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Neurological aspects of lead intoxication

Technical Report:

Abstract

This study gives a survey over the medical and scientific literature on lead intoxications, which were published until 1979. Neurologic aspects are of particular interest. At present dramatic cases of lead intoxications occur only rarely. However, there are numerous studies about cases of chronical, partly subclinical intoxications. This chronical type of lead intoxication can become manifest clinically as relatively vague symptoms, for example vertigos, insomnia, headaches and weakness. Contrary to this, serious encephalopathies, even with fatal outcome, and polyneuropathies with typical paresis of the radial nerve are preferably observed in acute lead intoxications. Besides the numerous sources of intoxication, also the different opinions found in literature are discussed, concerning the effects of lead on the human body. The fact that there are differing opinions about the limiting value of the blood-lead level at which intoxication symptoms have to be expected, becomes apparent when the determined blood-lead level values are compared and evaluated. Besides the description of general intoxication effects, the discussion of the neurologic aspects found in literature - not only those concerning the central, but also the peripheral system - are preferably concerned. Reports about neuropsychical alterations due to lead exposure, which are mainly found in children, supplement the  More>>
Authors:
Publication Date:
May 08, 1980
Product Type:
Technical Report
Report Number:
NP-3770115
Reference Number:
ERA-08-034626; EDB-83-105932
Resource Relation:
Other Information: Portions are illegible in microfiche products. Thesis
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; LEAD; BIOLOGICAL EFFECTS; TOXICITY; NERVOUS SYSTEM DISEASES; AGE GROUPS; BEHAVIOR; BLOOD; HUMAN POPULATIONS; MAN; NERVOUS SYSTEM; NEUROLOGY; QUANTITY RATIO; REVIEWS; RURAL AREAS; URBAN AREAS; ANIMALS; BIOLOGICAL MATERIALS; BODY FLUIDS; DISEASES; DOCUMENT TYPES; ELEMENTS; MAMMALS; MATERIALS; MEDICINE; METALS; POPULATIONS; PRIMATES; VERTEBRATES; 560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
OSTI ID:
8134031
Research Organizations:
Muenchen Univ. (Germany, F.R.). Fachbereich Medizin
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Other: ON: DE83770115
Availability:
NTIS (US Sales Only), PC A08/MF A01; 1.
Submitting Site:
HEDB
Size:
Pages: 154
Announcement Date:
Mar 14, 2013

Technical Report:

Citation Formats

Lehner, H. Neurological aspects of lead intoxication. Germany: N. p., 1980. Web.
Lehner, H. Neurological aspects of lead intoxication. Germany.
Lehner, H. 1980. "Neurological aspects of lead intoxication." Germany.
@misc{etde_8134031,
title = {Neurological aspects of lead intoxication}
author = {Lehner, H}
abstractNote = {This study gives a survey over the medical and scientific literature on lead intoxications, which were published until 1979. Neurologic aspects are of particular interest. At present dramatic cases of lead intoxications occur only rarely. However, there are numerous studies about cases of chronical, partly subclinical intoxications. This chronical type of lead intoxication can become manifest clinically as relatively vague symptoms, for example vertigos, insomnia, headaches and weakness. Contrary to this, serious encephalopathies, even with fatal outcome, and polyneuropathies with typical paresis of the radial nerve are preferably observed in acute lead intoxications. Besides the numerous sources of intoxication, also the different opinions found in literature are discussed, concerning the effects of lead on the human body. The fact that there are differing opinions about the limiting value of the blood-lead level at which intoxication symptoms have to be expected, becomes apparent when the determined blood-lead level values are compared and evaluated. Besides the description of general intoxication effects, the discussion of the neurologic aspects found in literature - not only those concerning the central, but also the peripheral system - are preferably concerned. Reports about neuropsychical alterations due to lead exposure, which are mainly found in children, supplement the numerous descriptions of the macroscopic and microscopic alterations of the nervous system provoked by lead. Finally the therapeutic and prophylactic measures given in the literature are discussed.}
place = {Germany}
year = {1980}
month = {May}
}