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Local cerebral metabolic rate of glucose (lCMRGlc) in treated and untreated patients with Parkinson's disease

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Abstract

Local cerebral metabolic rate of glucose (lCMRGlc) was measured twice, using positron emission tomography and /sup 18/F-Fluoro-2-deoxy-D-glucose (/sup 18/FDG), in 4 patients with Parkinson disease, first unmedicated and then treated with L-DOPA. Despite a dramatic clinical improvement, no significant changes in lCMRGlc could be detected. Moreover, no reproducible differences of lCMRGlc were found between patients with Parkinson disease and with normal brain.
Authors:
Publication Date:
Jun 01, 1983
Product Type:
Conference
Report Number:
CEA-CONF-6843; CONF-8306151-3
Reference Number:
FR-83-03561; ERA-09-012784; EDB-84-038032
Resource Relation:
Conference: 11. international symposium on cerebral blood flow and metabolism, Paris, France, 20 Jun 1983; Other Information: Portions are illegible in microfiche products
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CEREBRUM; POSITRON COMPUTED TOMOGRAPHY; GLUCOSE; METABOLISM; ANTIMETABOLITES; DOPA; FLUORINE 18; NERVOUS SYSTEM DISEASES; RADIOPHARMACEUTICALS; ALDEHYDES; AMINO ACIDS; AUTONOMIC NERVOUS SYSTEM AGENTS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; BRAIN; CARBOHYDRATES; CARBOXYLIC ACIDS; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HEXOSES; HOURS LIVING RADIOISOTOPES; HYDROXY ACIDS; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MONOSACCHARIDES; NERVOUS SYSTEM; NEUROREGULATORS; NUCLEI; ODD-ODD NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPES; SACCHARIDES; TOMOGRAPHY; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
8293463
Research Organizations:
CEA Centre d'Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)
Country of Origin:
France
Language:
English
Other Identifying Numbers:
Other: ON: DE84750447
Availability:
NTIS (US Sales Only), PC A02/MF A01; 1.
Submitting Site:
FR
Size:
Pages: 3
Announcement Date:
Dec 01, 1983

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Citation Formats

Rougemont, D, Baron, J C, Collard, P, Bustany, P, Comar, D, and Agid, Y. Local cerebral metabolic rate of glucose (lCMRGlc) in treated and untreated patients with Parkinson's disease. France: N. p., 1983. Web.
Rougemont, D, Baron, J C, Collard, P, Bustany, P, Comar, D, & Agid, Y. Local cerebral metabolic rate of glucose (lCMRGlc) in treated and untreated patients with Parkinson's disease. France.
Rougemont, D, Baron, J C, Collard, P, Bustany, P, Comar, D, and Agid, Y. 1983. "Local cerebral metabolic rate of glucose (lCMRGlc) in treated and untreated patients with Parkinson's disease." France.
@misc{etde_8293463,
title = {Local cerebral metabolic rate of glucose (lCMRGlc) in treated and untreated patients with Parkinson's disease}
 author = {Rougemont, D, Baron, J C, Collard, P, Bustany, P, Comar, D, and Agid, Y}
 abstractNote = {Local cerebral metabolic rate of glucose (lCMRGlc) was measured twice, using positron emission tomography and /sup 18/F-Fluoro-2-deoxy-D-glucose (/sup 18/FDG), in 4 patients with Parkinson disease, first unmedicated and then treated with L-DOPA. Despite a dramatic clinical improvement, no significant changes in lCMRGlc could be detected. Moreover, no reproducible differences of lCMRGlc were found between patients with Parkinson disease and with normal brain.}
 place = {France}
 year = {1983}
 month = {Jun}
 }