You need JavaScript to view this

Distribution of heparin-/sup 67/Ga in tumor-bearing rats

Journal Article:

Abstract

Heparin is a kind of acidic mucopolysaccharide. The distribution of heparin-/sup 67/Ga complex in tumor-bearing rats was investigated by administering it to rats into which Yoshida sarcoma had been transplanted subcutaneously. These rats were sacrificed at 10 minutes, 30 minutes, 1 hour and 3 hours after injection. Radioactivity of the tumor, blood, muscle, liver, kidney, spleen and urine were measured with a well-type scintillation counter. Retention values in these organs and excretion rates in the urine were calculated. Excretion rates (%/dose) of heparin-/sup 67/Ga in 10 min., 30 min., 1 hour, and 3 hours were 38.2%, 67.5%, 79.5% and 78.0%, respectively. From these facts, it was thought that heparin-/sup 67/Ga complex was not suitable for tumor scanning, but that this compound might be a suitable agent for the renal function test.
Authors:
Hiraki, T; Ando, A; Sanada, S; [1]  Ando, I; Hisada, K
  1. Kanazawa Univ. (Japan). School of Paramedicine
Publication Date:
Jun 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-08-321727; EDB-77-115214
Resource Relation:
Journal Name: Radioisotopes (Tokyo); (Japan); Journal Volume: 25:6
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; EXPERIMENTAL NEOPLASMS; RADIONUCLIDE KINETICS; GALLIUM 67; TISSUE DISTRIBUTION; UPTAKE; DISTRIBUTION; EXCRETION; HEPARIN; KIDNEYS; RADIOPHARMACEUTICALS; RATS; URINE; AMINES; ANIMALS; ANTICOAGULANTS; BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BIOLOGICAL WASTES; BODY; BODY FLUIDS; CARBOHYDRATES; CLEARANCE; DAYS LIVING RADIOISOTOPES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; GALLIUM ISOTOPES; INTERMEDIATE MASS NUCLEI; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MUCOPOLYSACCHARIDES; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; ORGANS; POLYSACCHARIDES; RADIOACTIVE MATERIALS; RADIOISOTOPES; RODENTS; SACCHARIDES; VERTEBRATES; WASTES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7210902
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: RAISA
Submitting Site:
INIS
Size:
Pages: 329-332
Announcement Date:
Aug 01, 1977

Journal Article:

Citation Formats

Hiraki, T, Ando, A, Sanada, S, Ando, I, and Hisada, K. Distribution of heparin-/sup 67/Ga in tumor-bearing rats. Japan: N. p., 1976. Web.
Hiraki, T, Ando, A, Sanada, S, Ando, I, & Hisada, K. Distribution of heparin-/sup 67/Ga in tumor-bearing rats. Japan.
Hiraki, T, Ando, A, Sanada, S, Ando, I, and Hisada, K. 1976. "Distribution of heparin-/sup 67/Ga in tumor-bearing rats." Japan.
@misc{etde_7210902,
title = {Distribution of heparin-/sup 67/Ga in tumor-bearing rats}
author = {Hiraki, T, Ando, A, Sanada, S, Ando, I, and Hisada, K}
abstractNote = {Heparin is a kind of acidic mucopolysaccharide. The distribution of heparin-/sup 67/Ga complex in tumor-bearing rats was investigated by administering it to rats into which Yoshida sarcoma had been transplanted subcutaneously. These rats were sacrificed at 10 minutes, 30 minutes, 1 hour and 3 hours after injection. Radioactivity of the tumor, blood, muscle, liver, kidney, spleen and urine were measured with a well-type scintillation counter. Retention values in these organs and excretion rates in the urine were calculated. Excretion rates (%/dose) of heparin-/sup 67/Ga in 10 min., 30 min., 1 hour, and 3 hours were 38.2%, 67.5%, 79.5% and 78.0%, respectively. From these facts, it was thought that heparin-/sup 67/Ga complex was not suitable for tumor scanning, but that this compound might be a suitable agent for the renal function test.}
journal = {Radioisotopes (Tokyo); (Japan)}
volume = {25:6}
journal type = {AC}
place = {Japan}
year = {1976}
month = {Jun}
}