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Use of pyrophosphate-/sup 99m/Tc in diagnosis of malignant tumors of bones

Abstract

Pyrophosphate-/sup 99m/Tc was administered intravenously in a dose of 0.05 to 0.08 mCi per 1 kg body weight of the patient. Studies were made after 4, 6, and 24 hours with fixed and movable detectors. During investigations a gamma-chamber magnetic memory and a 4096-channel analyzer were also used. A quantitative processing of the material was made. The authors determined distribution of the preparation in normal and pathological bone tissue. A total of 142 patients with tumors of the bone tissue were examined; 858 radioisotope measurements were made. An analysis of accumulation of pyrophosphate-/sup 99m/Tc in primary osteogenic tumors in systemic affections of the bones and bone metastases was made. There is a relation between the concentration of the radiopharmaceutical preparation and the morphological structure of the tumor. Reduction in the accumulation of the radioactive indicator took place after radiation and medicinal effect, this made it possible to judge the regression of the tumor.
Publication Date:
Oct 01, 1976
Product Type:
Journal Article
Reference Number:
EDB-77-003751
Resource Relation:
Journal Name: Med. Radiol.; (USSR); Journal Volume: 21:10
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BONE TISSUES; NEOPLASMS; DIAGNOSIS; SCINTISCANNING; TECHNETIUM 99; ISOMERIC NUCLEI; PATIENTS; PYROPHOSPHATES; RADIOPHARMACEUTICALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CONNECTIVE TISSUE; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; NUCLEI; ODD-EVEN NUCLEI; OXYGEN COMPOUNDS; PHOSPHORUS COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; TISSUES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7349181
Research Organizations:
Scientific-Research Inst. of Oncology, Moscow
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: MERAA
Submitting Site:
TIC
Size:
Pages: 59-65
Announcement Date:
Dec 01, 1976

Citation Formats

Kasatkin, Yu N, Purizhanskii, I I, Survila, Z P, Agranat, V Z, and Korsunskii, V N. Use of pyrophosphate-/sup 99m/Tc in diagnosis of malignant tumors of bones. USSR: N. p., 1976. Web.
Kasatkin, Yu N, Purizhanskii, I I, Survila, Z P, Agranat, V Z, & Korsunskii, V N. Use of pyrophosphate-/sup 99m/Tc in diagnosis of malignant tumors of bones. USSR.
Kasatkin, Yu N, Purizhanskii, I I, Survila, Z P, Agranat, V Z, and Korsunskii, V N. 1976. "Use of pyrophosphate-/sup 99m/Tc in diagnosis of malignant tumors of bones." USSR.
@misc{etde_7349181,
title = {Use of pyrophosphate-/sup 99m/Tc in diagnosis of malignant tumors of bones}
author = {Kasatkin, Yu N, Purizhanskii, I I, Survila, Z P, Agranat, V Z, and Korsunskii, V N}
abstractNote = {Pyrophosphate-/sup 99m/Tc was administered intravenously in a dose of 0.05 to 0.08 mCi per 1 kg body weight of the patient. Studies were made after 4, 6, and 24 hours with fixed and movable detectors. During investigations a gamma-chamber magnetic memory and a 4096-channel analyzer were also used. A quantitative processing of the material was made. The authors determined distribution of the preparation in normal and pathological bone tissue. A total of 142 patients with tumors of the bone tissue were examined; 858 radioisotope measurements were made. An analysis of accumulation of pyrophosphate-/sup 99m/Tc in primary osteogenic tumors in systemic affections of the bones and bone metastases was made. There is a relation between the concentration of the radiopharmaceutical preparation and the morphological structure of the tumor. Reduction in the accumulation of the radioactive indicator took place after radiation and medicinal effect, this made it possible to judge the regression of the tumor.}
journal = []
volume = {21:10}
journal type = {AC}
place = {USSR}
year = {1976}
month = {Oct}
}