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The diagnosis of the gastric cancer using catheter-type semiconductor radiation detector. Comparison of diagnostic values of. beta. -emitting radionuclide label with. gamma. -emitting label

Journal Article:

Abstract

The diagnostic usefulness of /sup 32/P-phosphate for human gastric cancer, using a catheter-type semiconductor radiation detector (CASRAD) combined with gastrofiberscope technique, has already been reported by the authors. They have in addition used sup(99m)Tc-bleomycin, sup(99m)Tc-tetracycline in the diagnosis of experimental rabbit gastric cancer, too. In the present study, further refinement of the technique for the ..beta..-ray labeled substance (/sup 32/P-phosphate) for detection of the gastric cancer was compared with that of ..gamma..-ray labeled substance (sup(99m)Tc-tetracycline). A more correct diagnosis of the gastric cancer by in vivo measurement of beta activity could be obtained, when the collimater, made of stainless steel, was attached to the top of the detector. In this way contribution to the count from the adjacent tissues or organs could be eliminated. They were unable to produce an effective and useful collimater for ..gamma..-ray labeled substance which could to be used safely in vivo. Because of the unsatisfactory collimater, radioactivities of the adjacent organs caused on increase in the radioactivity of the background. Therefore inspite of the recent introduction of various sup(99m)Tc-tumor agents, these labels were not applicable to the CASRAD method. For such a small detector system, ..beta..-labels, represented by /sup 32/P-phosphate, was still prefererable to ..gamma..-labels.
Authors:
Sassa, R; Iwase, T; [1]  Sugita, T; Iio, M
  1. Asahi Life Foundation, Tokyo (Japan). Inst. for Adult Diseases
Publication Date:
Jun 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-248695; EDB-76-076752
Resource Relation:
Journal Name: Kaku Igaku; (Japan); Journal Volume: 12:3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; DIAGNOSTIC TECHNIQUES; COLLIMATORS; DIAGNOSIS; IN VIVO; LIVER; NEOPLASMS; PHOSPHORUS 32; RABBITS; RADIOPHARMACEUTICALS; SEMICONDUCTOR DETECTORS; STOMACH; TECHNETIUM 99; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; DAYS LIVING RADIOISOTOPES; DIGESTIVE SYSTEM; DISEASES; DRUGS; GASTROINTESTINAL TRACT; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MAMMALS; MEASURING INSTRUMENTS; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; ORGANS; PHOSPHORUS ISOTOPES; RADIATION DETECTORS; RADIOACTIVE MATERIALS; RADIOISOTOPES; TECHNETIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7345067
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: KAIGB
Submitting Site:
INIS
Size:
Pages: 255-260
Announcement Date:
Jul 01, 1976

Journal Article:

Citation Formats

Sassa, R, Iwase, T, Sugita, T, and Iio, M. The diagnosis of the gastric cancer using catheter-type semiconductor radiation detector. Comparison of diagnostic values of. beta. -emitting radionuclide label with. gamma. -emitting label. Japan: N. p., 1975. Web.
Sassa, R, Iwase, T, Sugita, T, & Iio, M. The diagnosis of the gastric cancer using catheter-type semiconductor radiation detector. Comparison of diagnostic values of. beta. -emitting radionuclide label with. gamma. -emitting label. Japan.
Sassa, R, Iwase, T, Sugita, T, and Iio, M. 1975. "The diagnosis of the gastric cancer using catheter-type semiconductor radiation detector. Comparison of diagnostic values of. beta. -emitting radionuclide label with. gamma. -emitting label." Japan.
@misc{etde_7345067,
title = {The diagnosis of the gastric cancer using catheter-type semiconductor radiation detector. Comparison of diagnostic values of. beta. -emitting radionuclide label with. gamma. -emitting label}
author = {Sassa, R, Iwase, T, Sugita, T, and Iio, M}
abstractNote = {The diagnostic usefulness of /sup 32/P-phosphate for human gastric cancer, using a catheter-type semiconductor radiation detector (CASRAD) combined with gastrofiberscope technique, has already been reported by the authors. They have in addition used sup(99m)Tc-bleomycin, sup(99m)Tc-tetracycline in the diagnosis of experimental rabbit gastric cancer, too. In the present study, further refinement of the technique for the ..beta..-ray labeled substance (/sup 32/P-phosphate) for detection of the gastric cancer was compared with that of ..gamma..-ray labeled substance (sup(99m)Tc-tetracycline). A more correct diagnosis of the gastric cancer by in vivo measurement of beta activity could be obtained, when the collimater, made of stainless steel, was attached to the top of the detector. In this way contribution to the count from the adjacent tissues or organs could be eliminated. They were unable to produce an effective and useful collimater for ..gamma..-ray labeled substance which could to be used safely in vivo. Because of the unsatisfactory collimater, radioactivities of the adjacent organs caused on increase in the radioactivity of the background. Therefore inspite of the recent introduction of various sup(99m)Tc-tumor agents, these labels were not applicable to the CASRAD method. For such a small detector system, ..beta..-labels, represented by /sup 32/P-phosphate, was still prefererable to ..gamma..-labels.}
journal = {Kaku Igaku; (Japan)}
volume = {12:3}
journal type = {AC}
place = {Japan}
year = {1975}
month = {Jun}
}