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Indium-111-labelled leucocytes for localisation of abscesses

Abstract

Leucocytes from eight patients who were thought to have an abscess were labelled with indium-111 and reintroduced into the circulation. The distribution of radioactivity was followed by whole-body scanning and imaging with a gamma camera. Focal accumulations of radioactivity were observed in the lesion in the three patients with abscesses, in the lungs of a boy with bacterial endocarditis, in the knee of a woman with rheumatoid arthritis, and at the site of intramuscular injections in another patient. The use of radiolabelled cells for the detection of focal pathological processes would seem to be an important addition to conventional diagnostic methods.
Authors:
Segal, A W; Thakur, M L; Arnot, R N; Lavender, J P [1] 
  1. Royal Postgraduate Medical School, London (UK)
Publication Date:
Nov 13, 1976
Product Type:
Journal Article
Reference Number:
AIX-08-293365; EDB-77-051904
Resource Relation:
Journal Name: Lancet; (United Kingdom); Journal Volume: 2:7994
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ABSCESSES; DIAGNOSIS; INDIUM 111; SCINTISCANNING; BIOLOGICAL LOCALIZATION; INDIUM COMPOUNDS; LABELLING; LEUKOCYTES; PATIENTS; RADIOPHARMACEUTICALS; RHEUMATIC DISEASES; BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; INDIUM ISOTOPES; INFLAMMATION; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-EVEN NUCLEI; PATHOLOGICAL CHANGES; RADIOACTIVE MATERIALS; RADIOISOTOPE SCANNING; RADIOISOTOPES; SKELETAL DISEASES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7126165
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: LANCA
Submitting Site:
INIS
Size:
Pages: 1056-1058
Announcement Date:

Citation Formats

Segal, A W, Thakur, M L, Arnot, R N, and Lavender, J P. Indium-111-labelled leucocytes for localisation of abscesses. United Kingdom: N. p., 1976. Web. doi:10.1016/S0140-6736(76)90969-7.
Segal, A W, Thakur, M L, Arnot, R N, & Lavender, J P. Indium-111-labelled leucocytes for localisation of abscesses. United Kingdom. doi:10.1016/S0140-6736(76)90969-7.
Segal, A W, Thakur, M L, Arnot, R N, and Lavender, J P. 1976. "Indium-111-labelled leucocytes for localisation of abscesses." United Kingdom. doi:10.1016/S0140-6736(76)90969-7. https://www.osti.gov/servlets/purl/10.1016/S0140-6736(76)90969-7.
@misc{etde_7126165,
title = {Indium-111-labelled leucocytes for localisation of abscesses}
author = {Segal, A W, Thakur, M L, Arnot, R N, and Lavender, J P}
abstractNote = {Leucocytes from eight patients who were thought to have an abscess were labelled with indium-111 and reintroduced into the circulation. The distribution of radioactivity was followed by whole-body scanning and imaging with a gamma camera. Focal accumulations of radioactivity were observed in the lesion in the three patients with abscesses, in the lungs of a boy with bacterial endocarditis, in the knee of a woman with rheumatoid arthritis, and at the site of intramuscular injections in another patient. The use of radiolabelled cells for the detection of focal pathological processes would seem to be an important addition to conventional diagnostic methods.}
doi = {10.1016/S0140-6736(76)90969-7}
journal = {Lancet; (United Kingdom)}
volume = {2:7994}
journal type = {AC}
place = {United Kingdom}
year = {1976}
month = {Nov}
}