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Cerebral radiation necrosis: vascular and glial features

Journal Article:

Abstract

Glial and vascular abnormalities in brain, simulating intracranial neoplasia, are described in a patient who received radiation to the pituitary region for treatment of an adenoma, 13 months before death. In addition to the expected changes of cerebral radionecrosis, four interesting features are cited: (1) diffuse hyperplasia of capillaries in the cerebral cortex with marked endothelial hypertrophy; (2) abundant, large multipolar bizarre cells in the perivascular connective tissues; (3) focal astrocytic proliferation with many cells resembling either Alzheimer type I astrocytes or neoplastic cells, and (4) radiation changes in the non-irradiated brain.
Publication Date:
Dec 21, 1976
Product Type:
Journal Article
Reference Number:
EDB-77-141832
Resource Relation:
Journal Name: Acta Neuropathol.; (German Democratic Republic); Journal Volume: 36:4
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BRAIN; DELAYED RADIATION EFFECTS; NECROSIS; RADIOINDUCTION; RADIOTHERAPY; SIDE EFFECTS; ADENOMAS; PATIENTS; PITUITARY GLAND; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CENTRAL NERVOUS SYSTEM; DISEASES; ENDOCRINE GLANDS; GLANDS; MEDICINE; NEOPLASMS; NERVOUS SYSTEM; NUCLEAR MEDICINE; ORGANS; PATHOLOGICAL CHANGES; RADIATION EFFECTS; RADIOLOGY; THERAPY; 560151* - Radiation Effects on Animals- Man
OSTI ID:
7094317
Research Organizations:
Univ. of Maryland, Baltimore
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: ANPTA
Submitting Site:
TIC
Size:
Pages: 381-385
Announcement Date:
Nov 01, 1977

Journal Article:

Citation Formats

Husain, M M, and Garcia, J H. Cerebral radiation necrosis: vascular and glial features. Germany: N. p., 1976. Web. doi:10.1007/BF00699643.
Husain, M M, & Garcia, J H. Cerebral radiation necrosis: vascular and glial features. Germany. doi:10.1007/BF00699643.
Husain, M M, and Garcia, J H. 1976. "Cerebral radiation necrosis: vascular and glial features." Germany. doi:10.1007/BF00699643. https://www.osti.gov/servlets/purl/10.1007/BF00699643.
@misc{etde_7094317,
title = {Cerebral radiation necrosis: vascular and glial features}
author = {Husain, M M, and Garcia, J H}
abstractNote = {Glial and vascular abnormalities in brain, simulating intracranial neoplasia, are described in a patient who received radiation to the pituitary region for treatment of an adenoma, 13 months before death. In addition to the expected changes of cerebral radionecrosis, four interesting features are cited: (1) diffuse hyperplasia of capillaries in the cerebral cortex with marked endothelial hypertrophy; (2) abundant, large multipolar bizarre cells in the perivascular connective tissues; (3) focal astrocytic proliferation with many cells resembling either Alzheimer type I astrocytes or neoplastic cells, and (4) radiation changes in the non-irradiated brain.}
doi = {10.1007/BF00699643}
journal = {Acta Neuropathol.; (German Democratic Republic)}
volume = {36:4}
journal type = {AC}
place = {Germany}
year = {1976}
month = {Dec}
}