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Radioisotope studies of steroid hormone levels of plasma in indigenous subjects living at high altitude and submitted to a low calorie diet. Final report for the period of 1 April 1971--30 June 1975

Technical Report:

Abstract

Radioimmunological techniques were applied to the evaluation of TSH and ACTH in the four groups of Ecuadorian subjects under investigation at Tocachi, Malchingui, Quito and Portoviejo, the first three populations living at a high altitude and the fourth at sea-level. This evaluation was of interest since previous studies had indicated that there were thyroid and adrenal hormone deficiency levels in individuals from Tocachi and Malchingui or, in other words, in populations from a high-altitude region, and also endemic goitre and caloric-protein malnutrition. Furthermore, the Tocachi group was composed of subjects suffering from chronic ''stress''. Parallel to the analysis of TSH and pituitary ACTH levels, the circadian rhythm in the production of these hormones in these subjects was studied. The basal values of TSH and ACHT for the studied groups were found to lie within the normal range. /sup 131/I-TSH and /sup 125/I-ACTH were used. As far as the nycthemeral TSH rhythm is concerned, the values tended to be lowest for the high-altitude populations, while for the groups living at sea-level, where there is also circadian variation, the higher values are found in the morning. Similarly, the circadian rhythm for ACTH was established, with a predominance of diurnal values at Tocachi,  More>>
Authors:
Publication Date:
Aug 01, 1975
Product Type:
Technical Report
Report Number:
IAEA-R-1010-F
Reference Number:
AIX-07-242368; EDB-76-072323
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ACTH; RADIOIMMUNOASSAY; TSH; BLOOD PLASMA; DAILY VARIATIONS; DIET; ECUADOR; HUMAN POPULATIONS; IODINE 125; IODINE 131; LEVELS; NUTRITIONAL DEFICIENCY; PROTEINS; TRACER TECHNIQUES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BODY FLUIDS; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; HORMONES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PITUITARY HORMONES; POPULATIONS; RADIOASSAY; RADIOISOTOPES; SOUTH AMERICA; VARIATIONS; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7181978
Research Organizations:
International Atomic Energy Agency, Vienna (Austria)
Country of Origin:
IAEA
Language:
Spanish
Availability:
INIS
Submitting Site:
INIS
Size:
Pages: v
Announcement Date:
May 13, 2001

Technical Report:

Citation Formats

Ramirez, I. Radioisotope studies of steroid hormone levels of plasma in indigenous subjects living at high altitude and submitted to a low calorie diet. Final report for the period of 1 April 1971--30 June 1975. IAEA: N. p., 1975. Web.
Ramirez, I. Radioisotope studies of steroid hormone levels of plasma in indigenous subjects living at high altitude and submitted to a low calorie diet. Final report for the period of 1 April 1971--30 June 1975. IAEA.
Ramirez, I. 1975. "Radioisotope studies of steroid hormone levels of plasma in indigenous subjects living at high altitude and submitted to a low calorie diet. Final report for the period of 1 April 1971--30 June 1975." IAEA.
@misc{etde_7181978,
title = {Radioisotope studies of steroid hormone levels of plasma in indigenous subjects living at high altitude and submitted to a low calorie diet. Final report for the period of 1 April 1971--30 June 1975}
author = {Ramirez, I}
abstractNote = {Radioimmunological techniques were applied to the evaluation of TSH and ACTH in the four groups of Ecuadorian subjects under investigation at Tocachi, Malchingui, Quito and Portoviejo, the first three populations living at a high altitude and the fourth at sea-level. This evaluation was of interest since previous studies had indicated that there were thyroid and adrenal hormone deficiency levels in individuals from Tocachi and Malchingui or, in other words, in populations from a high-altitude region, and also endemic goitre and caloric-protein malnutrition. Furthermore, the Tocachi group was composed of subjects suffering from chronic ''stress''. Parallel to the analysis of TSH and pituitary ACTH levels, the circadian rhythm in the production of these hormones in these subjects was studied. The basal values of TSH and ACHT for the studied groups were found to lie within the normal range. /sup 131/I-TSH and /sup 125/I-ACTH were used. As far as the nycthemeral TSH rhythm is concerned, the values tended to be lowest for the high-altitude populations, while for the groups living at sea-level, where there is also circadian variation, the higher values are found in the morning. Similarly, the circadian rhythm for ACTH was established, with a predominance of diurnal values at Tocachi, Malchingui and Portoviejo.}
place = {IAEA}
year = {1975}
month = {Aug}
}