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/sup 86/Rb uptake of various organs of the spontaneously hypertensive rats

Abstract

Twenty spontaneously hypertensive rats (SHR) and 20 control rats were used for the measurement of Rb/sup 86/ uptake by various organs. Hemodynamic measurements, and the heart weight to body weight ratio showed a significant and sustained hypertension with an increased heart rate in SHR. The ratio of the Rb/sup 86/ uptake in the kidney, brain, liver, adrenal gland, pancreas, and spleen to that in the right ventricle (RV) was smaller in SHR than it was in the control rats. The ratio of the Rb/sup 86/ uptake of the inner layer to the outer layer of the left ventricle (LV), which represents distribution of blood flow to the endocardial layer and epicardial layer, showed no difference between SHR and the control rats. The regional flow fraction in the outer and inner cortex, juxtamedulla, and medulla of the kidney showed no difference between SHR and the control. The present preliminary study suggests that the myocardial blood flow in SHR is greater than that in the control rats. The relationship between cardiac hypertrophy and myocardial flow was discussed.
Authors:
Nakamura, M; Kuroiwa, A; Nakagaki, O; Tomoike, H; Nose, Y [1] 
  1. Kyushu Univ., Fukuoka (Japan). Faculty of Medicine
Publication Date:
Mar 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-244487; EDB-76-077059
Resource Relation:
Journal Name: Jpn. Heart J.; (Japan); Journal Volume: 16:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; RATS; RADIONUCLIDE KINETICS; RUBIDIUM 86; UPTAKE; ADRENAL GLANDS; BLOOD CIRCULATION; BLOOD FLOW; BRAIN; HEART; HYPERTENSION; INTRAVENOUS INJECTION; KIDNEYS; LIVER; PANCREAS; SPLEEN; TRACER TECHNIQUES; WEIGHT; ALKALI METAL ISOTOPES; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; DAYS LIVING RADIOISOTOPES; DIGESTIVE SYSTEM; DISEASES; ENDOCRINE GLANDS; GLANDS; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; MINUTES LIVING RADIOISOTOPES; NERVOUS SYSTEM; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIOISOTOPES; RODENTS; RUBIDIUM ISOTOPES; SYMPTOMS; VASCULAR DISEASES; VERTEBRATES; 560172* - Radiation Effects- Nuclide Kinetics & Toxicology- Animals- (-1987)
OSTI ID:
7178968
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JHEJA
Submitting Site:
INIS
Size:
Pages: 156-161
Announcement Date:
Jul 01, 1976

Citation Formats

Nakamura, M, Kuroiwa, A, Nakagaki, O, Tomoike, H, and Nose, Y. /sup 86/Rb uptake of various organs of the spontaneously hypertensive rats. Japan: N. p., 1975. Web.
Nakamura, M, Kuroiwa, A, Nakagaki, O, Tomoike, H, & Nose, Y. /sup 86/Rb uptake of various organs of the spontaneously hypertensive rats. Japan.
Nakamura, M, Kuroiwa, A, Nakagaki, O, Tomoike, H, and Nose, Y. 1975. "/sup 86/Rb uptake of various organs of the spontaneously hypertensive rats." Japan.
@misc{etde_7178968,
title = {/sup 86/Rb uptake of various organs of the spontaneously hypertensive rats}
author = {Nakamura, M, Kuroiwa, A, Nakagaki, O, Tomoike, H, and Nose, Y}
abstractNote = {Twenty spontaneously hypertensive rats (SHR) and 20 control rats were used for the measurement of Rb/sup 86/ uptake by various organs. Hemodynamic measurements, and the heart weight to body weight ratio showed a significant and sustained hypertension with an increased heart rate in SHR. The ratio of the Rb/sup 86/ uptake in the kidney, brain, liver, adrenal gland, pancreas, and spleen to that in the right ventricle (RV) was smaller in SHR than it was in the control rats. The ratio of the Rb/sup 86/ uptake of the inner layer to the outer layer of the left ventricle (LV), which represents distribution of blood flow to the endocardial layer and epicardial layer, showed no difference between SHR and the control rats. The regional flow fraction in the outer and inner cortex, juxtamedulla, and medulla of the kidney showed no difference between SHR and the control. The present preliminary study suggests that the myocardial blood flow in SHR is greater than that in the control rats. The relationship between cardiac hypertrophy and myocardial flow was discussed.}
journal = []
volume = {16:2}
journal type = {AC}
place = {Japan}
year = {1975}
month = {Mar}
}