You need JavaScript to view this

Early radiation impairment of the cholesterol metabolism in organelles of rat liver cells

Journal Article:

Abstract

The incorporation of 1-C/sup 14/-acetate into cholesterol of the nuclear, mitochondrial, microsomal and 105000 g-supernatant fractions isolated from the rat liver in norm and 60 min after the exposure to 1200 r has been investigated. An increase has been observed in the label uptake into liver cholesterol of irradiated rats. Intracellular distribution of the newly synthesized (labelled) cholesterol is substantially changed after irradiation: maximum label incorporation into the cholesterol is observed in the 105000 g-supernatant fraction, whereas, normally, the cholesterol of microsomal fraction has the highest specific activity.
Authors:
Kaznacherev, Yu S; Kolomiitseva, I K [1] 
  1. AN SSSR, Pushchino-na-Oke. Inst. Biologicheskoj Fiziki
Publication Date:
May 01, 1975
Product Type:
Journal Article
Reference Number:
AIX-08-321436; EDB-77-115419
Resource Relation:
Journal Name: Radiobiologiya; (USSR); Journal Volume: 15:3; Other Information: For English translation see the journal Radiobiology
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; CHOLESTEROL; METABOLISM; BIOLOGICAL RADIATION EFFECTS; CARBON 14 COMPOUNDS; CELL NUCLEI; IN VITRO; LABELLING; LIVER; MICROSOMES; MITOCHONDRIA; RADIATION DOSES; RATS; WHOLE-BODY IRRADIATION; ANIMALS; BIOLOGICAL EFFECTS; BODY; CELL CONSTITUENTS; DIGESTIVE SYSTEM; DOSES; EXTERNAL IRRADIATION; GLANDS; HYDROXY COMPOUNDS; IRRADIATION; LABELLED COMPOUNDS; MAMMALS; ORGANIC COMPOUNDS; ORGANOIDS; ORGANS; RADIATION EFFECTS; RODENTS; STEROIDS; STEROLS; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
7103820
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: RADOA
Submitting Site:
INIS
Size:
Pages: 452-454
Announcement Date:

Journal Article:

Citation Formats

Kaznacherev, Yu S, and Kolomiitseva, I K. Early radiation impairment of the cholesterol metabolism in organelles of rat liver cells. USSR: N. p., 1975. Web.
Kaznacherev, Yu S, & Kolomiitseva, I K. Early radiation impairment of the cholesterol metabolism in organelles of rat liver cells. USSR.
Kaznacherev, Yu S, and Kolomiitseva, I K. 1975. "Early radiation impairment of the cholesterol metabolism in organelles of rat liver cells." USSR.
@misc{etde_7103820,
title = {Early radiation impairment of the cholesterol metabolism in organelles of rat liver cells}
author = {Kaznacherev, Yu S, and Kolomiitseva, I K}
abstractNote = {The incorporation of 1-C/sup 14/-acetate into cholesterol of the nuclear, mitochondrial, microsomal and 105000 g-supernatant fractions isolated from the rat liver in norm and 60 min after the exposure to 1200 r has been investigated. An increase has been observed in the label uptake into liver cholesterol of irradiated rats. Intracellular distribution of the newly synthesized (labelled) cholesterol is substantially changed after irradiation: maximum label incorporation into the cholesterol is observed in the 105000 g-supernatant fraction, whereas, normally, the cholesterol of microsomal fraction has the highest specific activity.}
journal = {Radiobiologiya; (USSR)}
volume = {15:3}
journal type = {AC}
place = {USSR}
year = {1975}
month = {May}
}