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The behavior of the vascular system in the experimental tumor radiotherapy

Abstract

The rat ascites hepatoma AH109A transplanted and grown in the rat transparent chamber developed a tumor specific vascular system, the process of which was quantitatively studied because of the vascular length, surface area, and volume per mm/sup 3/ of tissue. The values changed characteristically in each stage of the course. The tumor was irradiated in a chamber with 3000 R of /sup 60/Co ..gamma..-rays, and the tumor cells died leaving behind highly dense capillary networks, which gradually returned to normal level by 7 days after irradiation. The blood vessels, either preformed or newly formed, in the control tissue without tumor were not damaged by this dose. But the proliferation of capillary buds were inhibited slightly with 400 R and completely with 4000 R.
Authors:
Yamaura, H; Matsuzawa, T; Sato, H; [1]  Ito, Yasuhiko
  1. Tohoku Univ., Sendai (Japan). Research Inst. for Tuberculosis, Leprosy and Cancer
Publication Date:
Jul 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-244390; EDB-76-077008
Resource Relation:
Journal Name: Gan No Rinsho; (Japan); Journal Volume: 21:9
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; CAPILLARIES; BIOLOGICAL RADIATION EFFECTS; EHRLICH ASCITES TUMOR; GAMMA RADIATION; LOCAL IRRADIATION; MORPHOLOGICAL CHANGES; RADIOTHERAPY; RATS; TIME DEPENDENCE; ANIMALS; BIOLOGICAL EFFECTS; BLOOD VESSELS; CARDIOVASCULAR SYSTEM; DISEASES; ELECTROMAGNETIC RADIATION; EXPERIMENTAL NEOPLASMS; IONIZING RADIATIONS; IRRADIATION; MAMMALS; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; RADIATION EFFECTS; RADIATIONS; RADIOLOGY; RODENTS; THERAPY; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
7358282
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: GANRA
Submitting Site:
INIS
Size:
Pages: 702-706
Announcement Date:
Jul 01, 1976

Citation Formats

Yamaura, H, Matsuzawa, T, Sato, H, and Ito, Yasuhiko. The behavior of the vascular system in the experimental tumor radiotherapy. Japan: N. p., 1975. Web.
Yamaura, H, Matsuzawa, T, Sato, H, & Ito, Yasuhiko. The behavior of the vascular system in the experimental tumor radiotherapy. Japan.
Yamaura, H, Matsuzawa, T, Sato, H, and Ito, Yasuhiko. 1975. "The behavior of the vascular system in the experimental tumor radiotherapy." Japan.
@misc{etde_7358282,
title = {The behavior of the vascular system in the experimental tumor radiotherapy}
author = {Yamaura, H, Matsuzawa, T, Sato, H, and Ito, Yasuhiko}
abstractNote = {The rat ascites hepatoma AH109A transplanted and grown in the rat transparent chamber developed a tumor specific vascular system, the process of which was quantitatively studied because of the vascular length, surface area, and volume per mm/sup 3/ of tissue. The values changed characteristically in each stage of the course. The tumor was irradiated in a chamber with 3000 R of /sup 60/Co ..gamma..-rays, and the tumor cells died leaving behind highly dense capillary networks, which gradually returned to normal level by 7 days after irradiation. The blood vessels, either preformed or newly formed, in the control tissue without tumor were not damaged by this dose. But the proliferation of capillary buds were inhibited slightly with 400 R and completely with 4000 R.}
journal = []
volume = {21:9}
journal type = {AC}
place = {Japan}
year = {1975}
month = {Jul}
}