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Diagnostics of the myocardium with radionuclides

Abstract

Three aspects allow description of myocardial functional state: perfusion, motility and disturbance of structure, to all of which nuclear medicine can provide information. Distribution of /sup 201/thallium reflects myocardial perfusion distribution. Diminished accumulation of radioactive kalium, rubidium, caesium on thallium is correlated to reduced or abolished perfusion in areas of destroyed myocardial structure (infarction), the latter is marked by increased sup(99m)Tc-pyrophosphate-uptake caused by increased permeability of cellular membranes. Motility can be described globally or regionally by analysis or regional wall motion. Among global parameters ejection fraction as a measure for diminished myocardial contractility was of great interest. However, parameters for evaluation of regional myocardial motility are in the centre of interest. Camera-cinematography is the approach to analyse precordial countrate changes as time volume equivalents caused by cyclic cardial volume changes. The results allow to deliniate areas of hypokinesis and akinesis, areas of dyskinesis with phase shifting in comparison to normokinetic areas, at least evaluation of dV/dtsub(max) for contractility and relaxation. The results of normal subjects without heart disease show excellent reproducibility with strong correlation. The results of 165 patients suspected to have coronary heart disease or vitium cordis delivered additional information in part, in 27 of 29 cases results were  More>>
Authors:
Adam, W E; Geffers, H; Sigel, H; Kampmann, H; Stauch, M [1] 
  1. Ulm Univ. (Germany, F.R.). Sektion Nuklearmedizin
Publication Date:
Nov 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-08-306332; EDB-77-108774
Resource Relation:
Journal Name: Nucl. Act.; (Germany, Federal Republic of); Journal Volume: 7:5; Other Information: 3 figs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; MYOCARDIUM; DIAGNOSTIC TECHNIQUES; BLOOD CIRCULATION; DIAGNOSIS; ISOMERIC NUCLEI; MYOCARDIAL INFARCTION; PHOSPHORUS COMPOUNDS; RADIONUCLIDE KINETICS; SCINTISCANNING; TECHNETIUM 99; THALLIUM 201; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; HEART; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MUSCLES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; SECONDS LIVING RADIOISOTOPES; TECHNETIUM ISOTOPES; THALLIUM ISOTOPES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7212874
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: NULAB
Submitting Site:
INIS
Size:
Pages: 135-144
Announcement Date:
Aug 01, 1977

Citation Formats

Adam, W E, Geffers, H, Sigel, H, Kampmann, H, and Stauch, M. Diagnostics of the myocardium with radionuclides. Germany: N. p., 1976. Web.
Adam, W E, Geffers, H, Sigel, H, Kampmann, H, & Stauch, M. Diagnostics of the myocardium with radionuclides. Germany.
Adam, W E, Geffers, H, Sigel, H, Kampmann, H, and Stauch, M. 1976. "Diagnostics of the myocardium with radionuclides." Germany.
@misc{etde_7212874,
title = {Diagnostics of the myocardium with radionuclides}
author = {Adam, W E, Geffers, H, Sigel, H, Kampmann, H, and Stauch, M}
abstractNote = {Three aspects allow description of myocardial functional state: perfusion, motility and disturbance of structure, to all of which nuclear medicine can provide information. Distribution of /sup 201/thallium reflects myocardial perfusion distribution. Diminished accumulation of radioactive kalium, rubidium, caesium on thallium is correlated to reduced or abolished perfusion in areas of destroyed myocardial structure (infarction), the latter is marked by increased sup(99m)Tc-pyrophosphate-uptake caused by increased permeability of cellular membranes. Motility can be described globally or regionally by analysis or regional wall motion. Among global parameters ejection fraction as a measure for diminished myocardial contractility was of great interest. However, parameters for evaluation of regional myocardial motility are in the centre of interest. Camera-cinematography is the approach to analyse precordial countrate changes as time volume equivalents caused by cyclic cardial volume changes. The results allow to deliniate areas of hypokinesis and akinesis, areas of dyskinesis with phase shifting in comparison to normokinetic areas, at least evaluation of dV/dtsub(max) for contractility and relaxation. The results of normal subjects without heart disease show excellent reproducibility with strong correlation. The results of 165 patients suspected to have coronary heart disease or vitium cordis delivered additional information in part, in 27 of 29 cases results were identical to conventional invasive cineangiography. Comparison of ejection fraction measured scintigraphically and ventriculographically with the area-diameter-method revealed excellent correlation (r = 0,93).}
journal = []
volume = {7:5}
journal type = {AC}
place = {Germany}
year = {1976}
month = {Nov}
}