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Nhe I and Hinc II polymorphisms in the human laminin B1 chain gene on 7q22

Abstract

pHL-40 and pHL-42 are overlapping cDNA clones that code for 4.2 kb of the 3{prime} end of the 5.5 kb mRNA. Nhe I detects a two allele polymorphism with fragments of 4.3 kb or 4.0 kb and an invariant band of 10.0 kb. Hinc II detects a two allele polymorphism with fragments of 6.6 kb or 5.5 kb and 1.1 kb and invariant bands of 7.8 kb, 4.0 kb, 3.3 kb, 2.3 kb and 0.6 kb. The allele frequency was studied in 60 chromosomes of unrelated Finnish individuals. The probe was localized to chromosome 7q22 by somatic cell and in situ hybridization. Co-dominant inheritance of the Nhe I RFLP was shown in one family and of the Hinc II RFLP in five families.
Authors:
Pikkarainen, T; Savolainen, E R; Tryggvason, K [1] 
  1. Univ. of Oulu (Finland)
Publication Date:
Jun 12, 1989
Product Type:
Journal Article
Reference Number:
EDB-90-055998
Resource Relation:
Journal Name: Nucleic Acids Research; (UK); Journal Volume: 17:11
Subject:
59 BASIC BIOLOGICAL SCIENCES; PROTEINS; MOLECULAR STRUCTURE; RECOMBINANT DNA; DNA SEQUENCING; RFLPS; GENETIC MAPPING; FINLAND; GENES; HETEROCHROMOSOMES; HUMAN POPULATIONS; CHROMOSOMES; DNA; EUROPE; MAPPING; NUCLEIC ACIDS; ORGANIC COMPOUNDS; POPULATIONS; SCANDINAVIA; STRUCTURAL CHEMICAL ANALYSIS; WESTERN EUROPE; 550200* - Biochemistry
OSTI ID:
7168479
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0305-1048; CODEN: NARHA
Submitting Site:
JMT
Size:
Pages: 4424
Announcement Date:
Apr 15, 1990

Citation Formats

Pikkarainen, T, Savolainen, E R, and Tryggvason, K. Nhe I and Hinc II polymorphisms in the human laminin B1 chain gene on 7q22. United Kingdom: N. p., 1989. Web. doi:10.1093/nar/17.11.4424.
Pikkarainen, T, Savolainen, E R, & Tryggvason, K. Nhe I and Hinc II polymorphisms in the human laminin B1 chain gene on 7q22. United Kingdom. https://doi.org/10.1093/nar/17.11.4424
Pikkarainen, T, Savolainen, E R, and Tryggvason, K. 1989. "Nhe I and Hinc II polymorphisms in the human laminin B1 chain gene on 7q22." United Kingdom. https://doi.org/10.1093/nar/17.11.4424.
@misc{etde_7168479,
title = {Nhe I and Hinc II polymorphisms in the human laminin B1 chain gene on 7q22}
author = {Pikkarainen, T, Savolainen, E R, and Tryggvason, K}
abstractNote = {pHL-40 and pHL-42 are overlapping cDNA clones that code for 4.2 kb of the 3{prime} end of the 5.5 kb mRNA. Nhe I detects a two allele polymorphism with fragments of 4.3 kb or 4.0 kb and an invariant band of 10.0 kb. Hinc II detects a two allele polymorphism with fragments of 6.6 kb or 5.5 kb and 1.1 kb and invariant bands of 7.8 kb, 4.0 kb, 3.3 kb, 2.3 kb and 0.6 kb. The allele frequency was studied in 60 chromosomes of unrelated Finnish individuals. The probe was localized to chromosome 7q22 by somatic cell and in situ hybridization. Co-dominant inheritance of the Nhe I RFLP was shown in one family and of the Hinc II RFLP in five families.}
doi = {10.1093/nar/17.11.4424}
journal = []
volume = {17:11}
journal type = {AC}
place = {United Kingdom}
year = {1989}
month = {Jun}
}