Abstract
In the first part of the dissertation, the physiological arsenic content of 50 normal and 50 pathologically altered pancreases was determined using a method proposed by VASAK and SEDIVEC and modified by ARNOLD and SCHROEDER. A mean arsenic content of 4.86 ..mu..g% (dry weight) was found. There were no significantly increased or reduced values between the two groups of organs. The results agreed with similar investigations of other organs. The method of determination proposed by VASAK, SEDIVEC was not sensitive enough for the second part of the work in which the uptake and elimination rate as well as, if necessary, the place of retention of very small amounts of arsenic applied to mice as measured. The application of small amounts of radioactive /sup 74/As and subsequent measurements in a well-type scintillation counter showed a fast uptake in the major metabolic organs followed by equally fast elimination. Storage of As was not observed in the organs under investigation.
Citation Formats
Graeper, P.
Investigations of arsenic metabolism. The physiological arsenic content in normal and pathologically alterated pancreas. Uptake and excretion of arsenic (/sup 74/As) in mice in consideration with regard to the excretion time.
Germany: N. p.,
1974.
Web.
Graeper, P.
Investigations of arsenic metabolism. The physiological arsenic content in normal and pathologically alterated pancreas. Uptake and excretion of arsenic (/sup 74/As) in mice in consideration with regard to the excretion time.
Germany.
Graeper, P.
1974.
"Investigations of arsenic metabolism. The physiological arsenic content in normal and pathologically alterated pancreas. Uptake and excretion of arsenic (/sup 74/As) in mice in consideration with regard to the excretion time."
Germany.
@misc{etde_7238536,
title = {Investigations of arsenic metabolism. The physiological arsenic content in normal and pathologically alterated pancreas. Uptake and excretion of arsenic (/sup 74/As) in mice in consideration with regard to the excretion time}
author = {Graeper, P}
abstractNote = {In the first part of the dissertation, the physiological arsenic content of 50 normal and 50 pathologically altered pancreases was determined using a method proposed by VASAK and SEDIVEC and modified by ARNOLD and SCHROEDER. A mean arsenic content of 4.86 ..mu..g% (dry weight) was found. There were no significantly increased or reduced values between the two groups of organs. The results agreed with similar investigations of other organs. The method of determination proposed by VASAK, SEDIVEC was not sensitive enough for the second part of the work in which the uptake and elimination rate as well as, if necessary, the place of retention of very small amounts of arsenic applied to mice as measured. The application of small amounts of radioactive /sup 74/As and subsequent measurements in a well-type scintillation counter showed a fast uptake in the major metabolic organs followed by equally fast elimination. Storage of As was not observed in the organs under investigation.}
place = {Germany}
year = {1974}
month = {Jan}
}
title = {Investigations of arsenic metabolism. The physiological arsenic content in normal and pathologically alterated pancreas. Uptake and excretion of arsenic (/sup 74/As) in mice in consideration with regard to the excretion time}
author = {Graeper, P}
abstractNote = {In the first part of the dissertation, the physiological arsenic content of 50 normal and 50 pathologically altered pancreases was determined using a method proposed by VASAK and SEDIVEC and modified by ARNOLD and SCHROEDER. A mean arsenic content of 4.86 ..mu..g% (dry weight) was found. There were no significantly increased or reduced values between the two groups of organs. The results agreed with similar investigations of other organs. The method of determination proposed by VASAK, SEDIVEC was not sensitive enough for the second part of the work in which the uptake and elimination rate as well as, if necessary, the place of retention of very small amounts of arsenic applied to mice as measured. The application of small amounts of radioactive /sup 74/As and subsequent measurements in a well-type scintillation counter showed a fast uptake in the major metabolic organs followed by equally fast elimination. Storage of As was not observed in the organs under investigation.}
place = {Germany}
year = {1974}
month = {Jan}
}