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Regulation of glycogenesis in bone marrow of irradiated body

Abstract

In connection with a stimulating effect of insulin on postradiation restoration of medullary hemopoiesis the authors studied the influence of insulin on glycogenesis of bone marrow in comparison with glycogenesis of the liver under the conditions of irradiation. As a result the experiment made on white mice the authors established that the level of glycogen in both tissues on the first two days after irradiation (750 R) increased. Later, the decrease of glycogen concentration was observed and its exhaustion was more marked. Insulin protected bone marrow and the liver from exhaustion of glycogen reserves and ensured a higher level of glycogen in the liver. It is supposed that the regulation mechanisms by means of insulin of glycogenesis in the bone marrow and the liver are mainly of the same type. The influence of insulin on carbohydrate metabolism in the bone marrow is likely to be of significance for postradiation hemopoiesis.
Authors:
Publication Date:
Feb 01, 1976
Product Type:
Journal Article
Reference Number:
EDB-76-088452
Resource Relation:
Journal Name: Med. Radiol.; (USSR); Journal Volume: 21:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BONE MARROW; GLYCOGEN; BIOLOGICAL RADIATION EFFECTS; BIOSYNTHESIS; INSULIN; BIOLOGICAL EFFECTS; LIVER; BLOOD FORMATION; METABOLISM; MICE; ANIMALS; BODY; CARBOHYDRATES; DIGESTIVE SYSTEM; GLANDS; HEMATOPOIETIC SYSTEM; HORMONES; MAMMALS; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HORMONES; POLYSACCHARIDES; RADIATION EFFECTS; RODENTS; SACCHARIDES; SYNTHESIS; TISSUES; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
7341181
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: MERAA
Submitting Site:
TIC
Size:
Pages: 49-53
Announcement Date:
Sep 01, 1976

Citation Formats

Barkalaya, A I. Regulation of glycogenesis in bone marrow of irradiated body. USSR: N. p., 1976. Web.
Barkalaya, A I. Regulation of glycogenesis in bone marrow of irradiated body. USSR.
Barkalaya, A I. 1976. "Regulation of glycogenesis in bone marrow of irradiated body." USSR.
@misc{etde_7341181,
title = {Regulation of glycogenesis in bone marrow of irradiated body}
author = {Barkalaya, A I}
abstractNote = {In connection with a stimulating effect of insulin on postradiation restoration of medullary hemopoiesis the authors studied the influence of insulin on glycogenesis of bone marrow in comparison with glycogenesis of the liver under the conditions of irradiation. As a result the experiment made on white mice the authors established that the level of glycogen in both tissues on the first two days after irradiation (750 R) increased. Later, the decrease of glycogen concentration was observed and its exhaustion was more marked. Insulin protected bone marrow and the liver from exhaustion of glycogen reserves and ensured a higher level of glycogen in the liver. It is supposed that the regulation mechanisms by means of insulin of glycogenesis in the bone marrow and the liver are mainly of the same type. The influence of insulin on carbohydrate metabolism in the bone marrow is likely to be of significance for postradiation hemopoiesis.}
journal = []
volume = {21:2}
journal type = {AC}
place = {USSR}
year = {1976}
month = {Feb}
}