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Radioimmunologic analysis of insulin secretion during acute radiation sickness

Journal Article:

Abstract

Rats were subjected to whole-body gamma irradiation (750 rad) and the secretory activity of the insular apparatus was studied radioimmunologically, using insulin labelled with iodine-125. The post-radiation dynamics of the insulin concentration in the blood were shown to have a phase character. The insulin level had risen after 1, 3 and 8 days. After 2 days the hormone concentration had dropped significantly and become two times lower than normal. After the other time intervals, the concentration of insulin in the blood varied within normal limits.
Authors:
Publication Date:
Jan 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-08-289947; EDB-77-045452
Resource Relation:
Journal Name: Radiobiologiya; (USSR); Journal Volume: 15:1; Other Information: For English translation see the journal Radiobiology
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; INSULIN; BIOLOGICAL RADIATION EFFECTS; RADIOIMMUNOASSAY; BLOOD; GAMMA RADIATION; IODINE 125; RADIATION DOSES; RADIATION SYNDROME; RATS; TIME DEPENDENCE; WHOLE-BODY IRRADIATION; ANIMALS; BETA DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BODY FLUIDS; DAYS LIVING RADIOISOTOPES; DOSES; ELECTROMAGNETIC RADIATION; ELECTRON CAPTURE RADIOISOTOPES; EXTERNAL IRRADIATION; HORMONES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; IONIZING RADIATIONS; IRRADIATION; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; NUCLEI; ODD-EVEN NUCLEI; PEPTIDE HORMONES; RADIATION EFFECTS; RADIATIONS; RADIOASSAY; RADIOISOTOPES; RODENTS; TRACER TECHNIQUES; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals; 550601 - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7234016
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: RADOA
Submitting Site:
INIS
Size:
Pages: 127-129
Announcement Date:

Journal Article:

Citation Formats

Barkalaya, A I. Radioimmunologic analysis of insulin secretion during acute radiation sickness. USSR: N. p., 1975. Web.
Barkalaya, A I. Radioimmunologic analysis of insulin secretion during acute radiation sickness. USSR.
Barkalaya, A I. 1975. "Radioimmunologic analysis of insulin secretion during acute radiation sickness." USSR.
@misc{etde_7234016,
title = {Radioimmunologic analysis of insulin secretion during acute radiation sickness}
author = {Barkalaya, A I}
abstractNote = {Rats were subjected to whole-body gamma irradiation (750 rad) and the secretory activity of the insular apparatus was studied radioimmunologically, using insulin labelled with iodine-125. The post-radiation dynamics of the insulin concentration in the blood were shown to have a phase character. The insulin level had risen after 1, 3 and 8 days. After 2 days the hormone concentration had dropped significantly and become two times lower than normal. After the other time intervals, the concentration of insulin in the blood varied within normal limits.}
journal = {Radiobiologiya; (USSR)}
volume = {15:1}
journal type = {AC}
place = {USSR}
year = {1975}
month = {Jan}
}