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Radiolysis of aqueous solutions of insulin. [. gamma. rays]

Journal Article:

Abstract

The effect of ionizing radiation on diluted aqueous solutions of insulin is analyzed. The rate of decrease in its level (the loss of polarographic activity) is described by a first-order kinetic equation. The results lead to the concept of a direct effect on macromolecules in 'excited volumes'. The amount of inactivated molecules (i.e., the yield) in this volume is proportional to the solute concentration. In diluted aqueous solutions indirect radiation effects also take place. The paper evaluates these effects.
Authors:
Foitik, A; [1]  Kopoldova, J [2] 
  1. Ceskoslovenska Akademie Ved, Prague. Ustav Fyzikalni Chemie a Elektrochemie J. Heyrovskeho
  2. Ceskoslovenska Akademie Ved, Prague. Isotopova Laborator Biologickych Ustavu
Publication Date:
Aug 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-08-327666; EDB-77-141773
Resource Relation:
Journal Name: Collect. Czech. Chem. Commun.; (Czechoslovakia); Journal Volume: 41:8
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; INSULIN; RADIOLYSIS; AQUEOUS SOLUTIONS; CHEMICAL REACTION KINETICS; DOSE-RESPONSE RELATIONSHIPS; G VALUE; HYDROLYSIS; POLAROGRAPHY; QUANTITY RATIO; X RADIATION; CHEMICAL RADIATION EFFECTS; CHEMICAL REACTIONS; CHEMISTRY; DECOMPOSITION; DISPERSIONS; ELECTROMAGNETIC RADIATION; HORMONES; IONIZING RADIATIONS; KINETICS; LYSIS; MIXTURES; PEPTIDE HORMONES; RADIATION CHEMISTRY; RADIATION EFFECTS; RADIATIONS; REACTION KINETICS; SOLUTIONS; SOLVOLYSIS; 560111* - Radiation Effects on Biochemicals- In Vitro- (-1987); 400600 - Radiation Chemistry
OSTI ID:
7300344
Country of Origin:
Serbia and Montenegro
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: CCCCA
Submitting Site:
INIS
Size:
Pages: 2151-2158
Announcement Date:

Journal Article:

Citation Formats

Foitik, A, and Kopoldova, J. Radiolysis of aqueous solutions of insulin. [. gamma. rays]. Serbia and Montenegro: N. p., 1976. Web.
Foitik, A, & Kopoldova, J. Radiolysis of aqueous solutions of insulin. [. gamma. rays]. Serbia and Montenegro.
Foitik, A, and Kopoldova, J. 1976. "Radiolysis of aqueous solutions of insulin. [. gamma. rays]." Serbia and Montenegro.
@misc{etde_7300344,
title = {Radiolysis of aqueous solutions of insulin. [. gamma. rays]}
author = {Foitik, A, and Kopoldova, J}
abstractNote = {The effect of ionizing radiation on diluted aqueous solutions of insulin is analyzed. The rate of decrease in its level (the loss of polarographic activity) is described by a first-order kinetic equation. The results lead to the concept of a direct effect on macromolecules in 'excited volumes'. The amount of inactivated molecules (i.e., the yield) in this volume is proportional to the solute concentration. In diluted aqueous solutions indirect radiation effects also take place. The paper evaluates these effects.}
journal = {Collect. Czech. Chem. Commun.; (Czechoslovakia)}
volume = {41:8}
journal type = {AC}
place = {Serbia and Montenegro}
year = {1976}
month = {Aug}
}