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Patient with pure red cell aplasia who was exposed to the atomic bomb near the site of blast

Journal Article:

Abstract

This paper describes a female patient who had been exposed at the age of 26 to the atomic bomb at a distance of 1.3 km from the bombed area. She was pointed out to have anemia and the disturbance of the liver in 1961. In 1963, she had iron deficiency, hypoleucocytosis, and hyper-..gamma.. globulinemia, and showed a high value of serum colloids. In 1969, she had more frequently anemia together with hyper ..gamma..-globulinemia. The erythrocyte sedimentation rate and serum colloids were still high. The positive reaction to the LE cells began to appear. The liver biopsy findings showed proliferation of Kupper cells in the lobule, decidual degeneration of some liver cells, infiltration of many round cells in the Glisson's sheath. Therefore, she was diagnosed as having pure red cell aplasia and lupoid hepatitis. However, in 1970 she was suspected of having pulmonary valvular insufficiency caused by pulmonary hypertension in spite of the continuous steroid therapy. In 1974, she died of jundice, hyper-..gamma..-globulinemia which accompanied urea in the blood and the increased values of nitrogen and NH/sub 3/. This patient was considered to be interested on the assumption of the relationships between exposure to the atomic bomb and disturbance of immunity.
Authors:
Toyoda, N; Matsukuma, G; Uchiyama, E; Tsunoo, S; Anpi, S [1] 
  1. Nagasaki Atomic Bomb Hospital (Japan)
Publication Date:
Mar 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-08-283678; EDB-77-038762
Resource Relation:
Journal Name: Hiroshima Igaku; (Japan); Journal Volume: 29:3
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; ANEMIAS; IMMUNITY; DELAYED RADIATION EFFECTS; HEPATITIS; HYPERTENSION; IMMUNOGLOBULINS; WOMEN; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; CARDIOVASCULAR DISEASES; DIGESTIVE SYSTEM DISEASES; DISEASES; FEMALES; GLOBULINS; HEMIC DISEASES; MAMMALS; MAN; ORGANIC COMPOUNDS; PRIMATES; PROTEINS; RADIATION EFFECTS; SYMPTOMS; VASCULAR DISEASES; VERTEBRATES; 560151* - Radiation Effects on Animals- Man
OSTI ID:
7324002
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: HIRGA
Submitting Site:
INIS
Size:
Pages: 249-255
Announcement Date:

Journal Article:

Citation Formats

Toyoda, N, Matsukuma, G, Uchiyama, E, Tsunoo, S, and Anpi, S. Patient with pure red cell aplasia who was exposed to the atomic bomb near the site of blast. Japan: N. p., 1976. Web.
Toyoda, N, Matsukuma, G, Uchiyama, E, Tsunoo, S, & Anpi, S. Patient with pure red cell aplasia who was exposed to the atomic bomb near the site of blast. Japan.
Toyoda, N, Matsukuma, G, Uchiyama, E, Tsunoo, S, and Anpi, S. 1976. "Patient with pure red cell aplasia who was exposed to the atomic bomb near the site of blast." Japan.
@misc{etde_7324002,
title = {Patient with pure red cell aplasia who was exposed to the atomic bomb near the site of blast}
author = {Toyoda, N, Matsukuma, G, Uchiyama, E, Tsunoo, S, and Anpi, S}
abstractNote = {This paper describes a female patient who had been exposed at the age of 26 to the atomic bomb at a distance of 1.3 km from the bombed area. She was pointed out to have anemia and the disturbance of the liver in 1961. In 1963, she had iron deficiency, hypoleucocytosis, and hyper-..gamma.. globulinemia, and showed a high value of serum colloids. In 1969, she had more frequently anemia together with hyper ..gamma..-globulinemia. The erythrocyte sedimentation rate and serum colloids were still high. The positive reaction to the LE cells began to appear. The liver biopsy findings showed proliferation of Kupper cells in the lobule, decidual degeneration of some liver cells, infiltration of many round cells in the Glisson's sheath. Therefore, she was diagnosed as having pure red cell aplasia and lupoid hepatitis. However, in 1970 she was suspected of having pulmonary valvular insufficiency caused by pulmonary hypertension in spite of the continuous steroid therapy. In 1974, she died of jundice, hyper-..gamma..-globulinemia which accompanied urea in the blood and the increased values of nitrogen and NH/sub 3/. This patient was considered to be interested on the assumption of the relationships between exposure to the atomic bomb and disturbance of immunity.}
journal = {Hiroshima Igaku; (Japan)}
volume = {29:3}
journal type = {AC}
place = {Japan}
year = {1976}
month = {Mar}
}