You need JavaScript to view this

Distribution of /sup 63/Ni in mice by means of whole body autoradiography

Abstract

The uptake of Ni which was known to be contained in the dental alloy to the mammalian tissue was studied. /sup 63/Ni was injected intravenously to mice, and its distribution in their body was observed by counting radioactivity using whole body autoradiography and liquid scintillation counter from 30 minutes after the injection to 3 weeks later. Whole body autography revealed high uptake in the kidney, lung, incisor, intervertebral disc, epidermis cuticle, hair follicle, and liver during 30 minutes later to 8 hours period, and in the lung, renal cortex, central nerve, epidermis cuticle, and hair follicle during 2 days to 3 weeks period. /sup 63/Ni taken up in the tissue or organs rapidly disappeared by 8 hours period, and the rank of high uptake tissues slightly changed during 30 minutes later to 8 hours period. /sup 63/Ni administered in the body was considered to be excreted through the kidney, however, /sup 63/Ni taken up in the central nerve showed remarkably delayed excretion.
Authors:
Saito, T [1] 
  1. Nihon Univ., Tokyo. School of Dentistry
Publication Date:
Nov 01, 1974
Product Type:
Journal Article
Reference Number:
AIX-07-263010; EDB-77-020548
Resource Relation:
Journal Name: Nichidai Shigaku; (Japan); Journal Volume: 48:6
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; MICE; RADIONUCLIDE KINETICS; NICKEL 63; TISSUE DISTRIBUTION; AUTORADIOGRAPHY; CENTRAL NERVOUS SYSTEM; KIDNEYS; LUNGS; NICKEL COMPOUNDS; RETENTION; SKIN; TEETH; UPTAKE; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; DIGESTIVE SYSTEM; DISTRIBUTION; EVEN-ODD NUCLEI; INTERMEDIATE MASS NUCLEI; ISOTOPES; MAMMALS; NERVOUS SYSTEM; NICKEL ISOTOPES; NUCLEI; ORAL CAVITY; ORGANS; RADIOISOTOPES; RESPIRATORY SYSTEM; RODENTS; TRANSITION ELEMENT COMPOUNDS; VERTEBRATES; YEARS LIVING RADIOISOTOPES; 560172* - Radiation Effects- Nuclide Kinetics & Toxicology- Animals- (-1987)
OSTI ID:
7137336
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: NISHB
Submitting Site:
INIS
Size:
Pages: 707-711
Announcement Date:
Oct 01, 1976

Citation Formats

Saito, T. Distribution of /sup 63/Ni in mice by means of whole body autoradiography. Japan: N. p., 1974. Web.
Saito, T. Distribution of /sup 63/Ni in mice by means of whole body autoradiography. Japan.
Saito, T. 1974. "Distribution of /sup 63/Ni in mice by means of whole body autoradiography." Japan.
@misc{etde_7137336,
title = {Distribution of /sup 63/Ni in mice by means of whole body autoradiography}
author = {Saito, T}
abstractNote = {The uptake of Ni which was known to be contained in the dental alloy to the mammalian tissue was studied. /sup 63/Ni was injected intravenously to mice, and its distribution in their body was observed by counting radioactivity using whole body autoradiography and liquid scintillation counter from 30 minutes after the injection to 3 weeks later. Whole body autography revealed high uptake in the kidney, lung, incisor, intervertebral disc, epidermis cuticle, hair follicle, and liver during 30 minutes later to 8 hours period, and in the lung, renal cortex, central nerve, epidermis cuticle, and hair follicle during 2 days to 3 weeks period. /sup 63/Ni taken up in the tissue or organs rapidly disappeared by 8 hours period, and the rank of high uptake tissues slightly changed during 30 minutes later to 8 hours period. /sup 63/Ni administered in the body was considered to be excreted through the kidney, however, /sup 63/Ni taken up in the central nerve showed remarkably delayed excretion.}
journal = []
volume = {48:6}
journal type = {AC}
place = {Japan}
year = {1974}
month = {Nov}
}