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Effects of ionizing radiations and of metabolic inhibitors on the synthesis of RNA in lymphocites bred in culture

Abstract

Studies are conducted of the activation kinetics of the RNA synthesis and of proteins, during their blasto transformation stage of human circulating lymphocytes in culture breeding and of the effects caused by some metabolic inhibitors and by ionizing radiations on RNA synthesis. The results obtained lead to assume that the initial activation concern RNA nuclear linkages with fast turnover and scarce sensibility to actinomycin and that the exposure to ionizing radiations causes a significant reduction of the RNA synthesis rate at the initial phases of the activation process while it hasn't any effect on the later stage.
Authors:
Farulla, A; Alimena, G; Castagna, R; Naro, G; Percoco, V D [1] 
  1. Rome Univ. (Italy)
Publication Date:
Jan 01, 1954
Product Type:
Journal Article
Reference Number:
AIX-07-265477; EDB-77-014475
Resource Relation:
Journal Name: Securitas; (Italy); Journal Volume: 59:5-6
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; LYMPHOCYTES; BIOLOGICAL RADIATION EFFECTS; RNA; BIOSYNTHESIS; CULTURE MEDIA; METABOLISM; ANIMAL CELLS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; LEUKOCYTES; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATION EFFECTS; SOMATIC CELLS; SYNTHESIS; 560121* - Radiation Effects on Cells- External Source- (-1987)
OSTI ID:
7332377
Country of Origin:
Italy
Language:
Italian
Other Identifying Numbers:
Journal ID: CODEN: SECTA
Submitting Site:
INIS
Size:
Pages: 299-308
Announcement Date:
Nov 01, 1976

Citation Formats

Farulla, A, Alimena, G, Castagna, R, Naro, G, and Percoco, V D. Effects of ionizing radiations and of metabolic inhibitors on the synthesis of RNA in lymphocites bred in culture. Italy: N. p., 1954. Web.
Farulla, A, Alimena, G, Castagna, R, Naro, G, & Percoco, V D. Effects of ionizing radiations and of metabolic inhibitors on the synthesis of RNA in lymphocites bred in culture. Italy.
Farulla, A, Alimena, G, Castagna, R, Naro, G, and Percoco, V D. 1954. "Effects of ionizing radiations and of metabolic inhibitors on the synthesis of RNA in lymphocites bred in culture." Italy.
@misc{etde_7332377,
title = {Effects of ionizing radiations and of metabolic inhibitors on the synthesis of RNA in lymphocites bred in culture}
author = {Farulla, A, Alimena, G, Castagna, R, Naro, G, and Percoco, V D}
abstractNote = {Studies are conducted of the activation kinetics of the RNA synthesis and of proteins, during their blasto transformation stage of human circulating lymphocytes in culture breeding and of the effects caused by some metabolic inhibitors and by ionizing radiations on RNA synthesis. The results obtained lead to assume that the initial activation concern RNA nuclear linkages with fast turnover and scarce sensibility to actinomycin and that the exposure to ionizing radiations causes a significant reduction of the RNA synthesis rate at the initial phases of the activation process while it hasn't any effect on the later stage.}
journal = []
volume = {59:5-6}
journal type = {AC}
place = {Italy}
year = {1954}
month = {Jan}
}