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Testicular function after radiotherapy to inverted 'Y' field for malignant lymphoma

Journal Article:

Abstract

Testicular function was estimated by sperm counts, hormone assays and recording of reported conceptions in 9 patients irradiated for malignant lymphoma. The treatment had been an inverted 'Y' field including the inguinal regions with, in addition, a mantle field in 8 patients. Azoospermia or severe oligozoospermia was found in all but 1 patient, and the FSH levels were uniformly elevated. Testosterone and LH were within normal limits except in 2 patients with slightly subnormal testosterone levels. 7 of the patients were married to women of fertile age, and in 3 cases the wife became pregnant and gave birth to a healthy child. The time lapses from irradiation to conception were 18, 40 and 57 months. 2 of these patients had severe oligozoospermia on examination 2 and 4 months respectively from conception. Thus fertility may possibly be underestimated by sperm counting and hormone assays after this type of radiotherapy.
Authors:
Asbjoernsen, G; Molne, K; Klepp, O; Aakvaag, A; [1]  Rikshospitalet, Oslo (Norway))
  1. Norske Radiumhospital, Oslo
Publication Date:
Jan 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-08-281262; EDB-77-038722
Resource Relation:
Journal Name: Scand. J. Haematol.; (Denmark); Journal Volume: 17
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; RADIOTHERAPY; SIDE EFFECTS; TESTES; BIOLOGICAL RADIATION EFFECTS; FSH; LOCAL IRRADIATION; LYMPHOMAS; MAN; ANIMALS; BIOLOGICAL EFFECTS; BODY; DISEASES; GONADOTROPINS; GONADS; HORMONES; IRRADIATION; MALE GENITALS; MAMMALS; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; PEPTIDE HORMONES; PITUITARY HORMONES; PRIMATES; RADIATION EFFECTS; RADIOLOGY; THERAPY; VERTEBRATES; 560151* - Radiation Effects on Animals- Man
OSTI ID:
7336178
Country of Origin:
Denmark
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: SJHAA
Submitting Site:
INIS
Size:
Pages: 96-100
Announcement Date:

Journal Article:

Citation Formats

Asbjoernsen, G, Molne, K, Klepp, O, Aakvaag, A, and Rikshospitalet, Oslo (Norway)). Testicular function after radiotherapy to inverted 'Y' field for malignant lymphoma. Denmark: N. p., 1976. Web.
Asbjoernsen, G, Molne, K, Klepp, O, Aakvaag, A, & Rikshospitalet, Oslo (Norway)). Testicular function after radiotherapy to inverted 'Y' field for malignant lymphoma. Denmark.
Asbjoernsen, G, Molne, K, Klepp, O, Aakvaag, A, and Rikshospitalet, Oslo (Norway)). 1976. "Testicular function after radiotherapy to inverted 'Y' field for malignant lymphoma." Denmark.
@misc{etde_7336178,
title = {Testicular function after radiotherapy to inverted 'Y' field for malignant lymphoma}
author = {Asbjoernsen, G, Molne, K, Klepp, O, Aakvaag, A, and Rikshospitalet, Oslo (Norway))}
abstractNote = {Testicular function was estimated by sperm counts, hormone assays and recording of reported conceptions in 9 patients irradiated for malignant lymphoma. The treatment had been an inverted 'Y' field including the inguinal regions with, in addition, a mantle field in 8 patients. Azoospermia or severe oligozoospermia was found in all but 1 patient, and the FSH levels were uniformly elevated. Testosterone and LH were within normal limits except in 2 patients with slightly subnormal testosterone levels. 7 of the patients were married to women of fertile age, and in 3 cases the wife became pregnant and gave birth to a healthy child. The time lapses from irradiation to conception were 18, 40 and 57 months. 2 of these patients had severe oligozoospermia on examination 2 and 4 months respectively from conception. Thus fertility may possibly be underestimated by sperm counting and hormone assays after this type of radiotherapy.}
journal = {Scand. J. Haematol.; (Denmark)}
volume = {17}
journal type = {AC}
place = {Denmark}
year = {1976}
month = {Jan}
}