Abstract
A 700 bp fragment of the cDNA clone for the human cytochrome P450 gene cloned in pUC9 at the PstI restriction site. XmnI detects a two allele polymorphism with bands at 10.00 kb (A1), 4.8 kb (A2) and constants bands at 13.0, 8.3, 4.6, 3.1, 2.8, 2.5, 2.3, 2.2, 1.8 and 1.5 kb. A total of 16 unrelated individuals of Caucasian origin were screened for A1 (.625) and A2 (.375). The probe was assigned to chromosome 10q24.1-q24.3 using a panel of human-rodent somatic cell hybrids and in situ hybridization. Co-dominant inheritance was observed in 3 families from CEPH, K1329 2 K1331 and K1333.
Gough, A C;
Spurr, N K;
[1]
Meehan, R R;
Miles, J S;
Wolf, C R
[2]
- Clare Hall Laboratories, Herts (England)
- Univ. Department of Biochemistry, Edinburgh (England)
Citation Formats
Gough, A C, Spurr, N K, Meehan, R R, Miles, J S, and Wolf, C R.
An XmnI RFLP detected with a cDNA probe for the CYP2C gene locus on chromosome 10.
United Kingdom: N. p.,
1989.
Web.
doi:10.1093/nar/17.11.4426.
Gough, A C, Spurr, N K, Meehan, R R, Miles, J S, & Wolf, C R.
An XmnI RFLP detected with a cDNA probe for the CYP2C gene locus on chromosome 10.
United Kingdom.
https://doi.org/10.1093/nar/17.11.4426
Gough, A C, Spurr, N K, Meehan, R R, Miles, J S, and Wolf, C R.
1989.
"An XmnI RFLP detected with a cDNA probe for the CYP2C gene locus on chromosome 10."
United Kingdom.
https://doi.org/10.1093/nar/17.11.4426.
@misc{etde_7168478,
title = {An XmnI RFLP detected with a cDNA probe for the CYP2C gene locus on chromosome 10}
author = {Gough, A C, Spurr, N K, Meehan, R R, Miles, J S, and Wolf, C R}
abstractNote = {A 700 bp fragment of the cDNA clone for the human cytochrome P450 gene cloned in pUC9 at the PstI restriction site. XmnI detects a two allele polymorphism with bands at 10.00 kb (A1), 4.8 kb (A2) and constants bands at 13.0, 8.3, 4.6, 3.1, 2.8, 2.5, 2.3, 2.2, 1.8 and 1.5 kb. A total of 16 unrelated individuals of Caucasian origin were screened for A1 (.625) and A2 (.375). The probe was assigned to chromosome 10q24.1-q24.3 using a panel of human-rodent somatic cell hybrids and in situ hybridization. Co-dominant inheritance was observed in 3 families from CEPH, K1329 2 K1331 and K1333.}
doi = {10.1093/nar/17.11.4426}
journal = []
volume = {17:11}
journal type = {AC}
place = {United Kingdom}
year = {1989}
month = {Jun}
}
title = {An XmnI RFLP detected with a cDNA probe for the CYP2C gene locus on chromosome 10}
author = {Gough, A C, Spurr, N K, Meehan, R R, Miles, J S, and Wolf, C R}
abstractNote = {A 700 bp fragment of the cDNA clone for the human cytochrome P450 gene cloned in pUC9 at the PstI restriction site. XmnI detects a two allele polymorphism with bands at 10.00 kb (A1), 4.8 kb (A2) and constants bands at 13.0, 8.3, 4.6, 3.1, 2.8, 2.5, 2.3, 2.2, 1.8 and 1.5 kb. A total of 16 unrelated individuals of Caucasian origin were screened for A1 (.625) and A2 (.375). The probe was assigned to chromosome 10q24.1-q24.3 using a panel of human-rodent somatic cell hybrids and in situ hybridization. Co-dominant inheritance was observed in 3 families from CEPH, K1329 2 K1331 and K1333.}
doi = {10.1093/nar/17.11.4426}
journal = []
volume = {17:11}
journal type = {AC}
place = {United Kingdom}
year = {1989}
month = {Jun}
}