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Peroxides and radiation impairment of oxidative phosphorylation

Journal Article:

Abstract

An increase in the peroxidase activity of the mitochondria and a simultaneous rise in the amount of peroxide compounds, which are half lipid-like substances, are detected within the first 10 minutes after irradiation (1000 r). A mechanism of radiation impairment of oxidative phosphorylation is connected with the penetration of its inhibitors to the mitochondria due to the disturbed permeability of membranes affected by peroxides.
Publication Date:
Sep 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-08-328036; EDB-77-148199
Resource Relation:
Journal Name: Radiobiologiya; (USSR); Journal Volume: 15:5; Other Information: For English translation see the journal Radiobiology
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; CELL MEMBRANES; PERMEABILITY; MITOCHONDRIA; PHOSPHORYLATION; PEROXIDES; RADIOSENSITIVITY EFFECTS; BIOLOGICAL RADIATION EFFECTS; DOSE RATES; IONIZING RADIATIONS; LIVER; OXIDATION; PEROXIDASES; RATS; REACTION KINETICS; WHOLE-BODY IRRADIATION; ANIMALS; BIOLOGICAL EFFECTS; BODY; CARBOXYLIC ACIDS; CELL CONSTITUENTS; CHEMICAL REACTIONS; DIGESTIVE SYSTEM; ENZYMES; EXTERNAL IRRADIATION; GLANDS; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; IRRADIATION; KINETICS; MAMMALS; MEMBRANES; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANOIDS; ORGANS; OXIDOREDUCTASES; OXYGEN COMPOUNDS; PORPHYRINS; RADIATION EFFECTS; RADIATIONS; RODENTS; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
7289182
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: RADOA
Submitting Site:
INIS
Size:
Pages: 730-732
Announcement Date:

Journal Article:

Citation Formats

Dovgii, I E, and Akoev, I G. Peroxides and radiation impairment of oxidative phosphorylation. USSR: N. p., 1975. Web.
Dovgii, I E, & Akoev, I G. Peroxides and radiation impairment of oxidative phosphorylation. USSR.
Dovgii, I E, and Akoev, I G. 1975. "Peroxides and radiation impairment of oxidative phosphorylation." USSR.
@misc{etde_7289182,
title = {Peroxides and radiation impairment of oxidative phosphorylation}
author = {Dovgii, I E, and Akoev, I G}
abstractNote = {An increase in the peroxidase activity of the mitochondria and a simultaneous rise in the amount of peroxide compounds, which are half lipid-like substances, are detected within the first 10 minutes after irradiation (1000 r). A mechanism of radiation impairment of oxidative phosphorylation is connected with the penetration of its inhibitors to the mitochondria due to the disturbed permeability of membranes affected by peroxides.}
journal = {Radiobiologiya; (USSR)}
volume = {15:5}
journal type = {AC}
place = {USSR}
year = {1975}
month = {Sep}
}