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Relationship between accumulation of rare earth element in tumor and ionic radius

Abstract

The accumulation of rare earth elements in the different organs of Ehrlich's tumor-bearing mice at 48 hours after intraperitoneal administration was measured by a Ge(Li) semiconductor detector. Accumulation of all the rare earth elements was the highest in the pancreas. Accumulation of /sup 152/Eu in the different organs of Ehrlich's tumor-bearing mice was very high. The accumulation of rare earth elements in Ehrlich's tumor was lower than the accumulation of /sup 67/Ga and /sup 46/Sc. The tumor-organ concentration ratio of rare earth elements was remarkably lower than the accumulation of /sup 67/Ga and /sup 46/Sc. However, the accumulation of /sup 152/Eu in Ehrlich's tumor was somewhat higher than that of /sup 67/Ga. The relationship between the accumulation and the carrier content was examined. The lower the carrier content was, the higher was the accumulation in different organs. However, the carrier effect of rare earth on the uptake in different organs elements was slight. The author postulated that the elements in which the ionic radius is similar to that of Mg(0.62 A) or Ca(0.99 A) are abundant in the tumor cell membrane, and they might pass through the tumor cell membrane much more easily than would the other elements. However, the  More>>
Authors:
Kataoka, N [1] 
  1. Kanazawa Univ. (Japan). School of Medicine
Publication Date:
Feb 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-07-260269; EDB-77-014732
Resource Relation:
Journal Name: Kanazawa Irigaku Sosho; (Japan); Journal Volume: 98
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; EUROPIUM 152; UPTAKE; GADOLINIUM 159; HOLMIUM 166; LUTETIUM 177; MICE; RADIONUCLIDE KINETICS; SAMARIUM 153; TERBIUM 160; YTTERBIUM 169; AFFINITY; CARRIERS; CHEMICAL PROPERTIES; COMPARATIVE EVALUATIONS; EHRLICH ASCITES TUMOR; KIDNEYS; LIVER; PANCREAS; SPLEEN; THYMUS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; DAYS LIVING RADIOISOTOPES; DIGESTIVE SYSTEM; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; ENDOCRINE GLANDS; EUROPIUM ISOTOPES; EVEN-ODD NUCLEI; EXPERIMENTAL NEOPLASMS; GADOLINIUM ISOTOPES; GLANDS; HOLMIUM ISOTOPES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LUTETIUM ISOTOPES; LYMPHATIC SYSTEM; MAMMALS; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIOISOTOPES; RARE EARTH ISOTOPES; RARE EARTH NUCLEI; RODENTS; SAMARIUM ISOTOPES; SECONDS LIVING RADIOISOTOPES; TERBIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES; YTTERBIUM ISOTOPES; 560172* - Radiation Effects- Nuclide Kinetics & Toxicology- Animals- (-1987)
OSTI ID:
7139530
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: KISOA
Submitting Site:
INIS
Size:
Pages: 65-82
Announcement Date:
Oct 01, 1976

Citation Formats

Kataoka, N. Relationship between accumulation of rare earth element in tumor and ionic radius. Japan: N. p., 1975. Web.
Kataoka, N. Relationship between accumulation of rare earth element in tumor and ionic radius. Japan.
Kataoka, N. 1975. "Relationship between accumulation of rare earth element in tumor and ionic radius." Japan.
@misc{etde_7139530,
title = {Relationship between accumulation of rare earth element in tumor and ionic radius}
author = {Kataoka, N}
abstractNote = {The accumulation of rare earth elements in the different organs of Ehrlich's tumor-bearing mice at 48 hours after intraperitoneal administration was measured by a Ge(Li) semiconductor detector. Accumulation of all the rare earth elements was the highest in the pancreas. Accumulation of /sup 152/Eu in the different organs of Ehrlich's tumor-bearing mice was very high. The accumulation of rare earth elements in Ehrlich's tumor was lower than the accumulation of /sup 67/Ga and /sup 46/Sc. The tumor-organ concentration ratio of rare earth elements was remarkably lower than the accumulation of /sup 67/Ga and /sup 46/Sc. However, the accumulation of /sup 152/Eu in Ehrlich's tumor was somewhat higher than that of /sup 67/Ga. The relationship between the accumulation and the carrier content was examined. The lower the carrier content was, the higher was the accumulation in different organs. However, the carrier effect of rare earth on the uptake in different organs elements was slight. The author postulated that the elements in which the ionic radius is similar to that of Mg(0.62 A) or Ca(0.99 A) are abundant in the tumor cell membrane, and they might pass through the tumor cell membrane much more easily than would the other elements. However, the result was negative.}
journal = []
volume = {98}
journal type = {AC}
place = {Japan}
year = {1975}
month = {Feb}
}