You need JavaScript to view this

Investigations of DNA-repair in New Zealand mice

Technical Report:

Abstract

DNA repair was investigated in New Zealand mice strains which developed murine lupus and compared with Swiss control mice. Unscheduled DNA synthesis demonstrated by autoradiography was used to measure the repair capacity of spleen cells. After gamma-irradiation DNA repair was decreased in the autoimmune strains, while it was significantly increased after UV-irradiation. A possible relationship between repair capacity after gamma-respectively UV-irradiation and the etiologic factor of autoimmunity is discussed. (auth)
Publication Date:
Sep 01, 1974
Product Type:
Technical Report
Report Number:
SGAE-2334; BL-107/74
Reference Number:
EDB-76-038303
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; DNA; BIOLOGICAL REPAIR; GAMMA RADIATION; IRRADIATION; MICE; SPLEEN CELLS; ULTRAVIOLET RADIATION; ANIMAL CELLS; ANIMALS; BIOLOGICAL RECOVERY; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; MAMMALS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATIONS; RECOVERY; REPAIR; RODENTS; SOMATIC CELLS; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
7356693
Research Organizations:
Oesterreichische Studiengesellschaft fuer Atomenergie G.m.b.H., Vienna
Country of Origin:
Austria
Language:
German
Availability:
INIS
Submitting Site:
INIS
Size:
Pages: 15
Announcement Date:

Technical Report:

Citation Formats

Tuschl, H, Kovac, R, and Altmann, H. Investigations of DNA-repair in New Zealand mice. Austria: N. p., 1974. Web.
Tuschl, H, Kovac, R, & Altmann, H. Investigations of DNA-repair in New Zealand mice. Austria.
Tuschl, H, Kovac, R, and Altmann, H. 1974. "Investigations of DNA-repair in New Zealand mice." Austria.
@misc{etde_7356693,
title = {Investigations of DNA-repair in New Zealand mice}
author = {Tuschl, H, Kovac, R, and Altmann, H}
abstractNote = {DNA repair was investigated in New Zealand mice strains which developed murine lupus and compared with Swiss control mice. Unscheduled DNA synthesis demonstrated by autoradiography was used to measure the repair capacity of spleen cells. After gamma-irradiation DNA repair was decreased in the autoimmune strains, while it was significantly increased after UV-irradiation. A possible relationship between repair capacity after gamma-respectively UV-irradiation and the etiologic factor of autoimmunity is discussed. (auth)}
place = {Austria}
year = {1974}
month = {Sep}
}