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Inactivation of bacterial cells by cyclotron beams

Abstract

B. subtilis spores, E. coli Bsub(s-1) and E. coli B/r were bombarded with ..cap alpha..-particles and heavy ions of carbon, nitrogen and oxygen accelerated in the IPCR Cyclotron. The RBE versus LETsub(infinity) curve for B. subtilis spores showed a maximum peak at 120 keV/..mu..m, while those for E. coli Bsub(s-1) and E. coli B/r declined without any maximum as LETsub(infinity) values increased. In the region of ..cap alpha..-particles, the effective inactivation cross section (Ssub(eff)) for these three strains increased with increasing LETsub(infinity), and the rates of increase in Ssub(eff) in the LET region from --30 to --150 keV/..mu..m were 15.0, 1.5 and 2.5 times for B. subtilis spores, E. coli Bsub(s-1) and E. coli B/r, respectively. In the case of B. subtilis spores, Ssub(eff) values for heavy ions were almost independent of their energies, but the other two strains showed a considerable dependence upon beam energy. The characteristic LET dependence of Ssub(eff) observed in this study was fairly well explained by the target theory based on microdose concept.
Authors:
Yatagai, F; [1]  Takahashi, T; Matsuyama, A
  1. Waseda Univ., Tokyo (Japan). School of Science and Engineering
Publication Date:
Jun 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-248447; EDB-76-076841
Resource Relation:
Journal Name: J. Radiat. Res.; (Japan); Journal Volume: 16:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BACILLUS SUBTILIS; BIOLOGICAL RADIATION EFFECTS; BACTERIAL SPORES; ESCHERICHIA COLI; ALPHA PARTICLES; CARBON IONS; DOSE-RESPONSE RELATIONSHIPS; GAMMA RADIATION; INACTIVATION; ION BEAMS; IRRADIATION; LET; NITROGEN IONS; OXYGEN IONS; RADIATION DOSES; RBE; SURVIVAL CURVES; ATOMIC IONS; BACILLUS; BACTERIA; BEAMS; BIOLOGICAL EFFECTS; CHARGED PARTICLES; DOSES; ELECTROMAGNETIC RADIATION; ENERGY TRANSFER; IONIZING RADIATIONS; IONS; MICROORGANISMS; RADIATION EFFECTS; RADIATIONS; SPORES; 560131* - Radiation Effects on Microorganisms- Basic Studies- (-1987)
OSTI ID:
7358342
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JRARA
Submitting Site:
INIS
Size:
Pages: 99-112
Announcement Date:
Jul 01, 1976

Citation Formats

Yatagai, F, Takahashi, T, and Matsuyama, A. Inactivation of bacterial cells by cyclotron beams. Japan: N. p., 1975. Web.
Yatagai, F, Takahashi, T, & Matsuyama, A. Inactivation of bacterial cells by cyclotron beams. Japan.
Yatagai, F, Takahashi, T, and Matsuyama, A. 1975. "Inactivation of bacterial cells by cyclotron beams." Japan.
@misc{etde_7358342,
title = {Inactivation of bacterial cells by cyclotron beams}
author = {Yatagai, F, Takahashi, T, and Matsuyama, A}
abstractNote = {B. subtilis spores, E. coli Bsub(s-1) and E. coli B/r were bombarded with ..cap alpha..-particles and heavy ions of carbon, nitrogen and oxygen accelerated in the IPCR Cyclotron. The RBE versus LETsub(infinity) curve for B. subtilis spores showed a maximum peak at 120 keV/..mu..m, while those for E. coli Bsub(s-1) and E. coli B/r declined without any maximum as LETsub(infinity) values increased. In the region of ..cap alpha..-particles, the effective inactivation cross section (Ssub(eff)) for these three strains increased with increasing LETsub(infinity), and the rates of increase in Ssub(eff) in the LET region from --30 to --150 keV/..mu..m were 15.0, 1.5 and 2.5 times for B. subtilis spores, E. coli Bsub(s-1) and E. coli B/r, respectively. In the case of B. subtilis spores, Ssub(eff) values for heavy ions were almost independent of their energies, but the other two strains showed a considerable dependence upon beam energy. The characteristic LET dependence of Ssub(eff) observed in this study was fairly well explained by the target theory based on microdose concept.}
journal = []
volume = {16:2}
journal type = {AC}
place = {Japan}
year = {1975}
month = {Jun}
}