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Intermittent hyperthyreosis. A heat stress syndrome

Journal Article:

Abstract

Intermittent hyperthyreosis occurs under various forms of stress, especially heat stress. The clinician may diagnose such cases as masked or apathetic hyperthyroidism or 'forme fruste' hyperthyreosis or thyroid autonomy. As most routine and standard tests may here yield inconsistent results, it is the patients' anamnesis which may provide the clue. Our Bioclimatology Unit has now seen over 100 cases in which thyroid hypersensitivity towards heat was the most prominent syndrome: 10-15% of weather-sensitive patients are affected. The patients complain before or during heat spells of such contradictory symptoms as insomnia, irritability, tension, tachycardia, palpitations, precordial pain, dyspnoe, flushes with sweating or chills, tremor, abdominal pain or diarrhea, polyuria or pollakisuria, weight loss in spite of ravenous appetite, fatigue, exhaustion, depression, adynamia, lack of concentration and confusion. Determination of urinary neurohormones allows a differential diagnosis, intermittent hyperthyreosis being characterized by three cardinal symptoms: tachycardia - every case with more than 80 pulse beats being suspect (not specific); urinary histamine - every case excreting more than 90 ..mu..g/day being suspect. Again the drawback of this test is its lack of specificity, as histamine may also be increased in cases of allergy and spondylitis; urinary thyroxine - every case excreting more than 20  More>>
Authors:
Sulman, F G; Tal, E; Pfeifer, Y; Superstine, E [1] 
  1. Hebrew Univ., Jerusalem (Israel). Dept. of Applied Pharmacology
Publication Date:
Sep 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-242371; EDB-76-093585
Resource Relation:
Journal Name: Horm. Metab. Res.; (Germany, Federal Republic of); Journal Volume: 7:5; Other Information: 1 fig.; 2 tabs.; 18 refs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; HYPERTHYROIDISM; ADRENALINE; ANTITHYROID DRUGS; EXCRETION; IODINE 125; NORADRENALINE; NUCLEAR MEDICINE; PATIENTS; RADIOIMMUNOASSAY; SEROTONIN; THYROID; THYROXINE; URINE; ADRENAL HORMONES; AMINES; AMINO ACIDS; AZOLES; BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BIOLOGICAL WASTES; BODY; BODY FLUIDS; CARBOXYLIC ACIDS; CLEARANCE; DAYS LIVING RADIOISOTOPES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; ENDOCRINE DISEASES; ENDOCRINE GLANDS; GLANDS; HETEROCYCLIC COMPOUNDS; HORMONES; HYDROXY COMPOUNDS; INDOLES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PEPTIDE HORMONES; PYRROLES; RADIOASSAY; RADIOISOTOPES; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; STEROID HORMONES; SYMPATHOMIMETICS; THYROID HORMONES; TRACER TECHNIQUES; TRYPTAMINES; WASTES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7339220
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: HMMRA
Submitting Site:
INIS
Size:
Pages: 424-428
Announcement Date:

Journal Article:

Citation Formats

Sulman, F G, Tal, E, Pfeifer, Y, and Superstine, E. Intermittent hyperthyreosis. A heat stress syndrome. Germany: N. p., 1975. Web.
Sulman, F G, Tal, E, Pfeifer, Y, & Superstine, E. Intermittent hyperthyreosis. A heat stress syndrome. Germany.
Sulman, F G, Tal, E, Pfeifer, Y, and Superstine, E. 1975. "Intermittent hyperthyreosis. A heat stress syndrome." Germany.
@misc{etde_7339220,
title = {Intermittent hyperthyreosis. A heat stress syndrome}
author = {Sulman, F G, Tal, E, Pfeifer, Y, and Superstine, E}
abstractNote = {Intermittent hyperthyreosis occurs under various forms of stress, especially heat stress. The clinician may diagnose such cases as masked or apathetic hyperthyroidism or 'forme fruste' hyperthyreosis or thyroid autonomy. As most routine and standard tests may here yield inconsistent results, it is the patients' anamnesis which may provide the clue. Our Bioclimatology Unit has now seen over 100 cases in which thyroid hypersensitivity towards heat was the most prominent syndrome: 10-15% of weather-sensitive patients are affected. The patients complain before or during heat spells of such contradictory symptoms as insomnia, irritability, tension, tachycardia, palpitations, precordial pain, dyspnoe, flushes with sweating or chills, tremor, abdominal pain or diarrhea, polyuria or pollakisuria, weight loss in spite of ravenous appetite, fatigue, exhaustion, depression, adynamia, lack of concentration and confusion. Determination of urinary neurohormones allows a differential diagnosis, intermittent hyperthyreosis being characterized by three cardinal symptoms: tachycardia - every case with more than 80 pulse beats being suspect (not specific); urinary histamine - every case excreting more than 90 ..mu..g/day being suspect. Again the drawback of this test is its lack of specificity, as histamine may also be increased in cases of allergy and spondylitis; urinary thyroxine - every case excreting more than 20 ..mu..g/day T-4 being suspect. This is the only specific test. Therapy should make use of lithium carbonate and betablockers. Propyl thiouracil is rarely required.}
journal = {Horm. Metab. Res.; (Germany, Federal Republic of)}
volume = {7:5}
journal type = {AC}
place = {Germany}
year = {1975}
month = {Sep}
}