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Radioreceptor assay for somatomedin A

Journal Article:

Abstract

Measurement method of somatomedian A by radioreceptor assay using the human placenta membrane was described and discussed. Binding rate of /sup 125/I-somatomedin A to its receptors was studied under various conditions of time and temperature of the incubation, and pH of the system. The influence of somatomedin A, porcine insulin, and porcine calcitonin, on /sup 125/I-somatomedin A bound receptors was studied, and these hormones showed the competitive binding to somatomedin A receptors in some level. The specificity, recovery rate, and clinical applications of somatomedin A were also discussed. Radioreceptor assay for somatomedine A provided easier, faster, and more accurate measurements than conventional bioassay. This technique would be very useful to study somatomedin A receptor and functions of insulin.
Authors:
Takano, K [1] 
  1. Tokyo Women's Medical Coll. (Japan)
Publication Date:
Apr 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-244457; EDB-76-076733
Resource Relation:
Journal Name: Saishin Igaku; (Japan); Journal Volume: 30:4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; STH; RADIOASSAY; CELL MEMBRANES; CHEMORECEPTORS; INSULIN; IODINE 125; LABELLED COMPOUNDS; MAN; MEDICAL SUPPLIES; PH VALUE; PLACENTA; SENSITIVITY; STIMULATION; ANIMALS; BETA DECAY RADIOISOTOPES; CELL CONSTITUENTS; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; FETAL MEMBRANES; HORMONES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; MAMMALS; MEMBRANES; NUCLEI; ODD-EVEN NUCLEI; PEPTIDE HORMONES; PITUITARY HORMONES; PRIMATES; RADIOISOTOPES; VERTEBRATES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7179203
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: SAIGA
Submitting Site:
INIS
Size:
Pages: 607-611
Announcement Date:

Journal Article:

Citation Formats

Takano, K. Radioreceptor assay for somatomedin A. Japan: N. p., 1975. Web.
Takano, K. Radioreceptor assay for somatomedin A. Japan.
Takano, K. 1975. "Radioreceptor assay for somatomedin A." Japan.
@misc{etde_7179203,
title = {Radioreceptor assay for somatomedin A}
author = {Takano, K}
abstractNote = {Measurement method of somatomedian A by radioreceptor assay using the human placenta membrane was described and discussed. Binding rate of /sup 125/I-somatomedin A to its receptors was studied under various conditions of time and temperature of the incubation, and pH of the system. The influence of somatomedin A, porcine insulin, and porcine calcitonin, on /sup 125/I-somatomedin A bound receptors was studied, and these hormones showed the competitive binding to somatomedin A receptors in some level. The specificity, recovery rate, and clinical applications of somatomedin A were also discussed. Radioreceptor assay for somatomedine A provided easier, faster, and more accurate measurements than conventional bioassay. This technique would be very useful to study somatomedin A receptor and functions of insulin.}
journal = {Saishin Igaku; (Japan)}
volume = {30:4}
journal type = {AC}
place = {Japan}
year = {1975}
month = {Apr}
}