You need JavaScript to view this

Correlation between radiosensitivity of transplanted solid tumor and nutritive condition of host animal

Journal Article:

Abstract

Studies on radiosensitivity of the transplanted tumor were carried out and the following results were obtained: 1. Radiosensitivity of the tumor ran parallel to the growth rate. 2. Malnutrition of the host after irradiation made the tumor radiosensitive, probably because the sublethally damaged tumor cell did not recover. 3. Mitotic index correlated well with radiosensitivity, and the low mitotic index caused by starvation made the tumor cell recover poorly. 4. The DNA synthetic rate measured by means of iodine labeled IUdR did not successfully correlate with the mitotic rate, presumably because of the role of thymidine pool size in this experiment. 5. The serum protein level possibly with the tumor growth, which modified the radiosensitivity. 6. Serum oxygen was difficult to interpret, however, it might be compensated by erythrocytosis in a starved condition.
Authors:
Ando, K [1] 
  1. Showa Univ., Tokyo (Japan). School of Medicine
Publication Date:
Apr 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-268356; EDB-77-008944
Resource Relation:
Journal Name: Showa Igakkai Zasshi; (Japan); Journal Volume: 35:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; TUMOR CELLS; RADIOSENSITIVITY; BIOLOGICAL RADIATION EFFECTS; BIOSYNTHESIS; BLOOD; DNA; EXPERIMENTAL NEOPLASMS; FASTING; GROWTH; MITOTIC INDEX; NUTRITION; RADIATION DOSES; RATS; TIME DEPENDENCE; X RADIATION; ANIMAL CELLS; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BODY FLUIDS; DISEASES; DOSES; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; MAMMALS; NEOPLASMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATION EFFECTS; RADIATIONS; RODENTS; SYNTHESIS; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
7141466
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: SIGZA
Submitting Site:
INIS
Size:
Pages: 145-151
Announcement Date:
Nov 01, 1976

Journal Article:

Citation Formats

Ando, K. Correlation between radiosensitivity of transplanted solid tumor and nutritive condition of host animal. Japan: N. p., 1975. Web.
Ando, K. Correlation between radiosensitivity of transplanted solid tumor and nutritive condition of host animal. Japan.
Ando, K. 1975. "Correlation between radiosensitivity of transplanted solid tumor and nutritive condition of host animal." Japan.
@misc{etde_7141466,
title = {Correlation between radiosensitivity of transplanted solid tumor and nutritive condition of host animal}
author = {Ando, K}
abstractNote = {Studies on radiosensitivity of the transplanted tumor were carried out and the following results were obtained: 1. Radiosensitivity of the tumor ran parallel to the growth rate. 2. Malnutrition of the host after irradiation made the tumor radiosensitive, probably because the sublethally damaged tumor cell did not recover. 3. Mitotic index correlated well with radiosensitivity, and the low mitotic index caused by starvation made the tumor cell recover poorly. 4. The DNA synthetic rate measured by means of iodine labeled IUdR did not successfully correlate with the mitotic rate, presumably because of the role of thymidine pool size in this experiment. 5. The serum protein level possibly with the tumor growth, which modified the radiosensitivity. 6. Serum oxygen was difficult to interpret, however, it might be compensated by erythrocytosis in a starved condition.}
journal = {Showa Igakkai Zasshi; (Japan)}
volume = {35:2}
journal type = {AC}
place = {Japan}
year = {1975}
month = {Apr}
}