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Effect of gamma irradiation on the activity of alanine and aspartate transaminases in subcellular fractions of the brain and heart in white rats

Journal Article:

Abstract

In experiments on rats, the activity of alanine (I) and aspartate transaminases (II) was studied in homogenates and subcellular fractions of the brain and myocardium under normal conditions and for 30 days after ..gamma.. irradiation at 40 rads. The activity of II in brain homogenates increased 1 hour after irradiation but decreased by 20 percent on day 3; it decreased again on days 7 and 15. The activity of brain I increased after 1 hour and 3 days but then returned to normal. The activity of I in heart homogenates increased in all the periods after irradiation. The subcellular fractions exhibited phase changes in the activity of the enzymes. These changes were different in nature from those observed after X and ..gamma.. irradiation at the same dose.
Authors:
Publication Date:
Jan 01, 1973
Product Type:
Journal Article
Reference Number:
EDB-76-055782
Resource Relation:
Journal Name: Aktual. Probl. Onkol. Med. Radiol.; (Byelorussian SSR); Journal Volume: 3
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ALANINES; BIOLOGICAL RADIATION EFFECTS; AMINOTRANSFERASES; BRAIN; MYOCARDIUM; ASPARTIC ACID; COMPARATIVE EVALUATIONS; GAMMA RADIATION; IRRADIATION; RATS; TIME DEPENDENCE; X RADIATION; AMINO ACIDS; ANIMALS; BIOLOGICAL EFFECTS; BODY; CARBOXYLIC ACIDS; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; ELECTROMAGNETIC RADIATION; ENZYMES; HEART; IONIZING RADIATIONS; MAMMALS; MUSCLES; NERVOUS SYSTEM; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; TRANSFERASES; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
7190254
Country of Origin:
Belarus
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: APORD
Submitting Site:
HEDB
Size:
Pages: 381-384
Announcement Date:

Journal Article:

Citation Formats

Plenin, A E. Effect of gamma irradiation on the activity of alanine and aspartate transaminases in subcellular fractions of the brain and heart in white rats. Belarus: N. p., 1973. Web.
Plenin, A E. Effect of gamma irradiation on the activity of alanine and aspartate transaminases in subcellular fractions of the brain and heart in white rats. Belarus.
Plenin, A E. 1973. "Effect of gamma irradiation on the activity of alanine and aspartate transaminases in subcellular fractions of the brain and heart in white rats." Belarus.
@misc{etde_7190254,
title = {Effect of gamma irradiation on the activity of alanine and aspartate transaminases in subcellular fractions of the brain and heart in white rats}
author = {Plenin, A E}
abstractNote = {In experiments on rats, the activity of alanine (I) and aspartate transaminases (II) was studied in homogenates and subcellular fractions of the brain and myocardium under normal conditions and for 30 days after ..gamma.. irradiation at 40 rads. The activity of II in brain homogenates increased 1 hour after irradiation but decreased by 20 percent on day 3; it decreased again on days 7 and 15. The activity of brain I increased after 1 hour and 3 days but then returned to normal. The activity of I in heart homogenates increased in all the periods after irradiation. The subcellular fractions exhibited phase changes in the activity of the enzymes. These changes were different in nature from those observed after X and ..gamma.. irradiation at the same dose.}
journal = {Aktual. Probl. Onkol. Med. Radiol.; (Byelorussian SSR)}
volume = {3}
journal type = {AC}
place = {Belarus}
year = {1973}
month = {Jan}
}