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Minimum concentrations of NO/sub 2/ causing acute effects on the respiratory gas exchange and airway-resistance in patients with chronic bronchitis

Abstract

Nitrogen dioxide-air mixtures containing 0.5 to 5.0 ppM NO/sub 2/ were inhaled by 88 patients with chronic bronchitis over a 15-minute period for a total of 30 breaths during studies investigating the effects of the gas on airway resistance and respiratory gas exchange. End-expiratory oxygen pressures remained nearly constant during inhalation of 4 or 5 ppM NO/sub 2/, though significant decreases in arterial oxygen pressure accompanied by increases in end-expiratory-arterial oxygen pressure difference occurred. Inhalation of 2 ppM NO/sub 2/ did not decrease arterial oxygen pressure. Airway resistances increased significantly down to 1.5 ppM NO/sub 2/ concentrations. Lower concentrations caused no significant effects.
Publication Date:
Jan 01, 1971
Product Type:
Journal Article
Reference Number:
EDB-78-018325
Resource Relation:
Journal Name: Int. Arch. Arbeitsmed.; (Germany, Federal Republic of); Journal Volume: 27
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; NITROGEN DIOXIDE; BIOLOGICAL EFFECTS; AIR; ARTERIES; BRONCHITIS; INHALATION; OXYGEN; PATIENTS; PRESSURE DROP; RESPIRATION; BLOOD VESSELS; CARDIOVASCULAR SYSTEM; CHALCOGENIDES; CRYOGENIC FLUIDS; DISEASES; ELEMENTS; FLUIDS; GASES; INTAKE; NITROGEN COMPOUNDS; NITROGEN OXIDES; NONMETALS; OXIDES; OXYGEN COMPOUNDS; RESPIRATORY SYSTEM DISEASES; 560306* - Chemicals Metabolism & Toxicology- Man- (-1987); 550900 - Pathology
OSTI ID:
7208498
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: IAANB
Submitting Site:
APA
Size:
Pages: 338-348
Announcement Date:
Jan 01, 1978

Citation Formats

von Nieding, G, Wagner, M, Krekeler, H, Smidt, U, and Muysers, K. Minimum concentrations of NO/sub 2/ causing acute effects on the respiratory gas exchange and airway-resistance in patients with chronic bronchitis. Germany: N. p., 1971. Web. doi:10.1007/BF00539365.
von Nieding, G, Wagner, M, Krekeler, H, Smidt, U, & Muysers, K. Minimum concentrations of NO/sub 2/ causing acute effects on the respiratory gas exchange and airway-resistance in patients with chronic bronchitis. Germany. https://doi.org/10.1007/BF00539365
von Nieding, G, Wagner, M, Krekeler, H, Smidt, U, and Muysers, K. 1971. "Minimum concentrations of NO/sub 2/ causing acute effects on the respiratory gas exchange and airway-resistance in patients with chronic bronchitis." Germany. https://doi.org/10.1007/BF00539365.
@misc{etde_7208498,
title = {Minimum concentrations of NO/sub 2/ causing acute effects on the respiratory gas exchange and airway-resistance in patients with chronic bronchitis}
author = {von Nieding, G, Wagner, M, Krekeler, H, Smidt, U, and Muysers, K}
abstractNote = {Nitrogen dioxide-air mixtures containing 0.5 to 5.0 ppM NO/sub 2/ were inhaled by 88 patients with chronic bronchitis over a 15-minute period for a total of 30 breaths during studies investigating the effects of the gas on airway resistance and respiratory gas exchange. End-expiratory oxygen pressures remained nearly constant during inhalation of 4 or 5 ppM NO/sub 2/, though significant decreases in arterial oxygen pressure accompanied by increases in end-expiratory-arterial oxygen pressure difference occurred. Inhalation of 2 ppM NO/sub 2/ did not decrease arterial oxygen pressure. Airway resistances increased significantly down to 1.5 ppM NO/sub 2/ concentrations. Lower concentrations caused no significant effects.}
doi = {10.1007/BF00539365}
journal = []
volume = {27}
journal type = {AC}
place = {Germany}
year = {1971}
month = {Jan}
}