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Effect of air pollutants on ciliary activity of respiratory tract

Journal Article:

Abstract

The effect of sulfur dioxide, nitrogen dioxide, nitric oxide, ozone, and formaldehyde on the ciliary activity of an excised specimen of the trachea of a guinea pig was investigated. The influence of these gases is determined by the Half Reduction Time of the ciliary activity, which is the time lapse from the beginning of the gas exposure at a certain concentration to the point of which the activity is reduced by half. The Half Reduction Time of the ciliary activity by each gas at the concentration of 50 ppM is SO/sub 2/, 4 min; HCHO, 5 min; NO/sub 2/, 10 min; NO, 14 min; and O/sub 3/, 20 min. The influence of the easily water soluble gases such as SO/sub 2/ and HCHO on the ciliary activity is severe compared with the less water soluble ones, NO/sub 2/ and O/sub 3/, which pass over the mucous surface of the upper airway without dissolving to the mucous layer.
Authors:
Publication Date:
Dec 01, 1974
Product Type:
Journal Article
Reference Number:
EDB-77-045536
Resource Relation:
Journal Name: Bull. Tokyo Med. Dent. Univ.; (Japan); Journal Volume: 21:4
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; AIR POLLUTION; HEALTH HAZARDS; TRACHEA; PATHOLOGICAL CHANGES; BIOLOGICAL EFFECTS; FORMALDEHYDE; GUINEA PIGS; NITRIC OXIDE; NITROGEN DIOXIDE; OZONE; RESPIRATORY SYSTEM; SULFUR DIOXIDE; ALDEHYDES; ANIMALS; CHALCOGENIDES; DISEASES; HAZARDS; MAMMALS; NITROGEN COMPOUNDS; NITROGEN OXIDES; ORGANIC COMPOUNDS; OXIDES; OXYGEN COMPOUNDS; POLLUTION; RODENTS; SULFUR COMPOUNDS; SULFUR OXIDES; VERTEBRATES; 560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
OSTI ID:
7233984
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: BTMDA
Submitting Site:
APA
Size:
Pages: 327-343
Announcement Date:

Journal Article:

Citation Formats

Omachi, S, and Kita, H. Effect of air pollutants on ciliary activity of respiratory tract. Japan: N. p., 1974. Web.
Omachi, S, & Kita, H. Effect of air pollutants on ciliary activity of respiratory tract. Japan.
Omachi, S, and Kita, H. 1974. "Effect of air pollutants on ciliary activity of respiratory tract." Japan.
@misc{etde_7233984,
title = {Effect of air pollutants on ciliary activity of respiratory tract}
author = {Omachi, S, and Kita, H}
abstractNote = {The effect of sulfur dioxide, nitrogen dioxide, nitric oxide, ozone, and formaldehyde on the ciliary activity of an excised specimen of the trachea of a guinea pig was investigated. The influence of these gases is determined by the Half Reduction Time of the ciliary activity, which is the time lapse from the beginning of the gas exposure at a certain concentration to the point of which the activity is reduced by half. The Half Reduction Time of the ciliary activity by each gas at the concentration of 50 ppM is SO/sub 2/, 4 min; HCHO, 5 min; NO/sub 2/, 10 min; NO, 14 min; and O/sub 3/, 20 min. The influence of the easily water soluble gases such as SO/sub 2/ and HCHO on the ciliary activity is severe compared with the less water soluble ones, NO/sub 2/ and O/sub 3/, which pass over the mucous surface of the upper airway without dissolving to the mucous layer.}
journal = {Bull. Tokyo Med. Dent. Univ.; (Japan)}
volume = {21:4}
journal type = {AC}
place = {Japan}
year = {1974}
month = {Dec}
}