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Application of trace element analysis to determine trace element concentrations in the field of medicine. [Neutrons]

Abstract

Applied trace elements research in medicine requires a sensitive and efficient technique of trace elements analysis, such as neutron activation analysis. Essential trace elements act as stabilizators (iron in haem), structural elements (silicon in fibrous tissue), in hormones (iodine in thyroid hormone), in vitamins (cobalt in vitamin B 12), and in enzymes. Most of the essential trace elements act as coenzymes or in coenzymes or directly as metabolic catalyzers. For example, selenium deficiency in PKU and maple syrup patients receiving dietary treatment can be detected by determining the selenium content of the serum, while low selenium values in the whole blood indicate liver cirrhosis. Acrodermatitis enteropathica can be diagnosed by determinig zinc in the serum, and pancreatic insufficiency by determining zinc in the pancreatic juice. Zinc also plays a part in disturbances of growth, in the healing of wounds, and in the insulin metabolism. Cobalt is important in some types of anaemia and in myocardiopathies. Trace elements are also necessary in the treatment of diseases, e.g. iron cobalt in some types of anaemia, and zinc in the delayed healing of wounds in the postoperative phase and in acrodermatitis enteropathica. Chromium is now being tested for the treatment of diabetes mellitus,  More>>
Publication Date:
Jan 01, 1976
Product Type:
Conference
Report Number:
AED-Conf-76-134-050; CONF-760592-53
Reference Number:
AIX-07-264999; EDB-77-094588
Resource Relation:
Conference: 7. scientific meeting of the Deutsche Gesellschaft fuer Medizinische Physik e.V., Heidelberg, F.R. Germany, 5 May 1976; Other Information: 9 figs.; 2 tabs.; 34 refs
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; ACTIVATION ANALYSIS; MEDICINE; BIOLOGICAL MATERIALS; BIOSPHERE; BODY FLUIDS; DIAGNOSIS; DISEASES; DISTRIBUTION; ELEMENTS; METABOLISM; NEUTRON REACTIONS; NUTRITION; REVIEWS; SAMPLE PREPARATION; THERAPY; TISSUES; TRACE AMOUNTS; USES; BARYON REACTIONS; BODY; CHEMICAL ANALYSIS; DOCUMENT TYPES; ENVIRONMENT; HADRON REACTIONS; NUCLEAR REACTIONS; NUCLEON REACTIONS; 400101* - Activation, Nuclear Reaction, Radiometric & Radiochemical Procedures
OSTI ID:
7112999
Research Organizations:
Kernforschungsanlage Juelich G.m.b.H. (Germany, F.R.). Inst. fuer Medizin
Country of Origin:
Germany
Language:
German
Availability:
INIS
Submitting Site:
INIS
Size:
Pages: 28
Announcement Date:

Citation Formats

Kasperek, K, and Feinendegen, L E. Application of trace element analysis to determine trace element concentrations in the field of medicine. [Neutrons]. Germany: N. p., 1976. Web.
Kasperek, K, & Feinendegen, L E. Application of trace element analysis to determine trace element concentrations in the field of medicine. [Neutrons]. Germany.
Kasperek, K, and Feinendegen, L E. 1976. "Application of trace element analysis to determine trace element concentrations in the field of medicine. [Neutrons]." Germany.
@misc{etde_7112999,
title = {Application of trace element analysis to determine trace element concentrations in the field of medicine. [Neutrons]}
author = {Kasperek, K, and Feinendegen, L E}
abstractNote = {Applied trace elements research in medicine requires a sensitive and efficient technique of trace elements analysis, such as neutron activation analysis. Essential trace elements act as stabilizators (iron in haem), structural elements (silicon in fibrous tissue), in hormones (iodine in thyroid hormone), in vitamins (cobalt in vitamin B 12), and in enzymes. Most of the essential trace elements act as coenzymes or in coenzymes or directly as metabolic catalyzers. For example, selenium deficiency in PKU and maple syrup patients receiving dietary treatment can be detected by determining the selenium content of the serum, while low selenium values in the whole blood indicate liver cirrhosis. Acrodermatitis enteropathica can be diagnosed by determinig zinc in the serum, and pancreatic insufficiency by determining zinc in the pancreatic juice. Zinc also plays a part in disturbances of growth, in the healing of wounds, and in the insulin metabolism. Cobalt is important in some types of anaemia and in myocardiopathies. Trace elements are also necessary in the treatment of diseases, e.g. iron cobalt in some types of anaemia, and zinc in the delayed healing of wounds in the postoperative phase and in acrodermatitis enteropathica. Chromium is now being tested for the treatment of diabetes mellitus, and fluorides may be of interest in the treatment of osteoporosis. Finally, trace elements are important in the aetiology of acute poisoning, in nutrition, and in environmental protection.}
place = {Germany}
year = {1976}
month = {Jan}
}