Abstract
A myeloperoxidase (MPO) cDNA clone (pHMP7: 270 base pair insert in the vector pGEM-1reverse arrow was isolated from a library created from human promyelocytic (HL-60) cell mRNA. PstI (CTGCA/G) (New England Biolabs) identifies a simple two-allele polymorphism with bands at either 2.2 kb (Al) or 2.0 kb (A2). There are three constant bands at 2.8 kb, 0.95 kb and 0.6 kb. Preliminary family data show evidence of linkage to several markers in proximal 17q, with MPO closest to the Growth Hormone cluster at 17q22-q24. Autosomal condominant segregation was observed in four large reference pedigrees with several informative matings.
Citation Formats
Miki, T, Weil, S C, Rosner, G L, Reid, M S, and Kidd, K K.
MPO cDNA clone identifies an RFLP with PstI.
United Kingdom: N. p.,
1988.
Web.
doi:10.1093/nar/16.4.1649.
Miki, T, Weil, S C, Rosner, G L, Reid, M S, & Kidd, K K.
MPO cDNA clone identifies an RFLP with PstI.
United Kingdom.
https://doi.org/10.1093/nar/16.4.1649
Miki, T, Weil, S C, Rosner, G L, Reid, M S, and Kidd, K K.
1988.
"MPO cDNA clone identifies an RFLP with PstI."
United Kingdom.
https://doi.org/10.1093/nar/16.4.1649.
@misc{etde_7164763,
title = {MPO cDNA clone identifies an RFLP with PstI}
author = {Miki, T, Weil, S C, Rosner, G L, Reid, M S, and Kidd, K K}
abstractNote = {A myeloperoxidase (MPO) cDNA clone (pHMP7: 270 base pair insert in the vector pGEM-1reverse arrow was isolated from a library created from human promyelocytic (HL-60) cell mRNA. PstI (CTGCA/G) (New England Biolabs) identifies a simple two-allele polymorphism with bands at either 2.2 kb (Al) or 2.0 kb (A2). There are three constant bands at 2.8 kb, 0.95 kb and 0.6 kb. Preliminary family data show evidence of linkage to several markers in proximal 17q, with MPO closest to the Growth Hormone cluster at 17q22-q24. Autosomal condominant segregation was observed in four large reference pedigrees with several informative matings.}
doi = {10.1093/nar/16.4.1649}
journal = []
volume = {16:4}
journal type = {AC}
place = {United Kingdom}
year = {1988}
month = {Feb}
}
title = {MPO cDNA clone identifies an RFLP with PstI}
author = {Miki, T, Weil, S C, Rosner, G L, Reid, M S, and Kidd, K K}
abstractNote = {A myeloperoxidase (MPO) cDNA clone (pHMP7: 270 base pair insert in the vector pGEM-1reverse arrow was isolated from a library created from human promyelocytic (HL-60) cell mRNA. PstI (CTGCA/G) (New England Biolabs) identifies a simple two-allele polymorphism with bands at either 2.2 kb (Al) or 2.0 kb (A2). There are three constant bands at 2.8 kb, 0.95 kb and 0.6 kb. Preliminary family data show evidence of linkage to several markers in proximal 17q, with MPO closest to the Growth Hormone cluster at 17q22-q24. Autosomal condominant segregation was observed in four large reference pedigrees with several informative matings.}
doi = {10.1093/nar/16.4.1649}
journal = []
volume = {16:4}
journal type = {AC}
place = {United Kingdom}
year = {1988}
month = {Feb}
}