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DNA synthesis and uv resistance in Escherichia coli K12 cells

Journal Article:

Abstract

The influence was studied of preirradiation inhibition of proteosynthesis by amino acids starvation on survival and DNA synthesis in E. coli K 12 cells, which differ by their genetic features with regard to a certain type of repair. The surviving fraction was studied by appropriate dilution of cell suspension and spreading on agar plates. DNA synthesis was investigated by the incorporation of thymine-2-/sup 14/C. In our conditions a correlation was found between cell survival and the resistance of DNA replication to UV radiation in cells proficient in excision and post-replication repair. This correlation was not found in the excision deficient strain. It is concluded that enhanced resistance of DNA replication is not a sufficient condition for enhanced cell resistance.
Authors:
Slezarikova, V [1] 
  1. Slovenska Akademia Vied, Bratislava (Czechoslovakia). Vyskumny Ustav Onkologicky
Publication Date:
Jan 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-08-286716; EDB-77-045327
Resource Relation:
Journal Name: Biologia (Bratislava); (Czechoslovakia); Journal Volume: 31:6
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; DNA; BIOSYNTHESIS; ESCHERICHIA COLI; SURVIVAL CURVES; AMINO ACIDS; BIOLOGICAL REPAIR; CARBON 14 COMPOUNDS; CHLORAMPHENICOL; DNA REPLICATION; FASTING; LABELLED COMPOUNDS; RADIOSENSITIVITY; THYMINE; TRACER TECHNIQUES; ULTRAVIOLET RADIATION; ANTIBIOTICS; AZINES; BACTERIA; BIOLOGICAL RECOVERY; CARBOXYLIC ACIDS; DRUGS; ELECTROMAGNETIC RADIATION; HETEROCYCLIC COMPOUNDS; HYDROXY COMPOUNDS; ISOTOPE APPLICATIONS; MICROORGANISMS; NUCLEIC ACID REPLICATION; NUCLEIC ACIDS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PYRIMIDINES; RADIATIONS; RECOVERY; REPAIR; SYNTHESIS; URACILS; 560131* - Radiation Effects on Microorganisms- Basic Studies- (-1987)
OSTI ID:
7334001
Country of Origin:
Serbia and Montenegro
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: BLOAA
Submitting Site:
INIS
Size:
Pages: 393-400
Announcement Date:

Journal Article:

Citation Formats

Slezarikova, V. DNA synthesis and uv resistance in Escherichia coli K12 cells. Serbia and Montenegro: N. p., 1976. Web.
Slezarikova, V. DNA synthesis and uv resistance in Escherichia coli K12 cells. Serbia and Montenegro.
Slezarikova, V. 1976. "DNA synthesis and uv resistance in Escherichia coli K12 cells." Serbia and Montenegro.
@misc{etde_7334001,
title = {DNA synthesis and uv resistance in Escherichia coli K12 cells}
author = {Slezarikova, V}
abstractNote = {The influence was studied of preirradiation inhibition of proteosynthesis by amino acids starvation on survival and DNA synthesis in E. coli K 12 cells, which differ by their genetic features with regard to a certain type of repair. The surviving fraction was studied by appropriate dilution of cell suspension and spreading on agar plates. DNA synthesis was investigated by the incorporation of thymine-2-/sup 14/C. In our conditions a correlation was found between cell survival and the resistance of DNA replication to UV radiation in cells proficient in excision and post-replication repair. This correlation was not found in the excision deficient strain. It is concluded that enhanced resistance of DNA replication is not a sufficient condition for enhanced cell resistance.}
journal = {Biologia (Bratislava); (Czechoslovakia)}
volume = {31:6}
journal type = {AC}
place = {Serbia and Montenegro}
year = {1976}
month = {Jan}
}