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Immunological half-life of porcine proinsulin C-peptide

Abstract

Immunological half-lifes of injected porcine C-peptide and insulin with RIA were studied and calculated as 9.8 and 8.0 minutes. Higher circulating levels of C-peptide as compared to insulin in normal young swines lead to speculation about a longer half-life of C-peptide. This hypothesis was verified in this study. Immunological half-lifes of porcine proinsulin and insulin in the pig were 20 and 6 minutes, respectively.
Authors:
Oyama, H; Horino, M; Matsumura, S; [1]  Kobayshi, K; Suetsugu, N [2] 
  1. Kawasaki Medical Coll., Kurashiki (Japan). Div. of Endocrinology
  2. Yamaguchi Univ., Ube (Japan). School of Medicine
Publication Date:
Nov 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-255716; EDB-76-098899
Resource Relation:
Journal Name: Horm. Metab. Res.; (Germany, Federal Republic of); Journal Volume: 7:6; Other Information: 1 fig.; 4 refs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; INSULIN; RADIOIMMUNOASSAY; PEPTIDES; AGE DEPENDENCE; BIOLOGICAL HALF-LIFE; LABELLED COMPOUNDS; METABOLISM; PANCREAS; REACTION KINETICS; SWINE; ANIMALS; BODY; DIGESTIVE SYSTEM; DOMESTIC ANIMALS; ENDOCRINE GLANDS; GLANDS; HORMONES; ISOTOPE APPLICATIONS; KINETICS; MAMMALS; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HORMONES; PROTEINS; RADIOASSAY; TRACER TECHNIQUES; VERTEBRATES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7261980
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: HMMRA
Submitting Site:
INIS
Size:
Pages: 520-521
Announcement Date:
Sep 01, 1976

Citation Formats

Oyama, H, Horino, M, Matsumura, S, Kobayshi, K, and Suetsugu, N. Immunological half-life of porcine proinsulin C-peptide. Germany: N. p., 1975. Web.
Oyama, H, Horino, M, Matsumura, S, Kobayshi, K, & Suetsugu, N. Immunological half-life of porcine proinsulin C-peptide. Germany.
Oyama, H, Horino, M, Matsumura, S, Kobayshi, K, and Suetsugu, N. 1975. "Immunological half-life of porcine proinsulin C-peptide." Germany.
@misc{etde_7261980,
title = {Immunological half-life of porcine proinsulin C-peptide}
author = {Oyama, H, Horino, M, Matsumura, S, Kobayshi, K, and Suetsugu, N}
abstractNote = {Immunological half-lifes of injected porcine C-peptide and insulin with RIA were studied and calculated as 9.8 and 8.0 minutes. Higher circulating levels of C-peptide as compared to insulin in normal young swines lead to speculation about a longer half-life of C-peptide. This hypothesis was verified in this study. Immunological half-lifes of porcine proinsulin and insulin in the pig were 20 and 6 minutes, respectively.}
journal = []
volume = {7:6}
journal type = {AC}
place = {Germany}
year = {1975}
month = {Nov}
}