions. Get resources with additional information including full-text documents, and see the research highlights at the OSTI DOE R&D Accomplishments website. DOE R&D Accomplishments is a central forum for information about significant outcomes of past DOE R&D widely recognized as remarkable advancements in science.

Last updated on Monday 25 April 2016