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Cancers other than leukemia

Journal Article:

Abstract

Cancers which are unlikely to appear among atomic bomb survirors in excess of natural incidence include skin cancer and bone cancer, as these appear to require for their initiation doses that are incompatible with life if administered on a whole body basis. Although chronic lymphocytic leukemia continues to provide an important exception, and for many sites of cancer there is not yet evidence that radiation has increased incidence above normal levels, the data on A-bomb survivors are otherwise consistent with the hypothesis that the carcinogenic effect of ionizing radiation is general, involving all tissues. Studies of cancer among A-bomb survivors are notably limited with respect to the influence of variables other than dose, age, sex, and time. It seems highly desirable that other risk factors be studied in conjunction with radiation dose and demographic variables in an effort to detect interactions that might provide clues as to the etiology of cancer and as to the mechanisms by which ionizing radiation produces cancer. Provisional estimates suggest that the absolute risk of cancer, in terms of excess cases per 10/sup 6/ person-year rads (T65 dose) are about 1.6 for leukemia, 1.2 for thyroid, 2.1 for breast and 2.0 for lung, when estimation  More>>
Authors:
Beebe, G W; Kato, H [1] 
  1. Radiation Effects Research Foundation, Hiroshima (Japan)
Publication Date:
Sep 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-273017; EDB-77-027277
Resource Relation:
Journal Name: J. Radiat. Res.; (Japan); Journal Volume: 16:suppl.
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; DELAYED RADIATION EFFECTS; CARCINOMAS; DOSE-RESPONSE RELATIONSHIPS; LEUKEMIA; LEUKEMOGENESIS; LUNGS; MAMMARY GLANDS; MORTALITY; RADIATION DOSES; THYROID; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CARCINOGENESIS; DISEASES; DOSES; ENDOCRINE GLANDS; GLANDS; HEMIC DISEASES; NEOPLASMS; ORGANS; PATHOGENESIS; RADIATION EFFECTS; RESPIRATORY SYSTEM; 560151* - Radiation Effects on Animals- Man
OSTI ID:
7328071
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JRARA
Submitting Site:
INIS
Size:
Pages: 97-107
Announcement Date:
Dec 01, 1976

Journal Article:

Citation Formats

Beebe, G W, and Kato, H. Cancers other than leukemia. Japan: N. p., 1975. Web.
Beebe, G W, & Kato, H. Cancers other than leukemia. Japan.
Beebe, G W, and Kato, H. 1975. "Cancers other than leukemia." Japan.
@misc{etde_7328071,
title = {Cancers other than leukemia}
author = {Beebe, G W, and Kato, H}
abstractNote = {Cancers which are unlikely to appear among atomic bomb survirors in excess of natural incidence include skin cancer and bone cancer, as these appear to require for their initiation doses that are incompatible with life if administered on a whole body basis. Although chronic lymphocytic leukemia continues to provide an important exception, and for many sites of cancer there is not yet evidence that radiation has increased incidence above normal levels, the data on A-bomb survivors are otherwise consistent with the hypothesis that the carcinogenic effect of ionizing radiation is general, involving all tissues. Studies of cancer among A-bomb survivors are notably limited with respect to the influence of variables other than dose, age, sex, and time. It seems highly desirable that other risk factors be studied in conjunction with radiation dose and demographic variables in an effort to detect interactions that might provide clues as to the etiology of cancer and as to the mechanisms by which ionizing radiation produces cancer. Provisional estimates suggest that the absolute risk of cancer, in terms of excess cases per 10/sup 6/ person-year rads (T65 dose) are about 1.6 for leukemia, 1.2 for thyroid, 2.1 for breast and 2.0 for lung, when estimation is based on age-ATB groups that have demonstrated these effects.}
journal = {J. Radiat. Res.; (Japan)}
volume = {16:suppl.}
journal type = {AC}
place = {Japan}
year = {1975}
month = {Sep}
}