Abstract
The effects of water-soluble oil fractions (WSFs) have been studied on the isolated heart of gastropods Strombus gigas and Bursatella leachi, in particular their effects on the myocardium and on its interaction with neuro transmitters: acetylcholine (ACh) and serotonin (5-HT). The WSFs were shown to be effective even when very diluted. The stock solution (10/sup -3/) was obtained by dissolving 1 ml of crude oil in 1 liter of sea water. The WSFs at concentrations of 10/sup -8/ to 10/sup -7/ and 10/sup -4/ to 10/sup -3/ increased the amplitude and frequency of heart contractions but at concentrations of 10/sup -6/ to 10/sup -5/ induced the cardiac arrest. These concentrations correspond to those occurring when the oil is dumped into the sea. The Ach effect was partially or completely blocked against the background of the stimulating effect of the WSFs and the inotropic effect of 5-HT was blocked at higher concentrations of the WSFs (up to 10/sup -3/). The higher the heart sensitivity to the transmitters, the stronger is the damaging effect of the WSFs. The data obtained suggest that oil, even when very diluted, affects the activity of the cardiac muscle and its nervous regulation.
Citation Formats
Berdysheva, L, Perez, R, and Valle, R.
Effects of water-soluble oil fractions on the heart of marine molluscs. [Strombus gigus, Bursatella leachi].
Hungary: N. p.,
1986.
Web.
Berdysheva, L, Perez, R, & Valle, R.
Effects of water-soluble oil fractions on the heart of marine molluscs. [Strombus gigus, Bursatella leachi].
Hungary.
Berdysheva, L, Perez, R, and Valle, R.
1986.
"Effects of water-soluble oil fractions on the heart of marine molluscs. [Strombus gigus, Bursatella leachi]."
Hungary.
@misc{etde_7194530,
title = {Effects of water-soluble oil fractions on the heart of marine molluscs. [Strombus gigus, Bursatella leachi]}
author = {Berdysheva, L, Perez, R, and Valle, R}
abstractNote = {The effects of water-soluble oil fractions (WSFs) have been studied on the isolated heart of gastropods Strombus gigas and Bursatella leachi, in particular their effects on the myocardium and on its interaction with neuro transmitters: acetylcholine (ACh) and serotonin (5-HT). The WSFs were shown to be effective even when very diluted. The stock solution (10/sup -3/) was obtained by dissolving 1 ml of crude oil in 1 liter of sea water. The WSFs at concentrations of 10/sup -8/ to 10/sup -7/ and 10/sup -4/ to 10/sup -3/ increased the amplitude and frequency of heart contractions but at concentrations of 10/sup -6/ to 10/sup -5/ induced the cardiac arrest. These concentrations correspond to those occurring when the oil is dumped into the sea. The Ach effect was partially or completely blocked against the background of the stimulating effect of the WSFs and the inotropic effect of 5-HT was blocked at higher concentrations of the WSFs (up to 10/sup -3/). The higher the heart sensitivity to the transmitters, the stronger is the damaging effect of the WSFs. The data obtained suggest that oil, even when very diluted, affects the activity of the cardiac muscle and its nervous regulation.}
journal = []
volume = {37}
place = {Hungary}
year = {1986}
month = {Jan}
}
title = {Effects of water-soluble oil fractions on the heart of marine molluscs. [Strombus gigus, Bursatella leachi]}
author = {Berdysheva, L, Perez, R, and Valle, R}
abstractNote = {The effects of water-soluble oil fractions (WSFs) have been studied on the isolated heart of gastropods Strombus gigas and Bursatella leachi, in particular their effects on the myocardium and on its interaction with neuro transmitters: acetylcholine (ACh) and serotonin (5-HT). The WSFs were shown to be effective even when very diluted. The stock solution (10/sup -3/) was obtained by dissolving 1 ml of crude oil in 1 liter of sea water. The WSFs at concentrations of 10/sup -8/ to 10/sup -7/ and 10/sup -4/ to 10/sup -3/ increased the amplitude and frequency of heart contractions but at concentrations of 10/sup -6/ to 10/sup -5/ induced the cardiac arrest. These concentrations correspond to those occurring when the oil is dumped into the sea. The Ach effect was partially or completely blocked against the background of the stimulating effect of the WSFs and the inotropic effect of 5-HT was blocked at higher concentrations of the WSFs (up to 10/sup -3/). The higher the heart sensitivity to the transmitters, the stronger is the damaging effect of the WSFs. The data obtained suggest that oil, even when very diluted, affects the activity of the cardiac muscle and its nervous regulation.}
journal = []
volume = {37}
place = {Hungary}
year = {1986}
month = {Jan}
}