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Radiotherapy and pulmonary fibrosis

Journal Article:

Abstract

Clinical findings of radiation pneumonitis and pulmonary fibrosis were outlined, and the relationship between occurence of these disorders and radiotherapy, clinical findings and X-ray picture were studied. Standard radiation dose as cell lethal response of carcinoma of the lung were 4,500 to 5,500 rad in 4 to 5.5 weeks in undifferentiated carcinoma, 6,000 to 7,000 rad in 6 to 7 weeks in squamous cell carcinoma, 7,000 to 9,000 rad in 7 to 9 weeks in adenocarcinoma, 4,500 to 5,000 rad in 4 to 5 weeks in the large sized cancer of the esophagus, 6,500 to 7,000 rad in 5 to 7 weeks in the small sized cancer of the esophagus, and irradiation of these amount of dose caused hazards in pulmonary function. Pathological and clinical findings of pulmonary hazards within 6 month period after irradiation, factors causing them and changes in X-ray pictures before and after irradiation were observed and discussed in clinical cases: the case of breast cancer in which 3,000 R/6 times/18 days of 5.5 MeV Liniac electron was irradiated to the chest wall, and the case of pulmonary cancer in which 5,000 rad/25 times/34 days of 6 MeV Liniac X-ray was irradiated in opposite 2 ports radiation  More>>
Authors:
Sone, S; Miyata, Y; Tachiiri, H [1] 
  1. Osaka Univ. (Japan). Faculty of Medicine
Publication Date:
Apr 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-260179; EDB-77-014596
Resource Relation:
Journal Name: Shindan To Chiryo; (Japan); Journal Volume: 63:4
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; FIBROSIS; RADIOINDUCTION; LUNGS; BIOLOGICAL RADIATION EFFECTS; RADIOTHERAPY; SIDE EFFECTS; BIOMEDICAL RADIOGRAPHY; NEOPLASMS; PATIENTS; RADIATION DOSES; RESPIRATORY SYSTEM DISEASES; BIOLOGICAL EFFECTS; BODY; DIAGNOSTIC TECHNIQUES; DISEASES; DOSES; MEDICINE; NUCLEAR MEDICINE; ORGANS; PATHOLOGICAL CHANGES; RADIATION EFFECTS; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY; 560151* - Radiation Effects on Animals- Man
OSTI ID:
7139593
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: SHCHA
Submitting Site:
INIS
Size:
Pages: 605-611
Announcement Date:
Oct 01, 1976

Journal Article:

Citation Formats

Sone, S, Miyata, Y, and Tachiiri, H. Radiotherapy and pulmonary fibrosis. Japan: N. p., 1975. Web.
Sone, S, Miyata, Y, & Tachiiri, H. Radiotherapy and pulmonary fibrosis. Japan.
Sone, S, Miyata, Y, and Tachiiri, H. 1975. "Radiotherapy and pulmonary fibrosis." Japan.
@misc{etde_7139593,
title = {Radiotherapy and pulmonary fibrosis}
author = {Sone, S, Miyata, Y, and Tachiiri, H}
abstractNote = {Clinical findings of radiation pneumonitis and pulmonary fibrosis were outlined, and the relationship between occurence of these disorders and radiotherapy, clinical findings and X-ray picture were studied. Standard radiation dose as cell lethal response of carcinoma of the lung were 4,500 to 5,500 rad in 4 to 5.5 weeks in undifferentiated carcinoma, 6,000 to 7,000 rad in 6 to 7 weeks in squamous cell carcinoma, 7,000 to 9,000 rad in 7 to 9 weeks in adenocarcinoma, 4,500 to 5,000 rad in 4 to 5 weeks in the large sized cancer of the esophagus, 6,500 to 7,000 rad in 5 to 7 weeks in the small sized cancer of the esophagus, and irradiation of these amount of dose caused hazards in pulmonary function. Pathological and clinical findings of pulmonary hazards within 6 month period after irradiation, factors causing them and changes in X-ray pictures before and after irradiation were observed and discussed in clinical cases: the case of breast cancer in which 3,000 R/6 times/18 days of 5.5 MeV Liniac electron was irradiated to the chest wall, and the case of pulmonary cancer in which 5,000 rad/25 times/34 days of 6 MeV Liniac X-ray was irradiated in opposite 2 ports radiation beam treatment. The former revealed alveolar lesion and interlobular pleuritis at 4 month later, and remarkable lesion of pulmonary fibrosis was followed at 9 month after radiotherapy. The later developed radiation pneumonitis 1 month after radiotherapy, of which lesion extended to the upper part by 3 months later, and cancer recurred 6.5 month later.}
journal = {Shindan To Chiryo; (Japan)}
volume = {63:4}
journal type = {AC}
place = {Japan}
year = {1975}
month = {Apr}
}