Abstract
The concentration of trimethoprim and sulphadoxine in plasma and tissue from goats and a cow have been determined after a single intravenous injection. Furthermore, the concentration of the two drugs and their metabolites in plasma and tissues have been determined after continuous intravenous infusion for 2 1/2 - 3 hrs. Trimethoprim was present in all tissues but brain at higher concentrations than in plasma while the concentration of sulphadoxine in the different tissues were lower than in plasma. The highest concentration of the 2 drugs and their metabolites was found in the kidney. The distribution pattern of trimethoprim and sulphadoxine was similar in cow and goats.
Citation Formats
Nielsen, P, and Rasmussen, F.
Concentrations of trimethoprim and sulphadoxine in tissues from goats and a cow.
Denmark: N. p.,
1975.
Web.
Nielsen, P, & Rasmussen, F.
Concentrations of trimethoprim and sulphadoxine in tissues from goats and a cow.
Denmark.
Nielsen, P, and Rasmussen, F.
1975.
"Concentrations of trimethoprim and sulphadoxine in tissues from goats and a cow."
Denmark.
@misc{etde_7250997,
title = {Concentrations of trimethoprim and sulphadoxine in tissues from goats and a cow}
author = {Nielsen, P, and Rasmussen, F}
abstractNote = {The concentration of trimethoprim and sulphadoxine in plasma and tissue from goats and a cow have been determined after a single intravenous injection. Furthermore, the concentration of the two drugs and their metabolites in plasma and tissues have been determined after continuous intravenous infusion for 2 1/2 - 3 hrs. Trimethoprim was present in all tissues but brain at higher concentrations than in plasma while the concentration of sulphadoxine in the different tissues were lower than in plasma. The highest concentration of the 2 drugs and their metabolites was found in the kidney. The distribution pattern of trimethoprim and sulphadoxine was similar in cow and goats.}
journal = []
volume = {16}
journal type = {AC}
place = {Denmark}
year = {1975}
month = {Jan}
}
title = {Concentrations of trimethoprim and sulphadoxine in tissues from goats and a cow}
author = {Nielsen, P, and Rasmussen, F}
abstractNote = {The concentration of trimethoprim and sulphadoxine in plasma and tissue from goats and a cow have been determined after a single intravenous injection. Furthermore, the concentration of the two drugs and their metabolites in plasma and tissues have been determined after continuous intravenous infusion for 2 1/2 - 3 hrs. Trimethoprim was present in all tissues but brain at higher concentrations than in plasma while the concentration of sulphadoxine in the different tissues were lower than in plasma. The highest concentration of the 2 drugs and their metabolites was found in the kidney. The distribution pattern of trimethoprim and sulphadoxine was similar in cow and goats.}
journal = []
volume = {16}
journal type = {AC}
place = {Denmark}
year = {1975}
month = {Jan}
}