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Long term results of ultrasonically guided implantation of 125-I seeds combined with external irradiation in localized prostatic cancer

Journal Article:

Abstract

Transperineal 125-iodine seed implantation guided by transrectal ultrasonography and subsequent external beam irradiation was employed in the treatment of 32 patients with localized prostatic carcinoma (16 poorly differentiated). Follow-up is currently 35-98 months with a median of 65 months. Distant metastases have developed in 18 patients, of whom 11 have died from prostatic cancer. Median change in prostatic volume was a reduction of 35%. Re-biopsy or transurethral resection of the prostate was performed in 25 patients after 1-4 years, revealing still malignant histology in 10 (40%), of whom 8 have developed distant metastases or died from prostatic cancer. Fourteen patients suffered from late complications of which surgical intervention was indicated in five cases. Nine patients are presently free of progression and prostate specific antigen is bigger than 0.5 ng/ml in 8 of these. The future role of ultrasonically guided implantation in the management of prostatic cancer is discussed. (au).
Authors:
Iversen, P; Rasmussen, F; Holm, H H [1] 
  1. Depts. of Urology and Ultrasound, Herlev Hospital, Univ. of Copenhagen (Denmark)
Publication Date:
Jan 01, 1991
Product Type:
Journal Article
Reference Number:
AIX-23-086871; EDB-92-181326
Resource Relation:
Journal Name: Scandinavian Journal of Urology and Nephrology. Supplementum; (Sweden); Journal Volume: 138
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; PROSTATE; RADIATION SOURCE IMPLANTS; CARCINOMAS; DELAYED RADIATION EFFECTS; IODINE 125; PATIENTS; RADIOTHERAPY; ULTRASONOGRAPHY; BETA DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; DAYS LIVING RADIOISOTOPES; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; GLANDS; IMPLANTS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IODINE ISOTOPES; ISOTOPES; MALE GENITALS; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIATION EFFECTS; RADIATION SOURCES; RADIOISOTOPES; RADIOLOGY; THERAPY; 550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-)
OSTI ID:
7204330
Country of Origin:
Sweden
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0300-8886; CODEN: SJUNB
Submitting Site:
SWDN
Size:
Pages: 109-115
Announcement Date:
Dec 15, 1992

Journal Article:

Citation Formats

Iversen, P, Rasmussen, F, and Holm, H H. Long term results of ultrasonically guided implantation of 125-I seeds combined with external irradiation in localized prostatic cancer. Sweden: N. p., 1991. Web.
Iversen, P, Rasmussen, F, & Holm, H H. Long term results of ultrasonically guided implantation of 125-I seeds combined with external irradiation in localized prostatic cancer. Sweden.
Iversen, P, Rasmussen, F, and Holm, H H. 1991. "Long term results of ultrasonically guided implantation of 125-I seeds combined with external irradiation in localized prostatic cancer." Sweden.
@misc{etde_7204330,
title = {Long term results of ultrasonically guided implantation of 125-I seeds combined with external irradiation in localized prostatic cancer}
author = {Iversen, P, Rasmussen, F, and Holm, H H}
abstractNote = {Transperineal 125-iodine seed implantation guided by transrectal ultrasonography and subsequent external beam irradiation was employed in the treatment of 32 patients with localized prostatic carcinoma (16 poorly differentiated). Follow-up is currently 35-98 months with a median of 65 months. Distant metastases have developed in 18 patients, of whom 11 have died from prostatic cancer. Median change in prostatic volume was a reduction of 35%. Re-biopsy or transurethral resection of the prostate was performed in 25 patients after 1-4 years, revealing still malignant histology in 10 (40%), of whom 8 have developed distant metastases or died from prostatic cancer. Fourteen patients suffered from late complications of which surgical intervention was indicated in five cases. Nine patients are presently free of progression and prostate specific antigen is bigger than 0.5 ng/ml in 8 of these. The future role of ultrasonically guided implantation in the management of prostatic cancer is discussed. (au).}
journal = {Scandinavian Journal of Urology and Nephrology. Supplementum; (Sweden)}
volume = {138}
journal type = {AC}
place = {Sweden}
year = {1991}
month = {Jan}
}