Individual and collective protection procedures in the handling of significant amounts of plutonium have been adopted for many years; they are founded on its properties. Monitoring and counting techniques make it possible to follow the conditions of these protection procedures seriously. Minor or major failures in protection have never resulted in serious consequences for the public or for workers. Such a result has been obtained thanks to the existence of collective and individual protection procedures, the quality of prevention and the availability of efficient emergency means. The keeping of careful prevention, cooperation of all proficiencies, added to a long standing experience make it possible to state that plutonium handling does not present any more danger than many other (industrial or not) human activities.