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Modification of the biologic dose to normal tissue by daily fraction

Abstract

A method to predict normal tissue injury is proposed that includes high daily doses and unusual times successfully by calculating a new value called BIR (Biologic Index of Reaction). BIR and NSD were calculated for various normal tissue reactions. With the aid of statistical correlation techniques it is found that the BIR model is better than the NSD model in predicting radiation myelopathy and vocal edema and as good as NSD IN PREDICTING RIB FRACTURE/ Neither model predicts pericardial effusion. In no case were the results of BIR inferior to those of NSD.
Authors:
Wollin, M; Kagan, A R [1] 
  1. Southern California Permanente Medical Group, Los Angeles Calif. (USA). Dep. of Radiation Therapy
Publication Date:
Dec 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-08-310391; EDB-77-134455
Resource Relation:
Journal Name: Acta Radiol., Ther., Phys., Biol.; (Sweden); Journal Volume: 15:6
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BIOLOGICAL RADIATION EFFECTS; MATHEMATICAL MODELS; RADIOTHERAPY; SIDE EFFECTS; FRACTIONATED IRRADIATION; MAN; RADIATION DOSES; TISSUES; ANIMALS; BIOLOGICAL EFFECTS; BODY; DOSES; IRRADIATION; MAMMALS; MEDICINE; NUCLEAR MEDICINE; PRIMATES; RADIATION EFFECTS; RADIOLOGY; THERAPY; VERTEBRATES; 560151* - Radiation Effects on Animals- Man
OSTI ID:
7319466
Country of Origin:
Sweden
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: ATHBA
Submitting Site:
INIS
Size:
Pages: 481-492
Announcement Date:
Jun 01, 1977

Citation Formats

Wollin, M, and Kagan, A R. Modification of the biologic dose to normal tissue by daily fraction. Sweden: N. p., 1976. Web.
Wollin, M, & Kagan, A R. Modification of the biologic dose to normal tissue by daily fraction. Sweden.
Wollin, M, and Kagan, A R. 1976. "Modification of the biologic dose to normal tissue by daily fraction." Sweden.
@misc{etde_7319466,
title = {Modification of the biologic dose to normal tissue by daily fraction}
author = {Wollin, M, and Kagan, A R}
abstractNote = {A method to predict normal tissue injury is proposed that includes high daily doses and unusual times successfully by calculating a new value called BIR (Biologic Index of Reaction). BIR and NSD were calculated for various normal tissue reactions. With the aid of statistical correlation techniques it is found that the BIR model is better than the NSD model in predicting radiation myelopathy and vocal edema and as good as NSD IN PREDICTING RIB FRACTURE/ Neither model predicts pericardial effusion. In no case were the results of BIR inferior to those of NSD.}
journal = []
volume = {15:6}
journal type = {AC}
place = {Sweden}
year = {1976}
month = {Dec}
}