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Changes in protein metabolism after irradiation. Pt. 2. Protease activity, protease pattern, protein and free amino acids in cytoplasm and cell organelles of the rat liver after 600 R whole body X-irradiation

Journal Article:

Abstract

The protease activity of cytoplasm and cell organelles of the rat liver against liver protein and hemoglobin as a substrate increases during an initial reaction phase on the first day after 600 R whole body x irradiation. This is probably a consequence of the degradation of cellular debris. The protein, the protease activity and the free amino acids of the cytoplasm and the cell organelles decrease during the disease phase on day 3 and 4 after irradiation. The protein loss of the liver is therefore not explained by an increased protease activity. The protease activity and the free amino acids are increased in the cytoplasm and the cell organelles during the regeneration phase of the organism between day 15 and 18 after irradiation.
Authors:
Valet, G [1] 
  1. Max-Planck-Institut fuer Biochemie, Muenchen (F.R. Germany). Abt. fuer Experimentelle Medizin
Publication Date:
Jan 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-07-257471; EDB-77-008954
Resource Relation:
Journal Name: Strahlentherapie; (Germany, Federal Republic of); Journal Volume: 151:1; Other Information: 4 figs.; 4 tabs.; 16 refs
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; PEPTIDE HYDROLASES; BIOLOGICAL RADIATION EFFECTS; PROTEINS; METABOLISM; AMINO ACIDS; ANIMAL CELLS; BIOLOGICAL REGENERATION; CELL CONSTITUENTS; CYTOPLASM; LIVER; RATS; TIME DEPENDENCE; WHOLE-BODY IRRADIATION; X RADIATION; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; BODY; CARBOXYLIC ACIDS; DIGESTIVE SYSTEM; ELECTROMAGNETIC RADIATION; ENZYMES; EXTERNAL IRRADIATION; GLANDS; HYDROLASES; IONIZING RADIATIONS; IRRADIATION; MAMMALS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIATION EFFECTS; RADIATIONS; RECOVERY; RODENTS; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
7141458
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: STRAA
Submitting Site:
INIS
Size:
Pages: 61-68
Announcement Date:
Sep 01, 1976

Journal Article:

Citation Formats

Valet, G. Changes in protein metabolism after irradiation. Pt. 2. Protease activity, protease pattern, protein and free amino acids in cytoplasm and cell organelles of the rat liver after 600 R whole body X-irradiation. Germany: N. p., 1976. Web.
Valet, G. Changes in protein metabolism after irradiation. Pt. 2. Protease activity, protease pattern, protein and free amino acids in cytoplasm and cell organelles of the rat liver after 600 R whole body X-irradiation. Germany.
Valet, G. 1976. "Changes in protein metabolism after irradiation. Pt. 2. Protease activity, protease pattern, protein and free amino acids in cytoplasm and cell organelles of the rat liver after 600 R whole body X-irradiation." Germany.
@misc{etde_7141458,
title = {Changes in protein metabolism after irradiation. Pt. 2. Protease activity, protease pattern, protein and free amino acids in cytoplasm and cell organelles of the rat liver after 600 R whole body X-irradiation}
author = {Valet, G}
abstractNote = {The protease activity of cytoplasm and cell organelles of the rat liver against liver protein and hemoglobin as a substrate increases during an initial reaction phase on the first day after 600 R whole body x irradiation. This is probably a consequence of the degradation of cellular debris. The protein, the protease activity and the free amino acids of the cytoplasm and the cell organelles decrease during the disease phase on day 3 and 4 after irradiation. The protein loss of the liver is therefore not explained by an increased protease activity. The protease activity and the free amino acids are increased in the cytoplasm and the cell organelles during the regeneration phase of the organism between day 15 and 18 after irradiation.}
journal = {Strahlentherapie; (Germany, Federal Republic of)}
volume = {151:1}
journal type = {AC}
place = {Germany}
year = {1976}
month = {Jan}
}