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Evaluation of freshly irradiated wheat for dominant lethal mutations in Wistar rats

Abstract

Three independent, serially performed experiments involving acute and chronic feeding of freshly irradiated wheat (75 krad, gamma-irradiation) were carried out in Wistar rats. In the first experiment groups of 10 males were given wheat for 1 week; irradiated wheat was consumed by the animals within 24 h of irradiation. In the other two experiments feeding of males was continued for 6 (10 males per group) and 12 (13 males per group) weeks, respectively, and the irradiated wheat was fed within 7 days of irradiation. At the end of each treatment period each male was paired with 3 females for 7 days and sequentially at weekly intervals for 5 or 8 weeks. Females were killed and examined for live and dead implantations and corpora lutea. There were no differences between groups with regard to fertility nor was there any inter-group difference as regards pre- and post-implantation losses whether the rats were fed irradiated or non-irradiated wheat. This suggested that even feeding of freshly irradiated wheat does not induce any dominant lethal mutations in rats.
Authors:
Pawan, S C; Aravindakshan, M; Kumar, N S; Subba Rao, V; Aiyar, A S; Sundaram, K [1] 
  1. Bhabha Atomic Research Centre, Bombay (India). Bio-medical Group
Publication Date:
Jan 01, 1977
Product Type:
Journal Article
Reference Number:
AIX-08-324598; EDB-78-018226
Resource Relation:
Journal Name: Toxicology; (Ireland); Journal Volume: 7:1
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; RATS; GENETIC RADIATION EFFECTS; FERTILITY; GAMMA RADIATION; IN VIVO; IRRADIATION; LETHAL MUTATIONS; TOXICITY; WHEAT; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BIOMASS; CEREALS; ELECTROMAGNETIC RADIATION; ENERGY SOURCES; GENETIC EFFECTS; GRAMINEAE; GRASS; IONIZING RADIATIONS; MAMMALS; MUTATIONS; PLANTS; RADIATION EFFECTS; RADIATIONS; RENEWABLE ENERGY SOURCES; RODENTS; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
7208514
Country of Origin:
Ireland
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: TXCYA
Submitting Site:
INIS
Size:
Pages: 85-97
Announcement Date:
Oct 01, 1977

Citation Formats

Pawan, S C, Aravindakshan, M, Kumar, N S, Subba Rao, V, Aiyar, A S, and Sundaram, K. Evaluation of freshly irradiated wheat for dominant lethal mutations in Wistar rats. Ireland: N. p., 1977. Web.
Pawan, S C, Aravindakshan, M, Kumar, N S, Subba Rao, V, Aiyar, A S, & Sundaram, K. Evaluation of freshly irradiated wheat for dominant lethal mutations in Wistar rats. Ireland.
Pawan, S C, Aravindakshan, M, Kumar, N S, Subba Rao, V, Aiyar, A S, and Sundaram, K. 1977. "Evaluation of freshly irradiated wheat for dominant lethal mutations in Wistar rats." Ireland.
@misc{etde_7208514,
title = {Evaluation of freshly irradiated wheat for dominant lethal mutations in Wistar rats}
author = {Pawan, S C, Aravindakshan, M, Kumar, N S, Subba Rao, V, Aiyar, A S, and Sundaram, K}
abstractNote = {Three independent, serially performed experiments involving acute and chronic feeding of freshly irradiated wheat (75 krad, gamma-irradiation) were carried out in Wistar rats. In the first experiment groups of 10 males were given wheat for 1 week; irradiated wheat was consumed by the animals within 24 h of irradiation. In the other two experiments feeding of males was continued for 6 (10 males per group) and 12 (13 males per group) weeks, respectively, and the irradiated wheat was fed within 7 days of irradiation. At the end of each treatment period each male was paired with 3 females for 7 days and sequentially at weekly intervals for 5 or 8 weeks. Females were killed and examined for live and dead implantations and corpora lutea. There were no differences between groups with regard to fertility nor was there any inter-group difference as regards pre- and post-implantation losses whether the rats were fed irradiated or non-irradiated wheat. This suggested that even feeding of freshly irradiated wheat does not induce any dominant lethal mutations in rats.}
journal = {Toxicology; (Ireland)}
volume = {7:1}
journal type = {AC}
place = {Ireland}
year = {1977}
month = {Jan}
}